Chris Sander, PhD - Publications

Affiliations: 
1986-1997 Biocomputing EMBL Heidelberg 
 1995-1998 Research European Bioinformatics Institute (EBI), UK 
 2002-2015 Computational Biology Center Memorial Sloan Kettering Cancer Center, Rockville Centre, NY, United States 
 2016- Cell Biology Harvard Medical School 
Area:
computational biology, structural biology, cancer biology, evolutionary biology
Website:
http://sanderlab.org

315 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Fram B, Su Y, Truebridge I, Riesselman AJ, Ingraham JB, Passera A, Napier E, Thadani NN, Lim S, Roberts K, Kaur G, Stiffler MA, Marks DS, Bahl CD, Khan AR, ... Sander C, et al. Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Nature Communications. 15: 5141. PMID 38902262 DOI: 10.1038/s41467-024-49119-x  0.577
2024 Notin P, Rollins N, Gal Y, Sander C, Marks D. Machine learning for functional protein design. Nature Biotechnology. 42: 216-228. PMID 38361074 DOI: 10.1038/s41587-024-02127-0  0.552
2024 Peidli S, Green TD, Shen C, Gross T, Min J, Garda S, Yuan B, Schumacher LJ, Taylor-King JP, Marks DS, Luna A, Blüthgen N, Sander C. scPerturb: harmonized single-cell perturbation data. Nature Methods. PMID 38279009 DOI: 10.1038/s41592-023-02144-y  0.525
2023 Thadani NN, Gurev S, Notin P, Youssef N, Rollins NJ, Ritter D, Sander C, Gal Y, Marks DS. Learning from prepandemic data to forecast viral escape. Nature. 622: 818-825. PMID 37821700 DOI: 10.1038/s41586-023-06617-0  0.532
2023 Fram B, Truebridge I, Su Y, Riesselman AJ, Ingraham JB, Passera A, Napier E, Thadani NN, Lim S, Roberts K, Kaur G, Stiffler M, Marks DS, Bahl CD, Khan AR, ... Sander C, et al. Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Biorxiv : the Preprint Server For Biology. PMID 37214973 DOI: 10.1101/2023.05.09.539914  0.576
2023 Placido D, Yuan B, Hjaltelin JX, Zheng C, Haue AD, Chmura PJ, Yuan C, Kim J, Umeton R, Antell G, Chowdhury A, Franz A, Brais L, Andrews E, Marks DS, ... ... Sander C, et al. A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories. Nature Medicine. PMID 37156936 DOI: 10.1038/s41591-023-02332-5  0.506
2022 Yan G, Luna A, Wang H, Bozorgui B, Li X, Sanchez M, Dereli Z, Kahraman N, Kara G, Chen X, Zheng C, McGrail D, Sahni N, Lu Y, Babur O, ... ... Sander C, et al. BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer. Cell Reports. 40: 111304. PMID 36103824 DOI: 10.1016/j.celrep.2022.111304  0.774
2022 Li X, Dowling EK, Yan G, Dereli Z, Bozorgui B, Imanirad P, Elnaggar JH, Luna A, Menter DG, Pilie PG, Yap TA, Kopetz S, Sander C, Korkut A. Precision combination therapies based on recurrent oncogenic co-alterations. Cancer Discovery. PMID 35412613 DOI: 10.1158/2159-8290.CD-21-0832  0.721
2021 Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, Singh V, Aghamiri SS, Acencio ML, Glaab E, Ruepp A, Fobo G, Montrone C, Brauner B, Frishman G, ... ... Sander C, et al. COVID-19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms. Molecular Systems Biology. 17: e10851. PMID 34939300 DOI: 10.15252/msb.202110851  0.756
2021 Luna A, Siper MC, Korkut A, Durupinar F, Dogrusoz U, Aslan JE, Sander C, Demir E, Babur O. Analyzing causal relationships in proteomic profiles using CausalPath. Star Protocols. 2: 100955. PMID 34877547 DOI: 10.1016/j.xpro.2021.100955  0.765
2021 Wong JV, Franz M, Siper MC, Fong D, Durupinar F, Dallago C, Luna A, Giorgi JM, Rodchenkov I, Babur Ö, Bachman JA, Gyori B, Demir E, Bader GD, Sander C. Author-sourced capture of pathway knowledge in computable form using Biofactoid. Elife. 10. PMID 34860157 DOI: 10.7554/eLife.68292  0.721
2021 Gillespie M, Jassal B, Stephan R, Milacic M, Rothfels K, Senff-Ribeiro A, Griss J, Sevilla C, Matthews L, Gong C, Deng C, Varusai T, Ragueneau E, Haider Y, May B, ... ... Sander C, et al. The reactome pathway knowledgebase 2022. Nucleic Acids Research. PMID 34788843 DOI: 10.1093/nar/gkab1028  0.488
2021 Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, Singh V, Aghamiri SS, Acencio ML, Glaab E, Ruepp A, Fobo G, Montrone C, Brauner B, Frishman G, ... ... Sander C, et al. COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms. Molecular Systems Biology. 17: e10387. PMID 34664389 DOI: 10.15252/msb.202110387  0.78
2021 Babur Ö, Luna A, Korkut A, Durupinar F, Siper MC, Dogrusoz U, Vaca Jacome AS, Peckner R, Christianson KE, Jaffe JD, Spellman PT, Aslan JE, Sander C, Demir E. Causal interactions from proteomic profiles: Molecular data meet pathway knowledge. Patterns (New York, N.Y.). 2: 100257. PMID 34179843 DOI: 10.1016/j.patter.2021.100257  0.761
2021 Bernhofer M, Dallago C, Karl T, Satagopam V, Heinzinger M, Littmann M, Olenyi T, Qiu J, Schütze K, Yachdav G, Ashkenazy H, Ben-Tal N, Bromberg Y, Goldberg T, Kajan L, ... ... Sander C, et al. PredictProtein - Predicting Protein Structure and Function for 29 Years. Nucleic Acids Research. PMID 33999203 DOI: 10.1093/nar/gkab354  0.812
2021 Shin JE, Riesselman AJ, Kollasch AW, McMahon C, Simon E, Sander C, Manglik A, Kruse AC, Marks DS. Protein design and variant prediction using autoregressive generative models. Nature Communications. 12: 2403. PMID 33893299 DOI: 10.1038/s41467-021-22732-w  0.559
2020 Yuan B, Shen C, Luna A, Korkut A, Marks DS, Ingraham J, Sander C. CellBox: Interpretable Machine Learning for Perturbation Biology with Application to the Design of Cancer Combination Therapy. Cell Systems. PMID 33373583 DOI: 10.1016/j.cels.2020.11.013  0.691
2020 Reguant R, Antipin Y, Sheridan R, Dallago C, Diamantoukos D, Luna A, Sander C, Gauthier NP. AlignmentViewer: Sequence Analysis of Large Protein Families. F1000research. 9. PMID 33123346 DOI: 10.12688/F1000Research.22242.1  0.359
2020 Nyman E, Stein RR, Jing X, Wang W, Marks B, Zervantonakis IK, Korkut A, Gauthier NP, Sander C. Perturbation biology links temporal protein changes to drug responses in a melanoma cell line. Plos Computational Biology. 16: e1007909. PMID 32667922 DOI: 10.1371/Journal.Pcbi.1007909  0.631
2020 Shen J, Yuan B, Luna A, Korkut A, Marks D, Ingraham J, Sander C. Abstract 2102: Interpretable machine learning for perturbation biology Cancer Research. 80: 2102-2102. DOI: 10.1158/1538-7445.Am2020-2102  0.716
2019 Stiffler MA, Poelwijk FJ, Brock KP, Stein RR, Riesselman A, Teyra J, Sidhu SS, Marks DS, Gauthier NP, Sander C. Protein Structure from Experimental Evolution. Cell Systems. PMID 31838147 DOI: 10.1016/J.Cels.2019.11.008  0.625
2019 Guo T, Luna A, Rajapakse VN, Koh CC, Wu Z, Liu W, Sun Y, Gao H, Menden MP, Xu C, Calzone L, Martignetti L, Auwerx C, Buljan M, Banaei-Esfahani A, ... ... Sander C, et al. Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines. Iscience. 21: 664-680. PMID 31733513 DOI: 10.1016/J.Isci.2019.10.059  0.512
2019 Rodchenkov I, Babur O, Luna A, Aksoy BA, Wong JV, Fong D, Franz M, Siper MC, Cheung M, Wrana M, Mistry H, Mosier L, Dlin J, Wen Q, O'Callaghan C, ... ... Sander C, et al. Pathway Commons 2019 Update: integration, analysis and exploration of pathway data. Nucleic Acids Research. PMID 31647099 DOI: 10.1093/Nar/Gkz946  0.792
2019 Sala D, Huang YJ, Cole CA, Snyder D, Liu G, Ishida Y, Swapna GVT, Brock KP, Sander C, Fidelis K, Kryshtafovych A, Inouye M, Tejero R, Valafar H, Rosato A, et al. Protein Structure Prediction Assisted with Sparse NMR Data in CASP13. Proteins. PMID 31603581 DOI: 10.1002/Prot.25837  0.352
2019 Vedanayagam J, Chatila WK, Aksoy BA, Majumdar S, Skanderup AJ, Demir E, Schultz N, Sander C, Lai EC. Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis. Nature Communications. 10: 3682. PMID 31417090 DOI: 10.1038/S41467-019-11610-1  0.675
2019 Rollins NJ, Brock KP, Poelwijk FJ, Stiffler MA, Gauthier NP, Sander C, Marks DS. Inferring protein 3D structure from deep mutation scans. Nature Genetics. PMID 31209393 DOI: 10.1038/S41588-019-0432-9  0.608
2019 Xu J, Reznik E, Lee HJ, Gundem G, Jonsson P, Sarungbam J, Bialik A, Sanchez-Vega F, Creighton CJ, Hoekstra JG, Zhang L, Sajjakulnukit P, Kremer D, Tolstyka ZP, Casuscelli J, ... ... Sander C, et al. Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma. Elife. 8. PMID 30924768 DOI: 10.7554/Elife.38986  0.608
2019 Huang YJ, Brock KP, Ishida Y, Swapna GVT, Inouye M, Marks DS, Sander C, Montelione GT. Combining Evolutionary Covariance and NMR Data for Protein Structure Determination. Methods in Enzymology. 614: 363-392. PMID 30611430 DOI: 10.1016/Bs.Mie.2018.11.004  0.614
2019 Xu J, Reznik E, Lee H, Gundem G, Jonsson P, Sarungbam J, Bialik A, Sanchez-Vega F, Creighton CJ, Hoekstra J, Zhang L, Sajjakulnukit P, Kremer D, Tolstyka Z, Casuscelli J, ... ... Sander C, et al. Author response: Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma Elife. DOI: 10.7554/Elife.38986.025  0.567
2019 Luna A, Wang H, Babur O, Sander C, Korkut A. Abstract 3820: Discovery of adaptive resistance pathways and anti-resistance combination therapies from phosphoproteomic data using graphical models Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3820  0.674
2019 Gao J, Mazor T, Abeshouse A, Bruijn Id, Gross B, Kalletla K, Kumari P, Kundra R, Li X, Lindsay J, Lisman A, Lukasse P, Madupuri R, Ochoa A, Plantalech O, ... ... Sander C, et al. Abstract 3209: The cBioPortal for Cancer Genomics Cancer Research. 80: 3209-3209. DOI: 10.1158/1538-7445.Am2020-3209  0.362
2018 Huang YJ, Brock KP, Sander C, Marks DS, Montelione GT. A Hybrid Approach for Protein Structure Determination Combining Sparse NMR with Evolutionary Coupling Sequence Data. Advances in Experimental Medicine and Biology. 1105: 153-169. PMID 30617828 DOI: 10.1007/978-981-13-2200-6_10  0.617
