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Lars Farde - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 
Area:
psychiatry, neuroimaging
Website:
http://ki.se/ki/jsp/polopoly.jsp?d=3858&l=sv

473 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Orhan F, Goiny M, Becklén M, Mathé L, Piehl F, Schwieler L, Fatouros-Bergman H, Farde L, Cervenka S, Sellgren CM, Engberg G, Erhardt S. CSF dopamine is elevated in first-episode psychosis and associates to symptom severity and cognitive performance. Schizophrenia Research. 257: 34-40. PMID 37271040 DOI: 10.1016/j.schres.2023.05.012  0.565
2023 Jangard S, Jayaram-Lindström N, Isacsson NH, Matheson GJ, Plavén-Sigray P, Franck J, Borg J, Farde L, Cervenka S. Striatal dopamine D2 receptor availability as a predictor of subsequent alcohol use in social drinkers. Addiction (Abingdon, England). PMID 36710462 DOI: 10.1111/add.16144  0.588
2022 Dahl K, Johnström P, Forsberg-Morén A, Gustafsson B, Miranda-Azpiazu P, Khani Y, Halldin C, Farde L, Elmore CS, Schou M. Synthesis and Preclinical Evaluation of [C]AZ11895530 for PET Imaging of the Serotonin 1A Receptor. Acs Chemical Neuroscience. PMID 35802379 DOI: 10.1021/acschemneuro.2c00205  0.403
2021 Plavén-Sigray P, Ikonen Victorsson P, Santillo A, Matheson GJ, Lee M, Collste K, Fatouros-Bergman H, Sellgren CM, Erhardt S, Agartz I, Halldin C, Farde L, Cervenka S. Thalamic dopamine D2-receptor availability in schizophrenia: a study on antipsychotic-naive patients with first-episode psychosis and a meta-analysis. Molecular Psychiatry. PMID 34759359 DOI: 10.1038/s41380-021-01349-x  0.612
2021 Lee M, Fatouros-Bergman H, Plavén-Sigray P, Ikonen Victorsson P, Sellgren CM, Erhardt S, Flyckt L, Farde L, Cervenka S. No association between cortical dopamine D2 receptor availability and cognition in antipsychotic-naive first-episode psychosis. Npj Schizophrenia. 7: 46. PMID 34548499 DOI: 10.1038/s41537-021-00176-x  0.609
2020 Freiburghaus T, Svensson JE, Matheson GJ, Plavén-Sigray P, Lundberg J, Farde L, Cervenka S. Low convergent validity of [C]raclopride binding in extrastriatal brain regions: a PET study of within-subject correlations with [C]FLB 457. Neuroimage. 117523. PMID 33144221 DOI: 10.1016/j.neuroimage.2020.117523  0.65
2020 Varnäs K, Finnema SJ, Johnström P, Arakawa R, Halldin C, Eriksson LI, Farde L. Effects of sevoflurane anaesthesia on radioligand binding to monoamine oxidase-B in vivo. British Journal of Anaesthesia. PMID 33036760 DOI: 10.1016/j.bja.2020.08.052  0.342
2020 Andersson M, Tangen Ä, Farde L, Bölte S, Halldin C, Borg J, Lundberg J. Serotonin transporter availability in adults with autism-a positron emission tomography study. Molecular Psychiatry. PMID 32848204 DOI: 10.1038/S41380-020-00868-3  0.31
2020 Tjerkaski J, Cervenka S, Farde L, Matheson GJ. Kinfitr - an open-source tool for reproducible PET modelling: validation and evaluation of test-retest reliability. Ejnmmi Research. 10: 77. PMID 32642865 DOI: 10.1186/s13550-020-00664-8  0.57
2020 Matheson GJ, Plavén-Sigray P, Louzolo A, Borg J, Farde L, Petrovic P, Cervenka S. Dopamine D1 receptor availability is not associated with delusional ideation measures of psychosis proneness. Schizophrenia Research. PMID 32616361 DOI: 10.1016/J.Schres.2020.06.001  0.671
2020 Cselényi Z, Jucaite A, Kristensson C, Stenkrona P, Ewing P, Varrone A, Johnström P, Schou M, Vazquez-Romero A, Moein MM, Bolin M, Siikanen J, Grybäck P, Larsson B, Halldin C, ... ... Farde L, et al. Quantification and reliability of [C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung - a test-retest PET study in control subjects. Ejnmmi Research. 10: 59. PMID 32495011 DOI: 10.1186/S13550-020-00634-0  0.421
2020 Nag S, Varnas K, Arakawa R, Jahan M, Schou M, Farde L, Halldin C. Synthesis, biodistribution and radiation dosimetry of a novel mGluR5 radioligand: [18F]AZD9272. Acs Chemical Neuroscience. PMID 32167745 DOI: 10.1021/Acschemneuro.9B00680  0.341
2020 Tiger M, Svensson J, Liberg B, Saijo T, Schain M, Halldin C, Farde L, Lundberg J. A [ C]raclopride positron emission tomography study of dopamine-D receptor binding in patients with severe major depressive episodes before and after electroconvulsive therapy and compared to control subjects. Psychiatry and Clinical Neurosciences. PMID 31943514 DOI: 10.1111/Pcn.12980  0.315
2020 Victorsson P, Plavén-Sigray P, Matheson G, Santillo A, Lee M, Collste K, Fatouros-Bergman H, Agartz I, Halldin C, Farde L, Cervenka S. M7. LOWER THALAMIC DOPAMINE D2-RECEPTOR BINDING IN DRUG-NAIVE PATIENTS WITH PSYCHOSIS – A REPLICATION STUDY USING POSITRON EMISSION TOMOGRAPHY Schizophrenia Bulletin. 46: S135-S136. DOI: 10.1093/Schbul/Sbaa030.319  0.69
2019 Svensson JE, Schain M, Plavén-Sigray P, Cervenka S, Tiger M, Nord M, Halldin C, Farde L, Lundberg J. In response to the letter "[C]raclopride and extrastriatal binding to D2/3 receptors". Neuroimage. 116371. PMID 31756518 DOI: 10.1016/J.Neuroimage.2019.116371  0.636
2019 Lindberg A, Arakawa R, Nogami T, Nag S, Schou M, Elmore CS, Farde L, Pike VW, Halldin C. Potential for imaging the high-affinity state of the 5-HT receptor: a comparison of three PET radioligands with differing intrinsic activity. Ejnmmi Research. 9: 100. PMID 31754940 DOI: 10.1186/S13550-019-0570-1  0.399
2019 Varnäs K, Cselényi Z, Arakawa R, Nag S, Stepanov V, Moein MM, Johnström P, Kingston L, Elmore CS, Halldin C, Farde L. The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans. Neuropharmacology. 107809. PMID 31589885 DOI: 10.1016/J.Neuropharm.2019.107809  0.467
2019 Svensson JE, Schain M, Plavén-Sigray P, Cervenka S, Tiger M, Nord M, Halldin C, Farde L, Lundberg J. Validity and reliability of extrastriatal [C]raclopride binding quantification in the living human brain. Neuroimage. 116143. PMID 31473354 DOI: 10.1016/J.Neuroimage.2019.116143  0.684
2019 Tuisku J, Plavén-Sigray P, Gaiser EC, Airas L, Al-Abdulrasul H, Brück A, Carson RE, Chen MK, Cosgrove KP, Ekblad L, Esterlis I, Farde L, Forsberg A, Halldin C, Helin S, et al. Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre [C]PBR28 HRRT PET study. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31363804 DOI: 10.1007/S00259-019-04403-7  0.621
2019 Forsberg A, Lampa J, Estelius J, Cervenka S, Farde L, Halldin C, Lekander M, Olgart Höglund C, Kosek E. Disease activity in rheumatoid arthritis is inversely related to cerebral TSPO binding assessed by [C]PBR28 positron emission tomography. Journal of Neuroimmunology. 334: 577000. PMID 31260948 DOI: 10.1016/J.Jneuroim.2019.577000  0.593
2019 Yang KC, Stepanov V, Amini N, Martinsson S, Takano A, Bundgaard C, Bang-Andersen B, Sanchez C, Halldin C, Farde L, Finnema SJ. Effect of clinically relevant doses of vortioxetine and citalopram on serotonergic PET markers in the nonhuman primate brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31216565 DOI: 10.1038/S41386-019-0442-4  0.44
2019 Varrone A, Varnäs K, Jucaite A, Cselényi Z, Johnström P, Schou M, Vazquez-Romero A, Moein MM, Halldin C, Brown AP, Vishwanathan K, Farde L. A PET study in healthy subjects of brain exposure of C-labelled osimertinib - A drug intended for treatment of brain metastases in non-small cell lung cancer. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19843776. PMID 31006308 DOI: 10.1177/0271678X19843776  0.429
2019 Stenkrona P, Matheson GJ, Halldin C, Cervenka S, Farde L. D1-Dopamine Receptor Availability in First-Episode Neuroleptic Naive Psychosis Patients. The International Journal of Neuropsychopharmacology. PMID 30958880 DOI: 10.1093/Ijnp/Pyz017  0.691
2019 Schou M, Ewing P, Cselenyi Z, Fridén M, Takano A, Halldin C, Farde L. Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator. Ejnmmi Research. 9: 9. PMID 30694407 DOI: 10.1186/S13550-019-0479-8  0.397
2018 Jahan M, Johnström P, Selvaraju RK, Svedberg M, Winzell MS, Bernström J, Kingston L, Schou M, Jia Z, Skrtic S, Johansson L, Korsgren O, Farde L, Halldin C, Eriksson O. The development of a GPR44 targeting radioligand [C]AZ12204657 for in vivo assessment of beta cell mass. Ejnmmi Research. 8: 113. PMID 30588560 DOI: 10.1186/S13550-018-0465-6  0.305
2018 Plavén-Sigray P, Matheson GJ, Cselényi Z, Jucaite A, Farde L, Cervenka S. Test-retest reliability and convergent validity of (R)-[C]PK11195 outcome measures without arterial input function. Ejnmmi Research. 8: 102. PMID 30498919 DOI: 10.1186/s13550-018-0455-8  0.613
2018 Griffioen G, Matheson GJ, Cervenka S, Farde L, Borg J. Serotonin 5-HT receptor binding and self-transcendence in healthy control subjects-a replication study using Bayesian hypothesis testing. Peerj. 6: e5790. PMID 30479884 DOI: 10.7717/peerj.5790  0.628
2018 Varnäs K, Cselényi Z, Jucaite A, Halldin C, Svenningsson P, Farde L, Varrone A. PET imaging of [C]PBR28 in Parkinson's disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding. European Journal of Nuclear Medicine and Molecular Imaging. PMID 30270409 DOI: 10.1007/S00259-018-4161-6  0.396
2018 Orhan F, Schwieler L, Fatouros-Bergman H, Malmqvist A, Cervenka S, Collste K, Flyckt L, Farde L, Sellgren CM, Piehl F, Engberg G, Erhardt S. Increased number of monocytes and plasma levels of MCP-1 and YKL-40 in first-episode psychosis. Acta Psychiatrica Scandinavica. 138: 432-440. PMID 30132802 DOI: 10.1111/acps.12944  0.49
2018 Stenkrona P, Matheson GJ, Cervenka S, Sigray PP, Halldin C, Farde L. [C]SCH23390 binding to the D-dopamine receptor in the human brain-a comparison of manual and automated methods for image analysis. Ejnmmi Research. 8: 74. PMID 30069645 DOI: 10.1186/S13550-018-0416-2  0.722
2018 Yang KC, Takano A, Halldin C, Farde L, Finnema SJ. Serotonin concentration enhancers at clinically relevant doses reduce [C]AZ10419369 binding to the 5-HT receptors in the nonhuman primate brain. Translational Psychiatry. 8: 132. PMID 30013068 DOI: 10.1038/S41398-018-0178-7  0.453
2018 Varnäs K, Juréus A, Finnema SJ, Johnström P, Raboisson P, Amini N, Takano A, Stepanov V, Halldin C, Farde L. The metabotropic glutamate receptor 5 radioligand [C]AZD9272 identifies unique binding sites in primate brain. Neuropharmacology. PMID 29608920 DOI: 10.1016/J.Neuropharm.2018.03.039  0.458
2018 Plavén-Sigray P, Matheson GJ, Gustavsson P, Stenkrona P, Halldin C, Farde L, Cervenka S. Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study. Plos One. 13: e0193770. PMID 29543812 DOI: 10.1371/Journal.Pone.0193770  0.673
2018 Farde L, Plavén-Sigray P, Borg J, Cervenka S. Brain neuroreceptor density and personality traits: towards dimensional biomarkers for psychiatric disorders. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29483342 DOI: 10.1098/rstb.2017.0156  0.586
2018 Fazio P, Svenningsson P, Cselényi Z, Halldin C, Farde L, Varrone A. Nigrostriatal dopamine transporter availability in early Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29436751 DOI: 10.1002/Mds.27316  0.331
2018 Benlloch JM, González AJ, Pani R, Preziosi E, Jackson C, Murphy J, Barberá J, Correcher C, Aussenhofer S, Gareis D, Visvikis D, Bert J, Langstrom B, Farde L, Toth M, et al. The MINDVIEW project: First results. European Psychiatry : the Journal of the Association of European Psychiatrists. PMID 29398564 DOI: 10.1016/J.Eurpsy.2018.01.002  0.429
2018 Vishwanathan K, Varrone A, Varnas K, Jucaite A, Cselenyi Z, Johnstrom P, Schou M, Vasquez-Romero A, Moein MM, Halldin C, Brown AP, Farde L. Abstract CT013: Osimertinib displays high brain exposure in healthy subjects with intact blood-brain barrier: a microdose positron emission tomography (PET) study with 11C-labelled osimertinib Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Ct013  0.402
2017 Lindberg A, Nag S, Schou M, Takano A, Matsumoto J, Amini N, Elmore CS, Farde L, Pike VW, Halldin C. [(11)C]AZ10419096 - a full antagonist PET radioligand for imaging brain 5-HT1B receptors. Nuclear Medicine and Biology. 54: 34-40. PMID 28950161 DOI: 10.1016/J.Nucmedbio.2017.07.007  0.525
2017 Arakawa R, Farde L, Matsumoto J, Kanegawa N, Yakushev I, Yang KC, Takano A. Potential Effect of Prolonged Sevoflurane Anesthesia on the Kinetics of [(11)C]Raclopride in Non-human Primates. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 28916921 DOI: 10.1007/S11307-017-1120-8  0.433
2017 Yang KC, Stepanov V, Martinsson S, Ettrup A, Takano A, Knudsen GM, Halldin C, Farde L, Finnema SJ. Fenfluramine Reduces [11C]Cimbi-36 Binding to the 5-HT2A Receptor in the Nonhuman Primate Brain. The International Journal of Neuropsychopharmacology. 20: 683-691. PMID 28911007 DOI: 10.1093/Ijnp/Pyx051  0.518
2017 Matheson GJ, Plavén-Sigray P, Forsberg A, Varrone A, Farde L, Cervenka S. Assessment of simplified ratio-based approaches for quantification of PET [(11)C]PBR28 data. Ejnmmi Research. 7: 58. PMID 28733954 DOI: 10.1186/S13550-017-0304-1  0.644
2017 Matheson GJ, Stenkrona P, Cselényi Z, Plavén-Sigray P, Halldin C, Farde L, Cervenka S. Reliability of Volumetric and Surface-Based Normalisation and Smoothing Techniques for PET Analysis of the Cortex: A Test-Retest Analysis using [(11)C]SCH-23390. Neuroimage. PMID 28419852 DOI: 10.1016/J.Neuroimage.2017.04.031  0.624
2017 Forsberg A, Cervenka S, Jonsson Fagerlund M, Rasmussen LS, Zetterberg H, Erlandsson Harris H, Stridh P, Christensson E, Granström A, Schening A, Dymmel K, Knave N, Terrando N, Maze M, Borg J, ... ... Farde L, et al. The immune response of the human brain to abdominal surgery. Annals of Neurology. PMID 28253549 DOI: 10.1002/Ana.24909  0.591
2017 Collste K, Plavén-Sigray P, Fatouros-Bergman H, Victorsson P, Schain M, Forsberg A, Amini N, Aeinehband S, Erhardt S, Halldin C, Flyckt L, Farde L, Cervenka S. Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [(11)C]PBR28. Molecular Psychiatry. PMID 28194003 DOI: 10.1038/mp.2016.247  0.613
2017 Johnström P, Gutierrez PM, Varnäs K, Schou M, Takano A, Jones L, Mugundu G, McCoon P, Lyne P, Infante J, Falchook G, Patel M, Karlix J, Merchant M, Clarke J, ... ... Farde L, et al. Abstract 2641: AZD4635 A2Areceptor occupancy in cynomolgus monkey using PET and its application to an oncology clinical development program Cancer Research. 77: 2641-2641. DOI: 10.1158/1538-7445.Am2017-2641  0.409
2017 Collste K, Orhan F, Erhardt S, Schwieler L, Flyckt L, Farde L, Engberg G, Cervenka S. Associations between central chemokine levels and glial activation in first episode psychosis – a positron emission tomography study European Neuropsychopharmacology. 27. DOI: 10.1016/S0924-977X(17)31329-9  0.592
2016 Jucaite A, Cselényi Z, Lappalainen J, McCarthy DJ, Lee CM, Nyberg S, Varnäs K, Stenkrona P, Halldin C, Cross A, Farde L. GABAA receptor occupancy by subtype selective GABAAα2,3 modulators: PET studies in humans. Psychopharmacology. PMID 28013354 DOI: 10.1007/S00213-016-4506-4  0.367
2016 Yang KC, Stepanov V, Amini N, Martinsson S, Takano A, Nielsen J, Bundgaard C, Bang-Andersen B, Grimwood S, Halldin C, Farde L, Finnema SJ. Characterization of [(11)C]Lu AE92686 as a PET radioligand for phosphodiesterase 10A in the nonhuman primate brain. European Journal of Nuclear Medicine and Molecular Imaging. PMID 27817159 DOI: 10.1007/S00259-016-3544-9  0.473
2016 Varnas K, Jureus A, Johnstrom P, Ahlgren C, Schott P, Schou M, Gruber S, Jerning E, Malmborg J, Halldin C, Afzelius L, Farde L. Integrated strategy for use of PET in non-human primate to confirm multi-target occupancy of novel psychotropic drugs: an example with AZD3676. The Journal of Pharmacology and Experimental Therapeutics. PMID 27402278 DOI: 10.1124/Jpet.116.234146  0.476
2016 Tiger M, Farde L, Rück C, Varrone A, Forsberg A, Lindefors N, Halldin C, Lundberg J. Low serotonin1B receptor binding potential in the anterior cingulate cortex in drug-free patients with recurrent major depressive disorder. Psychiatry Research. 253: 36-42. PMID 27269199 DOI: 10.1016/J.Pscychresns.2016.04.016  0.464
2016 Sonni I, Fazio P, Schain M, Halldin C, Svenningsson P, Farde L, Varrone A. Optimal acquisition time window and simplified quantification of dopamine transporter availability using 18F-FE-PE2I in healthy controls and Parkinson's disease patients. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27230923 DOI: 10.2967/Jnumed.115.171231  0.338
2016 Fazio P, Schain M, Varnäs K, Halldin C, Farde L, Varrone A. Mapping the distribution of serotonin transporter in the human brainstem with high resolution PET: Validation using post-mortem autoradiography data. Neuroimage. PMID 26994829 DOI: 10.1016/J.Neuroimage.2016.03.019  0.387
2016 Varnäs K, Finnema SJ, Stepanov V, Takano A, Tóth M, Svedberg M, Nielsen SM, Khanzhin NA, Juhl K, Bang-Andersen B, Halldin C, Farde L. Neurokinin-3 receptor binding in guinea pig, monkey and human brain: In vitro and in vivo imaging using the novel radioligand, [18F]Lu AF10628. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26993630 DOI: 10.1093/Ijnp/Pyw023  0.437
