| Year |
Citation |
Score |
| 2014 |
North TW, Villalobos A, Hurwitz SJ, Deere JD, Higgins J, Chatterjee P, Tao S, Kauffman RC, Luciw PA, Kohler JJ, Schinazi RF. Enhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decay kinetics. Antimicrobial Agents and Chemotherapy. 58: 3927-33. PMID 24777106 DOI: 10.1128/Aac.02522-14 |
0.746 |
|
| 2014 |
Deere JD, Kauffman RC, Cannavo E, Higgins J, Villalobos A, Adamson L, Schinazi RF, Luciw PA, North TW. Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART. Plos One. 9: e87914. PMID 24505331 DOI: 10.1371/Journal.Pone.0087914 |
0.768 |
|
| 2014 |
Wadford DA, Kauffman RC, Deere JD, Aoki ST, Stanton RA, Higgins J, Van Rompay KK, Villalobos A, Nettles JH, Schinazi RF, Pedersen NC, North TW. Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV. Plos One. 9: e86997. PMID 24498008 DOI: 10.1371/Journal.Pone.0086997 |
0.775 |
|
| 2013 |
Gavegnano C, Detorio MA, Bassit L, Hurwitz SJ, North TW, Schinazi RF. Cellular pharmacology and potency of HIV-1 nucleoside analogs in primary human macrophages. Antimicrobial Agents and Chemotherapy. 57: 1262-9. PMID 23263005 DOI: 10.1128/Aac.02012-12 |
0.496 |
|
| 2011 |
Deere JD, Schinazi RF, North TW. Simian immunodeficiency virus macaque models of HIV latency. Current Opinion in Hiv and Aids. 6: 57-61. PMID 21242894 DOI: 10.1097/Coh.0B013E32834086Ce |
0.798 |
|
| 2010 |
Deere JD, Higgins J, Cannavo E, Villalobos A, Adamson L, Fromentin E, Schinazi RF, Luciw PA, North TW. Viral decay kinetics in the highly active antiretroviral therapy-treated rhesus macaque model of AIDS. Plos One. 5: e11640. PMID 20668516 DOI: 10.1371/Journal.Pone.0011640 |
0.825 |
|
| 2010 |
North TW, Higgins J, Deere JD, Hayes TL, Villalobos A, Adamson L, Shacklett BL, Schinazi RF, Luciw PA. Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS. Journal of Virology. 84: 2913-22. PMID 20032180 DOI: 10.1128/Jvi.02356-09 |
0.816 |
|
| 2007 |
Van Rompay KK, Johnson JA, Blackwood EJ, Singh RP, Lipscomb J, Matthews TB, Marthas ML, Pedersen NC, Bischofberger N, Heneine W, North TW. Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection. Retrovirology. 4: 25. PMID 17417971 DOI: 10.1186/1742-4690-4-25 |
0.57 |
|
| 2007 |
Duong YT, Meadows DC, Srivastava IK, Gervay-Hague J, North TW. Direct inactivation of human immunodeficiency virus type 1 by a novel small-molecule entry inhibitor, DCM205. Antimicrobial Agents and Chemotherapy. 51: 1780-6. PMID 17307982 DOI: 10.1128/Aac.01001-06 |
0.768 |
|
| 2005 |
Meadows DC, Mathews TB, North TW, Hadd MJ, Kuo CL, Neamati N, Gervay-Hague J. Synthesis and biological evaluation of geminal disulfones as HIV-1 integrase inhibitors. Journal of Medicinal Chemistry. 48: 4526-34. PMID 15999991 DOI: 10.1021/Jm049171V |
0.396 |
|
| 2005 |
North TW, Van Rompay KK, Higgins J, Matthews TB, Wadford DA, Pedersen NC, Schinazi RF. Suppression of virus load by highly active antiretroviral therapy in rhesus macaques infected with a recombinant simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1. Journal of Virology. 79: 7349-54. PMID 15919889 DOI: 10.1128/Jvi.79.12.7349-7354.2005 |
0.808 |
|
| 2005 |
Joshi PJ, North TW, Prasad VR. Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 677-86. PMID 15851006 DOI: 10.1016/J.Ymthe.2005.01.013 |
0.557 |
|
| 2004 |
Hofman MJ, Higgins J, Matthews TB, Pedersen NC, Tan C, Schinazi RF, North TW. Efavirenz therapy in rhesus macaques infected with a chimera of simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1. Antimicrobial Agents and Chemotherapy. 48: 3483-90. PMID 15328115 DOI: 10.1128/Aac.48.9.3483-3490.2004 |
0.735 |
|
| 2003 |
