| Year |
Citation |
Score |
| 2023 |
Stepanov AV, Xie J, Zhu Q, Shen Z, Su W, Kuai L, Soll R, Rader C, Shaver G, Douthit L, Zhang D, Kalinin R, Fu X, Zhao Y, Qin T, ... ... Lerner RA, et al. Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells. Nature Biomedical Engineering. PMID 37798444 DOI: 10.1038/s41551-023-01102-5 |
0.503 |
|
| 2021 |
Qiang M, Ma P, Li Y, Liu H, Harding A, Min C, Wang F, Liu L, Yuan M, Ji Q, Tao P, Shi X, Li Z, Li T, Wang X, ... ... Lerner RA, et al. Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2102181. PMID 34716683 DOI: 10.1002/advs.202102181 |
0.386 |
|
| 2021 |
Lin CW, Zheng T, Grande G, Nanna AR, Rader C, Lerner RA. A new immunochemical strategy for triple-negative breast cancer therapy. Scientific Reports. 11: 14875. PMID 34290315 DOI: 10.1038/s41598-021-94230-4 |
0.505 |
|
| 2021 |
Shi X, Wan Y, Wang N, Xiang J, Wang T, Yang X, Wang J, Dong X, Dong L, Yan L, Li Y, Liu L, Hou S, Zhong Z, Wilson IA, ... ... Lerner RA, et al. Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms. Nature Communications. 12: 2547. PMID 33953162 DOI: 10.1038/s41467-021-22810-z |
0.312 |
|
| 2021 |
Lin CW, Lerner RA. Antibody Libraries as Tools to Discover Functional Antibodies and Receptor Pleiotropism. International Journal of Molecular Sciences. 22. PMID 33923551 DOI: 10.3390/ijms22084123 |
0.373 |
|
| 2020 |
Mokrushina YA, Golovin AV, Smirnov IV, Chatziefthimiou SD, Stepanova AV, Bobik TV, Zalevsky AO, Zlobin AS, Konovalov KA, Terekhov SS, Stepanov AV, Pipiya SO, Shamborant OG, Round E, Belogurov AA, ... ... Lerner RA, et al. Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers. Proceedings of the National Academy of Sciences of the United States of America. PMID 32859757 DOI: 10.1073/Pnas.2010317117 |
0.366 |
|
| 2020 |
Tao P, Kuang Y, Li Y, Li W, Gao Z, Liu L, Qiang M, Zha Z, Fan K, Ma P, Friedman JM, Yang G, Lerner RA. Selection of a Full Agonist Combinatorial Antibody that Rescues Leptin Deficiency In Vivo. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 2000818. PMID 32832353 DOI: 10.1002/Advs.202000818 |
0.445 |
|
| 2020 |
Kuang Y, Zorzi V, Buratto D, Ziraldo G, Mazzarda F, Peres C, Nardin C, Salvatore AM, Chiani F, Scavizzi F, Raspa M, Qiang M, Chu Y, Shi X, Li Y, ... ... Lerner RA, et al. A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice. Ebiomedicine. 102825. PMID 32553574 DOI: 10.1016/J.Ebiom.2020.102825 |
0.34 |
|
| 2020 |
Meng B, Lan K, Xie J, Lerner RA, Wilson IA, Yang B. Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 32467165 DOI: 10.1073/Pnas.1918844117 |
0.375 |
|
| 2020 |
Han KH, Arlian BM, Lin CW, Jin HY, Kang GH, Lee S, Lee PC, Lerner RA. Agonist Antibody Converts Stem Cells into Migrating Brown Adipocyte-Like Cells in Heart. Cells. 9. PMID 31968623 DOI: 10.3390/Cells9010256 |
0.326 |
|
| 2019 |
Lin CW, Xie J, Zhang D, Han KH, Grande G, Wu NC, Yang Z, Yea K, Lerner RA. Immunity against cancer cells may promote their proliferation and metastasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31871166 DOI: 10.1073/Pnas.1916833117 |
0.34 |
|
| 2019 |
Yang Z, Wan Y, Tao P, Qiang M, Dong X, Lin CW, Yang G, Zheng T, Lerner RA. A cell-cell interaction format for selection of high-affinity antibodies to membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 31285332 DOI: 10.1073/Pnas.1908571116 |
0.422 |
|
| 2019 |
Yea K, Jones TM, Jung D, Shin S, Arlian BM, Han KH, Zha Z, Kim MS, Oh YS, Zhang H, Lerner RA. An agonist antibody prefers relapsed AML for induction of cells that kill each other. Scientific Reports. 9: 3494. PMID 30837591 DOI: 10.1038/S41598-019-40087-7 |
0.393 |
|
| 2018 |
Stepanov AV, Markov OV, Chernikov IV, Gladkikh DV, Zhang H, Jones T, Sen'kova AV, Chernolovskaya EL, Zenkova MA, Kalinin RS, Rubtsova MP, Meleshko AN, Genkin DD, Belogurov AA, Xie J, ... ... Lerner RA, et al. Autocrine-based selection of ligands for personalized CAR-T therapy of lymphoma. Science Advances. 4: eaau4580. PMID 30443597 DOI: 10.1126/Sciadv.Aau4580 |
0.343 |
|
| 2018 |
Qiang M, Dong X, Zha Z, Zuo XK, Song XL, Zhao L, Yuan C, Huang C, Tao P, Hu Q, Li WG, Hu W, Li J, Nie Y, Buratto D, ... ... Lerner RA, et al. Selection of an ASIC1a-blocking combinatorial antibody that protects cells from ischemic death. Proceedings of the National Academy of Sciences of the United States of America. PMID 30042215 DOI: 10.1073/Pnas.1807233115 |
0.388 |
|
| 2018 |
Merkouris S, Barde YA, Binley KE, Allen ND, Stepanov AV, Wu NC, Grande G, Lin CW, Li M, Nan X, Chacon-Fernandez P, DiStefano PS, Lindsay RM, Lerner RA, Xie J. Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987039 DOI: 10.1073/Pnas.1806660115 |
0.397 |
|
| 2018 |
Zheng T, Xie J, Yang Z, Tao P, Shi B, Douthit L, Wu P, Lerner RA. Antibody selection using clonal cocultivation of and eukaryotic cells in miniecosystems. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915075 DOI: 10.1073/Pnas.1806718115 |
0.477 |
|
| 2018 |
Yang Z, Du M, Wang W, Xin X, Ma P, Zhang H, Lerner RA. Affinity maturation of an TpoR targeting antibody in full-length IgG form for enhanced agonist activity. Protein Engineering, Design & Selection : Peds. PMID 29474709 DOI: 10.1093/Protein/Gzy002 |
0.453 |
|
| 2018 |
Han KH, Arlian BM, Macauley MS, Paulson JC, Lerner RA. Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid β. Proceedings of the National Academy of Sciences of the United States of America. PMID 29295920 DOI: 10.1073/Pnas.1719259115 |
0.343 |
|
| 2017 |
Xu L, Carrer A, Zonta F, Qu Z, Ma P, Li S, Ceriani F, Buratto D, Crispino G, Zorzi V, Ziraldo G, Bruno F, Nardin C, Peres C, Mazzarda F, ... ... Lerner RA, et al. Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders. Frontiers in Molecular Neuroscience. 10: 298. PMID 29018324 DOI: 10.3389/Fnmol.2017.00298 |
0.465 |
|
| 2017 |
Lang S, Xie J, Zhu X, Wu NC, Lerner RA, Wilson IA. Antibody 27F3 Broadly Targets Influenza A Group 1 and 2 Hemagglutinins through a Further Variation in VH1-69 Antibody Orientation on the HA Stem. Cell Reports. 20: 2935-2943. PMID 28930686 DOI: 10.1016/J.Celrep.2017.08.084 |
0.399 |
|
| 2017 |
Blanchard JW, Xie J, El-Mecharrafie N, Gross S, Lee S, Lerner RA, Baldwin KK. Replacing reprogramming factors with antibodies selected from combinatorial antibody libraries. Nature Biotechnology. PMID 28892074 DOI: 10.1038/Nbt.3963 |
0.424 |
|
| 2017 |
Wu NC, Grande G, Turner HL, Ward AB, Xie J, Lerner RA, Wilson IA. In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity. Nature Communications. 8: 15371. PMID 28504265 DOI: 10.1038/Ncomms15371 |
0.34 |
|
| 2017 |
Xie J, Sok D, Wu NC, Zheng T, Zhang W, Burton DR, Lerner RA. Immunochemical engineering of cell surfaces to generate virus resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396429 DOI: 10.1073/Pnas.1702764114 |
0.388 |
|
| 2016 |
Smirnov IV, Golovin AV, Chatziefthimiou SD, Stepanova AV, Peng Y, Zolotareva OI, Belogurov AA, Kurkova IN, Ponomarenko NA, Wilmanns M, Blackburn GM, Gabibov AG, Lerner RA. Robotic QM/MM-driven maturation of antibody combining sites. Science Advances. 2: e1501695. PMID 27774510 DOI: 10.1126/Sciadv.1501695 |
0.38 |
|
| 2016 |
Lerner RA. Combinatorial antibody libraries: new advances, new immunological insights. Nature Reviews. Immunology. PMID 27374636 DOI: 10.1038/Nri.2016.67 |
0.482 |
|
| 2015 |
Lerner RA, Grover RK, Zhang H, Xie J, Han KH, Peng Y, Yea K. Antibodies from combinatorial libraries use functional receptor pleiotropism to regulate cell fates. Quarterly Reviews of Biophysics. 48: 389-94. PMID 26537396 DOI: 10.1017/S0033583515000049 |
0.39 |
|
| 2015 |
Yea K, Zhang H, Xie J, Jones TM, Lin CW, Francesconi W, Berton F, Fallahi M, Sauer K, Lerner RA. Agonist antibody that induces human malignant cells to kill one another. Proceedings of the National Academy of Sciences of the United States of America. PMID 26487683 DOI: 10.1073/Pnas.1519079112 |
0.346 |
|
| 2015 |
Han KH, Gonzalez-Quintial R, Peng Y, Baccala R, Theofilopoulos AN, Lerner RA. An agonist antibody that blocks autoimmunity by inducing anti-inflammatory macrophages. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26481307 DOI: 10.1096/Fj.15-281329 |
0.408 |
|
| 2015 |
Peng Y, Zeng W, Ye H, Han KH, Dharmarajan V, Novick S, Wilson IA, Griffin PR, Friedman JM, Lerner RA. A General Method for Insertion of Functional Proteins within Proteins via Combinatorial Selection of Permissive Junctions. Chemistry & Biology. 22: 1134-43. PMID 26278185 DOI: 10.1016/J.Chembiol.2015.07.011 |
0.301 |
|
| 2014 |
Lerner RA. Gerald Maurice Edelman. Proceedings of the National Academy of Sciences of the United States of America. 111: 10900-1. PMID 25049421 DOI: 10.1073/Pnas.1410861111 |
0.424 |
|
| 2014 |
Grover RK, Zhu X, Nieusma T, Jones T, Boero I, MacLeod AS, Mark A, Niessen S, Kim HJ, Kong L, Assad-Garcia N, Kwon K, Chesi M, Smider VV, Salomon DR, ... ... Lerner RA, et al. A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science (New York, N.Y.). 343: 656-61. PMID 24503852 DOI: 10.1126/Science.1246135 |
0.413 |
|
| 2014 |
Xie J, Yea K, Zhang H, Moldt B, He L, Zhu J, Lerner RA. Prevention of cell death by antibodies selected from intracellular combinatorial libraries. Chemistry & Biology. 21: 274-83. PMID 24440080 DOI: 10.1016/J.Chembiol.2013.12.006 |
0.426 |
|
| 2013 |
Yea K, Zhang H, Xie J, Jones TM, Yang G, Song BD, Lerner RA. Converting stem cells to dendritic cells by agonist antibodies from unbiased morphogenic selections. Proceedings of the National Academy of Sciences of the United States of America. 110: 14966-71. PMID 23980154 DOI: 10.1073/Pnas.1313671110 |
0.42 |
|
| 2013 |
Zhang H, Yea K, Xie J, Ruiz D, Wilson IA, Lerner RA. Selecting agonists from single cells infected with combinatorial antibody libraries. Chemistry & Biology. 20: 734-41. PMID 23706638 DOI: 10.1016/J.Chembiol.2013.04.012 |
0.443 |
|
| 2013 |
Xie J, Zhang H, Yea K, Lerner RA. Autocrine signaling based selection of combinatorial antibodies that transdifferentiate human stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 8099-104. PMID 23613575 DOI: 10.1073/Pnas.1306263110 |
0.426 |
|
| 2013 |
Goswami RK, Liu Y, Liu C, Lerner RA, Sinha SC. Synthesis and evaluation of the aldolase antibody-derived chemical-antibodies targeting α5β1 integrin. Molecular Pharmaceutics. 10: 538-43. PMID 23102054 DOI: 10.1021/Mp3004463 |
0.377 |
|
| 2012 |
Zhang H, Wilson IA, Lerner RA. Selection of antibodies that regulate phenotype from intracellular combinatorial antibody libraries. Proceedings of the National Academy of Sciences of the United States of America. 109: 15728-33. PMID 23019357 DOI: 10.1073/Pnas.1214275109 |
0.495 |
|
| 2012 |
Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, ... Lerner RA, et al. Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature. 489: 526-32. PMID 22982990 DOI: 10.1038/Nature11414 |
