| Year |
Citation |
Score |
| 2010 |
Bargonetti J, Champeil E, Tomasz M. Differential toxicity of DNA adducts of mitomycin C. Journal of Nucleic Acids. 2010. PMID 20798760 DOI: 10.4061/2010/698960 |
0.527 |
|
| 2010 |
Weng MW, Zheng Y, Jasti VP, Champeil E, Tomasz M, Wang Y, Basu AK, Tang MS. Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model. Nucleic Acids Research. 38: 6976-84. PMID 20647419 DOI: 10.1093/Nar/Gkq576 |
0.503 |
|
| 2010 |
Boamah EK, Brekman A, Tomasz M, Myeku N, Figueiredo-Pereira M, Hunter S, Meyer J, Bhosle RC, Bargonetti J. DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1. Chemical Research in Toxicology. 23: 1151-62. PMID 20536192 DOI: 10.1021/Tx900420K |
0.443 |
|
| 2010 |
Weng MW, Zheng Y, Jasti VP, Champeil E, Tomasz M, Wang Ys, Basu AK, Tang MS. Abstract 1967: UvrABC excision of interstrand crosslink mitomycin C-DNA lesion induces double-stranded DNA breaks Cancer Research. 70: 1967-1967. DOI: 10.1158/1538-7445.Am10-1967 |
0.526 |
|
| 2009 |
Shen X, Do H, Li Y, Chung WH, Tomasz M, de Winter JP, Xia B, Elledge SJ, Wang W, Li L. Recruitment of Fanconi Anemia and Breast Cancer Proteins to DNA Damage Sites Is Differentially Governed by Replication Molecular Cell. 35: 716-723. PMID 19748364 DOI: 10.1016/J.Molcel.2009.06.034 |
0.419 |
|
| 2008 |
Paz MM, Ladwa S, Champeil E, Liu Y, Rockwell S, Boamah EK, Bargonetti J, Callahan J, Roach J, Tomasz M. Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry. Chemical Research in Toxicology. 21: 2370-8. PMID 19053323 DOI: 10.1021/Tx8002615 |
0.484 |
|
| 2008 |
Champeil E, Paz MM, Ladwa S, Clement CC, Zatorski A, Tomasz M. Synthesis of an oligodeoxyribonucleotide adduct of mitomycin C by the postoligomerization method via a triamino mitosene. Journal of the American Chemical Society. 130: 9556-65. PMID 18588303 DOI: 10.1021/Ja802118P |
0.454 |
|
| 2007 |
Boamah EK, White DE, Talbott KE, Arva NC, Berman D, Tomasz M, Bargonetti J. Mitomycin-DNA adducts induce p53-dependent and p53-independent cell death pathways. Acs Chemical Biology. 2: 399-407. PMID 17530733 DOI: 10.1021/Cb700060T |
0.384 |
|
| 2005 |
Utzat CD, Clement CC, Ramos LA, Das A, Tomasz M, Basu AK. DNA adduct of the mitomycin C metabolite 2,7-diaminomitosene is a nontoxic and nonmutagenic DNA lesion in vitro and in vivo. Chemical Research in Toxicology. 18: 213-23. PMID 15720125 DOI: 10.1021/Tx049813H |
0.498 |
|
| 2005 |
Seow HA, Belcourt MF, Penketh PG, Hodnick WF, Tomasz M, Rockwell S, Sartorelli AC. Nuclear localization of NADPH:cytochrome c (P450) reductase enhances the cytotoxicity of mitomycin C to Chinese hamster ovary cells. Molecular Pharmacology. 67: 417-23. PMID 15547247 DOI: 10.1124/Mol.104.004929 |
0.465 |
|
| 2004 |
Paz MM, Kumar GS, Glover M, Waring MJ, Tomasz M. Mitomycin dimers: polyfunctional cross-linkers of DNA. Journal of Medicinal Chemistry. 47: 3308-19. PMID 15163210 DOI: 10.1021/Jm049863J |
0.524 |
|
| 2004 |
Seow HA, Penketh PG, Belcourt MF, Tomasz M, Rockwell S, Sartorelli AC. Nuclear overexpression of NAD(P)H:quinone oxidoreductase 1 in Chinese hamster ovary cells increases the cytotoxicity of mitomycin C under aerobic and hypoxic conditions. The Journal of Biological Chemistry. 279: 31606-12. PMID 15155746 DOI: 10.1074/Jbc.M404910200 |
0.449 |
|
| 2003 |
