| Year |
Citation |
Score |
| 2024 |
O'Hare P, Cooney T, de Blank P, Gutmann DH, Kieran M, Milde T, Fangusaro J, Fisher M, Avula S, Packer R, Fukuoka K, Mankad K, Mueller S, Waanders AJ, Opocher E, ... ... Raabe E, et al. Resistance, rebound, and recurrence regrowth patterns in pediatric low-grade glioma treated by MAPK inhibition: A modified Delphi approach to build international consensus-based definitions-International Pediatric Low-Grade Glioma Coalition. Neuro-Oncology. PMID 38743009 DOI: 10.1093/neuonc/noae074 |
0.323 |
|
| 2024 |
Duchatel RJ, Jackson ER, Parackal SG, Kiltschewskij D, Findlay IJ, Mannan A, Staudt DE, Thomas BC, Germon ZP, Laternser S, Kearney PS, Jamaluddin MFB, Douglas AM, Beitaki TS, McEwen HP, ... ... Raabe EH, et al. PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma. The Journal of Clinical Investigation. PMID 38319732 DOI: 10.1172/JCI170329 |
0.317 |
|
| 2023 |
Sun CX, Daniel P, Bradshaw G, Shi H, Loi M, Chew N, Parackal S, Tsui V, Liang Y, Koptyra M, Adjumain S, Sun C, Chong WC, Fernando D, Drinkwater C, ... ... Raabe EH, et al. Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities. Cancer Cell. PMID 37001527 DOI: 10.1016/j.ccell.2023.03.007 |
0.331 |
|
| 2022 |
Parkhurst A, Wang SZ, Findlay TR, Malebranche KJ, Odabas A, Alt J, Maxwell MJ, Kaur H, Peer CJ, Figg WD, Warren KE, Slusher BS, Eberhart CG, Raabe EH, Rubens JA. Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors. Cell Death & Disease. 13: 410. PMID 35484114 DOI: 10.1038/s41419-022-04868-9 |
0.338 |
|
| 2022 |
Pham K, Hanaford AR, Poore BA, Maxwell MJ, Sweeney H, Parthasarathy A, Alt J, Rais R, Slusher BS, Eberhart CG, Raabe EH. Comprehensive Metabolic Profiling of MYC-Amplified Medulloblastoma Tumors Reveals Key Dependencies on Amino Acid, Tricarboxylic Acid and Hexosamine Pathways. Cancers. 14. PMID 35267619 DOI: 10.3390/cancers14051311 |
0.339 |
|
| 2021 |
Maxwell MJ, Arnold A, Sweeney H, Chen L, Lih TM, Schnaubelt M, Eberhart CG, Rubens JA, Zhang H, Clark DJ, Raabe EH. Unbiased proteomic and phosphoproteomic analysis identifies response signatures and novel susceptibilities after combined MEK and mTOR inhibition in BRAF mutant glioma. Molecular & Cellular Proteomics : McP. 100123. PMID 34298159 DOI: 10.1016/j.mcpro.2021.100123 |
0.308 |
|
| 2021 |
Nakata S, Yuan M, Rubens JA, Kahlert UD, Maciaczyk J, Raabe EH, Eberhart CG. BCOR Internal Tandem Duplication Expression in Neural Stem Cells Promotes Growth, Invasion, and Expression of PRC2 Targets. International Journal of Molecular Sciences. 22. PMID 33920124 DOI: 10.3390/ijms22083913 |
0.352 |
|
| 2021 |
Pham K, Maxwell MJ, Sweeney H, Alt J, Rais R, Eberhart CG, Slusher BS, Raabe EH. Novel Glutamine Antagonist JHU395 Suppresses MYC-Driven Medulloblastoma Growth and Induces Apoptosis. Journal of Neuropathology and Experimental Neurology. PMID 33712838 DOI: 10.1093/jnen/nlab018 |
0.304 |
|
| 2021 |
Maynard R, Poore B, Hanaford AR, Pham K, James M, Alt J, Park Y, Slusher BS, Tamayo P, Mesirov J, Archer TC, Pomeroy S, Eberhart CG, Raabe EH. TORC1/2 kinase inhibition depletes glutathione and synergizes with carboplatin to suppress the growth of MYC-driven medulloblastoma. Cancer Letters. PMID 33571541 DOI: 10.1016/j.canlet.2021.02.001 |
0.408 |
|
| 2020 |
Garcia-Moure M, Gonzalez-Huarriz M, Labiano S, Guruceaga E, Bandres E, Zalacain M, Marrodan L, de Andrea CE, Villalba Esparza M, Martínez-Vélez N, Laspidea V, Puigdelloses M, Gallego Perez-Larraya J, Iñigo-Marco I, Stripecke R, ... ... Raabe EH, et al. Delta-24-RGD, an oncolytic adenovirus, increases survival and promotes proinflammatory immune landscape remodeling in models of AT/RT and CNS-PNET. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33376098 DOI: 10.1158/1078-0432.CCR-20-3313 |
0.317 |
|
| 2020 |
Shahab S, Rubens J, Kaur H, Sweeney H, Eberhart CG, Raabe EH. MEK Inhibition Suppresses Growth of Atypical Teratoid/Rhabdoid Tumors. Journal of Neuropathology and Experimental Neurology. PMID 32472116 DOI: 10.1093/Jnen/Nlaa042 |
0.475 |
|
| 2020 |
Negron K, Zhu C, Chen SW, Shahab S, Rao D, Raabe EH, Eberhart CG, Hanes J, Suk JS. Non-adhesive and highly stable biodegradable nanoparticles that provide widespread and safe transgene expression in orthotopic brain tumors. Drug Delivery and Translational Research. PMID 32323162 DOI: 10.1007/S13346-020-00759-8 |
0.383 |
|
| 2020 |
Meel MH, de Gooijer MC, Metselaar DS, Sewing ACP, Zwaan K, Waranecki P, Breur M, Buil LCM, Lagerweij T, Wedekind LE, Twisk JWR, Koster J, Hashizume R, Raabe EH, Montero-Carcaboso A, et al. Combined therapy of AXL and HDAC inhibition reverses mesenchymal transition in diffuse intrinsic pontine glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32165429 DOI: 10.1158/1078-0432.Ccr-19-3538 |
0.415 |
|
| 2020 |
Kaur H, Guo H, White D, Green P, Hector AM, Akhtarkhavari S, Bhargava A, Shah S, Eberhart CG, Mumm J, Raabe EH. Abstract A38: Validation of potential therapies for treatment of fatal pediatric brain tumors DIPG and AT/RT using a novel rapid intracranial model in zebrafish Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-A38 |
0.508 |
|
| 2020 |