2018 Rajapakse VN, Luna A, Yamade M, Loman L, Varma S, Sunshine M, Iorio F, Sousa FG, Elloumi F, Aladjem MI, Thomas A, Sander C, Kohn KW, Benes CH, Garnett M, et al. CellMinerCDB for Integrative Cross-Database Genomics and Pharmacogenomics Analyses of Cancer Cell Lines. Iscience. PMID 30553813 DOI: 10.1016/J.Isci.2018.11.029  0.363
2018 Hopf TA, Green AG, Schubert B, Mersmann S, Schärfe CPI, Ingraham JB, Toth-Petroczy A, Brock K, Riesselman AJ, Palmedo P, Kang C, Sheridan R, Draizen EJ, Dallago C, Sander C, et al. The EVcouplings Python framework for coevolutionary sequence analysis. Bioinformatics (Oxford, England). PMID 30304492 DOI: 10.1093/Bioinformatics/Bty862  0.629
2018 Wedge DC, Gundem G, Mitchell T, Woodcock DJ, Martincorena I, Ghori M, Zamora J, Butler A, Whitaker H, Kote-Jarai Z, Alexandrov LB, Van Loo P, Massie CE, Dentro S, Warren AY, ... ... Sander C, et al. Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets. Nature Genetics. PMID 29662167 DOI: 10.1038/S41588-018-0086-Z  0.312
2018 Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, ... ... Sander C, et al. Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell. 173: 321-337.e10. PMID 29625050 DOI: 10.1016/J.Cell.2018.03.035  0.331
2018 Way GP, Sanchez-Vega F, La K, Armenia J, Chatila WK, Luna A, Sander C, Cherniack AD, Mina M, Ciriello G, Schultz N, Sanchez Y, Greene CS. Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. Cell Reports. 23: 172-180.e3. PMID 29617658 DOI: 10.1016/J.Celrep.2018.03.046  0.319
2018 Reznik E, Luna A, Aksoy BA, Liu EM, La K, Ostrovnaya I, Creighton CJ, Hakimi AA, Sander C. A Landscape of Metabolic Variation across Tumor Types. Cell Systems. PMID 29396322 DOI: 10.1016/J.Cels.2017.12.014  0.749
2018 Gao J, Mazor T, Ciftci E, Raman P, Lukasse P, Bahceci I, Sigaras A, Abeshouse A, Bruijn Id, Gross B, Kundra R, Lisman A, Ochoa A, Sheridan R, Su J, ... ... Sander C, et al. Abstract 923: The cBioPortal for Cancer Genomics: An intuitive open-source platform for exploration, analysis and visualization of cancer genomics data Cancer Research. 78: 923-923. DOI: 10.1158/1538-7445.Am2018-923  0.363
2018 Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La K, Dimitriadoy S, Liu DL, Kantheti HS, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, ... ... Sander C, et al. Abstract 3302: The molecular landscape of oncogenic signaling pathways in The Cancer Genome Atlas Cancer Research. 78: 3302-3302. DOI: 10.1158/1538-7445.Am2018-3302  0.357
2018 Luna A, Babur Ö, Yan G, Demir E, Sander C, Korkut A. Abstract 2838: Discovery of adaptive resistance pathways and anti-resistance combination therapies in cancer from phosphoproteomic data Cancer Research. 78: 2838-2838. DOI: 10.1158/1538-7445.Am2018-2838  0.623
2018 Wong JV, Luna A, Demir E, Rodchenkov I, Babur Ö, Sander C, Bader GD. Abstract 1284: How can you interpret gene lists from -omics experiments Cancer Research. 78: 1284-1284. DOI: 10.1158/1538-7445.Am2018-1284  0.358
2018 Brock K, Sander C, Marks D. Using evolutionary couplings to predict contacts and build structures Acta Crystallographica Section A. 74. DOI: 10.1107/S2053273318094536  0.556
2018 Sander C, Marks D. Solutions to the computational protein folding problem The Faseb Journal. 32. DOI: 10.1096/Fasebj.2018.32.1_Supplement.377.1  0.584
2017 Aksoy BA, Dancík V, Smith K, Mazerik JN, Ji Z, Gross B, Nikolova O, Jaber N, Califano A, Schreiber SL, Gerhard DS, Hermida LC, Jagu S, Sander C, Floratos A, et al. CTD2 Dashboard: a searchable web interface to connect validated results from the Cancer Target Discovery and Development Network. Database : the Journal of Biological Databases and Curation. 2017. PMID 29220450 DOI: 10.1093/Database/Bax054  0.668
2017 Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, ... ... Sander C, et al. Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Reports. 19: 2878-2880. PMID 28658632 DOI: 10.1016/J.Celrep.2017.06.008  0.601
2017 Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, ... ... Sander C, et al. Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Reports. 18: 2780-2794. PMID 28297679 DOI: 10.1016/J.Celrep.2017.02.033  0.609
2017 Gao J, Chang MT, Johnsen HC, Gao SP, Sylvester BE, Sumer SO, Zhang H, Solit DB, Taylor BS, Schultz N, Sander C. 3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets. Genome Medicine. 9: 4. PMID 28115009 DOI: 10.1186/S13073-016-0393-X  0.313
2017 Reznik E, Wang Q, La K, Schultz N, Sander C. Mitochondrial respiratory gene expression is suppressed in many cancers. Elife. 6. PMID 28099114 DOI: 10.7554/Elife.21592  0.603
2017 Hopf TA, Ingraham JB, Poelwijk FJ, Schärfe CP, Springer M, Sander C, Marks DS. Mutation effects predicted from sequence co-variation. Nature Biotechnology. PMID 28092658 DOI: 10.1038/Nbt.3769  0.702
2017 Wong JV, Luna A, Demir E, Rodchenkov I, Babur Ö, Sander C, Bader G. How can you interpret gene lists from -omics experiments? F1000research. 6. DOI: 10.7490/F1000Research.1115132.1  0.465
2017 Gao J, Ciftci E, Raman P, Lukasse P, Bahceci I, Abeshouse A, Chen H, Bruijn Id, Gross B, Heins Z, Kundra R, Lisman A, Ochoa A, Sheridan R, Sumer O, ... ... Sander C, et al. Abstract 2607: The cBioPortal for Cancer Genomics: an open source platform for accessing and interpreting complex cancer genomics data in the era of precision medicine Cancer Research. 77: 2607-2607. DOI: 10.1158/1538-7445.Am2017-2607  0.364
2017 Rajapakse VN, Luna A, Sander C, Reinhold WC, Pommier Y. Abstract 2586: CellMinerCDB: Enabling cross-database exploration of molecular pharmacology data and response determinant discovery in cancer cell lines Cancer Research. 77: 2586-2586. DOI: 10.1158/1538-7445.Am2017-2586  0.3
2016 Toth-Petroczy A, Palmedo P, Ingraham J, Hopf TA, Berger B, Sander C, Marks DS. Structured States of Disordered Proteins from Genomic Sequences. Cell. 167: 158-170.e12. PMID 27662088 DOI: 10.1016/J.Cell.2016.09.010  0.705
2016 Kusebauch U, Campbell DS, Deutsch EW, Chu CS, Spicer DA, Brusniak MY, Slagel J, Sun Z, Stevens J, Grimes B, Shteynberg D, Hoopmann MR, Blattmann P, Ratushny AV, Rinner O, ... ... Sander C, et al. Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome. Cell. PMID 27453469 DOI: 10.1016/J.Cell.2016.06.041  0.336
2016 Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, Krasnitz A, Sordella R, Sander C, Lowe SW, Powers S, Smith K, Aburi M, Iavarone A, Lasorella A, et al. Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Molecular Cancer Research : McR. PMID 27401613 DOI: 10.1158/1541-7786.Mcr-16-0090  0.326
2016 Weinreb C, Riesselman AJ, Ingraham JB, Gross T, Sander C, Marks DS. 3D RNA and Functional Interactions from Evolutionary Couplings. Cell. PMID 27087444 DOI: 10.1016/J.Cell.2016.03.030  0.701
2016 Chen F, Zhang Y, Şenbabaoğlu Y, Ciriello G, Yang L, Reznik E, Shuch B, Micevic G, De Velasco G, Shinbrot E, Noble MS, Lu Y, Covington KR, Xi L, Drummond JA, ... ... Sander C, et al. Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma. Cell Reports. PMID 26947078 DOI: 10.1016/J.Celrep.2016.02.024  0.611
2016 Şenbabaoğlu Y, Sümer SO, Sánchez-Vega F, Bemis D, Ciriello G, Schultz N, Sander C. A Multi-Method Approach for Proteomic Network Inference in 11 Human Cancers. Plos Computational Biology. 12: e1004765. PMID 26928298 DOI: 10.1371/Journal.Pcbi.1004765  0.375
2016 Reznik E, Miller ML, Şenbabaoğlu Y, Riaz N, Sarungbam J, Tickoo SK, Al-Ahmadie HA, Lee W, Seshan VE, Hakimi AA, Sander C. Mitochondrial DNA copy number variation across human cancers. Elife. 5. PMID 26901439 DOI: 10.7554/Elife.10769  0.603
2016 Hakimi AA, Reznik E, Lee CH, Creighton CJ, Brannon AR, Luna A, Aksoy BA, Liu EM, Shen R, Lee W, Chen Y, Stirdivant SM, Russo P, Chen YB, Tickoo SK, ... ... Sander C, et al. An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma. Cancer Cell. 29: 104-116. PMID 26766592 DOI: 10.1016/J.Ccell.2015.12.004  0.74
2016 Reznik E, Wang Q, La K, Schultz N, Sander C. Author response: Mitochondrial respiratory gene expression is suppressed in many cancers Elife. DOI: 10.7554/Elife.21592.018  0.566
2016 Gao J, Lindsay J, Watt S, Bahceci I, Lukasse P, Abeshouse A, Chen H, Bruijn Id, Gross B, Li D, Kundra R, Heins Z, Reis-Filho J, Sumer O, Sun Y, ... ... Sander C, et al. Abstract 5277: The cBioPortal for cancer genomics and its application in precision oncology Cancer Research. 76: 5277-5277. DOI: 10.1158/1538-7445.Am2016-5277  0.353
2016 Gao J, Chang MT, Sylvester BE, Johnsen HC, Gao SP, Sumer SO, Solit DB, Taylor BS, Schultz N, Sander C. Abstract 3606: Identification of oncogenic mutation hotspots via three-dimensional proximity Cancer Research. 76: 3606-3606. DOI: 10.1158/1538-7445.Am2016-3606  0.355
2016 Rosenzweig B, Reznik E, Shingarev R, Zabor EC, Stirdivant S, Sander C, Hsieh JJ, Jaimes EA, Russo P, Hakimi AA, Coleman JA. MP85-20 METABOLOMICS AND POST-NEPHRECTOMY RENAL FUNCTION PREDICTION Journal of Urology. 195. DOI: 10.1016/J.Juro.2016.02.2286  0.56
2015 Miller ML, Reznik E, Gauthier NP, Aksoy BA, Korkut A, Gao J, Ciriello G, Schultz N, Sander C. Pan-Cancer Analysis of Mutation Hotspots in Protein Domains. Cell Systems. 1: 197-209. PMID 27135912 DOI: 10.1016/J.Cels.2015.08.014  0.787
2015 Luna A, Babur Ö, Aksoy BA, Demir E, Sander C. PaxtoolsR: Pathway Analysis in R Using Pathway Commons. Bioinformatics (Oxford, England). PMID 26685306 DOI: 10.1093/Bioinformatics/Btv733  0.777