Holtz KM, Rockwell S, Tomasz M, Sartorelli AC. Nuclear overexpression of NADH:cytochrome b5 reductase activity increases the cytotoxicity of mitomycin C (MC) and the total number of MC-DNA adducts in Chinese hamster ovary cells. The Journal of Biological Chemistry. 278: 5029-34. PMID 12424239 DOI: 10.1074/Jbc.M209722200 |
0.45 |
|
| 2002 |
Palom Y, Suresh Kumar G, Tang LQ, Paz MM, Musser SM, Rockwell S, Tomasz M. Relative toxicities of DNA cross-links and monoadducts: new insights from studies of decarbamoyl mitomycin C and mitomycin C. Chemical Research in Toxicology. 15: 1398-406. PMID 12437330 DOI: 10.1021/Tx020044G |
0.525 |
|
| 2002 |
Abbas T, Olivier M, Lopez J, Houser S, Xiao G, Kumar GS, Tomasz M, Bargonetti J. Differential activation of p53 by the various adducts of mitomycin C. The Journal of Biological Chemistry. 277: 40513-9. PMID 12183457 DOI: 10.1074/Jbc.M205495200 |
0.471 |
|
| 2001 |
Paz MM, Tomasz M. Reductive activation of mitomycin A by thiols. Organic Letters. 3: 2789-92. PMID 11529757 DOI: 10.1021/Ol015517+ |
0.34 |
|
| 2001 |
Subramaniam G, Paz MM, Suresh Kumar G, Das A, Palom Y, Clement CC, Patel DJ, Tomasz M. Solution structure of a guanine-N7-linked complex of the mitomycin C metabolite 2,7-diaminomitosene and DNA. Basis of sequence selectivity. Biochemistry. 40: 10473-84. PMID 11523988 DOI: 10.1021/Bi015147X |
0.506 |
|
| 2001 |
Paz MM, Das A, Palom Y, He QY, Tomasz M. Selective activation of mitomycin A by thiols to form DNA cross-links and monoadducts: biochemical basis for the modulation of mitomycin cytotoxicity by the quinone redox potential. Journal of Medicinal Chemistry. 44: 2834-42. PMID 11495594 DOI: 10.1021/Jm010072G |
0.548 |
|
| 2001 |
Palom Y, Belcourt MF, Tang LQ, Mehta SS, Sartorelli AC, Pritsos CA, Pritsos KL, Rockwell S, Tomasz M. Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol. Biochemical Pharmacology. 61: 1517-29. PMID 11377381 DOI: 10.1016/S0006-2952(01)00609-8 |
0.502 |
|
| 2001 |
Subramaniam G, Paz MM, Suresh Kumar G, Das A, Palom Y, Clement CC, Patel DJ, Tomasz M. Solution Structure of a Guanine-N7-Linked Complex of the Mitomycin C Metabolite 2,7-Diaminomitosene and DNA. Basis of Sequence Selectivity, Biochemistry. 40: 12746-12746. DOI: 10.1021/bi015147x |
0.37 |
|
| 2000 |
Palom Y, Belcourt MF, Musser SM, Sartorelli AC, Rockwell S, Tomasz M. Structure of adduct X, the last unknown of the six major DNA adducts of mitomycin C formed in EMT6 mouse mammary tumor cells. Chemical Research in Toxicology. 13: 479-88. PMID 10858321 DOI: 10.1021/Tx000024J |
0.501 |
|
| 1999 |
Paz MM, Das TA, Tomasz M. Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity. Bioorganic & Medicinal Chemistry. 7: 2713-26. PMID 10658576 DOI: 10.1016/S0968-0896(99)00223-0 |
0.548 |
|
| 1999 |
Das A, Tang KS, Gopalakrishnan S, Waring MJ, Tomasz M. Reactivity of guanine at m5CpG steps in DNA: evidence for electronic effects transmitted through the base pairs. Chemistry & Biology. 6: 461-71. PMID 10381403 DOI: 10.1016/S1074-5521(99)80064-7 |
0.447 |
|
| 1999 |
Tomasz M, Das A, Tang KS, Ford MGJ, Minnock A, Musser SM, Waring MJ. The Purine-2-amino Group as the Critical Recognition Element for Sequence-Specific Alkylation and Cross-Linking of DNA by Mitomycin CJ. Am. Chem. Soc.1998,120, 11581−11593 Journal of the American Chemical Society. 121: 1112-1112. DOI: 10.1021/Ja9855388 |
