Yousong Ding, Ph.D. - Publications

Affiliations: 
2010 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
cryptophycin anticancer drugs

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Tang Q, Ratnayake R, Seabra G, Jiang Z, Fang R, Cui L, Ding Y, Kahveci T, Bian J, Li C, Luesch H, Li Y. Morphological profiling for drug discovery in the era of deep learning. Briefings in Bioinformatics. 25. PMID 38886164 DOI: 10.1093/bib/bbae284  0.474
2024 Kallifidas D, Dhakal D, Chen M, Chen QY, Kokkaliari S, Colon Rosa NA, Ratnayake R, Bruner SD, Paul VJ, Ding Y, Luesch H. Biosynthesis of Dolastatin 10 in Marine Cyanobacteria, a Prototype for Multiple Approved Cancer Drugs. Organic Letters. PMID 38330916 DOI: 10.1021/acs.orglett.3c04083  0.707
2023 Tang Q, Ratnayake R, Seabra G, Jiang Z, Fang R, Cui L, Ding Y, Kahveci T, Bian J, Li C, Luesch H, Li Y. Morphological Profiling for Drug Discovery in the Era of Deep Learning. Arxiv. PMID 38168460  0.474
2023 Dhakal D, Kallifidas D, Chen M, Kokkaliari S, Chen QY, Paul VJ, Ding Y, Luesch H. Heterologous Production of the C33-C45 Polyketide Fragment of Anticancer Apratoxins in a Cyanobacterial Host. Organic Letters. PMID 36961224 DOI: 10.1021/acs.orglett.3c00462  0.71
2022 Dhakal D, Kokkaliari S, Rubin GM, Paul VJ, Ding Y, Luesch H. Biosynthesis of Lyngbyastatins 1 and 3, Cytotoxic Depsipeptides from an sp. Marine Cyanobacterium. Journal of Natural Products. PMID 36546857 DOI: 10.1021/acs.jnatprod.2c00782  0.728
2021 Liu D, Rubin GM, Dhakal D, Chen M, Ding Y. Biocatalytic synthesis of peptidic natural products and related analogues. Iscience. 24: 102512. PMID 34041453 DOI: 10.1016/j.isci.2021.102512  0.674
2021 Dhakal D, Chen M, Luesch H, Ding Y. Heterologous production of cyanobacterial compounds. Journal of Industrial Microbiology & Biotechnology. PMID 33928376 DOI: 10.1093/jimb/kuab003  0.719
2021 Yang H, Kundra S, Chojnacki M, Liu K, Fuse MA, Abouelhassan Y, Kallifidas D, Zhang P, Huang G, Jin S, Ding Y, Luesch H, Rohde KH, Dunman PM, Lemos JA, et al. A Modular Synthetic Route Involving -Aryl-2-nitrosoaniline Intermediates Leads to a New Series of 3-Substituted Halogenated Phenazine Antibacterial Agents. Journal of Medicinal Chemistry. PMID 33881312 DOI: 10.1021/acs.jmedchem.1c00168  0.506
2020 Jiang G, Zhang P, Ratnayake R, Yang G, Zhang Y, Zuo R, Powell M, Huguet-Tapia JC, Abboud KA, Dang LH, Teplitski M, Paul V, Xiao R, Zaman KAU, Hu Z, ... ... Ding Y, et al. Fungal epithiodiketopiperazines carrying α,β-polysulfide bridges from Penecillium steckii YE, and their chemical interconversion. Chembiochem : a European Journal of Chemical Biology. PMID 32816319 DOI: 10.1002/Cbic.202000403  0.576
2020 Zhang P, MacTavish BS, Yang G, Chen M, Roh J, Newsome KR, Bruner SD, Ding Y. Cyanobacterial Dihydroxyacid Dehydratases Are a Promising Growth Inhibition Target. Acs Chemical Biology. PMID 32786290 DOI: 10.1021/Acschembio.0C00507  0.341
2020 Rubin GM, Ding Y. Recent advances in the biosynthesis of RiPPs from multicore-containing precursor peptides. Journal of Industrial Microbiology & Biotechnology. PMID 32617877 DOI: 10.1007/S10295-020-02289-1  0.349
