Year |
Citation |
Score |
2022 |
Schwerk J, Kemper L, Bussey KA, Lienenklaus S, Weiss S, Čičin-Šain L, Kröger A, Kalinke U, Collins CM, Speck SH, Messerle M, Wirth D, Brinkmann MM, Hauser H, Köster M. Type I Interferon Signaling Controls Gammaherpesvirus Latency In Vivo. Pathogens (Basel, Switzerland). 11. PMID 36558888 DOI: 10.3390/pathogens11121554 |
0.379 |
|
2020 |
Liu S, Lei Z, Li J, Wang L, Jia R, Liu Z, Jiang C, Gao Y, Liu M, Kuang L, Qian Z, Zhou D, Speck SH, Liang X. Interleukin 16 contributes to gammaherpesvirus pathogenesis by inhibiting viral reactivation. Plos Pathogens. 16: e1008701. PMID 32735617 DOI: 10.1371/Journal.Ppat.1008701 |
0.467 |
|
2020 |
Collins CM, Scharer CD, Murphy TJ, Boss JM, Speck SH. Murine gammaherpesvirus infection is skewed toward Igλ+ B cells expressing a specific heavy chain V-segment. Plos Pathogens. 16: e1008438. PMID 32353066 DOI: 10.1371/Journal.Ppat.1008438 |
0.53 |
|
2018 |
Feng Y, Livingston-Rosanoff D, Roback L, Sundararajan A, Speck SH, Mocarski ES, Daley-Bauer LP. Remarkably Robust Antiviral Immune Response despite Combined Deficiency in Caspase-8 and RIPK3. Journal of Immunology (Baltimore, Md. : 1950). PMID 30194111 DOI: 10.4049/Jimmunol.1800110 |
0.473 |
|
2017 |
Terrell S, Speck SH. Murine gammaherpesvirus M2 antigen modulates splenic B cell activation and terminal differentiation in vivo. Plos Pathogens. 13: e1006543. PMID 28767707 DOI: 10.1371/Journal.Ppat.1006543 |
0.547 |
|
2017 |
Hong S, Wang D, Horton JR, Zhang X, Speck SH, Blumenthal RM, Cheng X. Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. Nucleic Acids Research. PMID 28158710 DOI: 10.1093/Nar/Gkx057 |
0.33 |
|
2016 |
Wakeman BS, Izumiya Y, Speck SH. Identification of novel KSHV Orf50 transcripts: discovery of new RTA isoforms with variable transactivation potential. Journal of Virology. PMID 27795414 DOI: 10.1128/Jvi.01434-16 |
0.501 |
|
2015 |
O'Flaherty BM, Matar CG, Wakeman BS, Garcia A, Wilke CA, Courtney CL, Moore BB, Speck SH. CD8+ T Cell Response to Gammaherpesvirus Infection Mediates Inflammation and Fibrosis in Interferon Gamma Receptor-Deficient Mice. Plos One. 10: e0135719. PMID 26317335 DOI: 10.1371/Journal.Pone.0135719 |
0.446 |
|
2015 |
Matar CG, Jacobs NT, Speck SH, Lamb TJ, Moormann AM. Does EBV alter the pathogenesis of malaria? Parasite Immunology. 37: 433-445. PMID 26121587 DOI: 10.1111/Pim.12212 |
0.418 |
|
2015 |
Matar CG, Anthony NR, O'Flaherty BM, Jacobs NT, Priyamvada L, Engwerda CR, Speck SH, Lamb TJ. Gammaherpesvirus Co-infection with Malaria Suppresses Anti-parasitic Humoral Immunity. Plos Pathogens. 11: e1004858. PMID 25996913 DOI: 10.1371/Journal.Ppat.1004858 |
0.446 |
|
2015 |
Pinelli DF, Wakeman BS, Wagener ME, Speck SH, Ford ML. Rapamycin ameliorates the CTLA4-Ig-mediated defect in CD8(+) T cell immunity during gammaherpesvirus infection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15: 2576-87. PMID 25989700 DOI: 10.1111/Ajt.13326 |
0.382 |
|
2015 |
Collins CM, Speck SH. Interleukin 21 signaling in B cells is required for efficient establishment of murine gammaherpesvirus latency. Plos Pathogens. 11: e1004831. PMID 25875847 DOI: 10.1371/Journal.Ppat.1004831 |
0.474 |
|
2014 |
Rangaswamy US, O'Flaherty BM, Speck SH. Tyrosine 129 of the murine gammaherpesvirus M2 protein is critical for M2 function in vivo. Plos One. 9: e105197. PMID 25122496 DOI: 10.1371/Journal.Pone.0105197 |
0.52 |
|
2014 |
O'Flaherty BM, Soni T, Wakeman BS, Speck SH. The murine gammaherpesvirus immediate-early Rta synergizes with IRF4, targeting expression of the viral M1 superantigen to plasma cells. Plos Pathogens. 10: e1004302. PMID 25101696 DOI: 10.1371/Journal.Ppat.1004302 |
0.531 |
|
2014 |
Matar CG, Rangaswamy US, Wakeman BS, Iwakoshi N, Speck SH. Murine gammaherpesvirus 68 reactivation from B cells requires IRF4 but not XBP-1. Journal of Virology. 88: 11600-10. PMID 25078688 DOI: 10.1128/Jvi.01876-14 |
0.512 |
|
2014 |
Reese TA, Wakeman BS, Choi HS, Hufford MM, Huang SC, Zhang X, Buck MD, Jezewski A, Kambal A, Liu CY, Goel G, Murray PJ, Xavier RJ, Kaplan MH, Renne R, ... Speck SH, et al. Coinfection. Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter. Science (New York, N.Y.). 345: 573-7. PMID 24968940 DOI: 10.1126/Science.1254517 |
0.445 |
|
2014 |
Kaiser WJ, Daley-Bauer LP, Thapa RJ, Mandal P, Berger SB, Huang C, Sundararajan A, Guo H, Roback L, Speck SH, Bertin J, Gough PJ, Balachandran S, Mocarski ES. RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition. Proceedings of the National Academy of Sciences of the United States of America. 111: 7753-8. PMID 24821786 DOI: 10.1073/Pnas.1401857111 |
0.339 |
|
2014 |
Collins CM, Speck SH. Expansion of murine gammaherpesvirus latently infected B cells requires T follicular help. Plos Pathogens. 10: e1004106. PMID 24789087 DOI: 10.1371/Journal.Ppat.1004106 |