0.411 |
|
| 1998 |
Palom Y, Belcourt MF, Kumar GS, Arai H, Kasai M, Sartorelli AC, Rockwell S, Tomasz M. Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C. Oncology Research. 10: 509-21. PMID 10338154 |
0.458 |
|
| 1998 |
Cummings J, Spanswick VJ, Tomasz M, Smyth JF. Enzymology of mitomycin C metabolic activation in tumour tissue: implications for enzyme-directed bioreductive drug development. Biochemical Pharmacology. 56: 405-14. PMID 9763215 DOI: 10.1016/S0006-2952(98)00073-2 |
0.367 |
|
| 1998 |
Allan JM, Engelward BP, Dreslin AJ, Wyatt MD, Tomasz M, Samson LD. Mammalian 3-methyladenine DNA glycosylase protects against the toxicity and clastogenicity of certain chemotherapeutic DNA cross-linking agents. Cancer Research. 58: 3965-73. PMID 9731510 |
0.377 |
|
| 1998 |
Palom Y, Lipman R, Musser SM, Tomasz M. A mitomycin-N6-deoxyadenosine adduct isolated from DNA. Chemical Research in Toxicology. 11: 203-10. PMID 9544618 DOI: 10.1021/Tx970205U |
0.55 |
|
| 1998 |
Ramos LA, Lipman R, Tomasz M, Basu AK. The major mitomycin C-DNA monoadduct is cytotoxic but not mutagenic in Escherichia coli. Chemical Research in Toxicology. 11: 64-9. PMID 9477227 DOI: 10.1021/Tx970163+ |
0.41 |
|
| 1998 |
Tomasz M, Das A, Tang KS, Ford MGJ, Minnock A, Musser SM, Waring MJ. The purine 2-amino group as the critical recognition element for sequence-specific alkylation and cross-linking of DNA by mitomycin C Journal of the American Chemical Society. 120: 11581-11593. DOI: 10.1021/Ja9824019 |
0.529 |
|
| 1997 |
Tomasz M, Palom Y. The mitomycin bioreductive antitumor agents: cross-linking and alkylation of DNA as the molecular basis of their activity. Pharmacology & Therapeutics. 76: 73-87. PMID 9535170 DOI: 10.1016/S0163-7258(97)00088-0 |
0.548 |
|
| 1997 |
Suresh Kumar G, Lipman R, Cummings J, Tomasz M. Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C. Biochemistry. 36: 14128-36. PMID 9369485 DOI: 10.1021/Bi971394I |
0.522 |
|
| 1997 |
Maliepaard M, de Mol NJ, Tomasz M, Gargiulo D, Janssen LH, van Duynhoven JP, van Velzen EJ, Verboom W, Reinhoudt DN. Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation. Biochemistry. 36: 9211-20. PMID 9230054 DOI: 10.1021/Bi9700680 |
0.582 |
|
| 1996 |
Maruenda H, Tomasz M. Antisense sequence-directed cross-linking of DNA oligonucleotides by mitomycin C. Bioconjugate Chemistry. 7: 541-4. PMID 8889014 DOI: 10.1021/Bc960054R |
0.545 |
|
| 1996 |
Rink SM, Lipman R, Alley SC, Hopkins PB, Tomasz M. Bending of DNA by the mitomycin C-induced, GpG intrastrand cross-link. Chemical Research in Toxicology. 9: 382-9. PMID 8839039 DOI: 10.1021/Tx950156Q |
0.516 |
|
| 1996 |
Kumar GS, Musser SM, Cummings J, Tomasz M. 2,7-Diaminomitosene, a monofunctional mitomycin C derivative, alkylates DNA in the major groove. Structure and base-sequence specificity of the DNA adduct and mechanism of the alkylation Journal of the American Chemical Society. 118: 9209-9217. DOI: 10.1021/Ja9607401 |
0.557 |
|
| 1995 |
Tomasz M. Mitomycin C: small, fast and deadly (but very selective). Chemistry & Biology. 2: 575-9. PMID 9383461 DOI: 10.1016/1074-5521(95)90120-5 |
0.495 |
|
| 1995 |
Gargiulo D, Kumar GS, Musser SS, Tomasz M. Structural and function modification of DNA by mitomycin C. Mechanism of the DNA sequence specificity of mitomycins. Nucleic Acids Symposium Series. 169-70. PMID 8841606 |