2020 Wang F, Sarotti AM, Jiang G, Huguet-Tapia JC, Zheng SL, Wu X, Li C, Ding Y, Cao S. Waikikiamides A-C: Complex Diketopiperazine Dimer and Diketopiperazine-Polyketide Hybrids from a Hawaiian Marine Fungal Strain sp. FM242. Organic Letters. PMID 32433885 DOI: 10.1021/Acs.Orglett.0C01411  0.38
2019 Zuo R, Ding Y. Direct Aromatic Nitration System for Synthesis of Nitrotryptophans in Escherichia coli. Acs Synthetic Biology. PMID 30865826 DOI: 10.1021/Acssynbio.8B00534  0.327
2019 Gunasekera SP, Meyer JL, Ding Y, Abboud KA, Luo D, Campbell JE, Angerhofer A, Goodsell JL, Raymundo LJ, Liu J, Ye T, Luesch H, Teplitski M, Paul VJ. Chemical and Metagenomic Studies of the Lethal Black Band Disease of Corals Reveal Two Broadly Distributed, Redox-Sensitive Mixed Polyketide/Peptide Macrocycles. Journal of Natural Products. PMID 30636420 DOI: 10.1021/Acs.Jnatprod.8B00804  0.571
2019 Jiang G, Zhang Y, Powell MM, Hylton SM, Hiller NW, Loria R, Ding Y. A Promiscuous Cytochrome P450 Hydroxylates Aliphatic and Aromatic C-H Bonds of Aromatic 2,5-Diketopiperazines. Chembiochem : a European Journal of Chemical Biology. PMID 30604585 DOI: 10.1002/Cbic.201800736  0.333
2018 Zhang Y, Chen M, Bruner SD, Ding Y. Heterologous Production of Microbial Ribosomally Synthesized and Post-translationally Modified Peptides. Frontiers in Microbiology. 9: 1801. PMID 30135682 DOI: 10.3389/Fmicb.2018.01801  0.412
2018 Hanson AD, Amthor JS, Sun J, Niehaus TD, Gregory JF, Bruner SD, Ding Y. Redesigning thiamin synthesis: Prospects and potential payoffs. Plant Science : An International Journal of Experimental Plant Biology. 273: 92-99. PMID 29907313 DOI: 10.1016/J.Plantsci.2018.01.019  0.309
2018 Zhang Y, Li K, Yang G, McBride JL, Bruner SD, Ding Y. A distributive peptide cyclase processes multiple microviridin core peptides within a single polypeptide substrate. Nature Communications. 9: 1780. PMID 29725007 DOI: 10.1038/S41467-018-04154-3  0.311
2018 Jiang G, Zhang Y, Powell MM, Zhang P, Zuo R, Zhang Y, Kallifidas D, Tieu AM, Luesch H, Loria R, Ding Y. High-yield production of herbicidal thaxtomins and analogs in a nonpathogenicstrain. Applied and Environmental Microbiology. PMID 29602787 DOI: 10.1128/Aem.00164-18  0.619
2018 Kallifidas D, Jiang G, Ding Y, Luesch H. Rational engineering of Streptomyces albus J1074 for the overexpression of secondary metabolite gene clusters. Microbial Cell Factories. 17: 25. PMID 29454348 DOI: 10.1186/S12934-018-0874-2  0.593
2018 Zhang Y, Jiang G, Ding Y, Loria R. Genetic background affects pathogenicity island function and pathogen emergence in Streptomyces. Molecular Plant Pathology. PMID 29316196 DOI: 10.1111/Mpp.12656  0.32
2018 Yang G, Cozad MA, Holland DA, Zhang Y, Luesch H, Ding Y. Photosynthetic production of sunscreen shinorine using an engineered cyanobacterium. Acs Synthetic Biology. PMID 29304277 DOI: 10.1021/Acssynbio.7B00397  0.62
2018 Jiang G, Zuo R, Zhang Y, Powell MM, Zhang P, Hylton SM, Loria R, Ding Y. One-Pot Biocombinatorial Synthesis of Herbicidal Thaxtomins Acs Catalysis. 8: 10761-10768. DOI: 10.1021/Acscatal.8B03317  0.377
2017 Yang G, Zhang Y, Lee NK, Cozad MA, Kearney SE, Luesch H, Ding Y. Cyanobacterial Sfp-type phosphopantetheinyl transferases functionalize carrier proteins of diverse biosynthetic pathways. Scientific Reports. 7: 11888. PMID 28928426 DOI: 10.1038/S41598-017-12244-3  0.603
