Shang-Ning Chien, Ph.D. - Publications

Affiliations: 
2011 Paper and Bioprocess Engineering State University of New York College of Environmental Science and Forestry 
Area:
Wood Technology Agriculture, Polymer Chemistry, General Chemistry

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhou Z, Wu Q, Yan Z, Zheng H, Chen CJ, Liu Y, Qi Z, Calandrelli R, Chen Z, Chien S, Su HI, Zhong S. Extracellular RNA in a single droplet of human serum reflects physiologic and disease states. Proceedings of the National Academy of Sciences of the United States of America. PMID 31481608 DOI: 10.1073/pnas.1908252116  0.48
2019 He M, Huang TS, Li S, Hong HC, Chen Z, Martin M, Zhou X, Huang HY, Su SH, Zhang J, Wang WT, Kang J, Huang HD, Zhang J, Chien S, et al. Atheroprotective Flow Upregulates ITPR3 (Inositol 1,4,5-Trisphosphate Receptor 3) in Vascular Endothelium via KLF4 (Krüppel-Like Factor 4)-Mediated Histone Modifications. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA118312301. PMID 30917677 DOI: 10.1161/ATVBAHA.118.312301  0.48
2019 Yeh YT, Wei J, Thorossian S, Nguyen K, Hoffman C, Del Álamo JC, Serrano R, Li YJ, Wang KC, Chien S. MiR-145 mediates cell morphology-regulated mesenchymal stem cell differentiation to smooth muscle cells. Biomaterials. 204: 59-69. PMID 30884320 DOI: 10.1016/j.biomaterials.2019.03.003  0.32
2019 Yan Z, Huang N, Wu W, Chen W, Jiang Y, Chen J, Huang X, Wen X, Xu J, Jin Q, Zhang K, Chen Z, Chien S, Zhong S. Genome-wide colocalization of RNA-DNA interactions and fusion RNA pairs. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718424 DOI: 10.1073/pnas.1819788116  0.48
2018 Lin FM, Chien S, Chen Z. Epigenetic profiling with ultralow DNA amounts. Nature Biomedical Engineering. 2: 146-147. PMID 31015721 DOI: 10.1038/s41551-018-0211-4  0.48
2018 Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, ... ... Chien S, et al. RAP2 mediates mechanoresponses of the Hippo pathway. Nature. PMID 30135582 DOI: 10.1038/s41586-018-0444-0  0.32
2018 Miao Y, Ajami NE, Huang TS, Lin FM, Lou CH, Wang YT, Li S, Kang J, Munkacsi H, Maurya MR, Gupta S, Chien S, Subramaniam S, Chen Z. Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function. Nature Communications. 9: 292. PMID 29348663 DOI: 10.1038/s41467-017-02113-y  0.48
2017 Yeh YT, Serrano R, François J, Chiu JJ, Li YJ, Del Álamo JC, Chien S, Lasheras JC. Three-dimensional forces exerted by leukocytes and vascular endothelial cells dynamically facilitate diapedesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29255056 DOI: 10.1073/pnas.1717489115  0.32
2017 Ajami NE, Gupta S, Maurya MR, Nguyen P, Li JY, Shyy JY, Chen Z, Chien S, Subramaniam S. Systems biology analysis of longitudinal functional response of endothelial cells to shear stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973892 DOI: 10.1073/pnas.1707517114  0.48
2017 Zhu JJ, Liu YF, Zhang YP, Zhao CR, Yao WJ, Li YS, Wang KC, Huang TS, Pang W, Wang XF, Wang X, Chien S, Zhou J. VAMP3 and SNAP23 mediate the disturbed flow-induced endothelial microRNA secretion and smooth muscle hyperplasia. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716920 DOI: 10.1073/pnas.1700561114  0.32
2017 Shang F, Wang SC, Hsu CY, Miao Y, Martin M, Yin Y, Wu CC, Wang YT, Wu G, Chien S, Huang HD, Tarng DC, Shiu YT, Cheung AK, Huang PH, et al. MicroRNA-92a Mediates Endothelial Dysfunction in CKD. Journal of the American Society of Nephrology : Jasn. PMID 28696247 DOI: 10.1681/ASN.2016111215  0.48
2017 Huang TS, Wang KC, Quon S, Nguyen P, Chang TY, Chen Z, Li YS, Subramaniam S, Shyy JY, Chien S. LINC00341 exerts an anti-inflammatory effect on endothelial cells by repressing VCAM1. Physiological Genomics. physiolgenomics.0013. PMID 28500253 DOI: 10.1152/physiolgenomics.00132.2016  0.48
