Luis M. Schang - Publications

Affiliations: 
Biochemistry University of Alberta, Edmonton, Alberta, Canada 
Area:
Biochemistry

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Correa Sierra CB, Schang LM. On the Sensitivity of the Virion Envelope to Lipid Peroxidation. Microbiology Spectrum. e0300922. PMID 36125312 DOI: 10.1128/spectrum.03009-22  0.347
2022 Rychlowska M, Agyapong A, Weinfeld M, Schang LM. Zika Virus Induces Mitotic Catastrophe in Human Neural Progenitors by Triggering Unscheduled Mitotic Entry in the Presence of DNA Damage While Functionally Depleting Nuclear PNKP. Journal of Virology. e0033322. PMID 35412344 DOI: 10.1128/jvi.00333-22  0.306
2021 Schang LM, Hu MY, Cortes EF, Sun K. Chromatin-mediated epigenetic regulation of HSV-1 transcription as a potential target in antiviral therapy. Antiviral Research. 105103. PMID 34082058 DOI: 10.1016/j.antiviral.2021.105103  0.328
2019 Hu M, Depledge DP, Flores Cortes E, Breuer J, Schang LM. Chromatin dynamics and the transcriptional competence of HSV-1 genomes during lytic infections. Plos Pathogens. 15: e1008076. PMID 31725813 DOI: 10.1371/Journal.Ppat.1008076  0.396
2019 Cullen B, Schang L. Decision letter: Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9 Elife. DOI: 10.7554/Elife.51662.Sa1  0.31
2018 Schang LM. Timing Is Everything. Mbio. 9. PMID 29295914 DOI: 10.1128/Mbio.02140-17  0.377
2018 Speerstra S, Chistov AA, Proskurin GV, Aralov AV, Ulashchik EA, Streshnev PP, Shmanai VV, Korshun VA, Schang LM. Antivirals acting on viral envelopes via biophysical mechanisms of action. Antiviral Research. 149: 164-173. PMID 29191427 DOI: 10.1016/J.Antiviral.2017.11.018  0.43
2017 Behrendt P, Perin P, Menzel N, Banda D, Pfaender S, Alves MP, Thiel V, Meulemann P, Colpitts CC, Schang LM, Vondran FWR, Anggakusuma, Manns MP, Steinmann E, Pietschmann T. Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry. Antiviral Research. PMID 28923507 DOI: 10.1016/J.Antiviral.2017.09.006  0.382
2017 Andrei G, Carter K, Janeba Z, Sampath A, Schang LM, Tarbet EB, Vere Hodge RA, Bray M, Esté JA. Highlights of the 30th International Conference on Antiviral Research. Antiviral Research. PMID 28774800 DOI: 10.1016/J.Antiviral.2017.07.017  0.39
2016 Gibeault RL, Conn KL, Bildersheim MD, Schang LM. An Essential Viral Transcription Activator Modulates Chromatin Dynamics. Plos Pathogens. 12: e1005842. PMID 27575707 DOI: 10.1371/Journal.Ppat.1005842  0.426
2015 Perin PM, Haid S, Brown RJ, Doerrbecker J, Schulze K, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Baktash YM, Vondran FW, Speerstra S, Awadh A, Mukhtarov F, ... Schang LM, et al. Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1. Hepatology (Baltimore, Md.). PMID 26248546 DOI: 10.1002/Hep.28111  0.367
2015 Kusuma A, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, et al. Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication via blockage of membranous web formation. Hepatology (Baltimore, Md.). PMID 25999047 DOI: 10.1002/Hep.27913  0.393
2015 Perin P, Haid S, Brown R, Schulze K, Colpitts C, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Andonyadis Y, Vondran F, Kirschning A, Schang L, Müller R, et al. P0674 : Clinically approved T-type calcium channel inhibitors prevent hepatitis C virus (HCV) membrane fusion in a genotype-dependent manner Journal of Hepatology. 62: S574-S575. DOI: 10.1016/S0168-8278(15)30878-3  0.342
2014 Tsai K, Chan L, Gibeault R, Conn K, Dheekollu J, Domsic J, Marmorstein R, Schang LM, Lieberman PM. Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection. Journal of Virology. 88: 14350-63. PMID 25275136 DOI: 10.1128/Jvi.01895-14  0.416