2017 Zhang P, Li K, Yang G, Xia C, Polston JE, Li G, Li S, Lin Z, Yang LJ, Bruner SD, Ding Y. Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784797 DOI: 10.1073/Pnas.1706894114  0.303
2017 Basak A, Abouelhassan Y, Zuo R, Yousaf H, Ding Y, Huigens RW. Antimicrobial peptide-inspired NH125 analogues: bacterial and fungal biofilm-eradicating agents and rapid killers of MRSA persisters. Organic & Biomolecular Chemistry. PMID 28534905 DOI: 10.1039/C7Ob01028A  0.341
2017 Zuo R, Zhang Y, Jiang C, Hackett JC, Loria R, Bruner SD, Ding Y. Engineered P450 biocatalysts show improved activity and regio-promiscuity in aromatic nitration. Scientific Reports. 7: 842. PMID 28405004 DOI: 10.1038/S41598-017-00897-Z  0.344
2016 Li K, Condurso HL, Li G, Ding Y, Bruner SD. Structural basis for precursor protein-directed ribosomal peptide macrocyclization. Nature Chemical Biology. PMID 27669417 DOI: 10.1038/Nchembio.2200  0.365
2016 Zuo R, Garrison AT, Basak A, Zhang P, Huigens RW, Ding Y. In vitro antifungal and antibiofilm activities of halogenated quinoline analogues against Candida albicans and Cryptococcus neoformans. International Journal of Antimicrobial Agents. PMID 27256584 DOI: 10.1016/J.Ijantimicag.2016.04.019  0.319
2016 Zuo R, Zhang Y, Huguet-Tapia JC, Mehta M, Dedic E, Bruner SD, Loria R, Ding Y. An artificial self-sufficient cytochrome P450 directly nitrates fluorinated tryptophan analogs with a different regio-selectivity. Biotechnology Journal. PMID 26743860 DOI: 10.1002/Biot.201500416  0.369
2016 Le J, Gao Y, Ding Y, Jiang C. Cu-mediated C2-dehydrogenative homocoupling of indoles via C-H activation assisted by a removable N-pyrimidyl group Tetrahedron Letters. 57: 1728-1731. DOI: 10.1016/J.Tetlet.2016.03.027  0.301
2016 He YC, Liu F, Di JH, Ding Y, Zhu ZZ, Wu YQ, Chen L, Wang C, Xue YF, Chong GG, Ma CL. Effective enzymatic saccharification of dilute NaOH extraction of chestnut shell pretreated by acidified aqueous ethylene glycol media Industrial Crops and Products. 81: 129-138. DOI: 10.1016/j.indcrop.2015.11.079  0.357
2015 Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Ferroli RB, Ban Y, Bennett DW, Bennett JV, Bertani M, ... Ding Y, et al. Observation of a Neutral Structure near the DD[over ¯]^{*} Mass Threshold in e^{+}e^{-}→(DD[over ¯]^{*})^{0}π^{0} at sqrt[s]=4.226 and 4.257 GeV. Physical Review Letters. 115: 222002. PMID 26650295 DOI: 10.1103/Physrevlett.115.222002  0.367
2015 Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Baldini Ferroli R, Ban Y, Bennett DW, Bennett JV, Bertani M, ... Ding Y, et al. Measurement of the Absolute Branching Fraction for Λ_{c}^{+}→Λe^{+}ν_{e}. Physical Review Letters. 115: 221805. PMID 26650293 DOI: 10.1103/Physrevlett.115.221805  0.366
2015 Xue Y, Ding Y, Niu J, Xia Z, Roy A, Chen H, Qu J, Wang ZL, Dai L. Rationally designed graphene-nanotube 3D architectures with a seamless nodal junction for efficient energy conversion and storage. Science Advances. 1: e1400198. PMID 26601246 DOI: 10.1126/Sciadv.1400198  0.371