0.428 |
|
| 2011 |
Zhang H, Torkamani A, Jones TM, Ruiz DI, Pons J, Lerner RA. Phenotype-information-phenotype cycle for deconvolution of combinatorial antibody libraries selected against complex systems. Proceedings of the National Academy of Sciences of the United States of America. 108: 13456-61. PMID 21825149 DOI: 10.1073/Pnas.1111218108 |
0.397 |
|
| 2011 |
Goswami RK, Bajjuri KM, Forsyth JS, Das S, Hassenpflug W, Huang ZZ, Lerner RA, Felding-Habermann B, Sinha SC. Chemically programmed antibodies targeting multiple alpha(v) integrins and their effects on tumor-related functions in vitro. Bioconjugate Chemistry. 22: 1535-44. PMID 21774545 DOI: 10.1021/Bc2000879 |
0.315 |
|
| 2011 |
Gauba V, Grünewald J, Gorney V, Deaton LM, Kang M, Bursulaya B, Ou W, Lerner RA, Schmedt C, Geierstanger BH, Schultz PG, Ramirez-Montagut T. Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids. Proceedings of the National Academy of Sciences of the United States of America. 108: 12821-6. PMID 21768354 DOI: 10.1073/Pnas.1110042108 |
0.511 |
|
| 2011 |
Lerner RA. Rare antibodies from combinatorial libraries suggests an S.O.S. component of the human immunological repertoire. Molecular Biosystems. 7: 1004-12. PMID 21298133 DOI: 10.1039/C0Mb00310G |
0.452 |
|
| 2010 |
Doppalapudi VR, Huang J, Liu D, Jin P, Liu B, Li L, Desharnais J, Hagen C, Levin NJ, Shields MJ, Parish M, Murphy RE, Del Rosario J, Oates BD, Lai JY, ... ... Lerner RA, et al. Chemical generation of bispecific antibodies. Proceedings of the National Academy of Sciences of the United States of America. 107: 22611-6. PMID 21149738 DOI: 10.1073/Pnas.1016478108 |
0.477 |
|
| 2010 |
Kashyap AK, Steel J, Rubrum A, Estelles A, Briante R, Ilyushina NA, Xu L, Swale RE, Faynboym AM, Foreman PK, Horowitz M, Horowitz L, Webby R, Palese P, Lerner RA, et al. Protection from the 2009 H1N1 pandemic influenza by an antibody from combinatorial survivor-based libraries. Plos Pathogens. 6: e1000990. PMID 20628565 DOI: 10.1371/Journal.Ppat.1000990 |
0.314 |
|
| 2010 |
Xu L, Estellés A, Briante R, Kurtzman AL, Hannum CH, Kashyap AK, Horowitz L, Horowitz M, Bhatt RR, Lerner RA. Surrobodies with functional tails. Journal of Molecular Biology. 397: 352-60. PMID 20100493 DOI: 10.1016/J.Jmb.2010.01.036 |
0.378 |
|
| 2010 |
LI T, LERNER RA, JANDA KD. ChemInform Abstract: Antibody-Catalyzed Cationic Reactions: Rerouting of Chemical Transformations via Antibody Catalysis Cheminform. 28: no-no. DOI: 10.1002/chin.199727296 |
0.375 |
|
| 2010 |
PATTERSON JE, OLLMANN IR, CRAVATT BF, BOGER DL, WONG C, LERNER RA. ChemInform Abstract: Inhibition of Oleamide Hydrolase Catalyzed Hydrolysis of the Endogenous Sleep-Inducing Lipid cis-9-Octadecenamide. Cheminform. 27: no-no. DOI: 10.1002/chin.199640217 |
0.459 |
|
| 2010 |
BOGER DL, LERNER RA, CRAVATT BF. ChemInform Abstract: Synthesis of a Functionalized Rigid Bicyclo(2.2.1)heptane: A Useful Hapten for Eliciting Catalytic Antibodies. Cheminform. 26: no-no. DOI: 10.1002/chin.199511111 |
0.619 |
|
| 2010 |
SCHULTZ PG, LERNER RA. ChemInform Abstract: Antibody Catalysis of Difficult Chemical Transformations. Cheminform. 24: no-no. DOI: 10.1002/chin.199349319 |
0.493 |
|
| 2010 |
REYMOND J, JANDA KD, LERNER RA. ChemInform Abstract: Highly Enantioselective Protonation Catalyzed by an Antibody. Cheminform. 23: no-no. DOI: 10.1002/chin.199227073 |
0.357 |
|
| 2010 |
REYMOND J, JANDA KD, LERNER RA. ChemInform Abstract: Antibody Catalysis of Glycosidic Bond Hydrolysis. Cheminform. 23: no-no. DOI: 10.1002/chin.199210071 |
0.306 |
|
| 2010 |
JANDA KD, ASHLEY JA, JONES TM, MCLEOD DA, SCHLOEDER DM, WEINHOUSE MI, LERNER RA, GIBBS RA, BENKOVIC PA, HILHORST R, BENKOVIC SJ. ChemInform Abstract: Catalytic Antibodies with Acyl-Transfer Capabilities: Mechanistic and Kinetic Investigations. Cheminform. 22: no-no. DOI: 10.1002/chin.199115055 |
0.52 |
|
| 2009 |
Zhu X, Tanaka F, Lerner RA, Barbas CF, Wilson IA. Direct observation of an enamine intermediate in amine catalysis. Journal of the American Chemical Society. 131: 18206-7. PMID 19968282 DOI: 10.1021/Ja907271A |
0.607 |
|
| 2009 |
Grünewald J, Hunt GS, Dong L, Niessen F, Wen BG, Tsao ML, Perera R, Kang M, Laffitte BA, Azarian S, Ruf W, Nasoff M, Lerner RA, Schultz PG, Smider VV. Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America. 106: 4337-42. PMID 19246393 DOI: 10.1073/Pnas.0900507106 |
0.532 |
|
| 2009 |
Bowley DR, Jones TM, Burton DR, Lerner RA. Libraries against libraries for combinatorial selection of replicating antigen-antibody pairs. Proceedings of the National Academy of Sciences of the United States of America. 106: 1380-5. PMID 19139405 DOI: 10.1073/Pnas.0812291106 |
0.494 |
|
| 2008 |
Grünewald J, Tsao ML, Perera R, Dong L, Niessen F, Wen BG, Kubitz DM, Smider VV, Ruf W, Nasoff M, Lerner RA, Schultz PG. Immunochemical termination of self-tolerance. Proceedings of the National Academy of Sciences of the United States of America. 105: 11276-80. PMID 18685087 DOI: 10.1073/Pnas.0804157105 |
0.555 |
|
| 2008 |
Xu L, Yee H, Chan C, Kashyap AK, Horowitz L, Horowitz M, Bhatt RR, Lerner RA. Combinatorial surrobody libraries. Proceedings of the National Academy of Sciences of the United States of America. 105: 10756-61. PMID 18664586 DOI: 10.1073/Pnas.0805293105 |
0.452 |
|
| 2008 |
Tanaka F, Hu Y, Sutton J, Asawapornmongkol L, Fuller R, Olson AJ, Barbas CF, Lerner RA. Selection of phage-displayed peptides that bind to a particular ligand-bound antibody. Bioorganic & Medicinal Chemistry. 16: 5926-31. PMID 18472269 DOI: 10.1016/J.Bmc.2008.04.062 |
0.577 |
|
| 2008 |
Kashyap AK, Steel J, Oner AF, Dillon MA, Swale RE, Wall KM, Perry KJ, Faynboym A, Ilhan M, Horowitz M, Horowitz L, Palese P, Bhatt RR, Lerner RA. Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies. Proceedings of the National Academy of Sciences of the United States of America. 105: 5986-91. PMID 18413603 DOI: 10.1073/Pnas.0801367105 |
0.377 |
|
| 2008 |
Debler EW, Kaufmann GF, Meijler MM, Heine A, Mee JM, Pljevaljcic G, Di Bilio AJ, Schultz PG, Millar DP, Janda KD, Wilson IA, Gray HB, Lerner RA. Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex. Science (New York, N.Y.). 319: 1232-5. PMID 18309081 DOI: 10.1126/Science.1153445 |
0.495 |
|
| 2007 |
Dickerson TJ, McKenzie KM, Hoyt AS, Wood MR, Janda KD, Brenner SB, Lerner RA. Phage escape libraries for checkmate analysis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12703-8. PMID 17646645 DOI: 10.1073/Pnas.0705362104 |
0.382 |
|
| 2007 |
Abraham S, Guo F, Li LS, Rader C, Liu C, Barbas CF, Lerner RA, Sinha SC. Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 5584-9. PMID 17372220 DOI: 10.1073/Pnas.0700223104 |
0.561 |
|
| 2007 |
Tanaka F, Jones T, Kubitz D, Lerner RA. Anti-formyl peptide antibodies. Bioorganic & Medicinal Chemistry Letters. 17: 1943-5. PMID 17293112 DOI: 10.1016/J.Bmcl.2007.01.082 |
0.613 |
|
| 2006 |
Lerner RA. Manufacturing immunity to disease in a test tube: the magic bullet realized. Angewandte Chemie (International Ed. in English). 45: 8106-25. PMID 17120282 DOI: 10.1002/Anie.200603381 |
0.464 |
|
| 2006 |
Guo F, Das S, Mueller BM, Barbas CF, Lerner RA, Sinha SC. Breaking the one antibody-one target axiom. Proceedings of the National Academy of Sciences of the United States of America. 103: 11009-14. PMID 16822849 DOI: 10.1073/Pnas.0603822103 |
0.461 |
|
| 2006 |
Zhu X, Wentworth P, Kyle RA, Lerner RA, Wilson IA. Cofactor-containing antibodies: crystal structure of the original yellow antibody. Proceedings of the National Academy of Sciences of the United States of America. 103: 3581-5. PMID 16537445 DOI: 10.1073/Pnas.0600251103 |
0.486 |
|
| 2006 |
Nieva J, Kerwin L, Wentworth AD, Lerner RA, Wentworth P. Immunoglobulins can utilize riboflavin (Vitamin B2) to activate the antibody-catalyzed water oxidation pathway. Immunology Letters. 103: 33-8. PMID 16386801 DOI: 10.1016/J.Imlet.2005.11.020 |
0.384 |
|
| 2005 |
Matsushita H, Yamamoto N, Meijler MM, Wirsching P, Lerner RA, Matsushita M, Janda KD. Chiral sensing using a blue fluorescent antibody. Molecular Biosystems. 1: 303-6. PMID 16880995 DOI: 10.1039/B511408J |
0.363 |
|
| 2005 |
Matsushita M, Meijler MM, Wirsching P, Lerner RA, Janda KD. A blue fluorescent antibody-cofactor sensor for mercury. Organic Letters. 7: 4943-6. PMID 16235928 DOI: 10.1021/Ol051919W |
0.358 |
|
| 2005 |
Weinstain R, Lerner RA, Barbas CF, Shabat D. Antibody-catalyzed asymmetric intramolecular Michael addition of aldehydes and ketones to yield the disfavored cis-product. Journal of the American Chemical Society. 127: 13104-5. PMID 16173712 DOI: 10.1021/Ja0536825 |
0.646 |
|
| 2005 |
Amir RJ, Popkov M, Lerner RA, Barbas CF, Shabat D. Prodrug activation gated by a molecular "OR" logic trigger. Angewandte Chemie (International Ed. in English). 44: 4378-81. PMID 15942963 DOI: 10.1002/Anie.200500842 |
0.519 |
|
| 2005 |
Rajpal A, Beyaz N, Haber L, Cappuccilli G, Yee H, Bhatt RR, Takeuchi T, Lerner RA, Crea R. A general method for greatly improving the affinity of antibodies by using combinatorial libraries. Proceedings of the National Academy of Sciences of the United States of America. 102: 8466-71. PMID 15939870 DOI: 10.1073/Pnas.0503543102 |
0.393 |
|
| 2005 |
Kaufmann GF, Meijler MM, Sun C, Chen DW, Kujawa DP, Mee JM, Hoffman TZ, Wirsching P, Lerner RA, Janda KD. Enzymatic incorporation of an antibody-activated blue fluorophore into DNA. Angewandte Chemie (International Ed. in English). 44: 2144-8. PMID 15742317 DOI: 10.1002/Anie.200461143 |
0.392 |
|
| 2005 |
Haba K, Popkov M, Shamis M, Lerner RA, Barbas CF, Shabat D. Single-triggered trimeric prodrugs. Angewandte Chemie (International Ed. in English). 44: 716-20. PMID 15657968 DOI: 10.1002/Anie.200461657 |
0.526 |
|
| 2005 |
Debler EW, Kaufmann GF, Di Bilio A, Gray HB, Lerner RA, Janda KD, Wilson IA. Structural basis for blue and purple fluorescence of antibody-stilbene complexes Acta Crystallographica Section a Foundations of Crystallography. 61: c229-c230. DOI: 10.1107/S0108767305090227 |
0.369 |
|
| 2004 |
Felding-Habermann B, Lerner RA, Lillo A, Zhuang S, Weber MR, Arrues S, Gao C, Mao S, Saven A, Janda KD. Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America. 101: 17210-5. PMID 15563590 DOI: 10.1073/Pnas.0407869101 |
0.466 |
|
| 2004 |
Li LS, Rader C, Matsushita M, Das S, Barbas CF, Lerner RA, Sinha SC. Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices. Journal of Medicinal Chemistry. 47: 5630-40. PMID 15509162 DOI: 10.1021/Jm049666K |
0.565 |
|
| 2004 |
Zhu X, Tanaka F, Hu Y, Heine A, Fuller R, Zhong G, Olson AJ, Lerner RA, Barbas CF, Wilson IA. The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis. Journal of Molecular Biology. 343: 1269-80. PMID 15491612 DOI: 10.1016/J.Jmb.2004.08.102 |
0.716 |
|
| 2004 |
