Vera Y. Moiseenkova-Bell, Ph.D. - Publications

Affiliations: 
Department of Systems Pharmacology and Translational Therapeutics University of Pennsylvania Medical School, Philadelphia, PA, United States 
Area:
Molecular mechanisms and structural basis of pain sensation.
Website:
https://moiseenkova-lab.com/

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gallo PN, Mihelc E, Eisert R, Bradshaw GA, Dimek F, Leffler A, Kalocsay M, Moiseenkova-Bell V. The dynamic TRPV2 ion channel proximity proteome reveals functional links of calcium flux with cellular adhesion factors NCAM and L1CAM in neurite outgrowth. Cell Calcium. 121: 102894. PMID 38728789 DOI: 10.1016/j.ceca.2024.102894  0.365
2024 Haug FM, Pumroy RA, Sridhar A, Pantke S, Dimek F, Fricke TC, Hage A, Herzog C, Echtermeyer FG, de la Roche J, Koh A, Kotecha A, Howard RJ, Lindahl E, Moiseenkova-Bell V, et al. Functional and structural insights into activation of TRPV2 by weak acids. The Embo Journal. PMID 38671253 DOI: 10.1038/s44318-024-00106-4  0.322
2024 Pumroy RA, De Jesús-Pérez JJ, Protopopova AD, Rocereta JA, Fluck EC, Fricke T, Lee BH, Rohacs T, Leffler A, Moiseenkova-Bell V. Molecular details of ruthenium red pore block in TRPV channels. Embo Reports. PMID 38225355 DOI: 10.1038/s44319-023-00050-0  0.461
2023 De Jesús-Pérez JJ, Gabrielle M, Raheem S, Fluck EC, Rohacs T, Moiseenkova-Bell VY. Structural mechanism of TRPV5 inhibition by econazole. Structure (London, England : 1993). PMID 38141613 DOI: 10.1016/j.str.2023.11.012  0.322
2023 Sanganna Gari RR, Tagiltsev G, Pumroy RA, Jiang Y, Blackledge M, Moiseenkova-Bell VY, Scheuring S. Intrinsically disordered regions in TRPV2 mediate protein-protein interactions. Communications Biology. 6: 966. PMID 37736816 DOI: 10.1038/s42003-023-05343-7  0.569
2023 Lee BH, De Jesús Pérez JJ, Moiseenkova-Bell V, Rohacs T. Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A. Nature Communications. 14: 5883. PMID 37735536 DOI: 10.1038/s41467-023-41577-z  0.52
2022 Feng S, Pumroy RA, Protopopova AD, Moiseenkova-Bell VY, Im W. Modulation of TRPV2 by Endogenous and Exogenous Ligands: A Computational Study. Protein Science : a Publication of the Protein Society. e4490. PMID 36327382 DOI: 10.1002/pro.4490  0.397
2022 Rohacs T, Fluck EC, De Jesús-Pérez JJ, Moiseenkova-Bell VY. What structures did, and did not, reveal about the function of the epithelial Ca channels TRPV5 and TRPV6. Cell Calcium. 106: 102620. PMID 35834842 DOI: 10.1016/j.ceca.2022.102620  0.606
2022 Pumroy RA, Protopopova AD, Fricke TC, Lange IU, Haug FM, Nguyen PT, Gallo PN, Sousa BB, Bernardes GJL, Yarov-Yarovoy V, Leffler A, Moiseenkova-Bell VY. Structural insights into TRPV2 activation by small molecules. Nature Communications. 13: 2334. PMID 35484159 DOI: 10.1038/s41467-022-30083-3  0.363
2022 Fluck EC, Yazici AT, Rohacs T, Moiseenkova-Bell VY. Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Reports. 39: 110737. PMID 35476976 DOI: 10.1016/j.celrep.2022.110737  0.484
2021 Ahmed T, Nisler CR, Fluck EC, Walujkar S, Sotomayor M, Moiseenkova-Bell VY. Structure of the ancient TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium. Structure (London, England : 1993). PMID 34453887 DOI: 10.1016/j.str.2021.08.003  0.619