2016 Kanegawa N, Collste K, Forsberg A, Schain M, Arakawa R, Jucaite A, Lekander M, Höglund CO, Kosek E, Lampa J, Halldin C, Farde L, Varrone A, Cervenka S. In vivo evidence of a functional association between immune cells in blood and brain in healthy human subjects. Brain, Behavior, and Immunity. PMID 26820224 DOI: 10.1016/J.Bbi.2016.01.019  0.633
2016 Kanegawa N, Collste K, Forsberg A, Schain M, Arakawa R, Jucaite A, Lekander M, Höglund CO, Kosek E, Lampa J, Halldin C, Farde L, Varrone A, Cervenka S. Abstract # 1847 Cross-sectional and longitudinal associations between immune cells in blood and brain – A TSPO PET study in healthy control subjects Brain, Behavior, and Immunity. 57: e38. DOI: 10.1016/J.Bbi.2016.07.127  0.635
2015 Borg J, Cervenka S, Kuja-Halkola R, Matheson GJ, Jönsson EG, Lichtenstein P, Henningsson S, Ichimiya T, Larsson H, Stenkrona P, Halldin C, Farde L. Contribution of non-genetic factors to dopamine and serotonin receptor availability in the adult human brain. Molecular Psychiatry. PMID 26821979 DOI: 10.1038/Mp.2015.147  0.713
2015 Schou M, Varnas K, Jureus A, Ahlgren C, Malmquist J, Häggkvist J, Tari L, Wesolowski SS, Throner SR, Brown DG, Nilsson M, Johnström P, Finnema SJ, Nakao R, Amini N, ... ... Farde L, et al. Discovery and preclinical validation of [11C]AZ13153556, a novel probe for the histamine type-3 receptor. Acs Chemical Neuroscience. PMID 26529287 DOI: 10.1021/Acschemneuro.5B00268  0.454
2015 Collste K, Forsberg A, Varrone A, Amini N, Aeinehband S, Yakushev I, Halldin C, Farde L, Cervenka S. Test-retest reproducibility of [(11)C]PBR28 binding to TSPO in healthy control subjects. European Journal of Nuclear Medicine and Molecular Imaging. PMID 26293827 DOI: 10.1007/S00259-015-3149-8  0.652
2015 Rahman O, Takano A, Amini N, Dahl K, Kanegawa N, Långström B, Farde L, Halldin C. Synthesis of ([(11)C]carbonyl)raclopride and a comparison with ([(11)C]methyl)raclopride in a monkey PET study. Nuclear Medicine and Biology. 42: 893-8. PMID 26272268 DOI: 10.1016/J.Nucmedbio.2015.07.003  0.395
2015 Jucaite A, Svenningsson P, Rinne JO, Cselényi Z, Varnäs K, Johnström P, Amini N, Kirjavainen A, Helin S, Minkwitz M, Kugler AR, Posener JA, Budd S, Halldin C, Varrone A, ... Farde L, et al. Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease. Brain : a Journal of Neurology. 138: 2687-700. PMID 26137956 DOI: 10.1093/Brain/Awv184  0.368
2015 Mattsson P, Forsberg A, Persson J, Nyberg L, Nilsson LG, Halldin C, Farde L. β-Amyloid binding in elderly subjects with declining or stable episodic memory function measured with PET and [(11)C]AZD2184. European Journal of Nuclear Medicine and Molecular Imaging. PMID 26115835 DOI: 10.1007/S00259-015-3103-9  0.352
2015 Finnema SJ, Halldin C, Bang-Andersen B, Bundgaard C, Farde L. Serotonin transporter occupancy by escitalopram and citalopram in the non-human primate brain: a [(11)C]MADAM PET study. Psychopharmacology. 232: 4159-67. PMID 25980484 DOI: 10.1007/S00213-015-3961-7  0.522
2015 Finnema SJ, Scheinin M, Shahid M, Lehto J, Borroni E, Bang-Andersen B, Sallinen J, Wong E, Farde L, Halldin C, Grimwood S. Application of cross-species PET imaging to assess neurotransmitter release in brain. Psychopharmacology. PMID 25921033 DOI: 10.1007/S00213-015-3938-6  0.461
2015 Varrone A, Svenningsson P, Marklund P, Fatouros-Bergman H, Forsberg A, Halldin C, Nilsson LG, Farde L. 5-HT1B receptor imaging and cognition: a positron emission tomography study in control subjects and Parkinson's disease patients. Synapse (New York, N.Y.). 69: 365-74. PMID 25914348 DOI: 10.1002/Syn.21823  0.36
2015 Cselényi Z, Farde L. Quantification of blood flow-dependent component in estimates of beta-amyloid load obtained using quasi-steady-state standardized uptake value ratio. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 25873425 DOI: 10.1038/jcbfm.2015.66  0.341
2015 Schou M, Varnäs K, Lundquist S, Nakao R, Amini N, Takano A, Finnema SJ, Halldin C, Farde L. Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 25813017 DOI: 10.1093/Ijnp/Pyv036  0.34
2015 Fazio P, Svenningsson P, Forsberg A, Jönsson EG, Amini N, Nakao R, Nag S, Halldin C, Farde L, Varrone A. Quantitative Analysis of ¹⁸F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 714-20. PMID 25791993 DOI: 10.2967/Jnumed.114.152421  0.335
2015 Hjorth S, Karlsson C, Jucaite A, Varnäs K, Wählby Hamrén U, Johnström P, Gulyás B, Donohue SR, Pike VW, Halldin C, Farde L. A PET study comparing receptor occupancy by five selective cannabinoid 1 receptor antagonists in non-human primates. Neuropharmacology. PMID 25791528 DOI: 10.1016/J.Neuropharm.2015.03.002  0.716
2015 Matheson GJ, Schain M, Almeida R, Lundberg J, Cselényi Z, Borg J, Varrone A, Farde L, Cervenka S. Diurnal and seasonal variation of the brain serotonin system in healthy male subjects. Neuroimage. 112: 225-31. PMID 25772667 DOI: 10.1016/J.Neuroimage.2015.03.007  0.646
2015 Johnström P, Bergman L, Varnäs K, Malmquist J, Halldin C, Farde L. Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing. Nuclear Medicine and Biology. 42: 555-60. PMID 25726760 DOI: 10.1016/J.Nucmedbio.2015.02.001  0.393
2015 Finnema SJ, Hughes ZA, Haaparanta-Solin M, Stepanov V, Nakao R, Varnäs K, Varrone A, Arponen E, Marjamäki P, Pohjanoksa K, Vuorilehto L, Babalola PA, Solin O, Grimwood S, Sallinen J, ... Farde L, et al. Amphetamine decreases α2C-adrenoceptor binding of [11C]ORM-13070: a PET study in the primate brain. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522417 DOI: 10.1093/Ijnp/Pyu081  0.371
2015 Dahl K, Schou M, Ulin J, Sjöberg CO, Farde L, Halldin C. 11C-carbonylation reactions using gas-liquid segmented microfluidics Rsc Advances. 5: 88886-88889. DOI: 10.1039/C5Ra20646D  0.346
2015 Fatouros-Bergman H, Cervenka C, Flyckt L, Edman G, Schwieler L, Ikonen P, Collste K, Piehl F, Agartz I, Engberg G, Erhardt S, Farde L. Cognitive Performance in Drug-naÏve First Episode Schizophrenia (FES) Patients European Psychiatry. 30: 277. DOI: 10.1016/S0924-9338(15)30225-X  0.306
2015 Finnema SJ, Halldin C, Bang-Andersen B, Bundgaard C, Farde L. Serotonin transporter occupancy by escitalopram and citalopram in the non-human primate brain: a [11C]MADAM PET study Psychopharmacology. DOI: 10.1007/s00213-015-3961-7  0.345
2014 Fridén M, Wennerberg M, Antonsson M, Sandberg-Ställ M, Farde L, Schou M. Identification of positron emission tomography (PET) tracer candidates by prediction of the target-bound fraction in the brain. Ejnmmi Research. 4: 50. PMID 26116114 DOI: 10.1186/s13550-014-0050-6  0.438
2014 Nord M, Cselenyi Z, Forsberg A, Rosenqvist G, Tiger M, Lundberg J, Varrone A, Farde L. Distinct regional age effects on [11C]AZ10419369 binding to 5-HT1B receptors in the human brain. Neuroimage. 103: 303-8. PMID 25255943 DOI: 10.1016/J.Neuroimage.2014.09.040  0.395
2014 Plavén-Sigray P, Gustavsson P, Farde L, Borg J, Stenkrona P, Nyberg L, Bäckman L, Cervenka S. Dopamine D1 receptor availability is related to social behavior: a positron emission tomography study. Neuroimage. 102: 590-5. PMID 25134976 DOI: 10.1016/J.Neuroimage.2014.08.018  0.638
2014 Fatouros-Bergman H, Cervenka S, Flyckt L, Edman G, Farde L. Meta-analysis of cognitive performance in drug-naïve patients with schizophrenia. Schizophrenia Research. 158: 156-62. PMID 25086658 DOI: 10.1016/j.schres.2014.06.034  0.496
2014 Tiger M, Rück C, Forsberg A, Varrone A, Lindefors N, Halldin C, Farde L, Lundberg J. Reduced 5-HT(1B) receptor binding in the dorsal brain stem after cognitive behavioural therapy of major depressive disorder. Psychiatry Research. 223: 164-70. PMID 24916155 DOI: 10.1016/J.Pscychresns.2014.05.011  0.433
2014 Schain M, Varnäs K, Cselényi Z, Halldin C, Farde L, Varrone A. Evaluation of two automated methods for PET region of interest analysis. Neuroinformatics. 12: 551-62. PMID 24880728 DOI: 10.1007/S12021-014-9233-6  0.372
2014 Finnema SJ, Stepanov V, Nakao R, Sromek AW, Zhang T, Neumeyer JL, George SR, Seeman P, Stabin MG, Jonsson C, Farde L, Halldin C. (18)F-MCL-524, an (18)F-Labeled Dopamine D2 and D3 Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1164-70. PMID 24790219 DOI: 10.2967/Jnumed.113.133876  0.492
2014 Ito H, Shimada H, Shinotoh H, Takano H, Sasaki T, Nogami T, Suzuki M, Nagashima T, Takahata K, Seki C, Kodaka F, Eguchi Y, Fujiwara H, Kimura Y, Hirano S, ... ... Farde L, et al. Quantitative Analysis of Amyloid Deposition in Alzheimer Disease Using PET and the Radiotracer ¹¹C-AZD2184. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 932-8. PMID 24732152 DOI: 10.2967/jnumed.113.133793  0.364
2014 Varrone A, Svenningsson P, Forsberg A, Varnäs K, Tiger M, Nakao R, Halldin C, Nilsson LG, Farde L. Positron emission tomography imaging of 5-hydroxytryptamine1B receptors in Parkinson's disease. Neurobiology of Aging. 35: 867-75. PMID 24126162 DOI: 10.1016/J.Neurobiolaging.2013.08.025  0.353
2014 Nord M, Finnema SJ, Schain M, Halldin C, Farde L. Test-retest reliability of [11C]AZ10419369 binding to 5-HT(1B) receptors in human brain. European Journal of Nuclear Medicine and Molecular Imaging. 41: 301-7. PMID 24006152 DOI: 10.1007/S00259-013-2529-1  0.38
2014 Schou M, Varnäs K, Sandell J, Johnström P, Cselenyi Z, Svensson S, Nakao R, Amini N, Bergman L, Sumic A, Gulyas B, Lindström-Böö E, Halldin C, Farde L. Synthesis, radiolabeling, and in vivo pharmacokinetic evaluation of the amyloid beta radioligand [11C]AZD4694 in nonhuman primates. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 173-9. PMID 24002613 DOI: 10.1007/S11307-013-0666-3  0.709
2013 Nagy K, Tóth M, Major P, Patay G, Egri G, Häggkvist J, Varrone A, Farde L, Halldin C, Gulyás B. Performance evaluation of the small-animal nanoScan PET/MRI system. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1825-32. PMID 23990683 DOI: 10.2967/Jnumed.112.119065  0.626
2013 Airaksinen AJ, Finnema SJ, Balle T, Varnäs K, Bang-Andersen B, Gulyás B, Farde L, Halldin C. Radiosynthesis and evaluation of new α1-adrenoceptor antagonists as PET radioligands for brain imaging. Nuclear Medicine and Biology. 40: 747-54. PMID 23810488 DOI: 10.1016/J.Nucmedbio.2013.05.007  0.719
2013 Nyberg S, Jucaite A, Takano A, KÃ¥gedal M, Cselényi Z, Halldin C, Farde L. Norepinephrine transporter occupancy in the human brain after oral administration of quetiapine XR. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2235-44. PMID 23809226 DOI: 10.1017/S1461145713000680  0.483
2013 Varnäs K, Varrone A, Farde L. Modeling of PET data in CNS drug discovery and development. Journal of Pharmacokinetics and Pharmacodynamics. 40: 267-79. PMID 23660778 DOI: 10.1007/S10928-013-9320-6  0.386
2013 Schain M, Benjaminsson S, Varnäs K, Forsberg A, Halldin C, Lansner A, Farde L, Varrone A. Arterial input function derived from pairwise correlations between PET-image voxels. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1058-65. PMID 23571279 DOI: 10.1038/Jcbfm.2013.47  0.36
2013 Andersson JD, Seneca N, Truong P, Wensbo D, Raboisson P, Farde L, Halldin C. Palladium mediated ¹¹C-cyanation and characterization in the non-human primate brain of the novel mGluR5 radioligand [¹¹C]AZD9272. Nuclear Medicine and Biology. 40: 547-53. PMID 23541825 DOI: 10.1016/J.Nucmedbio.2012.12.012  0.484
2013 Finnema SJ, Bang-Andersen B, Jørgensen M, Christoffersen CT, Gulyás B, Wikström HV, Farde L, Halldin C. The dopamine D₁ receptor agonist (S)-[¹¹C]N-methyl-NNC 01-0259 is not sensitive to changes in dopamine concentration--a positron emission tomography examination in the monkey brain. Synapse (New York, N.Y.). 67: 586-95. PMID 23504964 DOI: 10.1002/syn.21664  0.757
2013 Varnäs K, Jučaite A, McCarthy DJ, Stenkrona P, Nord M, Halldin C, Farde L, Kanes S. A PET study with [11C]AZ10419369 to determine brain 5-HT1B receptor occupancy of zolmitriptan in healthy male volunteers. Cephalalgia : An International Journal of Headache. 33: 853-60. PMID 23430984 DOI: 10.1177/0333102413476372  0.495
2013 Schou M, Varnäs K, Jucaite A, Gulyás B, Halldin C, Farde L. Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate. Nuclear Medicine and Biology. 40: 410-4. PMID 23352602 DOI: 10.1016/J.Nucmedbio.2012.10.011  0.725
2013 Forsberg A, Juréus A, Cselényi Z, Eriksdotter M, Freund-Levi Y, Jeppsson F, Swahn BM, Sandell J, Julin P, Schou M, Andersson J, Johnström P, Varnäs K, Halldin C, Farde L, et al. Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patients. European Journal of Nuclear Medicine and Molecular Imaging. 40: 580-93. PMID 23324871 DOI: 10.1007/S00259-012-2322-6  0.415
2013 Kodaka F, Ito H, Kimura Y, Fujie S, Takano H, Fujiwara H, Sasaki T, Nakayama K, Halldin C, Farde L, Suhara T. Test-retest reproducibility of dopamine D2/3 receptor binding in human brain measured by PET with [11C]MNPA and [11C]raclopride. European Journal of Nuclear Medicine and Molecular Imaging. 40: 574-9. PMID 23238524 DOI: 10.1007/S00259-012-2312-8  0.466
2013 de Manzano Ö, Cervenka S, Jucaite A, Hellenäs O, Farde L, Ullén F. Individual differences in the proneness to have flow experiences are linked to dopamine D2-receptor availability in the dorsal striatum. Neuroimage. 67: 1-6. PMID 23128075 DOI: 10.1016/J.Neuroimage.2012.10.072  0.625
2013 Takano A, Halldin C, Farde L. SERT and NET occupancy by venlafaxine and milnacipran in nonhuman primates: a PET study. Psychopharmacology. 226: 147-53. PMID 23090625 DOI: 10.1007/S00213-012-2901-Z  0.412
2013 Schain M, Tóth M, Cselényi Z, Arakawa R, Halldin C, Farde L, Varrone A. Improved mapping and quantification of serotonin transporter availability in the human brainstem with the HRRT. European Journal of Nuclear Medicine and Molecular Imaging. 40: 228-37. PMID 23076621 DOI: 10.1007/S00259-012-2260-3  0.444
2013 Guterstam J, Jayaram-Lindström N, Cervenka S, Frost JJ, Farde L, Halldin C, Franck J. Effects of amphetamine on the human brain opioid system--a positron emission tomography study. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 763-9. PMID 22932428 DOI: 10.1017/S1461145712000818  0.649
2013 Jucaite A, Cselényi Z, Varrone A, Varnäs K, Johnström P, Halldin C, Salter H, McLoughlin M, Rinne J, Svenningsson P, Alexander R, Kugler A, Farde L. 145. Translocator protein (TSPO) as a biomarker of microglia activation: PET imaging using [11C]PBR28 in Parkinson’s disease Brain, Behavior, and Immunity. 32: e42. DOI: 10.1016/J.Bbi.2013.07.157  0.464
2012 Ju?aite A, Cselényi Z, Arvidsson A, Ahlberg G, Julin P, Varnäs K, Stenkrona P, Andersson J, Halldin C, Farde L. Kinetic analysis and test-retest variability of the radioligand [11C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects. Ejnmmi Research. 2: 15. PMID 22524272 DOI: 10.1186/2191-219X-2-15  0.427
2012 Cselényi Z, Jönhagen ME, Forsberg A, Halldin C, Julin P, Schou M, Johnström P, Varnäs K, Svensson S, Farde L. Clinical validation of 18F-AZD4694, an amyloid-β-specific PET radioligand. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 415-24. PMID 22323782 DOI: 10.2967/Jnumed.111.094029  0.391
2012 Lundberg J, Tiger M, Landén M, Halldin C, Farde L. Serotonin transporter occupancy with TCAs and SSRIs: a PET study in patients with major depressive disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1167-72. PMID 22243688 DOI: 10.1017/S1461145711001945  0.364
2012 Schain M, Tóth M, Cselényi Z, Stenkrona P, Halldin C, Farde L, Varrone A. Quantification of serotonin transporter availability with [11C]MADAM--a comparison between the ECAT HRRT and HR systems. Neuroimage. 60: 800-7. PMID 22227138 DOI: 10.1016/J.Neuroimage.2011.12.047  0.361
2012 Finnema SJ, Varrone A, Hwang TJ, Halldin C, Farde L. Confirmation of fenfluramine effect on 5-HT(1B) receptor binding of [(11)C]AZ10419369 using an equilibrium approach. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 685-95. PMID 22167236 DOI: 10.1038/Jcbfm.2011.172  0.492
2012 Odano I, Varrone A, Savic I, Ciumas C, Karlsson P, Jucaite A, Halldin C, Farde L. Quantitative PET analyses of regional [11C]PE2I binding to the dopamine transporter--application to juvenile myoclonic epilepsy. Neuroimage. 59: 3582-93. PMID 22056530 DOI: 10.1016/J.Neuroimage.2011.10.067  0.468
2012 Sestini S, Halldin C, Mansi L, Castagnoli A, Farde L. Pharmacokinetic analysis of plasma curves obtained after i.v. injection of the PET radioligand [11C] raclopride provides a likely explanation for rapid radioligand metabolism. Journal of Cellular Physiology. 227: 1663-9. PMID 21678422 DOI: 10.1002/Jcp.22890  0.425