Parkhurst A, Wang S, Kaur H, Arnold A, Eberhart C, Raabe E, Rubens J. Abstract 6226: Sapanisertib interferes with the NRF2-mediated stress response to synergize with Obatoclax and extend AT/RT survival Cancer Research. 80: 6226-6226. DOI: 10.1158/1538-7445.Am2020-6226 |
0.419 |
|
| 2020 |
Guo H, Kaur H, Eberhart CG, Raabe EH. Abstract 4943: The stem cell factor LIN28B regulates proliferation and apoptosis in diffuse intrinsic pontine glioma Cancer Research. 80: 4943-4943. DOI: 10.1158/1538-7445.Am2020-4943 |
0.514 |
|
| 2020 |
Parkhurst A, Park Y, Arnold A, Koldobskiy M, Eberhart C, Raabe E, Rubens J. Abstract 3904: The novel combination of PAC-1 and ONC201 circumvent H3K27M-driven pro-survival gene expression to induce DIPG cell death Tumor Biology. DOI: 10.1158/1538-7445.Am2020-3904 |
0.33 |
|
| 2019 |
Arnold A, Yuan M, Price A, Harris L, Eberhart CG, Raabe EH. Synergistic activity of mTORC1/2 kinase and MEK inhibitors suppresses pediatric low-grade glioma tumorigenicity and vascularity. Neuro-Oncology. PMID 31841591 DOI: 10.1093/Neuonc/Noz230 |
0.392 |
|
| 2019 |
Martin AM, Bell WR, Yuan M, Harris L, Poore B, Arnold A, Engle EL, Asnaghi L, Lim M, Raabe EH, Eberhart CG. PD-L1 Expression in Pediatric Low-Grade Gliomas Is Independent of BRAF V600E Mutational Status. Journal of Neuropathology and Experimental Neurology. PMID 31819973 DOI: 10.1093/Jnen/Nlz119 |
0.327 |
|
| 2019 |
Lin GL, Wilson KM, Ceribelli M, Stanton BZ, Woo PJ, Kreimer S, Qin EY, Zhang X, Lennon J, Nagaraja S, Morris PJ, Quezada M, Gillespie SM, Duveau DY, Michalowski AM, ... ... Raabe EH, et al. Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening. Science Translational Medicine. 11. PMID 31748226 DOI: 10.1126/Scitranslmed.Aaw0064 |
0.339 |
|
| 2019 |
Hanaford AR, Alt J, Rais R, Wang SZ, Kaur H, Thorek DLJ, Eberhart CG, Slusher BS, Martin AM, Raabe EH. Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma. Translational Oncology. 12: 1314-1322. PMID 31340195 DOI: 10.1016/J.Tranon.2019.05.013 |
0.477 |
|
| 2019 |
Wang SZ, Poore B, Alt J, Price A, Allen SJ, Hanaford AR, Kaur H, Orr BA, Slusher BS, Eberhart CG, Raabe EH, Rubens JA. Unbiased metabolic profiling predicts sensitivity of high MYC-expressing atypical teratoid/rhabdoid tumors to glutamine inhibition with 6-diazo-5-oxo-L-norleucine. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31300448 DOI: 10.1158/1078-0432.Ccr-19-0189 |
0.474 |
|
| 2019 |
Martínez-Vélez N, Garcia-Moure M, Marigil M, González-Huarriz M, Puigdelloses M, Gallego Pérez-Larraya J, Zalacaín M, Marrodán L, Varela-Guruceaga M, Laspidea V, Aristu JJ, Ramos LI, Tejada-Solís S, Díez-Valle R, Jones C, ... ... Raabe E, et al. The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models. Nature Communications. 10: 2235. PMID 31138805 DOI: 10.1038/S41467-019-10043-0 |
0.434 |
|
| 2019 |
Natsumeda M, Liu Y, Nakata S, Miyahara H, Hanaford A, Ahsan S, Stearns D, Skuli N, Kahlert UD, Raabe EH, Rodriguez FJ, Eberhart CG. Inhibition of enhancer of zest homologue 2 is a potential therapeutic target for high-MYC medulloblastoma. Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 30632221 DOI: 10.1111/Neup.12534 |
0.405 |
|
| 2019 |
Wang SZ, Poore B, Alt J, Price A, Allen S, Orr B, Rais R, Slusher B, Eberhart C, Raabe EH, Rubens JH. Abstract 5267: Unbiased metabolic profiling of atypical teratoid/rhabdoid tumors predicts sensitivity to the glutamine metabolic inhibitor 6-diazo-5-oxo-L-norleucine Cancer Research. 79: 5267-5267. DOI: 10.1158/1538-7445.Sabcs18-5267 |
0.458 |
|
| 2019 |
Arnold A, Harris L, Yuan M, Rodriguez F, Eberhart C, Raabe E. Abstract 3108: Inhibition of the mTOR and MAPK pathways suppresses growth, induces apoptosis, and decreases vascularity in pediatric low grade glioma Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3108 |
0.358 |
|
| 2019 |
Kaur H, Guo H, Green P, Akhtarkhavari S, Shah S, Eberhart CG, Raabe EH. Abstract 2888: Targeting the fatal pediatric brain tumors AT/RT and DIPG with the DNA binding agent quinacrine Cancer Research. 79: 2888-2888. DOI: 10.1158/1538-7445.Sabcs18-2888 |
0.501 |
|
| 2019 |
Shahab S, Rubens J, Eberhart C, Raabe E. Abstract 3120: The novel MEK inhibitor binimetinib decreases cell growth and induces apoptosis in AT/RT Cancer Research. 79: 3120-3120. DOI: 10.1158/1538-7445.Am2019-3120 |
0.503 |
|
| 2019 |
Arnold A, Harris L, Yuan M, Rodriguez F, Eberhart C, Raabe E. PDTM-18. COMBINED SUPPRESSION OF THE mTOR AND MAPK PATHWAYS INHIBITS GROWTH, DECREASES VASCULARITY AND INDUCES APOPTOSIS OR SENESCENCE IN PEDIATRIC LOW GRADE GLIOMA Neuro-Oncology. 21: vi191-vi191. DOI: 10.1093/Neuonc/Noz175.794 |
0.481 |
|
| 2019 |
Arnold A, Harris L, Yuan M, Rodriguez F, Eberhart C, Raabe E. LGG-15. COMBINED SUPPRESSION OF THE MTOR AND MAPK PATHWAYS INHIBITS CELL PROLIFERATION AND DECREASES VASCULARITY IN PEDIATRIC LOW GRADE GLIOMA Neuro-Oncology. 21: ii102-ii102. DOI: 10.1093/Neuonc/Noz036.158 |
0.409 |
|
| 2019 |
Kaur H, Guo H, Akhtarkhavari S, Eberhart C, Raabe E. HGG-25. TARGETING THE EPIGENETIC MODIFIER HMGA2 IN DIPG AND HIGH GRADE GLIOMAS INHIBITS PROLIFERATION, INVASION AND TUMORIGENICITY Neuro-Oncology. 21: ii92-ii92. DOI: 10.1093/Neuonc/Noz036.119 |
0.381 |
|
| 2019 |