2015 Luna A, Rajapakse VN, Sousa FG, Gao J, Schultz N, Varma S, Reinhold W, Sander C, Pommier Y. rcellminer: Exploring Molecular Profiles and Drug Response of the NCI-60 Cell Lines in R. Bioinformatics (Oxford, England). PMID 26635141 DOI: 10.1093/Bioinformatics/Btv701  0.319
2015 Gauthier NP, Reznik E, Gao J, Sumer SO, Schultz N, Sander C, Miller ML. MutationAligner: a resource of recurrent mutation hotspots in protein domains in cancer. Nucleic Acids Research. PMID 26590264 DOI: 10.1093/Nar/Gkv1132  0.642
2015 Korkut A, Wang W, Demir E, Aksoy BA, Jing X, Molinelli EJ, Babur Ö, Bemis DL, Onur Sumer S, Solit DB, Pratilas CA, Sander C. Perturbation biology nominates upstream-downstream drug combinations in RAF inhibitor resistant melanoma cells. Elife. 4. PMID 26284497 DOI: 10.7554/Elife.04640  0.787
2015 Stein RR, Marks DS, Sander C. Inferring Pairwise Interactions from Biological Data Using Maximum-Entropy Probability Models. Plos Computational Biology. 11: e1004182. PMID 26225866 DOI: 10.1371/Journal.Pcbi.1004182  0.721
2015 Creixell P, Reimand J, Haider S, Wu G, Shibata T, Vazquez M, Mustonen V, Gonzalez-Perez A, Pearson J, Sander C, Raphael BJ, Marks DS, Ouellette BFF, Valencia A, Bader GD, et al. Pathway and network analysis of cancer genomes. Nature Methods. 12: 615-621. PMID 26125594 DOI: 10.1038/Nmeth.3440  0.782
2015 Tang Y, Huang YJ, Hopf TA, Sander C, Marks DS, Montelione GT. Protein structure determination by combining sparse NMR data with evolutionary couplings. Nature Methods. PMID 26121406 DOI: 10.1038/Nmeth.3455  0.712
2015 Ebhardt HA, Root A, Sander C, Aebersold R. Applications of targeted proteomics in systems biology and translational medicine. Proteomics. PMID 26097198 DOI: 10.1002/Pmic.201500004  0.312
2015 Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, ... ... Sander C, et al. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. 372: 2481-98. PMID 26061751 DOI: 10.1056/Nejmoa1402121  0.642
2015 Aad G, Abbott B, Abdallah J, Abdinov O, Aben R, Abolins M, AbouZeid OS, Abramowicz H, Abreu H, Abreu R, Abulaiti Y, Acharya BS, Adamczyk L, Adams DL, Adelman J, ... ... Sander C, et al. Combined Measurement of the Higgs Boson Mass in pp Collisions at sqrt[s]=7 and 8 TeV with the ATLAS and CMS Experiments. Physical Review Letters. 114: 191803. PMID 26024162 DOI: 10.1103/Physrevlett.114.191803  0.404
2015 Reznik E, Sander C. Extensive decoupling of metabolic genes in cancer. Plos Computational Biology. 11: e1004176. PMID 25961905 DOI: 10.1371/Journal.Pcbi.1004176  0.591
2015 Babur Ö, Gönen M, Aksoy BA, Schultz N, Ciriello G, Sander C, Demir E. Systematic identification of cancer driving signaling pathways based on mutual exclusivity of genomic alterations. Genome Biology. 16: 45. PMID 25887147 DOI: 10.1186/S13059-015-0612-6  0.796
2015 Hayat S, Sander C, Marks DS, Elofsson A. All-atom 3D structure prediction of transmembrane β-barrel proteins from sequences. Proceedings of the National Academy of Sciences of the United States of America. 112: 5413-8. PMID 25858953 DOI: 10.1073/Pnas.1419956112  0.715
2015 Sousa FG, Matuo R, Tang SW, Rajapakse VN, Luna A, Sander C, Varma S, Simon PH, Doroshow JH, Reinhold WC, Pommier Y. Alterations of DNA repair genes in the NCI-60 cell lines and their predictive value for anticancer drug activity. Dna Repair. 28: 107-15. PMID 25758781 DOI: 10.1016/J.Dnarep.2015.01.011  0.351
2015 Erson-Omay EZ, Ça?layan AO, Schultz N, Weinhold N, Omay SB, Özduman K, Köksal Y, Li J, Serin Harmanc? A, Clark V, Carrión-Grant G, Baranoski J, Ça?lar C, Barak T, Co?kun S, ... ... Sander C, et al. Somatic POLE mutations cause an ultramutated giant cell high-grade glioma subtype with better prognosis. Neuro-Oncology. PMID 25740784 DOI: 10.1093/Neuonc/Nov027  0.308
2015 Reznik E, Miller ML, Şenbabaoğlu Y, Riaz N, Sarungbam J, Tickoo SK, Al-Ahmadie HA, Lee W, Seshan VE, Hakimi AA, Sander C. Author response: Mitochondrial DNA copy number variation across human cancers Elife. DOI: 10.7554/Elife.10769.028  0.561
2015 Korkut A, Wang W, Demir E, Aksoy BA, Jing X, Molinelli EJ, Babur Ö, Bemis DL, Sumer SO, Solit DB, Pratilas CA, Sander C. Author response: Perturbation biology nominates upstream–downstream drug combinations in RAF inhibitor resistant melanoma cells Elife. DOI: 10.7554/Elife.04640.031  0.733
2015 Ciriello G, Gatza ML, Hoadley KA, Zhang H, Rhie SK, Bowlby R, Wilkerson MD, Kandoth C, McLellan M, Cherniack A, Laird PW, Sander C, King TA, Perou CM. Abstract S2-04: Comprehensive molecular characterization of invasive lobular breast tumors Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-S2-04  0.339
2015 Creixell P, Reimand J, Haider S, Wu G, Shibata T, Vazquez M, Mustonen V, Gonzalez-Perez A, Pearson J, Sander C, Raphael BJ, Marks DS, Ouellette BFF, Valencia A, Bader GD, et al. Pathway and network analysis of cancer genomes Nature Methods. 12: 615-621. DOI: 10.1038/nmeth.3440  0.69
2015 Miller ML, Reznik E, Gauthier NP, Aksoy BA, Korkut A, Gao J, Ciriello G, Schultz N, Sander C. Pan-Cancer Analysis of Mutation Hotspots in Protein Domains Cell Systems. 1: 197-209. DOI: 10.1016/S0959-8049(16)61060-2  0.723
2014 Kaushik P, Molinelli EJ, Miller ML, Wang W, Korkut A, Liu W, Ju Z, Lu Y, Mills G, Sander C. Spatial normalization of reverse phase protein array data. Plos One. 9: e97213. PMID 25501559 DOI: 10.1371/Journal.Pone.0097213  0.611
2014 Weinhold N, Jacobsen A, Schultz N, Sander C, Lee W. Genome-wide analysis of noncoding regulatory mutations in cancer. Nature Genetics. 46: 1160-5. PMID 25261935 DOI: 10.1038/Ng.3101  0.369
2014 Hopf TA, Schärfe CP, Rodrigues JP, Green AG, Kohlbacher O, Sander C, Bonvin AM, Marks DS. Sequence co-evolution gives 3D contacts and structures of protein complexes. Elife. 3. PMID 25255213 DOI: 10.7554/Elife.03430  0.729
2014 Michel M, Hayat S, Skwark MJ, Sander C, Marks DS, Elofsson A. PconsFold: improved contact predictions improve protein models. Bioinformatics (Oxford, England). 30: i482-8. PMID 25161237 DOI: 10.1093/Bioinformatics/Btu458  0.698
2014 Babur Ö, Dogrusoz U, Çakır M, Aksoy BA, Schultz N, Sander C, Demir E. Integrating biological pathways and genomic profiles with ChiBE 2. Bmc Genomics. 15: 642. PMID 25086704 DOI: 10.1186/1471-2164-15-642  0.675
2014 Yachdav G, Kloppmann E, Kajan L, Hecht M, Goldberg T, Hamp T, Hönigschmid P, Schafferhans A, Roos M, Bernhofer M, Richter L, Ashkenazy H, Punta M, Schlessinger A, Bromberg Y, ... ... Sander C, et al. PredictProtein--an open resource for online prediction of protein structural and functional features. Nucleic Acids Research. 42: W337-43. PMID 24799431 DOI: 10.1093/Nar/Gku366  0.809
2014 Aksoy BA, Demir E, Babur Ö, Wang W, Jing X, Schultz N, Sander C. Prediction of individualized therapeutic vulnerabilities in cancer from genomic profiles. Bioinformatics (Oxford, England). 30: 2051-9. PMID 24665131 DOI: 10.1093/Bioinformatics/Btu164  0.685
2014 Gao J, Ciriello G, Sander C, Schultz N. Collection, integration and analysis of cancer genomic profiles: from data to insight. Current Opinion in Genetics & Development. 24: 92-8. PMID 24584084 DOI: 10.1016/J.Gde.2013.12.003  0.373
2014 Babur Ö, Aksoy BA, Rodchenkov I, Sümer SO, Sander C, Demir E. Pattern search in BioPAX models. Bioinformatics (Oxford, England). 30: 139-40. PMID 24045775 DOI: 10.1093/Bioinformatics/Btt539  0.662
2014 Hopf TA, Schärfe CPI, Rodrigues JPGLM, Green AG, Kohlbacher O, Sander C, Bonvin AMJJ, Marks DS. Author response: Sequence co-evolution gives 3D contacts and structures of protein complexes Elife. DOI: 10.7554/Elife.03430.032  0.59
2014 Gao J, Aksoy BA, Gross B, Dresdner G, Sun Y, Sumer SO, Sander C, Schultz N. Abstract 4271: The cBioPortal for Cancer Genomics as a clinical decision support tool Cancer Research. 74: 4271-4271. DOI: 10.1158/1538-7445.Am2014-4271  0.681
2013 Molinelli EJ, Korkut A, Wang W, Miller ML, Gauthier NP, Jing X, Kaushik P, He Q, Mills G, Solit DB, Pratilas CA, Weigt M, Braunstein A, Pagnani A, Zecchina R, ... Sander C, et al. Perturbation biology: inferring signaling networks in cellular systems. Plos Computational Biology. 9: e1003290. PMID 24367245 DOI: 10.1371/Journal.Pcbi.1003290  0.638
2013 Akrami R, Jacobsen A, Hoell J, Schultz N, Sander C, Larsson E. Comprehensive analysis of long non-coding RNAs in ovarian cancer reveals global patterns and targeted DNA amplification. Plos One. 8: e80306. PMID 24265805 DOI: 10.1371/Journal.Pone.0080306  0.352
2013 Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, ... ... Sander C, et al. The somatic genomic landscape of glioblastoma. Cell. 155: 462-77. PMID 24120142 DOI: 10.1016/J.Cell.2013.09.034  0.371
2013 Ciriello G, Sinha R, Hoadley KA, Jacobsen AS, Reva B, Perou CM, Sander C, Schultz N. The molecular diversity of Luminal A breast tumors. Breast Cancer Research and Treatment. 141: 409-20. PMID 24096568 DOI: 10.1007/S10549-013-2699-3  0.322
2013 Jacobsen A, Silber J, Harinath G, Huse JT, Schultz N, Sander C. Analysis of microRNA-target interactions across diverse cancer types. Nature Structural & Molecular Biology. 20: 1325-32. PMID 24096364 DOI: 10.1038/Nsmb.2678  0.311
2013 Ciriello G, Miller ML, Aksoy BA, Senbabaoglu Y, Schultz N, Sander C. Emerging landscape of oncogenic signatures across human cancers. Nature Genetics. 45: 1127-33. PMID 24071851 DOI: 10.1038/Ng.2762  0.68
2013 Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM. The Cancer Genome Atlas Pan-Cancer analysis project. Nature Genetics. 45: 1113-20. PMID 24071849 DOI: 10.1038/Ng.2764  0.347
2013 Demir E, Babur O, Rodchenkov I, Aksoy BA, Fukuda KI, Gross B, Sümer OS, Bader GD, Sander C. Using biological pathway data with paxtools. Plos Computational Biology. 9: e1003194. PMID 24068901 DOI: 10.1371/Journal.Pcbi.1003194  0.784