2012 Comley RA, Cervenka S, Palhagen SE, Panagiotidis G, Matthews JC, Lai RY, Halldin C, Farde L, Nichols TE, Whitcher BJ. A comparison of gray matter density in restless legs syndrome patients and matched controls using voxel-based morphometry. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 22: 28-32. PMID 21091816 DOI: 10.1111/J.1552-6569.2010.00536.X  0.59
2012 Guterstam J, Jayaram-Lindstrom N, Cervenka S, Halldin C, Farde L, Frost J, Franck J. P.3.004 Amphetamine-opioid interactions in the human brain reward system – a PET study using [11C]carfentanil European Neuropsychopharmacology. 22: S55. DOI: 10.1016/S0924-977X(12)70057-3  0.641
2012 Chen K, Langbaum J, Fleisher A, Roontiva A, Liu X, Thiyyagura P, Bandy D, Richter N, Jakimovich L, Prouty A, Cselenyi Z, Farde L, Budd S, Reiman E. IC-P-011: Amyloid PET imaging using AZD4694 and unusually brief radiotracer uptake and scanning periods Alzheimer's & Dementia. 8: P14-P14. DOI: 10.1016/j.jalz.2012.05.043  0.302
2011 Goodwin RJ, Mackay CL, Nilsson A, Harrison DJ, Farde L, Andren PE, Iverson SL. Qualitative and quantitative MALDI imaging of the positron emission tomography ligands raclopride (a D2 dopamine antagonist) and SCH 23390 (a D1 dopamine antagonist) in rat brain tissue sections using a solvent-free dry matrix application method. Analytical Chemistry. 83: 9694-701. PMID 22077717 DOI: 10.1021/ac202630t  0.316
2011 Karlsson S, Rieckmann A, Karlsson P, Farde L, Nyberg L, Bäckman L. Relationship of dopamine D1 receptor binding in striatal and extrastriatal regions to cognitive functioning in healthy humans. Neuroimage. 57: 346-51. PMID 21549202 DOI: 10.1016/J.Neuroimage.2011.04.047  0.47
2011 Nord M, Nyberg S, Brogren J, Jucaite A, Halldin C, Farde L. Comparison of Dâ‚‚ dopamine receptor occupancy after oral administration of quetiapine fumarate immediate-release and extended-release formulations in healthy subjects. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 1357-66. PMID 21477416 DOI: 10.1017/S1461145711000514  0.475
2011 Takano A, Nag S, Gulyás B, Halldin C, Farde L. NET occupancy by clomipramine and its active metabolite, desmethylclomipramine, in non-human primates in vivo. Psychopharmacology. 216: 279-86. PMID 21336575 DOI: 10.1007/S00213-011-2212-9  0.693
2011 Andersson JD, Pierson ME, Finnema SJ, Gulyás B, Heys R, Elmore CS, Farde L, Halldin C. Development of a PET radioligand for the central 5-HT1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds. Nuclear Medicine and Biology. 38: 261-72. PMID 21315282 DOI: 10.1016/J.Nucmedbio.2010.08.006  0.729
2011 Rieckmann A, Karlsson S, Karlsson P, Brehmer Y, Fischer H, Farde L, Nyberg L, Bäckman L. Dopamine D1 receptor associations within and between dopaminergic pathways in younger and elderly adults: links to cognitive performance. Cerebral Cortex (New York, N.Y. : 1991). 21: 2023-32. PMID 21258043 DOI: 10.1093/Cercor/Bhq266  0.43
2011 Varnäs K, Nyberg S, Karlsson P, Pierson ME, KÃ¥gedal M, Cselényi Z, McCarthy D, Xiao A, Zhang M, Halldin C, Farde L. Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369. Psychopharmacology. 213: 533-45. PMID 21234549 DOI: 10.1007/S00213-011-2165-Z  0.487
2011 Nord M, Farde L. Antipsychotic occupancy of dopamine receptors in schizophrenia. Cns Neuroscience & Therapeutics. 17: 97-103. PMID 21143431 DOI: 10.1111/j.1755-5949.2010.00222.x  0.482
2011 Esmaeilzadeh M, Farde L, Karlsson P, Varrone A, Halldin C, Waters S, Tedroff J. Extrastriatal dopamine D(2) receptor binding in Huntington's disease. Human Brain Mapping. 32: 1626-36. PMID 20886576 DOI: 10.1002/Hbm.21134  0.521
2011 Kodaka F, Ito H, Takano H, Takahashi H, Arakawa R, Miyoshi M, Okumura M, Otsuka T, Nakayama K, Halldin C, Farde L, Suhara T. Effect of risperidone on high-affinity state of dopamine D2 receptors: a PET study with agonist ligand [11C](R)-2-CH3O-N-n-propylnorapomorphine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 83-9. PMID 20860881 DOI: 10.1017/S1461145710001148  0.524
2011 Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, Andersson J, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L. Quantitative analysis of [11C]AZ10419369 binding to 5-HT1B receptors in human brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 113-23. PMID 20424633 DOI: 10.1038/Jcbfm.2010.55  0.457
2011 Bäckman L, Karlsson S, Fischer H, Karlsson P, Brehmer Y, Rieckmann A, MacDonald SW, Farde L, Nyberg L. Dopamine D(1) receptors and age differences in brain activation during working memory. Neurobiology of Aging. 32: 1849-56. PMID 19962789 DOI: 10.1016/J.Neurobiolaging.2009.10.018  0.411
2010 Andersson JD, Varnäs K, Cselényi Z, Gulyás B, Wensbo D, Finnema SJ, Swahn BM, Svensson S, Nyberg S, Farde L, Halldin C. Radiosynthesis of the candidate beta-amyloid radioligand [(11)C]AZD2184: Positron emission tomography examination and metabolite analysis in cynomolgus monkeys. Synapse (New York, N.Y.). 64: 733-41. PMID 20698029 DOI: 10.1002/Syn.20782  0.721
2010 de Manzano O, Cervenka S, Karabanov A, Farde L, Ullén F. Thinking outside a less intact box: thalamic dopamine D2 receptor densities are negatively related to psychometric creativity in healthy individuals. Plos One. 5: e10670. PMID 20498850 DOI: 10.1371/Journal.Pone.0010670  0.675
2010 Juréus A, Swahn BM, Sandell J, Jeppsson F, Johnson AE, Johnström P, Neelissen JA, Sunnemark D, Farde L, Svensson SP. Characterization of AZD4694, a novel fluorinated Abeta plaque neuroimaging PET radioligand. Journal of Neurochemistry. 114: 784-94. PMID 20477945 DOI: 10.1111/j.1471-4159.2010.06812.x  0.406
2010 Karabanov A, Cervenka S, de Manzano O, Forssberg H, Farde L, Ullén F. Dopamine D2 receptor density in the limbic striatum is related to implicit but not explicit movement sequence learning. Proceedings of the National Academy of Sciences of the United States of America. 107: 7574-9. PMID 20368439 DOI: 10.1073/Pnas.0911805107  0.582
2010 Finnema SJ, Varrone A, Hwang TJ, Gulyás B, Pierson ME, Halldin C, Farde L. Fenfluramine-induced serotonin release decreases [11C]AZ10419369 binding to 5-HT1B-receptors in the primate brain. Synapse (New York, N.Y.). 64: 573-7. PMID 20222157 DOI: 10.1002/Syn.20780  0.703
2010 Cervenka S, Varrone A, Fransén E, Halldin C, Farde L. PET studies of D2-receptor binding in striatal and extrastriatal brain regions: Biochemical support in vivo for separate dopaminergic systems in humans. Synapse (New York, N.Y.). 64: 478-85. PMID 20175222 DOI: 10.1002/Syn.20765  0.728
2010 Fischer H, Nyberg L, Karlsson S, Karlsson P, Brehmer Y, Rieckmann A, MacDonald SW, Farde L, Bäckman L. Simulating neurocognitive aging: effects of a dopaminergic antagonist on brain activity during working memory. Biological Psychiatry. 67: 575-80. PMID 20138255 DOI: 10.1016/J.Biopsych.2009.12.013  0.402
2010 Jucaite A, Forssberg H, Karlsson P, Halldin C, Farde L. Age-related reduction in dopamine D1 receptors in the human brain: from late childhood to adulthood, a positron emission tomography study. Neuroscience. 167: 104-10. PMID 20109534 DOI: 10.1016/J.Neuroscience.2010.01.034  0.494
2010 Cervenka S, Gustavsson JP, Halldin C, Farde L. Association between striatal and extrastriatal dopamine D2-receptor binding and social desirability. Neuroimage. 50: 323-8. PMID 20004254 DOI: 10.1016/J.Neuroimage.2009.12.006  0.674
2010 Finnema S, Varrone A, Hwang T, Farde L, Halldin C. P.1.e.021 In vivo assessment of changes in serotonin release in the non-human primate brain using PET and [11C]AZ10419369 European Neuropsychopharmacology. 20: S299-S300. DOI: 10.1016/S0924-977X(10)70399-0  0.411
2010 Cselényi Z, Jönhagen ME, Forsberg A, Halldin C, Julin P, Schou M, Johnström P, Varnäs K, Svensson S, Farde L. Quantification and wavelet-aided parametric imaging of cerebral amyloid using the HRRT PET-system and [18F]AZD4694 Neuroimage. 52: S142. DOI: 10.1016/J.Neuroimage.2010.04.116  0.319
2010 Andersson J, Seneca N, Truong P, Wensbo D, McLeod D, Raboisson P, Farde L, Halldin C. The novel mGluR5 radioligand [11C]AZ11696415: Palladium mediated 11C-cyanation and initial in vivo characterization in the cynomolgus monkey brain using positron emission tomography (PET) Neuroimage. 52: S122. DOI: 10.1016/J.Neuroimage.2010.04.100  0.466
2010 Kodaka F, Ito H, Takano H, Takahashi H, Arakawa R, Fujie S, Sasaki T, Nakayama K, Halldin C, Farde L, Suhara T. Regional distribution of high and low affinity states of dopamine D2/3 receptor binding in humans: A PET study using [11C]MNPA and [11C]raclopride Neuroimage. 52: S95. DOI: 10.1016/J.Neuroimage.2010.04.076  0.543
2010 Finnema S, Varnäs K, Stepanov V, Varrone A, Gulyás B, Arponen E, Helin S, Solin O, Haaparanta M, Sallinen J, Ingman K, Scheinin M, Farde L, Halldin C. Amphetamine decreases binding of the novel alpha2C-adrenoreceptor radioligand [11C]ORM-13070 in monkey brain Neuroimage. 52: S61-S62. DOI: 10.1016/J.Neuroimage.2010.04.047  0.706
2010 Finnema S, Varrone A, Hwang T, Farde L, Halldin C. Confirmation of fenfluramine effect on 5-HT1B binding of [11C]AZ10419369 using an equilibrium approach Neuroimage. 52: S55. DOI: 10.1016/J.Neuroimage.2010.04.042  0.346
2009 Karlsson S, Nyberg L, Karlsson P, Fischer H, Thilers P, Macdonald S, Brehmer Y, Rieckmann A, Halldin C, Farde L, Bäckman L. Modulation of striatal dopamine D1 binding by cognitive processing. Neuroimage. 48: 398-404. PMID 19539768 DOI: 10.1016/J.Neuroimage.2009.06.030  0.421
2009 MacDonald SW, Cervenka S, Farde L, Nyberg L, Bäckman L. Extrastriatal dopamine D2 receptor binding modulates intraindividual variability in episodic recognition and executive functioning. Neuropsychologia. 47: 2299-304. PMID 19524093 DOI: 10.1016/J.Neuropsychologia.2009.01.016  0.609
2009 Henningsson S, Borg J, Lundberg J, Bah J, Lindström M, Ryding E, Jovanovic H, Saijo T, Inoue M, Rosén I, Träskman-Bendz L, Farde L, Eriksson E. Genetic variation in brain-derived neurotrophic factor is associated with serotonin transporter but not serotonin-1A receptor availability in men. Biological Psychiatry. 66: 477-85. PMID 19500776 DOI: 10.1016/J.Biopsych.2009.04.009  0.45
2009 Nyberg S, Jönhagen ME, Cselényi Z, Halldin C, Julin P, Olsson H, Freund-Levi Y, Andersson J, Varnäs K, Svensson S, Farde L. Detection of amyloid in Alzheimer's disease with positron emission tomography using [11C]AZD2184. European Journal of Nuclear Medicine and Molecular Imaging. 36: 1859-63. PMID 19495746 DOI: 10.1007/S00259-009-1182-1  0.414
2009 Varrone A, Sjöholm N, Eriksson L, Gulyás B, Halldin C, Farde L. Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT. European Journal of Nuclear Medicine and Molecular Imaging. 36: 1639-50. PMID 19437012 DOI: 10.1007/S00259-009-1156-3  0.72
2009 Otsuka T, Ito H, Halldin C, Takahashi H, Takano H, Arakawa R, Okumura M, Kodaka F, Miyoshi M, Sekine M, Seki C, Nakao R, Suzuki K, Finnema S, Hirayasu Y, ... ... Farde L, et al. Quantitative PET analysis of the dopamine D2 receptor agonist radioligand 11C-(R)-2-CH3O-N-n-propylnorapomorphine in the human brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 703-10. PMID 19372485 DOI: 10.2967/Jnumed.108.058503  0.545
2009 Larsson M, Farde L, Hummel T, Witt M, Lindroth NE, Bäckman L. Age-related loss of olfactory sensitivity: association to dopamine transporter binding in putamen. Neuroscience. 161: 422-6. PMID 19348872 DOI: 10.1016/J.Neuroscience.2009.03.074  0.352
2009 McNab F, Varrone A, Farde L, Jucaite A, Bystritsky P, Forssberg H, Klingberg T. Changes in cortical dopamine D1 receptor binding associated with cognitive training. Science (New York, N.Y.). 323: 800-2. PMID 19197069 DOI: 10.1126/Science.1166102  0.416
2009 Finnema SJ, Halldin C, Bang-Andersen B, Gulyás B, Bundgaard C, Wikström HV, Farde L. Dopamine D(2/3) receptor occupancy of apomorphine in the nonhuman primate brain--a comparative PET study with [11C]raclopride and [11C]MNPA. Synapse (New York, N.Y.). 63: 378-89. PMID 19173265 DOI: 10.1002/Syn.20615  0.756
2009 Johnson AE, Jeppsson F, Sandell J, Wensbo D, Neelissen JA, Juréus A, Ström P, Norman H, Farde L, Svensson SP. AZD2184: a radioligand for sensitive detection of beta-amyloid deposits. Journal of Neurochemistry. 108: 1177-86. PMID 19141073 DOI: 10.1111/j.1471-4159.2008.05861.x  0.366
2009 Odano I, Halldin C, Karlsson P, Varrone A, Airaksinen AJ, Krasikova RN, Farde L. [18F]flumazenil binding to central benzodiazepine receptor studies by PET--quantitative analysis and comparisons with [11C]flumazenil. Neuroimage. 45: 891-902. PMID 19136064 DOI: 10.1016/J.Neuroimage.2008.12.005  0.458
2009 Borg J, Henningsson S, Saijo T, Inoue M, Bah J, Westberg L, Lundberg J, Jovanovic H, Andrée B, Nordstrom AL, Halldin C, Eriksson E, Farde L. Serotonin transporter genotype is associated with cognitive performance but not regional 5-HT1A receptor binding in humans. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 783-92. PMID 19126263 DOI: 10.1017/S1461145708009759  0.425
2009 Schou M, Zoghbi SS, Shetty HU, Shchukin E, Liow JS, Hong J, Andrée BA, Gulyás B, Farde L, Innis RB, Pike VW, Halldin C. Investigation of the metabolites of (S,S)-[(11)C]MeNER in humans, monkeys and rats. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 11: 23-30. PMID 18800204 DOI: 10.1007/S11307-008-0175-Y  0.682
2009 Cervenka S, Halldin C, Farde L. P.1.06 Limbic dopamine D2-receptor binding and social desirability European Neuropsychopharmacology. 19: S7-S8. DOI: 10.1016/S0924-977X(09)70009-4  0.658
2009 Sundgren-Andersson AK, Svensson SP, Swahn B, Juréus A, Sandell J, Johnson AE, Jeppsson F, Neelissen JA, Halldin C, Johnström P, Schou M, Cselényi Z, Farde L. P2-023: AZD4694: Fluorinated Positron Emission Tomography (PET) radioligand for detection of β-amyloid deposits Alzheimer's & Dementia. 5: P267-P268. DOI: 10.1016/J.Jalz.2009.04.332  0.33
2008 Airaksinen AJ, Nag S, Finnema SJ, Mukherjee J, Chattopadhyay S, Gulyás B, Farde L, Halldin C. [11C]cyclopropyl-FLB 457: a PET radioligand for low densities of dopamine D2 receptors. Bioorganic & Medicinal Chemistry. 16: 6467-73. PMID 18534857 DOI: 10.1016/J.Bmc.2008.05.039  0.764
2008 Pierson ME, Andersson J, Nyberg S, McCarthy DJ, Finnema SJ, Varnäs K, Takano A, Karlsson P, Gulyás B, Medd AM, Lee CM, Powell ME, Heys JR, Potts W, Seneca N, ... ... Farde L, et al. [11C]AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain. Neuroimage. 41: 1075-85. PMID 18434202 DOI: 10.1016/J.Neuroimage.2008.02.063  0.732
2008 Cervenka S, Bäckman L, Cselényi Z, Halldin C, Farde L. Associations between dopamine D2-receptor binding and cognitive performance indicate functional compartmentalization of the human striatum. Neuroimage. 40: 1287-95. PMID 18296072 DOI: 10.1016/J.Neuroimage.2007.12.063  0.675
2008 Cervenka S, Halldin C, Farde L. Age-related diurnal effect on D2 receptor binding: a preliminary PET study. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 671-8. PMID 18184446 DOI: 10.1017/S1461145707008358  0.699
2008 Hirvonen J, Johansson J, Teräs M, Oikonen V, Lumme V, Virsu P, Roivainen A, NÃ¥gren K, Halldin C, Farde L, Hietala J. Measurement of striatal and extrastriatal dopamine transporter binding with high-resolution PET and [11C]PE2I: quantitative modeling and test-retest reproducibility. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1059-69. PMID 18183028 DOI: 10.1038/Sj.Jcbfm.9600607  0.512
2008 Nordstrom AL, Mansson M, Jovanovic H, Karlsson P, Halldin C, Farde L, Vanover KE, Hacksell U, Brann MR, Davis RE, Weiner DM. PET analysis of the 5-HT2A receptor inverse agonist ACP-103 in human brain. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 163-71. PMID 17708779 DOI: 10.1017/S1461145707007869  0.466
2008 Nyberg S, Takano A, Jucaite A, Karlsson P, McCarthy D, Kågedal M, Eriksson H, Lee C, Halldin C, Farde L. P.1.e.019 PET-measured occupancy of the norepinephrene transporter by extended release quetiapine fumarate (quetiapine XR) in brains of healthy subjects European Neuropsychopharmacology. 18: S270. DOI: 10.1016/S0924-977X(08)70352-3  0.361
2008 Jovanovic H, Andersson E, Karlsson P, Halldin C, Nordstöm A, Åsberg M, Farde L. P.3.24 Lower 5-HT1A receptor binding in patients with borderline personality disorder: a PET study using [11C]WAY100635 European Neuropsychopharmacology. 18: s82-s83. DOI: 10.1016/S0924-977X(08)70095-6  0.438
2008 Borg J, Lundberg J, Andrée B, Kizling I, Halldin C, Farde L. P.3.02 Molecular imaging of the 5-HT1A receptor and 5-HTT in relation to cognitive functions in man European Neuropsychopharmacology. 18: s64. DOI: 10.1016/S0924-977X(08)70073-7  0.305
2008 Finnema SJ, Bang-Andersen B, Gulyás B, Bundgaard C, Wikström H, Halldin C, Farde L. Dopamine D2/3 receptor occupancy of apomorphine in the non-human primate brain does not support the existence of two affinity states in vivo Neuroimage. 41: T38. DOI: 10.1016/j.neuroimage.2008.04.212  0.489