2014 Colpitts CC, Schang LM. A small molecule inhibits virion attachment to heparan sulfate- or sialic acid-containing glycans. Journal of Virology. 88: 7806-17. PMID 24789779 DOI: 10.1128/Jvi.00896-14  0.425
2014 Anggakusuma, Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, Behrendt P, Brown RJ, Bankwitz D, Steinmann J, Ott M, Meuleman P, Rice CM, Ploss A, Pietschmann T, et al. Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut. 63: 1137-49. PMID 23903236 DOI: 10.1136/Gutjnl-2012-304299  0.379
2014 Schang LM. Biophysical approaches to entry inhibitor antivirals with a broad spectrum of action Future Virology. 9: 283-299. DOI: 10.2217/Fvl.13.130  0.442
2013 Conn KL, Hendzel MJ, Schang LM. The differential mobilization of histones H3.1 and H3.3 by herpes simplex virus 1 relates histone dynamics to the assembly of viral chromatin. Plos Pathogens. 9: e1003695. PMID 24130491 DOI: 10.1371/Journal.Ppat.1003695  0.339
2013 Conn KL, Schang LM. Chromatin dynamics during lytic infection with herpes simplex virus 1. Viruses. 5: 1758-86. PMID 23863878 DOI: 10.3390/V5071758  0.407
2013 Colpitts CC, Ustinov AV, Epand RF, Epand RM, Korshun VA, Schang LM. 5-(Perylen-3-yl)ethynyl-arabino-uridine (aUY11), an arabino-based rigid amphipathic fusion inhibitor, targets virion envelope lipids to inhibit fusion of influenza virus, hepatitis C virus, and other enveloped viruses. Journal of Virology. 87: 3640-54. PMID 23283943 DOI: 10.1128/Jvi.02882-12  0.456
2013 Kusuma A, Colpitts C, Schang L, Rachmawati H, Frentzen A, Pfaender S, Behrendt P, Brown R, Bankwitz D, Steinmann J, Ott M, Meuleman P, Pietschmann T, Steinmann E. 1162 Turmeric Curcumin Inhibits Entry Of All Hepatitis C Virus Genotypes Into Human Liver Cells Journal of Hepatology. 58. DOI: 10.1016/S0168-8278(13)61163-0  0.356
2012 Lacasse JJ, Schang LM. Herpes simplex virus 1 DNA is in unstable nucleosomes throughout the lytic infection cycle, and the instability of the nucleosomes is independent of DNA replication. Journal of Virology. 86: 11287-300. PMID 22875975 DOI: 10.1128/Jvi.01468-12  0.348
2011 Conn KL, Hendzel MJ, Schang LM. Core histones H2B and H4 are mobilized during infection with herpes simplex virus 1. Journal of Virology. 85: 13234-52. PMID 21994445 DOI: 10.1128/Jvi.06038-11  0.356
2011 Ciesek S, von Hahn T, Colpitts CC, Schang LM, Friesland M, Steinmann J, Manns MP, Ott M, Wedemeyer H, Meuleman P, Pietschmann T, Steinmann E. The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry. Hepatology (Baltimore, Md.). 54: 1947-55. PMID 21837753 DOI: 10.1002/Hep.24610  0.38
2011 Colpitts CC, Ustinov AV, Korshun VA, Schang LM. Rigid Amphipathic Fusion Inhibitors (RAFIs) Inhibit Infectivity of Enveloped Viruses by Targeting Envelope Lipids to Prevent Fusion With Cellular Membranes Antiviral Research. 90. DOI: 10.1016/J.Antiviral.2011.03.029  0.395
2010 St Vincent MR, Colpitts CC, Ustinov AV, Muqadas M, Joyce MA, Barsby NL, Epand RF, Epand RM, Khramyshev SA, Valueva OA, Korshun VA, Tyrrell DL, Schang LM. Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped viruses. Proceedings of the National Academy of Sciences of the United States of America. 107: 17339-44. PMID 20823220 DOI: 10.1073/Pnas.1010026107  0.435
2010 Rieger AM, Hall BE, Luong le T, Schang LM, Barreda DR. Conventional apoptosis assays using propidium iodide generate a significant number of false positives that prevent accurate assessment of cell death. Journal of Immunological Methods. 358: 81-92. PMID 20381494 DOI: 10.1016/J.Jim.2010.03.019  0.344
2010 Lacasse JJ, Schang LM. During lytic infections, herpes simplex virus type 1 DNA is in complexes with the properties of unstable nucleosomes. Journal of Virology. 84: 1920-33. PMID 20007274 DOI: 10.1128/Jvi.01934-09  0.336
