Year |
Citation |
Score |
2024 |
Amador LA, Colón-Lorenzo EE, Rodríguez AD, Serrano AE. Probing the Antiplasmodial Properties of Plakortinic Acids C and D: An Uncommon Pair of Marine Peroxide-Polyketides Isolated from a Two-Sponge Association of and Collected near Puerto Rico. Life (Basel, Switzerland). 14. PMID 38929667 DOI: 10.3390/life14060684 |
0.385 |
|
2024 |
Rosado-Quiñones AM, Colón-Lorenzo EE, Pala ZR, Bosch J, Kudyba K, Kudyba H, Leed SE, Roncal N, Baerga-Ortiz A, Roche-Lima A, Gerena Y, Fidock DA, Roth A, Vega-Rodríguez J, Serrano AE. Novel hydrazone compounds with broad-spectrum antiplasmodial activity and synergistic interactions with antimalarial drugs. Antimicrobial Agents and Chemotherapy. e0164323. PMID 38639491 DOI: 10.1128/aac.01643-23 |
0.688 |
|
2020 |
Colón-Lorenzo EE, Colón-López DD, Vega-Rodríguez J, Dupin A, Fidock DA, Baerga-Ortiz A, Ortiz JG, Bosch J, Serrano AE. Structure-Based Screening of Glutathione S-Transferase Identifies CB-27 as a Novel Antiplasmodial Compound. Frontiers in Pharmacology. 11: 246. PMID 32256353 DOI: 10.3389/Fphar.2020.00246 |
0.685 |
|
2016 |
Padín-Irizarry V, Colón-Lorenzo EE, Vega-Rodríguez J, Castro MD, González-Méndez R, Ayala-Peña S, Serrano AE. Glutathione-deficient Plasmodium berghei parasites exhibit growth delay and nuclear DNA damage. Free Radical Biology & Medicine. 95: 43-54. PMID 26952808 DOI: 10.1016/J.Freeradbiomed.2016.02.032 |
0.682 |
|
2015 |
Rijpma SR, van der Velden M, González-Pons M, Annoura T, van Schaijk BC, van Gemert GJ, van den Heuvel JJ, Ramesar J, Chevalley-Maurel S, Ploemen IH, Khan SM, Franetich JF, Mazier D, de Wilt JH, Serrano AE, et al. Multidrug ABC transporters are essential for hepatic development of Plasmodium sporozoites. Cellular Microbiology. PMID 26332724 DOI: 10.1111/Cmi.12517 |
0.495 |
|
2015 |
Vega-Rodríguez J, Pastrana-Mena R, Crespo-Lladó KN, Ortiz JG, Ferrer-Rodríguez I, Serrano AE. Implications of Glutathione Levels in the Plasmodium berghei Response to Chloroquine and Artemisinin. Plos One. 10: e0128212. PMID 26010448 DOI: 10.1371/Journal.Pone.0128212 |
0.7 |
|
2014 |
Comer E, Beaudoin JA, Kato N, Fitzgerald ME, Heidebrecht RW, Lee Md, Masi D, Mercier M, Mulrooney C, Muncipinto G, Rowley A, Crespo-Llado K, Serrano AE, Lukens AK, Wiegand RC, et al. Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents. Journal of Medicinal Chemistry. 57: 8496-502. PMID 25211597 DOI: 10.1021/Jm500994N |
0.386 |
|
2014 |
le Roux D, Burger PB, Niemand J, Grobler A, Urbán P, Fernàndez-Busquets X, Barker RH, Serrano AE, I Louw A, Birkholtz LM. Novel S-adenosyl-L-methionine decarboxylase inhibitors as potent antiproliferative agents against intraerythrocytic Plasmodium falciparum parasites. International Journal For Parasitology. Drugs and Drug Resistance. 4: 28-36. PMID 24596666 DOI: 10.1016/J.Ijpddr.2013.11.003 |
0.516 |
|
2011 |
Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH, Dvorin JD, et al. Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors. Chemistry & Biology. 18: 1602-10. PMID 22195562 DOI: 10.1016/J.Chembiol.2011.09.016 |
0.513 |
|
2011 |
Gerena Y, Gonzalez-Pons M, Serrano AE. Cytofluorometric detection of rodent malaria parasites using red-excited fluorescent dyes Cytometry Part A. 79: 965-972. PMID 22015734 DOI: 10.1002/Cyto.A.21119 |
0.411 |
|
2011 |
Barker RH, Urgaonkar S, Mazitschek R, Celatka C, Skerlj R, Cortese JF, Tyndall E, Liu H, Cromwell M, Sidhu AB, Guerrero-Bravo JE, Crespo-Llado KN, Serrano AE, Lin JW, Janse CJ, et al. Aminoindoles, a novel scaffold with potent activity against Plasmodium falciparum. Antimicrobial Agents and Chemotherapy. 55: 2612-22. PMID 21422215 DOI: 10.1128/Aac.01714-10 |
0.372 |
|
2010 |
Urgaonkar S, Cortese JF, Barker RH, Cromwell M, Serrano AE, Wirth DF, Clardy J, Mazitschek R. A concise silylamine approach to 2-amino-3-hydroxy-indoles with potent in vivo antimalaria activity. Organic Letters. 12: 3998-4001. PMID 20718474 DOI: 10.1021/Ol101566H |