2008 Otsuka T, Ito H, Takahashi H, Takano H, Arakawa R, Okumura M, Kodaka F, Miyoshi M, Sekine M, Seki C, Suhara T, Halldin C, Farde L. Quantitative analysis of dopamine D2 receptor binding in human brain using PET with an agonist radioligand [11C]MNPA Neuroimage. 41: T134. DOI: 10.1016/J.Neuroimage.2008.04.102  0.591
2008 Steiger C, Finnema S, Wikström H, Gulyás B, Nakao R, Suzuki K, Farde L, Halldin C. Radiosynthesis of [11C]MNPA from the precursor (R)-(−)-2-hydroxy-10,11-acetonide-NPA and a preliminary test–retest PET analysis in monkey brain Neuroimage. 41: T102. DOI: 10.1016/j.neuroimage.2008.04.071  0.688
2008 Varrone A, Sjoholm N, Gulyas B, Halldin C, Farde L. Advancement in PET quantification using 3D-OP-OSEM PSF reconstruction with the HRRT Neuroimage. 41: T85. DOI: 10.1016/J.Neuroimage.2008.04.054  0.667
2008 Odano I, Sakaguchi K, Hosoya T, Varrone A, Savic I, Halldin C, Farde L. Automated system for parametric image analysis in neuroreceptor binding studies with PET Neuroimage. 41: T77. DOI: 10.1016/J.Neuroimage.2008.04.047  0.376
2007 Lundberg J, Borg J, Halldin C, Farde L. A PET study on regional coexpression of 5-HT1A receptors and 5-HTT in the human brain. Psychopharmacology. 195: 425-33. PMID 17874074 DOI: 10.1007/S00213-007-0928-3  0.484
2007 Lundberg J, Christophersen JS, Petersen KB, Loft H, Halldin C, Farde L. PET measurement of serotonin transporter occupancy: a comparison of escitalopram and citalopram. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 777-85. PMID 17201996 DOI: 10.1017/S1461145706007486  0.403
2007 Schou M, Pike VW, Sóvágó J, Gulyás B, Gallagher PT, Dobson DR, Walter MW, Rudyk H, Farde L, Halldin C. Synthesis of 11C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET. Bioorganic & Medicinal Chemistry. 15: 616-25. PMID 17123820 DOI: 10.1016/J.Bmc.2006.10.065  0.722
2007 Montgomery AJ, Asselin MC, Farde L, Grasby PM. Measurement of methylphenidate-induced change in extrastriatal dopamine concentration using [11C]FLB 457 PET. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 369-77. PMID 16685253 DOI: 10.1038/sj.jcbfm.9600339  0.527
2007 Karlsson P, Hargarter L, Dencker E, Nyberg S, Mannaert E, Boom S, Talluri K, Rossenu S, Eriksson B, Eerdekens M, Farde L. Pharmacokinetics and dopamine d2 and serotonin 5-ht2a receptor occupancy of paliperidone in healthy subjects: two open-label, single-dose studies (PAL-115) Pharmacopsychiatry. 40. DOI: 10.1055/S-2007-991781  0.327
2007 Nyberg S, Takano A, Grimm S, Gulyas B, McCarthy D, Lee C, Goldstein J, Halldin C, Farde L. P.1.c.022 PET-measured D2, 5-HT2, and norepinephrine transporter (NET) occupancy by quetiapine and N-desalkyl-quetiapine in non-human primates European Neuropsychopharmacology. 17: S254-S255. DOI: 10.1016/S0924-977X(07)70346-2  0.403
2007 Finnema S, Bang-Andersen B, Farde L, Jorgensen M, Gulyas B, Foged C, Wikstrom H, Halldin C. A preliminary characterisation of a dopamine d1 partial agonist radioligand for pet Journal of Cerebral Blood Flow and Metabolism. 27: PP04-02M.  0.379
2006 Talvik M, Nordström AL, Okubo Y, Olsson H, Borg J, Halldin C, Farde L. Dopamine D2 receptor binding in drug-naïve patients with schizophrenia examined with raclopride-C11 and positron emission tomography. Psychiatry Research. 148: 165-73. PMID 17095199 DOI: 10.1016/J.Pscychresns.2006.05.009  0.477
2006 Bäckman L, Nyberg L, Lindenberger U, Li SC, Farde L. The correlative triad among aging, dopamine, and cognition: current status and future prospects. Neuroscience and Biobehavioral Reviews. 30: 791-807. PMID 16901542 DOI: 10.1016/J.Neubiorev.2006.06.005  0.319
2006 Seneca N, Gulyás B, Varrone A, Schou M, Airaksinen A, Tauscher J, Vandenhende F, Kielbasa W, Farde L, Innis RB, Halldin C. Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2. Psychopharmacology. 188: 119-27. PMID 16896954 DOI: 10.1007/s00213-006-0483-3  0.705
2006 Cselényi Z, Olsson H, Halldin C, Gulyás B, Farde L. A comparison of recent parametric neuroreceptor mapping approaches based on measurements with the high affinity PET radioligands [11C]FLB 457 and [11C]WAY 100635. Neuroimage. 32: 1690-708. PMID 16859930 DOI: 10.1016/J.Neuroimage.2006.02.053  0.696
2006 Cervenka S, PÃ¥lhagen SE, Comley RA, Panagiotidis G, Cselényi Z, Matthews JC, Lai RY, Halldin C, Farde L. Support for dopaminergic hypoactivity in restless legs syndrome: a PET study on D2-receptor binding. Brain : a Journal of Neurology. 129: 2017-28. PMID 16816393 DOI: 10.1093/Brain/Awl163  0.7
2006 Lundberg J, Halldin C, Farde L. Measurement of serotonin transporter binding with PET and [11C]MADAM: a test-retest reproducibility study. Synapse (New York, N.Y.). 60: 256-63. PMID 16752362 DOI: 10.1002/Syn.20297  0.458
2006 Lee CM, Farde L. Using positron emission tomography to facilitate CNS drug development. Trends in Pharmacological Sciences. 27: 310-6. PMID 16678917 DOI: 10.1016/j.tips.2006.04.004  0.412
2006 Borg J, Andrée B, Lundberg J, Halldin C, Farde L. Search for correlations between serotonin 5-HT1A receptor expression and cognitive functions--a strategy in translational psychopharmacology. Psychopharmacology. 185: 389-94. PMID 16541245 DOI: 10.1007/S00213-006-0329-Z  0.391
2006 Jucaite A, Odano I, Olsson H, Pauli S, Halldin C, Farde L. Quantitative analyses of regional [11C]PE2I binding to the dopamine transporter in the human brain: a PET study. European Journal of Nuclear Medicine and Molecular Imaging. 33: 657-68. PMID 16514530 DOI: 10.1007/S00259-005-0027-9  0.509
2006 Seneca N, Finnema SJ, Farde L, Gulyás B, Wikström HV, Halldin C, Innis RB. Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride. Synapse (New York, N.Y.). 59: 260-9. PMID 16416444 DOI: 10.1002/Syn.20238  0.754
2006 Chou YH, Halldin C, Farde L. Clozapine binds preferentially to cortical D1-like dopamine receptors in the primate brain: a PET study. Psychopharmacology. 185: 29-35. PMID 16395606 DOI: 10.1007/S00213-005-0219-9  0.551
2006 Schou M, Sóvágó J, Pike VW, Gulyás B, Bøgesø KP, Farde L, Halldin C. Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 8: 1-8. PMID 16322935 DOI: 10.1007/S11307-005-0027-Y  0.724
2006 Bjerkenstedt L, Farde L, Terenius L, Edman G, Venizelos N, Wiesel FA. Support for limited brain availability of tyrosine in patients with schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 9: 247-55. PMID 15972118 DOI: 10.1017/S1461145705005638  0.348
2006 Finnema S, Bang-Andersen B, Farde L, Gulyás B, Wikström H, Halldin C. Dopamine D2/D3 receptor occupancy of apomorphine evaluated with the agonist radioligand [11C]MNPA and the antagonist radioligand [11C]Raclopride. A PET evaluation in the non-human primate brain Neuroimage. 31: T120. DOI: 10.1016/J.Neuroimage.2006.04.106  0.554
2006 Finnema S, Bang-Andersen B, Farde L, Jørgensen M, Gulyás B, Foged C, Wikström H, Halldin C. PET evaluation of the partial dopamine D1 receptor agonist radioligands R- and S-[11C]N-Methyl-NNC 01-0259 Neuroimage. 31: T114. DOI: 10.1016/J.Neuroimage.2006.04.100  0.493
2006 Odano I, Farde L, Savic I, Ciumas C, Krasikova R, Airaksinen A, Karlsson P, Pauli S, Halldin C. Comparisons of central benzodiazepine receptor mapping tracers [18F]Flumazenil and [11C]Flumazenil presentation Neuroimage. 31: T88. DOI: 10.1016/J.Neuroimage.2006.04.076  0.376
2006 Odano I, Jucaite A, Olsson H, Karlsson P, Pauli S, Halldin C, Farde L. Dopamine transporter binding corrected for tissue heterogeneity and partial volume effect using [11C]PE2I and PET Neuroimage. 31: T87. DOI: 10.1016/J.Neuroimage.2006.04.075  0.458
2006 Sovago J, Farde L, Cervenka S, Halldin C, Gulyas B. Increasing the accuracy of in vivo quantification of dopamine-D2/D3 receptor binding in the human brain by partial volume effect correction Neuroimage. 31: T85. DOI: 10.1016/J.Neuroimage.2006.04.073  0.799
2006 Schou M, Pike V, Sóvágó J, Gulyás B, Gallagher P, Dobson D, Walter M, Rudyk H, Farde L, Halldin C. Synthesis of 11C-labeled (S,S)-CFMME and (R)-OHDMI and their evaluation as candidate radioligands for imaging norepinephrine transporters with PET Neuroimage. 31: T48. DOI: 10.1016/j.neuroimage.2006.04.039  0.664
2006 KARLSSON P, DENCKER E, NYBERG S, MANNAERT E, BOOM S, TALLURI K, ROSSENU S, ERIKSSON B, EERDEKENS M, FARDE L. PIII-57Pharmacokinetics and dopamine D2 And serotonin 5-HT2A receptor occupancy of paliperidone in healthy subjects: Two open-label, single-dose studies Clinical Pharmacology & Therapeutics. 79: P74-P74. DOI: 10.1016/j.clpt.2005.12.265  0.327
2006 Schou M, Pike VW, Varrone A, Gulyás B, Farde L, Halldin C. Synthesis and PET evaluation of (R)-[S-methyl-11C] thionisoxetine, a candidate radioligand for imaging brain norepinephrine transporters Journal of Labelled Compounds and Radiopharmaceuticals. 49: 1007-1019. DOI: 10.1002/Jlcr.1128  0.69
2005 Lundberg J, Odano I, Olsson H, Halldin C, Farde L. Quantification of 11C-MADAM binding to the serotonin transporter in the human brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 46: 1505-15. PMID 16157534  0.333
2005 Sóvágó J, Farde L, Halldin C, Schukin E, Schou M, Laszlovszky I, Kiss B, Gulyás B. Lack of effect of reserpine-induced dopamine depletion on the binding of the dopamine-D3 selective radioligand, [11C]RGH-1756. Brain Research Bulletin. 67: 219-24. PMID 16144658 DOI: 10.1016/J.Brainresbull.2005.06.034  0.774
2005 Schou M, Halldin C, Pike VW, Mozley PD, Dobson D, Innis RB, Farde L, Hall H. Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 15: 517-20. PMID 16139169 DOI: 10.1016/J.Euroneuro.2005.01.007  0.428
2005 Halldin C, Lundberg J, Sóvágó J, Gulyás B, Guilloteau D, Vercouillie J, Emond P, Chalon S, Tarkiainen J, Hiltunen J, Farde L. [(11)C]MADAM, a new serotonin transporter radioligand characterized in the monkey brain by PET. Synapse (New York, N.Y.). 58: 173-83. PMID 16138320 DOI: 10.1002/Syn.20189  0.729
2005 Meschaks A, Lindstrom P, Halldin C, Farde L, Savic I. Regional reductions in serotonin 1A receptor binding in juvenile myoclonic epilepsy. Archives of Neurology. 62: 946-50. PMID 15956165 DOI: 10.1001/Archneur.62.6.946  0.394
2005 McCarron JA, Marchais-Oberwinkler S, Pike VW, Tarkiainen J, Halldin C, Sóvagó J, Gulyas B, Wikström HV, Farde L. Two C-methyl derivatives of [11C]WAY-100635--effects of an amido alpha-methyl group on metabolism and brain 5-HT1A receptor radioligand behavior in monkey. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 7: 209-19. PMID 15912425 DOI: 10.1007/S11307-005-4127-5  0.73
2005 Finnema SJ, Seneca N, Farde L, Shchukin E, Sóvágó J, Gulyás B, Wikström HV, Innis RB, Neumeyer JL, Halldin C. A preliminary PET evaluation of the new dopamine D2 receptor agonist [11C]MNPA in cynomolgus monkey. Nuclear Medicine and Biology. 32: 353-60. PMID 15878504 DOI: 10.1016/J.Nucmedbio.2005.01.007  0.727
2005 Gulyás B, Halldin C, Vas A, Banati RB, Shchukin E, Finnema S, Tarkainen J, Tihanyi K, Szilágyi G, Farde L. [11C]vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies. Journal of the Neurological Sciences. 229: 219-23. PMID 15760643 DOI: 10.1016/J.Jns.2004.11.032  0.736
2005 Erixon-Lindroth N, Farde L, Wahlin TB, Sovago J, Halldin C, Bäckman L. The role of the striatal dopamine transporter in cognitive aging. Psychiatry Research. 138: 1-12. PMID 15708296 DOI: 10.1016/J.Pscychresns.2004.09.005  0.31
2005 Jucaite A, Fernell E, Halldin C, Forssberg H, Farde L. Reduced midbrain dopamine transporter binding in male adolescents with attention-deficit/hyperactivity disorder: association between striatal dopamine markers and motor hyperactivity. Biological Psychiatry. 57: 229-38. PMID 15691523 DOI: 10.1016/J.Biopsych.2004.11.009  0.406
2005 Marchais-Oberwinkler S, Nowicki B, Pike VW, Halldin C, Sandell J, Chou YH, Gulyas B, Brennum LT, Farde L, Wikström HV. N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists. Bioorganic & Medicinal Chemistry. 13: 883-93. PMID 15653354 DOI: 10.1016/J.Bmc.2004.10.033  0.688
2005 Olsson H, Farde L. Half-life of receptor occupancy--a meaningless concept. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 8: 141-2. PMID 15482631 DOI: 10.1017/S1461145704004766  0.355
2005 Seneca N, Finnema S, Ichise M, Gulyas B, Wikstrom H, Innis RB, Farde L, Halldin C. Effect of amphetamine on dopamine D2 receptor binding in the primate brain with the agonist ligand [11C]MNPA Journal of Cerebral Blood Flow & Metabolism. 25: S646-S646. DOI: 10.1038/Sj.Jcbfm.9591524.0646  0.751
2004 Halldin C, Gulyás B, Farde L. PET for drug development. Ernst Schering Research Foundation Workshop. 95-109. PMID 15248518  0.611
2004 Cselényi Z, Lundberg J, Halldin C, Farde L, Gulyás B. Joint explorative analysis of neuroreceptor subsystems in the human brain: application to receptor-transporter correlation using PET data. Neurochemistry International. 45: 773-81. PMID 15234122 DOI: 10.1016/J.Neuint.2003.12.005  0.707
2004 Sóvágó J, Farde L, Halldin C, Langer O, Laszlovszky I, Kiss B, Gulyás B. Positron emission tomographic evaluation of the putative dopamine-D3 receptor ligand, [11C]RGH-1756 in the monkey brain. Neurochemistry International. 45: 609-17. PMID 15234102 DOI: 10.1016/J.Neuint.2004.04.004  0.779
2004 Olsson H, Halldin C, Farde L. Differentiation of extrastriatal dopamine D2 receptor density and affinity in the human brain using PET. Neuroimage. 22: 794-803. PMID 15193608 DOI: 10.1016/J.Neuroimage.2004.02.002  0.521
2004 Schou M, Halldin C, Sóvágó J, Pike VW, Hall H, Gulyás B, Mozley PD, Dobson D, Shchukin E, Innis RB, Farde L. PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain. Synapse (New York, N.Y.). 53: 57-67. PMID 15170818 DOI: 10.1002/Syn.20031  0.676
2004 Yasuno F, Suhara T, Okubo Y, Sudo Y, Inoue M, Ichimiya T, Takano A, Nakayama K, Halldin C, Farde L. Low dopamine d(2) receptor binding in subregions of the thalamus in schizophrenia. The American Journal of Psychiatry. 161: 1016-22. PMID 15169689 DOI: 10.1176/Appi.Ajp.161.6.1016  0.455
2004 Savic I, Lindström P, Gulyás B, Halldin C, Andrée B, Farde L. Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy. Neurology. 62: 1343-51. PMID 15111672 DOI: 10.1212/01.Wnl.0000123696.98166.Af  0.661
2004 Damberg M, BerggÃ¥rd C, Farde L, Sedvall GC, Jönsson EG. Transcription factor AP-2beta genotype, striatal dopamine D2 receptor density and cerebrospinal fluid monoamine metabolite concentrations in humans. Journal of Neural Transmission (Vienna, Austria : 1996). 111: 537-45. PMID 15057523 DOI: 10.1007/s00702-003-0097-4  0.549
2004 Balle T, Halldin C, Andersen L, Hjorth Alifrangis L, Badolo L, Gjervig Jensen K, Chou YW, Andersen K, Perregaard J, Farde L. New alpha(1)-adrenoceptor antagonists derived from the antipsychotic sertindole - carbon-11 labelling and pet examination of brain uptake in the cynomolgus monkey. Nuclear Medicine and Biology. 31: 327-36. PMID 15028245 DOI: 10.1016/J.Nucmedbio.2003.08.012  0.465
2004 McCarron JA, Pike VW, Halldin C, Sandell J, Sóvágó J, Gulyas B, Cselényi Z, Wikström HV, Marchais-Oberwinkler S, Nowicki B, Dollé F, Farde L. The pyridinyl-6 position of WAY-100635 as a site for radiofluorination--effect on 5-HT1A receptor radioligand behavior in vivo. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 6: 17-26. PMID 15018825 DOI: 10.1016/J.Mibio.2003.12.001  0.691
2004 Talvik M, Nordström AL, Larsen NE, Jucaite A, Cervenka S, Halldin C, Farde L. A cross-validation study on the relationship between central D2 receptor occupancy and serum perphenazine concentration. Psychopharmacology. 175: 148-53. PMID 15007534 DOI: 10.1007/S00213-004-1802-1  0.657
2003 Talvik M, Nordström AL, Olsson H, Halldin C, Farde L. Decreased thalamic D2/D3 receptor binding in drug-naive patients with schizophrenia: a PET study with [11C]FLB 457. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 6: 361-70. PMID 14604451 DOI: 10.1017/S1461145703003699  0.461
2003 Borg J, Andrée B, Soderstrom H, Farde L. The serotonin system and spiritual experiences. The American Journal of Psychiatry. 160: 1965-9. PMID 14594742 DOI: 10.1176/appi.ajp.160.11.1965  0.381
2003 Pike VW, Halldin C, Nobuhara K, Hiltunen J, Mulligan RS, Swahn CG, Karlsson P, Olsson H, Hume SP, Hirani E, Whalley J, Pilowsky LS, Larsson S, Schnell PO, Ell PJ, ... Farde L, et al. Radioiodinated SB 207710 as a radioligand in vivo: imaging of brain 5-HT4 receptors with SPET. European Journal of Nuclear Medicine and Molecular Imaging. 30: 1520-8. PMID 14579092 DOI: 10.1007/S00259-003-1307-X  0.461
2003 Schou M, Halldin C, Sóvágó J, Pike VW, Gulyás B, Mozley PD, Johnson DP, Hall H, Innis RB, Farde L. Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand, (S,S)-[11C]MeNER. Nuclear Medicine and Biology. 30: 707-14. PMID 14499328 DOI: 10.1016/S0969-8051(03)00079-9  0.692
