| Year |
Citation |
Score |
| 2022 |
Kang F, Xie L, Qin T, Miao Y, Kang Y, Takahashi T, Liang T, Xie H, Gaisano HY. Plasma membrane flipping of Syntaxin-2 regulates its inhibitory action on insulin granule exocytosis. Nature Communications. 13: 6512. PMID 36316316 DOI: 10.1038/s41467-022-33986-3 |
0.378 |
|
| 2020 |
Takahashi T, Miao Y, Kang F, Dolai S, Gaisano HY. Susceptibility Factors And Cellular Mechanisms Underlying Alcoholic Pancreatitis. Alcoholism, Clinical and Experimental Research. PMID 32056245 DOI: 10.1111/Acer.14304 |
0.315 |
|
| 2020 |
Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, Ostenson CG, Kieffer TJ, Banks K, Pessin JE, ... Gaisano HY, et al. SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes. Jci Insight. 5. PMID 32051343 DOI: 10.1172/Jci.Insight.129694 |
0.486 |
|
| 2020 |
Wen J, Cai X, Zhang J, Jiang J, Li W, Liu G, Wang M, Gaisano HY, Pan Y, He Y. Relation of adipose tissue insulin resistance to prediabetes. Endocrine. PMID 31925734 DOI: 10.1007/S12020-020-02186-8 |
0.331 |
|
| 2019 |
Thurmond DC, Gaisano HY. Recent insights into beta-cell exocytosis in type 2 diabetes. Journal of Molecular Biology. PMID 31863749 DOI: 10.1016/J.Jmb.2019.12.012 |
0.421 |
|
| 2019 |
Cornick S, Kumar M, Moreau F, Gaisano H, Chadee K. VAMP8-mediated MUC2 mucin exocytosis from colonic goblet cells maintains innate intestinal homeostasis. Nature Communications. 10: 4306. PMID 31541089 DOI: 10.1038/S41467-019-11811-8 |
0.306 |
|
| 2019 |
Luck H, Khan S, Kim JH, Copeland JK, Revelo XS, Tsai S, Chakraborty M, Cheng K, Tao Chan Y, Nøhr MK, Clemente-Casares X, Perry MC, Ghazarian M, Lei H, Lin YH, ... ... Gaisano H, et al. Gut-associated IgA immune cells regulate obesity-related insulin resistance. Nature Communications. 10: 3650. PMID 31409776 DOI: 10.1038/S41467-019-11370-Y |
0.347 |
|
| 2019 |
Piplani H, Marek-Iannucci S, Sin J, Hou J, Takahashi T, Sharma A, de Freitas Germano J, Waldron RT, Saadaeijahromi H, Song Y, Gulla A, Wu B, Lugea A, Andres AM, Gaisano HY, et al. Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 31398467 DOI: 10.1016/J.Bbadis.2019.08.006 |
0.34 |
|
| 2019 |
Fu J, Githaka JM, Dai X, Plummer G, Suzuki K, Spigelman AF, Bautista A, Kim R, Greitzer-Antes D, Manning Fox JE, Gaisano HY, MacDonald PE. A glucose-dependent spatial patterning of exocytosis in human β-cells is disrupted in type 2 diabetes. Jci Insight. 5. PMID 31085831 DOI: 10.1172/jci.insight.127896 |
0.353 |
|
| 2018 |
Liu G, Dou J, Pan Y, Yan Y, Zhu H, Lu J, Gaisano H, Ji L, He Y. Comparison of the Effect of Glycemic Control in Type 2 Diabetes Outpatients Treated With Premixed and Basal Insulin Monotherapy in China. Frontiers in Endocrinology. 9: 639. PMID 30420835 DOI: 10.3389/Fendo.2018.00639 |
0.388 |
|
| 2018 |
Zheng D, Dou J, Liu G, Pan Y, Yan Y, Liu F, Gaisano HY, Lu J, He Y. Association Between Triglyceride Level and Glycemic Control Among Insulin-treated Patients With Type 2 Diabetes. The Journal of Clinical Endocrinology and Metabolism. PMID 30418583 DOI: 10.1210/Jc.2018-01656 |
0.315 |
|
| 2018 |
Bin NR, Ma K, Tien CW, Wang S, Zhu D, Park S, Turlova E, Sugita K, Shirakawa R, van der Sluijs P, Horiuchi H, Sun HS, Monnier PP, Gaisano HY, Sugita S. C2 Domains of Munc13-4 Are Crucial for Ca-Dependent Degranulation and Cytotoxicity in NK Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 29884704 DOI: 10.4049/Jimmunol.1800426 |
0.338 |
|
| 2018 |
Greitzer-Antes D, Xie L, Qin T, Xie H, Zhu D, Dolai S, Liang T, Kang F, Hardy AB, He Y, Kang Y, Gaisano HY. Kv2.1 clusters on β-cell plasma membrane act as reservoirs that replenish pools of newcomer insulin granule through their interaction with syntaxin-3. The Journal of Biological Chemistry. PMID 29549124 DOI: 10.1074/Jbc.Ra118.002703 |
0.463 |
|
| 2018 |
