Herman Wolosker, M.D., Ph.D. - Publications

Affiliations: 
Technion - Israel Institute of Technology, Haifa, Haifa District, Israel 
Website:
http://wolosker.net.technion.ac.il/

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Folorunso OO, Brown SE, Baruah J, Harvey TL, Jami SA, Radzishevsky I, Wolosker H, McNally JM, Gray JA, Vasudevan A, Balu DT. D-serine availability modulates prefrontal cortex inhibitory interneuron development and circuit maturation. Scientific Reports. 13: 9595. PMID 37311798 DOI: 10.1038/s41598-023-35615-5  0.382
2022 Tapanes SA, Arizanovska D, Díaz MM, Folorunso OO, Harvey T, Brown SE, Radzishevsky I, Close LN, Jagid JR, Graciolli Cordeiro J, Wolosker H, Balu DT, Liebl DJ. Inhibition of glial D-serine release rescues synaptic damage after brain injury. Glia. PMID 35195906 DOI: 10.1002/glia.24161  0.401
2021 Wolosker H, Radzishevsky I. Promiscuous enzymes generating d-amino acids in mammals: Why they may still surprise us? The Biochemical Journal. 478: 1175-1178. PMID 33710333 DOI: 10.1042/BCJ20200988  0.451
2020 Ploux E, Bouet V, Radzishevsky I, Wolosker H, Freret T, Billard JM. Serine Racemase Deletion Affects the Excitatory/Inhibitory Balance of the Hippocampal CA1 Network. International Journal of Molecular Sciences. 21. PMID 33322577 DOI: 10.3390/ijms21249447  0.323
2020 Bodner O, Radzishevsky I, Foltyn VN, Touitou A, Valenta A, Rangel IF, Panizzutti R, Kennedy RT, Billard JM, Wolosker H. D-Serine signaling and NMDAR-mediated synaptic plasticity are regulated by system A-type of glutamine/D-serine dual transporters. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32661027 DOI: 10.1523/Jneurosci.0801-20.2020  0.753
2020 Wolosker H, Balu DT. D-Serine as the gatekeeper of NMDA receptor activity: implications for the pharmacologic management of anxiety disorders. Translational Psychiatry. 10: 184. PMID 32518273 DOI: 10.1038/S41398-020-00870-X  0.464
2020 Coyle JT, Balu D, Wolosker H. D-Serine, the Shape-Shifting NMDA Receptor Co-agonist. Neurochemical Research. PMID 32189130 DOI: 10.1007/S11064-020-03014-1  0.522
2019 Neame S, Safory H, Radzishevsky I, Touitou A, Marchesani F, Marchetti M, Kellner S, Berlin S, Foltyn VN, Engelender S, Billard JM, Wolosker H. The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle. Proceedings of the National Academy of Sciences of the United States of America. 116: 20736-20742. PMID 31548413 DOI: 10.1073/Pnas.1909458116  0.553
2019 Gaisler-Salomon I, Lander SS, Chakraborty D, Asraf K, Safory H, Wolosker H, Kaphzan H. 21.3 NEURONAL-ASTROCYTIC REGULATION OF GLUTAMATE HOMEOSTASIS: RELEVANCE TO COGNITIVE DYSFUNCTION IN SCHIZOPHRENIA Schizophrenia Bulletin. 45: S124-S124. DOI: 10.1093/Schbul/Sbz022.087  0.303
2018 Kaplan E, Zubedat S, Radzishevsky I, Valenta AC, Rechnitz O, Sason H, Sajrawi C, Bodner O, Konno K, Esaki K, Derdikman D, Yoshikawa T, Watanabe M, Kennedy RT, Billard JM, ... ... Wolosker H, et al. ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d-serine and neurodevelopment. Proceedings of the National Academy of Sciences of the United States of America. PMID 30185558 DOI: 10.1073/Pnas.1722677115  0.533
2018 Mesuret G, Khabbazzadeh S, Bischoff AM, Safory H, Wolosker H, Hülsmann S. A neuronal role of the Alanine-Serine-Cysteine-1 transporter (SLC7A10, Asc-1) for glycine inhibitory transmission and respiratory pattern. Scientific Reports. 8: 8536. PMID 29867218 DOI: 10.1038/S41598-018-26868-6  0.402
2018 Wolosker H. The Neurobiology of d-Serine Signaling. Advances in Pharmacology (San Diego, Calif.). 82: 325-348. PMID 29413526 DOI: 10.1016/Bs.Apha.2017.08.010  0.543