2003 Carmine A, Buervenich S, Galter D, Jönsson EG, Sedvall GC, Farde L, Gustavsson JP, Bergman H, Chowdari KV, Nimgaonkar VL, Anvret M, Sydow O, Olson L. NURR1 promoter polymorphisms: Parkinson's disease, schizophrenia, and personality traits. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 120: 51-7. PMID 12815740 DOI: 10.1002/Ajmg.B.20033  0.469
2003 Halldin C, Erixon-Lindroth N, Pauli S, Chou YH, Okubo Y, Karlsson P, Lundkvist C, Olsson H, Guilloteau D, Emond P, Farde L. [(11)C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain. European Journal of Nuclear Medicine and Molecular Imaging. 30: 1220-30. PMID 12811422 DOI: 10.1007/S00259-003-1212-3  0.5
2003 Jönsson EG, Cichon S, Gustavsson JP, Grünhage F, Forslund K, Mattila-Evenden M, Rylander G, Asberg M, Farde L, Propping P, Nöthen MM. Association between a promoter dopamine D2 receptor gene variant and the personality trait detachment. Biological Psychiatry. 53: 577-84. PMID 12679235 DOI: 10.1016/S0006-3223(02)01732-8  0.386
2003 Andrée B, Hedman A, Thorberg SO, Nilsson D, Halldin C, Farde L. Positron emission tomographic analysis of dose-dependent NAD-299 binding to 5-hydroxytryptamine-1A receptors in the human brain. Psychopharmacology. 167: 37-45. PMID 12632244 DOI: 10.1007/S00213-002-1355-0  0.394
2003 Carmine A, Chheda MG, Jönsson EG, Sedvall GC, Farde L, Gustavsson JP, Bergman H, Anvret M, Buervenich S, Olson L. Two NOTCH4 polymorphisms and their relation to schizophrenia susceptibility and different personality traits. Psychiatric Genetics. 13: 23-8. PMID 12605097 DOI: 10.1097/01.ypg.0000056680.82896.22  0.506
2003 Chou YH, Halldin C, Farde L. Occupancy of 5-HT1A receptors by clozapine in the primate brain: a PET study. Psychopharmacology. 166: 234-40. PMID 12589516 DOI: 10.1007/S00213-002-1256-2  0.44
2003 Chalon S, Tarkiainen J, Garreau L, Hall H, Emond P, Vercouillie J, Farde L, Dasse P, Varnas K, Besnard JC, Halldin C, Guilloteau D. Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity. The Journal of Pharmacology and Experimental Therapeutics. 304: 81-7. PMID 12490578 DOI: 10.1124/Jpet.102.042226  0.378
2003 Talvik M, Nordström A, Olsson H, Halldin C, Farde L. P.2.115 PET examinations or thalamic D2 receptors in schizophrenic patients European Neuropsychopharmacology. 13: S330. DOI: 10.1016/S0924-977X(03)92068-2  0.446
2003 Farde L. S.06.03 Is dopamine a variable in PET-studies on drug induced receptor occupancy? European Neuropsychopharmacology. 13: S109-S110. DOI: 10.1016/S0924-977X(03)91622-1  0.346
2002 Vas A, Sóvágó J, Halldin C, Sandell J, Karlsson P, Kárpáti E, Kiss B, Cselényi Z, Farde L, Gulyás B. [Cerebral uptake and regional distribution of [11C]-vinpocetin after intravenous administration to healthy men: a PET study]. Orvosi Hetilap. 143: 2631-6. PMID 12532649  0.684
2002 Cselényi Z, Olsson H, Farde L, Gulyás B. Wavelet-aided parametric mapping of cerebral dopamine D2 receptors using the high affinity PET radioligand [11C]FLB 457. Neuroimage. 17: 47-60. PMID 12482067 DOI: 10.1006/nimg.2002.1152  0.694
2002 Gulyás B, Halldin C, Sandell J, Karlsson P, Sóvágó J, Kárpáti E, Kiss B, Vas A, Cselényi Z, Farde L. PET studies on the brain uptake and regional distribution of [11C]vinpocetine in human subjects. Acta Neurologica Scandinavica. 106: 325-32. PMID 12460136 DOI: 10.1034/J.1600-0404.2002.01302.X  0.701
2002 Gulyás B, Vas A, Halldin C, Sóvágó J, Sandell J, Olsson H, Fredriksson A, Stone-Elander S, Farde L. Cerebral uptake of [ethyl-11C]vinpocetine and 1-[11C]ethanol in cynomolgous monkeys: a comparative preclinical PET study. Nuclear Medicine and Biology. 29: 753-9. PMID 12381455 DOI: 10.1016/S0969-8051(02)00319-0  0.673
2002 Sandell J, Halldin C, Sovago J, Chou YH, Gulyás B, Yu M, Emond P, Någren K, Guilloteau D, Farde L. PET examination of [(11)C]5-methyl-6-nitroquipazine, a radioligand for visualization of the serotonin transporter. Nuclear Medicine and Biology. 29: 651-6. PMID 12234589 DOI: 10.1016/S0969-8051(02)00318-9  0.715
2002 Gulyás B, Halldin C, Sóvágó J, Sandell J, Cselényi Z, Vas A, Kiss B, Kárpáti E, Farde L. Drug distribution in man: a positron emission tomography study after oral administration of the labelled neuroprotective drug vinpocetine. European Journal of Nuclear Medicine and Molecular Imaging. 29: 1031-8. PMID 12173017 DOI: 10.1007/S00259-002-0823-4  0.679
2002 Nyberg S, Olsson H, Nilsson U, Maehlum E, Halldin C, Farde L. Low striatal and extra-striatal D2 receptor occupancy during treatment with the atypical antipsychotic sertindole. Psychopharmacology. 162: 37-41. PMID 12107615 DOI: 10.1007/S00213-002-1083-5  0.509
2002 Hall H, Varnäs K, Sandell J, Halldin C, Farde L, Vas A, Kárpáti E, Gulyás B. Autoradiographic evaluation of [11C]vinpocetine binding in the human postmortem brain. Acta Biologica Hungarica. 53: 59-66. PMID 12064779 DOI: 10.1556/ABiol.53.2002.1-2.7  0.712
2002 Karlsson P, Farde L, Halldin C, Sedvall G. PET study of D(1) dopamine receptor binding in neuroleptic-naive patients with schizophrenia. The American Journal of Psychiatry. 159: 761-7. PMID 11986129 DOI: 10.1176/Appi.Ajp.159.5.761  0.658
2002 Andrée B, Halldin C, Pike VW, Gunn RN, Olsson H, Farde L. The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 43: 292-303. PMID 11884487  0.378
2002 Sandell J, Halldin C, Chou YH, Swahn CG, Thorberg SO, Farde L. PET-examination and metabolite evaluation in monkey of [(11)C]NAD-299, a radioligand for visualisation of the 5-HT(1A) receptor. Nuclear Medicine and Biology. 29: 39-45. PMID 11786274 DOI: 10.1016/S0969-8051(01)00272-4  0.45
2002 Suhara T, Okubo Y, Yasuno F, Sudo Y, Inoue M, Ichimiya T, Nakashima Y, Nakayama K, Tanada S, Suzuki K, Halldin C, Farde L. Decreased dopamine D2 receptor binding in the anterior cingulate cortex in schizophrenia. Archives of General Psychiatry. 59: 25-30. PMID 11779278 DOI: 10.1001/Archpsyc.59.1.25  0.421
2002 Farde L. PET imaging of brain neurotransmission European Psychiatry. 17. DOI: 10.1016/S0924-9338(02)85016-7  0.392
2001 Halldin C, Gulyás B, Farde L. PET studies with carbon-11 radioligands in neuropsychopharmacological drug development. Current Pharmaceutical Design. 7: 1907-29. PMID 11772357 DOI: 10.2174/1381612013396871  0.677
2001 Sudo Y, Suhara T, Inoue M, Ito H, Suzuki K, Saijo T, Halldin C, Farde L. Reproducibility of [11 C]FLB 457 binding in extrastriatal regions. Nuclear Medicine Communications. 22: 1215-21. PMID 11606887 DOI: 10.1097/00006231-200111000-00008  0.418
2001 Olsson H, Farde L. Potentials and pitfalls using high affinity radioligands in PET and SPET determinations on regional drug induced D2 receptor occupancy--a simulation study based on experimental data. Neuroimage. 14: 936-45. PMID 11554812 DOI: 10.1006/nimg.2001.0879  0.509
2001 Bäckman L, Farde L. Dopamine and cognitive functioning: brain imaging findings in Huntington's disease and normal aging. Scandinavian Journal of Psychology. 42: 287-96. PMID 11501742 DOI: 10.1111/1467-9450.00238  0.315
2001 Halldin C, Gulyás B, Langer O, Farde L. Brain radioligands--state of the art and new trends. The Quarterly Journal of Nuclear Medicine : Official Publication of the Italian Association of Nuclear Medicine (Aimn) [and] the International Association of Radiopharmacology (Iar). 45: 139-52. PMID 11476163  0.71
2001 Talvik M, Nordström AL, Nyberg S, Olsson H, Halldin C, Farde L. No support for regional selectivity in clozapine-treated patients: a PET study with [(11)C]raclopride and [(11)C]FLB 457. The American Journal of Psychiatry. 158: 926-30. PMID 11384901 DOI: 10.1176/Appi.Ajp.158.6.926  0.532
2001 Sandell J, Halldin C, Pike VW, Chou YH, Varnäs K, Hall H, Marchais S, Nowicki B, Wikström HV, Swahn CG, Farde L. New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey. Nuclear Medicine and Biology. 28: 177-85. PMID 11295428 DOI: 10.1016/S0969-8051(00)00181-5  0.498
2001 Nobuhara K, Farde L, Halldin C, Karlsson P, Swahn CG, Olsson H, Bergström KA, Larsson SA, Schnell PO, McPherson DW, Savonen A, Hiltunen J, Sedvall G. SPET imaging of central muscarinic acetylcholine receptors with iodine-123 labelled E-IQNP and Z-IQNP. European Journal of Nuclear Medicine. 28: 13-24. PMID 11202446 DOI: 10.1007/S002590000390  0.535
2001 Ito H, Sudo Y, Suhara T, Okubo Y, Halldin C, Farde L. Error analysis for quantification of [(11)C]FLB 457 binding to extrastriatal D(2) dopamine receptors in the human brain. Neuroimage. 13: 531-9. PMID 11170818 DOI: 10.1006/Nimg.2000.0717  0.49
2001 Kaasinen V, NÃ¥gren K, Hietala J, Farde L, Rinne JO. Sex differences in extrastriatal dopamine d(2)-like receptors in the human brain. The American Journal of Psychiatry. 158: 308-11. PMID 11156817 DOI: 10.1176/appi.ajp.158.2.308  0.512
2001 Cselényi Z, Olsson H, Gulyás B, Halldin C, Farde L. Detailed mapping of dopamine D2 receptors in the human limbic system using FLB 457 binding analysis in wavelet space Neuroimage. 13: 1299. DOI: 10.1016/S1053-8119(01)92613-8  0.699
2001 Savic I, Gulyas B, Lindström P, Halldin C, Farde L. Mesial temporal lobe epilepsy is associated with limbic reductions in serotonin 5HT1A receptor binding Neuroimage. 13: 833. DOI: 10.1016/S1053-8119(01)92175-5  0.363
2001 Gulyás B, Halldin C, Sóvágó J, Sandell J, Cselényi Z, Karlsson P, Kárpáti E, Kiss B, Vas A, Farde L. A novel principle of radiotracer administration in human brain mapping: pet studies on brain uptake and distribution of orally and intravenously administered [11C]vinpocetine Neuroimage. 13: 12. DOI: 10.1016/S1053-8119(01)91355-2  0.695
2001 Sandell J, Yu M, Emond P, Gulyas B, Cselenyi Z, Sovago J, Garreau L, Hall H, Chalon S, Guilloteau D, Någren K, Farde L, Halldin C. Radiolabeling, preliminary biological evaluation and pet examination in monkey of 5-methyl-6-nitroquipazine - a potential serotonin transporter radioligand Journal of Labelled Compounds and Radiopharmaceuticals. 44: S170-S172. DOI: 10.1002/JLCR.2580440159  0.357
2001 Sandell J, Mccarron JA, Halldin C, Pike VW, Gulyas B, Cselenyi Z, Sovago J, Marchais S, Wikström HV, Farde L. [18F]6FPWAY - a prospective 5-HT1A receptor radioligand - radiolabeling and pet examination in monkey - comparison with [11C]6FPWAY Journal of Labelled Compounds and Radiopharmaceuticals. 44: S167-S169. DOI: 10.1002/Jlcr.2580440158  0.45
2001 Någren K, Halldin C, Pike VW, Allonen T, Hietala J, Swahn C, Andrée B, Farde L, Osman S, Grasby P. Radioactive metabolites of the 5-HT1A receptor pet radioligand, [carbonyl-11C]way-100635, measured in human plasma samples Journal of Labelled Compounds and Radiopharmaceuticals. 44: S472-S474. DOI: 10.1002/JLCR.25804401167  0.404
2000 Farde L, Ginovart N, Halldin C, Chou YH, Olsson H, Swahn CG. A PET study of The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 3: 203-214. PMID 11343597 DOI: 10.1017/S1461145700002030  0.484
2000 Langer O, Halldin C, Chou Y, Sandell J, Swahn C, Någren K, Perrone R, Berardi F, Leopoldo M, Farde L. Carbon-11 pb-12: an attempt to visualize the dopamine d(4) receptor in the primate brain with positron emission tomography. Nuclear Medicine and Biology. 27: 707-14. PMID 11150701 DOI: 10.1016/S0969-8051(00)00154-2  0.535
2000 Hall H, Farde L, Halldin C, Lundkvist C, Sedvall G. Autoradiographic localization of 5-HT(2A) receptors in the human brain using [(3)H]M100907 and [(11)C]M100907. Synapse (New York, N.Y.). 38: 421-31. PMID 11044889 DOI: 10.1002/1098-2396(20001215)38:4<421::Aid-Syn7>3.0.Co;2-X  0.567
2000 Chou YH, Halldin C, Farde L. Effect of amphetamine on extrastriatal D2 dopamine receptor binding in the primate brain: a PET study. Synapse (New York, N.Y.). 38: 138-43. PMID 11018787 DOI: 10.1002/1098-2396(200011)38:2<138::Aid-Syn4>3.0.Co;2-7  0.564
2000 Kaasinen V, Vilkman H, Hietala J, NÃ¥gren K, Helenius H, Olsson H, Farde L, Rinne J. Age-related dopamine D2/D3 receptor loss in extrastriatal regions of the human brain. Neurobiology of Aging. 21: 683-8. PMID 11016537 DOI: 10.1016/S0197-4580(00)00149-4  0.424
2000 Andrée B, Halldin C, Thorberg SO, Sandell J, Farde L. Use of PET and the radioligand [carbonyl-(11)C]WAY-100635 in psychotropic drug development. Nuclear Medicine and Biology. 27: 515-21. PMID 10962260 DOI: 10.1016/S0969-8051(00)00121-9  0.415
2000 Pike VW, Halldin C, Wikström H, Marchais S, McCarron JA, Sandell J, Nowicki B, Swahn CG, Osman S, Hume SP, Constantinou M, Andrée B, Farde L. Radioligands for the study of brain 5-HT(1A) receptors in vivo--development of some new analogues of way. Nuclear Medicine and Biology. 27: 449-55. PMID 10962249 DOI: 10.1016/S0969-8051(00)00110-4  0.468
2000 Talvik-Lotfi M, Nyberg S, Nordström AL, Ito H, Halldin C, Brunner F, Farde L. High 5HT2A receptor occupancy in M100907-treated schizophrenic patients. Psychopharmacology. 148: 400-3. PMID 10928313 DOI: 10.1007/S002130050069  0.346
2000 Nobuhara K, Halldin C, Hall H, Karlsson P, Farde L, Hiltunen J, McPherson DW, Savonen A, Bergström KA, Pauli S, Swahn CG, Larsson SA, Schnell PO, Sedvall G. Z-IQNP: a potential radioligand for SPECT imaging of muscarinic acetylcholine receptors in Alzheimer's disease. Psychopharmacology. 149: 45-55. PMID 10789882 DOI: 10.1007/S002139900356  0.584
2000 Bäckman L, Ginovart N, Dixon RA, Wahlin TB, Wahlin A, Halldin C, Farde L. Age-related cognitive deficits mediated by changes in the striatal dopamine system. The American Journal of Psychiatry. 157: 635-7. PMID 10739428 DOI: 10.1176/Ajp.157.4.635  0.353
2000 Farde L, Andrée B, Ginovart N, Halldin C, Thorberg S. PET-Determination of robalzotan (NAD-299) induced 5-HT(1A) receptor occupancy in the monkey brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 422-9. PMID 10700661 DOI: 10.1016/S0893-133X(99)00125-6  0.402
2000 Nyberg S, Farde L. Non-equipotent doses partly explain differences among antipsychotics - implications of PET studies. Psychopharmacology. 148: 22-3. PMID 10663413 DOI: 10.1007/S002130050020  0.314
2000 Langer O, Gulyás B, Sandell J, Laszlovszky I, Kiss B, Domány G, Ács T, Farde L, Halldin C. Radiochemical labelling of the dopamine D3 receptor ligand RGH-1756 Journal of Labelled Compounds and Radiopharmaceuticals. 43: 1069-1074. DOI: 10.1002/1099-1344(20001015)43:11<1069::Aid-Jlcr390>3.0.Co;2-N  0.761
2000 Sandell J, Halldin C, Helfenbein J, Chou YH, Vercouillie J, Emond P, Swahn CG, Guilloteau D, Farde L. Synthesis of two dopamine D4 receptor ligands: 11C labelled chromeno[3,4-c]pyridin-5-ones Journal of Labelled Compounds and Radiopharmaceuticals. 43: 989-996. DOI: 10.1002/1099-1344(200009)43:10<989::AID-JLCR384>3.0.CO;2-3  0.371
2000 Sandell J, Halldin C, Helfenbein J, Chou Y, Vercouillie J, Emond P, Swahn C, Guilloteau D, Farde L. Synthesis of [11C]2?-carbomethoxy-3?-(3?-iodo-4?-methyl, -ethyl and isopropyl phenyl)nortropane as potential radiotracers for examination of the serotonin transporter with positron emission tomography Journal of Labelled Compounds and Radiopharmaceuticals. 43: 1033-1046. DOI: 10.1002/1099-1344(200009)43:10<1033::Aid-Jlcr389>3.0.Co;2-5  0.41
2000 Karlsson P, Farde L, Halldin C. Circadian rhythm in central D1-like dopamine receptors examined by PET Neuroimage. 11: S41.  0.398
1999 Suhara T, Sudo Y, Okauchi T, Maeda J, Kawabe K, Suzuki K, Okubo Y, Nakashima Y, Ito H, Tanada S, Halldin C, Farde L. Extrastriatal dopamine D2 receptor density and affinity in the human brain measured by 3D PET. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 2: 73-82. PMID 11281973 DOI: 10.1017/S1461145799001431  0.537
1999 Okubo Y, Olsson H, Ito H, Lofti M, Suhara T, Halldin C, Farde L. PET mapping of extrastriatal D2-like dopamine receptors in the human brain using an anatomic standardization technique and [11C]FLB 457. Neuroimage. 10: 666-74. PMID 10600412 DOI: 10.1006/Nimg.1999.0502  0.557
1999 Bergström KA, Halldin C, Savonen A, Okubo Y, Hiltunen J, Nobuhara K, Swahn CG, Karlsson P, McPherson D, Knapp FF, Larsson S, Schnell PO, Farde L. Iodine-123 labelled Z-(R,R)-IQNP: a potential radioligand for visualization of M(1 )and M(2) muscarinic acetylcholine receptors in Alzheimer's disease. European Journal of Nuclear Medicine. 26: 1482-5. PMID 10552091 DOI: 10.1007/S002590050482  0.382
1999 Gulyás B, Halldin C, Karlsson P, Chou YH, Swahn CG, Bönöck P, Paróczai M, Farde L. Brain uptake and plasma metabolism of [11C]vinpocetine: a preliminary PET study in a cynomolgus monkey. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 9: 217-22. PMID 10540601 DOI: 10.1111/Jon199994217  0.705
1999 Olsson H, Halldin C, Swahn CG, Farde L. Quantification of [11C]FLB 457 binding to extrastriatal dopamine receptors in the human brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1164-73. PMID 10532641 DOI: 10.1097/00004647-199910000-00013  0.586
