Basil S. Perdicakis, Ph.D.

Affiliations: 
2004 University of Waterloo, Waterloo, ON, Canada 
Area:
Chemical Engineering
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"Basil Perdicakis"

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E J. Jervis grad student 2004 University of Waterloo
 (Photo-control of iNOS inhibition in RAW 264.7 cell culture by near infrared multiphoton photolysis of a caged iNOS selective inhibitor (Bhc -1400W).)
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Publications

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Perdicakis B, Montgomery HJ, Guillemette JG, et al. (2005) Analysis of slow-binding enzyme inhibitors at elevated enzyme concentrations. Analytical Biochemistry. 337: 211-23
Perdicakis B, Montgomery HJ, Abbott GL, et al. (2005) Photocontrol of nitric oxide production in cell culture using a caged isoform selective inhibitor. Bioorganic & Medicinal Chemistry. 13: 47-57
Perdicakis B, Montgomery HJ, Guillemette JG, et al. (2004) Validation and characterization of uninhibited enzyme kinetics performed in multiwell plates. Analytical Biochemistry. 332: 122-36
Montgomery HJ, Bartlett R, Perdicakis B, et al. (2003) Activation of constitutive nitric oxide synthases by oxidized calmodulin mutants. Biochemistry. 42: 7759-68
Fishlock D, Perdicakis B, Montgomery HJ, et al. (2003) Synthesis and evaluation of trans 3,4-cyclopropyl L-arginine analogues as isoform selective inhibitors of nitric oxide synthase. Bioorganic & Medicinal Chemistry. 11: 869-73
Montgomery HJ, Perdicakis B, Fishlock D, et al. (2002) Photo-control of nitric oxide synthase activity using a caged isoform specific inhibitor. Bioorganic & Medicinal Chemistry. 10: 1919-27
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