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Yizhou Dong, Ph.D. - Publications

Affiliations: 
2009 Pharmaceutical Sciences University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmaceutical Chemistry, Pharmacology
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhang X, Zhao W, Nguyen GN, Zhang C, Zeng C, Yan J, Du S, Hou X, Li W, Jiang J, Deng B, McComb DW, Dorkin R, Shah A, Barrera L, ... ... Dong Y, et al. Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing. Science Advances. 6. PMID 32937374 DOI: 10.1126/Sciadv.Abc2315  0.339
2020 Zeng C, Hou X, Yan J, Zhang C, Li W, Zhao W, Du S, Dong Y. Leveraging mRNA Sequences and Nanoparticles to Deliver SARS-CoV-2 Antigens In Vivo. Advanced Materials (Deerfield Beach, Fla.). e2004452. PMID 32875709 DOI: 10.1002/Adma.202004452  0.307
2020 Zhao P, Hou X, Yan J, Du S, Xue Y, Li W, Xiang G, Dong Y. Long-term storage of lipid-like nanoparticles for mRNA delivery. Bioactive Materials. 5: 358-363. PMID 32206737 DOI: 10.1016/J.Bioactmat.2020.03.001  0.303
2020 Li W, Chan C, Zeng C, Turk R, Behlke MA, Cheng X, Dong Y. Rational Design of Small Molecules to Enhance Genome Editing Efficiency by Selectively Targeting Distinct Functional States of CRISPR-Cas12a. Bioconjugate Chemistry. PMID 32119776 DOI: 10.1021/Acs.Bioconjchem.0C00062  0.309
2020 Guo S, Vieweger M, Zhang K, Yin H, Wang H, Li X, Li S, Hu S, Sparreboom A, Evers BM, Dong Y, Chiu W, Guo P. Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy. Nature Communications. 11: 972. PMID 32080195 DOI: 10.1038/S41467-020-14780-5  0.34
2019 Zhang C, Zhang X, Zhao W, Zeng C, Li W, Li B, Luo X, Li J, Jiang J, Deng B, McComb DW, Dong Y. Chemotherapy drugs derived nanoparticles encapsulating mRNA encoding tumor suppressor proteins to treat triple-negative breast cancer. Nano Research. 12: 855-861. PMID 31737223 DOI: 10.1007/S12274-019-2308-9  0.344
2019 Dong Y, Siegwart DJ, Anderson DG. Strategies, design, and chemistry in siRNA delivery systems. Advanced Drug Delivery Reviews. PMID 31102606 DOI: 10.1016/J.Addr.2019.05.004  0.364
2018 Luo X, Zhao W, Li B, Zhang X, Zhang C, Bratasz A, Deng B, McComb DW, Dong Y. Co-delivery of mRNA and SPIONs through amino-ester nanomaterials. Nano Research. 11: 5596-5603. PMID 31737222 DOI: 10.1007/S12274-018-2082-0  0.346
2018 Zhao W, Zhang C, Li B, Zhang X, Luo X, Zeng C, Li W, Gao M, Dong Y. Lipid Polymer Hybrid Nanomaterials for mRNA Delivery. Cellular and Molecular Bioengineering. 11: 397-406. PMID 30555598 DOI: 10.1007/S12195-018-0536-9  0.313
2018 Li B, Zhang X, Dong Y. Nanoscale platforms for messenger RNA delivery. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. e1530. PMID 29726120 DOI: 10.1002/Wnan.1530  0.377
2017 Li B, Dong Y. Preparation and Optimization of Lipid-Like Nanoparticles for mRNA Delivery. Methods in Molecular Biology (Clifton, N.J.). 1632: 207-217. PMID 28730441 DOI: 10.1007/978-1-4939-7138-1_13  0.334
2017 Zhang X, Li B, Luo X, Zhao W, Jiang J, Zhang C, Gao M, Chen X, Dong Y. Biodegradable Amino-ester Nanomaterials for Cas9 mRNA Delivery in Vitro and in Vivo. Acs Applied Materials & Interfaces. PMID 28685575 DOI: 10.1021/Acsami.7B08163  0.358
2017 Luo X, Li B, Zhang X, Zhao W, Bratasz A, Deng B, McComb DW, Dong Y. Dual-functional lipid-like nanoparticles for delivery of mRNA and MRI contrast agents. Nanoscale. PMID 28067926 DOI: 10.1039/C6Nr08496F  0.336
2016 Luo X, Wang W, Dorkin JR, Veiseh O, Chang PH, Abutbul-Ionita I, Danino D, Langer R, Anderson DG, Dong Y. Poly(glycoamidoamine) brush nanomaterials for systemic siRNA delivery in vivo. Biomaterials Science. PMID 27921096 DOI: 10.1039/C6Bm00683C  0.321