1999 Chou YH, Karlsson P, Halldin C, Olsson H, Farde L. A PET study of D(1)-like dopamine receptor ligand binding during altered endogenous dopamine levels in the primate brain. Psychopharmacology. 146: 220-7. PMID 10525759 DOI: 10.1007/S002130051110  0.52
1999 Langer O, Halldin C, Dollé F, Swahn CG, Olsson H, Karlsson P, Hall H, Sandell J, Lundkvist C, Vaufrey F, Loc'h C, Crouzel C, Mazière B, Farde L. Carbon-11 epidepride: a suitable radioligand for PET investigation of striatal and extrastriatal dopamine D2 receptors. Nuclear Medicine and Biology. 26: 509-18. PMID 10473189 DOI: 10.1016/S0969-8051(99)00005-0  0.556
1999 Lundkvist C, Loc'h C, Halldin C, Bottlaender M, Ottaviani M, Coulon C, Fuseau C, Mathis C, Farde L, Mazière B. Characterization of bromine-76-labelled 5-bromo-6-nitroquipazine for PET studies of the serotonin transporter. Nuclear Medicine and Biology. 26: 501-7. PMID 10473188 DOI: 10.1016/S0969-8051(99)00019-0  0.461
1999 Helfenbein J, Sandell J, Halldin C, Chalon S, Emond P, Okubo Y, Chou YH, Frangin Y, Douziech L, Gareau L, Swahn CG, Besnard JC, Farde L, Guilloteau D. PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter. Nuclear Medicine and Biology. 26: 491-9. PMID 10473187 DOI: 10.1016/S0969-8051(99)00004-9  0.447
1999 Gulyás B, Halldin C, Karlsson P, Chou YH, Swahn CG, Bönöczk P, Farde L. [Cerebral uptake and metabolism of (11C) Vinpocetine in monkeys: PET studies]. Orvosi Hetilap. 140: 1687-91. PMID 10461449  0.668
1999 Andrée B, Thorberg SO, Halldin C, Farde L. Pindolol binding to 5-HT1A receptors in the human brain confirmed with positron emission tomography. Psychopharmacology. 144: 303-5. PMID 10435400 DOI: 10.1007/S002130051009  0.507
1999 Jönsson EG, Nöthen MM, Grünhage F, Farde L, Nakashima Y, Propping P, Sedvall GC. Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers. Molecular Psychiatry. 4: 290-6. PMID 10395223 DOI: 10.1038/Sj.Mp.4000532  0.619
1999 Lundkvist C, Halldin C, Swahn CG, Ginovart N, Farde L. Different brain radioactivity curves in a PET study with [11C]beta-CIT labelled in two different positions. Nuclear Medicine and Biology. 26: 343-50. PMID 10382835 DOI: 10.1016/S0969-8051(98)00111-5  0.328
1999 Nyberg S, Eriksson B, Oxenstierna G, Halldin C, Farde L. Suggested minimal effective dose of risperidone based on PET-measured D2 and 5-HT2A receptor occupancy in schizophrenic patients. The American Journal of Psychiatry. 156: 869-75. PMID 10360125 DOI: 10.1176/Ajp.156.6.869  0.432
1999 Sandell J, Halldin C, Hall H, Thorberg SO, Werner T, Sohn D, Sedvall G, Farde L. Radiosynthesis and autoradiographic evaluation of [11C]NAD-299, a radioligand for visualization of the 5-HT1A receptor. Nuclear Medicine and Biology. 26: 159-64. PMID 10100214 DOI: 10.1016/S0969-8051(98)00091-2  0.642
1999 Ginovart N, Farde L, Halldin C, Swahn CG. Changes in striatal D2-receptor density following chronic treatment with amphetamine as assessed with PET in nonhuman primates. Synapse (New York, N.Y.). 31: 154-62. PMID 10024013 DOI: 10.1002/(Sici)1098-2396(199902)31:2<154::Aid-Syn9>3.0.Co;2-K  0.493
1999 Ito H, Halldin C, Farde L. Localization of 5-HT1A receptors in the living human brain using [carbonyl-11C]WAY-100635: PET with anatomic standardization technique. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 40: 102-9. PMID 9935065  0.392
1999 Ito H, Okubo Y, Halldin C, Farde L. Mapping of central D2 dopamine receptors in man using [11C]raclopride: PET with anatomic standardization technique. Neuroimage. 9: 235-42. PMID 9927552 DOI: 10.1006/Nimg.1998.0401  0.534
1999 Hall H, Halldin C, Guilloteau D, Chalon S, Emond P, Besnard J, Farde L, Sedvall G. Visualization of the dopamine transporter in the human brain postmortem with the new selective ligand [125I]PE2I. Neuroimage. 9: 108-16. PMID 9918732 DOI: 10.1006/Nimg.1998.0366  0.594
1998 Nyberg S, Dencker SJ, Malm U, Dahl ML, Svenson JO, Halldin C, Naskashima Y, Farde L. D(2)- and 5-HT(2) receptor occupancy in high-dose neuroleptic-treated patients. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 1: 95-101. PMID 11281952 DOI: 10.1017/S1461145798001229  0.439
1998 Halldin C, Foged C, Chou YH, Karlsson P, Swahn CG, Sandell J, Sedvall G, Farde L. Carbon-11-NNC 112: a radioligand for PET examination of striatal and neocortical D1-dopamine receptors. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 39: 2061-8. PMID 9867142  0.659
1998 Hall H, Halldin C, Farde L, Sedvall G. Whole hemisphere autoradiography of the postmortem human brain. Nuclear Medicine and Biology. 25: 715-9. PMID 9863555 DOI: 10.1016/S0969-8051(98)00053-5  0.624
1998 Farde L, Ito H, Swahn CG, Pike VW, Halldin C. Quantitative analyses of carbonyl-carbon-11-WAY-100635 binding to central 5-hydroxytryptamine-1A receptors in man. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 39: 1965-71. PMID 9829590  0.406
1998 Ito H, Hietala J, Blomqvist G, Halldin C, Farde L. Comparison of the transient equilibrium and continuous infusion method for quantitative PET analysis of [11C]raclopride binding. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 941-50. PMID 9740097 DOI: 10.1097/00004647-199809000-00003  0.428
1998 Foged C, Halldin C, Swahn CG, Ginovart N, Karlsson P, Lundkvist C, Farde L. [11C]NNC 22-0215, a metabolically stable dopamine D1 radioligand for PET. Nuclear Medicine and Biology. 25: 503-8. PMID 9720669 DOI: 10.1016/S0969-8051(98)00010-9  0.561
1998 Nyberg S, Nilsson U, Okubo Y, Halldin C, Farde L. Implications of brain imaging for the management of schizophrenia. International Clinical Psychopharmacology. 13: S15-20. PMID 9690965 DOI: 10.1097/00004850-199803003-00003  0.482
1998 Andrée B, Nyberg S, Ito H, Ginovart N, Brunner F, Jaquet F, Halldin C, Farde L. Positron emission tomographic analysis of dose-dependent MDL 100,907 binding to 5-hydroxytryptamine-2A receptors in the human brain. Journal of Clinical Psychopharmacology. 18: 317-23. PMID 9690698 DOI: 10.1097/00004714-199808000-00012  0.489
1998 Nordström AL, Farde L. Plasma prolactin and central D2 receptor occupancy in antipsychotic drug-treated patients. Journal of Clinical Psychopharmacology. 18: 305-10. PMID 9690696 DOI: 10.1097/00004714-199808000-00010  0.404
1998 Emond P, Farde L, Chalon S, Belzung C, Mauclaire V, Chiron JP, Halldin C, Besnard JC, Guilloteau D. Toxicity, mutagenicity, and behavioral effects of beta-CIT, a ligand for dopamine transporter exploration by SPECT. Nuclear Medicine and Biology. 25: 405-9. PMID 9639303 DOI: 10.1016/S0969-8051(97)00227-8  0.319
1998 Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Farde L, Ginovart N, Luthra SK, Gunn RN, Bench CJ, Sargent PA, Grasby PM. Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635--explanation of high signal contrast in PET and an aid to biomathematical modelling. Nuclear Medicine and Biology. 25: 215-23. PMID 9620626 DOI: 10.1016/S0969-8051(97)00206-0  0.487
1998 Bergström KA, Halldin C, Hiltunen J, Swahn CG, Ito H, Ginovart N, Hall H, McPherson DW, Knapp FF, Larsson S, Schnell PO, Farde L. Evaluation and metabolite studies of 125I- and 123I-labelled E-(R,R)-IQNP: potential radioligands for visualization of M1 muscarinic acetylcholine receptors in brain. Nuclear Medicine and Biology. 25: 209-14. PMID 9620625 DOI: 10.1016/S0969-8051(97)00198-4  0.395
1998 Kuikka JT, Baulieu JL, Hiltunen J, Halldin C, Bergström KA, Farde L, Emond P, Chalon S, Yu M, Nikula T, Laitinen T, Karhu J, Tupala E, Hallikainen T, Kolehmainen V, et al. Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging. European Journal of Nuclear Medicine. 25: 531-4. PMID 9575250 DOI: 10.1007/S002590050254  0.417
1998 Pike VW, Halldin C, McCarron JA, Lundkvist C, Hirani E, Olsson H, Hume SP, Karlsson P, Osman S, Swahn CG, Hall H, Wikström H, Mensonidas M, Poole KG, Farde L. [carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT1A receptors in vitro and in vivo. European Journal of Nuclear Medicine. 25: 338-46. PMID 9553162 DOI: 10.1007/S002590050230  0.519
1998 Nordström AL, Nyberg S, Olsson H, Farde L. Positron emission tomography finding of a high striatal D2 receptor occupancy in olanzapine-treated patients. Archives of General Psychiatry. 55: 283-4. PMID 9510228 DOI: 10.1001/Archpsyc.55.3.283  0.465
1998 Ito H, Nyberg S, Halldin C, Lundkvist C, Farde L. PET imaging of central 5-HT2A receptors with carbon-11-MDL 100,907. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 39: 208-14. PMID 9443763  0.461
1998 Hiltunen J, Akerman KK, Kuikka JT, Bergström KA, Halldin C, Nikula T, Räsänen P, Tiihonen J, Vauhkonen M, Karhu J, Kupila J, Länsimies E, Farde L. Iodine-123 labeled nor-beta-CIT as a potential tracer for serotonin transporter imaging in the human brain with single-photon emission tomography. European Journal of Nuclear Medicine. 25: 19-23. PMID 9396870 DOI: 10.1007/S002590050189  0.34
1998 Hall H, Halldin C, Farde L, Sedvall G. Distribution of Serotonin Receptor Subtypes in the Post-Mortem Human Brain Neuroimage. 7: S291. DOI: 10.1016/S1053-8119(18)31124-8  0.533
1998 Farde L, Andrée B, Ginovart N, Halldin C, Thorberg S. PET determination of robalzotan occupancy of 5-HT1A receptors in the monkey brain European Neuropsychopharmacology. 8: S168. DOI: 10.1016/S0924-977X(98)80214-9  0.487
1998 Farde L, Olsson H, Talvik-Lotfi M, Halldin C. Striatai and extrastriatal D2-dopamine receptor occupancy during haloperidol and ciozapine treatment European Neuropsychopharmacology. 8: S83. DOI: 10.1016/S0924-977X(98)80050-3  0.442
1997 Farde L. Brain imaging of schizophrenia--the dopamine hypothesis. Schizophrenia Research. 28: 157-62. PMID 9468350 DOI: 10.1016/S0920-9964(97)00121-7  0.429
1997 Farde L, Suhara T, Nyberg S, Karlsson P, Nakashima Y, Hietala J, Halldin C. A PET-study of [11C]FLB 457 binding to extrastriatal D2-dopamine receptors in healthy subjects and antipsychotic drug-treated patients. Psychopharmacology. 133: 396-404. PMID 9372541 DOI: 10.1007/S002130050420  0.564
1997 Günther I, Hall H, Halldin C, Swahn CG, Farde L, Sedvall G. [125I] beta-CIT-FE and [125I] beta-CIT-FP are superior to [125I] beta-CIT for dopamine transporter visualization: autoradiographic evaluation in the human brain. Nuclear Medicine and Biology. 24: 629-34. PMID 9352533 DOI: 10.1016/S0969-8051(97)00081-4  0.503
1997 Lundkvist C, Halldin C, Ginovart N, Swahn CG, Farde L. [18F] beta-CIT-FP is superior to [11C] beta-CIT-FP for quantitation of the dopamine transporter. Nuclear Medicine and Biology. 24: 621-7. PMID 9352532 DOI: 10.1016/S0969-8051(97)00077-2  0.359
1997 Farde L, Ginovart N, Ito H, Lundkvist C, Pike VW, McCarron JA, Halldin C. PET-characterization of [carbonyl-11C]WAY-100635 binding to 5-HT1A receptors in the primate brain. Psychopharmacology. 133: 196-202. PMID 9342787 DOI: 10.1007/S002130050391  0.56
1997 Nyberg S, Farde L, Halldin C. Delayed normalization of central D2 dopamine receptor availability after discontinuation of haloperidol decanoate. Preliminary findings. Archives of General Psychiatry. 54: 953-8. PMID 9337776 DOI: 10.1001/Archpsyc.1997.01830220079011  0.496
1997 Foged C, Halldin C, Loc'h C, Mazière B, Pauli S, Maziére M, Hansen HC, Suhara T, Swahn CG, Karlsson P, Farde L. Bromine-76 and carbon-11 labelled NNC 13-8199, metabolically stable benzodiazepine receptor agonists as radioligands for positron emission tomography. European Journal of Nuclear Medicine. 24: 1261-7. PMID 9323267 DOI: 10.1007/S002590050150  0.496
1997 Hall H, Halldin C, Jerning E, Osterlund M, Farde L, Sedvall G. Autoradiographic comparison of [125I]epidepride and [125I]NCQ 298 binding to human brain extrastriated dopamine receptors. Nuclear Medicine and Biology. 24: 389-93. PMID 9290072 DOI: 10.1016/S0969-8051(97)80004-2  0.669
1997 Andrée B, Halldin C, Vrijmoed-de Vries M, Farde L. Central 5-HT2A and D2 dopamine receptor occupancy after sublingual administration of ORG 5222 in healthy men. Psychopharmacology. 131: 339-45. PMID 9226735 DOI: 10.1007/S002130050301  0.55
1997 Farde L, Mack RJ, Nyberg S, Halldin C. D2 occupancy, extrapyramidal side effects and antipsychotic drug treatment: a pilot study with sertindole in healthy subjects. International Clinical Psychopharmacology. 12: S3-7. PMID 9179638 DOI: 10.1097/00004850-199702001-00002  0.475
1997 Bergström KA, Halldin C, Hall H, Lundkvist C, Ginovart N, Swahn CG, Farde L. In vitro and in vivo characterisation of nor-beta-CIT: a potential radioligand for visualisation of the serotonin transporter in the brain. European Journal of Nuclear Medicine. 24: 596-601. PMID 9169564 DOI: 10.1007/Bf00841395  0.371
1997 Ginovart N, Lundin A, Farde L, Halldin C, Bäckman L, Swahn CG, Pauli S, Sedvall G. PET study of the pre- and post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease. Brain : a Journal of Neurology. 120: 503-14. PMID 9126061 DOI: 10.1093/Brain/120.3.503  0.605
1997 Ginovart N, Farde L, Halldin C, Swahn CG. Effect of reserpine-induced depletion of synaptic dopamine on [11C]raclopride binding to D2-dopamine receptors in the monkey brain. Synapse (New York, N.Y.). 25: 321-5. PMID 9097390 DOI: 10.1002/(Sici)1098-2396(199704)25:4<321::Aid-Syn2>3.0.Co;2-C  0.539
1997 Volkow ND, Rosen B, Farde L. Imaging the living human brain: magnetic resonance imaging and positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 94: 2787-8. PMID 9096295 DOI: 10.1073/pnas.94.7.2787  0.332
1997 Hall H, Lundkvist C, Halldin C, Farde L, Pike VW, McCarron JA, Fletcher A, Cliffe IA, Barf T, Wikström H, Sedvall G. Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635. Brain Research. 745: 96-108. PMID 9037397 DOI: 10.1016/S0006-8993(96)01131-6  0.64
1997 Farde L, Gustavsson JP, Jönsson E. D2 dopamine receptors and personality traits. Nature. 385: 590. PMID 9024656 DOI: 10.1038/385590a0  0.428
1997 Nyberg S, Farde L, Halldin C. A PET study of 5-HT2 and D2 dopamine receptor occupancy induced by olanzapine in healthy subjects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 16: 1-7. PMID 8981383 DOI: 10.1016/S0893-133X(96)00218-7  0.439
1997 Farde L. S.26.03 A PET-study of extrastriatal D2-dopamine receptors European Neuropsychopharmacology. 7: S129-S130. DOI: 10.1016/S0924-977X(97)88443-X  0.41
1997 Karlsson P, Farde L, Halldin C, Sedvall G. D1-Dopamine receptors in schizophrenia examined by pet Schizophrenia Research. 24: 178-179. DOI: 10.1016/S0920-9964(97)82513-3  0.626
1997 Bymaster FP, Whitesitt CA, Shannon HE, DeLapp N, Ward JS, Calligaro DO, Shipley LA, Buelke-Sam JL, Bodick NC, Farde L, Sheardown MJ, Olesen PH, Hansen KT, Suzdak PD, Swedberg MD, et al. Xanomeline: A selective muscarinic agonist for the treatment of Alzheimer's disease Drug Development Research. 40: 158-170. DOI: 10.1002/(SICI)1098-2299(199702)40:2<158::AID-DDR6>3.0.CO;2-K  0.376
1996 Hall H, Halldin C, Dijkstra D, Wikström H, Wise LD, Pugsley TA, Sokoloff P, Pauli S, Farde L, Sedvall G. Autoradiographic localisation of D3-dopamine receptors in the human brain using the selective D3-dopamine receptor agonist (+)-[3H]PD 128907. Psychopharmacology. 128: 240-7. PMID 8972543 DOI: 10.1007/S002130050131  0.606
1996 Foged C, Halldin C, Loc'h C, Mazière B, Karlsson P, Mazière M, Swahn CG, Farde L. 11C- and 76Br-labelled NNC 22-0010, selective dopamine D1 receptor radioligands for PET. Nuclear Medicine and Biology. 23: 837-44. PMID 8940728 DOI: 10.1016/0969-8051(96)00083-2  0.537
1996 Loc'h C, Halldin C, Bottlaender M, Swahn CG, Moresco RM, Mazière M, Farde L, Mazière B. Preparation of [76Br]FLB 457 and [76Br]FLB 463 for examination of striatal and extrastriatal dopamine D-2 receptors with PET. Nuclear Medicine and Biology. 23: 813-9. PMID 8940725 DOI: 10.1016/0969-8051(96)00078-9  0.522
1996 Nyberg S, Farde L, Halldin C. Test-retest reliability of central [11C]raclopride binding at high D2 receptor occupancy. A PET study in haloperidol-treated patients. Psychiatry Research. 67: 163-71. PMID 8912956 DOI: 10.1016/0925-4927(96)02921-6  0.534
1996 Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Ginovart N, Luthra SK, Bench CJ, Grasby PM, Wikström H, Barf T, Cliffe IA, Fletcher A, Farde L. Characterization of the radioactive metabolites of the 5-HT1A receptor radioligand, [O-methyl-11C]WAY-100635, in monkey and human plasma by HPLC: comparison of the behaviour of an identified radioactive metabolite with parent radioligand in monkey using PET. Nuclear Medicine and Biology. 23: 627-34. PMID 8905828 DOI: 10.1016/0969-8051(96)00061-3  0.467
1996 Halldin C, Farde L, Lundkvist C, Ginovart N, Nakashima Y, Karlsson P, Swahn CG. [11C]beta-CIT-FE, a radioligand for quantitation of the dopamine transporter in the living brain using positron emission tomography. Synapse (New York, N.Y.). 22: 386-90. PMID 8867033 DOI: 10.1002/(Sici)1098-2396(199604)22:4<386::Aid-Syn10>3.0.Co;2-W  0.401
