| Year |
Citation |
Score |
| 2016 |
Potluri P, Procaccio V, Scheffler IE, Wallace DC. High throughput gene complementation screening permits identification of a mammalian mitochondrial protein synthesis (ρ(-)) mutant. Biochimica Et Biophysica Acta. PMID 26946086 DOI: 10.1016/J.Bbabio.2016.02.021 |
0.397 |
|
| 2015 |
Scheffler IE. Mitochondrial disease associated with complex I (NADH-CoQ oxidoreductase) deficiency. Journal of Inherited Metabolic Disease. 38: 405-15. PMID 25224827 DOI: 10.1007/S10545-014-9768-6 |
0.347 |
|
| 2012 |
Lau E, Kluger H, Varsano T, Lee K, Scheffler I, Rimm DL, Ideker T, Ronai ZA. PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria. Cell. 148: 543-55. PMID 22304920 DOI: 10.1016/J.Cell.2012.01.016 |
0.303 |
|
| 2012 |
Potluri P, Scheffler IE, Wallace DC. Characterization of a Chinese hamster mutant cell line with a complete defect in mitochondrial protein synthesis Mitochondrion. 12: 577-578. DOI: 10.1016/J.Mito.2012.07.070 |
0.363 |
|
| 2011 |
Compton S, Kim C, Griner NB, Potluri P, Scheffler IE, Sen S, Jerry DJ, Schneider S, Yadava N. Mitochondrial dysfunction impairs tumor suppressor p53 expression/function. The Journal of Biological Chemistry. 286: 20297-312. PMID 21502317 DOI: 10.1074/Jbc.M110.163063 |
0.357 |
|
| 2010 |
Scheffler IE. Assembling complex I with ACAD9. Cell Metabolism. 12: 211-2. PMID 20816087 DOI: 10.1016/J.Cmet.2010.08.008 |
0.317 |
|
| 2010 |
Fogal V, Richardson AD, Karmali PP, Scheffler IE, Smith JW, Ruoslahti E. Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation. Molecular and Cellular Biology. 30: 1303-18. PMID 20100866 DOI: 10.1128/Mcb.01101-09 |
0.358 |
|
| 2009 |
Potluri P, Davila A, Ruiz-Pesini E, Mishmar D, O'Hearn S, Hancock S, Simon M, Scheffler IE, Wallace DC, Procaccio V. A novel NDUFA1 mutation leads to a progressive mitochondrial complex I-specific neurodegenerative disease. Molecular Genetics and Metabolism. 96: 189-95. PMID 19185523 DOI: 10.1016/J.Ymgme.2008.12.004 |
0.343 |
|
| 2007 |
Yadava N, Potluri P, Scheffler IE. Investigations of the potential effects of phosphorylation of the MWFE and ESSS subunits on complex I activity and assembly. The International Journal of Biochemistry & Cell Biology. 40: 447-60. PMID 17931954 DOI: 10.1016/J.Biocel.2007.08.015 |
0.346 |
|
| 2004 |
Yadava N, Scheffler IE. Import and orientation of the MWFE protein in mitochondrial NADH-ubiquinone oxidoreductase. Mitochondrion. 4: 1-12. PMID 16120368 DOI: 10.1016/J.Mito.2004.04.002 |
0.304 |
|
| 2004 |
Scheffler IE, Yadava N, Potluri P. Molecular genetics of complex I-deficient Chinese hamster cell lines. Biochimica Et Biophysica Acta. 1659: 160-71. PMID 15576048 DOI: 10.1016/J.Bbabio.2004.08.002 |
0.381 |
|
| 2004 |
Potluri P, Yadava N, Scheffler IE. The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase). European Journal of Biochemistry / Febs. 271: 3265-73. PMID 15265046 DOI: 10.1111/J.1432-1033.2004.04260.X |
0.374 |
|
| 2004 |
Ricci JE, Muñoz-Pinedo C, Fitzgerald P, Bailly-Maitre B, Perkins GA, Yadava N, Scheffler IE, Ellisman MH, Green DR. Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain. Cell. 117: 773-86. PMID 15186778 DOI: 10.1016/J.Cell.2004.05.008 |
0.321 |
|
| 2004 |
