Eric F. Johnson, Ph.D.
Affiliations: | Department of Molecular Medicine | Scripps Research Institute, La Jolla, La Jolla, CA, United States | |
| 1972 | Chemistry | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Website:
https://www.scripps.edu/research/faculty/ejohnsonGoogle:
"Eric F. Johnson" OR "Eric Foster Johnson"Bio:
https://archive.org/details/facultypublicati19711974univ/page/n245
http://vivo.scripps.edu/individual/n13860
DOI: 10.1021/ja00786a007
Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Russell Stephen Drago | grad student | 1972 | UIUC | |
| (Time Correlation Function Analysis of Raman Lineshapes.) | ||||
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Publications
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| Mastracchio A, Lai C, Torrent M, et al. (2019) Investigation of biaryl heterocycles as inhibitors of Wee1 kinase. Bioorganic & Medicinal Chemistry Letters |
| Hsu MH, Johnson EF. (2019) Active site differences between substrate-free and ritonavir-bound cytochrome P450 (CYP) 3A5 reveal plasticity differences between CYP3A5 and CYP3A4. The Journal of Biological Chemistry |
| Jennings GK, Hsu MH, Shock LS, et al. (2018) Non-covalent interactions dominate dynamic heme distortion in cytochrome P450 4B1. The Journal of Biological Chemistry |
| Hsu MH, Savas U, Johnson EF. (2017) The X-ray Crystal Structure of the Human Monooxygenase Cytochrome P450 3A5-Ritonavir Complex Reveals Active Site Differences between P450s 3A4 and 3A5. Molecular Pharmacology |
| Liu R, Lyu X, Hsu MH, et al. (2017) Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes. Angewandte Chemie (International Ed. in English) |
| Albertolle ME, Kim D, Nagy LD, et al. (2017) Heme-thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition. The Journal of Biological Chemistry |
| Hsu MH, Baer BR, Rettie AE, et al. (2017) The Crystal Structure of Cytochrome P450 4B1 (CYP4B1) Monoxygenase Complexed with Octane Discloses Several Structural Adaptations for ω-Hydroxylation. The Journal of Biological Chemistry |
| Butler CR, Ogilvie K, Martinez-Alsina L, et al. (2016) Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality. Journal of Medicinal Chemistry |
| Savas U, Wei S, Hsu MH, et al. (2016) 20-Hydroxyeicosatetraenoic Acid (HETE) Dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: Normalization of Blood Pressure by Sodium Restriction, Hydrochlorothiazide, or Blockade of the Type 1 Angiotensin II Receptor. The Journal of Biological Chemistry |
| Brodney MA, Beck EM, Butler CR, et al. (2015) Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors. Journal of Medicinal Chemistry. 58: 3223-52 |