0.449 |
|
| 1995 |
Kumar GS, He QY, Behr-Ventura D, Tomasz M. Binding of 2,7-diaminomitosene to DNA: model for the precovalent recognition of DNA by activated mitomycin C. Biochemistry. 34: 2662-71. PMID 7873548 DOI: 10.1021/Bi00008A033 |
0.461 |
|
| 1995 |
Sastry M, Fiala R, Lipman R, Tomasz M, Patel DJ. Solution structure of the monoalkylated mitomycin C-DNA complex. Journal of Molecular Biology. 247: 338-59. PMID 7707379 DOI: 10.1006/Jmbi.1994.0143 |
0.483 |
|
| 1995 |
Johnson WS, He QY, Tomasz M. Selective recognition of the m5CpG dinucleotide sequence in DNA by mitomycin C for alkylation and cross-linking. Bioorganic & Medicinal Chemistry. 3: 851-60. PMID 7582961 DOI: 10.1016/0968-0896(95)00067-Q |
0.525 |
|
| 1995 |
Gargiulo D, Musser SS, Yang L, Fukuyama T, Tomasz M. Alkylation and cross-linking of DNA by the unnatural enantiomer of mitomycin C: Mechanism of the DNA-sequence specificity of mitomycins Journal of the American Chemical Society. 117: 9388-9398. DOI: 10.1021/Ja00142A002 |
0.544 |
|
| 1994 |
Sharma M, He QY, Tomasz M. Effects of glutathione on alkylation and cross-linking of DNA by mitomycin C. Isolation of a ternary glutathione-mitomycin-DNA adduct. Chemical Research in Toxicology. 7: 401-7. PMID 8075372 DOI: 10.1021/Tx00039A018 |
0.573 |
|
| 1994 |
Sharma M, Tomasz M. Conjugation of glutathione and other thiols with bioreductively activated mitomycin C. Effect of thiols on the reductive activation rate. Chemical Research in Toxicology. 7: 390-400. PMID 8075371 DOI: 10.1021/Tx00039A017 |
0.388 |
|
| 1994 |
Tomasz M. DNA adducts of the mitomycins. Iarc Scientific Publications. 349-57. PMID 7806324 |
0.4 |
|
| 1994 |
He QY, Maruenda H, Tomasz M. Novel bioreductive activation mechanism of mitomycin C derivatives bearing a disulfide substituent in their quinone Journal of the American Chemical Society. 116: 9349-9350. DOI: 10.1021/Ja00099A070 |
0.391 |
|
| 1993 |
Basu AK, Hanrahan CJ, Malia SA, Kumar S, Bizanek R, Tomasz M. Effect of site-specifically located mitomycin C-DNA monoadducts on in vitro DNA synthesis by DNA polymerases. Biochemistry. 32: 4708-18. PMID 8490017 DOI: 10.1021/Bi00069A004 |
0.529 |
|
| 1993 |
Kumar S, Johnson WS, Tomasz M. Orientation isomers of the mitomycin C interstrand cross-link in non-self-complementary DNA. Differential effect of the two isomers on restriction endonuclease cleavage at a nearby site. Biochemistry. 32: 1364-72. PMID 8448145 DOI: 10.1021/Bi00056A023 |
0.457 |
|
| 1993 |
Rockwell S, Sartorelli AC, Tomasz M, Kennedy KA. Cellular pharmacology of quinone bioreductive alkylating agents. Cancer Metastasis Reviews. 12: 165-76. PMID 8375019 DOI: 10.1007/Bf00689808 |
0.432 |
|
| 1993 |
Sartorelli AC, Tomasz M, Rockwell S. Studies on the mechanism of the cytotoxic action of the mitomycin antibiotics in hypoxic and oxygenated EMT6 cells. Advances in Enzyme Regulation. 33: 3-17. PMID 8356915 DOI: 10.1016/0065-2571(93)90005-X |
0.423 |
|
| 1993 |
Bizanek R, Chowdary D, Arai H, Kasai M, Hughes CS, Sartorelli AC, Rockwell S, Tomasz M. Adducts of mitomycin C and DNA in EMT6 mouse mammary tumor cells: effects of hypoxia and dicumarol on adduct patterns. Cancer Research. 53: 5127-34. PMID 7693331 |