Yadava N, Houchens T, Potluri P, Scheffler IE. Development and characterization of a conditional mitochondrial complex I assembly system. The Journal of Biological Chemistry. 279: 12406-13. PMID 14722084 DOI: 10.1074/Jbc.M313588200 |
0.392 |
|
| 2003 |
Wong EA, Scheffler IE. Temperature-sensitive Chinese hamster fibroblast mutant with a defect in RNA metabolism. Molecular and Cellular Biology. 2: 1558-73. PMID 14582197 DOI: 10.1128/Mcb.2.12.1558 |
0.398 |
|
| 2003 |
Albayrak T, Scherhammer V, Schoenfeld N, Braziulis E, Mund T, Bauer MK, Scheffler IE, Grimm S. The tumor suppressor cybL, a component of the respiratory chain, mediates apoptosis induction. Molecular Biology of the Cell. 14: 3082-96. PMID 12925748 DOI: 10.1091/Mbc.E02-10-0631 |
0.316 |
|
| 2002 |
de la Cruz BJ, Prieto S, Scheffler IE. The role of the 5' untranslated region (UTR) in glucose-dependent mRNA decay. Yeast (Chichester, England). 19: 887-902. PMID 12112242 DOI: 10.1002/Yea.884 |
0.722 |
|
| 2002 |
Yadava N, Potluri P, Smith EN, Bisevac A, Scheffler IE. Species-specific and mutant MWFE proteins. Their effect on the assembly of a functional mammalian mitochondrial complex I. The Journal of Biological Chemistry. 277: 21221-30. PMID 11937507 DOI: 10.1074/Jbc.M202016200 |
0.352 |
|
| 2002 |
Scheffler IE, Yadava N. Molecular genetics of the mammalian NADH-ubiquinone oxidoreductase. Journal of Bioenergetics and Biomembranes. 33: 243-50. PMID 11695834 DOI: 10.1023/A:1010739120891 |
0.374 |
|
| 2001 |
Scheffler IE. Mitochondria make a come back. Advanced Drug Delivery Reviews. 49: 3-26. PMID 11377800 DOI: 10.1016/S0169-409X(01)00123-5 |
0.325 |
|
| 2001 |
Lin KM, Lin B, Lian IY, Mestril R, Scheffler IE, Dillmann WH. Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation Circulation. 103: 1787-1792. PMID 11282911 DOI: 10.1161/01.Cir.103.13.1787 |
0.306 |
|
| 2000 |
Prieto S, de la Cruz BJ, Scheffler IE. Glucose-regulated turnover of mRNA and the influence of poly(A) tail length on half-life. The Journal of Biological Chemistry. 275: 14155-66. PMID 10799492 DOI: 10.1074/Jbc.275.19.14155 |
0.727 |
|
| 1999 |
Au HC, Seo BB, Matsuno-Yagi A, Yagi T, Scheffler IE. The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 96: 4354-9. PMID 10200266 DOI: 10.1073/Pnas.96.8.4354 |
0.379 |
|
| 1998 |
Scheffler IE, de la Cruz BJ, Prieto S. Control of mRNA turnover as a mechanism of glucose repression in Saccharomyces cerevisiae. The International Journal of Biochemistry & Cell Biology. 30: 1175-93. PMID 9839444 DOI: 10.1128/Mcb.12.7.2941 |
0.731 |
|
| 1998 |
Elbehti-Green A, Au HC, Mascarello JT, Ream-Robinson D, Scheffler IE. Characterization of the human SDHC gene encoding of the integral membrane proteins of succinate-quinone oxidoreductase in mitochondria. Gene. 213: 133-40. PMID 9714607 DOI: 10.1016/S0378-1119(98)00186-3 |
0.365 |
|
| 1998 |
Seo BB, Kitajima-Ihara T, Chan EK, Scheffler IE, Matsuno-Yagi A, Yagi T. Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 9167-71. PMID 9689052 DOI: 10.1073/Pnas.95.16.9167 |
0.442 |
|
| 1998 |
Scheffler IE. Molecular genetics of succinate:quinone oxidoreductase in eukaryotes. Progress in Nucleic Acid Research and Molecular Biology. 60: 267-315. PMID 9594577 DOI: 10.1016/S0079-6603(08)60895-8 |
0.37 |
|
| 1998 |