Shahab S, Rubens J, Eberhart C, Raabe E. ATRT-12. BINIMETINIB SUPPRESSES THE GROWTH OF ATYPICAL TERATOID/RHABDOID TUMOR CELLS AND INDUCES APOPOTOSIS Neuro-Oncology. 21: ii65-ii65. DOI: 10.1093/Neuonc/Noz036.011 |
0.44 |
|
| 2019 |
Wang S, Poore B, Alt J, Price A, Allen S, Orr B, Rais R, Slusher B, Eberhart C, Raabe E, Rubens J. ATRT-04. UNBIASED METABOLIC PROFILING OF ATYPICAL TERATOID/RHABDOID TUMORS PREDICTS SENSITIVITY TO GLUTAMINE METABOLIC INHIBITORS Neuro-Oncology. 21: ii63-ii63. DOI: 10.1093/Neuonc/Noz036.003 |
0.34 |
|
| 2018 |
Tantravedi S, Vesuna F, Winnard PT, Martin A, Lim M, Eberhart CG, Berlinicke C, Raabe E, van Diest PJ, Raman V. Targeting DDX3 in Medulloblastoma Using the Small Molecule Inhibitor RK-33. Translational Oncology. 12: 96-105. PMID 30292066 DOI: 10.1016/J.Tranon.2018.09.002 |
0.463 |
|
| 2018 |
Poore B, Yuan M, Arnold A, Price A, Alt J, Rubens JA, Slusher BS, Eberhart CG, Raabe EH. mTORC1 inhibition in pediatric low-grade glioma depletes glutathione and therapeutically synergizes with carboplatin. Neuro-Oncology. PMID 30239952 DOI: 10.1093/Neuonc/Noy150 |
0.44 |
|
| 2018 |
Brosnan-Cashman JA, Yuan M, Graham MK, Rizzo AJ, Myers KM, Davis C, Zhang R, Esopi DM, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner. Plos One. 13: e0204159. PMID 30226859 DOI: 10.1371/Journal.Pone.0204159 |
0.375 |
|
| 2018 |
Nix JS, Haffner MC, Ahsan S, Hicks J, De Marzo AM, Blakeley J, Raabe EH, Rodriguez FJ. Malignant Peripheral Nerve Sheath Tumors Show Decreased Global DNA Methylation. Journal of Neuropathology and Experimental Neurology. PMID 30169729 DOI: 10.1093/Jnen/Nly076 |
0.36 |
|
| 2018 |
Meel MH, de Gooijer MC, Guillén Navarro M, Waranecki P, Breur M, Buil L, Wedekind LE, Twisk JWR, Koster J, Hashizume R, Raabe EH, Montero Carcaboso A, Bugiani M, van Tellingen O, van Vuurden DG, et al. MELK inhibition in Diffuse Intrinsic Pontine Glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30061363 DOI: 10.1158/1078-0432.Ccr-18-0924 |
0.41 |
|
| 2018 |
Martin AM, Nirschl CJ, Polanczyk MJ, Bell WR, Nirschl TR, Harris-Bookman S, Phallen J, Hicks J, Martinez D, Ogurtsova A, Xu H, Sullivan LM, Meeker AK, Raabe EH, Cohen KJ, et al. PD-L1 expression in medulloblastoma: an evaluation by subgroup. Oncotarget. 9: 19177-19191. PMID 29721192 DOI: 10.18632/Oncotarget.24951 |
0.312 |
|
| 2018 |
Casaos J, Huq S, Lott T, Felder R, Choi J, Gorelick N, Peters M, Xia Y, Maxwell R, Zhao T, Ji C, Simon T, Sesen J, Scotland SJ, Kast RE, ... ... Raabe E, et al. Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors. Oncotarget. 9: 8054-8067. PMID 29487714 DOI: 10.18632/Oncotarget.23883 |
0.493 |
|
| 2018 |
Brosnan-Cashman JA, Graham MK, Rizzo AJ, Myers K, Zhang R, Göger E, Zarinshenas R, Davis C, Yuan M, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract B14: Establishment and characterization of in vitro models of alternative lengthening of telomeres (ALT) in pediatric high-grade glioma Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-B14 |
0.397 |
|
| 2018 |
Guo H, Kaur H, Akhtarkhavari S, Eberhart CG, Raabe EH. Abstract 4850: The minor groove binding agent quinacrine inhibits growth and increases apoptotic death in diffuse intrinsic pontine glioma tumor cells Cancer Research. 78: 4850-4850. DOI: 10.1158/1538-7445.Am2018-4850 |
0.493 |
|
| 2018 |
Arnold A, Yuan M, Rodriguez FJ, Eberhart CG, Raabe EH. Abstract 4629: Synergistic growth inhibitor effect on a patient derived NF1 pilocytic astrocytoma cell line with the dual mTORC1/2 inhibitor TAK228 and MEK inhibitor trametinib Cancer Research. 78: 4629-4629. DOI: 10.1158/1538-7445.Am2018-4629 |
0.483 |
|
| 2018 |
Maxwell MJ, Poore B, Hanaford A, Alt J, Rais R, Slusher BS, Eberhart CG, Raabe EH. Abstract 3521: Glutamine metabolic inhibition synergizes with L-asparaginase in MYCN-amplified neuroblastoma Cancer Research. 78: 3521-3521. DOI: 10.1158/1538-7445.Am2018-3521 |
0.464 |
|
| 2018 |
Wang SZ, Poore B, Alt J, Rais R, Allen S, Orr B, Slusher B, Eberhart C, Raabe E, Rubens J. Abstract 3519: Disrupting glutamine metabolism depletes glutathione and sensitizes atypical teratoid/rhabdoid tumor to carboplatin Cancer Research. 78: 3519-3519. DOI: 10.1158/1538-7445.Am2018-3519 |
0.499 |
|
| 2018 |
Park Y, An P, Ding D, Eberhart CG, Raabe EH. Abstract 3182: A human neural stem cell glial brain tumor model identifies the relative contribution of different oncogenic elements to malignant transformation Cancer Research. 78: 3182-3182. DOI: 10.1158/1538-7445.Am2018-3182 |
0.449 |
|
| 2018 |
Arnold A, Yuan M, Rodriguez F, Eberhart C, Raabe E. PDCT-02. COMBINED INHIBITION OF MTORC1/C2 AND MEK PATHWAY IS SYNERGISTIC IN PRECLINICAL TESTING OF PEDIATRIC LOW-GRADE GLIOMA INCLUDING A NOVEL PATIENT-DERIVED NF1 PILOCYTIC ASTROCYTOMA CELL LINE Neuro-Oncology. 20: vi200-vi201. DOI: 10.1093/Neuonc/Noy148.832 |
0.401 |
|
| 2018 |
Hanaford A, Poore B, Alt J, Slusher B, Eberhart C, Raabe E. Mbrs-61. In Vivo Metabolomics Reveals A Potent Combination Therapy For Myc-Driven Medulloblastoma Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.505 |
0.304 |
|
| 2018 |
