Joseph Edgar Darling

Affiliations: 
2010-2015 Chemistry Syracuse University, Syracuse, NY, United States 
 2015-2019 National Institutes of Health, Bethesda, MD 
 2019-2021 Frederick National Laboratory 
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"Joseph Darling"
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Publications

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McGovern-Gooch KR, Rodrigues T, Darling JE, et al. (2016) Ghrelin octanoylation is completely stabilized in biological samples by alkyl fluorophosphonates. Endocrinology. en20161657
Wellman MK, Patterson ZR, MacKay H, et al. (2015) Novel Regulator of Acylated Ghrelin, CF801, Reduces Weight Gain, Rebound Feeding after a Fast, and Adiposity in Mice. Frontiers in Endocrinology. 6: 144
McGovern KR, Darling JE, Hougland JL. (2015) Progress in Small Molecule and Biologic Therapeutics Targeting Ghrelin Signaling. Mini Reviews in Medicinal Chemistry
Zhao F, Darling JE, Gibbs RA, et al. (2015) A new class of ghrelin O-acyltransferase inhibitors incorporating triazole-linked lipid mimetic groups. Bioorganic & Medicinal Chemistry Letters. 25: 2800-3
Darling JE, Zhao F, Loftus RJ, et al. (2015) Structure-activity analysis of human ghrelin O-acyltransferase reveals chemical determinants of ghrelin selectivity and acyl group recognition. Biochemistry. 54: 1100-10
Darling JE, Prybolsky EP, Sieburg M, et al. (2013) A fluorescent peptide substrate facilitates investigation of ghrelin recognition and acylation by ghrelin O-acyltransferase. Analytical Biochemistry. 437: 68-76
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