0.558 |
|
2014 |
Scott FM, Speck SH. A tissue culture model of murine gammaherpesvirus replication reveals roles for the viral cyclin in both virus replication and egress from infected cells. Plos One. 9: e93871. PMID 24695529 DOI: 10.1371/Journal.Pone.0093871 |
0.498 |
|
2014 |
Wakeman BS, Johnson LS, Paden CR, Gray KS, Virgin HW, Speck SH. Identification of alternative transcripts encoding the essential murine gammaherpesvirus lytic transactivator RTA. Journal of Virology. 88: 5474-90. PMID 24574412 DOI: 10.1128/Jvi.03110-13 |
0.583 |
|
2014 |
Rangaswamy US, Speck SH. Murine gammaherpesvirus M2 protein induction of IRF4 via the NFAT pathway leads to IL-10 expression in B cells. Plos Pathogens. 10: e1003858. PMID 24391506 DOI: 10.1371/Journal.Ppat.1003858 |
0.469 |
|
2013 |
Beus JM, Hashmi SS, Selvaraj SA, Duan D, Stempora LL, Monday SA, Cheeseman JA, Hamby KM, Speck SH, Larsen CP, Kirk AD, Kean LS. Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection. Plos One. 8: e71221. PMID 23940724 DOI: 10.1371/Journal.Pone.0071221 |
0.442 |
|
2013 |
Liang X, Crepeau RL, Zhang W, Speck SH, Usherwood EJ. CD4 and CD8 T cells directly recognize murine gammaherpesvirus 68-immortalized cells and prevent tumor outgrowth. Journal of Virology. 87: 6051-4. PMID 23514885 DOI: 10.1128/Jvi.00375-13 |
0.414 |
|
2013 |
Krug LT, Evans AG, Gargano LM, Paden CR, Speck SH. The absence of M1 leads to increased establishment of murine gammaherpesvirus 68 latency in IgD-negative B cells. Journal of Virology. 87: 3597-604. PMID 23302876 DOI: 10.1128/Jvi.01953-12 |
0.5 |
|
2012 |
Stahl JA, Paden CR, Chavan SS, MacLeod V, Edmondson RD, Speck SH, Forrest JC. Amplification of JNK signaling is necessary to complete the murine gammaherpesvirus 68 lytic replication cycle. Journal of Virology. 86: 13253-62. PMID 23015701 DOI: 10.1128/Jvi.01432-12 |
0.464 |
|
2012 |
Paden CR, Forrest JC, Tibbetts SA, Speck SH. Unbiased mutagenesis of MHV68 LANA reveals a DNA-binding domain required for LANA function in vitro and in vivo. Plos Pathogens. 8: e1002906. PMID 22969427 DOI: 10.1371/Journal.Ppat.1002906 |
0.409 |
|
2012 |
Gray KS, Collins CM, Speck SH. Characterization of omental immune aggregates during establishment of a latent gammaherpesvirus infection. Plos One. 7: e43196. PMID 22952645 DOI: 10.1371/Journal.Pone.0043196 |
0.509 |
|
2012 |
Collins CM, Speck SH. Tracking murine gammaherpesvirus 68 infection of germinal center B cells in vivo. Plos One. 7: e33230. PMID 22427999 DOI: 10.1371/Journal.Pone.0033230 |
0.532 |
|
2011 |
Liang X, Paden CR, Morales FM, Powers RP, Jacob J, Speck SH. Murine gamma-herpesvirus immortalization of fetal liver-derived B cells requires both the viral cyclin D homolog and latency-associated nuclear antigen. Plos Pathogens. 7: e1002220. PMID 21931547 DOI: 10.1371/Journal.Ppat.1002220 |
0.594 |
|
2011 |
Barton E, Mandal P, Speck SH. Pathogenesis and host control of gammaherpesviruses: lessons from the mouse. Annual Review of Immunology. 29: 351-97. PMID 21219186 DOI: 10.1146/Annurev-Immunol-072710-081639 |
0.528 |
|
2011 |
Herskowitz JH, Jacoby MA, Speck SH. The murine gammaherpesvirus 68 M2 gene is required for efficient reactivation from latently infected B cells (Journal of Virology (2005) 79, 4, (2261-2273)) Journal of Virology. 85: 3041. DOI: 10.1128/JVI.00066-11 |
0.702 |
|
2010 |
Speck SH, Ganem D. Viral latency and its regulation: lessons from the gamma-herpesviruses. Cell Host & Microbe. 8: 100-15. PMID 20638646 DOI: 10.1016/J.Chom.2010.06.014 |
0.485 |
|
2010 |
Krug LT, Torres-González E, Qin Q, Sorescu D, Rojas M, Stecenko A, Speck SH, Mora AL. Inhibition of NF-kappaB signaling reduces virus load and gammaherpesvirus-induced pulmonary fibrosis. The American Journal of Pathology. 177: 608-21. PMID 20566741 DOI: 10.2353/Ajpath.2010.091122 |
0.456 |
|
2010 |
Paden CR, Forrest JC, Moorman NJ, Speck SH. Murine gammaherpesvirus 68 LANA is essential for virus reactivation from splenocytes but not long-term carriage of viral genome. Journal of Virology. 84: 7214-24. PMID 20444892 DOI: 10.1128/Jvi.00133-10 |
0.526 |
|
2010 |
Gray KS, Forrest JC, Speck SH. The de novo methyltransferases DNMT3a and DNMT3b target the murine gammaherpesvirus immediate-early gene 50 promoter during establishment of latency. Journal of Virology. 84: 4946-59. PMID 20200245 DOI: 10.1128/Jvi.00060-10 |
0.558 |
|
2010 |
Siegel AM, Rangaswamy US, Napier RJ, Speck SH. Blimp-1-dependent plasma cell differentiation is required for efficient maintenance of murine gammaherpesvirus latency and antiviral antibody responses. Journal of Virology. 84: 674-85. PMID 19889763 DOI: 10.1128/Jvi.01306-09 |
0.543 |
|
2010 |
