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Gary F. Merrill

Affiliations: 
Oregon State University, Corvallis, OR 
Area:
Genetics, Molecular Biology, Medical Biophysics
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"Gary Merrill"
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Children

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Ahmet Koc grad student 2003 Oregon State
Jason R. Merwin grad student 2004 Oregon State

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Publications

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Breysse DH, Boone RM, Long CM, et al. (2020) Carbonyl reductase 1 plays a significant role in converting doxorubicin to cardiotoxic doxorubicinol in mouse liver, but the majority of the doxorubicinol-forming activity remains unidentified. Drug Metabolism and Disposition: the Biological Fate of Chemicals
Shearn CT, Fennimore B, Orlicky DJ, et al. (2019) Cholestatic liver disease results increased production of reactive aldehydes and an atypical periportal hepatic antioxidant response. Free Radical Biology & Medicine
Schaupp CM, White CC, Merrill GF, et al. (2015) Metabolism of doxorubicin to the cardiotoxic metabolite doxorubicinol is increased in a mouse model of chronic glutathione deficiency: A potential role for carbonyl reductase 3. Chemico-Biological Interactions. 234: 154-61
Hyter S, Coleman DJ, Ganguli-Indra G, et al. (2013) Endothelin-1 is a transcriptional target of p53 in epidermal keratinocytes and regulates ultraviolet-induced melanocyte homeostasis. Pigment Cell & Melanoma Research. 26: 247-58
Merrill GF, Long CM, Gomez LA, et al. (2012) The Txnrd1 Gene Encoding Cytosolic Thioredoxin Reductase Is Required for Efficient P53 Target Gene Induction in Liver of Irradiated Mice Free Radical Biology and Medicine. 53: S47
Rollins MF, van der Heide DM, Weisend CM, et al. (2010) Hepatocytes lacking thioredoxin reductase 1 have normal replicative potential during development and regeneration. Journal of Cell Science. 123: 2402-12
Stoner CS, Pearson GD, Koç A, et al. (2009) Effect of thioredoxin deletion and p53 cysteine replacement on human p53 activity in wild-type and thioredoxin reductase null yeast. Biochemistry. 48: 9156-69
Suvorova ES, Lucas O, Weisend CM, et al. (2009) Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes. Plos One. 4: e6158
Bondareva AA, Capecchi MR, Iverson SV, et al. (2007) Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome. Free Radical Biology & Medicine. 43: 911-23
Koc A, Merrill GF. (2007) Checkpoint deficient rad53-11 yeast cannot accumulate dNTPs in response to DNA damage. Biochemical and Biophysical Research Communications. 353: 527-30
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