2017 Balu DT, Presti KT, Huang CCY, Muszynski K, Radzishevsky I, Wolosker H, Guffanti G, Ressler KJ, Coyle JT. Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning. Biological Psychiatry. PMID 29025687 DOI: 10.1016/J.Biopsych.2017.08.012  0.488
2017 Wolosker H, Balu DT, Coyle JT. Astroglial Versus Neuronal D-Serine: Check Your Controls! Trends in Neurosciences. PMID 28756007 DOI: 10.1016/J.Tins.2017.06.010  0.472
2016 Wolosker H, Balu DT, Coyle JT. The Rise and Fall of the d-Serine-Mediated Gliotransmission Hypothesis. Trends in Neurosciences. PMID 27742076 DOI: 10.1016/J.Tins.2016.09.007  0.522
2016 Kolodney G, Dumin E, Safory H, Rosenberg D, Mori H, Radzishevsky I, Wolosker H. Nuclear compartmentalization of serine racemase regulates d-serine production. IMPLICATIONS FOR N-METHYL-d-ASPARTATE (NMDA) RECEPTOR ACTIVATION. The Journal of Biological Chemistry. 291: 2630. PMID 26851299 DOI: 10.1074/jbc.A115.699496  0.41
2016 Sason H, Billard JM, Smith GP, Safory H, Neame S, Kaplan E, Rosenberg D, Zubedat S, Foltyn VN, Christoffersen CT, Bundgaard C, Thomsen C, Avital A, Christensen KV, Wolosker H. Asc-1 Transporter Regulation of Synaptic Activity via the Tonic Release of d-Serine in the Forebrain. Cerebral Cortex (New York, N.Y. : 1991). PMID 26796213 DOI: 10.1093/Cercor/Bhv350  0.497
2015 Kolodney G, Dumin E, Safory H, Rosenberg D, Mori H, Radzishevisky I, Wolosker H. Nuclear Compartmentalization of Serine Racemase Regulates D-serine Production: Implications for N-methyl-D-aspartate (NMDA) Receptor Activation. The Journal of Biological Chemistry. PMID 26553873 DOI: 10.1074/Jbc.M115.699496  0.558
2015 Safory H, Neame S, Shulman Y, Zubedat S, Radzishevsky I, Rosenberg D, Sason H, Engelender S, Avital A, Hülsmann S, Schiller J, Wolosker H. The alanine-serine-cysteine-1 (Asc-1) transporter controls glycine levels in the brain and is required for glycinergic inhibitory transmission. Embo Reports. 16: 590-8. PMID 25755256 DOI: 10.15252/Embr.201439561  0.348
2015 Le Bail M, Martineau M, Sacchi S, Yatsenko N, Radzishevsky I, Conrod S, Ait Ouares K, Wolosker H, Pollegioni L, Billard JM, Mothet JP. Identity of the NMDA receptor coagonist is synapse specific and developmentally regulated in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 112: E204-13. PMID 25550512 DOI: 10.1073/Pnas.1416668112  0.723
2014 Dikopoltsev E, Foltyn VN, Zehl M, Jensen ON, Mori H, Radzishevsky I, Wolosker H. FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine. The Journal of Biological Chemistry. 289: 33904-15. PMID 25336657 DOI: 10.1074/Jbc.M114.618405  0.543
2014 Ma TM, Paul BD, Fu C, Hu S, Zhu H, Blackshaw S, Wolosker H, Snyder SH. Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk. The Journal of Biological Chemistry. 289: 29631-41. PMID 25164819 DOI: 10.1074/Jbc.M114.571604  0.788
2014 Labarrière M, Thomas F, Dutar P, Pollegioni L, Wolosker H, Billard JM. Circuit-specific changes in D-serine-dependent activation of the N-methyl-D-aspartate receptor in the aging hippocampus. Age (Dordrecht, Netherlands). 36: 9698. PMID 25138794 DOI: 10.1007/S11357-014-9698-0  0.461
2013 Wolosker H, Radzishevsky I. The serine shuttle between glia and neurons: implications for neurotransmission and neurodegeneration. Biochemical Society Transactions. 41: 1546-50. PMID 24256252 DOI: 10.1042/Bst20130220  0.498
2013 Ehmsen JT, Ma TM, Sason H, Rosenberg D, Ogo T, Furuya S, Snyder SH, Wolosker H. D-serine in glia and neurons derives from 3-phosphoglycerate dehydrogenase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12464-9. PMID 23884950 DOI: 10.1523/Jneurosci.4914-12.2013  0.691