Pedersen NC, North TW, Rigg R, Reading C, Higgins J, Leutenegger C, Henderson GL. 16alpha-Bromo-epiandrosterone therapy modulates experimental feline immunodeficiency virus viremia: initial enhancement leading to long-term suppression. Veterinary Immunology and Immunopathology. 94: 133-48. PMID 12909410 DOI: 10.1016/S0165-2427(03)00081-3 |
0.41 |
|
| 2003 |
Giuffre AC, Higgins J, Buckheit RW, North TW. Susceptibilities of simian immunodeficiency virus to protease inhibitors. Antimicrobial Agents and Chemotherapy. 47: 1756-9. PMID 12709355 DOI: 10.1128/Aac.47.5.1756-1759.2003 |
0.719 |
|
| 2003 |
Murry JP, Higgins J, Matthews TB, Huang VY, Van Rompay KK, Pedersen NC, North TW. Reversion of the M184V mutation in simian immunodeficiency virus reverse transcriptase is selected by tenofovir, even in the presence of lamivudine. Journal of Virology. 77: 1120-30. PMID 12502828 DOI: 10.1128/Jvi.77.2.1120-1130.2003 |
0.434 |
|
| 2002 |
Van Rompay KK, Matthews TB, Higgins J, Canfield DR, Tarara RP, Wainberg MA, Schinazi RF, Pedersen NC, North TW. Virulence and reduced fitness of simian immunodeficiency virus with the M184V mutation in reverse transcriptase. Journal of Virology. 76: 6083-92. PMID 12021341 DOI: 10.1128/Jvi.76.12.6083-6092.2002 |
0.488 |
|
| 2002 |
Auwerx J, North TW, Preston BD, Klarmann GJ, De Clercq E, Balzarini J. Chimeric human immunodeficiency virus type 1 and feline immunodeficiency virus reverse transcriptases: role of the subunits in resistance/sensitivity to non-nucleoside reverse transcriptase inhibitors. Molecular Pharmacology. 61: 400-6. PMID 11809865 DOI: 10.1124/Mol.61.2.400 |
0.567 |
|
| 2001 |
Leutenegger CM, Higgins J, Matthews TB, Tarantal AF, Luciw PA, Pedersen NC, North TW. Real-time TaqMan PCR as a specific and more sensitive alternative to the branched-chain DNA assay for quantitation of simian immunodeficiency virus RNA. Aids Research and Human Retroviruses. 17: 243-51. PMID 11177407 DOI: 10.1089/088922201750063160 |
0.309 |
|
| 2000 |
Klarmann GJ, Smith RA, Schinazi RF, North TW, Preston BD. Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site Journal of Biological Chemistry. 275: 359-366. PMID 10617626 DOI: 10.1074/Jbc.275.1.359 |
0.475 |
|
| 1998 |
Elder JH, Dean GA, Hoover EA, Hoxie JA, Malim MH, Mathes L, Neil JC, North TW, Sparger E, Tompkins MB, Tompkins WA, Yamamoto J, Yuhki N, Pedersen NC, Miller RH. Lessons from the cat: feline immunodeficiency virus as a tool to develop intervention strategies against human immunodeficiency virus type 1. Aids Research and Human Retroviruses. 14: 797-801. PMID 9643379 DOI: 10.1089/Aid.1998.14.797 |
0.509 |
|
| 1997 |
Hartmann K, Ferk G, North TW, Pedersen NC. Toxicity associated with high dosage 9-[(2R, 5R-2,5-dihydro-5-phosphonomethoxy)-2-furanyl]adenine therapy and attempts to abort early FIV infection Antiviral Research. 36: 11-25. PMID 9330757 DOI: 10.1016/S0166-3542(97)00030-2 |
0.369 |
|
| 1996 |
Arts EJ, Stetor SR, Li X, Rausch JW, Howard KJ, Ehresmann B, North TW, Wöhrl BM, Goody RS, Wainberg MA, Le Grice SFJ. Initiation of (-) strand DNA synthesis from tRNALys3 on lentiviral RNAs: Implications of specific HIV-1 RNA-tRNALys3 interactions inhibiting primer utilization by retroviral reverse transcriptases Proceedings of the National Academy of Sciences of the United States of America. 93: 10063-10068. PMID 8816751 DOI: 10.1073/Pnas.93.19.10063 |
0.567 |
|
| 1996 |
Chen H, McBroom DG, Zhu YQ, Gold L, North TW. Inhibitory RNA ligand to reverse transcriptase from feline immunodeficiency virus Biochemistry. 35: 6923-6930. PMID 8639644 DOI: 10.1021/Bi9600106 |
0.428 |
|
| 1996 |
LaCasse RA, Remington KM, North TW. The Mutation Frequency of Feline Immunodeficiency Virus Enhanced by 3′-Azido-3′-deoxythymidine Journal of Acquired Immune Deficiency Syndromes. 12: 26-32. PMID 8624757 |