2017 Chen Z, Li S, Subramaniam S, Shyy JY, Chien S. Epigenetic Regulation: A New Frontier for Biomedical Engineers. Annual Review of Biomedical Engineering. PMID 28301736 DOI: 10.1146/annurev-bioeng-071516-044720  0.48
2016 Lin TY, Wei TW, Li S, Wang SC, He M, Martin M, Zhang J, Shentu TP, Xiao H, Kang J, Wang KC, Chen Z, Chien S, Tsai MD, Shyy JY. TIFA as a crucial mediator for NLRP3 inflammasome. Proceedings of the National Academy of Sciences of the United States of America. PMID 27965388 DOI: 10.1073/pnas.1618773114  0.48
2016 Wang KC, Yeh YT, Nguyen P, Limqueco E, Lopez J, Thorossian S, Guan KL, Li YJ, Chien S. Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27671657 DOI: 10.1073/pnas.1613121113  0.32
2016 Wu Y, Zhang K, Seong J, Fan J, Chien S, Wang Y, Lu S. In-situ coupling between kinase activities and protein dynamics within single focal adhesions. Scientific Reports. 6: 29377. PMID 27383747 DOI: 10.1038/srep29377  0.32
2016 Qi YX, Yao QP, Huang K, Shi Q, Zhang P, Wang GL, Han Y, Bao H, Wang L, Li HP, Shen BR, Wang Y, Chien S, Jiang ZL. Nuclear envelope proteins modulate proliferation of vascular smooth muscle cells during cyclic stretch application. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114541 DOI: 10.1073/pnas.1604569113  0.32
2016 Ma X, Qu X, Zhu W, Li YS, Yuan S, Zhang H, Liu J, Wang P, Lai CS, Zanella F, Feng GS, Sheikh F, Chien S, Chen S. Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858399 DOI: 10.1073/pnas.1524510113  0.32
2016 Du J, Zu Y, Li J, Du S, Xu Y, Zhang L, Jiang L, Wang Z, Chien S, Yang C. Extracellular matrix stiffness dictates Wnt expression through integrin pathway. Scientific Reports. 6: 20395. PMID 26854061 DOI: 10.1038/srep20395  0.32
2013 Butler PJ, Chien S. Role of the plasma membrane in endothelial cell mechanosensation of shear stress Cellular Mechanotransduction: Diverse Perspectives From Molecules to Tissues. 61-88. DOI: 10.1017/CBO9781139195874.004  0.32
2012 Chien S. UCSDs institute of engineering in medicine: Fostering collaboration through research and education Ieee Pulse. 3: 35-41. PMID 22850836 DOI: 10.1109/MPUL.2012.2196835  0.32
2011 Chien S. A brief history of the bioengineering institute of California and the UC system-wide symposia Annals of Biomedical Engineering. 39: 1156-1162. PMID 21384235 DOI: 10.1007/s10439-011-0288-3  0.32
2011 Chiu JJ, Chien S. Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives. Physiological Reviews. 91: 327-87. PMID 21248169 DOI: 10.1152/physrev.00047.2009  0.32
2011 Chien S. Mechanotransduction in endothelial cells studied with fluorescence imaging Journal of Physics: Conference Series. 277. DOI: 10.1088/1742-6596/277/1/012001  0.32
2009 Chien S. Role of mechanical forces in endothelial homeostasis Proceedings of the Asme Summer Bioengineering Conference, Sbc2008. 65-66.  0.32
2008 Chien S. Role of shear stress direction in endothelial mechanotransduction McB Molecular and Cellular Biomechanics. 5: 1-8. PMID 18524241  0.32
2008 Chien S. Effects of disturbed flow on endothelial cells Annals of Biomedical Engineering. 36: 554-562. PMID 18172767 DOI: 10.1007/s10439-007-9426-3  0.32
2007 Wang Y, Chien S. Analysis of integrin signaling by fluorescence resonance energy transfer. Methods in Enzymology. 426: 177-201. PMID 17697885 DOI: 10.1016/S0076-6879(07)26009-4  0.32
2007 Chien S. Mechanotransduction and endothelial cell homeostasis: The wisdom of the cell American Journal of Physiology - Heart and Circulatory Physiology. 292. PMID 17098825 DOI: 10.1152/ajpheart.01047.2006  0.32
2007 Chien S. Role of stress direction on mechanotransduction and functions of endothelial cells Beijing Daxue Xuebao (Ziran Kexue Ban)/Acta Scientiarum Naturalium Universitatis Pekinensis. 43: 435-440.  0.32
