Paul E. Brennan, Ph.D.
Affiliations: | University of Oxford, Oxford, United Kingdom |
Area:
Bio-Organic and Synthetic ChemistryGoogle:
"Paul Brennan"Mean distance: 7.93
Parents
Sign in to add mentor| Paul Allan Bartlett | grad student | 2000 | UC Berkeley | |
| (I. Phosphinate inhibitors of peptidoglycan biosynthesis. II. Development of a new ring system for combinatorial chemistry.) | ||||
| Steven Victor Ley | post-doc | Cambridge | ||
Children
Sign in to add trainee| Milan Mrázek Fowkes | research assistant | 2015-2016 | Oxford |
| Matthew T O Holland | grad student | 2020- | |
| David Bowkett | grad student | 2012-2016 | Oxford |
| Oakley Cox | grad student | 2012-2016 | Oxford |
| Moses Moustakim | grad student | 2015-2018 | Oxford |
| Miranda Wright | grad student | 2015-2018 | Oxford |
| Milan Mrázek Fowkes | grad student | 2018-2021 | Oxford |
| Mark G McLaughlin | post-doc | ||
| Joshua Almond-Thynne | post-doc | 2017-2018 | Oxford |
BETA: Related publications
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Publications
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| Balıkçı E, Marques AMC, Bauer LG, et al. (2024) Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist. Journal of Medicinal Chemistry |
| O'Brien DP, Jones HB, Guenther F, et al. (2023) Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides. Molecular & Cellular Proteomics : McP. 100609 |
| Fowkes MM, Troeberg L, Brennan PE, et al. (2023) Development of Selective ADAMTS-5 Peptide Substrates to Monitor Proteinase Activity. Journal of Medicinal Chemistry. 66: 3522-3539 |
| Frank N, Nugent J, Shire BR, et al. (2022) Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane. Nature |
| Fowkes MM, Das Neves Borges P, Cacho-Nerin F, et al. (2022) Imaging articular cartilage in osteoarthritis using targeted peptide radiocontrast agents. Plos One. 17: e0268223 |
| De Cesco S, Davis JB, Brennan PE. (2020) TargetDB: A target information aggregation tool and tractability predictor. Plos One. 15: e0232644 |
| Cottone L, Cribbs AP, Khandelwal G, et al. (2020) Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death. Cancer Research |
| Kahn Tareque R, Hassell-Hart S, Krojer T, et al. (2020) Deliberately Losing Control of C-H Activation Processes in the Design of Small Molecule Fragment Arrays Targeting Peroxisomal Metabolism. Chemmedchem |
| Ni X, Heidenreich D, Christott T, et al. (2019) Structural Insights into Interaction Mechanisms of Alternative Piperazine-urea YEATS Domain Binders in MLLT1. Acs Medicinal Chemistry Letters. 10: 1661-1666 |
| Fagan V, Johansson C, Gileadi C, et al. (2019) A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. Journal of Medicinal Chemistry |