Dolai S, Liang T, Orabi AI, Holmyard D, Xie L, Greitzer-Antes D, Kang Y, Xie H, Javed TA, Lam PP, Rubin DC, Thorn P, Gaisano HY. Pancreatitis-induced Depletion of Syntaxin 2 Promotes Autophagy and Increases Basolateral Exocytosis. Gastroenterology. PMID 29360461 DOI: 10.1053/J.Gastro.2018.01.025 |
0.434 |
|
| 2017 |
Dolai S, Liang T, Orabi AI, Xie L, Holmyard D, Javed TA, Fernandez NA, Xie H, Cattral MS, Thurmond DC, Thorn P, Gaisano HY. Munc18c depletion attenuates caerulein hyperstimulation induced pancreatitis. The Journal of Biological Chemistry. PMID 29284677 DOI: 10.1074/Jbc.Ra117.000792 |
0.442 |
|
| 2017 |
Cornick S, Moreau F, Gaisano HY, Chadee K. VAMP8 mucin exocytosis attenuates intestinal pathogenesis by Entamoeba histolytica. Microbial Cell (Graz, Austria). 4: 426-427. PMID 29234672 DOI: 10.15698/Mic2017.12.605 |
0.322 |
|
| 2017 |
Cornick S, Moreau F, Gaisano HY, Chadee K. Entamoeba histolytica-Induced Mucin Exocytosis Is Mediated by VAMP8 and Is Critical in Mucosal Innate Host Defense. Mbio. 8. PMID 28974617 DOI: 10.1128/Mbio.01323-17 |
0.371 |
|
| 2017 |
Makhmutova M, Liang T, Gaisano H, Caicedo A, Almaça J. Confocal Imaging of Neuropeptide Y-pHluorin: A Technique to Visualize Insulin Granule Exocytosis in Intact Murine and Human Islets. Journal of Visualized Experiments : Jove. PMID 28930993 DOI: 10.3791/56089 |
0.421 |
|
| 2017 |
Gaisano HY. Recent new insights into the role of SNARE and associated proteins in insulin granule exocytosis. Diabetes, Obesity & Metabolism. 19: 115-123. PMID 28880475 DOI: 10.1111/Dom.13001 |
0.458 |
|
| 2017 |
Fu J, Dai X, Plummer G, Suzuki K, Bautista A, Githaka JM, Senior L, Jensen M, Greitzer-Antes D, Manning Fox JE, Gaisano HY, Newgard CB, Touret N, MacDonald PE. Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction. Diabetes. PMID 28607108 DOI: 10.2337/Db16-1170 |
0.463 |
|
| 2017 |
Wheeler SE, Stacey HM, Nahaei Y, Hale SJ, Hardy AB, Reimann F, Gribble FM, Larraufie P, Gaisano HY, Brubaker PL. The SNARE Protein, Syntaxin1a, Plays an Essential Role in Biphasic Exocytosis of the Incretin Hormone, Glucagon-Like Peptide-1. Diabetes. PMID 28596237 DOI: 10.2337/Db16-1403 |
0.44 |
|
| 2017 |
Liang T, Dolai S, Xie L, Winter E, Orabi AI, Karimian N, Cosen-Binker LI, Huang YC, Thorn P, Cattral M, Gaisano HY. Ex Vivo Human Pancreatic Slice Preparations Offer a Valuable Model for Studying Pancreatic Exocrine Biology. The Journal of Biological Chemistry. PMID 28242761 DOI: 10.1074/Jbc.M117.777433 |
0.698 |
|
| 2017 |
Qin T, Liang T, Zhu D, Kang Y, Xie L, Dolai S, Sugita S, Takahashi N, Ostenson CG, Banks K, Gaisano HY. Munc18b Increases Insulin Granule Fusion, Restoring Deficient Insulin Secretion in Type-2 Diabetes Human and Goto-Kakizaki Rat Islets with Improvement in Glucose Homeostasis. Ebiomedicine. PMID 28163042 DOI: 10.1016/J.Ebiom.2017.01.030 |
0.443 |
|
| 2017 |
Zhu D, Xie L, Kang Y, Dolai S, Hansen JB, Qin T, Xie H, Liang T, Rubin DC, Osborne L, Gaisano HY. Syntaxin 2 Acts as Inhibitory SNARE for Insulin Granule Exocytosis. Diabetes. PMID 28115395 DOI: 10.2337/Db16-0636 |
0.481 |
|
| 2017 |
Pan Y, Jing J, Chen W, Zheng H, Jia Q, Mi D, Li H, Zhao X, Liu L, Wang C, Gaisano HY, He Y, Wang Y, Wang Y. Post-Glucose Load Measures of Insulin Resistance and Prognosis of Nondiabetic Patients With Ischemic Stroke. Journal of the American Heart Association. 6. PMID 28108466 DOI: 10.1161/Jaha.116.004990 |
0.321 |
|
| 2017 |
Binker-Cosen MJ, Richards D, Oliver B, Gaisano HY, Binker MG, Cosen-Binker LI. Palmitic acid increases invasiveness of pancreatic cancer cells AsPC-1 through TLR4/ROS/NF-κB/MMP-9 signaling pathway. Biochemical and Biophysical Research Communications. PMID 28088520 DOI: 10.1016/J.Bbrc.2017.01.051 |
0.308 |
|
| 2016 |
Liang T, Qin T, Xie L, Dolai S, Zhu D, Prentice KJ, Wheeler M, Kang Y, Osborne L, Gaisano HY. New roles of Syntaxin-1A in insulin granule exocytosis and replenishment. The Journal of Biological Chemistry. PMID 28031464 DOI: 10.1074/Jbc.M116.769885 |