0.419 |
|
| 1992 |
Kumar S, Lipman R, Tomasz M. Recognition of specific DNA sequences by mitomycin C for alkylation. Biochemistry. 31: 1399-407. PMID 1736997 DOI: 10.1021/Bi00120A016 |
0.455 |
|
| 1992 |
Bizanek R, McGuinness BF, Nakanishi K, Tomasz M. Isolation and structure of an intrastrand cross-link adduct of mitomycin C and DNA. Biochemistry. 31: 3084-91. PMID 1554696 DOI: 10.1021/Bi00127A008 |
0.641 |
|
| 1991 |
McGuinness BF, Lipman R, Goldstein J, Nakanishi K, Tomasz M. Reductive alkylation of DNA by mitomycin A, a mitomycin with high redox potential. Biochemistry. 30: 6444-53. PMID 1905153 DOI: 10.1021/Bi00240A015 |
0.587 |
|
| 1991 |
Tomasz M, Hughes CS, Chowdary D, Keyes SR, Lipman R, Sartorelli AC, Rockwell S. Isolation, identification, and assay of [3H]-porfiromycin adducts of EMT6 mouse mammary tumor cell DNA: effects of hypoxia and dicumarol on adduct patterns. Cancer Communications. 3: 213-23. PMID 1714285 DOI: 10.3727/095535491820873227 |
0.475 |
|
| 1991 |
McGuinness BF, Lipman R, Nakanishi K, Tomasz M. Reaction of sodium dithionite activated mitomycin C with guanine at non-cross-linkable sequences of oligonucleotides Journal of Organic Chemistry. 56: 4826-4829. DOI: 10.1021/Jo00016A005 |
0.603 |
|
| 1990 |
Norman D, Live D, Sastry M, Lipman R, Hingerty BE, Tomasz M, Broyde S, Patel DJ. NMR and computational characterization of mitomycin cross-linked to adjacent deoxyguanosines in the minor groove of the d(T-A-C-G-T-A).d(T-A-C-G-T-A) duplex. Biochemistry. 29: 2861-75. PMID 2346750 DOI: 10.1021/Bi00463A032 |
0.356 |
|
| 1990 |
Borowy-Borowski H, Lipman R, Tomasz M. Recognition between mitomycin C and specific DNA sequences for cross-link formation. Biochemistry. 29: 2999-3006. PMID 2110821 DOI: 10.1021/Bi00464A016 |
0.432 |
|
| 1990 |
Borowy-Borowski H, Lipman R, Chowdary D, Tomasz M. Duplex oligodeoxyribonucleotides cross-linked by mitomycin C at a single site: synthesis, properties, and cross-link reversibility. Biochemistry. 29: 2992-9. PMID 2110820 DOI: 10.1021/Bi00464A015 |
0.449 |
|
| 1988 |
Chawla AK, Tomasz M. Interaction of the antitumor antibiotic mitomycin C with Z-DNA. Journal of Biomolecular Structure & Dynamics. 6: 459-70. PMID 3271532 DOI: 10.1080/07391102.1988.10506500 |
0.521 |
|
| 1988 |
Tomasz M, Chawla AK, Lipman R. Mechanism of monofunctional and bifunctional alkylation of DNA by mitomycin C. Biochemistry. 27: 3182-7. PMID 3134045 DOI: 10.1021/Bi00409A009 |
0.533 |
|
| 1988 |
Tomasz M, Lipman R, McGuinness BF, Nakanishi K. Isolation and characterization of a major adduct between mitomycin C and DNA Journal of the American Chemical Society. 110: 5892-5896. DOI: 10.1021/Ja00225A048 |
0.611 |
|
| 1988 |
McGuinness BF, Nakanishi K, Lipman R, Tomasz M. Synthesis of Guanine Derivatives Substituted in the O6-Position by Mitomycin C Tetrahedron Letters. 29: 4673-4676. DOI: 10.1016/S0040-4039(00)80577-8 |
0.543 |
|
| 1987 |
Tomasz M, Lipman R, Lee MS, Verdine GL, Nakanishi K. Reaction of acid-activated mitomycin C with calf thymus DNA and model guanines: elucidation of the base-catalyzed degradation of N7-alkylguanine nucleosides. Biochemistry. 26: 2010-27. PMID 3109476 DOI: 10.1021/Bi00381A034 |
0.522 |
|
| 1987 |