Sinha SC, Li LS, Watanabe S, Kaltgrad E, Tanaka F, Rader C, Lerner RA, Barbas CF. Aldolase antibody activation of prodrugs of potent aldehyde-containing cytotoxics for selective chemotherapy. Chemistry (Weinheim An Der Bergstrasse, Germany). 10: 5467-72. PMID 15378729 DOI: 10.1002/Chem.200400419 |
0.679 |
|
| 2004 |
Nyffeler PT, Boyle NA, Eltepu L, Wong CH, Eschenmoser A, Lerner RA, Wentworth P. Dihydrogen trioxide (HOOOH) is generated during the thermal reaction between hydrogen peroxide and ozone. Angewandte Chemie (International Ed. in English). 43: 4656-9. PMID 15317003 DOI: 10.1002/Anie.200460457 |
0.387 |
|
| 2004 |
Torres FE, Kuhn P, De Bruyker D, Bell AG, Wolkin MV, Peeters E, Williamson JR, Anderson GB, Schmitz GP, Recht MI, Schweizer S, Scott LG, Ho JH, Elrod SA, Schultz PG, ... Lerner RA, et al. Enthalpy arrays. Proceedings of the National Academy of Sciences of the United States of America. 101: 9517-22. PMID 15210951 DOI: 10.1073/Pnas.0403573101 |
0.429 |
|
| 2004 |
Tanaka F, Flores F, Kubitz D, Lerner RA, Barbas CF. Antibody-catalyzed aminolysis of a chloropyrimidine derivative. Chemical Communications (Cambridge, England). 1242-3. PMID 15136858 DOI: 10.1039/B403672G |
0.637 |
|
| 2004 |
Zhu X, Wentworth P, Wentworth AD, Eschenmoser A, Lerner RA, Wilson IA. Probing the antibody-catalyzed water-oxidation pathway at atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 101: 2247-52. PMID 14982995 DOI: 10.1073/Pnas.0307311101 |
0.421 |
|
| 2004 |
Sinha SC, Li LS, Miller GP, Dutta S, Rader C, Lerner RA. Prodrugs of dynemicin analogs for selective chemotherapy mediated by an aldolase catalytic Ab. Proceedings of the National Academy of Sciences of the United States of America. 101: 3095-9. PMID 14981258 DOI: 10.1073/Pnas.0307319101 |
0.56 |
|
| 2004 |
Tanaka F, Fuller R, Shim H, Lerner RA, Barbas CF. Evolution of aldolase antibodies in vitro: correlation of catalytic activity and reaction-based selection. Journal of Molecular Biology. 335: 1007-18. PMID 14698295 DOI: 10.1016/J.Jmb.2003.11.014 |
0.742 |
|
| 2003 |
Matsushita M, Yoshida K, Yamamoto N, Wirsching P, Lerner RA, Janda KD. High-throughput screening by using a blue-fluorescent antibody sensor. Angewandte Chemie (International Ed. in English). 42: 5984-7. PMID 14679549 DOI: 10.1002/Anie.200352793 |
0.322 |
|
| 2003 |
Rader C, Turner JM, Heine A, Shabat D, Sinha SC, Wilson IA, Lerner RA, Barbas CF. A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy. Journal of Molecular Biology. 332: 889-99. PMID 12972259 DOI: 10.1016/S0022-2836(03)00992-6 |
0.785 |
|
| 2003 |
Rader C, Sinha SC, Popkov M, Lerner RA, Barbas CF. Chemically programmed monoclonal antibodies for cancer therapy: adaptor immunotherapy based on a covalent antibody catalyst. Proceedings of the National Academy of Sciences of the United States of America. 100: 5396-400. PMID 12702756 DOI: 10.1073/Pnas.0931308100 |
0.595 |
|
| 2003 |
Lerner RA, Eschenmoser A. Ozone in biology. Proceedings of the National Academy of Sciences of the United States of America. 100: 3013-5. PMID 12631693 DOI: 10.1073/Pnas.0730791100 |
0.372 |
|
| 2003 |
Wentworth P, Wentworth AD, Zhu X, Wilson IA, Janda KD, Eschenmoser A, Lerner RA. Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens. Proceedings of the National Academy of Sciences of the United States of America. 100: 1490-3. PMID 12576548 DOI: 10.1073/Pnas.0437831100 |
0.408 |
|
| 2003 |
Mayfield SP, Franklin SE, Lerner RA. Expression and assembly of a fully active antibody in algae. Proceedings of the National Academy of Sciences of the United States of America. 100: 438-42. PMID 12522151 DOI: 10.1073/Pnas.0237108100 |
0.467 |
|
| 2002 |
Schultz PG, Yin J, Lerner RA. The chemistry of the antibody molecule. Angewandte Chemie (International Ed. in English). 41: 4427-37. PMID 12458503 DOI: 10.1002/1521-3773(20021202)41:23<4427::Aid-Anie4427>3.0.Co;2-K |
0.548 |
|
| 2002 |
Wentworth P, McDunn JE, Wentworth AD, Takeuchi C, Nieva J, Jones T, Bautista C, Ruedi JM, Gutierrez A, Janda KD, Babior BM, Eschenmoser A, Lerner RA. Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation. Science (New York, N.Y.). 298: 2195-9. PMID 12434011 DOI: 10.1126/Science.1077642 |
0.707 |
|
| 2002 |
Turner JM, Larsen NA, Basran A, Barbas CF, Bruce NC, Wilson IA, Lerner RA. Biochemical characterization and structural analysis of a highly proficient cocaine esterase. Biochemistry. 41: 12297-307. PMID 12369817 DOI: 10.1021/Bi026131P |
0.521 |
|
| 2002 |
Gao C, Mao S, Kaufmann G, Wirsching P, Lerner RA, Janda KD. A method for the generation of combinatorial antibody libraries using pIX phage display. Proceedings of the National Academy of Sciences of the United States of America. 99: 12612-6. PMID 12239343 DOI: 10.1073/Pnas.192467999 |
0.482 |
|
| 2002 |
Schultz PG, Lerner RA. Completing the circle. Nature. 418: 485. PMID 12152057 DOI: 10.1038/418485A |
0.563 |
|
| 2002 |
Larsen NA, Turner JM, Stevens J, Rosser SJ, Basran A, Lerner RA, Bruce NC, Wilson IA. Crystal structure of a bacterial cocaine esterase. Nature Structural Biology. 9: 17-21. PMID 11742345 DOI: 10.1038/Nsb742 |
0.508 |
|
| 2002 |
Schultz PG, Yin J, Lerner RA. Die Chemie von Antikörpern Angewandte Chemie. 114: 4607-4618. DOI: 10.1002/1521-3757(20021202)114:23<4607::Aid-Ange4607>3.0.Co;2-U |
0.383 |
|
| 2001 |
Sinha SC, Sun J, Wartmann M, Lerner RA. Synthesis of epothilone analogues by antibody-catalyzed resolution of thiazole aldol synthons on a multigram scale. Biological consequences of C-13 alkylation of epothilones. Chembiochem : a European Journal of Chemical Biology. 2: 656-65. PMID 11828502 DOI: 10.1002/1439-7633(20010903)2:9<656::Aid-Cbic656>3.0.Co;2-3 |
0.334 |
|
| 2001 |
Larsen NA, Heine A, Crane L, Cravatt BF, Lerner RA, Wilson IA. Structural basis for a disfavored elimination reaction in catalytic antibody 1D4. Journal of Molecular Biology. 314: 93-102. PMID 11724535 DOI: 10.1006/Jmbi.2001.5112 |
0.527 |
|
| 2001 |
Worrall DS, McDunn JE, List B, Reichart D, Hevener A, Gustafson T, Barbas CF, Lerner RA, Olefsky JM. Synthesis of an organoinsulin molecule that can be activated by antibody catalysis. Proceedings of the National Academy of Sciences of the United States of America. 98: 13514-8. PMID 11707596 DOI: 10.1073/Pnas.241516698 |
0.698 |
|
| 2001 |
Tanaka F, Kerwin L, Kubitz D, Lerner RA, Barbas CF. Visualizing antibody-catalyzed retro-aldol-retro-Michael reactions. Bioorganic & Medicinal Chemistry Letters. 11: 2983-6. PMID 11677141 DOI: 10.1016/S0960-894X(01)00605-9 |
0.619 |
|
| 2001 |
Subauste MC, List B, Guan X, Hahn KM, Lerner R, Gilula NB. A catalytic antibody produces fluorescent tracers of gap junction communication in living cells. The Journal of Biological Chemistry. 276: 49164-8. PMID 11606573 DOI: 10.1074/Jbc.M105700200 |
0.596 |
|
| 2001 |
Wentworth P, Jones LH, Wentworth AD, Zhu X, Larsen NA, Wilson IA, Xu X, Goddard WA, Janda KD, Eschenmoser A, Lerner RA. Antibody catalysis of the oxidation of water. Science (New York, N.Y.). 293: 1806-11. PMID 11546867 DOI: 10.1126/Science.1062722 |
0.376 |
|
| 2001 |
Jones LH, Harwig CW, Wentworth P, Simeonov A, Wentworth AD, Py S, Ashley JA, Lerner RA, Janda KD. Conversion of enediynes into quinones by antibody catalysis and in aqueous buffers: implications for an alternative enediyne therapeutic mechanism. Journal of the American Chemical Society. 123: 3607-8. PMID 11472138 DOI: 10.1021/Ja005864Z |
0.455 |
|
| 2001 |
Shabat D, Lode HN, Pertl U, Reisfeld RA, Rader C, Lerner RA, Barbas CF. In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy. Proceedings of the National Academy of Sciences of the United States of America. 98: 7528-33. PMID 11404472 DOI: 10.1073/Pnas.131187998 |
0.73 |
|
| 2001 |
Sinha SC, Sun J, Miller GP, Wartmann M, Lerner RA. Catalytic antibody route to the naturally occurring epothilones: total synthesis of epothilones A-F. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 1691-702. PMID 11349910 DOI: 10.1002/1521-3765(20010417)7:8<1691::Aid-Chem16910>3.0.Co;2-9 |
0.438 |
|
| 2000 |
Simeonov A, Matsushita M, Juban EA, Thompson EH, Hoffman TZ, Beuscher AE, Taylor MJ, Wirsching P, Rettig W, McCusker JK, Stevens RC, Millar DP, Schultz PG, Lerner RA, Janda KD. Blue-fluorescent antibodies. Science (New York, N.Y.). 290: 307-13. PMID 11030644 DOI: 10.1126/Science.290.5490.307 |
0.582 |
|
| 2000 |
Wentworth AD, Jones LH, Wentworth P, Janda KD, Lerner RA. Antibodies have the intrinsic capacity to destroy antigens. Proceedings of the National Academy of Sciences of the United States of America. 97: 10930-5. PMID 11005865 DOI: 10.1073/Pnas.97.20.10930 |
0.467 |
|
| 2000 |
Turner JM, Bui T, Lerner RA, Barbas CF, List B. An efficient benchtop system for multigram-scale kinetic resolutions using aldolase antibodies. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 2772-4. PMID 10985725 DOI: 10.1002/1521-3765(20000804)6:15<2772::Aid-Chem2772>3.0.Co;2-J |
0.719 |
|
| 2000 |
Hasserodt J, Janda KD, Lerner RA. A class of 4-aza-lithocholic acid-derived haptens for the generation of catalytic antibodies with steroid synthase capabilities. Bioorganic & Medicinal Chemistry. 8: 995-1003. PMID 10882011 DOI: 10.1016/S0968-0896(00)00036-5 |
0.372 |
|
| 2000 |
Karlstrom A, Zhong G, Rader C, Larsen NA, Heine A, Fuller R, List B, Tanaka F, Wilson IA, Barbas CF, Lerner RA. Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task. Proceedings of the National Academy of Sciences of the United States of America. 97: 3878-83. PMID 10760259 DOI: 10.1073/Pnas.97.8.3878 |
0.775 |
|
| 2000 |
Ly DH, Lockhart DJ, Lerner RA, Schultz PG. Mitotic misregulation and human aging. Science (New York, N.Y.). 287: 2486-92. PMID 10741968 DOI: 10.1126/Science.287.5462.2486 |
0.388 |
|
| 2000 |
List B, Lerner RA, Barbas CF. Proline-catalyzed direct asymmetric aldol reactions [13] Journal of the American Chemical Society. 122: 2395-2396. DOI: 10.1021/Ja994280Y |
0.571 |
|
| 2000 |
Hasserodt J, Janda KD, Lerner RA. Antibodies mimic natural oxidosqualene-cyclase action in steroid ring a formation Journal of the American Chemical Society. 122: 40-45. DOI: 10.1021/Ja993054L |
0.434 |
|
| 2000 |
Tanaka F, Lerner RA, Barbas CF. Reconstructing aldolase antibodies to alter their substrate specificity and turnover Journal of the American Chemical Society. 122: 4835-4836. DOI: 10.1021/Ja0005441 |
0.545 |
|
| 1999 |
Paschall CM, Hasserodt J, Jones T, Lerner RA, Janda KD, Christianson DW. Convergence of Catalytic Antibody and Terpene Cyclase Mechanisms: Polyene Cyclization Directed by Carbocation-π Interactions. Angewandte Chemie (International Ed. in English). 38: 1743-1747. PMID 29711206 DOI: 10.1002/(Sici)1521-3773(19990614)38:12<1743::Aid-Anie1743>3.0.Co;2-3 |
0.409 |
|
| 1999 |