Au HC, Scheffler IE. Promoter analysis of the human succinate dehydrogenase iron-protein gene--both nuclear respiratory factors NRF-1 and NRF-2 are required. European Journal of Biochemistry. 251: 164-74. PMID 9492280 DOI: 10.1046/J.1432-1327.1998.2510164.X |
0.388 |
|
| 1997 |
Lorenzini EC, Scheffler IE. Co-operation of the 5' and 3' untranslated regions of ornithine decarboxylase mRNA and inhibitory role of its 3' untranslated region in regulating the translational efficiency of hybrid RNA species via cellular factor. The Biochemical Journal. 361-7. PMID 9291106 DOI: 10.1042/Bj3260361 |
0.437 |
|
| 1997 |
Au HC, Scheffler IE. A respiration-deficient Chinese hamster cell line with a defect in mitochondrial protein synthesis: rapid turnover of some mitochondrial transcripts. Somatic Cell and Molecular Genetics. 23: 27-35. PMID 9217999 DOI: 10.1007/Bf02679953 |
0.458 |
|
| 1996 |
Cereghino GP, Atencio DP, Saghbini M, Beiner J, Scheffler IE. Glucose-dependent turnover of the mRNAs encoding succinate dehydrogenase peptides in Saccharomyces cerevisiae: sequence elements in the 5' untranslated region of the Ip mRNA play a dominant role. Molecular Biology of the Cell. 6: 1125-43. PMID 8534911 DOI: 10.1091/Mbc.6.9.1125 |
0.553 |
|
| 1996 |
Cereghino GP, Scheffler IE. Genetic analysis of glucose regulation in saccharomyces cerevisiae: control of transcription versus mRNA turnover. The Embo Journal. 15: 363-374. DOI: 10.1002/J.1460-2075.1996.Tb00366.X |
0.544 |
|
| 1995 |
Au HC, Ream-Robinson D, Bellew LA, Broomfield PL, Saghbini M, Scheffler IE. Structural organization of the gene encoding the human iron-sulfur subunit of succinate dehydrogenase. Gene. 159: 249-53. PMID 7622059 DOI: 10.1016/0378-1119(95)00162-Y |
0.37 |
|
| 1995 |
Oostveen FG, Au HC, Meijer PJ, Scheffler IE. A Chinese hamster mutant cell line with a defect in the integral membrane protein CII-3 of complex II of the mitochondrial electron transport chain. The Journal of Biological Chemistry. 270: 26104-8. PMID 7592812 DOI: 10.1074/Jbc.270.44.26104 |
0.396 |
|
| 1995 |
Lovkvist-Wallstrom E, Stjernborg-Ulvsback L, Scheffler IE, Persson L. Regulation of mammalian ornithine decarboxylase. Studies on the induction of the enzyme by hypotonic stress. Febs Journal. 231: 40-44. DOI: 10.1111/J.1432-1033.1995.Tb20667.X |
0.441 |
|
| 1995 |
Lövkvist‐Wallström E, Stjernborg‐Ulvsbäck L, Scheffler IE, Persson L. Regulation of Mammalian Ornithine Decarboxylase Febs Journal. 231: 40-44. DOI: 10.1111/J.1432-1033.1995.0040F.X |
0.453 |
|
| 1994 |
Au HC, Scheffler IE. Characterization of the gene encoding the iron-sulfur protein subunit of succinate dehydrogenase from Drosophila melanogaster. Gene. 149: 261-5. PMID 7958999 DOI: 10.1016/0378-1119(94)90158-9 |
0.384 |
|
| 1992 |
Schmidt DM, Saghbini M, Scheffler IE. The C-terminus of the succinate dehydrogenase IP peptide of Saccharomyces cerevisiae is significant for assembly of complex II. Biochemistry. 31: 8442-8. PMID 1390628 DOI: 10.1021/Bi00151A008 |
0.316 |
|
| 1989 |
Gould SJ, Subramani S, Scheffler IE. Use of the DNA polymerase chain reaction for homology probing: isolation of partial cDNA or genomic clones encoding the iron-sulfur protein of succinate dehydrogenase from several species. Proceedings of the National Academy of Sciences of the United States of America. 86: 1934-8. PMID 2494655 DOI: 10.1073/Pnas.86.6.1934 |
