Alexander Buffone, Ph.D.

2012 Chemical and Biological Engineering State University of New York, Buffalo, Buffalo, NY, United States 
Biomedical Engineering, Chemical Engineering
"Alexander Buffone"


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Sriram Neelamegham grad student 2012 SUNY Buffalo
 (Identification of the terminal glycosyltransferases critical in mediating selectin-dependent adhesion in human leukocytes.)
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Dougher CWL, Buffone A, Nemeth MJ, et al. (2017) The blood-borne sialyltransferase ST6Gal-1 is a negative systemic regulator of granulopoiesis. Journal of Leukocyte Biology
Buffone A, Nasirikenari M, Manhardt CT, et al. (2016) Leukocyte-borne α(1,3)-fucose is a negative regulator of β2-integrin-dependent recruitment in lung inflammation. Journal of Leukocyte Biology
Stolfa G, Mondal N, Zhu Y, et al. (2016) Using CRISPR-Cas9 to quantify the contributions of O-glycans, N-glycans and Glycosphingolipids to human leukocyte-endothelium adhesion. Scientific Reports. 6: 30392
Mondal N, Stolfa G, Antonopoulos A, et al. (2016) Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin-Dependent Rolling in the Multistep Leukocyte Adhesion Cascade. Arteriosclerosis, Thrombosis, and Vascular Biology
Mondal N, Buffone A, Stolfa G, et al. (2015) ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes. Blood. 125: 687-96
Mondal N, Buffone A, Neelamegham S. (2013) Distinct glycosyltransferases synthesize E-selectin ligands in human vs. mouse leukocytes. Cell Adhesion & Migration. 7: 288-92
Buffone A, Mondal N, Gupta R, et al. (2013) Silencing α1,3-fucosyltransferases in human leukocytes reveals a role for FUT9 enzyme during E-selectin-mediated cell adhesion. The Journal of Biological Chemistry. 288: 1620-33
Marathe DD, Buffone A, Chandrasekaran EV, et al. (2010) Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins. Blood. 115: 1303-12
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