0.385 |
|
| 2016 |
Dolai S, Xie L, Zhu D, Liang T, Qin T, Xie H, Kang Y, Chapman ER, Gaisano HY. Synaptotagmin-7 functions to replenish insulin granules for exocytosis in human islet β-cell. Diabetes. PMID 27207520 DOI: 10.2337/Db15-1436 |
0.475 |
|
| 2016 |
Do OH, Gunton JE, Gaisano HY, Thorn P. Changes in beta cell function occur in prediabetes and early disease in the Lepr (db) mouse model of diabetes. Diabetologia. 59: 1222-30. PMID 27048248 DOI: 10.1007/S00125-016-3942-3 |
0.4 |
|
| 2016 |
Gan WJ, Zavortink M, Ludick C, Templin R, Webb R, Webb R, Ma W, Poronnik P, Parton RG, Gaisano HY, Shewan AM, Thorn P. Cell polarity defines three distinct domains in pancreatic beta cells. Journal of Cell Science. PMID 26919978 DOI: 10.1242/Jcs.185116 |
0.345 |
|
| 2016 |
Xie L, Dolai S, Kang Y, Liang T, Xie H, Qin T, Yang L, Chen L, Gaisano HY. Syntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells. Plos One. 11: e0147862. PMID 26848587 DOI: 10.1371/Journal.Pone.0147862 |
0.412 |
|
| 2015 |
Thorn P, Gaisano HY. Cell-to-Cell Communication and the Regulation of Pancreatic Function. Pancreas. 44: 1174-5. PMID 26465945 DOI: 10.1097/Mpa.0000000000000401 |
0.358 |
|
| 2015 |
Almaça J, Liang T, Gaisano HY, Nam HG, Berggren PO, Caicedo A. Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets. Diabetologia. PMID 26376795 DOI: 10.1007/S00125-015-3747-9 |
0.452 |
|
| 2015 |
Dai FF, Bhattacharjee A, Liu Y, Batchuluun B, Zhang M, Wang XS, Huang X, Luu L, Zhu D, Gaisano H, Wheeler MB. A novel GLP-1 receptor interacting protein ATP6ap2 regulates insulin secretion in pancreatic beta cells. The Journal of Biological Chemistry. PMID 26272612 DOI: 10.1074/Jbc.M115.648592 |
0.502 |
|
| 2015 |
Binker MG, Richards D, Gaisano HY, Cosen-Binker LI. ER stress-associated CTRC mutants decrease stimulated pancreatic zymogen secretion through SIRT2-mediated microtubule dysregulation. Biochemical and Biophysical Research Communications. 463: 329-35. PMID 26022124 DOI: 10.1016/J.Bbrc.2015.05.064 |
0.374 |
|
| 2015 |
Zhu D, Xie L, Karimian N, Liang T, Kang Y, Huang YC, Gaisano HY. Munc18c mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose stimulated insulin secretion in human pancreatic beta-cells. Molecular Metabolism. 4: 418-26. PMID 25973389 DOI: 10.1016/J.Molmet.2015.02.004 |
0.746 |
|
| 2015 |
Liu Y, Batchuluun B, Ho L, Zhu D, Prentice KJ, Bhattacharjee A, Zhang M, Pourasgari F, Hardy AB, Taylor KM, Gaisano H, Dai FF, Wheeler MB. Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION. The Journal of Biological Chemistry. 290: 18757-69. PMID 25969539 DOI: 10.1074/Jbc.M115.640524 |
0.462 |
|
| 2015 |
Shao W, Xiong X, Ip W, Xu F, Song Z, Zeng K, Hernandez M, Liang T, Weng J, Gaisano H, Nostro MC, Jin T. The expression of dominant negative TCF7L2 in pancreatic beta cells during the embryonic stage causes impaired glucose homeostasis. Molecular Metabolism. 4: 344-52. PMID 25830097 DOI: 10.1016/J.Molmet.2015.01.008 |
0.38 |
|
| 2015 |
Bin NR, Jung CH, Kim B, Chandrasegram P, Turlova E, Zhu D, Gaisano HY, Sun HS, Sugita S. Chaperoning of closed syntaxin-3 through Lys46 and Glu59 in domain 1 of Munc18 proteins is indispensable for mast cell exocytosis. Journal of Cell Science. 128: 1946-60. PMID 25795302 DOI: 10.1242/Jcs.165662 |
0.365 |
|
| 2015 |
Xie L, Zhu D, Dolai S, Liang T, Qin T, Kang Y, Xie H, Huang YC, Gaisano HY. Syntaxin-4 mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose-stimulated insulin secretion in human pancreatic beta cells. Diabetologia. 58: 1250-9. PMID 25762204 DOI: 10.1007/S00125-015-3545-4 |
0.74 |
|
| 2015 |
Wang L, Luk CT, Cai EP, Schroer SA, Allister EM, Shi SY, Wheeler MB, Gaisano HY, Woo M. PTEN deletion in pancreatic α-cells protects against high-fat diet-induced hyperglucagonemia and insulin resistance. Diabetes. 64: 147-57. PMID 25092678 DOI: 10.2337/Db13-1715 |
0.411 |
|
| 2014 |