0.317 |
|
| 1988 |
Feige JJ, Keller GA, Scheffler IE. Temperature-sensitive Chinese hamster cell mutant with a defect in glycoprotein synthesis: accumulation of the EGF receptor in the endoplasmic reticulum and the role of the glucose-regulated protein GRP78. Journal of Cellular Physiology. 136: 33-42. PMID 3294237 DOI: 10.1002/Jcp.1041360105 |
0.354 |
|
| 1988 |
Feige JJ, Scheffler IE. Analysis of the protein glycosylation defect of a temperature-sensitive cell cycle mutant by the use of mutant cells overexpressing the human epidermal growth factor receptor after transfection of the gene. Journal of Cellular Physiology. 133: 461-70. PMID 3121640 DOI: 10.1002/Jcp.1041330306 |
0.373 |
|
| 1988 |
Slezynger TC, Scheffler IE. Steady-state and nuclear run-on analyses of transcription in a temperature-sensitive Chinese hamster cell mutant with a defect in RNA metabolism. Somatic Cell and Molecular Genetics. 14: 439-59. PMID 2459782 DOI: 10.1007/Bf01534711 |
0.364 |
|
| 1987 |
Lee AS, Wells S, Kim KS, Scheffler IE. Enhanced synthesis of the glucose/calcium-regulated proteins in a hamster cell mutant deficient in transfer of oligosaccharide core to polypeptides. Journal of Cellular Physiology. 129: 277-82. PMID 3782307 DOI: 10.1002/Jcp.1041290302 |
0.449 |
|
| 1986 |
Dircks L, Grens A, Slezynger TC, Scheffler IE. Posttranscriptional regulation of ornithine decarboxylase activity. Journal of Cellular Physiology. 126: 371-8. PMID 3081524 DOI: 10.1002/Jcp.1041260307 |
0.411 |
|
| 1985 |
Steglich C, Grens A, Scheffler IE. Chinese hamster cells deficient in ornithine decarboxylase activity: reversion by gene amplification and by azacytidine treatment. Somatic Cell and Molecular Genetics. 11: 11-23. PMID 2579446 DOI: 10.1007/Bf01534730 |
0.345 |
|
| 1983 |
Day CE, Scheffler IE. Mapping of the genes of some components of the electron transport chain (complex I) on the X chromosome of mammals. Somatic Cell Genetics. 8: 691-707. PMID 6819642 DOI: 10.1007/Bf01543012 |
0.329 |
|
| 1981 |
Landy-Otsuka F, Scheffler IE. Enzyme induction in a temperature-sensitive cell cycle mutant of Chinese hamster fibroblasts. Journal of Cellular Physiology. 105: 209-20. PMID 7462327 DOI: 10.1002/Jcp.1041050204 |
0.32 |
|
| 1981 |
Schlosser CA, Steglich C, deWet JR, Scheffler IE. Cell cycle-dependent regulation of thymidine kinase activity introduced into mouse LMTK- cells by DNA and chromatin-mediated gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 78: 1119-23. PMID 6940130 DOI: 10.1073/Pnas.78.2.1119 |
0.331 |
|
| 1981 |
Mascarello JT, Soderberg K, Scheffler IE. Assignment of a gene for succinate dehydrogenase to human chromosome 1 by somatic cell hybridization. Cytogenetics and Cell Genetics. 28: 121-35. PMID 6934864 DOI: 10.1159/000131520 |
0.309 |
|
| 1981 |
Choi J, Scheffler IE. A mutant of Chinese hamster ovary cells resistant to alpha-methyl- and alpha-difluoromethylornithine. Somatic Cell Genetics. 7: 219-33. PMID 6794163 DOI: 10.1007/Bf01567659 |
0.329 |
|
| 1981 |
