Irena Levitan

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biomedical Engineering, Cell Biology
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"Irena Levitan"
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Publications

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Fancher IS, Levitan I. (2023) Membrane Cholesterol Interactions with Proteins in Hypercholesterolemia-Induced Endothelial Dysfunction. Current Atherosclerosis Reports. 25: 535-541
Barbera N, Granados ST, Vanoye CG, et al. (2022) Cholesterol-induced suppression of Kir2 channels is mediated by decoupling at the inter-subunit interfaces. Iscience. 25: 104329
Rezende L, Couto NFD, Fernandes-Braga W, et al. (2022) OxLDL induces membrane structure rearrangement leading to biomechanics alteration and migration deficiency in macrophage. Biochimica Et Biophysica Acta. Biomembranes. 1864: 183951
Levitan I. (2021) Evaluating membrane structure by Laurdan imaging: Disruption of lipid packing by oxidized lipids. Current Topics in Membranes. 88: 235-256
Ahn SJ, Fancher IS, Granados ST, et al. (2021) Cholesterol-Induced Suppression of Endothelial Kir Channels Is a Driver of Impairment of Arteriolar Flow-Induced Vasodilation in Humans. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12117
Ayee MAA, Levitan I. (2021) Lipoprotein-Induced Increases in Cholesterol and 7-Ketocholesterol Result in Opposite Molecular-Scale Biophysical Effects on Membrane Structure. Frontiers in Cardiovascular Medicine. 8: 715932
Srivastava N, Tauseef M, Amin R, et al. (2020) Noncanonical function of long myosin light chain kinase in increasing ER-PM junctions and augmentation of SOCE. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Fancher IS, Le Master E, Ahn SJ, et al. (2020) Impairment of Flow-Sensitive Inwardly Rectifying K Channels via Disruption of Glycocalyx Mediates Obesity-Induced Endothelial Dysfunction. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314935
Fancher IS, Levitan I. (2020) Endothelial inwardly-rectifying K+ channels as a key component of shear stress-induced mechanotransduction Current Topics in Membranes. 85: 59-88
Bogachkov YY, Chen L, Le Master E, et al. (2020) LDL induces cholesterol loading, inhibits endothelial proliferation, and angiogenesis in Matrigels: Correlation with impaired angiogenesis during wound healing. American Journal of Physiology. Cell Physiology
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