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Boyi Gan, Ph.D. - Publications

Affiliations: 
2006 Cornell University, Ithaca, NY, United States 
 2011- Experimental Radiation Oncology The University of Texas MD Anderson Cancer Center 
Area:
Cell Biology, Molecular Biology, Genetics
Website:
https://faculty.mdanderson.org/profiles/boyi_gan.html
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mao C, Lei G, Horbath A, Wang M, Lu Z, Yan Y, Liu X, Kondiparthi L, Chen X, Cheng J, Li Q, Xu Z, Zhuang L, Fang B, Marszalek JR, ... ... Gan B, et al. Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers. Molecular Cell. 84: 1964-1979.e6. PMID 38759628 DOI: 10.1016/j.molcel.2024.04.009  0.326
2024 Jiang D, Guo Y, Wang T, Wang L, Yan Y, Xia L, Bam R, Yang Z, Lee H, Iwawaki T, Gan B, Koong AC. IRE1α determines ferroptosis sensitivity through regulation of glutathione synthesis. Nature Communications. 15: 4114. PMID 38750057 DOI: 10.1038/s41467-024-48330-0  0.339
2024 Nie L, Wang C, Huang M, Liu X, Feng X, Tang M, Li S, Hang Q, Teng H, Shen X, Ma L, Gan B, Chen J. DePARylation is critical for S phase progression and cell survival. Elife. 12. PMID 38578205 DOI: 10.7554/eLife.89303  0.322
2023 Nie L, Wang C, Liu X, Huang M, Feng X, Tang M, Li S, Hang Q, Teng H, Shen X, Ma L, Gan B, Chen J. DePARylation is critical for S phase progression and cell survival. Biorxiv : the Preprint Server For Biology. PMID 37577639 DOI: 10.1101/2023.07.31.551317  0.322
2021 Liu X, Zhang Y, Zhuang L, Olszewski K, Gan B. NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edged sword in cellular redox regulation. Genes & Diseases. 8: 731-745. PMID 34522704 DOI: 10.1016/j.gendis.2020.11.010  0.302
2021 Zhang Y, Swanda RV, Nie L, Liu X, Wang C, Lee H, Lei G, Mao C, Koppula P, Cheng W, Zhang J, Xiao Z, Zhuang L, Fang B, Chen J, ... ... Gan B, et al. mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation. Nature Communications. 12: 1589. PMID 33707434 DOI: 10.1038/s41467-021-21841-w  0.3
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Gan B, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.429
2020 Lee H, Zhuang L, Gan B. Energy stress inhibits ferroptosis via AMPK. Molecular & Cellular Oncology. 7: 1761242. PMID 32944623 DOI: 10.1080/23723556.2020.1761242  0.358
2020 Chauhan AS, Zhuang L, Gan B. Spatial control of AMPK signaling at subcellular compartments. Critical Reviews in Biochemistry and Molecular Biology. 1-16. PMID 32069425 DOI: 10.1080/10409238.2020.1727840  0.321
2020 Lee H, Zandkarimi F, Zhang Y, Meena JK, Kim J, Zhuang L, Tyagi S, Ma L, Westbrook TF, Steinberg GR, Nakada D, Stockwell BR, Gan B. Energy-stress-mediated AMPK activation inhibits ferroptosis. Nature Cell Biology. 22: 225-234. PMID 32029897 DOI: 10.1038/S41556-020-0461-8  0.369
2020 Lei G, Zhang Y, Koppula P, Liu X, Zhang J, Lin SH, Ajani JA, Xiao Q, Liao Z, Wang H, Gan B. The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression. Cell Research. PMID 31949285 DOI: 10.1038/S41422-019-0263-3  0.388
2020 Zhang Y, Shi J, Xiao Z, Lei G, Liu X, Lee H, Koppula P, Cheng W, Mao C, Zhuang L, Ma L, Li W, Gan B. Abstract 2415: H2A monoubiquitination links glucose availability to epigenetic regulation of the endoplasmic reticulum stress induced cell death in cancer Cancer Research. 80: 2415-2415. DOI: 10.1158/1538-7445.Am2020-2415  0.37
2020 Lei G, Zhang Y, Koppula P, Liu X, Lin SH, Liao Z, Wang H, Gan B. Abstract 2413: Ferroptosis plays an important role in the radiotherapy-induced tumor suppression and radioresistance Cancer Research. 80: 2413-2413. DOI: 10.1158/1538-7445.Am2020-2413  0.415
2019 Gan B. DUBbing Ferroptosis in Cancer Cells. Cancer Research. 79: 1749-1750. PMID 30987975 DOI: 10.1158/0008-5472.Can-19-0487  0.372
2019 Zhang Y, Koppula P, Gan B. Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1. Cell Cycle (Georgetown, Tex.). PMID 30907299 DOI: 10.1080/15384101.2019.1597506  0.422
2018 Kim J, Piao HL, Kim BJ, Yao F, Han Z, Wang Y, Xiao Z, Siverly AN, Lawhon SE, Ton BN, Lee H, Zhou Z, Gan B, Nakagawa S, Ellis MJ, et al. Long noncoding RNA MALAT1 suppresses breast cancer metastasis. Nature Genetics. PMID 30349115 DOI: 10.1038/S41588-018-0252-3  0.338
