Scott B. Ficarro, Ph.D.

Affiliations: 
2002 University of Virginia, Charlottesville, VA 
Area:
Analytical Biochemistry
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"Scott Ficarro"
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Donald F. Hunt grad student 2002 UVA
 (Enrichment and analysis of phosphorylated peptides by immobilized metal affinity chromatography and nanoflow -HPLC /microelectrospray ionization /tandem mass spectrometry.)
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Publications

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Siriwongsup S, Schmoker AM, Ficarro SB, et al. (2024) Bioorthogonally activated reactive species for target identification. Chem. 10: 1306-1315
Wachter F, Nowak RP, Ficarro S, et al. (2024) Structural characterization of methylation-independent PP2A assembly guides Alphafold2Multimer prediction of family-wide PP2A complexes. The Journal of Biological Chemistry. 107268
Li Z, Lu W, Beyett TS, et al. (2024) ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases. Journal of Medicinal Chemistry
Zhu D, Wang Z, Zhao JJ, et al. (2024) Author Correction: The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells. Nature Medicine
Chen H, Lye MF, Gorgulla C, et al. (2023) A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex. Plos Pathogens. 19: e1011781
Cruite JT, Nowak RP, Donovan KA, et al. (2023) Covalent Stapling of the Cereblon Sensor Loop Histidine Using Sulfur-Heterocycle Exchange. Acs Medicinal Chemistry Letters. 14: 1576-1581
Nowak RP, Ragosta L, Huerta F, et al. (2023) Development of a covalent cereblon-based PROTAC employing a fluorosulfate warhead. Rsc Chemical Biology. 4: 906-912
Casirati G, Cosentino A, Mucci A, et al. (2023) Epitope editing enables targeted immunotherapy of acute myeloid leukaemia. Nature
Lu W, Fan M, Ji W, et al. (2023) Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors. Journal of Medicinal Chemistry
Lu W, Liu Y, Gao Y, et al. (2023) Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of Medicinal Chemistry. 66: 3356-3371
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