0.434 |
|
| 1995 |
North TW, Lacasse RA. Testing anti–HIV drugs in the FIV model Nature Medicine. 1: 410-411. PMID 7585083 DOI: 10.1038/nm0595-410 |
0.331 |
|
| 1994 |
North TW, Hansen GL, Zhu Y, Griffin JA, Shih CK. Expression of reverse transcriptase from feline immunodeficiency virus in Escherichia coli Antimicrobial Agents and Chemotherapy. 38: 388-391. PMID 7514859 |
0.426 |
|
| 1993 |
Barlough JE, North TW, Oxford CL, Remington KM, Dandekar S, Nixon Ellis M, Pedersen NC. Feline immunodeficiency virus infection of cats as a model to test the effect of certain in vitro selection pressures on the infectivity and virulence of resultant lentivirus variants Antiviral Research. 22: 259-272. PMID 8279815 DOI: 10.1016/0166-3542(93)90036-I |
0.372 |
|
| 1992 |
Cronn RC, Whitmer JD, North TW. RNase H activity associated with reverse transcriptase from feline immunodeficiency virus. Journal of Virology. 66: 1215-8. PMID 1370549 |
0.501 |
|
| 1991 |
Remington KM, Chesebro B, Wehrly K, Pedersen NC, North TW. Mutants of feline immunodeficiency virus resistant to 3′ - azido-3′ -deoxythymidine Journal of Virology. 65: 308-312. PMID 1845891 DOI: 10.1128/Jvi.65.1.308-312.1991 |
0.375 |
|
| 1991 |
Remington KM, Chesebro B, Wehrly K, Pedersen NC, North TW. Mutants of feline immunodeficiency virus resistant to 3'-azido-3'-deoxythymidine. Journal of Virology. 65: 308-312. DOI: 10.1128/jvi.65.1.308-312.1991 |
0.439 |
|
| 1990 |
North TW, Cronn RC, Remington KM, Tandberg RT. Direct comparisons of inhibitor sensitivities of reverse transcriptases from feline and human immunodeficiency viruses Antimicrobial Agents and Chemotherapy. 34: 1505-1507. PMID 1699491 DOI: 10.1128/Aac.34.8.1505 |
0.443 |
|
| 1990 |
North TW, Cronn RC, Remington KM, Tandberg RT, Judd RC. Characterization of reverse transcriptase from feline immunodeficiency virus Journal of Biological Chemistry. 265: 5121-5128. PMID 1690735 |
0.582 |
|
| 1989 |
North TW, North GLT, Pedersen NC. Feline immunodeficiency virus, a model for reverse transcriptase-targeted chemotherapy for acquired immune deficiency syndrome Antimicrobial Agents and Chemotherapy. 33: 915-919. PMID 2475068 DOI: 10.1128/Aac.33.6.915 |
0.503 |
|
| 1984 |
North TW. Inhibition of Herpes Simplex Virus Replication by Purine Deoxyribonucleosides Cancer Research. 44: 1415-1419. PMID 6322976 |
0.479 |
|
| 1983 |
North TW, O'Connor L, Abushanab E, Panzica RP. Effects of chirality in 9-(2-hydroxy-3-nonyl)adenine upon deoxyribonucleic acid synthesis in herpes simplex virus-infected cells Biochemical Pharmacology. 32: 3541-3546. PMID 6316987 DOI: 10.1016/0006-2952(83)90300-3 |
0.395 |
|
| 1981 |
North TW, Mathews CK. Tetrahydrouridine specifically facilitates deoxycytidine incorporation into herpes simplex virus DNA Journal of Virology. 37: 987-993. PMID 6262539 |
0.458 |
|
| 1980 |
Shannon WM, Arnett G, Schabel FM, North TW, Cohen SS. Erythro-9-(2-hydroxy-3-nonyl)adenine alone and in combination with 9-β-D-arabinofuranosyladenine in treatment of systemic herpesvirus infections in mice Antimicrobial Agents and Chemotherapy. 18: 598-603. PMID 6255863 |
0.361 |
|
| 1979 |
North TW, Cohen SS. Aranucleosides and aranucleotides in viral chemotherapy Pharmacology and Therapeutics. 4: 81-108. PMID 88745 DOI: 10.1016/0163-7258(79)90016-0 |
0.411 |
|
| 1978 |
North TW, Cohen SS. Erythro-9-(2-hydroxy-3-nonyl)adenine as a specific inhibitor of herpes simplex virus replication in the presence and absence of adenosine analogues Proceedings of the National Academy of Sciences of the United States of America. 75: 4684-4688. PMID 216993 |
0.499 |
|
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