2013 Miller ML, Molinelli EJ, Nair JS, Sheikh T, Samy R, Jing X, He Q, Korkut A, Crago AM, Singer S, Schwartz GK, Sander C. Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets. Science Signaling. 6: ra85. PMID 24065146 DOI: 10.1126/Scisignal.2004014  0.62
2013 Rodchenkov I, Demir E, Sander C, Bader GD. The BioPAX Validator. Bioinformatics (Oxford, England). 29: 2659-60. PMID 23918249 DOI: 10.1093/Bioinformatics/Btt452  0.492
2013 Gonzalez-Perez A, Mustonen V, Reva B, Ritchie GR, Creixell P, Karchin R, Vazquez M, Fink JL, Kassahn KS, Pearson JV, Bader GD, Boutros PC, Muthuswamy L, Ouellette BF, Reimand J, ... ... Sander C, et al. Computational approaches to identify functional genetic variants in cancer genomes. Nature Methods. 10: 723-9. PMID 23900255 DOI: 10.1038/Nmeth.2562  0.626
2013 Iyer G, Al-Ahmadie H, Schultz N, Hanrahan AJ, Ostrovnaya I, Balar AV, Kim PH, Lin O, Weinhold N, Sander C, Zabor EC, Janakiraman M, Garcia-Grossman IR, Heguy A, Viale A, et al. Prevalence and co-occurrence of actionable genomic alterations in high-grade bladder cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 3133-40. PMID 23897969 DOI: 10.1200/Jco.2012.46.5740  0.367
2013 Aksoy BA, Gao J, Dresdner G, Wang W, Root A, Jing X, Cerami E, Sander C. PiHelper: an open source framework for drug-target and antibody-target data. Bioinformatics (Oxford, England). 29: 2071-2. PMID 23766416 DOI: 10.1093/Bioinformatics/Btt345  0.666
2013 Ho AS, Kannan K, Roy DM, Morris LG, Ganly I, Katabi N, Ramaswami D, Walsh LA, Eng S, Huse JT, Zhang J, Dolgalev I, Huberman K, Heguy A, Viale A, ... ... Sander C, et al. The mutational landscape of adenoid cystic carcinoma. Nature Genetics. 45: 791-8. PMID 23685749 DOI: 10.1038/Ng.2643  0.311
2013 Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, Sun Y, Jacobsen A, Sinha R, Larsson E, Cerami E, Sander C, Schultz N. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Science Signaling. 6: pl1. PMID 23550210 DOI: 10.1126/scisignal.2004088  0.676
2013 Ciriello G, Cerami E, Aksoy BA, Sander C, Schultz N. Using MEMo to discover mutual exclusivity modules in cancer. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit 8.17. PMID 23504936 DOI: 10.1002/0471250953.Bi0817S41  0.701
2013 Mo Q, Wang S, Seshan VE, Olshen AB, Schultz N, Sander C, Powers RS, Ladanyi M, Shen R. Pattern discovery and cancer gene identification in integrated cancer genomic data. Proceedings of the National Academy of Sciences of the United States of America. 110: 4245-50. PMID 23431203 DOI: 10.1073/Pnas.1208949110  0.355
2013 John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS. Potential miRNA Target Sites in the 3′ UTRs of Selected Genes Plos Biology. DOI: 10.1371/Journal.Pbio.0020363.G004  0.539
2013 Schultz N, Sander C. Abstract SY12-02: Computational cancer genomics: Biological discovery and translation. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy12-02  0.357
2013 Giovanni C, Perou CM, Sander C, Schultz N. Abstract 822: The molecular diversity of Luminal A breast cancer. Cancer Research. 73: 822-822. DOI: 10.1158/1538-7445.Am2013-822  0.338
2013 Korkut A, Wang W, Molinelli E, Miller M, Kaushik P, Aksoy A, Sander C. Abstract 5227: Quantitative network models of signaling and drug response in melanoma. Cancer Research. 73: 5227-5227. DOI: 10.1158/1538-7445.Am2013-5227  0.621
2013 Gao J, Sumer SO, Dresdner G, Aksoy BA, Sander C, Schultz N. Abstract 5140: Individual patient cancer profiles in the cBio Cancer Genomic Portal. Cancer Research. 73: 5140-5140. DOI: 10.1158/1538-7445.Am2013-5140  0.693
2013 Voss MH, Hakimi AA, Pham CG, Brannon AR, Chen Y, Cunha LF, Akin O, Liu H, Takeda S, Scott SN, Socci ND, Viale A, Schultz N, Sander C, Reuter VE, et al. Abstract 3515: Pathway convergent evolution underscores treatment response to MTOR inhibitors in kidney cancers. Cancer Research. 73: 3515-3515. DOI: 10.1158/1538-7445.Am2013-3515  0.352
2013 Korkut A, Wang W, Molinelli E, Miller M, Kaushik P, Aksoy A, Jing X, Gauthier N, Sander C. Abstract A24: Network models of signaling and drug response in melanoma. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A24  0.339
2012 Marks DS, Hopf TA, Sander C. Protein structure prediction from sequence variation. Nature Biotechnology. 30: 1072-80. PMID 23138306 DOI: 10.1038/Nbt.2419  0.638
2012 Iyer G, Hanrahan AJ, Milowsky MI, Al-Ahmadie H, Scott SN, Janakiraman M, Pirun M, Sander C, Socci ND, Ostrovnaya I, Viale A, Heguy A, Peng L, Chan TA, Bochner B, et al. Genome sequencing identifies a basis for everolimus sensitivity. Science (New York, N.Y.). 338: 221. PMID 22923433 DOI: 10.1126/Science.1226344  0.357
2012 Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, Jacobsen A, Byrne CJ, Heuer ML, Larsson E, Antipin Y, Reva B, Goldberg AP, Sander C, Schultz N. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discovery. 2: 401-4. PMID 22588877 DOI: 10.1158/2159-8290.Cd-12-0095  0.686
2012 Hopf TA, Colwell LJ, Sheridan R, Rost B, Sander C, Marks DS. Three-dimensional structures of membrane proteins from genomic sequencing. Cell. 149: 1607-21. PMID 22579045 DOI: 10.1016/J.Cell.2012.04.012  0.77
2012 Shen R, Mo Q, Schultz N, Seshan VE, Olshen AB, Huse J, Ladanyi M, Sander C. Integrative subtype discovery in glioblastoma using iCluster. Plos One. 7: e35236. PMID 22539962 DOI: 10.1371/Journal.Pone.0035236  0.365
2012 Creighton CJ, Hernandez-Herrera A, Jacobsen A, Levine DA, Mankoo P, Schultz N, Du Y, Zhang Y, Larsson E, Sheridan R, Xiao W, Spellman PT, Getz G, Wheeler DA, Perou CM, ... ... Sander C, et al. Integrated analyses of microRNAs demonstrate their widespread influence on gene expression in high-grade serous ovarian carcinoma. Plos One. 7: e34546. PMID 22479643 DOI: 10.1371/Journal.Pone.0034546  0.3
2012 Hanrahan AJ, Schultz N, Westfal ML, Sakr RA, Giri DD, Scarperi S, Janakiraman M, Janikariman M, Olvera N, Stevens EV, She QB, Aghajanian C, King TA, Stanchina Ed, Spriggs DR, ... ... Sander C, et al. Genomic complexity and AKT dependence in serous ovarian cancer. Cancer Discovery. 2: 56-67. PMID 22328975 DOI: 10.1158/2159-8290.Cd-11-0170  0.312
2012 Ciriello G, Cerami E, Sander C, Schultz N. Mutual exclusivity analysis identifies oncogenic network modules. Genome Research. 22: 398-406. PMID 21908773 DOI: 10.1101/Gr.125567.111  0.378
2012 Iyer G, Milowsky MI, Al-Ahmadie H, Hanrahan A, Janakiraman M, Heguy A, Viale A, Socci ND, Sander C, Bochner B, Bajorin DF, Berger MF, Taylor BS, Solit DB. Defining the genetic basis of everolimus sensitivity in metastatic bladder cancer (MBC) by whole-genome sequencing (WGS). Journal of Clinical Oncology. 30: 4527-4527. DOI: 10.1200/Jco.2012.30.15_Suppl.4527  0.319
2012 Holm L, Sander C. Locating domains in three‐dimensional structures International Tables For Crystallography. DOI: 10.1107/97809553602060000891  0.337
2012 Demir E, Cary MP, Paley S, Fukuda K, Lemer C, Vastrik I, Wu G, D'Eustachio P, Schaefer C, Luciano J, Schacherer F, Martinez-Flores I, Hu Z, Jimenez-Jacinto V, Joshi-Tope G, ... ... Sander C, et al. The BioPAX community standard for pathway data sharing (Nature Biotechnology (2010) 28, (935-942)) Nature Biotechnology. 30: 365. DOI: 10.1038/Nbt0412-365C  0.471
2012 Morcos F, Pagnini A, Lunt B, Bertolino A, Marks D, Sander C, Zecchina R, Onuchic JN, Hwa T, Weigt M. Estimation of Residue-Residue Coevolution using Direct Coupling Analysis Identifies Many Native Contacts Across a Large Number of Domain Families Biophysical Journal. 102: 250a. DOI: 10.1016/J.Bpj.2011.11.1378  0.614
2011 Taylor BS, DeCarolis PL, Angeles CV, Brenet F, Schultz N, Antonescu CR, Scandura JM, Sander C, Viale AJ, Socci ND, Singer S. Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas. Cancer Discovery. 1: 587-97. PMID 22328974 DOI: 10.1158/2159-8290.Cd-11-0181  0.329
2011 Marks DS, Colwell LJ, Sheridan R, Hopf TA, Pagnani A, Zecchina R, Sander C. Protein 3D structure computed from evolutionary sequence variation. Plos One. 6: e28766. PMID 22163331 DOI: 10.1371/Journal.Pone.0028766  0.738
2011 Morcos F, Pagnani A, Lunt B, Bertolino A, Marks DS, Sander C, Zecchina R, Onuchic JN, Hwa T, Weigt M. Direct-coupling analysis of residue coevolution captures native contacts across many protein families. Proceedings of the National Academy of Sciences of the United States of America. 108: E1293-301. PMID 22106262 DOI: 10.1073/Pnas.1111471108  0.732
2011 Mankoo PK, Shen R, Schultz N, Levine DA, Sander C. Time to recurrence and survival in serous ovarian tumors predicted from integrated genomic profiles. Plos One. 6: e24709. PMID 22073136 DOI: 10.1371/Journal.Pone.0024709  0.346
2011 Reva B, Antipin Y, Sander C. Predicting the functional impact of protein mutations: application to cancer genomics. Nucleic Acids Research. 39: e118. PMID 21727090 DOI: 10.1093/Nar/Gkr407  0.361
2011 Bott M, Brevet M, Taylor BS, Shimizu S, Ito T, Wang L, Creaney J, Lake RA, Zakowski MF, Reva B, Sander C, Delsite R, Powell S, Zhou Q, Shen R, et al. The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma. Nature Genetics. 43: 668-72. PMID 21642991 DOI: 10.1038/Ng.855  0.307
2011 Jörnsten R, Abenius T, Kling T, Schmidt L, Johansson E, Nordling TE, Nordlander B, Sander C, Gennemark P, Funa K, Nilsson B, Lindahl L, Nelander S. Network modeling of the transcriptional effects of copy number aberrations in glioblastoma. Molecular Systems Biology. 7: 486. PMID 21525872 DOI: 10.1038/Msb.2011.17  0.373