Beus J, Hamby K, Kirk AD, Larsen CP, Speck SH, Kean L. Identification of a Costimulation Blockade Resistant Mechanism of Bone Marrow Allograft Rejection Induced by Infection with a Murine EBV Homologue. Blood. 116: 1461-1461. DOI: 10.1182/Blood.V116.21.1461.1461 |
0.45 |
|
2009 |
Liang X, Collins CM, Mendel JB, Iwakoshi NN, Speck SH. Gammaherpesvirus-driven plasma cell differentiation regulates virus reactivation from latently infected B lymphocytes. Plos Pathogens. 5: e1000677. PMID 19956661 DOI: 10.1371/Journal.Ppat.1000677 |
0.59 |
|
2009 |
Collins CM, Boss JM, Speck SH. Identification of infected B-cell populations by using a recombinant murine gammaherpesvirus 68 expressing a fluorescent protein. Journal of Virology. 83: 6484-93. PMID 19386718 DOI: 10.1128/Jvi.00297-09 |
0.58 |
|
2009 |
Krug LT, Collins CM, Gargano LM, Speck SH. NF-kappaB p50 plays distinct roles in the establishment and control of murine gammaherpesvirus 68 latency. Journal of Virology. 83: 4732-48. PMID 19264770 DOI: 10.1128/Jvi.00111-09 |
0.503 |
|
2009 |
Gargano LM, Forrest JC, Speck SH. Signaling through Toll-like receptors induces murine gammaherpesvirus 68 reactivation in vivo. Journal of Virology. 83: 1474-82. PMID 19019960 DOI: 10.1128/Jvi.01717-08 |
0.52 |
|
2009 |
Gray KS, Allen RD, Farrell ML, Forrest JC, Speck SH. Alternatively initiated gene 50/RTA transcripts expressed during murine and human gammaherpesvirus reactivation from latency. Journal of Virology. 83: 314-28. PMID 18971285 DOI: 10.1128/Jvi.01444-08 |
0.611 |
|
2008 |
Forrest JC, Speck SH. Establishment of B-cell lines latently infected with reactivation-competent murine gammaherpesvirus 68 provides evidence for viral alteration of a DNA damage-signaling cascade. Journal of Virology. 82: 7688-99. PMID 18495760 DOI: 10.1128/Jvi.02689-07 |
0.53 |
|
2008 |
DeZalia M, Speck SH. Identification of closely spaced but distinct transcription initiation sites for the murine gammaherpesvirus 68 latency-associated M2 gene. Journal of Virology. 82: 7411-21. PMID 18480430 DOI: 10.1128/Jvi.00651-08 |
0.44 |
|
2008 |
Siegel AM, Herskowitz JH, Speck SH. The MHV68 M2 protein drives IL-10 dependent B cell proliferation and differentiation. Plos Pathogens. 4: e1000039. PMID 18389062 DOI: 10.1371/Journal.Ppat.1000039 |
0.418 |
|
2008 |
Evans AG, Moser JM, Krug LT, Pozharskaya V, Mora AL, Speck SH. A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology. The Journal of Experimental Medicine. 205: 669-84. PMID 18332178 DOI: 10.1084/Jem.20071135 |
0.476 |
|
2008 |
Stapler D, Lee ED, Selvaraj SA, Evans AG, Kean LS, Speck SH, Larsen CP, Gangappa S. Expansion of effector memory TCR Vbeta4+ CD8+ T cells is associated with latent infection-mediated resistance to transplantation tolerance. Journal of Immunology (Baltimore, Md. : 1950). 180: 3190-200. PMID 18292543 DOI: 10.4049/Jimmunol.180.5.3190 |
0.507 |
|
2008 |
Gargano LM, Moser JM, Speck SH. Role for MyD88 signaling in murine gammaherpesvirus 68 latency. Journal of Virology. 82: 3853-63. PMID 18256152 DOI: 10.1128/Jvi.02577-07 |
0.449 |
|
2008 |
Herskowitz JH, Siegel AM, Jacoby MA, Speck SH. Systematic mutagenesis of the murine gammaherpesvirus 68 M2 protein identifies domains important for chronic infection. Journal of Virology. 82: 3295-310. PMID 18234799 DOI: 10.1128/Jvi.02234-07 |
0.704 |
|
2007 |
Forrest JC, Paden CR, Allen RD, Collins J, Speck SH. ORF73-null murine gammaherpesvirus 68 reveals roles for mLANA and p53 in virus replication. Journal of Virology. 81: 11957-71. PMID 17699571 DOI: 10.1128/Jvi.00111-07 |
0.543 |
|
2007 |
Allen RD, DeZalia MN, Speck SH. Identification of an Rta responsive promoter involved in driving gammaHV68 v-cyclin expression during virus replication. Virology. 365: 250-9. PMID 17477952 DOI: 10.1016/J.Virol.2007.03.021 |
0.516 |
|
2007 |
Mora AL, Torres-González E, Rojas M, Xu J, Ritzenthaler J, Speck SH, Roman J, Brigham K, Stecenko A. Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice. American Journal of Respiratory and Critical Care Medicine. 175: 1139-50. PMID 17363768 DOI: 10.1164/Rccm.200610-1426Oc |
0.363 |
|
2007 |
Krug LT, Moser JM, Dickerson SM, Speck SH. Inhibition of NF-kappaB activation in vivo impairs establishment of gammaherpesvirus latency. Plos Pathogens. 3: e11. PMID 17257062 DOI: 10.1371/Journal.Ppat.0030011 |
0.537 |
|
2006 |
Upton JW, Speck SH. Evidence for CDK-dependent and CDK-independent functions of the murine gammaherpesvirus 68 v-cyclin. Journal of Virology. 80: 11946-59. PMID 17005668 DOI: 10.1128/Jvi.01722-06 |
0.469 |
|
2006 |
McClellan KB, Gangappa S, Speck SH, Virgin HW. Antibody-independent control of gamma-herpesvirus latency via B cell induction of anti-viral T cell responses. Plos Pathogens. 2: e58. PMID 16789842 DOI: 10.1371/Journal.Ppat.0020058 |
0.511 |
|