Maynard R, Hanaford A, Poore B, Rubens J, Archer T, Tamayo P, Pomeroy S, Eberhart C, Raabe E. MBRS-30. TORC1/2 INHIBITION SENSITIZES MYC-DRIVEN MEDULLOBLASTOMA CELLS TO CARBOPLATIN CHEMOTHERAPY Neuro-Oncology. 20: i134-i135. DOI: 10.1093/Neuonc/Noy059.475 |
0.369 |
|
| 2018 |
Arnold A, Yuan M, Rodriguez F, Eberhart C, Raabe E. LGG-52. DUAL INHIBITION OF mTORC1/C2 AND MEK PATHWAY IS SYNERGISTIC IN MULTIPLE HUMAN MODELS OF PEDIATRIC LOW-GRADE GLIOMA INCLUDING A NOVEL PATIENT-DERIVED NF1 PILOCYTIC ASTROCYTOMA CELL LINE Neuro-Oncology. 20: i115-i116. DOI: 10.1093/Neuonc/Noy059.393 |
0.406 |
|
| 2018 |
Poore B, Yuan M, Arnold A, Price A, Alt J, Rubens J, Slusher B, Eberhart C, Raabe E. Lgg-51. Metabolic Profiling In Pediatric Low Grade Glioma Identifies Glutathione Depletion After Mtorc1 Inhibition And Validates Everolimus And Carboplatin As A Potential Combination Therapy Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.392 |
0.355 |
|
| 2018 |
Shah S, Rubens J, Eberhart C, Raabe E. DIPG-62. CARBOPLATIN SYNERGIZES WITH BCL-2 INHIBITOR TO POTENTIATE KILLING OF DIPG CELLS Neuro-Oncology. 20: i61-i61. DOI: 10.1093/Neuonc/Noy059.155 |
0.356 |
|
| 2018 |
Shah S, Rubens J, Eberhart C, Raabe E. DIPG-61. HISTONE DEACETYLASE INHIBITOR PANOBINOSTAT SYNERGIZES WITH DUAL MTOR INHIBITOR TAK228 TO POTENTIATE KILLING OF DIPG CELLS Neuro-Oncology. 20: i61-i61. DOI: 10.1093/Neuonc/Noy059.154 |
0.321 |
|
| 2018 |
Park Y, An P, Ding D, Eberhart CG, Raabe EH. DIPG-34. A HUMAN NEURAL STEM CELL DIPG MODEL IDENTIFIES THE RELATIVE CONTRIBUTION OF DIFFERENT ONCOGENIC ELEMENTS TO INVASIVE MALIGNANT TRANSFORMATION Neuro-Oncology. 20: i55-i56. DOI: 10.1093/Neuonc/Noy059.127 |
0.317 |
|
| 2018 |
Meel M, Gooijer Md, Navarro MG, Waranecki P, Breur M, Buil L, Wedekind L, Twisk J, Koster J, Hashizume R, Raabe E, Carcaboso ÁM, Bugiani M, Tellingen Ov, Vuurden Dv, et al. Dipg-05. Preclinical Efficacy Of Melk Inhibition In Diffuse Intrinsic Pontine Glioma Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.099 |
0.318 |
|
| 2018 |
Meel M, Gooijer Md, Zwaan K, Waranecki P, Breur M, Buil L, Lagerweij T, Wedekind L, Twisk J, Koster J, Hashizume R, Raabe E, Carcaboso ÁM, Bugiani M, Tellingen Ov, et al. Dipg-04. Inhibition Of Axl Sensitizes Diffuse Intrinsic Pontine Glioma To Cytotoxic Therapies Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.098 |
0.324 |
|
| 2018 |
Shahab S, Rubens J, Eberhart C, Raabe E. ATRT-37. TARGETING ATYPICAL TERATOID/RHABDOID TUMOR USING MATURE LET-7 LEADS TO INCREASED APOPTOSIS Neuro-Oncology. 20: i35-i36. DOI: 10.1093/Neuonc/Noy059.034 |
0.405 |
|
| 2018 |
Kaur H, Guo H, Shah S, Akhtarkhavari S, Eberhart C, Raabe E. ATRT-33. TARGETING THE LETHAL PEDIATRIC TUMORS ATRT AND DIPG WITH THE DNA MINOR-GROOVE BINDING AGENT QUINACRINE Neuro-Oncology. 20: i34-i35. DOI: 10.1093/Neuonc/Noy059.030 |
0.351 |
|
| 2017 |
Semenkow S, Li S, Kahlert UD, Raabe EH, Xu J, Arnold A, Janowski M, Oh BC, Brandacher G, Bulte JWM, Eberhart CG, Walczak P. An immunocompetent mouse model of human glioblastoma. Oncotarget. 8: 61072-61082. PMID 28977847 DOI: 10.18632/Oncotarget.17851 |
0.41 |
|
| 2017 |
Rubens JA, Wang SZ, Price A, Weingart MF, Allen SJ, Orr BA, Eberhart CG, Raabe EH. The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity. Neuro-Oncology. PMID 28582547 DOI: 10.1093/Neuonc/Nox067 |
0.473 |
|
| 2017 |
Miyahara H, Yadavilli S, Natsumeda M, Rubens J, Rodgers L, Kambhampati M, Taylor I, Kaur H, Asnaghi L, Eberhart CG, Warren KE, Nazarian J, Raabe EH. The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma. Cancer Letters. PMID 28450157 DOI: 10.1016/J.Canlet.2017.04.019 |
0.485 |
|
| 2017 |
Gholamin S, Mitra SS, Feroze AH, Liu J, Kahn SA, Zhang M, Esparza R, Richard C, Ramaswamy V, Remke M, Volkmer AK, Willingham S, Ponnuswami A, McCarty A, Lovelace P, ... ... Raabe EH, et al. Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors. Science Translational Medicine. 9. PMID 28298418 DOI: 10.1126/Scitranslmed.Aaf2968 |
0.403 |
|
| 2017 |
Arnold A, Rodriguez F, Eberhart CG, Raabe EH. Abstract 703: Combinatory treatment for pediatric low grade glioma with the dual mTORC1/2 inhibitor TAK228 and MEK inhibitor Trametinib Cancer Research. 77: 703-703. DOI: 10.1158/1538-7445.Am2017-703 |
0.492 |
|
| 2017 |
Wang S, Rubens J, Allen S, Orr B, Eberhart C, Raabe E. Abstract 5182: Targeting abnormal metabolism downstream of MYC in atypical teratoid/rhabdoid tumors Cancer Research. 77: 5182-5182. DOI: 10.1158/1538-7445.Am2017-5182 |
0.484 |
|
| 2017 |
Guo H, Akhtarkhavari S, Eberhart CG, Kaur H, Raabe EH. Abstract 3868: The stem cell factor LIN28B regulates proliferation and apoptosis in diffuse intrinsic pontine glioma Cancer Research. 77: 3868-3868. DOI: 10.1158/1538-7445.Am2017-3868 |
0.492 |
|
| 2017 |
Kaur H, Ali SZ, Guo H, Akhtarkhavari S, Rodriguez F, Eberhart CG, Raabe EH. Abstract 3865: Targeting the epigenetic modifier HMGA2 in lethal adult and pediatric gliomas inhibits invasion, growth and tumorigenicity Cancer Research. 77: 3865-3865. DOI: 10.1158/1538-7445.Am2017-3865 |
0.508 |
|
| 2017 |
Hanaford AR, Poore B, Eberhart CG, Raabe EH. Abstract 3560: 6-diazo-5-oxo-norleucine resistant MYC-driven medulloblastoma tumors are sensitive to inhibition of glutaminase suggesting a possible glutaminase-independent mechanism of resistance Cancer Research. 77: 3560-3560. DOI: 10.1158/1538-7445.Am2017-3560 |