2009 Vincent MS, Ustinov A, Barsby N, Joyce M, Tyrrell L, Epand R, Korshun V, Schang L. dUY11, A Rigid Amphipathic Fusion Inhibitor, Inhibits HCV Infectivity by Modulating Membrane Curvature Antiviral Research. 82. DOI: 10.1016/J.Antiviral.2009.02.025  0.354
2008 Conn KL, Hendzel MJ, Schang LM. Linker histones are mobilized during infection with herpes simplex virus type 1. Journal of Virology. 82: 8629-46. PMID 18579611 DOI: 10.1128/Jvi.00616-08  0.403
2008 Vincent MS, Korshun V, Ustinov A, Schang L. Herpes Simplex Virus Type 2 Exposed to Rigid Amphipathic Fusion Inhibitors (RAFIs) are not Infectious in a Mouse Vaginal Model Antiviral Research. 78. DOI: 10.1016/J.Antiviral.2008.01.141  0.408
2007 Vincent MS, Korkach S, Valueva O, Korshun V, Ustinov A, Schang L. Nucleosidic Fusion Inhibitors Antiviral Research. 74. DOI: 10.1016/J.Antiviral.2007.01.156  0.315
2006 Schang LM, St Vincent MR, Lacasse JJ. Five years of progress on cyclin-dependent kinases and other cellular proteins as potential targets for antiviral drugs. Antiviral Chemistry & Chemotherapy. 17: 293-320. PMID 17249245 DOI: 10.1177/095632020601700601  0.432
2006 Schang LM. First demonstration of the effectiveness of inhibitors of cellular protein kinases in antiviral therapy. Expert Review of Anti-Infective Therapy. 4: 953-6. PMID 17181411 DOI: 10.1586/14787210.4.6.953  0.425
2006 Schang LM. Herpes simplex viruses in antiviral drug discovery. Current Pharmaceutical Design. 12: 1357-70. PMID 16611120 DOI: 10.2174/138161206776361174  0.445
2006 Morris KE, Schang LM, Brindley DN. Lipid phosphate phosphatase-2 activity regulates S-phase entry of the cell cycle in Rat2 fibroblasts. The Journal of Biological Chemistry. 281: 9297-306. PMID 16467304 DOI: 10.1074/Jbc.M511710200  0.317
2006 Schang LM. Pharmacological cyclin-dependent kinase inhibitors (PCIs) as potential antiviral drugs Anti-Infective Agents in Medicinal Chemistry. 5: 345-355. DOI: 10.2174/187152106778520424  0.475
2005 Schang LM, Coccaro E, Lacasse JJ. CDK inhibitory nucleoside analogs prevent transcription from viral genomes Nucleosides, Nucleotides and Nucleic Acids. 24: 829-837. PMID 16248044 DOI: 10.1081/Ncn-200060314  0.477
2005 Schang LM. Discovery of the antiviral activities of pharmacologic cyclin-dependent kinase inhibitors: from basic to applied science. Expert Review of Anti-Infective Therapy. 3: 145-9. PMID 15918771 DOI: 10.1586/14787210.3.2.145  0.397
2005 Schang LM. Advances on cyclin-dependent kinases (CDKs) as novel targets for antiviral drugs Current Drug Targets - Infectious Disorders. 5: 29-37. PMID 15777196 DOI: 10.2174/1568005053174609  0.456
2005 Lacasse JJ, Provencher VMI, Urbanowski MD, Schang LM. Purine and nonpurine pharmacological cyclin-dependent kinase inhibitors target initiation of viral transcription Therapy. 2: 77-90. DOI: 10.2217/14750708.2.1.77  0.51
2004 Provencher VMI, Coccaro E, Lacasse JJ, Schang LM. Antiviral drugs that target cellular proteins may play major roles in combating HIV resistance Current Pharmaceutical Design. 10: 4081-4101. PMID 15579090 DOI: 10.2174/1381612043382422  0.33
2004 Diwan P, Lacasse JJ, Schang LM. Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factors. Journal of Virology. 78: 9352-65. PMID 15308730 DOI: 10.1128/Jvi.78.17.9352-9365.2004  0.461
2004 Banchio C, Schang LM, Vance DE. Phosphorylation of Sp1 by cyclin-dependent kinase 2 modulates the role of Sp1 in CTP:phosphocholine cytidylyltransferase alpha regulation during the S phase of the cell cycle. The Journal of Biological Chemistry. 279: 40220-6. PMID 15247247 DOI: 10.1074/Jbc.M406468200  0.316
2004 Schang LM. Effects of pharmacological cyclin-dependent kinase inhibitors on viral transcription and replication. Biochimica Et Biophysica Acta. 1697: 197-209. PMID 15023361 DOI: 10.1016/J.Bbapap.2003.11.024  0.48