2006 Chien S. Molecular basis of rheological modulation of endothelial functions: Importance of stress direction Biorheology. 43: 95-116. PMID 16687781 DOI: 10.1016/j.cca.2006.01.017  0.32
2006 Chien S. Mechanical and chemical regulation of endothelial cell polarity Circulation Research. 98: 863-865. PMID 16614310 DOI: 10.1161/01.RES.0000219686.29872.e2  0.32
2004 Chien S. The National Institute of Biomedical Imaging and Bioengineering Annual Review of Biomedical Engineering. 6: 1-26. PMID 15255760 DOI: 10.1146/annurev.bioeng.6.062403.131947  0.32
2003 Chien S. XXXV International Congress of Physiological Sciences (IUPS Congress 2005) News in Physiological Sciences. 18: 179-180. PMID 12869620  0.32
2003 Chien S. Molecular and mechanical bases of focal lipid accumulation in arterial wall Progress in Biophysics and Molecular Biology. 83: 131-151. PMID 12865076 DOI: 10.1016/S0079-6107(03)00053-1  0.32
2001 Chien S, Maynard CD. Newest member of the NIH family [2] Science. 291: 1701-1702. PMID 11249810  0.32
1999 Chien S, Shyy JYJ. Effects of shear stress on gene expression and signal transduction in endothelial cells American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 42: 613-614.  0.32
1998 Chien S, Shyy JYJ. Effects of hemodynamic forces on gene expression and signal transduction in endothelial cells Biological Bulletin. 194: 390-393. PMID 9664671  0.32
1993 Chien S. Let our voices be heard and amplified. The time is now! Faseb Journal. 7: 615-616. PMID 8500685  0.32
1993 Weinbaum S, Chien S. Lipid transport aspects of atherogenesis Journal of Biomechanical Engineering. 115: 602-610. PMID 8302048  0.32
1993 Chien S, Silverstein SC. Economic impact of applications of monoclonal antibodies to medicine and biology Faseb Journal. 7: 1426-1431. PMID 8262326  0.32
1992 Chien S. The Benjamin W. Zweifach award lecture. Blood cell deformability and interactions: From molecules to micromechanics and microcirculation Microvascular Research. 44: 243-254. PMID 1479926 DOI: 10.1016/0026-2862(92)90084-3  0.32
1990 Chien S, Sung LP. Molecular basis of red cell membrane rheology. Part 1 Biorheology. 27: 327-344. PMID 2261500  0.32
1989 Kaperonis AA, Chien S. Effects of Centrifugation on Transmembrane Water Loss from Normal and Pathologic Erythrocytes Proceedings of the Society For Experimental Biology and Medicine. 190: 174-178. PMID 2644654 DOI: 10.3181/00379727-190-42846  0.32
1989 Lipowsky HH, Chien S. Role of leukocyte-endothelium adhesion in affecting recovery from ischemic episodes Annals of the New York Academy of Sciences. 565: 308-315. PMID 2476065 DOI: 10.1111/j.1749-6632.1989.tb24178.x  0.32
1989 Schmalzer EA, Chien S. Effect of methylxanthines, cytochalasin B and FMLP on neutrophil filterability in a constant flow system Clinical Hemorheology. 9: 69-80.  0.32
1988 Kaperonis AA, Chien S. Blood rheology and red cell metabolism in the menstrual cycle in normal and heterozygous thalassemic women Clinical Hemorheology. 8: 751-762.  0.32
1987 Chien S. Red cell deformability and its relevance to blood flow Annual Review of Physiology. 177-192. PMID 3551796  0.32
1987 Reinhart WH, Chien S. The time course of filtration test as a model for microvascular plugging by white cells and hardened red cells Microvascular Research. 34: 1-12. PMID 3116369 DOI: 10.1016/0026-2862(87)90075-6  0.32
1987 Chien S, Gargus JJ. Molecular biology in physiology Faseb Journal. 1: 97-102. PMID 2886391  0.32
1987 Chien S. Molecular biology in biorheology Biorheology. 24: 659-672. PMID 2458776  0.32
1987 Reinhart WH, Chien S. Echinocyte-stomatocyte transformation and shape control of human red blood cells: Morphological aspects American Journal of Hematology. 24: 1-14. PMID 2432778  0.32
1986 Chien S. Blood rheology in myocardial infarction and hypertension Biorheology. 23: 633-653. PMID 3307943  0.32