Tomasz M, Lipman R, Chowdary D, Pawlak J, Verdine GL, Nakanishi K. Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science (New York, N.Y.). 235: 1204-8. PMID 3103215 DOI: 10.1126/Science.3103215 |
0.637 |
|
| 1987 |
Verdine GL, McGuinness BF, Nakanishi K, Tomasz M. Unusual CIS stereoselectivity in an aziridine cleavage reaction of mitomycin C Heterocycles. 25: 577-587. DOI: 10.3987/S-1987-01-0577 |
0.467 |
|
| 1986 |
Sutherland JC, Lin BH, Mugavero J, Trunk J, Tomasz M, Santella R, Marky L, Breslauer KJ. Vacuum ultraviolet circular dichroism of double stranded nucleic acids. Photochemistry and Photobiology. 44: 295-301. PMID 3786449 DOI: 10.1111/J.1751-1097.1986.Tb04667.X |
0.307 |
|
| 1986 |
Tomasz M, Lipman R, Verdine GL, Nakanishi K. Reassignment of the guanine-binding mode of reduced mitomycin C. Biochemistry. 25: 4337-44. PMID 3092855 DOI: 10.1021/Bi00363A024 |
0.565 |
|
| 1986 |
Tomasz M, Chowdary D, Lipman R, Shimotakahara S, Veiro D, Walker V, Verdine GL. Reaction of DNA with chemically or enzymatically activated mitomycin C: isolation and structure of the major covalent adduct. Proceedings of the National Academy of Sciences of the United States of America. 83: 6702-6. PMID 3018744 DOI: 10.1073/Pnas.83.18.6702 |
0.567 |
|
| 1985 |
Tomasz M, Lipman R, Verdine G, Nakanishi K. Nature of the destruction of deoxyguanosine residues by mitomycin C Journal of the American Chemical Society. 107: 6120-6121. DOI: 10.1021/Ja00307A057 |
0.501 |
|
| 1985 |
Tomasz M, Lipman R, Verdine GL, Nakanishi K. Nature of the destruction of deoxyguanosine residues by mitomycin C activated by mild acid pH Journal of the American Chemical Society. 107: 6120-6123. DOI: 10.1002/Chin.198605105 |
0.477 |
|
| 1984 |
Tomasz M, Jung M, Verdine G, Nakanishi K. Circular dichroism spectroscopy as a probe for the stereochemistry of aziridine cleavage reactions of mitomycin C. Application to adducts of mitomycin with DNA constituents Journal of the American Chemical Society. 106: 7367-7370. DOI: 10.1021/Ja00336A012 |
0.61 |
|
| 1983 |
Tomasz M, Barton JK, Magliozzo CC, Tucker D, Lafer EM, Stollar BD. Lack of Z-DNA conformation in mitomycin-modified polynucleotides having inverted circular dichroism. Proceedings of the National Academy of Sciences of the United States of America. 80: 2874-8. PMID 6574457 DOI: 10.1073/Pnas.80.10.2874 |
0.461 |
|
| 1983 |
Tomasz M, Lipman R, Snyder JK, Nakanishi K. Full structure of a mitomycin C dinucleoside phosphate adduct. Use of differential FT-IR spectroscopy in microscale structural studies Journal of the American Chemical Society. 105: 2059-2063. DOI: 10.1021/Ja00345A065 |
0.458 |
|
| 1982 |
Weaver J, Tomasz M. Reactivity of mitomycin C with synthetic polyribonucleotides containing guanine or guanine analogs. Biochimica Et Biophysica Acta. 697: 252-4. PMID 6809051 DOI: 10.1016/0167-4781(82)90084-7 |
0.381 |
|
| 1982 |
Kaplan DJ, Tomasz M. Altered physiochemical properties of the deoxyribonucleic acid-mitomycin C complex. Evidence for the conformational change in deoxyribonucleic acid. Biochemistry. 21: 3006-13. PMID 6809044 DOI: 10.1021/Bi00541A031 |
0.533 |
|
| 1982 |
Tomasz M, Tucker D, Lipman R. Nuclease-resistant oligonucleotides with 'inverted' circular dichroism isolated from poly [d(G-C)].poly [d(G-C)] and M. lysodeicticus DNA after modification by mitomycin C Federation Proceedings. 41: No. 5432. |