Messenger SW, Falkowski MA, Thomas DD, Jones EK, Hong W, Gaisano HY, Giasano HY, Boulis NM, Groblewski GE. Vesicle associated membrane protein 8 (VAMP8)-mediated zymogen granule exocytosis is dependent on endosomal trafficking via the constitutive-like secretory pathway. The Journal of Biological Chemistry. 289: 28040-53. PMID 25138214 DOI: 10.1074/Jbc.M114.593913 |
0.36 |
|
| 2014 |
Zhang M, Robitaille M, Showalter AD, Huang X, Liu Y, Bhattacharjee A, Willard FS, Han J, Froese S, Wei L, Gaisano HY, Angers S, Sloop KW, Dai FF, Wheeler MB. Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells. Molecular & Cellular Proteomics : McP. 13: 3049-62. PMID 25044020 DOI: 10.1074/Mcp.M114.040196 |
0.406 |
|
| 2014 |
Wang L, Luk CT, Schroer SA, Smith AM, Li X, Cai EP, Gaisano H, MacDonald PE, Hao Z, Mak TW, Woo M. Dichotomous role of pancreatic HUWE1/MULE/ARF-BP1 in modulating beta cell apoptosis in mice under physiological and genotoxic conditions. Diabetologia. 57: 1889-98. PMID 24981769 DOI: 10.1007/S00125-014-3295-8 |
0.383 |
|
| 2014 |
Zhao S, Mugabo Y, Iglesias J, Xie L, Delghingaro-Augusto V, Lussier R, Peyot ML, Joly E, Taïb B, Davis MA, Brown JM, Abousalham A, Gaisano H, Madiraju SR, Prentki M. α/β-Hydrolase domain-6-accessible monoacylglycerol controls glucose-stimulated insulin secretion. Cell Metabolism. 19: 993-1007. PMID 24814481 DOI: 10.1016/J.Cmet.2014.04.003 |
0.451 |
|
| 2014 |
Low JT, Zavortink M, Mitchell JM, Gan WJ, Do OH, Schwiening CJ, Gaisano HY, Thorn P. Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature. Diabetologia. 57: 1655-63. PMID 24795086 DOI: 10.1007/S00125-014-3252-6 |
0.428 |
|
| 2014 |
Gaisano HY. Here come the newcomer granules, better late than never. Trends in Endocrinology and Metabolism: Tem. 25: 381-8. PMID 24746186 DOI: 10.1016/J.Tem.2014.03.005 |
0.48 |
|
| 2014 |
Do OH, Low JT, Gaisano HY, Thorn P. The secretory deficit in islets from db/db mice is mainly due to a loss of responding beta cells. Diabetologia. 57: 1400-9. PMID 24705605 DOI: 10.1007/S00125-014-3226-8 |
0.315 |
|
| 2014 |
Liang T, Xie L, Chao C, Kang Y, Lin X, Qin T, Xie H, Feng ZP, Gaisano HY. Phosphatidylinositol 4,5-biphosphate (PIP2) modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic β-cell ATP-sensitive potassium channels. The Journal of Biological Chemistry. 289: 6028-40. PMID 24429282 DOI: 10.1074/Jbc.M113.511808 |
0.307 |
|
| 2014 |
Li SK, Zhu D, Gaisano HY, Brubaker PL. Role of vesicle-associated membrane protein 2 in exocytosis of glucagon-like peptide-1 from the murine intestinal L cell. Diabetologia. 57: 809-18. PMID 24356748 DOI: 10.1007/S00125-013-3143-2 |
0.402 |
|
| 2013 |
Low JT, Mitchell JM, Do OH, Bax J, Rawlings A, Zavortink M, Morgan G, Parton RG, Gaisano HY, Thorn P. Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell. Diabetologia. 56: 2629-37. PMID 23995471 DOI: 10.1007/S00125-013-3019-5 |
0.479 |
|
| 2013 |
Xie L, Zhu D, Kang Y, Liang T, He Y, Gaisano HY. Exocyst sec5 regulates exocytosis of newcomer insulin granules underlying biphasic insulin secretion. Plos One. 8: e67561. PMID 23844030 DOI: 10.1371/Journal.Pone.0067561 |
0.487 |
|
| 2013 |
Karimian N, Qin T, Liang T, Osundiji M, Huang Y, Teich T, Riddell MC, Cattral MS, Coy DH, Vranic M, Gaisano HY. Somatostatin receptor type 2 antagonism improves glucagon counterregulation in biobreeding diabetic rats. Diabetes. 62: 2968-77. PMID 23630299 DOI: 10.2337/Db13-0164 |
0.699 |
|
| 2013 |
Allister EM, Robson-Doucette CA, Prentice KJ, Hardy AB, Sultan S, Gaisano HY, Kong D, Gilon P, Herrera PL, Lowell BB, Wheeler MB. UCP2 regulates the glucagon response to fasting and starvation. Diabetes. 62: 1623-33. PMID 23434936 DOI: 10.2337/Db12-0981 |
0.321 |
|
| 2013 |
Zhang YX, Liu Y, Dong J, Wang YX, Wang J, Zhuang GQ, Han SJ, Guo QQ, Luo YX, Zhang J, Peng XX, Zhang L, Yan YX, Yang XH, Wang H, ... ... Gaisano H, et al. An exploratory study of the association between KCNB1 rs1051295 and type 2 diabetes and its related traits in Chinese Han population. Plos One. 8: e56365. PMID 23431371 DOI: 10.1371/Journal.Pone.0056365 |
