Nouri Neamati

Affiliations: 
Pharmacy University of Michigan, Ann Arbor, Ann Arbor, MI 
 2000- Pharmaceutical Sciences University of Southern California, Los Angeles, CA, United States 
Area:
Pharmacology, Biochemistry
Website:
https://pharmacy.umich.edu/people/neamati
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"Nouri Neamati"
Bio:

Neamati, Nouri, Design, synthesis and cellular and molecular pharmacology of 2'-bromo-4'-epidaunorubicin (WP401): A novel non-cross-resistant anthracycline antibiotic with the intrinsic ability to circumvent P-glycoprotein-mediated drug resistance (1995). Texas Medical Center Dissertations (via ProQuest). AAI9532532.
http://digitalcommons.library.tmc.edu/dissertations/AAI9532532

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Parents

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Waldemar Priebe grad student 1995 The University of Texas Graduate School of Biomedical Sciences at Houston
 (Design, synthesis and cellular and molecular pharmacology of 2'-bromo-4'-epidaunorubicin (WP401): A novel non-cross-resistant anthracycline antibiotic with the intrinsic ability to circumvent P-glycoprotein-mediated drug resistance.)

Children

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Laith Q. Al-Mawsawi grad student 2007 USC
Zahrah Zawahir grad student 2009 USC
Tino W. Sanchez grad student 2012 USC
Helen N. Ha grad student 2013 USC
Melissa Millard grad student 2013 USC
Divya Pathania grad student 2013 USC
Erik Serrao grad student 2013 USC
Yumna H. Shabaik grad student 2013 USC
Shili Xu grad student 2013 USC
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Publications

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Chaudhuri D, Lu T, Jacob B, et al. (2023) Lipidation of a bioactive cyclotide-based CXCR4 antagonist greatly improves its pharmacokinetic profile in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 359: 26-32
Yao J, Yin Y, Han H, et al. (2022) Pyrazolone derivatives as potent and selective small-molecule SIRT5 inhibitors. European Journal of Medicinal Chemistry. 247: 115024
Liu Y, Debnath B, Kumar S, et al. (2022) Identification of 2-hydroxybenzoic acid derivatives as selective SIRT5 inhibitors. European Journal of Medicinal Chemistry. 241: 114623
Xue D, Xu Y, Kyani A, et al. (2022) Discovery and Lead Optimization of Benzene-1,4-disulfonamides as Oxidative Phosphorylation Inhibitors. Journal of Medicinal Chemistry. 65: 343-368
Huddle BC, Grimley E, Chtcherbinine M, et al. (2020) Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. European Journal of Medicinal Chemistry. 211: 113060
Shergalis A, Xue D, Gharbia FZ, et al. (2020) Characterization of aminobenzylphenols as protein disulfide isomerase inhibitors in glioblastoma cell lines. Journal of Medicinal Chemistry
Sanna V, Youssef MF, Pala N, et al. (2020) Inhibition of Human Immunodeficiency Virus-1 Integrase by β-Diketo Acid Coated Gold Nanoparticles. Acs Medicinal Chemistry Letters. 11: 857-861
Hughes MM, Hooftman A, Angiari S, et al. (2019) Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation. Cell Reports. 29: 151-161.e5
Xu S, Liu Y, Yang K, et al. (2019) Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes. Theranostics. 9: 2282-2298
Machiraju PK, Yedla P, Gubbala SP, et al. (2019) Identification, synthesis and evaluation of CSF1R inhibitors using fragment based drug design. Computational Biology and Chemistry. 80: 374-383
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