2006 |
Kersh EN, Fitzpatrick DR, Murali-Krishna K, Shires J, Speck SH, Boss JM, Ahmed R. Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 4083-93. PMID 16547244 DOI: 10.4049/Jimmunol.176.7.4083 |
0.406 |
|
2006 |
Allen RD, Dickerson S, Speck SH. Identification of spliced gammaherpesvirus 68 LANA and v-cyclin transcripts and analysis of their expression in vivo during latent infection Journal of Virology. 80: 2055-2062. PMID 16439562 DOI: 10.1128/Jvi.80.4.2055-2062.2006 |
0.546 |
|
2006 |
Moser JM, Farrell ML, Krug LT, Upton JW, Speck SH. A gammaherpesvirus 68 gene 50 null mutant establishes long-term latency in the lung but fails to vaccinate against a wild-type virus challenge. Journal of Virology. 80: 1592-8. PMID 16415035 DOI: 10.1128/Jvi.80.3.1592-1598.2006 |
0.563 |
|
2006 |
Evans AG, Moorman NJ, Willer DO, Speck SH. The M4 gene of gammaHV68 encodes a secreted glycoprotein and is required for the efficient establishment of splenic latency. Virology. 344: 520-31. PMID 16185740 DOI: 10.1016/J.Virol.2005.08.020 |
0.495 |
|
2005 |
Tarakanova VL, Suarez F, Tibbetts SA, Jacoby MA, Weck KE, Hess JL, Speck SH, Virgin HW. Murine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient mice. Journal of Virology. 79: 14668-79. PMID 16282467 DOI: 10.1128/Jvi.79.23.14668-14679.2005 |
0.714 |
|
2005 |
Loh J, Huang Q, Petros AM, Nettesheim D, van Dyk LF, Labrada L, Speck SH, Levine B, Olejniczak ET, Virgin HW. A surface groove essential for viral Bcl-2 function during chronic infection in vivo. Plos Pathogens. 1: e10. PMID 16201011 DOI: 10.1371/Journal.Ppat.0010010 |
0.345 |
|
2005 |
Upton JW, van Dyk LF, Speck SH. Characterization of murine gammaherpesvirus 68 v-cyclin interactions with cellular cdks. Virology. 341: 271-83. PMID 16102793 DOI: 10.1016/J.Virol.2005.07.014 |
0.356 |
|
2005 |
Moser JM, Upton JW, Allen RD, Wilson CB, Speck SH. Role of B-cell proliferation in the establishment of gammaherpesvirus latency. Journal of Virology. 79: 9480-91. PMID 16014911 DOI: 10.1128/Jvi.79.15.9480-9491.2005 |
0.574 |
|
2005 |
Moser JM, Upton JW, Gray KS, Speck SH. Ex vivo stimulation of B cells latently infected with gammaherpesvirus 68 triggers reactivation from latency. Journal of Virology. 79: 5227-31. PMID 15795307 DOI: 10.1128/Jvi.79.8.5227-5231.2005 |
0.565 |
|
2005 |
Mora AL, Woods CR, Garcia A, Xu J, Rojas M, Speck SH, Roman J, Brigham KL, Stecenko AA. Lung infection with gamma-herpesvirus induces progressive pulmonary fibrosis in Th2-biased mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L711-21. PMID 15734789 DOI: 10.1152/Ajplung.00007.2005 |
0.378 |
|
2005 |
Willer DO, Speck SH. Establishment and maintenance of long-term murine gammaherpesvirus 68 latency in B cells in the absence of CD40. Journal of Virology. 79: 2891-9. PMID 15709008 DOI: 10.1128/Jvi.79.5.2891-2899.2005 |
0.505 |
|
2005 |
Pavlova I, Lin CY, Speck SH. Murine gammaherpesvirus 68 Rta-dependent activation of the gene 57 promoter. Virology. 333: 169-79. PMID 15708602 DOI: 10.1016/J.Virol.2004.12.021 |
0.711 |
|
2005 |
Braaten DC, Sparks-Thissen RL, Kreher S, Speck SH, Virgin HW. An optimized CD8+ T-cell response controls productive and latent gammaherpesvirus infection. Journal of Virology. 79: 2573-83. PMID 15681457 DOI: 10.1128/JVI.79.4.2573-2583.2005 |
0.34 |
|
2005 |
Herskowitz JH, Herskowitz J, Jacoby MA, Speck SH. The murine gammaherpesvirus 68 M2 gene is required for efficient reactivation from latently infected B cells. Journal of Virology. 79: 2261-73. PMID 15681428 DOI: 10.1128/Jvi.79.4.2261-2273.2005 |
0.749 |
|
2004 |
Elliott J, Goodhew EB, Krug LT, Shakhnovsky N, Yoo L, Speck SH. Variable methylation of the Epstein-Barr virus Wp EBNA gene promoter in B-lymphoblastoid cell lines. Journal of Virology. 78: 14062-5. PMID 15564516 DOI: 10.1128/Jvi.78.24.14062-14065.2004 |
0.8 |
|
2004 |
Moorman NJ, Lin CY, Speck SH. Identification of candidate gammaherpesvirus 68 genes required for virus replication by signature-tagged transposon mutagenesis. Journal of Virology. 78: 10282-90. PMID 15367594 DOI: 10.1128/Jvi.78.19.10282-10290.2004 |
0.483 |
|
2004 |
Sparks-Thissen RL, Braaten DC, Kreher S, Speck SH, Virgin HW. An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection. Journal of Virology. 78: 6827-35. PMID 15194758 DOI: 10.1128/JVI.78.13.6827-6835.2004 |
0.326 |
|
2003 |
Moorman NJ, Willer DO, Speck SH. The gammaherpesvirus 68 latency-associated nuclear antigen homolog is critical for the establishment of splenic latency. Journal of Virology. 77: 10295-303. PMID 12970414 DOI: 10.1128/Jvi.77.19.10295-10303.2003 |
0.557 |
|
2003 |
Willer DO, Speck SH. Long-term latent murine Gammaherpesvirus 68 infection is preferentially found within the surface immunoglobulin D-negative subset of splenic B cells in vivo. Journal of Virology. 77: 8310-21. PMID 12857900 DOI: 10.1128/Jvi.77.15.8310-8321.2003 |