0.36 |
|
| 2013 |
Lam PP, Ohno M, Dolai S, He Y, Qin T, Liang T, Zhu D, Kang Y, Liu Y, Kauppi M, Xie L, Wan WC, Bin NR, Sugita S, Olkkonen VM, ... ... Gaisano HY, et al. Munc18b is a major mediator of insulin exocytosis in rat pancreatic β-cells. Diabetes. 62: 2416-28. PMID 23423569 DOI: 10.2337/Db12-1380 |
0.397 |
|
| 2013 |
Xie L, Kang Y, Liang T, Dolai S, Xie H, Parsaud L, Lopez JA, He Y, Chidambaram S, Lam PP, James DE, Sugita S, Gaisano HY. RalA GTPase tethers insulin granules to L- and R-type calcium channels through binding α2 δ-1 subunit. Traffic (Copenhagen, Denmark). 14: 428-39. PMID 23346930 DOI: 10.1111/Tra.12047 |
0.456 |
|
| 2013 |
Zhu D, Koo E, Kwan E, Kang Y, Park S, Xie H, Sugita S, Gaisano HY. Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells Diabetologia. 56: 359-369. PMID 23132338 DOI: 10.1007/s00125-012-2757-0 |
0.369 |
|
| 2013 |
Huang YC, Rupnik MS, Karimian N, Herrera PL, Gilon P, Feng ZP, Gaisano HY. In situ electrophysiological examination of pancreatic α cells in the streptozotocin-induced diabetes model, revealing the cellular basis of glucagon hypersecretion. Diabetes. 62: 519-30. PMID 23043159 DOI: 10.2337/Db11-0786 |
0.718 |
|
| 2012 |
Gaisano HY, Macdonald PE, Vranic M. Glucagon secretion and signaling in the development of diabetes. Frontiers in Physiology. 3: 349. PMID 22969729 DOI: 10.3389/Fphys.2012.00349 |
0.35 |
|
| 2012 |
Zhu D, Zhang Y, Lam PP, Dolai S, Liu Y, Cai EP, Choi D, Schroer SA, Kang Y, Allister EM, Qin T, Wheeler MB, Wang CC, Hong WJ, Woo M, ... Gaisano HY, et al. Dual role of VAMP8 in regulating insulin exocytosis and islet β cell growth. Cell Metabolism. 16: 238-49. PMID 22841572 DOI: 10.1016/J.Cmet.2012.07.001 |
0.352 |
|
| 2012 |
Xie L, Zhu D, Gaisano HY. Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets. Diabetologia. 55: 2693-2702. PMID 22814762 DOI: 10.1007/s00125-012-2640-z |
0.325 |
|
| 2012 |
Cai EP, Casimir M, Schroer SA, Luk CT, Shi SY, Choi D, Dai XQ, Hajmrle C, Spigelman AF, Zhu D, Gaisano HY, MacDonald PE, Woo M. In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking. Diabetes. 61: 1708-18. PMID 22498697 DOI: 10.2337/Db11-1344 |
0.454 |
|
| 2012 |
Thorn P, Gaisano H. Molecular control of compound Exocytosis: A key role for VAMP8. Communicative & Integrative Biology. 5: 61-3. PMID 22482012 DOI: 10.4161/Cib.18058 |
0.328 |
|
| 2012 |
Dai XQ, Manning Fox JE, Chikvashvili D, Casimir M, Plummer G, Hajmrle C, Spigelman AF, Kin T, Singer-Lahat D, Kang Y, Shapiro AM, Gaisano HY, Lotan I, Macdonald PE. The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function. Diabetologia. 55: 1709-20. PMID 22411134 DOI: 10.1007/S00125-012-2512-6 |
0.455 |
|
| 2012 |
Gaisano HY. Deploying insulin granule-granule fusion to rescue deficient insulin secretion in diabetes. Diabetologia. 55: 877-80. PMID 22307686 DOI: 10.1007/S00125-012-2483-7 |
0.441 |
|
| 2012 |
Lamont BJ, Li Y, Kwan E, Brown TJ, Gaisano H, Drucker DJ. Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice Journal of Clinical Investigation. 122: 388-402. PMID 22182839 DOI: 10.1172/Jci42497 |
0.401 |
|
| 2012 |
Liang T, Dolai S, Karimian N, Winter E, Cattral MS, Gaisano HY. 561 Physiological and Pathological Exocytosis in Acinar Cells Examined in Situ in Human Pancreas Slices Gastroenterology. 142: S-113. DOI: 10.1016/S0016-5085(12)60426-0 |
0.36 |
|
| 2012 |
Liu Y, Zhang Y, Zhu D, Cai EP, Choi D, Schroer SA, Lam PP, Kang Y, Woo M, Gaisano HY. VAMP8 Deletion Delays the Onset of Streptozotocin-Induced Hyperglycemia Canadian Journal of Diabetes. 36: 251-256. DOI: 10.1016/J.Jcjd.2012.07.469 |
0.416 |
|
| 2012 |
