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Alexis N. LaCrue, Ph.D. - Publications

Affiliations: 
2007 University of Missouri - Columbia, Columbia, MO, United States 
Area:
Parasitology Biology, Microbiology Biology
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Neelarapu R, Maignan JR, Lichorowic CL, Monastyrskyi A, Mutka TS, LaCrue AN, Blake LD, Casandra D, Mashkouri S, Burrows JN, Willis PA, Kyle DE, Manetsch R. Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure-Activity and Structure-Property Relationship Studies. Journal of Medicinal Chemistry. PMID 29215279 DOI: 10.1021/Acs.Jmedchem.7B00738  0.409
2016 Maignan JR, Lichorowic CL, Giarrusso J, Blake L, Casandra D, Mutka TS, LaCrue AN, Burrows JN, Willis PA, Kyle DE, Manetsch R. ICI 56,780 Optimization: Structural-Activity and Relationship Studies of 7-(2-phenoxyethoxy)-4(1H)-quinolones with Antimalarial Activity. Journal of Medicinal Chemistry. PMID 27291102 DOI: 10.1021/Acs.Jmedchem.6B00759  0.379
2014 Cross RM, Flanigan DL, Monastyrskyi A, LaCrue AN, Sáenz FE, Maignan JR, Mutka TS, White KL, Shackleford DM, Bathurst I, Fronczek FR, Wojtas L, Guida WC, Charman SA, Burrows JN, et al. Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium. Journal of Medicinal Chemistry. 57: 8860-79. PMID 25148516 DOI: 10.1021/Jm500942V  0.416
2014 Chen N, LaCrue AN, Teuscher F, Waters NC, Gatton ML, Kyle DE, Cheng Q. Fatty acid synthesis and pyruvate metabolism pathways remain active in dihydroartemisinin-induced dormant ring stages of Plasmodium falciparum. Antimicrobial Agents and Chemotherapy. 58: 4773-81. PMID 24913167 DOI: 10.1128/Aac.02647-14  0.438
2013 Sáenz FE, Lacrue AN, Cross RM, Maignan JR, Udenze KO, Manetsch R, Kyle DE. 4-(1H)-Quinolones and 1,2,3,4-Tetrahydroacridin-9(10H)-ones prevent the transmission of Plasmodium falciparum to Anopheles freeborni. Antimicrobial Agents and Chemotherapy. 57: 6187-95. PMID 24080648 DOI: 10.1128/Aac.00492-13  0.553
2013 Nilsen A, LaCrue AN, White KL, Forquer IP, Cross RM, Marfurt J, Mather MW, Delves MJ, Shackleford DM, Saenz FE, Morrisey JM, Steuten J, Mutka T, Li Y, Wirjanata G, et al. Quinolone-3-diarylethers: a new class of antimalarial drug. Science Translational Medicine. 5: 177ra37. PMID 23515079 DOI: 10.1126/Scitranslmed.3005029  0.541
2013 Roberts RN, Schlarman MS, Kariuki MM, Lacrue AN, Ou R, Beerntsen BT. Expression profile of the Plasmodium falciparum intra-erythrocytic stage protein, PF3D7_1363700. Malaria Journal. 12: 66. PMID 23418676 DOI: 10.1186/1475-2875-12-66  0.656
2013 Lacrue AN, Sáenz FE, Cross RM, Udenze KO, Monastyrskyi A, Stein S, Mutka TS, Manetsch R, Kyle DE. 4(1H)-Quinolones with liver stage activity against Plasmodium berghei. Antimicrobial Agents and Chemotherapy. 57: 417-24. PMID 23129047 DOI: 10.1128/Aac.00793-12  0.456
2012 Schlarman MS, Roberts RN, Kariuki MM, LaCrue AN, Ou R, Beerntsen BT. PFE0565w, a Plasmodium falciparum protein expressed in salivary gland sporozoites. The American Journal of Tropical Medicine and Hygiene. 86: 943-54. PMID 22665598 DOI: 10.4269/Ajtmh.2012.11-0797  0.66
2012 Schlarman MS, Roberts RN, Kariuki MM, LaCrue AN, Ou R, Beerntsen BT. Transcript and protein expression profile of PF11_0394, a Plasmodium falciparum protein expressed in salivary gland sporozoites. Malaria Journal. 11: 80. PMID 22443220 DOI: 10.1186/1475-2875-11-80  0.661
2011 LaCrue AN, Scheel M, Kennedy K, Kumar N, Kyle DE. Effects of artesunate on parasite recrudescence and dormancy in the rodent malaria model Plasmodium vinckei. Plos One. 6: e26689. PMID 22039533 DOI: 10.1371/Journal.Pone.0026689  0.549
2006 LaCrue AN, Sivaguru M, Walter MF, Fidock DA, James AA, Beerntsen BT. A ubiquitous Plasmodium protein displays a unique surface labeling pattern in sporozoites. Molecular and Biochemical Parasitology. 148: 199-209. PMID 16697061 DOI: 10.1016/J.Molbiopara.2006.03.016  0.778
2005 Lacrue AN, James AA, Beerntsen BT. The novel Plasmodium gallinaceum sporozoite protein, Pg93, is preferentially expressed in the nucleus of oocyst sporozoites. The American Journal of Tropical Medicine and Hygiene. 73: 634-43. PMID 16172495 DOI: 10.4269/Ajtmh.2005.73.634  0.755
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