2016 Li B, Luo X, Deng B, Giancola JB, McComb DW, Schmittgen TD, Dong Y. Effects of local structural transformation of lipid-like compounds on delivery of messenger RNA. Scientific Reports. 6: 22137. PMID 26916931 DOI: 10.1038/Srep22137  0.36
2016 Yin H, Song CQ, Dorkin JR, Zhu LJ, Li Y, Wu Q, Park A, Yang J, Suresh S, Bizhanova A, Gupta A, Bolukbasi MF, Walsh S, Bogorad RL, Gao G, ... ... Dong Y, et al. Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo. Nature Biotechnology. PMID 26829318 DOI: 10.1038/Nbt.3471  0.309
2016 Dong Y, Dorkin JR, Wang W, Chang PH, Webber MJ, Tang BC, Yang J, Abutbul-Ionita I, Danino D, DeRosa F, Heartlein M, Langer R, Anderson DG. Poly(glycoamidoamine) brushes formulated nanomaterials for systemic siRNA and mRNA delivery in vivo. Nano Letters. PMID 26727632 DOI: 10.1021/Acs.Nanolett.5B02428  0.323
2015 Li B, Luo X, Deng B, Wang J, McComb DW, Shi Y, Gaensler KM, Tan X, Dunn A, Kerlin B, Dong Y. An Orthogonal Array Optimization of Lipid-like Nanoparticles for mRNA Delivery in vivo. Nano Letters. PMID 26529392 DOI: 10.1021/Acs.Nanolett.5B03528  0.35
2015 Khan OF, Zaia EW, Jhunjhunwala S, Xue W, Cai W, Yun DS, Barnes CM, Dahlman JE, Dong Y, Pelet JM, Webber MJ, Tsosie JK, Jacks TE, Langer R, Anderson DG. Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature. Nano Letters. 15: 3008-16. PMID 25789998 DOI: 10.1021/Nl5048972  0.306
2014 Eltoukhy AA, Chen D, Veiseh O, Pelet JM, Yin H, Dong Y, Anderson DG. Nucleic acid-mediated intracellular protein delivery by lipid-like nanoparticles. Biomaterials. 35: 6454-61. PMID 24831975 DOI: 10.1016/J.Biomaterials.2014.04.014  0.312
2014 Dahlman JE, Barnes C, Khan OF, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, et al. In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight. Nature Nanotechnology. 9: 648-55. PMID 24813696 DOI: 10.1038/Nnano.2014.84  0.308
2014 Dong Y, Love KT, Dorkin JR, Sirirungruang S, Zhang Y, Chen D, Bogorad RL, Yin H, Chen Y, Vegas AJ, Alabi CA, Sahay G, Olejnik KT, Wang W, Schroeder A, et al. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. Proceedings of the National Academy of Sciences of the United States of America. 111: 3955-60. PMID 24516150 DOI: 10.1073/Pnas.1322937111  0.312
2013 Zhang Y, Pelet JM, Heller DA, Dong Y, Chen D, Gu Z, Joseph BJ, Wallas J, Anderson DG. Lipid-modified aminoglycoside derivatives for in vivo siRNA delivery. Advanced Materials (Deerfield Beach, Fla.). 25: 4641-5. PMID 23813808 DOI: 10.1002/Adma.201301917  0.326
2013 Zhang Y, Pelet JM, Heller DA, Dong Y, Chen D, Gu Z, Joseph BJ, Wallas J, Anderson DG. Drug Delivery: Lipid-Modified Aminoglycoside Derivatives for In Vivo siRNA Delivery (Adv. Mater. 33/2013) Advanced Materials. 25: 4680-4680. DOI: 10.1002/Adma.201370207  0.304
2012 Lee KH, Morris-Natschke S, Qian K, Dong Y, Yang X, Zhou T, Belding E, Wu SF, Wada K, Akiyama T. Recent Progress of Research on Herbal Products Used in Traditional Chinese Medicine: the Herbs belonging to The Divine Husbandman's Herbal Foundation Canon ( Shén Nóng Běn Cǎo Jīng). Journal of Traditional and Complementary Medicine. 2: 6-26. PMID 24716110 DOI: 10.1016/S2225-4110(16)30066-9  0.555
2012 Wang LT, Pan SL, Chen TH, Dong Y, Lee KH, Teng CM. DYZ-2-90, a novel neo-tanshinlactone ring-opened compound, induces ERK-mediated mitotic arrest and subsequent apoptosis by activating JNK in human colorectal cancer cells. Chembiochem : a European Journal of Chemical Biology. 13: 1663-72. PMID 22761044 DOI: 10.1002/Cbic.201200191  0.515
2012 Chen D, Love KT, Chen Y, Eltoukhy AA, Kastrup C, Sahay G, Jeon A, Dong Y, Whitehead KA, Anderson DG. Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation. Journal of the American Chemical Society. 134: 6948-51. PMID 22475086 DOI: 10.1021/Ja301621Z  0.334