0.338 |
|
| 2017 |
Poore BA, Taylor I, Rubens J, Hanaford A, Maxwell M, Eberhart C, Raabe E. Abstract 3549: C-MYC sensitizes GBM with primitive features to glutamine metabolism disruption Cancer Research. 77: 3549-3549. DOI: 10.1158/1538-7445.Am2017-3549 |
0.458 |
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| 2017 |
Brosnan-Cashman JA, Rizzo AJ, Goger E, Myers KM, Zarinshenas R, Davis C, Yuan M, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract 3466: ALT-positive pediatric high grade glioma cells display chemosensitivity to ATR pathway inhibition Cancer Research. 77: 3466-3466. DOI: 10.1158/1538-7445.Am2017-3466 |
0.43 |
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| 2017 |
Brosnan-Cashman JA, Yuan M, Rizzo AJ, Myers KM, Barry WT, Davis C, Esopi DM, Rakheja D, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Abstract 3465: Context-dependent effects of ATRX loss on telomere biology in glioma cells Cancer Research. 77: 3465-3465. DOI: 10.1158/1538-7445.Am2017-3465 |
0.415 |
|
| 2017 |
Arnold A, Rodriguez F, Eberhart C, Raabe E. LGG-13. SYNERGISTIC TREATMENT FOR PEDIATRIC LOW GRADE GLIOMA WITH THE DUAL MTORC1/2 INHIBITOR TAK-228 AND MEK INHIBITOR TRAMETINIB Neuro-Oncology. 19: iv35-iv36. DOI: 10.1093/Neuonc/Nox083.146 |
0.48 |
|
| 2017 |
Rubens J, Wang S, Price A, Allen S, Orr B, Eberhart C, Raabe E. ATRT-08. TARGETING GLUTAMINE METABOLISM IN MYC DRIVEN ATYPICAL TERATOID RHABDOID TUMORS Neuro-Oncology. 19: iv2-iv3. DOI: 10.1093/Neuonc/Nox083.007 |
0.392 |
|
| 2016 |
Kaur H, Ali SZ, Huey L, Hütt-Cabezas M, Taylor I, Mao XG, Weingart M, Chu Q, Rodriguez FJ, Eberhart CG, Raabe EH. The transcriptional modulator HMGA2 promotes stemness and tumorigenicity in glioblastoma. Cancer Letters. PMID 27102002 DOI: 10.1016/J.Canlet.2016.04.020 |
0.444 |
|
| 2016 |
Hanaford AR, Archer TC, Price A, Kahlert UD, Maciaczyk J, Nikkhah G, Kim JW, Ehrenberger T, Clemons PA, Dančík V, Seashore-Ludlow B, Viswanathan V, Stewart ML, Rees M, Shamji AF, ... ... Raabe EH, et al. DiSCoVERing innovative therapies for rare tumors: combining genetically accurate disease models with in silico analysis to identify novel therapeutic targets. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27012813 DOI: 10.1158/1078-0432.Ccr-15-3011 |
0.365 |
|
| 2016 |
Ahsan S, Haffner M, Eberhart C, Raabe E. Abstract 4440: Diffuse intrinsic pontine glioma epigenetic marks change depending on cell culture conditions: Implications for investigating epigenetically directed therapy Cancer Research. 76: 4440-4440. DOI: 10.1158/1538-7445.Am2016-4440 |
0.46 |
|
| 2016 |
Hanaford AR, Archer TC, Price A, Kahlert U, Maciaczyk J, Guido N, Kim W, Ehrenberger T, Clemons P, Dancik V, Seashore-Ludlow B, Viswanathan V, Stewart M, Rees M, Shamji A, ... ... Raabe EH, et al. Abstract 2476: DiSCoVERing innovative therapies for rare tumors: Combining genetically accurate disease models with advanced in silico analysis to identify novel therapeutic targets Cancer Research. 76: 2476-2476. DOI: 10.1158/1538-7445.Am2016-2476 |
0.375 |
|
| 2016 |
Kaur H, Hütt-Cabezas M, Taylor I, Weingart M, Rodriguez F, Eberhart CG, Raabe EH. Abstract 2464: Disrupting the epigenetic modifier HMGA2 in DIPG and GBM inhibits tumor invasion, growth and tumorigenicity Cancer Research. 76: 2464-2464. DOI: 10.1158/1538-7445.Am2016-2464 |
0.42 |
|
| 2016 |
Rubens J, Price A, Orr B, Eberhart C, Raabe E. Abstract 2102: Targeting mTOR downstream of LIN28 in atypical teratoid rhabdoid tumors promotes apoptosis and suppresses tumorigenicity Cancer Research. 76: 2102-2102. DOI: 10.1158/1538-7445.Am2016-2102 |
0.45 |
|
| 2016 |
Kaur H, Hütt-Cabezas M, Taylor I, Weingart M, Rodriguez F, Eberhart C, Raabe E. PDTB-11. DISRUPTING THE EPIGENETIC MODIFIER HMGA2 IN LETHAL PEDIATRIC AND ADULT GLIOMAS INHIBITS INVASION, GROWTH AND TUMORIGENICITY Neuro-Oncology. 18: vi152-vi152. DOI: 10.1093/Neuonc/Now212.631 |
0.337 |
|
| 2016 |
Ahsan S, Haffner M, Miyahara H, Natsumeda M, Liu Y, Rocco L, Eberhart C, Raabe E. HG-69CELL CULTURE CONDITIONS AFFECT DIFFUSE INTRINSIC PONTINE GLIOMA EPIGENETICS AND RESPONSE TO THERAPEUTIC AGENTS Neuro-Oncology. 18: iii64.1-iii64. DOI: 10.1093/Neuonc/Now073.65 |
0.319 |
|
| 2016 |
Rubens J, Price A, Eberhart C, Raabe E. AT-14mTOR INHIBITION BLOCKS A KEY LIN28 DOWNSTREAM TARGET AND ENHANCES CISPLATIN MEDIATED CYTOTOXICITY LEADING TO EXTENDED SURVIVAL IN ATYPICAL TERATOID RHABDOID TUMORS Neuro-Oncology. 18: iii4.2-iii4. DOI: 10.1093/Neuonc/Now065.13 |
0.429 |
|
| 2015 |
Kahlert UD, Cheng M, Koch K, Marchionni L, Fan X, Raabe EH, Maciaczyk J, Glunde K, Eberhart CG. Alterations in Cellular Metabolome after Pharmacological Inhibition of Notch in Glioblastoma Cells. International Journal of Cancer. Journal International Du Cancer. PMID 26422827 DOI: 10.1002/Ijc.29873 |
0.448 |
|
| 2015 |
Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, ... ... Raabe EH, et al. Erratum: Functionally defined therapeutic targets in diffuse intrinsic pontine glioma. Nature Medicine. 21: 827. PMID 26151328 DOI: 10.1038/Nm0715-827A |
0.308 |
|
| 2015 |