1985 Schmukler R, Chien S. Rapid deoxygenation of red cells and hemoglobin solution using hollow capillary fibers Biorheology. 22: 21-29. PMID 3986316  0.32
1985 Chien S. The microcirculatory society Eugene M. Landis award lecture. Role of blood cells in microcirculatory regulation Microvascular Research. 29. PMID 3887106 DOI: 10.1016/0026-2862(85)90012-3  0.32
1985 Chien S. Hemodynamics of the dental pulp Journal of Dental Research. 64: 602-606. PMID 3857262  0.32
1985 Tozeren A, Chien S. Modeling of time-variant coupling between left ventricle and aorta in cardiac cycle American Journal of Physiology - Heart and Circulatory Physiology. 18.  0.32
1984 Schmalzer EA, Chien S. Filterability of subpopulations of leukocytes: Effects of pentoxifylline Blood. 64: 542-546. PMID 6743827  0.32
1984 Chien S. Rheology of sickle cells and the microcirculation New England Journal of Medicine. 311: 1567-1569. PMID 6504084  0.32
1984 Reinhart WH, Chien S. Influence of cell shape on red cell filterability Federation Proceedings. 43.  0.32
1983 Skalak R, Chien S. Theoretical models of rouleau formation and disaggregation. Annals of the New York Academy of Sciences. 416: 138-48. PMID 6587806  0.32
1983 Handley DA, Chien S. Colloidal Gold: A Pluripotent Receptor Probe (41697) Proceedings of the Society For Experimental Biology and Medicine. 174: 1-11. PMID 6356133 DOI: 10.3181/00379727-174-41697  0.32
1983 Simchon S, Chien S. Effects of variations in renal hemodynamics on the time course of renin secretion rate American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 14.  0.32
1982 Chien S. Rheology in the microcirculation in normal and low flow states Advances in Shock Research. 8: 71-80. PMID 7136948  0.32
1982 Skalak R, Chien S. Rheology of blood cells as soft tissues. Biorheology. 19: 453-61. PMID 7104483  0.32
1982 Chien S. Hemorheology in clinical medicine Clinical Hemorheology. 2: 137-142.  0.32
1982 Simchon S, Chien S. A new method for kidney perfusion in situ: Application to dynamics of autoregulation American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 11.  0.32
1981 Skalak R, Chien S. Capillary flow: history, experiments and theory. Biorheology. 18: 307-30. PMID 7034803  0.32
1981 Chien S. Filterability and other methods of approaching red cell deformability. Determinants of blood viscosity and red cell deformability Scandinavian Journal of Clinical and Laboratory Investigation, Supplement. 156: 7-12. PMID 6948403  0.32
1981 Handley DA, Chien S. Oxidation of ruthenium red for use as an intercellular tracer Histochemistry. 71: 249-258. PMID 6165705 DOI: 10.1007/BF00507828  0.32
1981 Chien S. Determinants of blood viscosity and red cell deformability Scandinavian Journal of Clinical and Laboratory Investigation. 41: 7-12. DOI: 10.3109/00365518109097424  0.32
1981 Chien S. Haemorheology in disease: Pathophysiological significance and therapeutic implications Clinical Hemorheology. 1: 419-442.  0.32
1979 Lee MML, Chien S. Morphologic effects of pressure changes on canine carotid artery endothelium as observed by scanning electron microscopy Anatomical Record. 194: 1-14. PMID 443557  0.32
1978 Chien S. Interactions between red cell membranes Bioelectrochemistry and Bioenergetics. 5: 317. DOI: 10.1016/0302-4598(87)87043-5  0.32
1978 Chen RYZ, Chien S. Hemodynamic functions and blood viscosity in surface hypothermia American Journal of Physiology - Heart and Circulatory Physiology. 4.  0.32
1977 Chen RY, Chien S. Plasma volume, red cell volume, and thoracic duct lymph flow in hypothermia The American Journal of Physiology. 233. PMID 920823  0.32
1977 Carlin R, Chien S. Effect of hematocrit on the washout of xenon and iodoantipyrine from dog myocardium Circulation Research. 40: 505-509. PMID 856485  0.32