1996 Farde L, Suhara T, Halldin C, Nybäck H, Nakashima Y, Swahn CG, Karlsson P, Ginovart N, Bymaster FP, Shannon HE, Foged C, Suzdak PD, Sauerberg P. PET study of the M1-agonists [11C]xanomeline and [11C]butylthio-TZTP in monkey and man. Dementia (Basel, Switzerland). 7: 187-95. PMID 8835881 DOI: 10.1159/000106877  0.511
1996 Suhara T, Farde L, Halldin C, NÃ¥gren K, Karlsson P. Effects of cocaine on [11C]norepinephrine and [11C] beta-CIT uptake in the primate peripheral organs measured by PET. Annals of Nuclear Medicine. 10: 85-8. PMID 8814732 DOI: 10.1007/Bf03165058  0.317
1996 NÃ¥gren K, Halldin C, Swahn CG, Suhara T, Farde L. [11C]metaraminol, a false neurotransmitter: preparation, metabolite studies and positron emission tomography examination in monkey. Nuclear Medicine and Biology. 23: 221-7. PMID 8782229 DOI: 10.1016/0969-8051(95)02050-0  0.397
1996 Foged C, Halldin C, Hiltunen J, Braestrup C, Thomsen C, Hansen HC, Suhara T, Pauli S, Swahn CG, Karlsson P, Larsson S, Farde L. Development of 123I-labelled NNC 13-8241 as a radioligand for SPECT visualization of benzodiazepine receptor binding. Nuclear Medicine and Biology. 23: 201-9. PMID 8782227 DOI: 10.1016/0969-8051(95)02041-1  0.467
1996 Farde L. The advantage of using positron emission tomography in drug research. Trends in Neurosciences. 19: 211-4. PMID 8761953 DOI: 10.1016/0166-2236(96)40002-9  0.373
1996 Nyberg S, Nakashima Y, Nordström AL, Halldin C, Farde L. Positron emission tomography of in-vivo binding characteristics of atypical antipsychotic drugs. Review of D2 and 5-HT2 receptor occupancy studies and clinical response. The British Journal of Psychiatry. Supplement. 40-4. PMID 8733822 DOI: 10.1192/S0007125000298309  0.44
1996 Hall H, Farde L, Halldin C, Hurd YL, Pauli S, Sedvall G. Autoradiographic localization of extrastriatal D2-dopamine receptors in the human brain using [125I]epidepride. Synapse (New York, N.Y.). 23: 115-23. PMID 8723716 DOI: 10.1002/(Sici)1098-2396(199606)23:2<115::Aid-Syn7>3.0.Co;2-C  0.645
1996 Kuikka JT, Hiltunen J, Foged C, Bergström KA, Halldin C, Akerman K, Tiihonen J, Farde L. Initial human studies with single-photon emission tomography using iodine-123 labelled 3-(5-cyclopropyl-1,2,4-oxadiazo-3-yl)- 7-iodo-5, 6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]-benzodiazepine (NNC 13-8241). European Journal of Nuclear Medicine. 23: 798-803. PMID 8662119 DOI: 10.1007/Bf00843709  0.438
1996 Lundkvist C, Halldin C, Ginovart N, Nyberg S, Swahn CG, Carr AA, Brunner F, Farde L. [11C]MDL 100907, a radioligland for selective imaging of 5-HT(2A) receptors with positron emission tomography. Life Sciences. 58: PL 187-92. PMID 8602111 DOI: 10.1016/0024-3205(96)00013-6  0.527
1996 Sedvall G, Farde L. Dopamine receptors in schizophrenia. Lancet. 347: 264. PMID 8551909 DOI: 10.1016/S0140-6736(96)90440-7  0.566
1996 NORDSTRÖM A, FARDE L, NYBERG S, KARLSSON P, HALLDIN C, SEDVALL G. Dr. Nordström and Colleagues Reply American Journal of Psychiatry. 153: 1240-1240. DOI: 10.1176/Ajp.153.9.1240  0.431
1996 Karlsson P, Farde L, Halldin C, Sedvall G. Reduced D1-dopamine receptor binding in schizophrenia — Relation to psychopathology European Neuropsychopharmacology. 6: 212-213. DOI: 10.1016/0924-977X(96)88301-5  0.606
1996 Hall H, Lundkvist C, Halldin C, Pike V, McCarron J, Fletcher A, Cliffe I, Farde L, Sedvall G. Autoradiographic localization of 5-HT1A-receptors in the human brain European Neuropsychopharmacology. 6: 212. DOI: 10.1016/0924-977X(96)88297-6  0.582
1996 Farde L, Ginovart N, Halldin C. Pet-studies on the dopamine system in vivo European Neuropsychopharmacology. 6: 165. DOI: 10.1016/0924-977X(96)88068-0  0.324
1996 Hall H, Hurd Y, Suzuki M, Farde L, Halldin C, Sedvall G. Distribution of dopamine receptor subtypes in the post-mortem human brain European Neuropsychopharmacology. 6: 157. DOI: 10.1016/0924-977X(96)88033-3  0.618
1996 Ginovart N, Lundin A, Farde L, Halldin C, Swahn C, Pauli S, Sedvall G. In vivo examination of the Pre- and postsynaptic dopamine neurons in huntington's disease European Neuropsychopharmacology. 6: 130. DOI: 10.1016/0924-977X(96)87905-3  0.504
1996 Farde L, Ginovart N, Halldin C. PET studies on the dopamine system in vivo European Neuropsychopharmacology. 6: S4-8. DOI: 10.1016/0924-977X(96)83164-6  0.436
1996 Karlsson P, Farde L, Halldin C, Sedvall G. PET D1-receptor studies in schizophrenia European Psychiatry. 11: 231s-232s. DOI: 10.1016/0924-9338(96)88691-3  0.545
1996 Nordström A, Nyberg S, Farde L. Dopamine and serotonin receptor occupancy in patients treated with antipsychotics European Psychiatry. 11: 202s. DOI: 10.1016/0924-9338(96)88581-6  0.318
1996 Nordström A, Farde L. Dopamine receptors and neurological side effects European Psychiatry. 11: 183s. DOI: 10.1016/0924-9338(96)88511-7  0.319
1996 Nyberg S, Farde L, Halldin C. Long-time persistence of D2 dopamine receptor occupancy after discontinuation of haloperidol decanoate Schizophrenia Research. 18: 199-200. DOI: 10.1016/0920-9964(96)85622-2  0.324
1996 Karlsson P, Farde L, Halldin C, Sedvall G. Decrease of D1-dopamine receptor binding in the frontal cortex of neuroleptic naive schizophrenic patients measured by PET Schizophrenia Research. 18: 198. DOI: 10.1016/0920-9964(96)85618-0  0.604
1996 Müller L, Halldin C, Lundkvist C, Swahn C-, Foged C, Hall H, Karlsson P, Ginovart N, Nakashima Y, Suhara T, Farde L. Development of radioligands for the dopamine transporter Journal of Radioanalytical and Nuclear Chemistry Articles. 206: 133-144. DOI: 10.1007/Bf02040050  0.371
1995 Farde L, Halldin C, NÃ¥gren K, Karlsson P, Swahn CG, Suhara T. PET examination of the monkey heart with high specific radioactivity [11C]norepinephrine and [11C]metaraminol. Nuclear Medicine and Biology. 22: 1053-6. PMID 8998466 DOI: 10.1016/0969-8051(95)02030-6  0.388
1995 Swahn CG, Halldin C, NÃ¥gren K, Farde L. An HPLC-method for determination of ligand metabolism during PET studies with [11C]metaraminol and [11C]norepinephrine. Nuclear Medicine and Biology. 22: 1045-8. PMID 8998464 DOI: 10.1016/0969-8051(95)02028-4  0.385
1995 Nyberg S, Nordström AL, Halldin C, Farde L. Positron emission tomography studies on D2 dopamine receptor occupancy and plasma antipsychotic drug levels in man. International Clinical Psychopharmacology. 10: 81-5. PMID 8866769  0.369
1995 Sedvall G, Pauli S, Karlsson P, Farde L, Nordström AL, Nyberg S, Halldin C. PET imaging of neuroreceptors in schizophrenia. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 5: 25-30. PMID 8775755 DOI: 10.1016/0924-977X(95)00021-G  0.684
1995 Nyberg S, Farde L, Bartfai A, Halldin C. Central D2 receptor occupancy and effects of zuclopenthixol acetate in humans. International Clinical Psychopharmacology. 10: 221-7. PMID 8748043 DOI: 10.1097/00004850-199511000-00003  0.43
1995 Karlsson P, Smith L, Farde L, Härnryd C, Sedvall G, Wiesel FA. Lack of apparent antipsychotic effect of the D1-dopamine receptor antagonist SCH39166 in acutely ill schizophrenic patients. Psychopharmacology. 121: 309-16. PMID 8584611 DOI: 10.1007/BF02246068  0.534
1995 Karlsson P, Sedvall G, Halldin C, Swahn CG, Farde L. Evaluation of SCH 39166 as PET ligand for central D1 dopamine receptor binding and occupancy in man. Psychopharmacology. 121: 300-8. PMID 8584610 DOI: 10.1007/Bf02246067  0.683
1995 Lundkvist C, Halldin C, Swahn CG, Hall H, Karlsson P, Nakashima Y, Wang S, Milius RA, Neumeyer JL, Farde L. [O-methyl-11C]beta-CIT-FP, a potential radioligand for quantitation of the dopamine transporter: preparation, autoradiography, metabolite studies, and positron emission tomography examinations. Nuclear Medicine and Biology. 22: 905-13. PMID 8547888 DOI: 10.1016/0969-8051(95)00029-W  0.401
1995 Müller L, Hall H, Halldin C, Farde L, Hohlweg R, Suzdak PD, Nielsen EB, Foged C. Synthesis and binding properties of [3H]NNC 12-0781, a new radioligand for the dopamine reuptake system. Nuclear Medicine and Biology. 22: 711-7. PMID 8535331 DOI: 10.1016/0969-8051(95)00011-L  0.383
1995 Nyberg S, Farde L, Halldin C, Dahl ML, Bertilsson L. D2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate. The American Journal of Psychiatry. 152: 173-8. PMID 7840348  0.34
1995 Bergström KA, Halldin C, Kuikka JT, Swahn CG, Tiihonen J, Hiltunen J, Länsimies E, Farde L. Lipophilic metabolite of [123I]beta-CIT in human plasma may obstruct quantitation of the dopamine transporter. Synapse (New York, N.Y.). 19: 297-300. PMID 7792723 DOI: 10.1002/Syn.890190407  0.387
1995 Halldin C, Farde L, Högberg T, Mohell N, Hall H, Suhara T, Karlsson P, Nakashima Y, Swahn CG. Carbon-11-FLB 457: a radioligand for extrastriatal D2 dopamine receptors. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 36: 1275-81. PMID 7790956  0.473
1995 Karlsson P, Farde L, Halldin C, Sedvall G, Ynddal L, Sloth-Nielsen M. Oral administration of NNC 756--a placebo controlled PET study of D1-dopamine receptor occupancy and pharmacodynamics in man. Psychopharmacology. 119: 1-8. PMID 7675940 DOI: 10.1007/Bf02246046  0.633
1995 Sedvall G, Farde L. Chemical brain anatomy in schizophrenia. Lancet. 346: 743-9. PMID 7658878 DOI: 10.1016/S0140-6736(95)91508-7  0.439
1995 Sedvall G, Pauli S, Farde L, Karlsson P, Nyberg S, Nordström AL. Recent developments in PET scan imaging of neuroreceptors in schizophrenia. The Israel Journal of Psychiatry and Related Sciences. 32: 22-9. PMID 7622344  0.631
1995 Sedvall G, Farde L, Hall H, Halldin C, Karlsson P, Nordström AL, Nyberg S, Pauli S. Utilization of radioligands in schizophrenia research. Clinical Neuroscience (New York, N.Y.). 3: 112-21. PMID 7583617  0.612
1995 Nordström AL, Farde L, Nyberg S, Karlsson P, Halldin C, Sedvall G. D1, D2, and 5-HT2 receptor occupancy in relation to clozapine serum concentration: a PET study of schizophrenic patients. The American Journal of Psychiatry. 152: 1444-9. PMID 7573582 DOI: 10.1176/Ajp.152.10.1444  0.619
1995 Farde L, Hall H, Pauli S, Halldin C. Variability in D2-dopamine receptor density and affinity: a PET study with [11C]raclopride in man. Synapse (New York, N.Y.). 20: 200-8. PMID 7570351 DOI: 10.1002/Syn.890200303  0.541
1995 Hall H, Halldin C, Nyberg S, Farde L, Sedvall G. Effect of clozapine and risperidone on 5-HT2 and D2-dopamine receptor binding in the post-mortem human brain. An autoradiographic study. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 5: 19-25. PMID 7542051 DOI: 10.1016/0924-977X(94)00127-W  0.663
1995 Farde L, Nyberg S, Oxenstierna G, Nakashima Y, Halldin C, Ericsson B. Positron emission tomography studies on D2 and 5-HT2 receptor binding in risperidone-treated schizophrenic patients. Journal of Clinical Psychopharmacology. 15: 19S-23S. PMID 7537284 DOI: 10.1097/00004714-199502001-00004  0.43
1995 Nordström AL, Farde L, Eriksson L, Halldin C. No elevated D2 dopamine receptors in neuroleptic-naive schizophrenic patients revealed by positron emission tomography and [11C]N-methylspiperone. Psychiatry Research. 61: 67-83. PMID 7480390 DOI: 10.1016/0925-4927(95)02732-D  0.553
1995 Farde L, Nordström A, Karlsson P, Halldin C, Sedvall G. Positron Emission Tomography Studies on Dopamine Receptors in Schizophrenia Clinical Neuropharmacology. 18: S121-S129. DOI: 10.1097/00002826-199501001-00014  0.603
1995 HALL H, FARDE L, HALLDIN C, NYBERG S, MOHELL N, JACKSON D, SEDVALL G. Extra-striatal dopamine receptors studied with [125I]epideprideIn VITRO and [[11C]FLB 457in vivo Pharmacological Research. 31: 29-29. DOI: 10.1016/1043-6618(95)86377-X  0.573
1995 Hall H, Halldin C, Suzuki M, Dijkstra D, Wikström H, Wise L, Pugsley T, Hurd Y, Farde L, Pauli S, Sedvall G. P-4-61 Autoradiographic comparison of D2- and D3-dopamine receptor localization in the post mortem human brain using [125I]epidepride and [3H]PD 128907 European Neuropsychopharmacology. 5: 346. DOI: 10.1016/0924-977X(95)90581-W  0.597
1995 Karlsson P, Farde L, Halldin C, Sedvall G. Decreased D1-dopamine receptor binding in drug naive schizophrenic patients examined by pet Schizophrenia Research. 15: 86. DOI: 10.1016/0920-9964(95)95267-D  0.658
1995 Loc'h C, Müller L, Ottaviani M, Halldin C, Farde L, Mazière B. Synthesis of 2β-carbomethoxy-3β-(4-[76Br]bromophenyl)tropane ([76Br]β-CBT), a pet tracer for in vivo imaging of the dopamine uptake sites Journal of Labelled Compounds and Radiopharmaceuticals. 36: 385-392. DOI: 10.1002/Jlcr.2580360412  0.305
1994 Halldin C, Högberg T, Farde L. Fluorine-18-labelled NCQ 115, a selective dopamine D-2 receptor ligand. Preparation and positron emission tomography. Nuclear Medicine and Biology. 21: 627-31. PMID 9234320 DOI: 10.1016/0969-8051(94)90028-0  0.464
1994 Farde L, Halldin C, Müller L, Suhara T, Karlsson P, Hall H. PET study of [11C]beta-CIT binding to monoamine transporters in the monkey and human brain. Synapse (New York, N.Y.). 16: 93-103. PMID 8197578 DOI: 10.1002/Syn.890160203  0.445
1994 NÃ¥gren K, Schoeps KO, Halldin C, Swahn CG, Farde L. Selective synthesis of racemic 1-11C-labelled norepinephrine, octopamine, norphenylephrine and phenylethanolamine using [11C]nitromethane. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 45: 515-21. PMID 8186772 DOI: 10.1016/0969-8043(94)90117-1  0.315
1994 Sedvall G, Karlsson P, Lundin A, Anvret M, Suhara T, Halldin C, Farde L. Dopamine D1 receptor number--a sensitive PET marker for early brain degeneration in Huntington's disease. European Archives of Psychiatry and Clinical Neuroscience. 243: 249-55. PMID 8172940 DOI: 10.1007/Bf02191583  0.678
1994 Müller L, Halldin C, Foged C, Karlsson P, Hall H, Swahn CG, Suzdak PD, Hohlweg R, Nielsen EB, Farde L. Preparation of a potential positron emission tomographic radioligand for the dopamine transporter. European Journal of Nuclear Medicine. 21: 131-7. PMID 8162936 DOI: 10.1007/Bf00175760  0.482
1994 Farde L, Pauli S, Litton JE, Halldin C, Neiman J, Sedvall G. PET-determination of benzodiazepine receptor binding in studies on alcoholism. Exs. 71: 143-53. PMID 8032146  0.555
1994 Farde L, Halldin C, NÃ¥gren K, Suhara T, Karlsson P, Schoeps KO, Swahn CG, Bone D. Positron emission tomography shows high specific uptake of racemic carbon-11 labelled norepinephrine in the primate heart. European Journal of Nuclear Medicine. 21: 345-7. PMID 8005159 DOI: 10.1007/Bf00947971  0.353
1994 Farde L, Nordström AL, Nyberg S, Halldin C, Sedvall G. D1-, D2-, and 5-HT2-receptor occupancy in clozapine-treated patients. The Journal of Clinical Psychiatry. 55: 67-9. PMID 7961577  0.571
1994 Wiesel FA, Nordström AL, Farde L, Eriksson B. An open clinical and biochemical study of ritanserin in acute patients with schizophrenia. Psychopharmacology. 114: 31-8. PMID 7846205 DOI: 10.1007/Bf02245441  0.437
1994 Movin-Osswald G, Karlsson P, Hammarlund-Udenaes M, Farde L. Influence of rate of administration of raclopride on akathisia and prolactin response. Psychopharmacology. 114: 248-56. PMID 7838916 DOI: 10.1007/Bf02244845  0.311
1994 Hall H, Sedvall G, Magnusson O, Kopp J, Halldin C, Farde L. Distribution of D1- and D2-dopamine receptors, and dopamine and its metabolites in the human brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 11: 245-56. PMID 7531978 DOI: 10.1038/Sj.Npp.1380111  0.659
1994 Farde L, Nordström A, Nyberg S, Halldin C. D2 and 5-HT2 receptor occupancy in antipsychotic drug treated patients European Neuropsychopharmacology. 4: 221-223. DOI: 10.1016/0924-977X(94)90051-5  0.463
1994 Farde L, Suhara T, Halldin C, Karlsson P, Nybäck H, Müller L, Fuged C, Sauerberg P, Lucas R. New radioligands for pet-examination of central muscarinic receptors Neurobiology of Aging. 15: S105. DOI: 10.1016/0197-4580(94)92885-1  0.512
1994 Swahn C, Halldin C, Farde L, Sedvall G. Metabolism of the PET ligand [11C]SCH 23390. Identification of two radiolabelled metabolites with HPLC Human Psychopharmacology: Clinical and Experimental. 9: 25-31. DOI: 10.1002/Hup.470090103  0.582
1993 Müller L, Halldin C, Farde L, Karlsson P, Hall H, Swahn CG, Neumeyer J, Gao Y, Milius R. [11C] beta-CIT, a cocaine analogue. Preparation, autoradiography and preliminary PET investigations. Nuclear Medicine and Biology. 20: 249-55. PMID 8485483 DOI: 10.1016/0969-8051(93)90045-V  0.361
1993 Litton JE, Neiman J, Pauli S, Farde L, Hindmarsh T, Halldin C, Sedvall G. PET analysis of [11C]flumazenil binding to benzodiazepine receptors in chronic alcohol-dependent men and healthy controls. Psychiatry Research. 50: 1-13. PMID 8390063 DOI: 10.1016/0925-4927(93)90019-E  0.614
1993 Schoeps KO, Halldin C, NÃ¥gren K, Swahn CG, Karlsson P, Hall H, Farde L. Preparation of [1-11C]dopamine, [1-11C]p-tyramine and [1-11C]m-tyramine. Autoradiography and PET examination of [1-11C]dopamine in primates. Nuclear Medicine and Biology. 20: 669-78. PMID 8358354 DOI: 10.1016/0969-8051(93)90038-V  0.501