Karimian N, Qin T, Osundiji M, Huang Y, Liang T, Riddell M, Coy DH, Vranic M, Gaisano HY. Selective Somatostatin Receptor Type 2 Antagonism Prevents Hypoglycaemia In Type 1 Diabetic BB Rats Canadian Journal of Diabetes. 36: S57. DOI: 10.1016/J.Jcjd.2012.07.398 |
0.682 |
|
| 2011 |
Behrendorff N, Dolai S, Hong W, Gaisano HY, Thorn P. Vesicle-associated membrane protein 8 (VAMP8) is a SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) selectively required for sequential granule-to-granule fusion. The Journal of Biological Chemistry. 286: 29627-34. PMID 21733851 DOI: 10.1074/Jbc.M111.265199 |
0.382 |
|
| 2011 |
Huang YC, Gaisano HY, Leung YM. Electrophysiological identification of mouse islet α-cells: from isolated single α-cells to in situ assessment within pancreas slices. Islets. 3: 139-43. PMID 21623173 DOI: 10.4161/Isl.3.4.16166 |
0.702 |
|
| 2011 |
Chang N, Liang T, Lin X, Kang Y, Xie H, Feng ZP, Gaisano HY. Syntaxin-1A interacts with distinct domains within nucleotide-binding folds of sulfonylurea receptor 1 to inhibit beta-cell ATP-sensitive potassium channels. The Journal of Biological Chemistry. 286: 23308-18. PMID 21540180 DOI: 10.1074/Jbc.M111.217950 |
0.33 |
|
| 2011 |
Fernandez NA, Liang T, Gaisano HY. Live pancreatic acinar imaging of exocytosis using syncollin-pHluorin. American Journal of Physiology. Cell Physiology. 300: C1513-23. PMID 21307342 DOI: 10.1152/Ajpcell.00433.2010 |
0.339 |
|
| 2011 |
Dai XQ, Plummer G, Casimir M, Kang Y, Hajmrle C, Gaisano HY, Manning Fox JE, MacDonald PE. SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans Diabetes. 60: 838-847. PMID 21266332 DOI: 10.2337/Db10-0440 |
0.486 |
|
| 2011 |
Binker MG, Binker-Cosen AA, Gaisano HY, de Cosen RH, Cosen-Binker LI. TGF-β1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-κB/IL-6/MMP-2. Biochemical and Biophysical Research Communications. 405: 140-5. PMID 21219858 DOI: 10.1016/J.Bbrc.2011.01.023 |
0.313 |
|
| 2011 |
Chen PC, Bruederle CE, Gaisano HY, Shyng SL. Syntaxin 1A regulates surface expression of beta-cell ATP-sensitive potassium channels. American Journal of Physiology. Cell Physiology. 300: C506-16. PMID 21209369 DOI: 10.1152/Ajpcell.00429.2010 |
0.387 |
|
| 2011 |
Kang Y, Zhang Y, Liang T, Leung YM, Ng B, Xie H, Chang N, Chan J, Shyng SL, Tsushima RG, Gaisano HY. ATP modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic beta-cell KATP channels. The Journal of Biological Chemistry. 286: 5876-83. PMID 21173146 DOI: 10.1074/Jbc.M109.089607 |
0.348 |
|
| 2011 |
Chao CC, Mihic A, Tsushima RG, Gaisano HY. SNARE protein regulation of cardiac potassium channels and atrial natriuretic factor secretion. Journal of Molecular and Cellular Cardiology. 50: 401-7. PMID 21129378 DOI: 10.1016/J.Yjmcc.2010.11.018 |
0.338 |
|
| 2011 |
Huang YC, Rupnik M, Gaisano HY. Unperturbed islet α-cell function examined in mouse pancreas tissue slices. The Journal of Physiology. 589: 395-408. PMID 21078586 DOI: 10.1113/Jphysiol.2010.200345 |
0.727 |
|
| 2010 |
Choi D, Schroer SA, Lu SY, Wang L, Wu X, Liu Y, Zhang Y, Gaisano HY, Wagner KU, Wu H, Retnakaran R, Woo M. Erythropoietin protects against diabetes through direct effects on pancreatic beta cells. The Journal of Experimental Medicine. 207: 2831-42. PMID 21149549 DOI: 10.1084/Jem.20100665 |
0.375 |
|
| 2010 |
Wang L, Liu Y, Yan Lu S, Nguyen KT, Schroer SA, Suzuki A, Mak TW, Gaisano H, Woo M. Deletion of Pten in pancreatic ß-cells protects against deficient ß-cell mass and function in mouse models of type 2 diabetes. Diabetes. 59: 3117-26. PMID 20852026 DOI: 10.2337/Db09-1805 |
0.413 |
|
| 2010 |
Columbus J, Chiang Y, Shao W, Zhang N, Wang D, Gaisano HY, Wang Q, Irwin DM, Jin T. Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas. The Journal of Endocrinology. 207: 77-86. PMID 20675304 DOI: 10.1677/Joe-10-0044 |
0.422 |
|
| 2010 |
Wijesekara N, Dai FF, Hardy AB, Giglou PR, Bhattacharjee A, Koshkin V, Chimienti F, Gaisano HY, Rutter GA, Wheeler MB. Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion. Diabetologia. 53: 1656-68. PMID 20424817 DOI: 10.1007/S00125-010-1733-9 |