0.51 |
|
2003 |
Tibbetts SA, Loh J, Van Berkel V, McClellan JS, Jacoby MA, Kapadia SB, Speck SH, Virgin HW. Establishment and maintenance of gammaherpesvirus latency are independent of infective dose and route of infection. Journal of Virology. 77: 7696-701. PMID 12805472 DOI: 10.1128/Jvi.77.13.7696-7701.2003 |
0.692 |
|
2003 |
Liu P, Speck SH. Synergistic autoactivation of the Epstein-Barr virus immediate-early BRLF1 promoter by Rta and Zta. Virology. 310: 199-206. PMID 12781707 DOI: 10.1016/S0042-6822(03)00145-4 |
0.503 |
|
2003 |
Pavlova IV, Virgin HW, Speck SH. Disruption of gammaherpesvirus 68 gene 50 demonstrates that Rta is essential for virus replication. Journal of Virology. 77: 5731-9. PMID 12719566 DOI: 10.1128/Jvi.77.10.5731-5739.2003 |
0.711 |
|
2003 |
van Dyk LF, Virgin HW, Speck SH. Maintenance of gammaherpesvirus latency requires viral cyclin in the absence of B lymphocytes. Journal of Virology. 77: 5118-26. PMID 12692214 DOI: 10.1128/Jvi.77.9.5118-5126.2003 |
0.539 |
|
2003 |
Moorman NJ, Virgin HW, Speck SH. Disruption of the gene encoding the gammaHV68 v-GPCR leads to decreased efficiency of reactivation from latency. Virology. 307: 179-90. PMID 12667789 DOI: 10.1016/S0042-6822(02)00023-5 |
0.533 |
|
2002 |
Yoo LI, Woloszynek J, Templeton S, Speck SH. Deletion of Epstein-Barr virus regulatory sequences upstream of the EBNA gene promoter Wp1 is unfavorable for B-Cell immortalization. Journal of Virology. 76: 11763-9. PMID 12388739 DOI: 10.1128/Jvi.76.22.11763-11769.2002 |
0.789 |
|
2002 |
Gangappa S, Kapadia SB, Speck SH, Virgin HW. Antibody to a lytic cycle viral protein decreases gammaherpesvirus latency in B-cell-deficient mice. Journal of Virology. 76: 11460-8. PMID 12388707 DOI: 10.1128/Jvi.76.22.11460-11468.2002 |
0.529 |
|
2002 |
Speck SH. EBV framed in Burkitt lymphoma. Nature Medicine. 8: 1086-7. PMID 12357244 DOI: 10.1038/Nm1002-1086 |
0.482 |
|
2002 |
Kapadia SB, Levine B, Speck SH, Virgin HW. Critical role of complement and viral evasion of complement in acute, persistent, and latent gamma-herpesvirus infection. Immunity. 17: 143-55. PMID 12196286 DOI: 10.1016/S1074-7613(02)00369-2 |
0.436 |
|
2002 |
Paulson EJ, Fingeroth JD, Yates JL, Speck SH. Methylation of the EBV genome and establishment of restricted latency in low-passage EBV-infected 293 epithelial cells. Virology. 299: 109-21. PMID 12167346 DOI: 10.1006/Viro.2002.1457 |
0.51 |
|
2002 |
Tibbetts SA, van Dyk LF, Speck SH, Virgin HW. Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus. Journal of Virology. 76: 7125-32. PMID 12072512 DOI: 10.1128/JVI.76.14.7125-7132.2002 |
0.383 |
|
2002 |
Clambey ET, Virgin HW, Speck SH. Characterization of a spontaneous 9.5-kilobase-deletion mutant of murine gammaherpesvirus 68 reveals tissue-specific genetic requirements for latency. Journal of Virology. 76: 6532-44. PMID 12050366 DOI: 10.1128/Jvi.76.13.6532-6544.2002 |
0.477 |
|
2002 |
Gangappa S, van Dyk LF, Jewett TJ, Speck SH, Virgin HW. Identification of the in vivo role of a viral bcl-2. The Journal of Experimental Medicine. 195: 931-40. PMID 11927636 DOI: 10.1084/Jem.20011825 |
0.491 |
|
2002 |
van Berkel V, Levine B, Kapadia SB, Goldman JE, Speck SH, Virgin HW. Critical role for a high-affinity chemokine-binding protein in gamma-herpesvirus-induced lethal meningitis. The Journal of Clinical Investigation. 109: 905-14. PMID 11927617 DOI: 10.1172/Jci14358 |
0.427 |
|
2002 |
Jacoby MA, Virgin HW, Speck SH. Disruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation. Journal of Virology. 76: 1790-801. PMID 11799175 DOI: 10.1128/Jvi.76.4.1790-1801.2002 |
0.711 |
|
2001 |
Dal Canto AJ, Swanson PE, O'Guin AK, Speck SH, Virgin HW. IFN-γ action in the media of the great elastic arteries, a novel immunoprivileged site Journal of Clinical Investigation. 107. PMID 11160143 DOI: 10.1172/Jci11540 |
0.427 |
|
2000 |
Dal Canto AJ, Virgin IV HW, Speck SH. Ongoing viral replication is required for gammaherpesvirus 68-Induced vascular damage Journal of Virology. 74: 11304-11310. PMID 11070030 DOI: 10.1128/Jvi.74.23.11304-11310.2000 |
0.429 |
|
2000 |
Yoo L, Speck SH. Determining the role of the Epstein-Barr virus Cp EBNA2-dependent enhancer during the establishment of latency by using mutant and wild-type viruses recovered from cottontop marmoset lymphoblastoid cell lines Journal of Virology. 74: 11115-11120. PMID 11070007 DOI: 10.1128/Jvi.74.23.11115-11120.2000 |
0.828 |
|
2000 |
Van Dyk LF, Virgin IV HW, Speck SH. The murine gammaherpesvirus 68 v-cyclin is a critical regulator of reactivation from latency Journal of Virology. 74: 7451-7461. PMID 10906198 DOI: 10.1128/JVI.74.16.7451-7461.2000 |
0.375 |
|
2000 |