0.307 |
|
| 1981 |
Tomasz M, Lipman R. Reductive metabolism and alkylating activity of mitomycin C induced by rat liver microsomes. Biochemistry. 20: 5056-61. PMID 6794605 DOI: 10.1021/Bi00520A036 |
0.42 |
|
| 1979 |
Tomasz M, Lipman R. Alkylation reactions of mitomycin C at acid pH Journal of the American Chemical Society. 101: 6063-6067. DOI: 10.1021/Ja00514A032 |
0.351 |
|
| 1978 |
Lipman R, Weaver J, Tomasz M. Electrostatic complexes of mitomycin C with nucleic acids and polyanions. Biochimica Et Biophysica Acta. 521: 779-91. PMID 737186 DOI: 10.1016/0005-2787(78)90317-9 |
0.415 |
|
| 1978 |
LaRusso NF, Tomasz M, Kaplan D, Müller M. Absence of strand breaks in deoxyribonucleic acid treated with metronidazole. Antimicrobial Agents and Chemotherapy. 13: 19-24. PMID 626487 DOI: 10.1128/Aac.13.1.19 |
0.491 |
|
| 1977 |
Mercado CM, Tomasz M. Circular dichroism of mitomycin-DNA complexes. Evidence for a conformational change in DNA. Biochemistry. 16: 2040-6. PMID 322710 DOI: 10.1021/Bi00628A044 |
0.47 |
|
| 1976 |
Tomasz M. H2O2 generation during the redox cycle of mitomycin C and dna-bound mitomycin C. Chemico-Biological Interactions. 13: 89-97. PMID 770011 DOI: 10.1016/0009-2797(76)90016-8 |
0.487 |
|
| 1974 |
Tomasz M, Mercado CM, Olson J, Chatterjie N. The mode of interaction of mitomycin C with deoxyribonucleic acid and other polynucleotides in vitro. Biochemistry. 13: 4878-87. PMID 4373040 DOI: 10.1021/Bi00721A002 |
0.32 |
|
| 1972 |
Tomasz M, Olson J, Mercado CM. Mechanism of the isotopic exchange of the C-8 hydrogen of purines in nucleosides and in deoxyribonucleic acid. Biochemistry. 11: 1235-41. PMID 5012976 DOI: 10.1021/Bi00757A019 |
0.337 |
|
| 1972 |
Mercado CM, Tomasz M. Inhibitory effects of mitomycin-related compounds lacking the C1-C2 aziridine ring. Antimicrobial Agents and Chemotherapy. 1: 73-7. PMID 4670432 DOI: 10.1128/Aac.1.1.73 |
0.406 |
|
| 1970 |
Tomasz M. Novel assay of 7-alkylation of guanine residues in DNA. Application to nitrogen mustard, triethylenemelamine and mitomycin C. Biochimica Et Biophysica Acta. 213: 288-95. PMID 4396270 DOI: 10.1016/0005-2787(70)90037-7 |
0.521 |
|
| 1970 |
Tomasz M. Extreme lability of the C-8 proton: a consequence of 7-methylation of guanine residues in model compounds and in DNA and its analytical application. Biochimica Et Biophysica Acta. 199: 18-28. PMID 4391764 DOI: 10.1016/0005-2787(70)90690-8 |
0.495 |
|
| 1966 |
Tomasz M, Chambers RW. The chemistry of pseudouridine. VII. Selective cleavage of polynucleotides containing pseudouridylic acid residues by a unique photochemical reaction. Biochemistry. 5: 773-82. PMID 5940960 DOI: 10.1021/Bi00866A052 |
0.307 |
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| 1964 |
Stork G, Tomasz M. A New Synthesis of Cyclohexenones: The Double Michael Addition of Vinyl Ethynyl Ketones to Active Methylene Compounds. Application to the Total Synthesis ofdl-Griseofulvin Journal of the American Chemical Society. 86: 471-478. DOI: 10.1021/Ja01057A038 |
0.496 |
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| 1962 |
Stork G, Tomasz M. A Stereospecific Total Synthesis of Griseofulvin Journal of the American Chemical Society. 84: 310-312. DOI: 10.1021/Ja00861A040 |
0.472 |
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