Sinha SC, Sun J, Miller G, Barbas CF, Lerner RA. Sets of aldolase antibodies with antipodal reactivities. Formal synthesis of epothilone E by large-scale antibody-catalyzed resolution of thiazole aldol. Organic Letters. 1: 1623-6. PMID 10836025 DOI: 10.1021/Ol990261H |
0.371 |
|
| 1999 |
List B, Lerner RA, Barbas CF. Enantioselective aldol cyclodehydrations catalyzed by antibody 38C2. Organic Letters. 1: 59-61. PMID 10822533 DOI: 10.1021/Ol9905405 |
0.595 |
|
| 1999 |
Zhong G, Lerner RA, Barbas III. Broadening the Aldolase Catalytic Antibody Repertoire by Combining Reactive Immunization and Transition State Theory: New Enantio- and Diastereoselectivities. Angewandte Chemie (International Ed. in English). 38: 3738-3741. PMID 10649343 DOI: 10.1002/(Sici)1521-3773(19991216)38:24<3738::Aid-Anie3738>3.0.Co;2-2 |
0.632 |
|
| 1999 |
Lerner RA, Glassock RJ, Dixon FJ. The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis. Journal of the American Society of Nephrology : Jasn. 10: 1389-404. PMID 10361879 |
0.537 |
|
| 1999 |
Shabat D, Rader C, List B, Lerner RA, Barbas CF. Multiple event activation of a generic prodrug trigger by antibody catalysis. Proceedings of the National Academy of Sciences of the United States of America. 96: 6925-30. PMID 10359815 DOI: 10.1073/Pnas.96.12.6925 |
0.772 |
|
| 1999 |
Gruber K, Zhou B, Houk KN, Lerner RA, Shevlin CG, Wilson IA. Structural basis for antibody catalysis of a disfavored ring closure reaction. Biochemistry. 38: 7062-74. PMID 10353817 DOI: 10.1021/Bi990210S |
0.496 |
|
| 1999 |
Gao C, Mao S, Lo CH, Wirsching P, Lerner RA, Janda KD. Making artificial antibodies: a format for phage display of combinatorial heterodimeric arrays. Proceedings of the National Academy of Sciences of the United States of America. 96: 6025-30. PMID 10339535 DOI: 10.1073/Pnas.96.11.6025 |
0.413 |
|
| 1999 |
Taylor MJ, Yli-Kauhaluoma JT, Ashley JA, Wirsching P, Lerner RA, Janda KD. The α-ketoamide group: A new motif for the elicitation of catalytic antibodies for acyl-transfer reactions Journal of the Chemical Society - Perkin Transactions 1. 1133-1134. DOI: 10.1039/A902475A |
0.425 |
|
| 1999 |
Tanaka F, Lerner RA, Barbas CF. Thiazolium-dependent catalytic antibodies produced using a covalent modification strategy Chemical Communications. 1383-1384. DOI: 10.1039/A902337B |
0.66 |
|
| 1999 |
List B, Shabat D, Zhong G, Turner JM, Li A, Bui T, Anderson J, Lerner RA, Barbas CF. A catalytic enantioselective route to hydroxy-substituted quaternary carbon centers: Resolution of tertiary aldols with a catalytic antibody Journal of the American Chemical Society. 121: 7283-7291. DOI: 10.1021/Ja991507G |
0.814 |
|
| 1999 |
Tanaka F, Almer H, Lerner RA, Barbas CF. Catalytic single-chain antibodies possessing β-lactamase activity selected from a phage displayed combinatorial library using a mechanism-based inhibitor Tetrahedron Letters. 40: 8063-8066. DOI: 10.1016/S0040-4039(99)01695-0 |
0.599 |
|
| 1999 |
Shabat D, List B, Lerner RA, Barbas CF. A short enantioselective synthesis of 1-deoxy-L-xylulose by antibody catalysis Tetrahedron Letters. 40: 1437-1440. DOI: 10.1016/S0040-4039(98)02699-9 |
0.702 |
|
| 1999 |
Paschall CM, Hasserodt J, Jones T, Lerner RA, Janda KD, Christianson DW. Convergence of catalytic antibody and terpene cyclase mechanisms: Polyene cyclization directed by carbocation - π interactions Angewandte Chemie - International Edition. 38: 1743-1747. DOI: 10.1002/(SICI)1521-3773(19990614)38:12<1743::AID-ANIE1743>3.0.CO;2-3 |
0.307 |
|
| 1999 |
Zhong G, Lerner R, Barbas C. Erweiterung des Repertoires von katalytischen Antikörpern mit Aldolaseaktivität durch Kombination von reaktiver Immunisierung und Übergangszustandstheorie: neue Enantio- und Diastereoselektivitäten Angewandte Chemie. 111: 3957-3960. DOI: 10.1002/(Sici)1521-3757(19991216)111:24<3957::Aid-Ange3957>3.0.Co;2-H |
0.439 |
|
| 1998 |
Zhong G, Shabat D, List B, Anderson J, Sinha SC, Lerner RA, Barbas Iii CF. Catalytic Enantioselective Retro-Aldol Reactions: Kinetic Resolution of β-Hydroxyketones with Aldolase Antibodies. Angewandte Chemie (International Ed. in English). 37: 2481-2484. PMID 29711357 DOI: 10.1002/(Sici)1521-3773(19981002)37:18<2481::Aid-Anie2481>3.0.Co;2-T |
0.774 |
|
| 1998 |
List B, Barbas CF, Lerner RA. Aldol sensors for the rapid generation of tunable fluorescence by antibody catalysis. Proceedings of the National Academy of Sciences of the United States of America. 95: 15351-5. PMID 9860972 DOI: 10.1073/Pnas.95.26.15351 |
0.613 |
|
| 1998 |
Sinha SC, Barbas CF, Lerner RA. The antibody catalysis route to the total synthesis of epothilones. Proceedings of the National Academy of Sciences of the United States of America. 95: 14603-8. PMID 9843936 DOI: 10.1073/Pnas.95.25.14603 |
0.46 |
|
| 1998 |
Boger DL, Patterson JE, Guan X, Cravatt BF, Lerner RA, Gilula NB. Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide. Proceedings of the National Academy of Sciences of the United States of America. 95: 4810-5. PMID 9560184 DOI: 10.1073/Pnas.95.9.4810 |
0.543 |
|
| 1998 |
Taylor MJ, Hoffman TZ, Yli-Kauhaluoma JT, Lerner RA, Janda KD. A light-activated antibody catalyst Journal of the American Chemical Society. 120: 12783-12790. DOI: 10.1021/Ja982711R |
0.376 |
|
| 1998 |
Finn MG, Lerner RA, Barbas CF. Cofactor-Induced Refinement of Catalytic Antibody Activity: A Metal-Specific Allosteric Effect Journal of the American Chemical Society. 120: 2963-2964. DOI: 10.1021/Ja9737329 |
0.421 |
|
| 1998 |
Hoffmann T, Zhong G, List B, Shabat D, Anderson J, Gramatikova S, Lerner RA, Barbas CF. Aldolase antibodies of remarkable scope Journal of the American Chemical Society. 120: 2768-2779. DOI: 10.1021/Ja973676B |
0.765 |
|
| 1998 |
Zhong G, Shabat D, List B, Anderson J, Sinha SC, Lerner RA, Barbas CF. Catalytic enantioselective retro-aldol reactions: Kinetic resolution of β-hydroxyketones with aldolase antibodies Angewandte Chemie - International Edition. 37: 2481-2484. DOI: 10.1002/(SICI)1521-3773(19981002)37:18<2481::AID-ANIE2481>3.0.CO;2-T |
0.679 |
|
| 1998 |
List B, Shabat D, Barbas CF, Lerner RA. Enantioselective total synthesis of some brevicomins using aldolase antibody 38C2 Chemistry - a European Journal. 4: 881-885. DOI: 10.1002/(Sici)1521-3765(19980515)4:5<881::Aid-Chem881>3.0.Co;2-# |
0.727 |
|
| 1998 |
Zhong G, Shabat D, List B, Anderson J, Sinha SC, Lerner RA, Barbas CF. Katalytische enantioselektive Retro-Aldolreaktion: kinetische Racematspaltung von β-Hydroxyketonen durch Aldolase-Antikörper Angewandte Chemie. 110: 2609-2612. DOI: 10.1002/(Sici)1521-3757(19980918)110:18<2609::Aid-Ange2609>3.0.Co;2-E |
0.682 |
|
| 1997 |
Guan X, Cravatt BF, Ehring GR, Hall JE, Boger DL, Lerner RA, Gilula NB. The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells. The Journal of Cell Biology. 139: 1785-92. PMID 9412472 DOI: 10.1083/Jcb.139.7.1785 |
0.515 |
|
| 1997 |
Barbas CF, Heine A, Zhong G, Hoffmann T, Gramatikova S, Björnestedt R, List B, Anderson J, Stura EA, Wilson IA, Lerner RA. Immune versus natural selection: antibody aldolases with enzymic rates but broader scope. Science (New York, N.Y.). 278: 2085-92. PMID 9405338 DOI: 10.1126/Science.278.5346.2085 |
0.712 |
|
| 1997 |
Gao C, Lin CH, Lo CH, Mao S, Wirsching P, Lerner RA, Janda KD. Making chemistry selectable by linking it to infectivity. Proceedings of the National Academy of Sciences of the United States of America. 94: 11777-82. PMID 9342313 DOI: 10.1073/Pnas.94.22.11777 |
0.416 |
|
| 1997 |
Lin CH, Hoffman TZ, Wirsching P, Barbas CF, Janda KD, Lerner RA. On roads not taken in the evolution of protein catalysts: antibody steroid isomerases that use an enamine mechanism. Proceedings of the National Academy of Sciences of the United States of America. 94: 11773-6. PMID 9342312 DOI: 10.1073/Pnas.94.22.11773 |
0.432 |
|
| 1997 |
Janda KD, Lo LC, Lo CH, Sim MM, Wang R, Wong CH, Lerner RA. Chemical selection for catalysis in combinatorial antibody libraries. Science (New York, N.Y.). 275: 945-8. PMID 9020070 DOI: 10.1126/Science.275.5302.945 |
0.549 |
|
| 1997 |
Zhong G, Hoffmann T, Lerner RA, Danishefsky S, Barbas CF. Antibody-catalyzed enantioselective Robinson annulation Journal of the American Chemical Society. 119: 8131-8132. DOI: 10.1021/Ja970944X |
0.565 |
|
| 1997 |
Hasserodt J, Janda KD, Lerner RA. Formation of bridge-methylated decalins by antibody-catalyzed tandem cationic cyclization Journal of the American Chemical Society. 119: 5993-5998. DOI: 10.1021/Ja970675A |
0.427 |
|
| 1997 |
Li T, Lerner RA, Janda KD. Antibody-Catalyzed Cationic Reactions: Rerouting of Chemical Transformations via Antibody Catalysis Accounts of Chemical Research. 30: 115-121. DOI: 10.1021/Ar960172U |
0.476 |
|
| 1996 |
Cravatt BF, Giang DK, Mayfield SP, Boger DL, Lerner RA, Gilula NB. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature. 384: 83-7. PMID 8900284 DOI: 10.1038/384083A0 |
0.537 |
|
| 1996 |
Wagner J, Lerner RA, Barbas CF. Synthesis of five enantiomerically pure haptens designed for in vitro evolution of antibodies with peptidase activity Bioorganic and Medicinal Chemistry. 4: 901-916. PMID 8818241 DOI: 10.1016/0968-0896(96)00085-5 |
0.365 |
|
| 1996 |
Lerner RA, Barbas CF. Using the process of reactive immunization to induce catalytic antibodies with complex mechanisms: Aldolases Acta Chemica Scandinavica. 50: 672-678. PMID 8756355 DOI: 10.3891/Acta.Chem.Scand.50-0672 |
0.42 |
|
| 1996 |
Li T, Janda KD, Lerner RA. Cationic cyclopropanation by antibody catalysis Nature. 379: 326-327. PMID 8552185 DOI: 10.1038/379326a0 |
0.312 |
|
| 1996 |
Björnestedt R, Zhong G, Lerner RA, Barbas CF. Copying nature's mechanism for the decarboxylation of β-keto acids into catalytic antibodies by reactive immunization Journal of the American Chemical Society. 118: 11720-11724. DOI: 10.1021/Ja9620797 |
0.622 |
|
| 1996 |
Hasserodt J, Janda KD, Lerner RA. Antibody catalyzed terpenoid cyclization Journal of the American Chemical Society. 118: 11654-11655. DOI: 10.1021/Ja954316W |
0.499 |
|
| 1996 |
Patterson JE, Ollmann IR, Cravatt BF, Boger DL, Wong CH, Lerner RA. Inhibition of oleamide hydrolase catalyzed hydrolysis of the endogenous sleep-inducing lipid cis-9-octadecenamide Journal of the American Chemical Society. 118: 5938-5945. DOI: 10.1021/Ja954064Z |
0.607 |
|
| 1996 |
Bahr N, Güller R, Reymond JL, Lerner RA. A nitroxyl synthase catalytic antibody Journal of the American Chemical Society. 118: 3550-3555. DOI: 10.1021/Ja9538694 |
0.45 |
|
| 1996 |
Cravatt BF, Lerner RA, Boger DL. Structure determination of an endogenous sleep-inducing lipid, cis-9-octadecenamide (oleamide): A synthetic approach to the chemical analysis of trace quantities of a natural product Journal of the American Chemical Society. 118: 580-590. DOI: 10.1021/Ja9532345 |
0.511 |
|
| 1996 |
