Stephen J. McConoughey, Ph.D.

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
neurodegeneration
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"Stephen McConoughey"
Mean distance: 17.91 (cluster 11)
 
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Rajiv Ratan grad student 2008 Weill Cornell Medical College
 (The role of transglutaminase 2 as a selective transcriptional corepressor.)
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Publications

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Wolford CC, McConoughey SJ, Jalgaonkar SP, et al. (2013) Transcription factor ATF3 links host adaptive response to breast cancer metastasis. The Journal of Clinical Investigation. 123: 2893-906
Wolford CC, McConoughey S, Yin X, et al. (2011) Abstract 2843: Tumor macrophages utilize ATF3 to promote breast cancer metastasis Cancer Research. 71: 2843-2843
Yin X, Wolford CC, Chang YS, et al. (2010) ATF3, an adaptive-response gene, enhances TGF{beta} signaling and cancer-initiating cell features in breast cancer cells. Journal of Cell Science. 123: 3558-65
McConoughey SJ, Basso M, Niatsetskaya ZV, et al. (2010) Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease. Embo Molecular Medicine. 2: 349-70
Niatsetskaya Z, Basso M, Speer RE, et al. (2010) HIF prolyl hydroxylase inhibitors prevent neuronal death induced by mitochondrial toxins: therapeutic implications for Huntington's disease and Alzheimer's disease. Antioxidants & Redox Signaling. 12: 435-43
McConoughey SJ, Niatsetskaya ZV, Pasternack R, et al. (2009) A nonradioactive dot blot assay for transglutaminase activity. Analytical Biochemistry. 390: 91-3
Ratan RR, Siddiq A, Aminova L, et al. (2008) Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury. Annals of the New York Academy of Sciences. 1147: 383-94
Ratan RR, Siddiq A, Smirnova N, et al. (2007) Harnessing hypoxic adaptation to prevent, treat, and repair stroke. Journal of Molecular Medicine (Berlin, Germany). 85: 1331-8
Krasnikov BF, Kim SY, McConoughey SJ, et al. (2005) Transglutaminase activity is present in highly purified nonsynaptosomal mouse brain and liver mitochondria. Biochemistry. 44: 7830-43
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