2011 Schultz N, Marenstein DR, De Angelis DA, Wang WQ, Nelander S, Jacobsen A, Marks DS, Massagué J, Sander C. Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2. Silence. 2: 3. PMID 21401928 DOI: 10.1186/1758-907X-2-3  0.696
2011 Joosten RP, te Beek TA, Krieger E, Hekkelman ML, Hooft RW, Schneider R, Sander C, Vriend G. A series of PDB related databases for everyday needs. Nucleic Acids Research. 39: D411-9. PMID 21071423 DOI: 10.1093/Nar/Gkq1105  0.658
2011 Cerami EG, Gross BE, Demir E, Rodchenkov I, Babur O, Anwar N, Schultz N, Bader GD, Sander C. Pathway Commons, a web resource for biological pathway data. Nucleic Acids Research. 39: D685-90. PMID 21071392 DOI: 10.1093/Nar/Gkq1039  0.747
2010 Larsson E, Sander C, Marks D. mRNA turnover rate limits siRNA and microRNA efficacy. Molecular Systems Biology. 6: 433. PMID 21081925 DOI: 10.1038/Msb.2010.89  0.685
2010 Demir E, Cary MP, Paley S, Fukuda K, Lemer C, Vastrik I, Wu G, D'Eustachio P, Schaefer C, Luciano J, Schacherer F, Martinez-Flores I, Hu Z, Jimenez-Jacinto V, Joshi-Tope G, ... ... Sander C, et al. The BioPAX community standard for pathway data sharing. Nature Biotechnology. 28: 935-42. PMID 20829833 DOI: 10.1038/Nbt.1666  0.748
2010 Betel D, Koppal A, Agius P, Sander C, Leslie C. Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biology. 11: R90. PMID 20799968 DOI: 10.1186/Gb-2010-11-8-R90  0.329
2010 Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, Shah K, Socci ND, Weir BA, Ho A, Chiang DY, Reva B, Mermel CH, Getz G, Antipin Y, ... ... Sander C, et al. Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nature Genetics. 42: 715-21. PMID 20601955 DOI: 10.1038/Ng.619  0.348
2010 Babur O, Demir E, Gönen M, Sander C, Dogrusoz U. Discovering modulators of gene expression. Nucleic Acids Research. 38: 5648-56. PMID 20466809 DOI: 10.1093/Nar/Gkq287  0.695
2010 Arvey A, Larsson E, Sander C, Leslie CS, Marks DS. Target mRNA abundance dilutes microRNA and siRNA activity. Molecular Systems Biology. 6: 363. PMID 20404830 DOI: 10.1038/Msb.2010.24  0.682
2010 Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, ... ... Sander C, ... ... Sander C, et al. International network of cancer genome projects. Nature. 464: 993-8. PMID 20393554 DOI: 10.1038/Nature08987  0.614
2010 Cerami E, Demir E, Schultz N, Taylor BS, Sander C. Automated network analysis identifies core pathways in glioblastoma. Plos One. 5: e8918. PMID 20169195 DOI: 10.1371/Journal.Pone.0008918  0.39
2010 Kandasamy K, Mohan SS, Raju R, Keerthikumar S, Kumar GS, Venugopal AK, Telikicherla D, Navarro JD, Mathivanan S, Pecquet C, Gollapudi SK, Tattikota SG, Mohan S, Padhukasahasram H, Subbannayya Y, ... ... Sander C, et al. NetPath: a public resource of curated signal transduction pathways. Genome Biology. 11: R3. PMID 20067622 DOI: 10.1186/Gb-2010-11-1-R3  0.491
2010 Babur O, Dogrusoz U, Demir E, Sander C. ChiBE: interactive visualization and manipulation of BioPAX pathway models. Bioinformatics (Oxford, England). 26: 429-31. PMID 20007251 DOI: 10.1093/Bioinformatics/Btp665  0.695
2010 Demir E, Cary MP, Paley S, Fukuda K, Lemer C, Vastrik I, Wu G, D'Eustachio P, Schaefer C, Luciano J, Schacherer F, Martinez-Flores I, Hu Z, Jimenez-Jacinto V, Joshi-Tope G, ... ... Sander C, et al. Erratum: Corrigendum: The BioPAX community standard for pathway data sharing Nature Biotechnology. 28: 1308-1308. DOI: 10.1038/Nbt1210-1308C  0.468
2010 Larsson E, Sander C, Marks D. Erratum: mRNA Turnover Rate Limits siRNA and microRNA Efficacy Molecular Systems Biology. DOI: 10.1038/Msb.2010.113  0.51
2010 Zhao X, Schultz N, Taylor BS, Cerami E, Baumbusch LO, Haakensen VD, Lingjærde OC, Kristensen VN, Sander C, Børresen-Dale AL. 823 Pathway signatures in breast cancer progression − a genome-scale study based on integration of biology networks, DNA copy number, gene expression and mutations Ejc Supplements. 8: 207-208. DOI: 10.1016/S1359-6349(10)71619-0  0.321
2009 Chitale D, Gong Y, Taylor BS, Broderick S, Brennan C, Somwar R, Golas B, Wang L, Motoi N, Szoke J, Reinersman JM, Major J, Sander C, Seshan VE, Zakowski MF, et al. An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors. Oncogene. 28: 2773-83. PMID 19525976 DOI: 10.1038/Onc.2009.135  0.313
2009 Veeriah S, Brennan C, Meng S, Singh B, Fagin JA, Solit DB, Paty PB, Rohle D, Vivanco I, Chmielecki J, Pao W, Ladanyi M, Gerald WL, Liau L, Cloughesy TC, ... ... Sander C, et al. The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers. Proceedings of the National Academy of Sciences of the United States of America. 106: 9435-40. PMID 19478061 DOI: 10.1073/Pnas.0900571106  0.31
2009 Khan AA, Betel D, Miller ML, Sander C, Leslie CS, Marks DS. Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. Nature Biotechnology. 27: 549-55. PMID 19465925 DOI: 10.1038/Nbt.1543  0.677
2009 Aebersold R, Auffray C, Baney E, Barillot E, Brazma A, Brett C, Brunak S, Butte A, Califano A, Celis J, Cufer T, Ferrell J, Galas D, Gallahan D, Gatenby R, ... ... Sander C, et al. Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008). Molecular Oncology. 3: 9-17. PMID 19383362 DOI: 10.1016/J.Molonc.2008.11.003  0.334
2009 Khan AA, Betel D, Miller ML, Sander C, Leslie CS, Marks DS. Corrigendum: Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs Nature Biotechnology. 27: 671-671. DOI: 10.1038/Nbt0709-671A  0.524
2009 Levitt M, Sander C, Stern PS. The normal modes of a protein: Native bovine pancreatic trypsin inhibitor International Journal of Quantum Chemistry. 24: 181-199. DOI: 10.1002/Qua.560240721  0.431
2008 Leitner F, Krallinger M, Rodriguez-Penagos C, Hakenberg J, Plake C, Kuo CJ, Hsu CN, Tsai RT, Hung HC, Lau WW, Johnson CA, Saetre R, Yoshida K, Chen YH, Kim S, ... ... Sander C, et al. Introducing meta-services for biomedical information extraction. Genome Biology. 9: S6. PMID 18834497 DOI: 10.1186/Gb-2008-9-S2-S6  0.484
2008 Tonikian R, Zhang Y, Sazinsky SL, Currell B, Yeh JH, Reva B, Held HA, Appleton BA, Evangelista M, Wu Y, Xin X, Chan AC, Seshagiri S, Lasky LA, Sander C, et al. A specificity map for the PDZ domain family. Plos Biology. 6: e239. PMID 18828675 DOI: 10.1371/Journal.Pbio.0060239  0.522
2008 Taylor BS, Barretina J, Socci ND, Decarolis P, Ladanyi M, Meyerson M, Singer S, Sander C. Functional copy-number alterations in cancer. Plos One. 3: e3179. PMID 18784837 DOI: 10.1371/Journal.Pone.0003179  0.334
2008 Nelander S, Wang W, Nilsson B, She Q, Pratilas C, Rosen N, Gennemark P, Sander C. Models from experiments: combinatorial drug perturbations of cancer cells Molecular Systems Biology. 4: 216-216. PMID 18766176 DOI: 10.1038/Msb.2008.53  0.337
2008 Aragues R, Sander C, Oliva B. Predicting cancer involvement of genes from heterogeneous data. Bmc Bioinformatics. 9: 172-172. PMID 18371197 DOI: 10.1186/1471-2105-9-172  0.34
2008 Rost B, Casadio R, Fariselli P, Sander C. Transmembrane helices predicted at 95% accuracy Protein Science. 4: 521-533. PMID 7795533 DOI: 10.1002/Pro.5560040318  0.54
2007 Betel D, Wilson M, Gabow AP, Marks DS, Sander C. The microRNA.org resource: targets and expression Nucleic Acids Research. 36: 149-153. PMID 18158296 DOI: 10.1093/Nar/Gkm995  0.705
2007 Reva B, Antipin Y, Sander C. Determinants of protein function revealed by combinatorial entropy optimization Genome Biology. 8: 1-15. PMID 17976239 DOI: 10.1186/Gb-2007-8-11-R232  0.346
2007 Cline MS, Smoot M, Cerami E, Kuchinsky A, Landys N, Workman C, Christmas R, Avila-Campilo I, Creech M, Gross B, Hanspers K, Isserlin R, Kelley R, Killcoyne S, Lotia S, ... ... Sander C, et al. Integration of biological networks and gene expression data using Cytoscape. Nature Protocols. 2: 2366-82. PMID 17947979 DOI: 10.1038/Nprot.2007.324  0.521
2007 Singer S, Socci ND, Ambrosini G, Sambol E, Decarolis P, Wu Y, O'Connor R, Maki R, Viale A, Sander C, Schwartz GK, Antonescu CR. Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma. Cancer Research. 67: 6626-36. PMID 17638873 DOI: 10.1158/0008-5472.Can-07-0584  0.306
2007 Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, ... ... Sander C, et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell. 129: 1401-14. PMID 17604727 DOI: 10.1016/J.Cell.2007.04.040  0.314
2007 Mathew JP, Taylor BS, Bader GD, Pyarajan S, Antoniotti M, Chinnaiyan AM, Sander C, Burakoff SJ, Mishra B. From bytes to bedside: data integration and computational biology for translational cancer research. Plos Computational Biology. 3: e12. PMID 17319736 DOI: 10.1371/Journal.Pcbi.0030012  0.533
2007 Higgins ME, Claremont M, Major JE, Sander C, Lash AE. CancerGenes: a gene selection resource for cancer genome projects. Nucleic Acids Research. 35: D721-6. PMID 17088289 DOI: 10.1093/Nar/Gkl811  0.368
2006 Cerami EG, Bader GD, Gross BE, Sander C. cPath: open source software for collecting, storing, and querying biological pathways. Bmc Bioinformatics. 7: 497. PMID 17101041 DOI: 10.1186/1471-2105-7-497  0.531
2006 John B, Sander C, Marks DS. Prediction of human microRNA targets. Methods of Molecular Biology. 342: 101-113. PMID 16957370 DOI: 10.1385/1-59745-123-1:101  0.686
2006 Aravin A, Gaidatzis D, Pfeffer S, Lagos-Quintana M, Landgraf P, Iovino N, Morris P, Brownstein MJ, Kuramochi-Miyagawa S, Nakano T, Chien M, Russo JJ, Ju J, Sheridan R, Sander C, et al. A novel class of small RNAs bind to MILI protein in mouse testes. Nature. 442: 203-7. PMID 16751777 DOI: 10.1038/Nature04916  0.308
2006 Bader GD, Cary MP, Sander C. Pathguide: a pathway resource list. Nucleic Acids Research. 34: D504-6. PMID 16381921 DOI: 10.1093/Nar/Gkj126  0.553
