Brendan P. Flynn, Ph.D.

Affiliations: 
2012 Mechanical and Industrial Engineering Northeastern University, Boston, MA, United States 
Area:
Biomedical Engineering, Mechanical Engineering, Human Development
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"Brendan Flynn"

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Jeffrey W. Ruberti grad student 2012 Northeastern University
 (Experimental and Theoretical Investigations on the Mechanical Stabilization and Enzymatic Degradation of Collagen.)
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Publications

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Flynn BP, DSouza AV, Kanick SC, et al. (2013) White light-informed optical properties improve ultrasound-guided fluorescence tomography of photoactive protoporphyrin IX. Journal of Biomedical Optics. 18: 046008
Flynn BP, Tilburey GE, Ruberti JW. (2013) Highly sensitive single-fibril erosion assay demonstrates mechanochemical switch in native collagen fibrils. Biomechanics and Modeling in Mechanobiology. 12: 291-300
Chang SW, Flynn BP, Ruberti JW, et al. (2012) Molecular mechanism of force induced stabilization of collagen against enzymatic breakdown. Biomaterials. 33: 3852-9
Camp RJ, Liles M, Beale J, et al. (2011) Molecular mechanochemistry: low force switch slows enzymatic cleavage of human type I collagen monomer. Journal of the American Chemical Society. 133: 4073-8
Flynn BP, Bhole AP, Saeidi N, et al. (2010) Mechanical strain stabilizes reconstituted collagen fibrils against enzymatic degradation by mammalian collagenase matrix metalloproteinase 8 (MMP-8). Plos One. 5: e12337
Zareian R, Church KP, Saeidi N, et al. (2010) Probing collagen/enzyme mechanochemistry in native tissue with dynamic, enzyme-induced creep. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 9917-26
Bhole AP, Flynn BP, Liles M, et al. (2009) Mechanical strain enhances survivability of collagen micronetworks in the presence of collagenase: implications for load-bearing matrix growth and stability. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 367: 3339-62
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