Kung C, Pingel JT, Heikinheimo M, Klemola T, Varkila K, Yoo LI, Vuopala K, Poyhonen M, Uhari M, Rogers M, Speck SH, Chatila T, Thomas ML. Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease. Nature Medicine. 6: 343-5. PMID 10700239 DOI: 10.1038/73208 |
0.758 |
|
2000 |
Liu S, Pavlova IV, Virgin HW, Speck SH. Characterization of gammaherpesvirus 68 gene 50 transcription. Journal of Virology. 74: 2029-37. PMID 10644377 DOI: 10.1128/Jvi.74.4.2029-2037.2000 |
0.622 |
|
2000 |
Clambey ET, Virgin IV HW, Speck SH. Disruption of the murine gammaherpesvirus 68 M1 open reading frame leads to enhanced reactivation from latency Journal of Virology. 74: 1973-1984. PMID 10644370 DOI: 10.1128/Jvi.74.4.1973-1984.2000 |
0.467 |
|
1999 |
Paulson EJ, Speck SH. Differential methylation of Epstein-Barr virus latency promoters facilitates viral persistence in healthy seropositive individuals Journal of Virology. 73: 9959-9968. PMID 10559309 DOI: 10.1128/Jvi.73.12.9959-9968.1999 |
0.516 |
|
1999 |
Speck SH, Virgin IV HW. Host and viral genetics of chronic infection: A mouse model of gamma- herpesvirus pathogenesis Current Opinion in Microbiology. 2: 403-409. PMID 10458986 DOI: 10.1016/S1369-5274(99)80071-X |
0.316 |
|
1999 |
Virgin IV HW, Speck SH. Unraveling immunity to γ-herpesviruses: A new model for understanding the role of immunity in chronic virus infection Current Opinion in Immunology. 11: 371-379. PMID 10448140 DOI: 10.1016/S0952-7915(99)80063-6 |
0.462 |
|
1999 |
Kapadia SB, Molina H, Van Berkel V, Speck SH, Virgin IV HW. Murine gammaherpesvirus 68 encodes a functional regulator of complement activation Journal of Virology. 73: 7658-7670. PMID 10438856 DOI: 10.1128/Jvi.73.9.7658-7670.1999 |
0.472 |
|
1999 |
van Dyk LF, Hess JL, Katz JD, Jacoby M, Speck SH, Virgin HW IV. The murine gammaherpesvirus 68 v-cyclin gene is an oncogene that promotes cell cycle progression in primary lymphocytes. Journal of Virology. 73: 5110-22. PMID 10233974 DOI: 10.1128/Jvi.73.6.5110-5122.1999 |
0.687 |
|
1999 |
Weck KE, Kim SS, Virgin IV HW, Speck SH. B cells regulate murine gammaherpesvirus 68 latency Journal of Virology. 73: 4651-4661. PMID 10233924 |
0.405 |
|
1999 |
Van Berkel V, Preiter K, Virgin IV HW, Speck SH. Identification and initial characterization of the murine gammaherpesvirus 68 gene M3, encoding an abundantly secreted protein Journal of Virology. 73: 4524-4529. PMID 10196360 DOI: 10.1128/Jvi.73.5.4524-4529.1999 |
0.383 |
|
1999 |
Weck KE, Kim SS, Virgin IV HW, Speck SH. Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells Journal of Virology. 73: 3273-3283. PMID 10074181 |
0.346 |
|
1999 |
Virgin IV HW, Presti RM, Li XY, Liu C, Speck SH. Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice Journal of Virology. 73: 2321-2332. PMID 9971815 DOI: 10.1128/Jvi.73.3.2321-2332.1999 |
0.544 |
|
1999 |
Kapadia SB, Molina H, van Berkel V, Speck SH, Virgin HW. Murine Gammaherpesvirus 68 Encodes a Functional Regulator of Complement Activation Journal of Virology. 73: 7658-7670. DOI: 10.1128/jvi.73.9.7658-7670.1999 |
0.381 |
|
1998 |
Liu P, Liu S, Speck SH. Identification of a negative cis element within the ZII domain of the Epstein-Barr virus lytic switch BZLF1 gene promoter Journal of Virology. 72: 8230-8239. PMID 9733866 DOI: 10.1128/Jvi.72.10.8230-8239.1998 |
0.403 |
|
1997 |
Weck KE, Dal Canto AJ, Gould JD, O'Guin AK, Roth KA, Saffitz JE, Speck SH, Virgin HW. Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease. Nature Medicine. 3: 1346-53. PMID 9396604 DOI: 10.1038/nm1297-1346 |
0.328 |
|
1997 |
Yoo LI, Mooney M, Puglielli MT, Speck SH. B-cell lines immortalized with an Epstein-Barr virus mutant lacking the Cp EBNA2 enhancer are biased toward utilization of the oriP-proximal EBNA gene promoter Wp1. Journal of Virology. 71: 9134-42. PMID 9371570 DOI: 10.1128/Jvi.71.12.9134-9142.1997 |
0.813 |
|
1997 |
Speck SH, Chatlla T, Flemington E. Reactivation of Epstein-Barr virus: Regulation and function of the BZLF1 gene Trends in Microbiology. 5: 399-405. PMID 9351176 DOI: 10.1016/S0966-842X(97)01129-3 |
0.465 |
|
1997 |
Chatila T, Ho N, Liu P, Liu S, Mosialos G, Kieff E, Speck SH. The Epstein-Barr virus-induced Ca2+/calmodulin-dependent kinase type IV/Gr promotes a Ca(2+)-dependent switch from latency to viral replication. Journal of Virology. 71: 6560-7. PMID 9261377 DOI: 10.1128/Jvi.71.9.6560-6567.1997 |
0.372 |
|
1997 |
Virgin HW, Latreille P, Wamsley P, Hallsworth K, Weck KE, Dal Canto AJ, Speck SH. Complete sequence and genomic analysis of murine gammaherpesvirus 68. Journal of Virology. 71: 5894-904. PMID 9223479 |
0.306 |
|
1997 |
Schaefer BC, Paulson E, Strominger JL, Speck SH. Constitutive activation of epstein-barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency Molecular and Cellular Biology. 17: 873-886. PMID 9001242 DOI: 10.1128/Mcb.17.2.873 |