2021 Moiseenkova-Bell V, Delemotte L, Minor DL. Ion channels: Intersection of Structure, Function, and Pharmacology. Journal of Molecular Biology. 167102. PMID 34119491 DOI: 10.1016/j.jmb.2021.167102  0.471
2021 Fluck EC, Pumroy RA, Moiseenkova-Bell VY. Production and purification of TRPV2 and TRPV5 for structural and functional studies. Methods in Enzymology. 653: 49-74. PMID 34099181 DOI: 10.1016/bs.mie.2021.02.007  0.55
2021 Conde J, Pumroy RA, Baker C, Rodrigues T, Guerreiro A, Sousa BB, Marques MC, de Almeida BP, Lee S, Leites EP, Picard D, Samanta A, Vaz SH, Sieglitz F, Langini M, ... ... Moiseenkova-Bell VY, et al. Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression. Acs Central Science. 7: 868-881. PMID 34079902 DOI: 10.1021/acscentsci.1c00070  0.349
2021 Zhao Y, McVeigh BM, Moiseenkova-Bell VY. Structural Pharmacology of TRP Channels. Journal of Molecular Biology. 166914. PMID 33676926 DOI: 10.1016/j.jmb.2021.166914  0.585
2020 Pumroy RA, Fluck EC, Ahmed T, Moiseenkova-Bell VY. Structural insights into the gating mechanisms of TRPV channels. Cell Calcium. 87: 102168. PMID 32004816 DOI: 10.1016/j.ceca.2020.102168  0.602
2019 Hughes TE, Del Rosario JS, Kapoor A, Yazici AT, Yudin Y, Fluck EC, Filizola M, Rohacs T, Moiseenkova-Bell VY. Structure-based characterization of novel TRPV5 inhibitors. Elife. 8. PMID 31647410 DOI: 10.7554/Elife.49572  0.431
2019 Pumroy RA, Samanta A, Liu Y, Hughes TE, Zhao S, Yudin Y, Rohacs T, Han S, Moiseenkova-Bell VY. Molecular mechanism of TRPV2 channel modulation by cannabidiol. Elife. 8. PMID 31566564 DOI: 10.7554/eLife.48792  0.558
2019 Samanta A, Hughes TET, Moiseenkova-Bell VY. Cryo Electron Microscopy of TRP Channels. Methods in Molecular Biology (Clifton, N.J.). 1987: 39-50. PMID 31028672 DOI: 10.1007/978-1-4939-9446-5_3  0.37
2018 Hughes TET, Pumroy RA, Yazici AT, Kasimova MA, Fluck EC, Huynh KW, Samanta A, Molugu SK, Zhou ZH, Carnevale V, Rohacs T, Moiseenkova-Bell VY. Structural insights on TRPV5 gating by endogenous modulators. Nature Communications. 9: 4198. PMID 30305626 DOI: 10.1038/s41467-018-06753-6  0.472
2018 Samanta A, Kiselar J, Pumroy RA, Han S, Moiseenkova-Bell VY. Structural insights into the molecular mechanism of mouse TRPA1 activation and inhibition. The Journal of General Physiology. PMID 29703838 DOI: 10.1085/jgp.201711876  0.607
2018 Samanta A, Hughes TET, Moiseenkova-Bell VY. Transient Receptor Potential (TRP) Channels. Sub-Cellular Biochemistry. 87: 141-165. PMID 29464560 DOI: 10.1007/978-981-10-7757-9_6  0.596
2018 Basak S, Gicheru Y, Samanta A, Molugu SK, Huang W, Fuente M, Hughes T, Taylor DJ, Nieman MT, Moiseenkova-Bell V, Chakrapani S. Cryo-EM structure of 5-HT3A receptor in its resting conformation. Nature Communications. 9: 514. PMID 29410406 DOI: 10.1038/s41467-018-02997-4  0.368
2018 Hughes TET, Lodowski DT, Huynh KW, Yazici A, Del Rosario J, Kapoor A, Basak S, Samanta A, Han X, Chakrapani S, Zhou ZH, Filizola M, Rohacs T, Han S, Moiseenkova-Bell VY. Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM. Nature Structural & Molecular Biology. 25: 53-60. PMID 29323279 DOI: 10.1038/S41594-017-0009-1  0.667
2016 Huynh KW, Cohen MR, Jiang J, Samanta A, Lodowski DT, Zhou ZH, Moiseenkova-Bell VY. Structure of the full-length TRPV2 channel by cryo-EM. Nature Communications. 7: 11130. PMID 27021073 DOI: 10.1038/ncomms11130  0.637
