Robert L. Bevins, Ph.D.

Affiliations: 
2005 University of Kentucky, Lexington, KY 
Area:
Toxicology
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"Robert Bevins"

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Stephen Zimmer grad student 2005 University of Kentucky
 (Potentiation of camptothecin cytotoxicity by the sequential addition of histone deacetylase inhibitors.)
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Publications

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Song L, Bevins R, Anderson BD. (2006) Kinetics and mechanisms of activation of alpha-amino acid ester prodrugs of camptothecins. Journal of Medicinal Chemistry. 49: 4344-55
Tangirala RS, Antony S, Agama K, et al. (2006) Synthesis and biological assays of E-ring analogs of camptothecin and homocamptothecin. Bioorganic & Medicinal Chemistry. 14: 6202-12
Bevins RL, Zimmer SG. (2005) It's about time: scheduling alters effect of histone deacetylase inhibitors on camptothecin-treated cells. Cancer Research. 65: 6957-66
Du W, Curran DP, Bevins RL, et al. (2002) Synthesis and evaluation of a novel E-ring modified alpha-hydroxy keto ether analogue of camptothecin. Bioorganic & Medicinal Chemistry. 10: 103-10
Bom D, Curran DP, Zhang J, et al. (2001) The highly lipophilic DNA topoisomerase I inhibitor DB-67 displays elevated lactone levels in human blood and potent anticancer activity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 74: 325-33
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