2013 Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto S, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, ... ... Wolosker H, et al. Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss. Proceedings of the National Academy of Sciences of the United States of America. 110: E2518-27. PMID 23776240 DOI: 10.1073/Pnas.1306832110  0.376
2013 Rosenberg D, Artoul S, Segal AC, Kolodney G, Radzishevsky I, Dikopoltsev E, Foltyn VN, Inoue R, Mori H, Billard JM, Wolosker H. Neuronal D-serine and glycine release via the Asc-1 transporter regulates NMDA receptor-dependent synaptic activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3533-44. PMID 23426681 DOI: 10.1523/Jneurosci.3836-12.2013  0.527
2013 Radzishevsky I, Sason H, Wolosker H. D-serine: physiology and pathology. Current Opinion in Clinical Nutrition and Metabolic Care. 16: 72-5. PMID 23041616 DOI: 10.1097/Mco.0B013E32835A3466  0.524
2012 Wolosker H, Mori H. Serine racemase: an unconventional enzyme for an unconventional transmitter. Amino Acids. 43: 1895-904. PMID 22847782 DOI: 10.1007/S00726-012-1370-3  0.559
2012 Radzishevsky I, Wolosker H. An enzymatic-HPLC assay to monitor endogenous D-serine release from neuronal cultures. Methods in Molecular Biology (Clifton, N.J.). 794: 291-7. PMID 21956571 DOI: 10.1007/978-1-61779-331-8_19  0.516
2011 Wolosker H. Serine racemase and the serine shuttle between neurons and astrocytes. Biochimica Et Biophysica Acta. 1814: 1558-66. PMID 21224019 DOI: 10.1016/J.Bbapap.2011.01.001  0.535
2010 Foltyn VN, Zehl M, Dikopoltsev E, Jensen ON, Wolosker H. Phosphorylation of mouse serine racemase regulates D-serine synthesis. Febs Letters. 584: 2937-41. PMID 20493854 DOI: 10.1016/J.Febslet.2010.05.022  0.433
2010 Rosenberg D, Kartvelishvily E, Shleper M, Klinker CM, Bowser MT, Wolosker H. Neuronal release of D-serine: a physiological pathway controlling extracellular D-serine concentration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2951-61. PMID 20371631 DOI: 10.1096/Fj.09-147967  0.504
2009 Balan L, Foltyn VN, Zehl M, Dumin E, Dikopoltsev E, Knoh D, Ohno Y, Kihara A, Jensen ON, Radzishevsky IS, Wolosker H. Feedback inactivation of D-serine synthesis by NMDA receptor-elicited translocation of serine racemase to the membrane. Proceedings of the National Academy of Sciences of the United States of America. 106: 7589-94. PMID 19380732 DOI: 10.1073/Pnas.0809442106  0.432
2009 Heresco-Levy U, Vass A, Bloch B, Wolosker H, Dumin E, Balan L, Deutsch L, Kremer I. Pilot controlled trial of D-serine for the treatment of post-traumatic stress disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 1275-82. PMID 19366490 DOI: 10.1017/S1461145709000339  0.345
2008 Wolosker H, Dumin E, Balan L, Foltyn VN. D-amino acids in the brain: D-serine in neurotransmission and neurodegeneration. The Febs Journal. 275: 3514-26. PMID 18564180 DOI: 10.1111/J.1742-4658.2008.06515.X  0.578
2008 Madeira C, Freitas ME, Vargas-Lopes C, Wolosker H, Panizzutti R. Increased brain D-amino acid oxidase (DAAO) activity in schizophrenia. Schizophrenia Research. 101: 76-83. PMID 18378121 DOI: 10.1016/J.Schres.2008.02.002  0.736
2007 Wolosker H. NMDA receptor regulation by D-serine: new findings and perspectives. Molecular Neurobiology. 36: 152-64. PMID 17952659 DOI: 10.1007/S12035-007-0038-6  0.538
2007 Gustafson EC, Stevens ER, Wolosker H, Miller RF. Endogenous D-serine contributes to NMDA-receptor-mediated light-evoked responses in the vertebrate retina. Journal of Neurophysiology. 98: 122-30. PMID 17507508 DOI: 10.1152/Jn.00057.2006  0.505
2007 Bendikov I, Nadri C, Amar S, Panizzutti R, De Miranda J, Wolosker H, Agam G. A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia. Schizophrenia Research. 90: 41-51. PMID 17156977 DOI: 10.1016/J.Schres.2006.10.010  0.737