Burnett KG, Scheffler IE. Integrity of mitochondria in a mammalian cell mutant defective in mitochondrial protein synthesis. The Journal of Cell Biology. 90: 108-15. PMID 6265473 DOI: 10.1083/Jcb.90.1.108 |
0.371 |
|
| 1980 |
Breen GA, Scheffler IE. Cytoplasmic inheritance of oligomycin resistance in Chinese hamster ovary cells. The Journal of Cell Biology. 86: 723-9. PMID 6447704 DOI: 10.1083/Jcb.86.3.723 |
0.308 |
|
| 1979 |
Breen GA, Scheffler IE. Respiration-deficient Chinese hamster cell mutants: biochemical characterization. Somatic Cell Genetics. 5: 441-51. PMID 494059 DOI: 10.1007/Bf01538879 |
0.309 |
|
| 1979 |
Soderberg K, Mascarello JT, Breen GA, Scheffler IE. Respiration-deficient Chinese hamster cell mutants: genetic characterization. Somatic Cell Genetics. 5: 225-40. PMID 483122 DOI: 10.1007/Bf01539163 |
0.344 |
|
| 1979 |
Landy-Otsuka F, Scheffler IE. Induction of ornithine decarboxylase activity in a temperature-sensitive cell cycle mutant of Chinese hamster cells. Proceedings of the National Academy of Sciences of the United States of America. 75: 5001-5. PMID 283409 DOI: 10.1073/Pnas.75.10.5001 |
0.397 |
|
| 1979 |
Tenner AJ, Scheffler IE. Lipid‐saccharide intermediates and glycoprotein biosynthesis in a temperature‐sensitive Chinese hamster cell mutant Journal of Cellular Physiology. 98: 251-265. PMID 217883 DOI: 10.1002/Jcp.1040980202 |
0.358 |
|
| 1977 |
Ditta G, Soderberg K, Landy F, Scheffler IE. The selection of Chinese hamster cells deficient in oxidative energy metabolism. Somatic Cell Genetics. 2: 331-44. PMID 1027147 DOI: 10.1007/Bf01538838 |
0.36 |
|
| 1977 |
Soderberg KL, Ditta GS, Scheffler IE. Mammalian cells with defective mitochondrial functions: a Chinese hamster mutant cell line lacking succinate dehydrogenase activity. Cell. 10: 697-702. PMID 558831 DOI: 10.1016/0092-8674(77)90103-9 |
0.399 |
|
| 1977 |
Tenner A, Zieg J, Scheffler IE. Glycoprotein synthesis in a temperature-sensitive Chinese hamster cell cycle mutant. Journal of Cellular Physiology. 90: 145-60. PMID 557044 DOI: 10.1002/Jcp.1040900202 |
0.353 |
|
| 1977 |
Ditta G, Soderberg K, Scheffler IE. Chinese hamster cell mutant with defective mitochondrial protein synthesis. Nature. 268: 64-67. PMID 196202 DOI: 10.1038/268064A0 |
0.356 |
|
| 1976 |
Donnelly M, Scheffler IE. Energy metabolism in respiration-deficient and wild type Chinese hamster fibroblasts in culture. Journal of Cellular Physiology. 89: 39-51. PMID 8468 DOI: 10.1002/Jcp.1040890105 |
0.373 |
|
| 1975 |
DeFrancesco L, Werntz D, Scheffler IE. Conditionally lethal mutations in chinese hamster cells. Characterization of a cell line with a possible defect in the Krebs cycle. Journal of Cellular Physiology. 85: 293-305. PMID 1123408 DOI: 10.1002/Jcp.1040850216 |
0.357 |
|
| 1974 |
Scheffler IE. Conditional lethal mutants of Chinese hamster cells: mutants requiring exogenous carbondioxide for growth. Journal of Cellular Physiology. 83: 219-30. PMID 4822527 DOI: 10.1002/Jcp.1040830208 |
0.334 |
|
| 1973 |
Scheffler IE, Buttin G. Conditionally lethal mutations in Chinese hamster cells. I. Isolation of a temperature-sensitive line and its investigation by cell cycle studies. Journal of Cellular Physiology. 81: 199-216. PMID 4348554 DOI: 10.1002/Jcp.1040810208 |
0.306 |
|
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