Taylor IC, Hütt-Cabezas M, Brandt WD, Kambhampati M, Nazarian J, Chang HT, Warren KE, Eberhart CG, Raabe EH. Disrupting NOTCH Slows Diffuse Intrinsic Pontine Glioma Growth, Enhances Radiation Sensitivity, and Shows Combinatorial Efficacy With Bromodomain Inhibition. Journal of Neuropathology and Experimental Neurology. PMID 26115193 DOI: 10.1097/Nen.0000000000000216 |
0.467 |
|
| 2015 |
Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, ... ... Raabe EH, et al. Functionally defined therapeutic targets in diffuse intrinsic pontine glioma. Nature Medicine. 21: 555-9. PMID 25939062 DOI: 10.1038/Nm.3855 |
0.359 |
|
| 2015 |
Weingart MF, Roth JJ, Hutt-Cabezas M, Busse TM, Kaur H, Price A, Maynard R, Rubens J, Taylor I, Mao XG, Xu J, Kuwahara Y, Allen SJ, Erdreich-Epstein A, Weissman BE, ... ... Raabe EH, et al. Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target. Oncotarget. 6: 3165-77. PMID 25638158 DOI: 10.18632/Oncotarget.3078 |
0.517 |
|
| 2015 |
Kaur H, Hütt-Cabezas M, Weingart MF, Xu J, Kuwahara Y, Erdreich-Epstein A, Weissman BE, Eberhart CG, Raabe EH. The chromatin-modifying protein HMGA2 promotes atypical teratoid/rhabdoid cell tumorigenicity. Journal of Neuropathology and Experimental Neurology. 74: 177-85. PMID 25575139 DOI: 10.1097/Nen.0000000000000161 |
0.494 |
|
| 2015 |
Brandt WD, Schreck KC, Bar EE, Taylor I, Marchionni L, Raabe E, Eberhart CG, Rodriguez FJ. Notch signaling activation in pediatric low-grade astrocytoma. Journal of Neuropathology and Experimental Neurology. 74: 121-31. PMID 25575134 DOI: 10.1097/Nen.0000000000000155 |
0.424 |
|
| 2015 |
Hanaford A, Guerra C, Eberhart C, Raabe E, Price A. Abstract 504: Glutamine metabolic inhibitors suppress growth and tumorigenicity in MYC and MYCN-driven pediatric malignancies Cancer Research. 75: 504-504. DOI: 10.1158/1538-7445.Am2015-504 |
0.394 |
|
| 2015 |
Taylor I, Ahsan S, Price A, Eberhart C, Raabe EH. Abstract 494: MYC, dominant negative p53 and AKT transform human neural stem cells into primitive neuro-ectodermal tumors sensitive to glutaminase inhibitors Cancer Research. 75: 494-494. DOI: 10.1158/1538-7445.Am2015-494 |
0.465 |
|
| 2015 |
Kaur H, Hütt-Cabezas M, Taylor I, Asnaghi L, Rodriguez F, Orr BA, Eberhart CG, Raabe EH. Abstract 4222: Targeting HMGA2 suppresses GBM stemness, invasion and tumorigenicity Cancer Research. 75: 4222-4222. DOI: 10.1158/1538-7445.Am2015-4222 |
0.504 |
|
| 2015 |
Rubens J, Weingart M, Price A, Hutt-Cabezas M, Taylor I, Allen S, Orr B, Eberhart C, Raabe E. Abstract 3272: Targeting LIN28 and the RAS/MAP kinase pathway in atypical teratoid rhabdoid tumors Cancer Research. 75: 3272-3272. DOI: 10.1158/1538-7445.Am2015-3272 |
0.494 |
|
| 2015 |
Yuan M, An P, Lim KS, Taylor I, Rodriguez F, Raabe E, Eberhart C. MTR-03ATRX REDUCTION PROMOTES ALKYLATING AGENT RESISTANCE AND XENOGRAFT GROWTH IN A SUBSET OF GLIOMAS Neuro-Oncology. 17: v124.3-v124. DOI: 10.1093/Neuonc/Nov219.03 |
0.429 |
|
| 2015 |
Brandt WD, Schreck KC, Bar EE, Taylor I, Marchionni L, Raabe E, Eberhart CG, Rodriguez FJ. Lg-04Notch Signaling Activation In Pediatric Low-Grade Astrocytoma. Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov061.73 |
0.422 |
|
| 2015 |
Rubens J, Price A, Eberhart C, Raabe E. AT-05 * TARGETING mTOR DOWNSTREAM OF LIN28 IN ATYPICAL TERATOID RHABDOID TUMORS PROMOTES APOPTOSIS AND SUPPRESSES TUMORIGENICITY Neuro-Oncology. 17: iii2-iii2. DOI: 10.1093/Neuonc/Nov061.5 |
0.452 |
|
| 2015 |
Taylor I, Ahsan S, Weingart M, Eberhart C, Raabe E. HG-12 * LIN28 AND MYC EXPRESSING PEDIATRIC GLIOBLASTOMAS ARE SENSITIVE TO INHIBITORS OF GLUTAMINE METABOLISM Neuro-Oncology. 17: iii13-iii13. DOI: 10.1093/Neuonc/Nov061.49 |
0.461 |
|
| 2015 |
Kaur H, Hutt-Cabezas M, Taylor I, Weingart M, Rodriguez F, Eberhart C, Raabe E. HG-08 * DISRUPTING THE EPIGENETIC MODIFIER HMGA2 IN DIPG AND GBM INHIBITS TUMOR INVASION, GROWTH AND TUMORIGENICITY Neuro-Oncology. 17: iii12-iii12. DOI: 10.1093/Neuonc/Nov061.45 |
0.531 |
|
| 2015 |
Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily M, Quist MJ, Davis L, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung T, Sun W, Kogiso M, ... ... Raabe E, et al. BT-02 * FUNCTIONALLY-DEFINED THERAPEUTIC TARGETS IN DIFFUSE INTRINSIC PONTINE GLIOMA Neuro-Oncology. 17: iii3-iii3. DOI: 10.1093/Neuonc/Nov061.12 |
0.381 |
|
| 2015 |
Saratsis A, Kambhampati M, Hall J, Stampar M, Xi G, Raabe E, Packer R, Nazarian J. Bt-01Tenascin-C: A Novel Therapeutic Target In Pediatric Brainstem Glioma Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov061.11 |
0.446 |
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| 2015 |
Hanaford A, Archer T, Tamayo P, Pomeroy S, Eberhart C, Raabe E. MB-27 * PATHWAY ANALYSIS OF A HUMAN NEURAL STEM CELL MODEL OF AGGRESSIVE MEDULLOBLASTOMA REVEALS CKD INBHIBITION AS A POTENTIAL THERAPEUTIC MODALITY Neuro-Oncology. 17: iii25-iii26. DOI: 10.1093/Neuonc/Nov061.103 |
0.506 |
|
| 2014 |
Kahlert UD, Suwala AK, Raabe EH, Siebzehnrubl FA, Suarez MJ, Orr BA, Bar EE, Maciaczyk J, Eberhart CG. ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres. Brain Pathology (Zurich, Switzerland). PMID 25521330 DOI: 10.1111/Bpa.12240 |
0.47 |
|
| 2014 |