1977 Carlin R, Chien S. Partition of xenon and iodoantipyrine among erythrocytes, plasma, and myocardium Circulation Research. 40: 497-504. PMID 852104  0.32
1977 Chien S. Rheology of sickle cells and erythrocyte content Blood Cells. 3: 283-303.  0.32
1977 Chien S. Summing up I. Rheological methods Blood Cells. 3: 427-430.  0.32
1977 Chien S. Principles and techniques for assessing erythrocyte deformability Blood Cells. 3: 71-99.  0.32
1977 Chen RYZ, Chien S. Hemodynamic consequences of abnormal blood rheology in surface hypothermia Federation Proceedings. 36.  0.32
1976 Chien S. Significance of macrorheology and microrheology in atherogenesis Annals of the New York Academy of Sciences. 10-27. PMID 1070264  0.32
1976 Chien S. Electrochemical interactions between erythrocyte surfaces Thrombosis Research. 8: 189-202. PMID 936075 DOI: 10.1016/0049-3848(76)90062-1  0.32
1976 Jan KM, Chien S. Mechanism of heparin induced red cell aggregation Microvascular Research. 11: 121.  0.32
1974 Chien S, Usami S. Rate and mechanism of release of antidiuretic hormone after hemorrhage Circ.Shock. 1: 71-80.  0.32
1973 Usami S, Chien S. Optical reflectometry of red cell aggregation under shear flow Bibliotheca Anatomica. 11: 91-97. PMID 4789096  0.32
1973 Chien S. Force balance at the surfaces of aggregating cells Bibliotheca Anatomica. 11: 303-309. PMID 4789054  0.32
1973 Jan KM, Chien S. Role of the electrostatic repulsive force in red cell interactions Bibliotheca Anatomica. 11: 281-288. PMID 4789052  0.32
1973 Chien S. Electrochemical and ultrastructural aspects of red cell aggregation Bibliotheca Anatomica. 11: 244-250. PMID 4789047  0.32
1973 Usami S, Chien S. Shear deformation of red cell ghosts Biorheology. 10: 425-430. PMID 4772013  0.32
1973 Jan KM, Chien S. Role of surface electric charge in red blood cell interactions Journal of General Physiology. 61: 638-654. PMID 4705641  0.32
1973 Chien S, Jan Km. Ultrastructural basis of the mechanism of rouleaux formation Microvascular Research. 5: 155-166. PMID 4694282 DOI: 10.1016/0026-2862(73)90068-X  0.32
1973 Chien S, Jan K. Red cell aggregation by macromolecules: roles of surface adsorption and electrostatic repulsion Journal of Supramolecular and Cellular Biochemistry. 1: 385-409. PMID 4358445  0.32
1971 Chien S. Hemodynamics in Hemorrhage: Influences of Sympathetic Nerves and Pentobarbital Anesthesia Proceedings of the Society For Experimental Biology and Medicine. 136: 271-275. PMID 5540623 DOI: 10.3181/00379727-136-35244  0.32
1971 Miller LH, Chien S. Density distribution of red cells infected by Plasmodium knowlesi and Plasmodium coatneyi Experimental Parasitology. 29: 451-456. PMID 5003357 DOI: 10.1016/0014-4894(71)90054-3  0.32
1971 Chien S. A theory for the quantification of transcapillary exchange in the presence of shunt flow Circulation Research. 29: 173-180. PMID 4935839  0.32
1970 Chien S. Shear dependence of effective cell volume as a determinant of blood viscosity Science. 168: 977-979. PMID 5441028  0.32
1970 Chien S. Obituary. Magnus Ingstrup Gregersen 1903-1969 Biorheology. 6: 155-159. PMID 4907512  0.32
1969 Chien S, Usami S. Effects of hemorrhage on anesthetized dogs: role of the sympathetic system The American Journal of Physiology. 216: 1322-1329. PMID 5786718  0.32
1965 CHIEN S, USAMI S. CIRCULATION OF SYMPATHECTOMIZED DOGS UNDER PENTOBARBITAL ANESTHESIA The American Journal of Physiology. 208: 790-794. PMID 14274814  0.32
1964 CHIEN S. ROLE OF SYMPATHETIC NERVOUS SYSTEM IN SURVIVING ACUTE HEMORRHAGE The American Journal of Physiology. 206: 21-24. PMID 14111445  0.32
1960 CHIEN S. Supersensitivity of denervated superior cervical ganglion to acetylcholine The American Journal of Physiology. 198: 949-954. PMID 13809841  0.32
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