1993 Halldin C, Foged C, Farde L, Karlsson P, Hansen K, Grønvald F, Swahn CG, Hall H, Sedvall G. [11C]NNC 687 and [11C]NNC 756, dopamine D-1 receptor ligands. Preparation, autoradiography and PET investigation in monkey. Nuclear Medicine and Biology. 20: 945-53. PMID 8298574 DOI: 10.1016/0969-8051(93)90095-C  0.673
1993 Farde L, Nordström AL. PET examination of central D2 dopamine receptor occupancy in relation to extrapyramidal syndromes in patients being treated with neuroleptic drugs. Psychopharmacology Series. 10: 94-100. PMID 8103229 DOI: 10.1007/978-3-642-78010-3_9  0.454
1993 Nordström AL, Farde L, Wiesel FA, Forslund K, Pauli S, Halldin C, Uppfeldt G. Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: a double-blind PET study of schizophrenic patients. Biological Psychiatry. 33: 227-35. PMID 8097114 DOI: 10.1016/0006-3223(93)90288-O  0.519
1993 Karlsson P, Farde L, Halldin C, Swahn CG, Sedvall G, Foged C, Hansen KT, Skrumsager B. PET examination of [11C]NNC 687 and [11C]NNC 756 as new radioligands for the D1-dopamine receptor. Psychopharmacology. 113: 149-56. PMID 7855175 DOI: 10.1007/Bf02245691  0.682
1993 Nordström AL, Farde L, Halldin C. High 5-HT2 receptor occupancy in clozapine treated patients demonstrated by PET. Psychopharmacology. 110: 365-7. PMID 7831432 DOI: 10.1007/Bf02251294  0.419
1993 Nyberg S, Farde L, Eriksson L, Halldin C, Eriksson B. 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology. 110: 265-72. PMID 7530376 DOI: 10.1007/Bf02251280  0.497
1992 Farde L. Selective D1- and D2-dopamine receptor blockade both induces akathisia in humans--a PET study with [11C]SCH 23390 and [11C]raclopride. Psychopharmacology. 107: 23-9. PMID 1534178 DOI: 10.1007/Bf02244961  0.57
1992 Nordström AL, Farde L, Halldin C. Time course of D2-dopamine receptor occupancy examined by PET after single oral doses of haloperidol. Psychopharmacology. 106: 433-8. PMID 1533719 DOI: 10.1007/Bf02244811  0.486
1992 Sedvall CG, Farde L, Hall H, Halldin C, Karlsson P, Brene S, Lindefors N, Persson H, Chipkin RE, Ehrlich M. Ligand selection for PET studies of D1 dopamine receptors. Relationship between distribution of binding sites and mRNA for DAARPP32 in the human brain. Clinical Neuropharmacology. 15: 466A-467A. PMID 1386781  0.423
1992 Hall H, Farde L, Halldin C, Högberg T, Larsson S, Sedvall G. Imaging of dopamine receptors using PET and SPECT. Neurochemistry International. 20: 329S-333S. PMID 1365450 DOI: 10.1016/0197-0186(92)90260-X  0.621
1992 Farde L, Nordström AL. PET analysis indicates atypical central dopamine receptor occupancy in clozapine-treated patients. The British Journal of Psychiatry. Supplement. 30-3. PMID 1358126 DOI: 10.1192/S0007125000296888  0.446
1992 Farde L, Nordström AL, Halldin C, Wiesel FA, Sedvall G. PET studies of dopamine receptors in relation to antipsychotic drug treatment. Clinical Neuropharmacology. 15: 468A-469A. PMID 1354052  0.563
1992 Farde L, Nordström AL, Wiesel FA, Pauli S, Halldin C, Sedvall G. Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects. Archives of General Psychiatry. 49: 538-44. PMID 1352677 DOI: 10.1001/Archpsyc.1992.01820070032005  0.58
1992 Halldin C, Farde L, Litton JE, Hall H, Sedvall G. [11C]Ro 15-4513, a ligand for visualization of benzodiazepine receptor binding. Preparation, autoradiography and positron emission tomography. Psychopharmacology. 108: 16-22. PMID 1329130 DOI: 10.1007/Bf02245279  0.668
1992 Pauli S, Liljequist S, Farde L, Swahn CG, Halldin C, Litton JE, Sedvall G. PET analysis of alcohol interaction with the brain disposition of [11C]flumazenil. Psychopharmacology. 107: 180-5. PMID 1319600 DOI: 10.1007/Bf02245135  0.59
1992 Farde L, Hall H. Positron emission tomography--examination of chemical transmission in the living human brain. Development of radioligands. Arzneimittel-Forschung. 42: 260-4. PMID 1316756  0.477
1992 SEDVALL G, FARDE L, NORDSTROM A. PET SCANNING OF DOPAMINE RECEPTORS AND PSYCHOSIS Behavioural Pharmacology. 3: 21. DOI: 10.1097/00008877-199204001-00061  0.591
1992 Nyberg S, Farde L, Halldin C, Eriksson B. PET Examination of Central D2 dopamine and 5-HT2 Receptor Occupancy by Risperidone Clinical Neuropharmacology. 15: 198B. DOI: 10.1097/00002826-199202001-00380  0.471
1992 Hall H, Farde L, Litton JE, Halldin C, Sedvall G. PET AND AUTORADIOGRAPHY OF BENZODIAZEPINE RECEPTOR BINDING WITH RADIOLABELLED FLUMAZENIL AND RO 15-4513. Clinical Neuropharmacology. 15: 29B. DOI: 10.1097/00002826-199202001-00054  0.62
1992 Nordström A, Farde L, Pauli S, Litton J, Halldin C. PET analysis of central [11C]raclopride binding in healthy young adults and schizophrenic patients-reliability and age effects Human Psychopharmacology: Clinical and Experimental. 7: 157-165. DOI: 10.1002/Hup.470070302  0.52
1992 Swahn CG, Farde L, Halldin C, Sedvall G. Ligand metabolites in plasma during PET-studies with the 11C-labelled dopamine antagonists, raclopride, SCH 23390 and N-methylspiroperidol Human Psychopharmacology. 7: 97-103. DOI: 10.1002/Hup.470070204  0.592
1991 Halldin C, Farde L, Högberg T, Hall H, Ström P, Ohlberger A, Solin O. A comparative PET-study of five carbon-11 or fluorine-18 labelled salicylamides. Preparation and in vitro dopamine D-2 receptor binding. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 18: 871-81. PMID 1839303 DOI: 10.1016/0883-2897(91)90096-4  0.507
1991 Sedvall G, Farde L, Barnett A, Hall H, Halldin C. 11C-SCH 39166, a selective ligand for visualization of dopamine-D1 receptor binding in the monkey brain using PET. Psychopharmacology. 103: 150-3. PMID 1674157 DOI: 10.1007/Bf02244195  0.685
1991 Hall H, Högberg T, Halldin C, Köhler C, Ström P, Ross SB, Larsson SA, Farde L. NCQ 298, a new selective iodinated salicylamide ligand for the labelling of dopamine D2 receptors. Psychopharmacology. 103: 6-18. PMID 1672460 DOI: 10.1007/Bf02244067  0.532
1991 Eriksson L, Farde L, Rosenquist G. Kinetic analysis of receptor binding with positron emission tomography. Acta Radiologica. Supplementum. 376: 126-7. PMID 1666746  0.332
1991 Halldin C, Farde L, Hall H, Högberg T, Printz G, Pulka W, Sedvall G, Solin O. Synthesis of five benzamide analogs. Comparison with positron emission tomography. Acta Radiologica. Supplementum. 376: 121-2. PMID 1666743  0.462
1991 Halldin C, Farde L, Barnett A, Sedvall G. Synthesis of carbon-11 labelled SCH 39166, a new selective dopamine D-1 receptor ligand, and preliminary PET investigations. International Journal of Radiation Applications and Instrumentation. Part a, Applied Radiation and Isotopes. 42: 451-5. PMID 1646191 DOI: 10.1016/0883-2889(91)90105-A  0.643
1991 Pauli S, Farde L, Halldin C, Sedvall G. Occupancy of the central benzodiazepine receptors during benzodiazepine treatment determined by PET European Neuropsychopharmacology. 1: 229-231. DOI: 10.1016/0924-977X(91)90498-J  0.593
1991 Sedval G, Farde L, Karlsson P, Nordström A, Chipkin R. PET studies of D1 and D2 dopamine receptors in drug naive schizophrenic patients European Neuropsychopharmacology. 1: 221-223. DOI: 10.1016/0924-977X(91)90495-G  0.482
1990 Halldin C, Farde L, Högberg T, Hall H, Sedvall G. Carbon-11 labelling of eticlopride in two different positions--a selective high-affinity ligand for the study of dopamine D-2 receptors using PET. International Journal of Radiation Applications and Instrumentation. Part a, Applied Radiation and Isotopes. 41: 669-74. PMID 2170298 DOI: 10.1016/0883-2889(90)90082-R  0.645
1990 Blomqvist G, Pauli S, Farde L, Eriksson L, Persson A, Halldin C. Maps of receptor binding parameters in the human brain--a kinetic analysis of PET measurements. European Journal of Nuclear Medicine. 16: 257-65. PMID 2112470 DOI: 10.1007/Bf00842777  0.519
1990 Wiesel FA, Farde L, Nordström AL, Sedvall G. Central D1- and D2-receptor occupancy during antipsychotic drug treatment. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 14: 759-67. PMID 1981395 DOI: 10.1016/0278-5846(90)90046-J  0.645
1990 Farde L, von Bahr C. Distribution of remoxipride to the human brain and central D2-dopamine receptor binding examined in vivo by PET. Acta Psychiatrica Scandinavica. Supplementum. 358: 67-71. PMID 1978494 DOI: 10.1111/j.1600-0447.1990.tb05292.x  0.502
1990 Hall H, Wedel I, Halldin C, Kopp J, Farde L. Comparison of the in vitro receptor binding properties of N-[3H]methylspiperone and [3H]raclopride to rat and human brain membranes. Journal of Neurochemistry. 55: 2048-57. PMID 1977888 DOI: 10.1111/J.1471-4159.1990.Tb05794.X  0.428
1990 Farde L, Wiesel FA, Stone-Elander S, Halldin C, Nordström AL, Hall H, Sedvall G. D2 dopamine receptors in neuroleptic-naive schizophrenic patients. A positron emission tomography study with [11C]raclopride. Archives of General Psychiatry. 47: 213-9. PMID 1968328 DOI: 10.1001/Archpsyc.1990.01810150013003  0.669
1990 Farde L, Nordstrom A, Wiesel F, Halldin C, Sedvall G. D1- and D2-dopamine receptor occupancy during treatment with classical and atypical neurpleptics Schizophrenia Research. 3: 51-52. DOI: 10.1016/0920-9964(90)90133-R  0.539
1989 Farde L, Wiesel FA, Nilsson L, Sedvall G. The potential of positron-emission tomography for pharmacokinetic and pharmacodynamic studies of neuroleptics. Psychopharmacology Series. 7: 32-9. PMID 2574454 DOI: 10.1007/978-3-642-74430-3_4  0.496
1989 Wiesel FA, Farde L, Halldin C. Clinical melperone treatment blocks D2-dopamine receptors in the human brain as determined by PET. Acta Psychiatrica Scandinavica. Supplementum. 352: 30-4. PMID 2573239 DOI: 10.1111/j.1600-0447.1989.tb06433.x  0.457
1989 Farde L, Wiesel FA, Nordström AL, Sedvall G. D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics. Psychopharmacology. 99: S28-31. PMID 2573104 DOI: 10.1007/BF00442555  0.627
1989 Farde L, Eriksson L, Blomquist G, Halldin C. Kinetic analysis of central [11C]raclopride binding to D2-dopamine receptors studied by PET--a comparison to the equilibrium analysis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 9: 696-708. PMID 2528555 DOI: 10.1038/Jcbfm.1989.98  0.568
1989 Halldin C, Högberg T, Stone-Elander S, Farde L, Hall H, Printz G, Solin O, Sedvall G. Synthesis of [ethyl-18F]fluororaclopride for the in vivo study of dopamine D2 receptors using PET Journal of Labelled Compounds and Radiopharmaceuticals. 26: 338-339. DOI: 10.1002/JLCR.25802601146  0.373
1989 Persson A, Pauli S, Halldin C, Stone-Elander S, Farde L, Sjögren I, Sedvall G. Saturation analysis of specific11C Ro 15-1788 binding to the human neocortex using positron emission tomography Human Psychopharmacology: Clinical and Experimental. 4: 21-31. DOI: 10.1002/Hup.470040105  0.649
1989 Farde L, Wiesel FA, Halldin C, Sedvall G, Nilsson L. Dopamine Receptor Occupancy and Plasma Haloperidol Levels-Reply Archives of General Psychiatry. 46: 483-484. DOI: 10.1001/Archpsyc.1989.01810050097022  0.586
1988 Farde L, Pauli S, Hall H, Eriksson L, Halldin C, Högberg T, Nilsson L, Sjögren I, Stone-Elander S. Stereoselective binding of 11C-raclopride in living human brain - a search for extrastriatal central D2-dopamine receptors by PET Psychopharmacology. 94: 471-478. PMID 3131792 DOI: 10.1007/Bf00212840  0.564
1988 Farde L, Wiesel FA, Jansson P, Uppfeldt G, Wahlen A, Sedvall G. An open label trial of raclopride in acute schizophrenia. Confirmation of D2-dopamine receptor occupancy by PET. Psychopharmacology. 94: 1-7. PMID 3126517 DOI: 10.1007/BF00735871  0.645
1988 Sedvall G, Farde L, Hall H, Pauli S, Persson A, Wiesel FA. PET scanning--a new tool in clinical psychopharmacology. Psychopharmacology Series. 5: 27-33. PMID 3045802 DOI: 10.1007/978-3-642-73280-5_3  0.692
1988 Hall H, Köhler C, Gawell L, Farde L, Sedvall G. Raclopride, a new selective ligand for the dopamine-D2 receptors. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 12: 559-68. PMID 2975809 DOI: 10.1016/0278-5846(88)90001-2  0.673
1988 Andreasen NC, Carson R, Diksic M, Evans A, Farde L, Gjedde A, Hakim A, Lal S, Nair N, Sedvall G. Workshop on schizophrenia, PET, and dopamine D2 receptors in the human neostriatum. Schizophrenia Bulletin. 14: 471-84. PMID 2975043 DOI: 10.1093/SCHBUL/14.3.471  0.655
1988 Hall H, Farde L, Sedvall G. Human dopamine receptor subtypes--in vitro binding analysis using 3H-SCH 23390 and 3H-raclopride. Journal of Neural Transmission. 73: 7-21. PMID 2969950 DOI: 10.1007/BF01244618  0.655
1988 Farde L, Grind M, Nilsson MI, Ogenstad S, Sedvall G. Remoxipride--a new potential antipsychotic drug. Pharmacological effects and pharmacokinetics following repeated oral administration in male volunteers. Psychopharmacology. 95: 157-61. PMID 2901121 DOI: 10.1007/BF00174501  0.481
1988 Farde L, Wiesel FA, Halldin C, Sedvall G. Central D2-dopamine receptor occupancy in schizophrenic patients treated with antipsychotic drugs. Archives of General Psychiatry. 45: 71-6. PMID 2892477 DOI: 10.1001/Archpsyc.1988.01800250087012  0.62
1988 Farde L. Brain Dopamine Receptors in Schizophrenia: PET Problems-Reply Archives of General Psychiatry. 45: 599. DOI: 10.1001/Archpsyc.1988.01800300097018  0.507
1987 Lindvall O, Backlund EO, Farde L, Sedvall G, Freedman R, Hoffer B, Nobin A, Seiger A, Olson L. Transplantation in Parkinson's disease: two cases of adrenal medullary grafts to the putamen. Annals of Neurology. 22: 457-68. PMID 3435067 DOI: 10.1002/Ana.410220403  0.492
1987 Farde L, Halldin C, Stone-Elander S, Sedvall G. PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride. Psychopharmacology. 92: 278-84. PMID 2957716 DOI: 10.1007/Bf00210831  0.682
1987 Sedvall G, Farde L, Wiesel FA. Quantitative determination of D2 dopamine receptor characteristics in healthy human subjects and psychiatric patients. Life Sciences. 41: 813-6. PMID 2956473 DOI: 10.1016/0024-3205(87)90169-X  0.605
1987 Farde L, Wiesel FA, Hall H, Halldin C, Stone-Elander S, Sedvall G. No D2 receptor increase in PET study of schizophrenia. Archives of General Psychiatry. 44: 671-2. PMID 2955770 DOI: 10.1001/Archpsyc.1987.01800190091013  0.659
1987 Sedvall G, Ehrin E, Farde L. Stereoselective binding of11C-labelled piquindone (Ro 22-1319) to dopamine-D2 receptors in the living human brain Human Psychopharmacology: Clinical and Experimental. 2: 23-30. DOI: 10.1002/HUP.470020105  0.7
1986 Halldin C, Stone-Elander S, Farde L, Ehrin E, Fasth KJ, LÃ¥ngström B, Sedvall G. Preparation of 11C-labelled SCH 23390 for the in vivo study of dopamine D-1 receptors using positron emission tomography. International Journal of Radiation Applications and Instrumentation. Part a, Applied Radiation and Isotopes. 37: 1039-43. PMID 3027000 DOI: 10.1016/0883-2889(86)90044-4  0.65
1986 Sedvall G, Farde L, Persson A, Wiesel FA. Imaging of neurotransmitter receptors in the living human brain. Archives of General Psychiatry. 43: 995-1005. PMID 3019270 DOI: 10.1001/Archpsyc.1986.01800100089012  0.601
1986 Sedvall G, Farde L, Stone-Elander S, Halldin C. Dopamine D1-receptor binding in the living human brain. Advances in Experimental Medicine and Biology. 204: 119-24. PMID 2947423 DOI: 10.1007/978-1-4684-5191-7_7  0.637
1986 Farde L, Hall H, Ehrin E, Sedvall G. Quantitative analysis of D2 dopamine receptor binding in the living human brain by PET. Science (New York, N.Y.). 231: 258-61. PMID 2867601 DOI: 10.1126/SCIENCE.2867601  0.69
1985 Ehrin E, Farde L, de Paulis T, Eriksson L, Greitz T, Johnström P, Litton JE, Nilsson JL, Sedvall G, Stone-Elander S. Preparation of 11C-labelled Raclopride, a new potent dopamine receptor antagonist: preliminary PET studies of cerebral dopamine receptors in the monkey. The International Journal of Applied Radiation and Isotopes. 36: 269-73. PMID 3874833 DOI: 10.1016/0020-708X(85)90083-3  0.67
1985 Farde L, Ehrin E, Eriksson L, Greitz T, Hall H, Hedström CG, Litton JE, Sedvall G. Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 82: 3863-7. PMID 3873656 DOI: 10.1073/PNAS.82.11.3863  0.701
1985 Persson A, Ehrin E, Eriksson L, Farde L, Hedström CG, Litton JE, Mindus P, Sedvall G. Imaging of [11C]-labelled Ro 15-1788 binding to benzodiazepine receptors in the human brain by positron emission tomography. Journal of Psychiatric Research. 19: 609-22. PMID 3001301 DOI: 10.1016/0022-3956(85)90080-9  0.66
1984 Widén L, Blomqvist G, DePaulis T, Ehrin E, Eriksson L, Farde L, Greitz T, Hedström CG, Ingvar DH, Litton JE, Nilsson JL, Ögren SO, Sedvall G, Stone-Slander S, Wiesel F-, et al. STUDIES OF SCHIZOPHRENIA WITH POSITRON CT Clinical Neuropharmacology. 7: S295. DOI: 10.1097/00002826-198406001-00266  0.496
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