2003 Schang LM. The cell cycle, cyclin-dependent kinases, and viral infections: new horizons and unexpected connections. Progress in Cell Cycle Research. 5: 103-24. PMID 14593705  0.348
2002 Schang LM. Cyclin-dependent kinases as cellular targets for antiviral drugs. The Journal of Antimicrobial Chemotherapy. 50: 779-92. PMID 12460995 DOI: 10.1093/Jac/Dkf227  0.465
2002 Schang LM, Bantly A, Knockaert M, Shaheen F, Meijer L, Malim MH, Gray NS, Schaffer PA. Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins. Journal of Virology. 76: 7874-82. PMID 12097601 DOI: 10.1128/Jvi.76.15.7874-7882.2002  0.49
2002 Schang LM, Bantly A, Schaffer PA. Explant-induced reactivation of herpes simplex virus occurs in neurons expressing nuclear cdk2 and cdk4. Journal of Virology. 76: 7724-35. PMID 12097586 DOI: 10.1128/Jvi.76.15.7724-7735.2002  0.332
2001 Schang LM. Cellular proteins (cyclin dependent kinases) as potential targets for antiviral drugs Antiviral Chemistry and Chemotherapy, Supplement. 12: 157-178. PMID 11594683  0.405
2000 Schang LM, Hwang GJ, Dynlacht BD, Speicher DW, Bantly A, Schaffer PA, Shilatifard A, Ge H, Shiekhattar R. Human PC4 is a substrate-specific inhibitor of RNA polymerase II phosphorylation. The Journal of Biological Chemistry. 275: 6071-4. PMID 10692395 DOI: 10.1074/Jbc.275.9.6071  0.321
2000 Schang LM, Rosenberg A, Schaffer PA. Roscovitine, a specific inhibitor of cellular cyclin-dependent kinases, inhibits herpes simplex virus DNA synthesis in the presence of viral early proteins Journal of Virology. 74: 2107-2120. PMID 10666240 DOI: 10.1128/Jvi.74.5.2107-2120.2000  0.458
1999 Jordan R, Schang L, Schaffer PA. Transactivation of herpes simplex virus type 1 immediate-early gene expression by virion-associated factors is blocked by an inhibitor of cyclin-dependent protein kinases. Journal of Virology. 73: 8843-7. PMID 10482641 DOI: 10.1128/Jvi.73.10.8843-8847.1999  0.471
1999 Schang LM, Rosenberg A, Schaffer PA. Transcription of herpes simplex virus immediate-early and early genes is inhibited by roscovitine, an inhibitor specific for cellular cyclin-dependent kinases Journal of Virology. 73: 2161-2172. PMID 9971799 DOI: 10.1128/Jvi.73.3.2161-2172.1999  0.471
1998 Schang LM, Phillips J, Schaffer PA. Requirement for cellular cyclin-dependent kinases in herpes simplex virus replication and transcription Journal of Virology. 72: 5626-5637. PMID 9621021 DOI: 10.1128/Jvi.72.7.5626-5637.1998  0.468
1997 Schang LM, Jones C. Analysis of bovine herpesvirus 1 transcripts during a primary infection of trigeminal ganglia of cattle Journal of Virology. 71: 6786-6795. PMID 9261403 DOI: 10.1128/Jvi.71.9.6786-6795.1997  0.375
1996 Schang LM, Hossain A, Jones C. The latency-related gene of bovine herpesvirus 1 encodes a product which inhibits cell cycle progression Journal of Virology. 70: 3807-3814. PMID 8648716 DOI: 10.1128/Jvi.70.6.3807-3814.1996  0.401
1995 Hossain A, Schang LM, Jones C. Identification of gene products encoded by the latency-related gene of bovine herpesvirus 1 Journal of Virology. 69: 5345-5352. PMID 7636978 DOI: 10.1128/Jvi.69.9.5345-5352.1995  0.348
1994 Schang LM, Kutish GF, Osorio FA. Correlation between precolonization of trigeminal ganglia by attenuated strains of pseudorabies virus and resistance to wild-type virus latency Journal of Virology. 68: 8470-8476. PMID 7966645 DOI: 10.1128/Jvi.68.12.8470-8476.1994  0.312
1994 Schang LM, Osorio FA. Quantitation of latency established by attenuated strains of Pseudorabies (Aujeszky's disease) virus Journal of Virological Methods. 50: 269-280. PMID 7714050 DOI: 10.1016/0166-0934(94)90183-X  0.335
Show low-probability matches.