2012 Dong Y, Nakagawa-Goto K, Lai CY, Morris-Natschke SL, Bastow KF, Kim Y, Lee EY, Lee KH. Antitumor agents. 289. Design, synthesis, and anti-breast cancer activity in vivo of 4-amino-2H-benzo[h]chromen-2-one and 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one analogues with improved water solubility. Journal of Natural Products. 75: 370-7. PMID 22304236 DOI: 10.1021/Np2007878  0.512
2011 Dong Y, Nakagawa-Goto K, Lai CY, Morris-Natschke SL, Bastow KF, Lee KH. Antitumor agents 287. Substituted 4-amino-2H-pyran-2-one (APO) analogs reveal a new scaffold from neo-tanshinlactone with in vitro anticancer activity. Bioorganic & Medicinal Chemistry Letters. 21: 2341-4. PMID 21420855 DOI: 10.1016/J.Bmcl.2011.02.084  0.491
2011 Dong Y, Morris-Natschke SL, Lee KH. Biosynthesis, total syntheses, and antitumor activity of tanshinones and their analogs as potential therapeutic agents. Natural Product Reports. 28: 529-42. PMID 21225077 DOI: 10.1039/C0Np00035C  0.507
2011 Dong Y, Nakagawa-Goto K, Lai CY, Kim Y, Morris-Natschke SL, Lee EY, Bastow KF, Lee KH. Antitumor agents 279. Structure-activity relationship and in vivo studies of novel 2-(furan-2-yl)naphthalen-1-ol (FNO) analogs as potent and selective anti-breast cancer agents. Bioorganic & Medicinal Chemistry Letters. 21: 52-7. PMID 21147529 DOI: 10.1016/J.Bmcl.2010.11.077  0.505
2011 Dong Y, Nakagawa-Goto K, Lai CY, Morris-Natschke SL, Bastow KF, Lee KH. Antitumor agents 281. Design, synthesis, and biological activity of substituted 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one analogs (ATBO) as potent in vitro anticancer agents. Bioorganic & Medicinal Chemistry Letters. 21: 546-9. PMID 21087859 DOI: 10.1016/J.Bmcl.2010.10.074  0.52
2010 Chou LC, Tsai MT, Hsu MH, Wang SH, Way TD, Huang CH, Lin HY, Qian K, Dong Y, Lee KH, Huang LJ, Kuo SC. Design, synthesis, and preclinical evaluation of new 5,6- (or 6,7-) disubstituted-2-(fluorophenyl)quinolin-4-one derivatives as potent antitumor agents. Journal of Medicinal Chemistry. 53: 8047-58. PMID 20973552 DOI: 10.1021/Jm100780C  0.597
2010 Dong Y, Nakagawa-Goto K, Lai CY, Morris-Natschke SL, Bastow KF, Lee KH. Antitumor agents 278. 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs as potent in vitro anti-cancer agents. Bioorganic & Medicinal Chemistry Letters. 20: 4085-7. PMID 20542429 DOI: 10.1016/J.Bmcl.2010.05.079  0.518
2010 Dong Y, Shi Q, Pai HC, Peng CY, Pan SL, Teng CM, Nakagawa-Goto K, Yu D, Liu YN, Wu PC, Bastow KF, Morris-Natschke SL, Brossi A, Lang JY, Hsu JL, et al. Antitumor agents. 272. Structure-activity relationships and in vivo selective anti-breast cancer activity of novel neo-tanshinlactone analogues. Journal of Medicinal Chemistry. 53: 2299-308. PMID 20148565 DOI: 10.1021/Jm1000858  0.634
2010 Dong Y, Shi Q, Nakagawa-Goto K, Wu PC, Morris-Natschke SL, Brossi A, Bastow KF, Lang JY, Hung MC, Lee KH. Antitumor agents 270. Novel substituted 6-phenyl-4H-furo[3,2-c]pyran-4-one derivatives as potent and highly selective anti-breast cancer agents. Bioorganic & Medicinal Chemistry. 18: 803-8. PMID 20034799 DOI: 10.1016/J.Bmc.2009.11.049  0.51
2009 Dong Y, Shi Q, Nakagawa-Goto K, Wu PC, Bastow KF, Morris-Natschke SL, Lee KH. Antitumor agents 269. Non-aromatic ring-A neotanshinlactone analog, TNO, as a new class of potent antitumor agents. Bioorganic & Medicinal Chemistry Letters. 19: 6289-92. PMID 19819136 DOI: 10.1016/J.Bmcl.2009.09.092  0.53
2009 Dong Y, Shi Q, Liu YN, Wang X, Bastow KF, Lee KH. Antitumor agents. 266. Design, synthesis, and biological evaluation of novel 2-(furan-2-yl)naphthalen-1-ol derivatives as potent and selective antibreast cancer agents. Journal of Medicinal Chemistry. 52: 3586-90. PMID 19425534 DOI: 10.1021/Jm9001567  0.528
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