0.446 |
|
| 2009 |
Han L, Jiang T, Han GA, Malintan NT, Xie L, Wang L, Tse FW, Gaisano HY, Collins BM, Meunier FA, Sugita S. Rescue of Munc18-1 and -2 double knockdown reveals the essential functions of interaction between Munc18 and closed syntaxin in PC12 cells. Molecular Biology of the Cell. 20: 4962-75. PMID 19812250 DOI: 10.1091/Mbc.E09-08-0712 |
0.327 |
|
| 2009 |
Choi D, Radziszewska A, Schroer SA, Liadis N, Liu Y, Zhang Y, Lam PP, Sheu L, Hao Z, Gaisano HY, Woo M. Deletion of Fas in the pancreatic beta-cells leads to enhanced insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 297: E1304-12. PMID 19755672 DOI: 10.1152/Ajpendo.00217.2009 |
0.448 |
|
| 2009 |
Hardy AB, Fox JE, Giglou PR, Wijesekara N, Bhattacharjee A, Sultan S, Gyulkhandanyan AV, Gaisano HY, MacDonald PE, Wheeler MB. Characterization of Erg K+ channels in alpha- and beta-cells of mouse and human islets. The Journal of Biological Chemistry. 284: 30441-52. PMID 19690348 DOI: 10.1074/Jbc.M109.040659 |
0.471 |
|
| 2009 |
Zhang Y, Liu Y, Qu J, Hardy A, Zhang N, Diao J, Strijbos PJ, Tsushima R, Robinson RB, Gaisano HY, Wang Q, Wheeler MB. Functional characterization of hyperpolarization-activated cyclic nucleotide-gated channels in rat pancreatic beta cells. The Journal of Endocrinology. 203: 45-53. PMID 19654142 DOI: 10.1677/Joe-09-0068 |
0.467 |
|
| 2009 |
Wang P, Wang Q, Sun J, Wu J, Li H, Zhang N, Huang Y, Su B, Li RK, Liu L, Zhang Y, Elsholtz HP, Hu J, Gaisano HY, Jin T. POU homeodomain protein Oct-1 functions as a sensor for cyclic AMP. The Journal of Biological Chemistry. 284: 26456-65. PMID 19617623 DOI: 10.1074/Jbc.M109.030668 |
0.688 |
|
| 2009 |
Vikman J, Svensson H, Huang YC, Kang Y, Andersson SA, Gaisano HY, Eliasson L. Truncation of SNAP-25 reduces the stimulatory action of cAMP on rapid exocytosis in insulin-secreting cells. American Journal of Physiology. Endocrinology and Metabolism. 297: E452-61. PMID 19509185 DOI: 10.1152/Ajpendo.90585.2008 |
0.745 |
|
| 2009 |
Zhang Y, Kang YH, Chang N, Lam PP, Liu Y, Olkkonen VM, Gaisano HY. Cab45b, a Munc18b-interacting partner, regulates exocytosis in pancreatic beta-cells. The Journal of Biological Chemistry. 284: 20840-7. PMID 19487699 DOI: 10.1074/Jbc.M109.017467 |
0.43 |
|
| 2009 |
Gaisano HY, Gorelick FS. New insights into the mechanisms of pancreatitis. Gastroenterology. 136: 2040-4. PMID 19379751 DOI: 10.1053/J.Gastro.2009.04.023 |
0.38 |
|
| 2009 |
Masson E, Koren S, Razik F, Goldberg H, Kwan EP, Sheu L, Gaisano HY, Fantus IG. High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice. American Journal of Physiology. Endocrinology and Metabolism. 296: E1251-61. PMID 19223654 DOI: 10.1152/Ajpendo.90619.2008 |
0.463 |
|
| 2009 |
Kwan EP, Gaisano HY. Rescuing the subprime meltdown in insulin exocytosis in diabetes. Annals of the New York Academy of Sciences. 1152: 154-64. PMID 19161386 DOI: 10.1111/J.1749-6632.2008.03990.X |
0.481 |
|
| 2009 |
Islam D, Zhang N, Wang P, Li H, Brubaker PL, Gaisano HY, Wang Q, Jin T. Epac is involved in cAMP-stimulated proglucagon expression and hormone production but not hormone secretion in pancreatic alpha- and intestinal L-cell lines. American Journal of Physiology. Endocrinology and Metabolism. 296: E174-81. PMID 18854429 DOI: 10.1152/Ajpendo.90419.2008 |
0.418 |
|
| 2009 |
Mihic A, Gao X, Shrier A, Gaisano H, Tsushima R. Binding of Syntaxin 1A to the C-terminus of hERG Channels Affects Channel Trafficking and Inactivation Biophysical Journal. 96: 175a. DOI: 10.1016/J.Bpj.2008.12.811 |
0.304 |
|
| 2008 |
Zhang Y, Zhang N, Gyulkhandanyan AV, Xu E, Gaisano HY, Wheeler MB, Wang Q. Presence of functional hyperpolarisation-activated cyclic nucleotide-gated channels in clonal alpha cell lines and rat islet alpha cells. Diabetologia. 51: 2290-8. PMID 18850083 DOI: 10.1007/S00125-008-1166-X |