2006 Orengo CA, Thornton JM, Holm L, Sander C. Protein folds and motifs: representation, comparison and classification International Tables For Crystallography. DOI: 10.1107/97809553602060000714  0.355
2005 Betel D, Sheridan RP, Marks DS, Sander C. Computational analysis of mouse piRNA sequence and biogenesis. Plos Computational Biology. 3. PMID 17997596 DOI: 10.1371/Journal.Pcbi.0030222  0.694
2005 Monticelli S, Ansel KM, Xiao C, Socci ND, Krichevsky AM, Thai TH, Rajewsky N, Marks DS, Sander C, Rajewsky K, Rao A, Kosik KS. MicroRNA profiling of the murine hematopoietic system. Genome Biology. 6: R71. PMID 16086853 DOI: 10.1186/Gb-2005-6-8-R71  0.672
2005 Leaman D, Chen PY, Fak J, Yalcin A, Pearce M, Unnerstall U, Marks DS, Sander C, Tuschl T, Gaul U. Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development. Cell. 121: 1097-108. PMID 15989958 DOI: 10.1016/J.Cell.2005.04.016  0.679
2005 Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T. The developmental miRNA profiles of zebrafish as determined by small RNA cloning. Genes & Development. 19: 1288-93. PMID 15937218 DOI: 10.1101/Gad.1310605  0.672
2005 Cary MP, Bader GD, Sander C. Pathway information for systems biology. Febs Letters. 579: 1815-20. PMID 15763557 DOI: 10.1016/J.Febslet.2005.02.005  0.498
2005 John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS. Correction: Human MicroRNA Targets Plos Biology. 3: e264. DOI: 10.1371/Journal.Pbio.0030264  0.565
2004 Chang J, Nicolas E, Marks D, Sander C, Lerro A, Buendia MA, Xu C, Mason WS, Moloshok T, Bort R, Zaret KS, Taylor JM. miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. Rna Biology. 1: 106-13. PMID 17179747 DOI: 10.4161/Rna.1.2.1066  0.669
2004 John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS. Human MicroRNA targets. Plos Biology. 2: e363. PMID 15502875 DOI: 10.1371/Journal.Pbio.0020363  0.696
2004 Pfeffer S, Zavolan M, Grässer FA, Chien M, Russo JJ, Ju J, John B, Enright AJ, Marks D, Sander C, Tuschl T. Identification of virus-encoded microRNAs. Science (New York, N.Y.). 304: 734-6. PMID 15118162 DOI: 10.1126/Science.1096781  0.668
2004 Tong AH, Lesage G, Bader GD, Ding H, Xu H, Xin X, Young J, Berriz GF, Brost RL, Chang M, Chen Y, Cheng X, Chua G, Friesen H, Goldberg DS, ... ... Sander C, et al. Global mapping of the yeast genetic interaction network. Science (New York, N.Y.). 303: 808-13. PMID 14764870 DOI: 10.1126/Science.1091317  0.63
2004 Hermjakob H, Montecchi-Palazzi L, Bader G, Wojcik J, Salwinski L, Ceol A, Moore S, Orchard S, Sarkans U, von Mering C, Roechert B, Poux S, Jung E, Mersch H, Kersey P, ... ... Sander C, et al. The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data. Nature Biotechnology. 22: 177-83. PMID 14755292 DOI: 10.1038/Nbt926  0.736
2003 Enright AJ, John B, Gaul U, Tuschl T, Sander C, Marks DS. MicroRNA targets in Drosophila. Genome Biology. 5: R1. PMID 14709173 DOI: 10.1186/Gb-2003-5-1-R1  0.578
2003 Berriz GF, King OD, Bryant B, Sander C, Roth FP. Characterizing gene sets with FuncAssociate. Bioinformatics (Oxford, England). 19: 2502-4. PMID 14668247 DOI: 10.1093/Bioinformatics/Btg363  0.536
2003 Iliopoulos I, Tsoka S, Andrade MA, Enright AJ, Carroll M, Poullet P, Promponas V, Liakopoulos T, Palaios G, Pasquier C, Hamodrakas S, Tamames J, Yagnik AT, Tramontano A, Devos D, ... ... Sander C, et al. Evaluation of annotation strategies using an entire genome sequence. Bioinformatics (Oxford, England). 19: 717-26. PMID 12691983 DOI: 10.1093/Bioinformatics/Btg077  0.51
2001 Vitkup D, Melamud E, Moult J, Sander C. Completeness in structural genomics Nature Structural Biology. 8: 559-565. PMID 11373627 DOI: 10.1038/88640  0.343
2001 Iliopoulos I, Tsoka S, Andrade MA, Janssen P, Audit B, Tramontano A, Valencia A, Leroy C, Sander C, Ouzounis CA. Genome sequences and great expectations. Genome Biology. 2: INTERACTIONS0001. PMID 11178275 DOI: 10.1186/Gb-2000-2-1-Interactions0001  0.53
2001 Rost B, Sander C. Third generation prediction of secondary structures. Methods in Molecular Biology (Clifton, N.J.). 143: 71-95. PMID 11084903 DOI: 10.1385/1-59259-368-2:71  0.493
2000 Promponas VJ, Enright AJ, Tsoka S, Kreil DP, Leroy C, Hamodrakas S, Sander C, Ouzounis CA. CAST: an iterative algorithm for the complexity analysis of sequence tracts. Complexity analysis of sequence tracts. Bioinformatics (Oxford, England). 16: 915-22. PMID 11120681 DOI: 10.1093/Bioinformatics/16.10.915  0.308
2000 Hoersch S, Leroy C, Brown NP, Andrade MA, Sander C. The GeneQuiz Web server: Protein functional analysis through the Web Trends in Biochemical Sciences. 25: 33-35. PMID 10637611 DOI: 10.1016/S0968-0004(99)01510-8  0.351
1999 Andrade MA, Ouzounis C, Sander C, Tamames J, Valencia A. Functional classes in the three domains of life Journal of Molecular Evolution. 49: 551-557. PMID 10552036 DOI: 10.1007/Pl00006576  0.475
1999 Andrade MA, Brown NP, Leroy C, Hoersch S, De Daruvar A, Reich C, Franchini A, Tamames J, Valencia A, Ouzounis C, Sander C. Automated genome sequence analysis and annotation Bioinformatics. 15: 391-412. PMID 10366660 DOI: 10.1093/Bioinformatics/15.5.391  0.545
1999 Holm L, Sander C. Protein folds and families: sequence and structure alignments Nucleic Acids Research. 27: 244-247. PMID 9847191 DOI: 10.1093/Nar/27.1.244  0.38
1998 Holm L, Sander C. Dictionary of recurrent domains in protein structures. Proteins. 33: 88-96. PMID 9741847 DOI: 10.1002/(Sici)1097-0134(19981001)33:1<88::Aid-Prot8>3.0.Co;2-H  0.37
1998 Tamames J, Ouzounis C, Casari G, Sander C, Valencia A. EUCLID : Automatic classification of proteins in functional classes by their database annotations Bioinformatics. 14: 542-543. PMID 9694995 DOI: 10.1093/Bioinformatics/14.6.542  0.497
1998 Holm L, Sander C. Removing near-neighbour redundancy from large protein sequence collections. Bioinformatics. 14: 423-429. PMID 9682055 DOI: 10.1093/Bioinformatics/14.5.423  0.341
1998 Brown NP, Leroy C, Sander C. MView: A web-compatible database search or multiple alignment viewer Bioinformatics. 14: 380-381. PMID 9632837 DOI: 10.1093/Bioinformatics/14.4.380  0.306
1998 Brown NP, Sander C, Bork P. Frame: detection of genomic sequencing errors. Bioinformatics (Oxford, England). 14: 367-71. PMID 9632832 DOI: 10.1093/Bioinformatics/14.4.367  0.509
1998 Andrade MA, Sander C, Valencia A. Updated catalogue of homologues to human disease-related proteins in the yeast genome Febs Letters. 426: 7-16. PMID 9598968 DOI: 10.1016/S0014-5793(98)00277-4  0.518
1998 Holm L, Sander C. Touring protein fold space with Dali/FSSP Nucleic Acids Research. 26: 316-319. PMID 9399863 DOI: 10.1093/Nar/26.1.316  0.371
1998 Dodge C, Schneider R, Sander C. The HSSP database of protein structure-sequence alignments and family profiles. Nucleic Acids Research. 26: 313-5. PMID 9399862 DOI: 10.1093/Nar/26.1.313  0.648
1997 Andrade MA, Sander C. Bioinformatics: From genome data to biological knowledge Current Opinion in Biotechnology. 8: 675-683. PMID 9425655 DOI: 10.1016/S0958-1669(97)80118-8  0.397
1997 Andrade MA, Daruvar A, Casari G, Schneider R, Termier M, Sander C. Characterization of new proteins found by analysis of short open reading frames from the full yeast genome. Yeast (Chichester, England). 13: 1363-74. PMID 9392081 DOI: 10.1002/(Sici)1097-0061(199711)13:14<1363::Aid-Yea182>3.0.Co;2-8  0.652
1997 Andrade M, Casari G, de Daruvar A, Sander C, Schneider R, Tamames J, Valencia A, Ouzounis C. Sequence analysis of the Methanococcus jannaschii genome and the prediction of protein function. Computer Applications in the Biosciences : Cabios. 13: 481-3. PMID 9283767 DOI: 10.1093/Bioinformatics/13.4.481  0.685
1997 Hooft RWW, Sander C, Vriend G. Objectively judging the quality of a protein structure from a Ramachandran plot Computer Applications in the Biosciences. 13: 425-430. PMID 9283757 DOI: 10.1093/Bioinformatics/13.4.425  0.306
1997 Andrade MA, Casari G, Sander C, Valencia A. Classification of protein families and detection of the determinant residues with an improved self-organizing map. Biological Cybernetics. 76: 441-50. PMID 9263431 DOI: 10.1007/S004220050357  0.479
1997 Rost B, Schneider R, Sander C. Protein fold recognition by prediction-based threading. Journal of Molecular Biology. 270: 471-80. PMID 9237912 DOI: 10.1006/Jmbi.1997.1101  0.702
1997 Voss H, Benes V, Andrade MA, Valencia A, Rechmann S, Teodoru C, Schwager C, Paces V, Sander C, Ansorge W. DNA sequencing and analysis of 130 kb from yeast chromosome XV. Yeast (Chichester, England). 13: 655-72. PMID 9200815 DOI: 10.1002/(Sici)1097-0061(19970615)13:7<655::Aid-Yea120>3.0.Co;2-I  0.525
1997 Holm L, Sander C. An evolutionary treasure: unification of a broad set of amidohydrolases related to urease Proteins. 28: 72-82. PMID 9144792 DOI: 10.1002/(Sici)1097-0134(199705)28:1<72::Aid-Prot7>3.0.Co;2-L  0.339
1997 Holm L, Sander C. Dali/FSSP classification of three-dimensional protein folds Nucleic Acids Research. 25: 231-234. PMID 9016542 DOI: 10.1093/Nar/25.1.231  0.385
1997 Schneider R, de Daruvar A, Sander C. The HSSP database of protein structure-sequence alignments. Nucleic Acids Research. 25: 226-30. PMID 9016541 DOI: 10.1093/Nar/25.1.226  0.646
1996 Hooft RWW, Sander C, Scharf M, Vriend G. The PDBFINDER database: A summary of PDB, DSSP and HSSP information with added value Computer Applications in the Biosciences. 12: 525-529. PMID 9021272 DOI: 10.1093/Bioinformatics/12.6.525  0.372