2017 Koppula P, Zhang Y, Shi J, Li W, Gan B. The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate. The Journal of Biological Chemistry. PMID 28630042 DOI: 10.1074/Jbc.M117.798405  0.37
2017 Dai F, Lee H, Zhang Y, Zhuang L, Yao H, Xi Y, Xiao ZD, You MJ, Li W, Su X, Gan B. BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response. Proceedings of the National Academy of Sciences of the United States of America. PMID 28275095 DOI: 10.1073/Pnas.1619588114  0.393
2016 Xiao ZD, Liu X, Zhuang L, Gan B. NBR2: A former junk gene emerges as a key player in tumor suppression. Molecular & Cellular Oncology. 3: e1187322. PMID 27652330 DOI: 10.1080/23723556.2016.1187322  0.358
2016 Kim J, Siverly AN, Chen D, Wang M, Yuan Y, Wang Y, Lee H, Zhang J, Muller WJ, Liang H, Gan B, Yang X, Sun Y, You MJ, Ma L. Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways. Cancer Research. PMID 27569213 DOI: 10.1158/0008-5472.Can-16-1571  0.301
2016 Liu X, Xiao ZD, Han L, Zhang J, Lee SW, Wang W, Lee H, Zhuang L, Chen J, Lin HK, Wang J, Liang H, Gan B. LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress. Nature Cell Biology. PMID 26999735 DOI: 10.1038/Ncb3328  0.404
2016 Hyemin L, Dai F, Zhuang L, Xiao ZD, Kim J, Zhang Y, Ma L, You MJ, Wang Z, Gan B. BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21. Oncotarget. PMID 26992241 DOI: 10.18632/Oncotarget.8102  0.454
2015 Wang W, Xiao ZD, Li X, Aziz KE, Gan B, Johnson RL, Chen J. AMPK modulates Hippo pathway activity to regulate energy homeostasis. Nature Cell Biology. 17: 490-9. PMID 25751139 DOI: 10.1038/Ncb3113  0.404
2014 Lin A, Piao HL, Zhuang L, Sarbassov dos D, Ma L, Gan B. FoxO transcription factors promote AKT Ser473 phosphorylation and renal tumor growth in response to pharmacologic inhibition of the PI3K-AKT pathway. Cancer Research. 74: 1682-93. PMID 24448243 DOI: 10.1158/0008-5472.Can-13-1729  0.439
2014 Lin A, Yao J, Zhuang L, Wang D, Han J, Lam EW, Gan B. The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress. Oncogene. 33: 3183-94. PMID 23851496 DOI: 10.1038/Onc.2013.273  0.432
2013 Hu J, Ho AL, Yuan L, Hu B, Hua S, Hwang SS, Zhang J, Hu T, Zheng H, Gan B, Wu G, Wang YA, Chin L, DePinho RA. From the Cover: Neutralization of terminal differentiation in gliomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 14520-7. PMID 23918370 DOI: 10.1073/Pnas.1308610110  0.415
2013 Keniry M, Pires MM, Mense S, Lefebvre C, Gan B, Justiano K, Lau YK, Hopkins B, Hodakoski C, Koujak S, Toole J, Fenton F, Calahan A, Califano A, DePinho RA, et al. Survival factor NFIL3 restricts FOXO-induced gene expression in cancer. Genes & Development. 27: 916-27. PMID 23630076 DOI: 10.1101/Gad.214049.113  0.399
2013 Rosborough BR, Raïch-Regué D, Matta BM, Lee K, Gan B, DePinho RA, Hackstein H, Boothby M, Turnquist HR, Thomson AW. Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction. Blood. 121: 3619-30. PMID 23444404 DOI: 10.1182/Blood-2012-08-448290  0.357
2012 Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, ... ... Gan B, et al. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell. 149: 656-70. PMID 22541435 DOI: 10.1016/J.Cell.2012.01.058  0.35
2012 Ding Z, Wu CJ, Jaskelioff M, Ivanova E, Kost-Alimova M, Protopopov A, Chu GC, Wang G, Lu X, Labrot ES, Hu J, Wang W, Xiao Y, Zhang H, Zhang J, ... ... Gan B, et al. Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases. Cell. 148: 896-907. PMID 22341455 DOI: 10.1016/J.Cell.2012.01.039  0.326
2012 Hu J, Hwang SS, Liesa M, Gan B, Sahin E, Jaskelioff M, Ding Z, Ying H, Boutin AT, Zhang H, Johnson S, Ivanova E, Kost-Alimova M, Protopopov A, Wang YA, et al. Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer. Cell. 148: 651-63. PMID 22341440 DOI: 10.1016/J.Cell.2011.12.028  0.367
2012 Zhang K, Li L, Qi Y, Zhu X, Gan B, DePinho RA, Averitt T, Guo S. Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice. Endocrinology. 153: 631-46. PMID 22147007 DOI: 10.1210/En.2011-1527  0.337