2015 Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Ferroli RB, Ban Y, Bennett DW, Bennett JV, Bertani M, ... Ding Y, et al. Observation of a Neutral Charmoniumlike State Z_{c}(4025)^{0} in e^{+}e^{-}→(D^{*}D[over ¯]^{*})^{0}π^{0}. Physical Review Letters. 115: 182002. PMID 26565461 DOI: 10.1103/Physrevlett.115.182002  0.354
2014 Yang G, Ding Y. Recent advances in biocatalyst discovery, development and applications. Bioorganic & Medicinal Chemistry. 22: 5604-12. PMID 25042559 DOI: 10.1016/J.Bmc.2014.06.033  0.324
2011 Ding Y, Rath CM, Bolduc KL, Håkansson K, Sherman DH. Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module. Journal of the American Chemical Society. 133: 14492-5. PMID 21823639 DOI: 10.1021/Ja204716F  0.741
2010 Ding Y, de Wet JR, Cavalcoli J, Li S, Greshock TJ, Miller KA, Finefield JM, Sunderhaus JD, McAfoos TJ, Tsukamoto S, Williams RM, Sherman DH. Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived Aspergillus sp. Journal of the American Chemical Society. 132: 12733-40. PMID 20722388 DOI: 10.1021/Ja1049302  0.698
2010 Ding Y, Sherman DH. The role of synthesis and biosynthetic logic Comprehensive Natural Products Ii: Chemistry and Biology. 2: 559-579.  0.417
2008 Ding Y, Greshock TJ, Miller KA, Sherman DH, Williams RM. Premalbrancheamide: synthesis, isotopic labeling, biosynthetic incorporation, and detection in cultures of Malbranchea aurantiaca. Organic Letters. 10: 4863-6. PMID 18844365 DOI: 10.1021/Ol8019633  0.438
2008 Ding Y, Gruschow S, Greshock TJ, Finefield JM, Sherman DH, Williams RM. Detection of VM55599 and preparaherquamide from Aspergillus japonicus and Penicillium fellutanum: biosynthetic implications. Journal of Natural Products. 71: 1574-8. PMID 18754595 DOI: 10.1021/Np800292N  0.476
2008 Ding Y, Williams RM, Sherman DH. Molecular analysis of a 4-dimethylallyltryptophan synthase from Malbranchea aurantiaca. The Journal of Biological Chemistry. 283: 16068-76. PMID 18390548 DOI: 10.1074/Jbc.M801991200  0.571
2008 Ding Y, Seufert WH, Beck ZQ, Sherman DH. Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativity. Journal of the American Chemical Society. 130: 5492-8. PMID 18366166 DOI: 10.1021/Ja710520Q  0.547
2008 Miller KA, Welch TR, Greshock TJ, Ding Y, Sherman DH, Williams RM. Biomimetic total synthesis of malbrancheamide and malbrancheamide B. The Journal of Organic Chemistry. 73: 3116-9. PMID 18345688 DOI: 10.1021/Jo800116Y  0.506
2008 Miller KA, Welch TR, Greshock TJ, Ding Y, Sherman DH, Williams RM. ChemInform Abstract: Biomimetic Total Synthesis of Malbrancheamide (IVa) and Malbrancheamide B (IVb). Cheminform. 39. DOI: 10.1002/chin.200835187  0.405
2006 Magarvey NA, Beck ZQ, Golakoti T, Ding Y, Huber U, Hemscheidt TK, Abelson D, Moore RE, Sherman DH. Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts. Acs Chemical Biology. 1: 766-79. PMID 17240975 DOI: 10.1021/Cb6004307  0.724
2005 Ding K, Lu Y, Nikolovska-Coleska Z, Qiu S, Ding Y, Gao W, Stuckey J, Krajewski K, Roller PP, Tomita Y, Parrish DA, Deschamps JR, Wang S. Structure-based design of potent non-peptide MDM2 inhibitors. Journal of the American Chemical Society. 127: 10130-1. PMID 16028899 DOI: 10.1021/Ja051147Z  0.314
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