0.341 |
|
2010 |
Booker ML, Bastos CM, Kramer ML, Barker RH, Skerlj R, Sidhu AB, Deng X, Celatka C, Cortese JF, Guerrero Bravo JE, Crespo Llado KN, Serrano AE, Angulo-Barturen I, Jiménez-DÃaz MB, Viera S, et al. Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model. The Journal of Biological Chemistry. 285: 33054-64. PMID 20702404 DOI: 10.1074/Jbc.M110.162081 |
0.424 |
|
2010 |
Pastrana-Mena R, Dinglasan RR, Franke-Fayard B, Vega-Rodríguez J, Fuentes-Caraballo M, Baerga-Ortiz A, Coppens I, Jacobs-Lorena M, Janse CJ, Serrano AE. Glutathione reductase-null malaria parasites have normal blood stage growth but arrest during development in the mosquito Journal of Biological Chemistry. 285: 27045-27056. PMID 20573956 DOI: 10.1074/Jbc.M110.122275 |
0.719 |
|
2010 |
Colón-Lorenzo EE, Serrano AE, Nicholas HB, Wymore T, Ropelewski AJ, González-Méndez R. The plasmodium glutathione S-transferase: Bioinformatics characterization and classification into the sigma class Bioinformatics 2010 - Proceedings of the 1st International Conference On Bioinformatics. 173-180. |
0.302 |
|
2009 |
Vega-Rodríguez J, Franke-Fayard B, Dinglasan RR, Janse CJ, Pastrana-Mena R, Waters AP, Coppens I, Rodríguez-Orengo JF, Jacobs-Lorena M, Serrano AE. The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission Plos Pathogens. 5. PMID 19229315 DOI: 10.1371/Journal.Ppat.1000302 |
0.707 |
|
2009 |
González-Pons M, Szeto AC, González-Méndez R, Serrano AE. Identification and bioinformatic characterization of a multidrug resistance associated protein (ABCC) gene in Plasmodium berghei. Malaria Journal. 8: 1. PMID 19118502 DOI: 10.1186/1475-2875-8-1 |
0.383 |
|
2004 |
Ferrer-RodrÃguez I, Pérez-Rosado J, Gervais GW, Peters W, Robinson BL, Serrano AE. Plasmodium yoelii: identification and partial characterization of an MDR1 gene in an artemisinin-resistant line. The Journal of Parasitology. 90: 152-60. PMID 15040683 DOI: 10.1645/Ge-3225 |
0.424 |
|
2004 |
Szeto AC, Pérez-Rosado J, Ferrer-RodrÃguez I, Vega J, Torruella-Thillet C, Serrano AE. Identification and expression analysis of ABC genes in Plasmodium yoelii and P. berghei. Parasitology Research. 92: 1-11. PMID 14564508 DOI: 10.1007/S00436-003-1001-8 |
0.331 |
|
2002 |
Pérez-Rosado J, Gervais GW, Ferrer-RodrÃguez I, Peters W, Serrano AE. Plasmodium berghei: analysis of the gamma-glutamylcysteine synthetase gene in drug-resistant lines. Experimental Parasitology. 101: 175-82. PMID 12594957 DOI: 10.1016/S0014-4894(02)00138-8 |
0.502 |
|
2000 |
Carrasquilla G, Banguero M, Sanchez P, Carvajal F, Barker RH, Gervais GW, Algarin E, Serrano AE. Epidemiologic tools for malaria surveillance in an urban setting of low endemicity along the Colombian Pacific coast. The American Journal of Tropical Medicine and Hygiene. 62: 132-7. PMID 10761738 DOI: 10.4269/Ajtmh.2000.62.132 |
0.352 |
|
1999 |
Ferrer-Rodríguez I, Vázquez GJ, Córdova GJ, Serrano AE. Diagnosis of malaria by polymerase chain reaction Puerto Rico Health Sciences Journal. 18: 99-103. PMID 10461315 |
0.32 |
|
1999 |
Serrano AE, Robinson BL, Peters W, Trujillo-Nevárez K. Plasmodium berghei and Plasmodium yoelii: Molecular karyotypes of drug- resistant lines Experimental Parasitology. 91: 93-96. PMID 9920047 DOI: 10.1006/Expr.1999.4345 |
0.393 |
|
1999 |
Gervais GW, Trujillo K, Robinson BL, Peters W, Serrano AE. Plasmodium berghei: Identification of an mdr-like gene associated with drug resistance Experimental Parasitology. 91: 86-92. PMID 9920046 DOI: 10.1006/Expr.1999.4344 |
0.388 |
|
1989 |
Wilson CM, Serrano AE, Wasley A, Bogenschutz MP, Shankar AH, Wirth DF. Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum Science. 244: 1184-1186. PMID 2658061 DOI: 10.1126/Science.2658061 |
0.45 |
|
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