Lo CHL, Gao C, Mao S, Matsui K, Lerner RA, Janda KD. Chain shuffling: Investigations into the specificity and selectivity of antibody catalysis Israel Journal of Chemistry. 36: 195-198. DOI: 10.1002/Ijch.199600026 |
0.508 |
|
| 1996 |
Keinan E, Lerner RA. The first decade of antibody catalysis: Perspective and prospects Israel Journal of Chemistry. 36: 113-119. DOI: 10.1002/Ijch.199600017 |
0.657 |
|
| 1995 |
Wagner J, Lerner RA, Barbas CF. Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes Science. 270: 1797-1800. PMID 8525368 DOI: 10.1126/Science.270.5243.1797 |
0.458 |
|
| 1995 |
Fenniri H, Janda KD, Lerner RA. Encoded reaction cassette for the highly sensitive detection of the making and breaking of chemical bonds Proceedings of the National Academy of Sciences of the United States of America. 92: 2278-2282. PMID 7892261 DOI: 10.1073/Pnas.92.6.2278 |
0.324 |
|
| 1995 |
Cravatt BF, Prospero-Garcia O, Siuzdak G, Gilula NB, Henriksen SJ, Boger DL, Lerner RA. Chemical characterization of a family of brain lipids that induce sleep. Science (New York, N.Y.). 268: 1506-9. PMID 7770779 DOI: 10.1126/Science.7770779 |
0.522 |
|
| 1995 |
Light J, Lerner RA. Random mutagenesis of staphylococcal nuclease and phage display selection Bioorganic and Medicinal Chemistry. 3: 955-967. PMID 7582973 DOI: 10.1016/0968-0896(95)00075-R |
0.305 |
|
| 1995 |
Lerner RA, Janda KD. Catalytic antibodies: evolution of protein function in real time Exs. 73: 121-138. PMID 7579971 |
0.352 |
|
| 1995 |
Schultz PG, Lerner RA. From molecular diversity to catalysis: Lessons from the immune system Science. 269: 1835-1842. PMID 7569920 DOI: 10.1126/Science.7569920 |
0.547 |
|
| 1995 |
Koch T, Reymond JL, Lerner RA. Antibody catalysis of multistep reactions: An aldol addition followed by a disfavored elimination Journal of the American Chemical Society. 117: X-9387. DOI: 10.1021/Ja00142A001 |
0.455 |
|
| 1995 |
Janda KD, Shevlin CG, Lerner RA. Oxepane synthesis along a disfavored pathway: The rerouting of a chemical reaction using a catalytic antibody Journal of the American Chemical Society. 117: 2659-2660. DOI: 10.1021/Ja00114A035 |
0.439 |
|
| 1995 |
Li T, Janda KD, Hilton S, Lerner RA. An antibody-catalyzed nucleophilic substitution reaction at a primary carbon that appears to proceed by an ionization mechanism Journal of the American Chemical Society. 117: 2367-2368. DOI: 10.1021/Ja00113A033 |
0.397 |
|
| 1995 |
Rosenblum JS, Lo LC, Li T, Janda KD, Lerner RA. Antibody-catalyzed phosphate triester hydrolysis Angewandte Chemie (International Edition in English). 34: 2275-2277. DOI: 10.1002/Anie.199522751 |
0.486 |
|
| 1995 |
Koch T, Reymond JL, Lerner RA. Antibody catalysis of multistep reaction: An aldol addition followed by a disfavored elimination Journal of the American Chemical Society. 117: 9383-9387. |
0.348 |
|
| 1994 |
Li T, Janda KD, Ashley JA, Lerner RA. Antibody catalyzed cationic cyclization Science. 264: 1289-1293. PMID 8191282 DOI: 10.1126/Science.8191282 |
0.399 |
|
| 1994 |
Janda KD, Lo CHL, Li T, Barbas CF, Wirsching P, Lerner RA. Direct selection for a catalytic mechanism from combinatorial antibody libraries Proceedings of the National Academy of Sciences of the United States of America. 91: 2532-2536. PMID 8146149 DOI: 10.1073/Pnas.91.7.2532 |
0.45 |
|
| 1994 |
Lerner RA, Siuzdak G, Prospero-Garcia O, Henriksen SJ, Boger DL, Cravatt BF. Cerebrodiene: a brain lipid isolated from sleep-deprived cats. Proceedings of the National Academy of Sciences of the United States of America. 91: 9505-8. PMID 7937797 DOI: 10.1073/Pnas.91.20.9505 |
0.516 |
|
| 1994 |
Boger DL, Lerner RA, Cravatt BF. Synthesis of a Functionalized Rigid Bicyclo[2.2.1]heptane: A Useful Hapten for Eliciting Catalytic Antibodies The Journal of Organic Chemistry. 59: 5078-5079. DOI: 10.1021/Jo00096A064 |
0.658 |
|
| 1994 |
Cravatt BF, Ashley JA, Janda KD, Boger DL, Lerner RA. Crossing Extreme Mechanistic Barriers by Antibody Catalysis: Syn Elimination to a Cis Olefin Journal of the American Chemical Society. 116: 6013-6014. DOI: 10.1021/Ja00092A080 |
0.621 |
|
| 1994 |
Koch A, Reymond JL, Lerner RA. Antibody-Catalyzed Activation of Unfunctionalized Olefins for Highly Enantioselective Asymmetric Epoxidation Journal of the American Chemical Society. 116: 803-804. DOI: 10.1021/Ja00081A065 |
0.473 |
|
| 1994 |
Chen Y, Reymond JL, Lerner RA. An antibody-catalyzed 1,2-rearrangement of carbon - Carbon bonds Angewandte Chemie (International Edition in English). 33: 1607-1609. DOI: 10.1002/Anie.199416071 |
0.318 |
|
| 1994 |
Reymond JL, Reber JL, Lerner RA. Enantioselective, multigram-scale synthesis with a catalytic antibody Angewandte Chemie (International Edition in English). 33: 475-477. DOI: 10.1002/Anie.199404751 |
0.425 |
|
| 1994 |
Boger DL, Lerner RA, Cravatt BF. Synthesis of a functionalized rigid bicyclo[2.2.1]heptane: A useful hapten for eliciting catalytic antibodies Journal of Organic Chemistry. 59: 5078-5079. |
0.343 |
|
| 1993 |
Sarvetnick N, Gurushanthaiah D, Han N, Prudent J, Schultz P, Lerner R. Increasing the chemical potential of the germ-line antibody repertoire Proceedings of the National Academy of Sciences of the United States of America. 90: 4008-4011. PMID 8483917 DOI: 10.1073/Pnas.90.9.4008 |
0.543 |
|
| 1993 |
Janda KD, Shevlin CG, Lerner RA. Antibody catalysis of a disfavored chemical transformation Science. 259: 490-493. PMID 8424171 DOI: 10.1126/Science.8424171 |
0.439 |
|
| 1993 |
Barbas CF, Rosenblum JS, Lerner RA. Direct selection of antibodies that coordinate metals from semisynthetic combinatorial libraries Proceedings of the National Academy of Sciences of the United States of America. 90: 6385-6389. PMID 8341642 DOI: 10.1073/Pnas.90.14.6385 |
0.347 |
|
| 1993 |
Lerner RA. Catalytic antibodies: The concept and the promise Hospital Practice. 28: 53-59. PMID 8325916 DOI: 10.1080/21548331.1993.11442820 |
0.429 |
|
| 1993 |
Barbas CF, Amberg W, Simoncsits A, Jones TM, Lerner RA. Selection of human anti-hapten antibodies from semisynthetic libraries Gene. 137: 57-62. PMID 8282201 DOI: 10.1016/0378-1119(93)90251-W |
0.41 |
|
| 1993 |
Gouverneur VE, Houk KN, de Pascual-Teresa B, Beno B, Janda KD, Lerner RA. Control of the exo and endo pathways of the Diels-Alder reaction by antibody catalysis. Science (New York, N.Y.). 262: 204-8. PMID 8211138 DOI: 10.1126/Science.8211138 |
0.608 |
|
| 1993 |
Na J, Houk KN, Shevlin CG, Janda KD, Lerner RA. The energetic advantage of 5-exo versus 6-endo epoxide openings: a preference overwhelmed by antibody catalysis Journal of the American Chemical Society. 115: 8453-8454. DOI: 10.1021/Ja00071A067 |
0.472 |
|
| 1993 |
Wade WS, Ashley JA, Jahangiri GK, McElhaney G, Janda KD, Lerner RA. A highly specific metal-activated catalytic antibody Journal of the American Chemical Society. 115: 4906-4907. DOI: 10.1021/Ja00064A068 |
0.409 |
|
| 1993 |
Wade WS, Koh JS, Han N, Hoekstra DM, Lerner RA. Engineering metal coordination sites into the antibody light chain Journal of the American Chemical Society. 115: 4449-4456. DOI: 10.1021/Ja00064A005 |
0.332 |
|
| 1993 |
Reymond JL, Jahangiri GK, Stoudt C, Lerner RA. Antibody catalyzed hydrolysis of enol ethers Journal of the American Chemical Society. 115: 3909-3917. DOI: 10.1021/Ja00063A009 |
0.347 |
|
| 1993 |
Jack Chen YC, Danon T, Sastry L, Mubaraki M, Janda KD, Lerner RA. Catalytic antibodies from combinatorial libraries Journal of the American Chemical Society. 115: 357-358. DOI: 10.1021/Ja00054A058 |
0.767 |
|
| 1993 |
Schultz PG, Lerner RA. Antibody catalysis of difficult chemical transformations Accounts of Chemical Research. 26: 391-395. DOI: 10.1021/Ar00032A001 |
0.553 |
|
| 1993 |
Schultz PG, Lerner RA. Antibody catalysis of difficult chemical transformations Accounts of Chemical Research. 26: 391-395. |
0.305 |
|
| 1993 |
Na J, Houk KN, Shevlin CG, Janda KD, Lerner RA. The energetic advantage of 5-exo versus 6-endo epoxide openings: A preference overwhelmed by antibody catalysis Journal of the American Chemical Society. 115: 8453-8454. |
0.368 |
|
| 1992 |
Benkovic SJ, Adams J, Janda KD, Lerner RA. A catalytic antibody uses a multistep kinetic sequence. Ciba Foundation Symposium. 159: 4-9; discussion 9-12. PMID 1959451 DOI: 10.1002/9780470514108.ch2 |
0.439 |
|
| 1992 |
Barbas CF, Bain JD, Hoekstra DM, Lerner RA. Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem. Proceedings of the National Academy of Sciences of the United States of America. 89: 4457-61. PMID 1584777 DOI: 10.1073/Pnas.89.10.4457 |
0.494 |
|
| 1992 |
Gram H, Marconi LA, Barbas CF, Collet TA, Lerner RA, Kang AS. In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library Proceedings of the National Academy of Sciences of the United States of America. 89: 3576-3580. PMID 1565653 DOI: 10.1073/Pnas.89.8.3576 |
0.469 |
|
| 1992 |
Lerner RA, Kang AS, Bain JD, Burton DR, Barbas CF. Antibodies without immunization. Science (New York, N.Y.). 258: 1313-4. PMID 1455226 DOI: 10.1126/Science.1455226 |
0.424 |
|
| 1992 |
Collet TA, Roben P, O'Kennedy R, Barbas CF, Burton DR, Lerner RA. A binary plasmid system for shuffling combinatorial antibody libraries Proceedings of the National Academy of Sciences of the United States of America. 89: 10026-10030. PMID 1438192 DOI: 10.1073/Pnas.89.21.10026 |
0.387 |
|
| 1992 |
Huse WD, Sastry L, Iverson SA, Kang AS, Alting-Mees M, Burton DR, Benkovic SJ, Lerner RA. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. 1989. Biotechnology (Reading, Mass.). 24: 517-23. PMID 1422064 |
0.679 |
|
| 1992 |
Tsang P, Rance M, Fieser TM, Ostresh JM, Houghten RA, Lerner RA, Wright PE. Conformation and dynamics of an Fab′-bound peptide by isotope-edited NMR spectroscopy Biochemistry. 31: 3862-3871. PMID 1373648 DOI: 10.1021/Bi00130A018 |
0.33 |
|
| 1992 |
Alexander H, Alexander S, Getzoff ED, Tainer JA, Geysen HM, Lerner RA. Altering the antigenicity of proteins Proceedings of the National Academy of Sciences of the United States of America. 89: 3352-3356. PMID 1373498 DOI: 10.1073/Pnas.89.8.3352 |
0.419 |
|
| 1992 |
Zebedee SL, Barbas CF, Hom YL, Caothien RH, Graff R, DeGraw J, Pyati J, LaPolla R, Burton DR, Lerner RA, Thornton GB. Human combinatorial antibody libraries to hepatitis B surface antigen Proceedings of the National Academy of Sciences of the United States of America. 89: 3175-3179. PMID 1373487 DOI: 10.1073/Pnas.89.8.3175 |
0.419 |
|
| 1992 |
Fernholz E, Schloeder D, Liu KKC, Bradshaw CW, Huang H, Janda K, Lerner RA, Wong CH. Specificity of antibody-catalyzed transesterifications using enol esters: A comparison with lipase reactions Journal of Organic Chemistry. 57: 4756-4761. DOI: 10.1021/Jo00043A042 |
0.462 |
|
| 1992 |
Gibbs RA, Benkovic PA, Janda KD, Lerner RA, Benkovic SJ. Substituent effects of an antibody-catalyzed hydrolysis of phenyl esters: further evidence for an acyl-antibody intermediate Journal of the American Chemical Society. 114: 3528-3534. DOI: 10.1021/Ja00035A057 |