0.399 |
|
1997 |
Puglielli MT, Desai N, Speck SH. Regulation of EBNA gene transcription in lymphoblastoid cell lines: Characterization of sequences downstream of BCR2 (Cp) Journal of Virology. 71: 120-128. PMID 8985330 |
0.366 |
|
1996 |
Schaefer BC, Strominger JL, Speck SH. A simple reverse transcriptase PCR assay to distinguish EBNA1 gene transcripts associated with type I and II latency from those arising during induction of the viral lytic cycle Journal of Virology. 70: 8204-8208. PMID 8892954 DOI: 10.1128/Jvi.70.11.8204-8208.1996 |
0.528 |
|
1996 |
Weck KE, Barkon ML, Yoo LI, Speck SH, Virgin HW IV. Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68. Journal of Virology. 70: 6775-80. PMID 8794315 DOI: 10.1128/Jvi.70.10.6775-6780.1996 |
0.811 |
|
1996 |
Puglielli MT, Woisetschlaeger M, Speck SH. oriP is essential for EBNA gene promoter activity in Epstein-Barr virus-immortalized lymphoblastoid cell lines Journal of Virology. 70: 5758-5768. PMID 8709191 DOI: 10.1128/Jvi.70.9.5758-5768.1996 |
0.488 |
|
1996 |
Schlager S, Speck SH, Woisetschlger M. Transcription of the Epstein-Barr virus nuclear antigen 1 (EBNA1) gene occurs before induction of the BCR2 (Cp) EBNA gene promoter during the initial stages of infection in B cells Journal of Virology. 70: 3561-3570. PMID 8648690 |
0.542 |
|
1995 |
Schaefer BC, Strominger JL, Speck SH. The Epstein-Barr virus BamHI F promoter is an early lytic promoter: Lack of correlation with EBNA 1 gene transcription in group 1 Burkitt's lymphoma cell lines Journal of Virology. 69: 5039-5047. PMID 7609074 DOI: 10.1128/Jvi.69.8.5039-5047.1995 |
0.468 |
|
1995 |
Goldfeld AE, Liu P, Liu S, Flemington EK, Strominger JL, Speck SH. Cyclosporin A and FK506 block induction of the Epstein-Barr virus lytic cycle by anti-immunoglobulin Virology. 209: 225-229. PMID 7538254 DOI: 10.1006/Viro.1995.1247 |
0.5 |
|
1995 |
Schaefer BC, Strominger JL, Speck SH. Redefining the Epstein-Barr virus-encoded nuclear antigen EBNA-1 gene promoter and transcription initiation site in group I Burkitt lymphoma cell lines Proceedings of the National Academy of Sciences of the United States of America. 92: 10565-10569. PMID 7479841 DOI: 10.1073/Pnas.92.23.10565 |
0.5 |
|
1995 |
Schaefer BC, Strominger JL, Speck SH. The Epstein-Barr virus BamHI F promoter is an early lytic promoter: lack of correlation with EBNA 1 gene transcription in group 1 Burkitt's lymphoma cell lines. Journal of Virology. 69: 5039-5047. DOI: 10.1128/jvi.69.8.5039-5047.1995 |
0.349 |
|
1994 |
Daibata M, Speck SH, Mulder C, Sairenji T. Regulation of the BZLF1 promoter of Epstein-Barr virus by second messengers in anti-immunoglobulin-treated B cells Virology. 198: 446-454. PMID 8291228 DOI: 10.1006/Viro.1994.1056 |
0.396 |
|
1994 |
Flemington EK, Lytle JP, Cayrol C, Borras AM, Speck SH. DNA-binding-defective mutants of the Epstein-Barr virus lytic switch activator Zta transactivate with altered specificities Molecular and Cellular Biology. 14: 3041-3052. PMID 8164660 DOI: 10.1128/Mcb.14.5.3041 |
0.329 |
|
1993 |
Flemington EK, Speck SH, Kaelin WG. E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product Proceedings of the National Academy of Sciences of the United States of America. 90: 6914-6918. PMID 8346196 DOI: 10.1073/Pnas.90.15.6914 |
0.388 |
|
1992 |
Yandava CN, Speck SH. Characterization of the deletion and rearrangement in the BamHI C region of the X50-7 epstein-barr virus genome, a mutant viral strain which exhibits constitutive BamHI W promoter activity Journal of Virology. 66: 5646-5650. PMID 1323716 |
0.478 |
|
1992 |
Jin XW, Speck SH. Identification of critical cis elements involved in mediating Epstein-Barr virus nuclear antigen 2-dependent activity of an enhancer located upstream of the viral BamHI C prompter Journal of Virology. 66: 2846-2852. PMID 1313905 |
0.434 |
|
1992 |
Goldfeld AE, Flemington EK, Boussiotis VA, Theodos CM, Titus RG, Strominger JL, Speck SH. Transcription of the tumor necrosis factor α gene is rapidly induced by anti-immunoglobulin and blocked by cyclosporin A and FK506 in human B cells Proceedings of the National Academy of Sciences of the United States of America. 89: 12198-12201. PMID 1281550 DOI: 10.1073/Pnas.89.24.12198 |
0.383 |
|
1991 |
Woisetschlaeger M, Jin XW, Yandava CN, Furmanski LA, Strominger JL, Speck SH. Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection Proceedings of the National Academy of Sciences of the United States of America. 88: 3942-3946. PMID 1850841 DOI: 10.1073/Pnas.88.9.3942 |
0.491 |
|
1991 |