2015 Cohen MR, Johnson WM, Pilat JM, Kiselar J, DeFrancesco-Lisowitz A, Zigmond RE, Moiseenkova-Bell VY. NGF regulates TRPV2 via ERK signaling to enhance neurite outgrowth in developing neurons. Molecular and Cellular Biology. PMID 26416880 DOI: 10.1128/Mcb.00549-15  0.403
2014 Cohen MR, Moiseenkova-Bell VY. Structure of thermally activated TRP channels. Current Topics in Membranes. 74: 181-211. PMID 25366237 DOI: 10.1016/B978-0-12-800181-3.00007-5  0.49
2014 Huynh KW, Cohen MR, Moiseenkova-Bell VY. Application of amphipols for structure-functional analysis of TRP channels. The Journal of Membrane Biology. 247: 843-51. PMID 24894720 DOI: 10.1007/s00232-014-9684-6  0.596
2014 Huynh KW, Cohen MR, Chakrapani S, Holdaway HA, Stewart PL, Moiseenkova-Bell VY. Structural insight into the assembly of TRPV channels. Structure (London, England : 1993). 22: 260-8. PMID 24373766 DOI: 10.1016/j.str.2013.11.008  0.615
2013 Cohen MR, Huynh KW, Cawley D, Moiseenkova-Bell VY. Understanding the cellular function of TRPV2 channel through generation of specific monoclonal antibodies. Plos One. 8: e85392. PMID 24392006 DOI: 10.1371/journal.pone.0085392  0.362
2012 Wang L, Cvetkov TL, Chance MR, Moiseenkova-Bell VY. Identification of in vivo disulfide conformation of TRPA1 ion channel. The Journal of Biological Chemistry. 287: 6169-76. PMID 22207754 DOI: 10.1074/Jbc.M111.329748  0.411
2011 Cvetkov TL, Huynh KW, Cohen MR, Moiseenkova-Bell VY. Molecular architecture and subunit organization of TRPA1 ion channel revealed by electron microscopy. The Journal of Biological Chemistry. 286: 38168-76. PMID 21908607 DOI: 10.1074/jbc.M111.288993  0.505
2011 Ludtke SJ, Tran TP, Ngo QT, Moiseenkova-Bell VY, Chiu W, Serysheva II. Flexible architecture of IP3R1 by Cryo-EM. Structure (London, England : 1993). 19: 1192-9. PMID 21827954 DOI: 10.1016/J.Str.2011.05.003  0.585
2011 Moiseenkova-Bell V, Wensel TG. Functional and structural studies of TRP channels heterologously expressed in budding yeast. Advances in Experimental Medicine and Biology. 704: 25-40. PMID 21290288 DOI: 10.1007/978-94-007-0265-3_2  0.645
2010 Goc A, Chami M, Lodowski DT, Bosshart P, Moiseenkova-Bell V, Baehr W, Engel A, Palczewski K. Structural characterization of the rod cGMP phosphodiesterase 6. Journal of Molecular Biology. 401: 363-73. PMID 20600113 DOI: 10.1016/J.Jmb.2010.06.044  0.345
2009 Yao CK, Lin YQ, Ly CV, Ohyama T, Haueter CM, Moiseenkova-Bell VY, Wensel TG, Bellen HJ. A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis. Cell. 138: 947-60. PMID 19737521 DOI: 10.1016/J.Cell.2009.06.033  0.557
2009 Moiseenkova-Bell VY, Wensel TG. Hot on the trail of TRP channel structure. The Journal of General Physiology. 133: 239-44. PMID 19237588 DOI: 10.1085/Jgp.200810123  0.642
2009 Moiseenkova-Bell V, Chen B, Tobe B, Serysheva I, Wensel T. Molecular Basis of Calmodulin and Ca2+ interaction with thermoTRP channels Biophysical Journal. 96: 267a. DOI: 10.1016/J.Bpj.2008.12.1318  0.625
2008 Moiseenkova-Bell VY, Stanciu LA, Serysheva II, Tobe BJ, Wensel TG. Structure of TRPV1 channel revealed by electron cryomicroscopy. Proceedings of the National Academy of Sciences of the United States of America. 105: 7451-5. PMID 18490661 DOI: 10.1073/Pnas.0711835105  0.632
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