Martin AM, Raabe E, Eberhart C, Cohen KJ. Management of pediatric and adult patients with medulloblastoma. Current Treatment Options in Oncology. 15: 581-94. PMID 25194927 DOI: 10.1007/S11864-014-0306-4 |
0.378 |
|
| 2014 |
Rodriguez FJ, Raabe EH. mTOR: a new therapeutic target for pediatric low-grade glioma? Cns Oncology. 3: 89-91. PMID 25055011 DOI: 10.2217/Cns.14.4 |
0.431 |
|
| 2014 |
Ahsan S, Raabe EH, Haffner MC, Vaghasia A, Warren KE, Quezado M, Ballester LY, Nazarian J, Eberhart CG, Rodriguez FJ. Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma. Acta Neuropathologica Communications. 2: 59. PMID 24894482 DOI: 10.1186/2051-5960-2-59 |
0.396 |
|
| 2014 |
Saratsis AM, Kambhampati M, Snyder K, Yadavilli S, Devaney JM, Harmon B, Hall J, Raabe EH, An P, Weingart M, Rood BR, Magge SN, MacDonald TJ, Packer RJ, Nazarian J. Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes. Acta Neuropathologica. 127: 881-95. PMID 24297113 DOI: 10.1007/S00401-013-1218-2 |
0.412 |
|
| 2014 |
Ahsan S, Raabe E, Haffner MC, Nazarian J, Warren K, Ballester L, Quezado M, Eberhart C, Rodriguez FJ. Abstract 384: Epigenetic derangements in histone and cytosine methylation are unique to diffuse intrinsic pontine glioma (DIPG) Cancer Research. 74: 384-384. DOI: 10.1158/1538-7445.Am2014-384 |
0.4 |
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| 2014 |
Taylor IC, Hutt-Cabezas M, Weingart M, Warren K, Chang H, Nazarian J, Eberhart CG, Raabe EH. Abstract 3099: Dual targeting of mTOR and Notch disrupts growth and promotes apoptosis in diffuse intrinsic pontine glioma Cancer Research. 74: 3099-3099. DOI: 10.1158/1538-7445.Am2014-3099 |
0.477 |
|
| 2014 |
Hanaford AR, Eberhart CG, Raabe EH. Abstract 3090: Targeting glutamine metabolism as a therapeutic strategy in MYC-driven medulloblastoma Cancer Research. 74: 3090-3090. DOI: 10.1158/1538-7445.Am2014-3090 |
0.431 |
|
| 2014 |
Kaur H, Hütt M, Mao X, Orr BA, Eberhart CG, Raabe EH. Abstract 3031: HMGA2 promotes invasion and stemness in glioblastoma Cancer Research. 74: 3031-3031. DOI: 10.1158/1538-7445.Am2014-3031 |
0.48 |
|
| 2014 |
Stampar M, Yadavilli S, Brown KJ, Raabe EH, Warren KE, Kambhampati M, Packer RJ, Nazarian J. Pm-20Comparative Proteome Profiling Of In Vivo And In Vitro Models Of Dipg Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou268.20 |
0.397 |
|
| 2014 |
Eberhart C, Raabe E, Hanaford A, Pomeroy S. MODELLING HIGH MYC MEDULLOBLASTOMA AND OTHER BRAIN TUMORS USING HUMAN NEURAL STEM CELLS Neuro-Oncology. 16: iii4-iii4. DOI: 10.1093/Neuonc/Nou206.12 |
0.478 |
|
| 2014 |
Classen CF, William D, Linnebacher M, Farhod A, Kedr W, Elsabe B, Fadel S, Van Gool S, De Vleeschouwer S, Koks C, Garg A, Ehrhardt M, Riva M, De Vleeschouwer S, Agostinis P, ... ... Raabe E, ... ... Raabe E, ... ... Raabe E, ... ... Raabe E, et al. HIGH GRADE GLIOMAS AND DIPG Neuro-Oncology. 16: i40-i59. DOI: 10.1093/Neuonc/Nou071 |
0.307 |
|
| 2013 |
Hütt-Cabezas M, Karajannis MA, Zagzag D, Shah S, Horkayne-Szakaly I, Rushing EJ, Cameron JD, Jain D, Eberhart CG, Raabe EH, Rodriguez FJ. Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target. Neuro-Oncology. 15: 1604-14. PMID 24203892 DOI: 10.1093/Neuonc/Not132 |
0.428 |
|
| 2013 |
Ballester LY, Wang Z, Shandilya S, Miettinen M, Burger PC, Eberhart CG, Rodriguez FJ, Raabe E, Nazarian J, Warren K, Quezado MM. Morphologic characteristics and immunohistochemical profile of diffuse intrinsic pontine gliomas. The American Journal of Surgical Pathology. 37: 1357-64. PMID 24076776 DOI: 10.1097/Pas.0B013E318294E817 |
0.468 |
|
| 2013 |
Heaphy CM, Schreck KC, Raabe E, Mao XG, An P, Chu Q, Poh W, Jiao Y, Rodriguez FJ, Odia Y, Meeker AK, Eberhart CG. A glioblastoma neurosphere line with alternative lengthening of telomeres. Acta Neuropathologica. 126: 607-8. PMID 24022427 DOI: 10.1007/S00401-013-1174-X |
0.406 |
|
| 2013 |
Raabe E, Kieran MW, Cohen KJ. New strategies in pediatric gliomas: molecular advances in pediatric low-grade gliomas as a model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4553-8. PMID 23881924 DOI: 10.1158/1078-0432.Ccr-13-0662 |
0.431 |
|
| 2013 |
Mao XG, Hütt-Cabezas M, Orr BA, Weingart M, Taylor I, Rajan AK, Odia Y, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG, Raabe EH. LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Oncotarget. 4: 1050-64. PMID 23846349 DOI: 10.18632/Oncotarget.1131 |
0.508 |
|
| 2013 |
Saratsis A, Yadavilli S, Kambhampati M, Raabe E, Magge S, Nazarian J. Abstract C30: Four dimensional molecular analysis of pediatric diffuse intrinsic pontine glioma Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C30 |
0.422 |
|
| 2013 |
Ahsan SF, Hanaford A, Weingart M, Taylor I, Eberhart C, Raabe E. Abstract 5051: MYC-driven models of primitive neuroectodermal tumor are sensitive to inhibitors of glutamine metabolism. Cancer Research. 73: 5051-5051. DOI: 10.1158/1538-7445.Am2013-5051 |
0.514 |
|
| 2013 |
Hutt M, Goldstein W, Nazarian J, Price A, Lim KJ, Warren K, Chang H, Eberhart C, Raabe E. Abstract 5049: Targeting the Notch and mTOR pathways in diffuse intrinsic pontine glioma. Cancer Research. 73: 5049-5049. DOI: 10.1158/1538-7445.Am2013-5049 |
0.484 |
|
| 2013 |