Schaefer BC, Woisetschlaeger M, Strominger JL, Speck SH. Exclusive expression of Epstein-Barr virus nuclear antigen 1 in Burkitt lymphoma arises from a third promoter, distinct from the promoters used in latently infected lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 88: 6550-6554. PMID 1713681 DOI: 10.1073/Pnas.88.15.6550 |
0.407 |
|
1991 |
Flemington EK, Goldfeld AE, Speck SH. Efficient transcription of the Epstein-Barr virus immediate-early BZLF1 and BRLF1 genes requires protein synthesis Journal of Virology. 65: 7073-7077. PMID 1658397 DOI: 10.1128/Jvi.65.12.7073-7077.1991 |
0.491 |
|
1991 |
Rogers RP, Strominger JL, Speck SH. Epstein-barr virus in b lymphocytes: Viral gene expression and function in latency Advances in Cancer Research. 58: 1-26. PMID 1312289 DOI: 10.1016/S0065-230X(08)60288-2 |
0.453 |
|
1990 |
Flemington E, Speck SH. Epstein-Barr virus BZLF1 trans activator induces the promoter of a cellular cognate gene, c-fos Journal of Virology. 64: 4549-4552. PMID 2166830 DOI: 10.1128/Jvi.64.9.4549-4552.1990 |
0.346 |
|
1990 |
Rogers RP, Woisetschlaeger M, Speck SH. Alternative splicing dictates translational start in Epstein - Barr virus transcripts Embo Journal. 9: 2273-2277. PMID 2162768 |
0.371 |
|
1990 |
Woisetschlaeger M, Yandava CN, Furmanski LA, Strominger JL, Speck SH. Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 87: 1725-1729. PMID 2155423 DOI: 10.1073/Pnas.87.5.1725 |
0.593 |
|
1990 |
Flemington E, Speck SH. Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1 Journal of Virology. 64: 1227-1232. PMID 2154606 DOI: 10.1128/Jvi.64.3.1227-1232.1990 |
0.352 |
|
1990 |
Rogers RP, Speck SH. Bidirectional transcription of the Epstein-Barr virus major internal repeat Journal of Virology. 64: 2426-2429. PMID 1691315 |
0.432 |
|
1989 |
Woisetschlaeger M, Strominger JL, Speck SH. Mutually exclusive use of viral promoters in Epstein-Barr virus latently infected lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 86: 6498-6502. PMID 2549539 DOI: 10.1073/Pnas.86.17.6498 |
0.422 |
|
1989 |
Rooney C, Howe JG, Speck SH, Miller G. Influences of Burkitt's lymphoma and primary B cells on latent gene expression by the nonimmortalizing P3J-HR-1 strain of Epstein-Barr virus Journal of Virology. 63: 1531-1539. PMID 2538644 |
0.5 |
|
1988 |
Austin PJ, Flemington E, Naidu Yandava C, Strominger JL, Speck SH. Complex transcription of the Epstein-Barr virus BamHI fragment H rightward open reading frame 1 (BHRF1) in latently and lytically infected B lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 85: 3678-3682. PMID 2836854 DOI: 10.1073/Pnas.85.11.3678 |
0.448 |
|
1987 |
Quackenbush E, Clabby M, Gottesdiener KM, Barbosa J, Jones NH, Strominger JL, Speck S, Leiden JM. Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth. Proceedings of the National Academy of Sciences of the United States of America. 84: 6526-30. PMID 3476959 DOI: 10.1073/Pnas.84.18.6526 |
0.324 |
|
1987 |
Pfitzner AJ, Tsai EC, Strominger JL, Speck SH. Isolation and characterization of cDNA clones corresponding to transcripts from the BamHI H and F regions of the Epstein-Barr virus genome Journal of Virology. 61: 2902-2909. PMID 3039177 |
0.386 |
|
1987 |
Speck SH, Strominger JL. Epstein-Barr virus transformation Progress in Nucleic Acid Research and Molecular Biology. 34: 189-207. PMID 2830637 DOI: 10.1016/S0079-6603(08)60496-1 |
0.385 |
|
1987 |
Pfitzner AJ, Strominger JL, Speck SH. Characterization of a cDNA clone corresponding to a transcript from the Epstein-Barr virus BamHI M fragment: Evidence for overlapping mRNAs Journal of Virology. 61: 2943-2946. PMID 2441081 |
0.322 |
|
1987 |
Pfitzner AJ, Strominger JL, Speck SH. Characterization of a cDNA clone corresponding to a transcript from the Epstein-Barr virus BamHI M fragment: evidence for overlapping mRNAs. Journal of Virology. 61: 2943-2946. DOI: 10.1128/jvi.61.9.2943-2946.1987 |
0.305 |
|
1986 |
Speck SH, Pfizner A, Strominger JL. An Epstein-Barr virus transcript from a latently infected, growth-transformed B-cell line encodes a highly repetitive polypeptide Proceedings of the National Academy of Sciences of the United States of America. 83: 9298-9302. PMID 3025831 DOI: 10.1073/pnas.83.24.9298 |
0.401 |
|
1985 |
Speck SH, Strominger JL. Analysis of the transcript encoding the latent Epstein-Barr virus nuclear antigen I: A potentially polycistronic message generated by long-range splicing of several exons Proceedings of the National Academy of Sciences of the United States of America. 82: 8305-8309. PMID 3001694 DOI: 10.1073/Pnas.82.24.8305 |
0.488 |
|
1984 |
Cohen LK, Speck SH, Roberts BE, Strominger JL. Identification and mapping of polypeptides encoded by the P3HR-1 strain of Epstein-Barr virus Proceedings of the National Academy of Sciences of the United States of America. 81: 4183-4187. PMID 6330747 DOI: 10.1073/Pnas.81.13.4183 |
0.45 |
|
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