2007 Dumin E, Wolosker H. Neurobiology of D-amino acids Handbook of Neurochemistry and Molecular Neurobiology: Amino Acids and Peptides in the Nervous System. 207-224. DOI: 10.1007/978-0-387-30373-4_9  0.333
2006 Wolosker H. D-serine regulation of NMDA receptor activity. Science's Stke : Signal Transduction Knowledge Environment. 2006: pe41. PMID 17033043 DOI: 10.1126/Stke.3562006Pe41  0.582
2006 Dumin E, Bendikov I, Foltyn VN, Misumi Y, Ikehara Y, Kartvelishvily E, Wolosker H. Modulation of D-serine levels via ubiquitin-dependent proteasomal degradation of serine racemase. The Journal of Biological Chemistry. 281: 20291-302. PMID 16714286 DOI: 10.1074/Jbc.M601971200  0.553
2006 Kartvelishvily E, Shleper M, Balan L, Dumin E, Wolosker H. Neuron-derived D-serine release provides a novel means to activate N-methyl-D-aspartate receptors. The Journal of Biological Chemistry. 281: 14151-62. PMID 16551623 DOI: 10.1074/Jbc.M512927200  0.558
2006 Amar S, Bendikov I, Nadri C, Panizzutti R, De Miranda J, Wolosker H, Agam G. Decreased D-serine levels in CSF of schizophrenia patients European Neuropsychopharmacology. 16: S10. DOI: 10.1016/S0924-977X(06)80013-1  0.675
2005 Shleper M, Kartvelishvily E, Wolosker H. D-serine is the dominant endogenous coagonist for NMDA receptor neurotoxicity in organotypic hippocampal slices. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9413-7. PMID 16221850 DOI: 10.1523/Jneurosci.3190-05.2005  0.561
2005 Foltyn VN, Bendikov I, De Miranda J, Panizzutti R, Dumin E, Shleper M, Li P, Toney MD, Kartvelishvily E, Wolosker H. Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity. The Journal of Biological Chemistry. 280: 1754-63. PMID 15536068 DOI: 10.1074/Jbc.M405726200  0.716
2002 De Miranda J, Panizzutti R, Foltyn VN, Wolosker H. Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine. Proceedings of the National Academy of Sciences of the United States of America. 99: 14542-7. PMID 12393813 DOI: 10.1073/Pnas.222421299  0.761
2002 Wolosker H, Panizzutti R, De Miranda J. Neurobiology through the looking-glass: D-serine as a new glial-derived transmitter. Neurochemistry International. 41: 327-32. PMID 12176074 DOI: 10.1016/S0197-0186(02)00055-4  0.775
2002 Ribeiro CS, Reis M, Panizzutti R, de Miranda J, Wolosker H. Glial transport of the neuromodulator D-serine. Brain Research. 929: 202-9. PMID 11864625 DOI: 10.1016/S0006-8993(01)03390-X  0.766
2002 Wang H, Wolosker H, Morris JF, Pevsner J, Snyder SH, Selkoe DJ. Naturally occurring free D-aspartate is a nuclear component of cells in the mammalian hypothalamo-neurohypophyseal system. Neuroscience. 109: 1-4. PMID 11784695 DOI: 10.1016/S0306-4522(01)00545-0  0.583
2001 Panizzutti R, De Miranda J, Ribeiro CS, Engelender S, Wolosker H. A new strategy to decrease N-methyl-D-aspartate (NMDA) receptor coactivation: inhibition of D-serine synthesis by converting serine racemase into an eliminase. Proceedings of the National Academy of Sciences of the United States of America. 98: 5294-9. PMID 11309496 DOI: 10.1073/Pnas.091002298  0.744
2000 Takahashi M, Doré S, Ferris CD, Tomita T, Sawa A, Wolosker H, Borchelt DR, Iwatsubo T, Kim SH, Thinakaran G, Sisodia SS, Snyder SH. Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease. Neuron. 28: 461-73. PMID 11144356 DOI: 10.1016/S0896-6273(00)00125-2  0.67
2000 Wang H, Wolosker H, Pevsner J, Snyder SH, Selkoe DJ. Regulation of rat magnocellular neurosecretory system by D-aspartate: evidence for biological role(s) of a naturally occurring free D-amino acid in mammals. The Journal of Endocrinology. 167: 247-52. PMID 11054638 DOI: 10.1677/Joe.0.1670247  0.579