0.57 |
|
| 1992 |
Reymond JL, Janda KD, Lerner RA. Highly enantioselective protonation catalyzed by an antibody Journal of the American Chemical Society. 114: 2257-2258. DOI: 10.1021/Ja00032A050 |
0.474 |
|
| 1992 |
Light J, Lerner RA. Phophabs: Antibody-phage-alkaline phosphatase conjugates for one step ELISA's without immunization Bioorganic and Medicinal Chemistry Letters. 2: 1073-1078. DOI: 10.1016/S0960-894X(00)80621-6 |
0.473 |
|
| 1992 |
Gibbs RA, Benkovic PA, Janda KD, Lerner RA, Benkovic SJ. Substituent effects on an antibody-catalyzed hydrolysis of phenyl esters: Further evidence for an acyl-antibody intermediate Journal of the American Chemical Society. 114: 3528-3534. |
0.386 |
|
| 1991 |
Wirsching P, Ashley JA, Benkovic SJ, Janda KD, Lerner RA. An unexpectedly efficient catalytic antibody operating by ping-pong and induced fit mechanisms. Science (New York, N.Y.). 252: 680-5. PMID 2024120 DOI: 10.1126/Science.2024120 |
0.613 |
|
| 1991 |
Lerner RA, Benkovic SJ, Schultz PG. At the crossroads of chemistry and immunology: catalytic antibodies. Science (New York, N.Y.). 252: 659-67. PMID 2024118 DOI: 10.1126/Science.2024118 |
0.684 |
|
| 1991 |
Iverson BL, Iverson SA, Cameron KE, Jahangiri GK, Pasternak DS, Lerner RA. Tritylase antibodies. Ciba Foundation Symposium. 159: 227-33; discussion 2. PMID 1959450 |
0.646 |
|
| 1991 |
Lerner RA, Barbas CF, Kang AS, Burton DR. On the use of combinatorial antibody libraries to clone the "fossil record" of an individual's immune response. Proceedings of the National Academy of Sciences of the United States of America. 88: 9705-6. PMID 1946391 DOI: 10.1073/Pnas.88.21.9705 |
0.371 |
|
| 1991 |
Kang AS, Barbas CF, Janda KD, Benkovic SJ, Lerner RA. Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces. Proceedings of the National Academy of Sciences of the United States of America. 88: 4363-6. PMID 1903540 DOI: 10.1073/Pnas.88.10.4363 |
0.599 |
|
| 1991 |
Barbas CF, Kang AS, Lerner RA, Benkovic SJ. Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proceedings of the National Academy of Sciences of the United States of America. 88: 7978-82. PMID 1896445 DOI: 10.1073/Pnas.88.18.7978 |
0.556 |
|
| 1991 |
Sastry L, Mubaraki M, Janda KD, Benkovic SJ, Lerner RA. Screening combinatorial antibody libraries for catalytic acyl transfer reactions. Ciba Foundation Symposium. 159: 145-51; discussion 1. PMID 1835693 DOI: 10.1002/9780470514108.ch10 |
0.778 |
|
| 1991 |
Burton DR, Barbas CF, Persson MA, Koenig S, Chanock RM, Lerner RA. A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals. Proceedings of the National Academy of Sciences of the United States of America. 88: 10134-7. PMID 1719545 DOI: 10.1073/Pnas.88.22.10134 |
0.442 |
|
| 1991 |
Alexander H, Alexander S, Heffron F, Fieser TM, Hay BN, Getzoff ED, Tainer JA, Lerner RA. Synthesis and characterization of a recombinant myohemerythrin protein encoded by a synthetic gene Gene. 99: 151-156. PMID 1708739 DOI: 10.1016/0378-1119(91)90121-Q |
0.397 |
|
| 1991 |
Fujii I, Lerner RA, Janda KD. Enantiofacial protonation by catalytic antibodies Journal of the American Chemical Society. 113: 8528-8529. DOI: 10.1021/Ja00022A054 |
0.467 |
|
| 1991 |
Ikeda S, Weinhouse MI, Janda KD, Lerner RA, Danishefsky SJ. Asymmetric induction via a catalytic antibody Journal of the American Chemical Society. 113: 7763-7764. DOI: 10.1021/Ja00020A049 |
0.494 |
|
| 1991 |
Janda KD, Ashley JA, Jones TM, McLeod DA, Schloeder DM, Weinhouse MI, Lerner RA, Gibbs RA, Benkovic PA. Catalytic antibodies with acyl-transfer capabilities: mechanistic and kinetic investigations Journal of the American Chemical Society. 113: 291-297. DOI: 10.1021/Ja00001A042 |
0.443 |
|
| 1991 |
Barbas CF, Lerner RA. Combinatorial immunoglobulin libraries on the surface of phage (Phabs): Rapid selection of antigen-specific fabs Methods. 2: 119-124. DOI: 10.1016/S1046-2023(05)80212-9 |
0.424 |
|
| 1991 |
Kang AS, Burton DR, Lerner RA. Combinatorial immunoglobulin libraries in phage λ Methods. 2: 111-118. DOI: 10.1016/S1046-2023(05)80211-7 |
0.406 |
|
| 1991 |
Janda KD, Benkovic SJ, McLeod DA, Schloeder DM, Lerner RA. Substrate attenuation: An approach to improve antibody catalysis Tetrahedron. 47: 2503-2506. DOI: 10.1016/S0040-4020(01)81784-1 |
0.595 |
|
| 1991 |
Reymond J, Janda KD, Lerner RA. Antibody Catalysis of Glycosidic Bond Hydrolysis Angewandte Chemie International Edition in English. 30: 1711-1713. DOI: 10.1002/Anie.199117111 |
0.42 |
|
| 1990 |
Norrby E, Biberfeld G, Johnson PR, Parks DE, Houghten RA, Lerner RA. The chemistry of site-directed serology for HIV infections. Aids Research and Human Retroviruses. 5: 487-93. PMID 2480152 DOI: 10.1089/Aid.1989.5.487 |
0.366 |
|
| 1990 |
Roberts VA, Iverson BL, Iverson SA, Benkovic SJ, Lerner RA, Getzoff ED, Tainer JA. Antibody remodeling: a general solution to the design of a metal-coordination site in an antibody binding pocket. Proceedings of the National Academy of Sciences of the United States of America. 87: 6654-8. PMID 2395868 DOI: 10.1073/Pnas.87.17.6654 |
0.691 |
|
| 1990 |
Stanfield RL, Fieser TM, Lerner RA, Wilson IA. Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A. Science (New York, N.Y.). 248: 712-9. PMID 2333521 DOI: 10.1126/Science.2333521 |
0.368 |
|
| 1990 |
Persson MA, Lerner RA. Increased yield of antibody-producing murine spleen cell hybridomas from fusions cultured in medium supplemented with mouse serum. Journal of Immunological Methods. 127: 39-42. PMID 2319141 DOI: 10.1016/0022-1759(90)90338-V |
0.376 |
|
| 1990 |
Benkovic SJ, Adams JA, Borders CL, Janda KD, Lerner RA. The enzymic nature of antibody catalysis: development of multistep kinetic processing. Science (New York, N.Y.). 250: 1135-9. PMID 2251500 DOI: 10.1126/Science.2251500 |
0.61 |
|
| 1990 |
Iverson BL, Iverson SA, Roberts VA, Getzoff ED, Tainer JA, Benkovic SJ, Lerner RA. Metalloantibodies. Science (New York, N.Y.). 249: 659-62. PMID 2116666 |
0.537 |
|
| 1990 |
Wright PE, Dyson HJ, Lerner RA, Riechmann L, Tsang P. Antigen-antibody interactions: an NMR approach. Biochemical Pharmacology. 40: 83-8. PMID 1695509 DOI: 10.1016/0006-2952(90)90182-K |
0.408 |
|
| 1990 |
Akerlind-Stopner B, Utter G, Mufson MA, Orvell C, Lerner RA, Norrby E. A subgroup-specific antigenic site in the G protein of respiratory syncytial virus forms a disulfide-bonded loop. Journal of Virology. 64: 5143-5148. DOI: 10.1128/Jvi.64.10.5143-5148.1990 |
0.411 |
|
| 1990 |
Janda KD, Weinhouse MI, Schloeder DM, Lerner RA, Benkovic SJ. Bait and switch strategy for obtaining catalytic antibodies with acyl-transfer capabilities Journal of the American Chemical Society. 112: 1274-1275. DOI: 10.1021/Ja00159A074 |
0.556 |
|
| 1989 |
Lerner RA, Benkovic SJ. Principles of antibody catalysis. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 9: 107-12. PMID 3067727 DOI: 10.1002/Bies.950090402 |
0.61 |
|
| 1989 |
Iverson BL, Lerner RA. Sequence-specific peptide cleavage catalyzed by an antibody. Science (New York, N.Y.). 243: 1184-8. PMID 2922606 DOI: 10.1126/Science.2922606 |
0.638 |
|
| 1989 |
Janda KD, Benkovic SJ, Lerner RA. Catalytic antibodies with lipase activity and R or S substrate selectivity. Science (New York, N.Y.). 244: 437-40. PMID 2717936 DOI: 10.1126/Science.2717936 |
0.549 |
|
| 1989 |
Iverson SA, Sastry L, Huse WD, Sorge JA, Benkovic SJ, Lerner RA. A combinatorial system for cloning and expressing the catalytic antibody repertoire in Escherichia coli. Cold Spring Harbor Symposia On Quantitative Biology. 54: 273-81. PMID 2700937 DOI: 10.1101/Sqb.1989.054.01.034 |
0.771 |
|
| 1989 |
Huse WD, Sastry L, Iverson SA, Kang AS, Alting-Mees M, Burton DR, Benkovic SJ, Lerner RA. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science (New York, N.Y.). 246: 1275-81. PMID 2531466 DOI: 10.1126/Science.2531466 |
0.78 |
|
| 1989 |
Sastry L, Alting-Mees M, Huse WD, Short JM, Sorge JA, Hay BN, Janda KD, Benkovic SJ, Lerner RA. Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: construction of a heavy chain variable region-specific cDNA library. Proceedings of the National Academy of Sciences of the United States of America. 86: 5728-32. PMID 2503822 DOI: 10.1073/Pnas.86.15.5728 |
0.789 |
|
| 1989 |
Szigeti R, Kallin B, Dillner J, Henle G, Henle W, Lerner RA, Rymo L, Timar L, Klein G. Epstein-Barr virus (EBV) antigen-specific leukocyte migration inhibition in infectious mononucleosis. II. Kinetics of sensitization against five EBV-encoded nuclear proteins and the latent membrane protein. Clinical Immunology and Immunopathology. 51: 396-405. PMID 2470542 DOI: 10.1016/0090-1229(89)90037-8 |
0.337 |
|
| 1989 |
Schwabacher AW, Weinhouse MI, Auditor MTM, Lerner RA. Metalloselective anti-porphyrin monoclonal antibodies Journal of the American Chemical Society. 111: 2344-2346. DOI: 10.1021/Ja00188A082 |
0.46 |
|
| 1988 |
Tramontano A, Janda K, Napper AD, Benkovic SJ, Lerner RA. Catalytic antibodies. Cold Spring Harbor Symposia On Quantitative Biology. 52: 91-6. PMID 3454298 DOI: 10.1101/sqb.1987.052.01.013 |
0.395 |
|
| 1988 |
Janda KD, Schloeder D, Benkovic SJ, Lerner RA. Induction of an antibody that catalyzes the hydrolysis of an amide bond. Science (New York, N.Y.). 241: 1188-91. PMID 3413482 DOI: 10.1126/Science.3413482 |
0.582 |
|
| 1988 |
Benkovic SJ, Napper AD, Lerner RA. Catalysis of a stereospecific bimolecular amide synthesis by an antibody. Proceedings of the National Academy of Sciences of the United States of America. 85: 5355-8. PMID 3399496 DOI: 10.1073/Pnas.85.15.5355 |
0.575 |
|
| 1988 |
Johnson PR, Parks DE, Norrby E, Lerner RA, Purcell RH, Chanock RM. Site-directed ELISA identifies a highly antigenic region of the simian immunodeficiency virus transmembrane glycoprotein. Aids Research and Human Retroviruses. 4: 159-64. PMID 3395516 DOI: 10.1089/Aid.1988.4.159 |
0.396 |
|
| 1988 |
Getzoff ED, Tainer JA, Lerner RA, Geysen HM. The chemistry and mechanism of antibody binding to protein antigens Advances in Immunology. 43: 1-98. PMID 3055852 DOI: 10.1016/S0065-2776(08)60363-6 |
0.445 |
|
| 1988 |
Hatzubai A, Lerner RA, Klein G, Sulitzeanu D. Proteins in normal and malignant cells, cross-reacting with the latent membrane protein encoded by Epstein-Barr virus. European Journal of Immunology. 18: 1283-8. PMID 2843380 DOI: 10.1002/Eji.1830180820 |
0.389 |
|
| 1988 |
Ricksten A, Kallin B, Alexander H, Dillner J, Fåhraeus R, Klein G, Lerner R, Rymo L. BamHI E region of the Epstein-Barr virus genome encodes three transformation-associated nuclear proteins. Proceedings of the National Academy of Sciences of the United States of America. 85: 995-9. PMID 2829223 DOI: 10.1073/Pnas.85.4.995 |
0.376 |
|