1996 Ouzounis C, Casari G, Sander C, Tamames J, Valencia A. Computational comparisons of model genomes Trends in Biotechnology. 14: 280-285. PMID 8987458 DOI: 10.1016/0167-7799(96)10043-3  0.509
1996 Thomas DJ, Casari G, Sander C. The Prediction Of Protein Contacts From Multiple Sequence Alignments Protein Engineering. 9: 941-948. PMID 8961347 DOI: 10.1093/Protein/9.11.941  0.352
1996 Eide LG, Sander C, Prydz H. Sequencing and analysis of a 35·4 kb region on the left arm of chromosome IV from Saccharomyces cerevisiae reveal 23 open reading frames Yeast. 12: 1085-1090. PMID 8896275 DOI: 10.1002/(Sici)1097-0061(199609)12:10B<1085::Aid-Yea9>3.0.Co;2-0  0.355
1996 Rost B, Sander C. Bridging the Protein Sequence-Structure Gap by Structure Predictions Annual Review of Biophysics and Biomolecular Structure. 25: 113-136. PMID 8800466 DOI: 10.1146/Annurev.Bb.25.060196.000553  0.564
1996 Ouzounis C, Casari G, Valencia A, Sander C. Novelties from the complete genome of Mycoplasma genitalium [3] Molecular Microbiology. 20: 898-900. PMID 8793887 DOI: 10.1111/J.1365-2958.1996.Tb02529.X  0.459
1996 Casari G, De Daruvar A, Sander C, Schneider R. Bioinformatics and the discovery of gene function. Trends in Genetics : Tig. 12: 244-5. PMID 8763493 DOI: 10.1016/0168-9525(96)30057-7  0.586
1996 Holm L, Sander C. Alignment of three-dimensional protein structures: network server for database searching. Methods in Enzymology. 266: 653-662. PMID 8743712 DOI: 10.1016/S0076-6879(96)66041-8  0.366
1996 Tamames J, Ouzounis C, Sander C, Valencia A. Genomes with distinct function composition Febs Letters. 389: 96-101. PMID 8682215 DOI: 10.1016/0014-5793(96)00527-3  0.532
1996 Holm L, Sander C. Mapping the Protein Universe Science. 273: 595-602. PMID 8662544 DOI: 10.1126/Science.273.5275.595  0.376
1996 Holm L, Sander C. The FSSP database: fold classification based on structure-structure alignment of proteins. Nucleic Acids Research. 24: 206-209. PMID 8594580 DOI: 10.1093/Nar/24.1.206  0.365
1996 Schneider R, Sander C. The HSSP database of protein structure-sequence alignments. Nucleic Acids Research. 24: 201-5. PMID 8594579 DOI: 10.1093/nar/24.1.201  0.61
1996 Hooft RWW, Sander C, Vriend G. Verification of protein structures : Side-chain planarity Journal of Applied Crystallography. 29: 714-716. DOI: 10.1107/S0021889896008631  0.31
1995 Rost B, Sander C. Progress of 1D protein structure prediction at last. Proteins. 23: 295-300. PMID 8710823 DOI: 10.1002/Prot.340230304  0.557
1995 Holm L, Sander C. Dali: a network tool for protein structure comparison Trends in Biochemical Sciences. 20: 478-480. PMID 8578593 DOI: 10.1016/S0968-0004(00)89105-7  0.319
1995 Ouzounis C, Bork P, Casari G, Sander C. New protein functions in yeast chromosome VIII. Protein Science : a Publication of the Protein Society. 4: 2424-8. PMID 8563640 DOI: 10.1002/Pro.5560041121  0.508
1995 Ouzounis C, Kyrpides N, Sander C. Novel protein families in archaean genomes Nucleic Acids Research. 23: 565-570. PMID 7899076 DOI: 10.1093/Nar/23.4.565  0.391
1995 Voss H, Tamames J, Teodoru C, Valencia A, Sensen C, Wiemann S, Schwager C, Zimmermann J, Sander C, Ansorge W. Nucleotide sequence and analysis of the centromeric region of yeast chromosome IX. Yeast (Chichester, England). 11: 61-78. PMID 7762303 DOI: 10.1002/Yea.320110109  0.507
1995 Casari G, Sander C, Valencia A. A method to predict functional residues in proteins Nature Structural Biology. 2: 171-178. PMID 7749921 DOI: 10.1038/Nsb0295-171  0.523
1995 Casari G, Andrade MA, Bork P, Boyle J, Daruvar A, Ouzounis C, Schneider R, Tamames J, Valencia A, Sander C. Challenging times for bioinformatics. Nature. 376: 647-8. PMID 7651513 DOI: 10.1038/376647A0  0.671
1995 Hobohm U, Sander C. A Sequence Property Approach to Searching Protein Databases Journal of Molecular Biology. 251: 390-399. PMID 7650738 DOI: 10.1006/Jmbi.1995.0442  0.366
1995 Konstantopoulou I, Ouzounis CA, Drosopoulou E, Yiangou M, Sideras P, Sander C, Scouras ZG. A Drosophila hsp70 gene contains long, antiparallel, coupled open reading frames (LAC ORFs) conserved in homologous loci Journal of Molecular Evolution. 41: 414-420. PMID 7563128 DOI: 10.1007/Bf00160312  0.309
1995 Bork P, Holm L, Koonin EV, Sander C. The cytidylyltransferase superfamily: identification of the nucleotide-binding site and fold prediction. Proteins. 22: 259-66. PMID 7479698 DOI: 10.1002/Prot.340220306  0.486
1995 Bork P, Ouzounis C, Casari G, Schneider R, Sander C, Dolan M, Gilbert W, Gillevet PM. Exploring the Mycoplasma capricolum genome: a minimal cell reveals its physiology. Molecular Microbiology. 16: 955-67. PMID 7476192 DOI: 10.1111/J.1365-2958.1995.Tb02321.X  0.682
1994 Koonin EV, Bork P, Sander C. Yeast chromosome III: new gene functions. The Embo Journal. 13: 493-503. PMID 8313894 DOI: 10.1002/J.1460-2075.1994.Tb06287.X  0.548
1994 Meitinger T, Meindl A, Bork P, Rost B, Sander C, Haasemann M, Murken J. Molecular modelling of the Norrie disease protein predicts a cystine knot growth factor tertiary structure. Nature Genetics. 5: 376-80. PMID 8298646 DOI: 10.1038/Ng1293-376  0.49
1994 Rost B, Sander C, Schneider R. Redefining the goals of protein secondary structure prediction. Journal of Molecular Biology. 235: 13-26. PMID 8289237 DOI: 10.1016/S0022-2836(05)80007-5  0.7
1994 Göbel U, Sander C, Schneider R, Valencia A. Correlated mutations and residue contacts in proteins. Proteins. 18: 309-17. PMID 8208723 DOI: 10.1002/Prot.340180402  0.7
1994 Rost B, Sander C, Schneider R. PHD--an automatic mail server for protein secondary structure prediction. Computer Applications in the Biosciences : Cabios. 10: 53-60. PMID 8193956 DOI: 10.1093/Bioinformatics/10.1.53  0.72
1994 Shindyalov IN, Kolchanov NA, Sander C. Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations? Protein Engineering. 7: 349-358. PMID 8177884 DOI: 10.1093/Protein/7.3.349  0.387
1994 Vriend G, Sander C, Stouten PFW. A novel search method for protein sequence-structure relations using property profiles Protein Engineering. 7: 23-29. PMID 8140091 DOI: 10.1093/Protein/7.1.23  0.378
1994 Rost B, Sander C. Combining evolutionary information and neural networks to predict protein secondary structure. Proteins. 19: 55-72. PMID 8066087 DOI: 10.1002/Prot.340190108  0.558
1994 Ouzounis C, Bork P, Sander C. The modular structure of NifU proteins. Trends in Biochemical Sciences. 19: 199-200. PMID 8048161 DOI: 10.1016/0968-0004(94)90021-3  0.483
1994 Hobohm U, Sander C. Enlarged representative set of protein structures Protein Science. 3: 522-524. PMID 8019422 DOI: 10.1002/Pro.5560030317  0.335
1994 Holm L, Sander C. Parser for protein folding units. Proteins. 19: 256-268. PMID 7937738 DOI: 10.1002/Prot.340190309  0.314
1994 Holm L, Sander C. Searching protein structure databases has come of age. Proteins. 19: 165-173. PMID 7937731 DOI: 10.1002/Prot.340190302  0.365
1994 Sander C, Schneider R. The HSSP database of protein structure-sequence alignments. Nucleic Acids Research. 22: 3597-9. PMID 7937066  0.607
1994 Bork P, Holm L, Sander C. The immunoglobulin fold. Structural classification, sequence patterns and common core. Journal of Molecular Biology. 242: 309-20. PMID 7932691 DOI: 10.1006/Jmbi.1994.1582  0.479
1994 Rost B, Sander C. Conservation and prediction of solvent accessibility in protein families Proteins. 20: 216-226. PMID 7892171 DOI: 10.1002/Prot.340200303  0.539
1994 Hobohm U, Houthaeve T, Sander C. Amino Acid Analysis and Protein Database Compositional Search as a Rapid and Inexpensive Method to Identify Proteins Analytical Biochemistry. 222: 202-209. PMID 7856850 DOI: 10.1006/Abio.1994.1474  0.333
1994 Rost B, Sander C. Structure prediction of proteins--where are we now? Current Opinion in Biotechnology. 5: 372-380. PMID 7765169 DOI: 10.1016/0958-1669(94)90045-0  0.538
1994 Sander C. Design of protein structures: Helix bundles and beyond Trends in Biotechnology. 12: 163-167. PMID 7764898 DOI: 10.1016/0167-7799(94)90077-9  0.325
1994 Holm L, Sander C, Rüterjans H, Schnarr M, Fogh R, Boelens R, Kaptein R. LexA repressor and iron uptake regulator from Escherichia coli: new members of the CAP-like DNA binding domain superfamily. Protein Engineering. 7: 1449-53. PMID 7716155 DOI: 10.1093/Protein/7.12.1449  0.37
1994 Scharf M, Schneider R, Casari G, Bork P, Valencia A, Ouzounis C, Sander C. GeneQuiz: a workbench for sequence analysis. Proceedings / ... International Conference On Intelligent Systems For Molecular Biology ; Ismb. International Conference On Intelligent Systems For Molecular Biology. 2: 348-53. PMID 7584411  0.668
1994 Koonin EV, Bork P, Sander C. A novel RNA-binding motif in omnipotent suppressors of translation termination, ribosomal proteins and a ribosome modification enzyme? Nucleic Acids Research. 22: 2166-7. PMID 7518079 DOI: 10.1093/Nar/22.11.2166  0.5
1994 Hooft RWW, Sander C, Vriend G. Reconstruction of Symmetry-Related Molecules from Protein Data Bank (PDB) Files Journal of Applied Crystallography. 27: 1006-1009. DOI: 10.1107/S0021889894007764  0.335
1994 Bork P, Ouzounis C, Sander C. From genome sequences to protein function Current Opinion in Structural Biology. 4: 393-403. DOI: 10.1016/S0959-440X(94)90109-0  0.53
1993 Holmes KC, Sander C, Valencia A. A new ATP-binding fold in actin, hexokinase and Hsc70. Trends in Cell Biology. 3: 53-9. PMID 14731729 DOI: 10.1016/0962-8924(93)90161-S  0.762
1993 Rost B, Schneider R, Sander C. Progress in protein structure prediction? Trends in Biochemical Sciences. 18: 120-3. PMID 8493721 DOI: 10.1016/0968-0004(93)90017-H  0.707