2000 De Miranda J, Santoro A, Engelender S, Wolosker H. Human serine racemase: moleular cloning, genomic organization and functional analysis. Gene. 256: 183-8. PMID 11054547 DOI: 10.1016/S0378-1119(00)00356-5  0.502
2000 Wolosker H, D'Aniello A, Snyder SH. D-aspartate disposition in neuronal and endocrine tissues: ontogeny, biosynthesis and release. Neuroscience. 100: 183-9. PMID 10996468 DOI: 10.1016/S0306-4522(00)00321-3  0.609
2000 Reis M, Farage M, Wolosker H. Chloride-dependent inhibition of vesicular glutamate uptake by alpha-keto acids accumulated in maple syrup urine disease. Biochimica Et Biophysica Acta. 1475: 114-8. PMID 10832024 DOI: 10.1016/S0304-4165(00)00069-6  0.337
2000 Barañano DE, Wolosker H, Bae BI, Barrow RK, Snyder SH, Ferris CD. A mammalian iron ATPase induced by iron. The Journal of Biological Chemistry. 275: 15166-73. PMID 10809751 DOI: 10.1074/Jbc.275.20.15166  0.696
2000 Mothet JP, Parent AT, Wolosker H, Brady RO, Linden DJ, Ferris CD, Rogawski MA, Snyder SH. D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 4926-31. PMID 10781100 DOI: 10.1073/Pnas.97.9.4926  0.798
1999 Ferris CD, Jaffrey SR, Sawa A, Takahashi M, Brady SD, Barrow RK, Tysoe SA, Wolosker H, Barañano DE, Doré S, Poss KD, Snyder SH. Haem oxygenase-1 prevents cell death by regulating cellular iron. Nature Cell Biology. 1: 152-7. PMID 10559901 DOI: 10.1038/11072  0.707
1999 Wolosker H, Blackshaw S, Snyder SH. Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 96: 13409-14. PMID 10557334 DOI: 10.1073/Pnas.96.23.13409  0.736
1999 Wolosker H, Sheth KN, Takahashi M, Mothet JP, Brady RO, Ferris CD, Snyder SH. Purification of serine racemase: biosynthesis of the neuromodulator D-serine. Proceedings of the National Academy of Sciences of the United States of America. 96: 721-5. PMID 9892700 DOI: 10.1073/Pnas.96.2.721  0.803
1998 Lai MM, Burnett PE, Wolosker H, Blackshaw S, Snyder SH. Cain, a novel physiologic protein inhibitor of calcineurin. The Journal of Biological Chemistry. 273: 18325-31. PMID 9660798 DOI: 10.1074/Jbc.273.29.18325  0.75
1998 Wolosker H, Kline D, Bian Y, Blackshaw S, Cameron AM, Fralich TJ, Schnaar RL, Snyder SH. Molecularly cloned mammalian glucosamine-6-phosphate deaminase localizes to transporting epithelium and lacks oscillin activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 91-9. PMID 9438414 DOI: 10.1096/Fasebj.12.1.91  0.59
1997 Wolosker H, Rocha JB, Engelender S, Panizzutti R, De Miranda J, de Meis L. Sarco/endoplasmic reticulum Ca2+-ATPase isoforms: diverse responses to acidosis. The Biochemical Journal. 321: 545-50. PMID 9020893 DOI: 10.1042/Bj3210545  0.629
1996 Wolosker H, Reis M, Assreuy J, de Meis L. Inhibition of glutamate uptake and proton pumping in synaptic vesicles by S-nitrosylation. Journal of Neurochemistry. 66: 1943-8. PMID 8780021 DOI: 10.1046/J.1471-4159.1996.66051943.X  0.347
1996 Wolosker H, Panizzutti R, Engelender S. Inhibition of creatine kinase by S-nitrosoglutathione. Febs Letters. 392: 274-6. PMID 8774860 DOI: 10.1016/0014-5793(96)00829-0  0.653
1996 Wolosker H, de Souza DO, de Meis L. Regulation of glutamate transport into synaptic vesicles by chloride and proton gradient. The Journal of Biological Chemistry. 271: 11726-31. PMID 8662610 DOI: 10.1074/Jbc.271.20.11726  0.362
1990 Wolosker H, Petretski JH, De Meis L. Modification of ATP regulatory function in sarcoplasmic reticulum Ca2(+)-ATPase by hydrophobic molecules. European Journal of Biochemistry / Febs. 193: 873-7. PMID 2147416 DOI: 10.1111/J.1432-1033.1990.Tb19411.X  0.316
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