| 1988 |
Field J, Nikawa J, Broek D, MacDonald B, Rodgers L, Wilson IA, Lerner RA, Wigler M. Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Molecular and Cellular Biology. 8: 2159-65. PMID 2455217 DOI: 10.1128/mcb.8.5.2159-2165.1988 |
0.343 |
|
| 1988 |
Tramontano A, Ammann AA, Lerner RA. Antibody catalysis approaching the activity of enzymes Journal of the American Chemical Society. 110: 2282-2286. DOI: 10.1021/Ja00215A045 |
0.404 |
|
| 1988 |
JANDA KD, LERNER RA, TRAMONTANO A. ChemInform Abstract: Antibody Catalysis of Bimolecular Amide Formation. Cheminform. 19. DOI: 10.1002/chin.198845122 |
0.374 |
|
| 1987 |
Getzoff ED, Geysen HM, Rodda SJ, Alexander H, Tainer JA, Lerner RA. Mechanisms of antibody binding to a protein Science. 235: 1191-1196. PMID 3823879 DOI: 10.1126/Science.3823879 |
0.389 |
|
| 1987 |
Geysen HM, Tainer JA, Rodda SJ, Mason TJ, Alexander H, Getzoff ED, Lerner RA. Chemistry of antibody binding to a protein Science. 235: 1184-1190. PMID 3823878 DOI: 10.1126/Science.3823878 |
0.432 |
|
| 1987 |
Lai EH, Kabat EA, Meienhofer J, Heimer EP, Olson AJ, Lerner R. Inhibition of phosphorylcholine binding to antibodies using synthetic peptides. Nature. 325: 168-71. PMID 3808074 DOI: 10.1038/325168A0 |
0.342 |
|
| 1987 |
Napper AD, Benkovic SJ, Tramontano A, Lerner RA. A stereospecific cyclization catalyzed by an antibody. Science (New York, N.Y.). 237: 1041-3. PMID 3616626 DOI: 10.1126/Science.3616626 |
0.621 |
|
| 1987 |
Norrby E, Mufson MA, Alexander H, Houghten RA, Lerner RA. Site-directed serology with synthetic peptides representing the large glycoprotein G of respiratory syncytial virus. Proceedings of the National Academy of Sciences of the United States of America. 84: 6572-6. PMID 3476962 DOI: 10.1073/Pnas.84.18.6572 |
0.392 |
|
| 1987 |
Norrby E, Biberfeld G, Chiodi F, Gegerfeldt Av, Nauclér A, Parks E, Lerner R. Discrimination between antibodies to HIV and to related retroviruses using site-directed serology. Nature. 329: 248-250. PMID 3041232 DOI: 10.1038/329248A0 |
0.337 |
|
| 1987 |
Fieser TM, Tainer JA, Geysen HM, Houghten RA, Lerner RA. Influence of protein flexibility and peptide conformation on reactivity of monoclonal anti-peptide antibodies with a protein alpha-helix. Proceedings of the National Academy of Sciences of the United States of America. 84: 8568-72. PMID 2446325 DOI: 10.1073/Pnas.84.23.8568 |
0.457 |
|
| 1987 |
Dillner J, Szigeti R, Henle W, Henle G, Lerner RA, Klein G. Cellular and humoral immune responses to synthetic peptides deduced from the amino-acid sequences of Epstein-Barr virus-encoded proteins in EBV-transformed cells. International Journal of Cancer. Journal International Du Cancer. 40: 455-60. PMID 2444542 DOI: 10.1002/Ijc.2910400404 |
0.444 |
|
| 1987 |
GEYSEN HM, RODDA SJ, MASON TJ, TAINER JA, ALEXANDER H, GETZOFF ED, LERNER RA. Response: Antigenicity of Myohemerythrin Science. 238: 1584-1586. DOI: 10.1126/Science.238.4833.1584-A |
0.314 |
|
| 1987 |
Lerner RA, Tramontano A. Antibodies as enzymes Trends in Biochemical Sciences. 12: 427-430. DOI: 10.1016/0968-0004(87)90208-8 |
0.447 |
|
| 1986 |
Niman HL, Thompson AM, Yu A, Markman M, Willems JJ, Herwig KR, Habib NA, Wood CB, Houghten RA, Lerner RA. Anti-peptide antibodies detect oncogene-related proteins in urine. Proceedings of the National Academy of Sciences of the United States of America. 82: 7924-8. PMID 3906653 DOI: 10.1073/Pnas.82.23.7924 |
0.35 |
|
| 1986 |
Tramontano A, Janda KD, Lerner RA. Chemical reactivity at an antibody binding site elicited by mechanistic design of a synthetic antigen. Proceedings of the National Academy of Sciences of the United States of America. 83: 6736-40. PMID 3462723 DOI: 10.1073/Pnas.83.18.6736 |
0.454 |
|
| 1986 |
Dillner J, Kallin B, Alexander H, Ernberg I, Uno M, Ono Y, Klein G, Lerner RA. An Epstein-Barr virus (EBV)-determined nuclear antigen (EBNA5) partly encoded by the transformation-associated Bam WYH region of EBV DNA: preferential expression in lymphoblastoid cell lines. Proceedings of the National Academy of Sciences of the United States of America. 83: 6641-5. PMID 3018741 DOI: 10.1073/Pnas.83.17.6641 |
0.344 |
|
| 1986 |
Sternås L, Eliasson L, Lerner R, Klein G. Quantitation of Epstein-Barr virus (EBV)-determined nuclear antigen (EBNA) by a two-site enzyme immunoassay, in parallel with EBV-DNA Journal of Immunological Methods. 89: 151-158. PMID 3009623 DOI: 10.1016/0022-1759(86)90352-2 |
0.336 |
|
| 1986 |
Ackermann M, Chou J, Sarmiento M, Lerner RA, Roizman B. Identification by antibody to a synthetic peptide of a protein specified by a diploid gene located in the terminal repeats of the L component of herpes simplex virus genome. Journal of Virology. 58: 843-850. DOI: 10.1128/Jvi.58.3.843-850.1986 |
0.333 |
|
| 1985 |
Dyson HJ, Cross KJ, Houghten RA, Wilson IA, Wright PE, Lerner RA. The immunodominant site of a synthetic immunogen has a conformational preference in water for a type-II reverse turn. Nature. 318: 480-3. PMID 4069219 DOI: 10.1038/318480a0 |
0.319 |
|
| 1985 |
Francis MJ, Fry CM, Rowlands DJ, Brown F, Bittle JL, Houghten RA, Lerner RA. Immunological priming with synthetic peptides of foot-and-mouth disease virus. The Journal of General Virology. 2347-54. PMID 2997370 DOI: 10.1099/0022-1317-66-11-2347 |
0.366 |
|
| 1985 |
Moriarty AM, Alexander H, Lerner RA, Thornton GB. Antibodies to peptides detect new hepatitis B antigen: serological correlation with hepatocellular carcinoma. Science (New York, N.Y.). 227: 429-33. PMID 2981434 DOI: 10.1126/Science.2981434 |
0.353 |
|
| 1985 |
Tainer JA, Getzoff ED, Paterson Y, Olson AJ, Lerner RA. The atomic mobility component of protein antigenicity Annual Review of Immunology. 3: 501-535. PMID 2415142 DOI: 10.1146/Annurev.Iy.03.040185.002441 |
0.453 |
|
| 1985 |
Wilson IA, Haft DH, Getzoff ED, Tainer JA, Lerner RA, Brenner S. Identical short peptide sequences in unrelated proteins can have different conformations: A testing ground for theories of immune recognition Proceedings of the National Academy of Sciences of the United States of America. 82: 5255-5259. PMID 2410917 DOI: 10.1073/Pnas.82.16.5255 |
0.358 |
|
| 1985 |
Dillner J, Kallin B, Klein G, Jörnvall H, Alexander H, Lerner R. Antibodies against synthetic peptides react with the second Epstein-Barr virus-associated nuclear antigen. The Embo Journal. 4: 1813-1818. DOI: 10.1002/J.1460-2075.1985.Tb03855.X |
0.384 |
|
| 1984 |
Lamb JR, Zanders ED, Lake P, Webster RG, Eckels DD, Woody JN, Green N, Lerner RA, Feldmann M. Inhibition of T cell proliferation by antibodies to synthetic peptides. European Journal of Immunology. 14: 153-7. PMID 6607839 DOI: 10.1002/Eji.1830140209 |
0.405 |
|
| 1984 |
Milner RJ, Bloom FE, Lai C, Lerner RA, Sutcliffe JG. Brain-specific genes have identifier sequences in their introns. Proceedings of the National Academy of Sciences of the United States of America. 81: 713-7. PMID 6583673 DOI: 10.1073/Pnas.81.3.713 |
0.479 |
|
| 1984 |
Shinnick TM, Sutcliffe JG, Green N, Lerner RA. Peptide-elicited protein-reactive antibodies in molecular biology and medicine. The Journal of Investigative Dermatology. 83: 112s-115s. PMID 6376645 DOI: 10.1038/Jid.1984.31 |
0.594 |
|
| 1984 |
Macfarlan RI, Dietzschold B, Wiktor TJ, Kiel M, Houghten R, Lerner RA, Sutcliffe JG, Koprowski H. T cell responses to cleaved rabies virus glycoprotein and to synthetic peptides. Journal of Immunology (Baltimore, Md. : 1950). 133: 2748-52. PMID 6332859 |
0.462 |
|
| 1984 |
Tainer JA, Getzoff ED, Alexander H, Houghten RA, Olson AJ, Lerner RA, Hendrickson WA. The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein Nature. 312: 127-134. PMID 6209578 DOI: 10.1038/312127A0 |
0.429 |
|
| 1984 |
Dillner J, Sternås L, Kallin B, Alexander H, Ehlin-Henriksson B, Jörnvall H, Klein G, Lerner R. Antibodies against a synthetic peptide identify the Epstein-Barr virus-determined nuclear antigen. Proceedings of the National Academy of Sciences of the United States of America. 81: 4652-6. PMID 6205400 DOI: 10.1073/Pnas.81.15.4652 |
0.441 |
|
| 1984 |
Wilson IA, Niman HL, Houghten RA, Cherenson AR, Connolly ML, Lerner RA. The structure of an antigenic determinant in a protein. Cell. 37: 767-78. PMID 6204768 DOI: 10.1016/0092-8674(84)90412-4 |
0.425 |
|
| 1984 |
Seiden MV, Clevinger B, McMillan S, Srouji A, Lerner R, Davie JM. Chemical synthesis of idiotopes. Evidence that antisera to the same JH1 peptide detect multiple binding site-associated idiotopes. The Journal of Experimental Medicine. 159: 1338-50. PMID 6201582 DOI: 10.1084/Jem.159.5.1338 |
0.358 |
|
| 1984 |
Seiden MV, Clevinger B, Srouji T, Davie JM, McMillan S, Lerner R. A synthetic peptide induces a new anti-dextran idiotype. Annales D'Immunologie. 135: 77-82. PMID 6201130 DOI: 10.1016/S0769-2625(84)80015-X |
0.315 |
|
| 1984 |
Chen PP, Houghten RA, Fong S, Rhodes GH, Gilbertson TA, Vaughan JH, Lerner RA, Carson DA. Anti-hypervariable region antibody induced by a defined peptide: an approach for studying the structural correlates of idiotypes. Proceedings of the National Academy of Sciences of the United States of America. 81: 1784-8. PMID 6200884 DOI: 10.1073/Pnas.81.6.1784 |
0.477 |
|
| 1984 |
Niman HL, Hough-Evans BR, Vacquier VD, Britten RJ, Lerner RA, Davidson EH. Proteins of the sea urchin egg vitelline layer. Developmental Biology. 102: 390-401. PMID 6200373 DOI: 10.1016/0012-1606(84)90203-3 |
0.406 |
|
| 1984 |
Sutcliffe JG, Milner RJ, Gottesfeld JM, Lerner RA. Identifier sequences are transcribed specifically in brain. Nature. 308: 237-41. PMID 6199680 DOI: 10.1038/308237A0 |
0.475 |
|
| 1984 |
Lerner RA. Antibodies of predetermined specificity in biology and medicine. Advances in Immunology. 36: 1-44. DOI: 10.1007/978-3-642-70926-5_4 |
0.461 |
|
| 1983 |
Alexander H, Johnson DA, Rosen J, Jerabek L, Green N, Weissman IL, Lerner RA. Mimicking the alloantigenicity of proteins with chemically synthesized peptides differing in single amino acids. Nature. 306: 697-9. PMID 6656870 DOI: 10.1038/306697A0 |
0.369 |
|
| 1983 |
Shinnick TM, Sutcliffe JG, Green N, Lerner RA. Synthetic peptide immunogens as vaccines. Annual Review of Microbiology. 37: 425-46. PMID 6357058 DOI: 10.1146/Annurev.Mi.37.100183.002233 |
0.577 |
|
| 1983 |
Rowlands DJ, Clarke BE, Carroll AR, Brown F, Nicholson BH, Bittle JL, Houghten RA, Lerner RA. Chemical basis of antigenic variation in foot-and-mouth disease virus Nature. 306: 694-697. PMID 6318114 DOI: 10.1038/306694A0 |
0.308 |
|
| 1983 |
Luka J, Sternas L, Jornvall H, Klein G, Lerner R. Antibodies of predetermined specificity for the NH2 terminus of a cellular protein p53 react with the native molecule: evidence for the presence of different p53s. Proceedings of the National Academy of Sciences of the United States of America. 80: 1199-1203. PMID 6298784 DOI: 10.1073/Pnas.80.5.1199 |