1993 Ouzounis C, Sander C. Homology of the NifS family of proteins to a new class of pyridoxal phosphate-dependent enzymes Febs Letters. 322: 159-164. PMID 8482384 DOI: 10.1016/0014-5793(93)81559-I  0.31
1993 Stouten PFW, Sander C, Wittinghofer A, Valencia A. How Does The Switch-Ii Region Of G-Domains Work Febs Letters. 320: 1-6. PMID 8462668 DOI: 10.1016/0014-5793(93)81644-F  0.452
1993 Holm L, Sander C. Structural alignment of globins, phycocyanins and colicin A. Febs Letters. 315: 301-306. PMID 8422921 DOI: 10.1016/0014-5793(93)81183-Z  0.348
1993 Bork P, Sander C, Valencia A. Convergent evolution of similar enzymatic function on different protein folds: The hexokinase, ribokinase, and galactokinase families of sugar kinases Protein Science. 2: 31-40. PMID 8382990 DOI: 10.1002/Pro.5560020104  0.561
1993 Holm L, Sander C. Protein structure comparison by alignment of distance matrices. Journal of Molecular Biology. 233: 123-138. PMID 8377180 DOI: 10.1006/Jmbi.1993.1489  0.354
1993 Rost B, Sander C. Improved prediction of protein secondary structure by use of sequence profiles and neural networks Proceedings of the National Academy of Sciences of the United States of America. 90: 7558-7562. PMID 8356056 DOI: 10.1073/Pnas.90.16.7558  0.558
1993 Ouzounis C, Sander C, Scharf M, Schneider R. Prediction of protein structure by evaluation of sequence-structure fitness. Aligning sequences to contact profiles derived from three-dimensional structures. Journal of Molecular Biology. 232: 805-25. PMID 8355272 DOI: 10.1006/Jmbi.1993.1433  0.655
1993 Rost B, Sander C. Prediction of Protein Secondary Structure at Better than 70% Accuracy Journal of Molecular Biology. 232: 584-599. PMID 8345525 DOI: 10.1006/Jmbi.1993.1413  0.554
1993 Sander C, Schneider R. The HSSP data base of protein structure-sequence alignments. Nucleic Acids Research. 21: 3105-9. PMID 8332531  0.611
1993 Rost B, sander C. Secondary structure prediction of all-helical proteins in two states. Protein Engineering. 6: 831-836. PMID 8309930 DOI: 10.1093/Protein/6.8.831  0.517
1993 Hobohm U, Sander C. Does the HIV Nef protein mimic the MHC Febs Letters. 333: 211-213. PMID 8224180 DOI: 10.1016/0014-5793(93)80655-E  0.336
1993 Reizer J, Reizer A, Saier MH, Bork P, Sander C. Exopolyphosphate phosphatase and guanosine pentaphosphate phosphatase belong to the sugar kinase/actin/hsp 70 superfamily. Trends in Biochemical Sciences. 18: 247-8. PMID 8212131 DOI: 10.1016/0968-0004(93)90172-J  0.386
1993 Bork P, Sander C. A hybrid protein kinase-RNase in an interferon-induced pathway? Febs Letters. 334: 149-52. PMID 7693513 DOI: 10.1016/0014-5793(93)81701-Z  0.489
1993 Rost B, Sander C. Jury returns on structure prediction. Nature. 360: 540. PMID 1281284 DOI: 10.1038/360540B0  0.485
1992 Palme K, Diefenthal T, Vingron M, Sander C, Schell J. Molecular cloning and structural analysis of genes from Zea mays (L.) coding for members of the ras-related ypt gene family. Proceedings of the National Academy of Sciences of the United States of America. 89: 787-791. PMID 1731354 DOI: 10.1073/Pnas.89.2.787  0.317
1992 Vriend G, Sander C. Detection of common three-dimensional substructures in proteins. Proteins. 11: 52-8. PMID 1660134 DOI: 10.1002/Prot.340110107  0.323
1992 Bork P, Ouzounis C, Sander C, Scharf M, Schneider R, Sonnhammer E. What's in a genome? Nature. 358: 287. PMID 1641000 DOI: 10.1038/358287A0  0.645
1992 Holm L, Sander C. Evaluation of protein models by atomic solvation preference Journal of Molecular Biology. 225: 93-105. PMID 1583696 DOI: 10.1016/0022-2836(92)91028-N  0.358
1992 Holm L, Sander C. Fast and simple Monte Carlo algorithm for side chain optimization in proteins: application to model building by homology. Proteins. 14: 213-223. PMID 1409569 DOI: 10.1002/Prot.340140208  0.317
1992 Bork P, Sander C, Valencia A. An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins Proceedings of the National Academy of Sciences of the United States of America. 89: 7290-7294. PMID 1323828 DOI: 10.1073/Pnas.89.16.7290  0.612
1992 Bork P, Sander C. A large domain common to sperm receptors (Zp2 and Zp3) and TGF-beta type III receptor. Febs Letters. 300: 237-40. PMID 1313375 DOI: 10.1016/0014-5793(92)80853-9  0.439
1992 Holm L, Ouzounis C, Sander C, Tuparev G, Vriend G. A database of protein structure families with common folding motifs Protein Science. 1: 1691-1698. PMID 1304898 DOI: 10.1002/Pro.5560011217  0.376
1992 Bork P, Ouzounis C, Sander C, Scharf M, Schneider R, Sonnhammer E. Comprehensive sequence analysis of the 182 predicted open reading frames of yeast chromosome III. Protein Science : a Publication of the Protein Society. 1: 1677-90. PMID 1304897 DOI: 10.1002/Pro.5560011216  0.706
1992 Hobohm U, Scharf M, Schneider R, Sander C. Selection of representative protein data sets. Protein Science : a Publication of the Protein Society. 1: 409-17. PMID 1304348 DOI: 10.1002/Pro.5560010313  0.64
1992 Rost B, Sander C. EXERCISING MULTI-LAYERED NETWORKS ON PROTEIN SECONDARY STRUCTURE International Journal of Neural Systems. 3: 209-220. DOI: 10.1142/S0129065792000541  0.504
1991 Valencia A, Kjeldgaard M, Pai EF, Sander C. GTPase domains of ras p21 oncogene protein and elongation factor Tu: analysis of three-dimensional structures, sequence families, and functional sites. Proceedings of the National Academy of Sciences of the United States of America. 88: 5443-7. PMID 2052624 DOI: 10.1073/Pnas.88.12.5443  0.496
1991 Grandori R, Sander C. Identification by computer sequence analysis of transcriptional regulator proteins in Dictyostelium discoideum and Serratia marcescens. Nucleic Acids Research. 19: 2359-62. PMID 2041776 DOI: 10.1093/Nar/19.9.2359  0.406
1991 Valencia A, Chardin P, Wittinghofer A, Sander C. The ras protein family: Evolutionary tree and role of conserved amino acids Biochemistry. 30: 4637-4648. PMID 2029511 DOI: 10.1021/Bi00233A001  0.447
1991 Sander C, Schneider R. Database of homology-derived protein structures and the structural meaning of sequence alignment. Proteins. 9: 56-68. PMID 2017436 DOI: 10.1002/Prot.340090107  0.65
1991 Holm L, Sander C. Database algorithm for generating protein backbone and side-chain co-ordinates from a Cα trace: Application to model building and detection of co-ordinate errors Journal of Molecular Biology. 218: 183-194. PMID 2002501 DOI: 10.1016/0022-2836(91)90883-8  0.324
1991 Ouzounis C, Sander C. A structure-derived sequence pattern for the detection of type I copper binding domains in distantly related proteins Febs Letters. 279: 73-78. PMID 1995346 DOI: 10.1016/0014-5793(91)80254-Z  0.344
1991 Hubbard TJP, Sander C. The role of heat-shock and chaperone proteins in protein folding: possible molecular mechanisms. Protein Engineering. 4: 711-717. PMID 1798696 DOI: 10.1093/Protein/4.7.711  0.306
1991 Sander C. De novo design of proteins Current Opinion in Structural Biology. 1: 630-637. DOI: 10.1016/S0959-440X(05)80088-0  0.304
1989 Godzik A, Sander C. Conservation of residue interactions in a family of Ca-binding proteins Protein Engineering. 2: 589-596. PMID 2813336 DOI: 10.1093/Protein/2.8.589  0.344
1989 Frömmel C, Sander C. Thermitase, a thermostable subtilisin: Comparison of predicted and experimental structures and the molecular cause of thermostability Proteins. 5: 22-37. PMID 2664764 DOI: 10.1002/Prot.340050105  0.341
1989 Bussian BM, Sander C. How to determine protein secondary structure in solution by Raman spectroscopy: practical guide and test case DNase I Biochemistry. 28: 4271-4277. DOI: 10.1021/Bi00436A023  0.339
1985 Levitt M, Sander C, Stern PS. Protein normal-mode dynamics: trypsin inhibitor, crambin, ribonuclease and lysozyme. Journal of Molecular Biology. 181: 423-447. PMID 2580101 DOI: 10.1016/0022-2836(85)90230-X  0.428
1985 Levitt M, Sander C, Stern PS. Jaws. A film of enzyme dynamics Fresenius' Zeitschrift FüR Analytische Chemie. 321: 645-645. DOI: 10.1007/Bf00489623  0.42
1984 Kabsch W, Sander C. On the use of sequence homologies to predict protein structure: identical pentapeptides can have completely different conformations Proceedings of the National Academy of Sciences of the United States of America. 81: 1075-1078. PMID 6422466 DOI: 10.1073/Pnas.81.4.1075  0.399
1983 Kabsch W, Sander C. How good are predictions of protein secondary structure Febs Letters. 155: 179-182. PMID 6852232 DOI: 10.1016/0014-5793(82)80597-8  0.356
1983 Kabsch W, Sander C. Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features Biopolymers. 22: 2577-2637. PMID 6667333 DOI: 10.1002/Bip.360221211  0.312
1983 Gallwitz D, Donath C, Sander C. A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product Nature. 306: 704-707. PMID 6318115 DOI: 10.1038/306704A0  0.345
1982 Hol WG, Halie LM, Sander C. Dipoles of the alpha-helix and beta-sheet: their role in protein folding. Nature. 294: 532-6. PMID 7312043 DOI: 10.1038/294532A0  0.302
1980 Lifson S, Sander C. Specific recognition in the tertiary structure of beta-sheets of proteins. Journal of Molecular Biology. 139: 627-39. PMID 7411635 DOI: 10.1016/0022-2836(80)90052-2  0.579
1980 Sander C, Schulz GE. Degeneracy of the information contained in amino acid sequences: evidence from overlaid genes. Journal of Molecular Evolution. 13: 245-52. PMID 228047 DOI: 10.1007/Bf01739483  0.315
1979 Lifson S, Sander C. Antiparallel and parallel beta-strands differ in amino acid residue preferences. Nature. 282: 109-11. PMID 503185 DOI: 10.1038/282109A0  0.597
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