2012 Ying H, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik J, Lim C, Guimaraes AR, Kimmelman AC, Martin ES, Chang J, Hezel A, ... ... Gan B, et al. Abstract A101: Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A101  0.354
2011 Wei H, Wei S, Gan B, Peng X, Zou W, Guan JL. Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis. Genes & Development. 25: 1510-27. PMID 21764854 DOI: 10.1101/Gad.2051011  0.574
2011 Zhang Y, Gan B, Liu D, Paik JH. FoxO family members in cancer. Cancer Biology & Therapy. 12: 253-9. PMID 21613825 DOI: 10.4161/Cbt.12.4.15954  0.393
2010 Gan B, Hu J, Jiang S, Liu Y, Sahin E, Zhuang L, Fletcher-Sananikone E, Colla S, Wang YA, Chin L, Depinho RA. Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature. 468: 701-4. PMID 21124456 DOI: 10.1038/Nature09595  0.434
2010 Zheng H, Ying H, Wiedemeyer R, Yan H, Quayle SN, Ivanova EV, Paik JH, Zhang H, Xiao Y, Perry SR, Hu J, Vinjamoori A, Gan B, Sahin E, Chheda MG, et al. PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas. Cancer Cell. 17: 497-509. PMID 20478531 DOI: 10.1016/J.Ccr.2010.03.020  0.356
2010 Liang CC, Wang C, Peng X, Gan B, Guan JL. Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration. The Journal of Biological Chemistry. 285: 3499-509. PMID 19940130 DOI: 10.1074/Jbc.M109.072389  0.528
2009 Gan B, DePinho RA. mTORC1 signaling governs hematopoietic stem cell quiescence. Cell Cycle (Georgetown, Tex.). 8: 1003-6. PMID 19270523 DOI: 10.4161/Cc.8.7.8045  0.432
2009 Wei H, Gan B, Wu X, Guan JL. Inactivation of FIP200 leads to inflammatory skin disorder, but not tumorigenesis, in conditional knock-out mouse models. The Journal of Biological Chemistry. 284: 6004-13. PMID 19106106 DOI: 10.1074/Jbc.M806375200  0.642
2008 Gan B, Sahin E, Jiang S, Sanchez-Aguilera A, Scott KL, Chin L, Williams DA, Kwiatkowski DJ, DePinho RA. mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization. Proceedings of the National Academy of Sciences of the United States of America. 105: 19384-9. PMID 19052232 DOI: 10.1073/Pnas.0810584105  0.429
2008 Martin N, Schwamborn K, Urlaub H, Gan B, Guan JL, Dejean A. Spatial interplay between PIASy and FIP200 in the regulation of signal transduction and transcriptional activity. Molecular and Cellular Biology. 28: 2771-81. PMID 18285457 DOI: 10.1128/Mcb.01210-07  0.57
2008 Gan B, Guan JL. FIP200, a key signaling node to coordinately regulate various cellular processes. Cellular Signalling. 20: 787-94. PMID 18036779 DOI: 10.1016/J.Cellsig.2007.10.021  0.561
2007 Nagy T, Wei H, Shen TL, Peng X, Liang CC, Gan B, Guan JL. Mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland. The Journal of Biological Chemistry. 282: 31766-76. PMID 17716968 DOI: 10.1074/Jbc.M705403200  0.683
2006 Gan B, Yoo Y, Guan JL. Association of focal adhesion kinase with tuberous sclerosis complex 2 in the regulation of s6 kinase activation and cell growth. The Journal of Biological Chemistry. 281: 37321-9. PMID 17043358 DOI: 10.1074/Jbc.M605241200  0.608
2006 Gan B, Peng X, Nagy T, Alcaraz A, Gu H, Guan JL. Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways. The Journal of Cell Biology. 175: 121-33. PMID 17015619 DOI: 10.1083/Jcb.200604129  0.667
2006 Wei H, Wang X, Gan B, Urvalek AM, Melkoumian ZK, Guan JL, Zhao J. Sumoylation delimits KLF8 transcriptional activity associated with the cell cycle regulation. The Journal of Biological Chemistry. 281: 16664-71. PMID 16617055 DOI: 10.1074/Jbc.M513135200  0.54
2005 Melkoumian ZK, Peng X, Gan B, Wu X, Guan JL. Mechanism of cell cycle regulation by FIP200 in human breast cancer cells. Cancer Research. 65: 6676-84. PMID 16061648 DOI: 10.1158/0008-5472.Can-04-4142  0.641
2005 Wu X, Gan B, Yoo Y, Guan JL. FAK-mediated src phosphorylation of endophilin A2 inhibits endocytosis of MT1-MMP and promotes ECM degradation. Developmental Cell. 9: 185-96. PMID 16054026 DOI: 10.1016/J.Devcel.2005.06.006  0.61
2005 Gan B, Melkoumian ZK, Wu X, Guan KL, Guan JL. Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control. The Journal of Cell Biology. 170: 379-89. PMID 16043512 DOI: 10.1083/Jcb.200411106  0.65
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