Shah S, Hutt M, Karajannis MA, Raabe E, Eberhart CG, Rodriguez FJ. Abstract 5048: mTORC1/mTORC2 signaling in pediatric low grade glioma and pilocytic astrocytoma. Cancer Research. 73: 5048-5048. DOI: 10.1158/1538-7445.Am2013-5048 |
0.44 |
|
| 2013 |
Taylor I, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart C, Raabe EH. Abstract 5044: MYC drives formation of primative neuro-ectodermal tumors in human neural stem cells derived from multiple brain regions. Cancer Research. 73: 5044-5044. DOI: 10.1158/1538-7445.Am2013-5044 |
0.454 |
|
| 2013 |
Kaur H, Hutt M, Mao X, Eberhart CG, Raabe EH. Abstract 3742: Targeting the stem cell factor HMGA2 to improve outcomes in glioblastoma. Cancer Research. 73: 3742-3742. DOI: 10.1158/1538-7445.Am2013-3742 |
0.482 |
|
| 2013 |
Ding D, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart C, Raabe E. Abstract 2607: BMI1 and dominant negative p53 cooperate to suppress AKT-mediated oncogene-induced senescence and promote transformation in human neural stem cells. Cancer Research. 73: 2607-2607. DOI: 10.1158/1538-7445.Am2013-2607 |
0.465 |
|
| 2013 |
Hanaford AR, Eberhart CG, Raabe EH. Abstract 1872: Targeting MYC-driven medulloblastoma using inhibitors of glutamine metabolism. Cancer Research. 73: 1872-1872. DOI: 10.1158/1538-7445.Am2013-1872 |
0.465 |
|
| 2012 |
Raabe EH, Eberhart CG. Methylome alterations "mark" new therapeutic opportunities in glioblastoma. Cancer Cell. 22: 417-8. PMID 23079650 DOI: 10.1016/J.Ccr.2012.10.001 |
0.362 |
|
| 2012 |
Hutt M, Lim KJ, Warren K, Chang HT, Eberhart CG, Raabe EH. Abstract 2480: High-level activation of the Notch pathway in diffuse intrinsic pontine glioma Cancer Research. 72: 2480-2480. DOI: 10.1158/1538-7445.Am2012-2480 |
0.518 |
|
| 2011 |
Raabe EH, Lim KS, Kim JM, Meeker A, Mao XG, Nikkhah G, Maciaczyk J, Kahlert U, Jain D, Bar E, Cohen KJ, Eberhart CG. BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3590-9. PMID 21636552 DOI: 10.1158/1078-0432.Ccr-10-3349 |
0.473 |
|
| 2011 |
Raabe EH, Keefer JR, Mitchell SE, Hong K, DiFazio M, Strouse JJ. Subtotal splenic embolization is a safe and effective treatment for isolated splenic vascular tumors associated with consumptive coagulopathy. Journal of Pediatric Hematology/Oncology. 33: 383-6. PMID 21606851 DOI: 10.1097/Mph.0B013E3182172515 |
0.351 |
|
| 2011 |
Lim KS, Bar EE, Raabe EH, Jain D, Eberhart CG. Abstract 3459: Expression of oncogene-induced senescence markers in pilocytic astrocytomaIs associated with younger age and longer survival Cancer Research. 71: 3459-3459. DOI: 10.1158/1538-7445.Am2011-3459 |
0.435 |
|
| 2011 |
Mao X, Raabe EH, Maciaczyk J, Kahlert U, Nikkhah G, Eberhart CG. Abstract 3454: LIN28 is expressed in glioblastomas and promotes KRAS-mediated transformation of human neural stem cells Cancer Research. 71: 3454-3454. DOI: 10.1158/1538-7445.Am2011-3454 |
0.43 |
|
| 2011 |
Raabe EH, Lim KS, Mao X, Bar E, Meeker A, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG. Abstract 3303: BRAF activation induces cellular transformation and senescence and down-regulates SOX2 in human neural stem cells: a model of pilocytic astrocytoma Cancer Research. 71: 3303-3303. DOI: 10.1158/1538-7445.Am2011-3303 |
0.439 |
|
| 2010 |
Raabe EH, Eberhart CG. High-risk medulloblastoma: does c-myc amplification overrule histopathology? Pediatric Blood & Cancer. 54: 344-5. PMID 20063409 DOI: 10.1002/Pbc.22398 |
0.387 |
|
| 2010 |
Raabe EH, Maciaczyk J, Kahlert U, Nikkhah G, Eberhart C. Abstract 4352: Using human neural stem cells to model pediatric high grade gliomas: The role of p53, c-myc, and EGFRvIII in neoplastic transformation Cancer Research. 70: 4352-4352. DOI: 10.1158/1538-7445.Am10-4352 |
0.453 |
|
| 2008 |
Winter C, Pawel B, Seiser E, Zhao H, Raabe E, Wang Q, Judkins AR, Attiyeh E, Maris JM. Neural cell adhesion molecule (NCAM) isoform expression is associated with neuroblastoma differentiation status. Pediatric Blood & Cancer. 51: 10-6. PMID 18213713 DOI: 10.1002/Pbc.21475 |
0.42 |
|
| 2007 |
Raabe EH, Laudenslager M, Winter C, Wasserman N, Cole K, LaQuaglia M, Maris DJ, Mosse YP, Maris JM. Prevalence and functional consequence of PHOX2B mutations in neuroblastoma. Oncogene. 27: 469-76. PMID 17637745 DOI: 10.1038/Sj.Onc.1210659 |
0.389 |
|
| 2004 |
Sun LQ, Lee DW, Zhang Q, Xiao W, Raabe EH, Meeker A, Miao D, Huso DL, Arceci RJ. Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG. Genes & Development. 18: 1035-46. PMID 15105378 DOI: 10.1101/Gad.1176104 |
0.492 |
|
| 2001 |
Raabe EH, Abdurrahman L, Behbehani G, Arceci RJ. An SNF2 factor involved in mammalian development and cellular proliferation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 221: 92-105. PMID 11357197 DOI: 10.1002/Dvdy.1128 |
0.537 |
|
| 2000 |
Lee DW, Zhang K, Ning ZQ, Raabe EH, Tintner S, Wieland R, Wilkins BJ, Kim JM, Blough RI, Arceci RJ. Proliferation-associated SNF2-like gene (PASG): a SNF2 family member altered in leukemia. Cancer Research. 60: 3612-22. PMID 10910076 |
0.452 |
|
| 1998 |
Kim J, Lee DW, Ning ZQ, Zhang K, Blough R, Raabe E, Arceci R. #653 Chromosomal mapping of a new helicase gene Journal of Pediatric Hematology/Oncology. 20: 392. DOI: 10.1097/00043426-199807000-00091 |
0.401 |
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