0.442 |
|
| 1983 |
McMillan S, Seiden MV, Houghten RA, Clevinger B, Davie JM, Lerner RA. Synthetic idiotypes: the third hypervariable region of murine anti-dextran antibodies. Cell. 35: 859-63. PMID 6197187 DOI: 10.1016/0092-8674(83)90118-6 |
0.381 |
|
| 1983 |
Niman HL, Houghten RA, Walker LE, Reisfeld RA, Wilson IA, Hogle JM, Lerner RA. Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition. Proceedings of the National Academy of Sciences of the United States of America. 80: 4949-53. PMID 6192445 DOI: 10.1073/Pnas.80.16.4949 |
0.409 |
|
| 1983 |
Clarke BE, Carroll AR, Rowlands DJ, Nicholson BH, Houghten RA, Lerner RA, Brown F. Synthetic peptides mimic subtype specificity of foot-and-mouth disease virus Febs Letters. 157: 261-264. PMID 6190676 DOI: 10.1016/0014-5793(83)80558-4 |
0.336 |
|
| 1983 |
Gerin JL, Alexander H, Shih JW, Purcell RH, Dapolito G, Engle R, Green N, Sutcliffe JG, Shinnick TM, Lerner RA. Chemically synthesized peptides of hepatitis B surface antigen duplicate the d/y specificities and induce subtype-specific antibodies in chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 80: 2365-9. PMID 6188163 DOI: 10.1073/Pnas.80.8.2365 |
0.554 |
|
| 1983 |
Sutcliffe JG, Shinnick TM, Green N, Lerner RA. Antibodies that react with predetermined sites on proteins. Science (New York, N.Y.). 219: 660-6. PMID 6186024 DOI: 10.1126/Science.6186024 |
0.547 |
|
| 1982 |
Bittle JL, Houghten RA, Alexander H, Shinnick TM, Sutcliffe JG, Lerner RA, Rowlands DJ, Brown F. Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence. Nature. 298: 30-3. PMID 7045684 DOI: 10.1038/298030A0 |
0.558 |
|
| 1982 |
Sutcliffe JG, Milner RJ, Bloom FE, Lerner RA. Common 82-nucleotide sequence unique to brain RNA. Proceedings of the National Academy of Sciences of the United States of America. 79: 4942-6. PMID 6956902 DOI: 10.1073/Pnas.79.16.4942 |
0.482 |
|
| 1982 |
Green N, Alexander H, Olson A, Alexander S, Shinnick TM, Sutcliffe JG, Lerner RA. Immunogenic structure of the influenza virus hemagglutinin. Cell. 28: 477-87. PMID 6176330 DOI: 10.1016/0092-8674(82)90202-1 |
0.57 |
|
| 1982 |
Lerner RA. Tapping the immunological repertoire to produce antibodies of predetermined specificity Nature. 299: 592-600. DOI: 10.1038/299592A0 |
0.47 |
|
| 1981 |
Lerner RA, Sutcliffe JG, Shinnick TM. Antibodies to chemically synthesized peptides predicted from DNA sequences as probes of gene expression. Cell. 23: 309-10. PMID 7008951 DOI: 10.1016/0092-8674(81)90126-4 |
0.566 |
|
| 1981 |
Green N, Shinnick TM, Witte O, Ponticelli A, Sutcliffe JG, Lerner RA. Sequence-specific antibodies show that maturation of Moloney leukemia virus envelope polyprotein involves removal of a COOH-terminal peptide. Proceedings of the National Academy of Sciences of the United States of America. 78: 6023-7. PMID 6947213 DOI: 10.1073/Pnas.78.10.6023 |
0.569 |
|
| 1981 |
Sutcliffe JG, Shinnick TM, Lerner RA. Moloney murine leukemia virus is a transposon: nucleotide sequence analysis identifies genes and replication details. Cold Spring Harbor Symposia On Quantitative Biology. 45: 707-10. PMID 6266762 DOI: 10.1101/Sqb.1981.045.01.088 |
0.491 |
|
| 1981 |
Lerner RA, Green N, Olson A, Shinnick T, Sutcliffe JG. The development of synthetic vaccines. Hospital Practice (Office Ed.). 16: 55-62. PMID 6171500 DOI: 10.1080/21548331.1981.11946879 |
0.453 |
|
| 1981 |
Shinnick TM, Lerner RA, Sutcliffe JG. Nucleotide sequence of Moloney murine leukaemia virus. Nature. 293: 543-8. PMID 6169994 DOI: 10.1038/293543a0 |
0.427 |
|
| 1981 |
Lerner RA, Green N, Alexander H, Liu FT, Sutcliffe JG, Shinnick TM. Chemically synthesized peptides predicted from the nucleotide sequence of the hepatitis B virus genome elicit antibodies reactive with the native envelope protein of Dane particles. Proceedings of the National Academy of Sciences of the United States of America. 78: 3403-7. PMID 6167985 DOI: 10.1073/Pnas.78.6.3403 |
0.554 |
|
| 1980 |
Sutcliffe JG, Shinnick TM, Verma IM, Lerner RA. Nucleotide sequence of Moloney leukemia virus: 3' end reveals details of replications, analogy to bacterial transposons, and an unexpected gene. Proceedings of the National Academy of Sciences of the United States of America. 77: 3302-6. PMID 6251454 DOI: 10.1073/Pnas.77.6.3302 |
0.511 |
|
| 1980 |
Sutcliffe JG, Shinnick TM, Green N, Liu FT, Niman HL, Lerner RA. Chemical synthesis of a polypeptide predicted from nucleotide sequence allows detection of a new retroviral gene product. Nature. 287: 801-5. PMID 6159543 DOI: 10.1038/287801A0 |
0.541 |
|
| 1980 |
Sutcliffe JG, Shinnick TM, Lerner RA, Johnson P, Verma IM. Nucleotide sequence of a cloned murine leukemia virus DNA fragment. Cold Spring Harbor Symposia On Quantitative Biology. 44: 1275-9. PMID 6159135 DOI: 10.1101/Sqb.1980.044.01.139 |
0.494 |
|
| 1980 |
Geltosky JE, Weseman J, Bakke A, Lerner RA. Identification of a cell surface glycoprotein involved in cell aggregation in D. discoideum. Cell. 18: 391-8. PMID 498273 DOI: 10.1016/0092-8674(79)90058-8 |
0.327 |
|
| 1978 |
Fischinger PJ, Frankel AE, Elder JH, Lerner RA, Ihle JN, Bolognesi DP. Biological, immunological, and biochemical evidence that HIX virus is a recombinant between moloney leukemia virus and a murine xenotropic C type virus Virology. 90: 241-254. PMID 214945 DOI: 10.1016/0042-6822(78)90308-2 |
0.329 |
|
| 1977 |
Elder JH, Jensen FC, Bryant ML, Lerner RA. Polymorphism of the major envelope glycoprotein (gp70) of murine C-type viruses: Virion associated and differentiation antigens encoded by a multi-gene family Nature. 267: 23-28. PMID 193039 DOI: 10.1038/267023A0 |
0.3 |
|
| 1976 |
Levy RL, Lerner RA, Dixon FJ. Enhancement of infectivity and oncogenicity of a murine leukemia virus in adult mice by X-irradiation. Cancer Research. 36: 2090-5. PMID 178443 |
0.41 |
|
| 1976 |
Lerner RA, Wilson CB, Villano BC, McConahey PJ, Dixon FJ. Endogenous oncornaviral gene expression in adult and fetal mice: quantitative, histologic, and physiologic studies of the major viral glycorprotein, gp70. The Journal of Experimental Medicine. 143: 151-66. PMID 172586 DOI: 10.1084/Jem.143.1.151 |
0.484 |
|
| 1975 |
Kennel SJ, delVillano BC, Levy RL, Lerner RA. Biochemical and immunologic characterization of an oncornavirus glycoprotein. Bibliotheca Haematologica. 329-38. PMID 169812 DOI: 10.1159/000397550 |
0.319 |
|
| 1975 |
Del Vellano BC, Nave B, Croker BP, Lerner RA, Dixon FJ. The oncornavirus glycoprotein gp69/71: a constituent of the surface of normal and malignant thymocytes. The Journal of Experimental Medicine. 141: 172-87. PMID 46909 DOI: 10.1084/Jem.141.1.172 |
0.547 |
|
| 1974 |
Croker BP, del Villano BC, Jensen FC, Lerner RA, Dixon FJ. Immunopathogenicity and oncogenicity of murine leukemia viruses. I. Induction of immunologic disease and lymphoma in (BALB-c times NZB)F1 mice by Scripps leukemia virus. The Journal of Experimental Medicine. 140: 1028-48. PMID 4372290 DOI: 10.1084/Jem.140.4.1028 |
0.515 |
|
| 1973 |
Lerner RA, Dixon FJ. The human lymphocyte as an experimental animal. Scientific American. 228: 82-91. PMID 4722236 DOI: 10.1038/Scientificamerican0673-82 |
0.461 |
|
| 1973 |
Kennel SJ, Del Villano BC, Levy RL, Lerner RA. Properties of an oncornavirus glycoprotein: evidence for its presence on the surface of virions and infected cells. Virology. 55: 464-75. PMID 4200514 DOI: 10.1016/0042-6822(73)90188-8 |
0.354 |
|
| 1972 |
Lerner RA, McConahey PJ, Jansen I, Dixon FJ. Synthesis of plasma membrane-associated and secretory immunoglobulin in diploid lymphocytes. The Journal of Experimental Medicine. 135: 136-49. PMID 5061901 DOI: 10.1084/Jem.135.1.136 |
0.484 |
|
| 1972 |
Ferrone S, Del Villano BC, Pellegrino MA, Lerner RA, Reisfeld RA. Expression of HL-A antigens on the surface of cultured human lymphoid cells: effect of inhibitors of protein and nucleic acid synthesis. Tissue Antigens. 2: 447-53. PMID 4648386 DOI: 10.1111/J.1399-0039.1972.Tb00065.X |
0.336 |
|
| 1972 |
Lerner RA, Jensen F, Kennel SJ, Dixon FJ, Des Roches G, Francke U. Karyotypic, virologic, and immunologic analyses of two continuous lymphocyte lines established from New Zealand black mice: possible relationship of chromosomal mosaicism to autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 69: 2965-9. PMID 4342970 DOI: 10.1073/Pnas.69.10.2965 |
0.487 |
|
| 1971 |
Lerner RA, McConahey PJ, Dixon FJ. Quantitative aspects of plasma membrane-associated immunoglobulin in clones of diploid human lymphocytes. Science (New York, N.Y.). 173: 60-2. PMID 5087481 DOI: 10.1126/Science.173.3991.60 |
0.491 |
|
| 1971 |
Lerner RA, Oldstone MB, Cooper NR. Cell cycle-dependent immune lysis of Moloney virus-transformed lymphocytes: presence of viral antigen, accessibility to antibody, and complement activation. Proceedings of the National Academy of Sciences of the United States of America. 68: 2584-8. PMID 4944633 DOI: 10.1073/Pnas.68.10.2584 |
0.577 |
|
| 1969 |
Dixon FJ, McPhaul JJ, Lerner RA. The contribution of kidney transplantation o the study of glomerulonephritis--the recurrence of glomerulonephritis in renal transplants. Transplantation Proceedings. 1: 194-6. PMID 4944217 |
0.367 |
|
| 1968 |
Lerner RA, McPhaul JJ, Dixon FJ. Soluble glomerular basement membrane antigens in normal urine--possible autoimmunogens in man. Annals of Internal Medicine. 68: 249-50. PMID 5299824 DOI: 10.7326/0003-4819-68-1-249 |
0.556 |
|
| 1968 |
Starzl TE, Lerner RA, Dixon FJ, Groth CG, Brettschneider L, Terasaki PI. Shwartzman reaction after human renal homotransplantation. The New England Journal of Medicine. 278: 642-8. PMID 4866352 DOI: 10.1056/NEJM196803212781202 |
0.476 |
|
| 1968 |
Lerner RA, Dixon FJ. The induction of acute glomerulonephritis in rabbits with soluble antigens isolated from normal homologous and autologous urine. Journal of Immunology (Baltimore, Md. : 1950). 100: 1277-87. PMID 4177027 |
0.47 |
|
| 1968 |
Lerner RA, Dixon FJ, Lee S. Spontaneous glomerulonephritis in sheep. II. Studies on natural history, occurrence in other species, and pathogenesis. The American Journal of Pathology. 53: 501-12. PMID 4175664 |
0.379 |
|
| 1967 |
Lerner RA, Glassock RJ, Dixon FJ. The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis. The Journal of Experimental Medicine. 126: 989-1004. PMID 4964566 DOI: 10.1084/Jem.126.6.989 |
0.617 |
|
| 1966 |
Lerner RA, Dixon FJ. Spontaneous glomerulonephritis in sheep. Laboratory Investigation; a Journal of Technical Methods and Pathology. 15: 1279-89. PMID 5949954 |
0.384 |
|
| 1966 |
Lerner RA, Dixon FJ. Transfer of ovine experimental allergic glomerulonephritis (EAG) with serum. The Journal of Experimental Medicine. 124: 431-42. PMID 5922743 DOI: 10.1084/Jem.124.3.431 |
0.541 |
|
| Show low-probability matches. |
