Bradley J. Nolen, Ph.D. - Publications
Affiliations: | 2003 | University of California, San Diego, La Jolla, CA |
Area:
transcription, signaling, pre-mRNA splicing, mRNA transport, protein-protein, protein-DNA and protein-RNA interactionsYear | Citation | Score | |||
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2013 | Luan Q, Nolen BJ. Structural basis for regulation of Arp2/3 complex by GMF. Nature Structural & Molecular Biology. 20: 1062-8. PMID 23893131 DOI: 10.1038/nsmb.2628 | 0.34 | |||
2013 | Hetrick B, Han MS, Helgeson LA, Nolen BJ. Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. Chemistry & Biology. 20: 701-12. PMID 23623350 DOI: 10.1016/J.Chembiol.2013.03.019 | 0.389 | |||
2012 | Baggett AW, Cournia Z, Han MS, Patargias G, Glass AC, Liu SY, Nolen BJ. Structural characterization and computer-aided optimization of a small-molecule inhibitor of the Arp2/3 complex, a key regulator of the actin cytoskeleton. Chemmedchem. 7: 1286-94. PMID 22623398 DOI: 10.1002/Cmdc.201200104 | 0.311 | |||
2011 | Ti SC, Jurgenson CT, Nolen BJ, Pollard TD. Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex. Proceedings of the National Academy of Sciences of the United States of America. 108: E463-71. PMID 21676862 DOI: 10.1073/Pnas.1100125108 | 0.32 | |||
2009 | Zencheck WD, Xiao H, Nolen BJ, Angeletti RH, Pollard TD, Almo SC. Nucleotide- and activator-dependent structural and dynamic changes of arp2/3 complex monitored by hydrogen/deuterium exchange and mass spectrometry. Journal of Molecular Biology. 390: 414-27. PMID 19298826 DOI: 10.1016/J.Jmb.2009.03.028 | 0.392 | |||
2008 | Dalhaimer P, Pollard TD, Nolen BJ. Nucleotide-mediated conformational changes of monomeric actin and Arp3 studied by molecular dynamics simulations. Journal of Molecular Biology. 376: 166-83. PMID 18155236 DOI: 10.1016/J.Jmb.2007.11.068 | 0.303 | |||
2007 | Nolen BJ, Pollard TD. Insights into the influence of nucleotides on actin family proteins from seven structures of Arp2/3 complex. Molecular Cell. 26: 449-57. PMID 17499050 DOI: 10.1016/J.Molcel.2007.04.017 | 0.376 | |||
2004 | Nolen BJ, Littlefield RS, Pollard TD. Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP. Proceedings of the National Academy of Sciences of the United States of America. 101: 15627-32. PMID 15505213 DOI: 10.1073/Pnas.0407149101 | 0.37 | |||
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