0.368 |
|
| 2008 |
Ng B, Kang Y, Xie H, Sun H, Gaisano HY. Syntaxin-1A inhibition of P-1075, cromakalim, and diazoxide actions on mouse cardiac ATP-sensitive potassium channel. Cardiovascular Research. 80: 365-74. PMID 18703534 DOI: 10.1093/Cvr/Cvn210 |
0.335 |
|
| 2008 |
Xia F, Xie L, Mihic A, Gao X, Chen Y, Gaisano HY, Tsushima RG. Inhibition of cholesterol biosynthesis impairs insulin secretion and voltage-gated calcium channel function in pancreatic beta-cells. Endocrinology. 149: 5136-45. PMID 18599549 DOI: 10.1210/En.2008-0161 |
0.502 |
|
| 2008 |
Binker MG, Binker-Cosen AA, Gaisano HY, Cosen-Binker LI. Inhibition of Rac1 decreases the severity of pancreatitis and pancreatitis-associated lung injury in mice. Experimental Physiology. 93: 1091-103. PMID 18567599 DOI: 10.1113/Expphysiol.2008.043141 |
0.363 |
|
| 2008 |
Cosen-Binker LI, Binker MG, Wang CC, Hong W, Gaisano HY. VAMP8 is the v-SNARE that mediates basolateral exocytosis in a mouse model of alcoholic pancreatitis. The Journal of Clinical Investigation. 118: 2535-51. PMID 18535671 DOI: 10.1172/Jci34672 |
0.373 |
|
| 2008 |
Gaisano HY, Leung YM. Pancreatic islet alpha cell commands itself: secrete more glucagon! Cell Metabolism. 7: 474-5. PMID 18522828 DOI: 10.1016/J.Cmet.2008.05.003 |
0.384 |
|
| 2008 |
Lopez JA, Kwan EP, Xie L, He Y, James DE, Gaisano HY. The RalA GTPase is a central regulator of insulin exocytosis from pancreatic islet beta cells. The Journal of Biological Chemistry. 283: 17939-45. PMID 18426794 DOI: 10.1074/Jbc.M800321200 |
0.508 |
|
| 2008 |
Cosen-Binker LI, Morris GP, Vanner S, Gaisano HY. Munc18/SNARE proteins' regulation of exocytosis in guinea pig duodenal Brunner's gland acini. World Journal of Gastroenterology. 14: 2314-22. PMID 18416456 DOI: 10.3748/Wjg.14.2314 |
0.324 |
|
| 2008 |
Webster NJ, Searle GJ, Lam PP, Huang YC, Riedel MJ, Harb G, Gaisano HY, Holt A, Light PE. Elevation in intracellular long-chain acyl-coenzyme A esters lead to reduced beta-cell excitability via activation of adenosine 5'-triphosphate-sensitive potassium channels. Endocrinology. 149: 3679-87. PMID 18372336 DOI: 10.1210/En.2007-1138 |
0.735 |
|
| 2008 |
He Y, Elias CL, Huang YC, Gao X, Leung YM, Kang Y, Xie H, Chaddock JA, Tsushima RG, Gaisano HY. Botulinum neurotoxin A and neurotoxin E cleavage products of synaptosome-associated protein of 25 kd exhibit distinct actions on pancreatic islet beta-cell Kv2.1 channel gating. Pancreas. 36: 10-7. PMID 18192874 DOI: 10.1097/Mpa.0B013E31812Eee28 |
0.724 |
|
| 2008 |
Arunachalam L, Han L, Tassew NG, He Y, Wang L, Xie L, Fujita Y, Kwan E, Davletov B, Monnier PP, Gaisano HY, Sugita S. Munc18-1 is critical for plasma membrane localization of syntaxin1 but not of SNAP-25 in PC12 cells. Molecular Biology of the Cell. 19: 722-34. PMID 18077557 DOI: 10.1091/Mbc.E07-07-0662 |
0.354 |
|
| 2007 |
Kwan EP, Gaisano HY. New insights into the molecular mechanisms of priming of insulin exocytosis. Diabetes, Obesity & Metabolism. 9: 99-108. PMID 17919184 DOI: 10.1111/J.1463-1326.2007.00788.X |
0.49 |
|
| 2007 |
Kwan EP, Gao X, Leung YM, Gaisano HY. Activation of exchange protein directly activated by cyclic adenosine monophosphate and protein kinase A regulate common and distinct steps in promoting plasma membrane exocytic and granule-to-granule fusions in rat islet beta cells. Pancreas. 35: e45-54. PMID 17895835 DOI: 10.1097/Mpa.0B013E318073D1C9 |
0.442 |
|
| 2007 |
Leung YM, Kwan EP, Ng B, Kang Y, Gaisano HY. SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins. Endocrine Reviews. 28: 653-63. PMID 17878408 DOI: 10.1210/Er.2007-0010 |
0.445 |
|
| 2007 |
Min L, Leung YM, Tomas A, Watson RT, Gaisano HY, Halban PA, Pessin JE, Hou JC. Dynamin is functionally coupled to insulin granule exocytosis. The Journal of Biological Chemistry. 282: 33530-6. PMID 17848579 DOI: 10.1074/Jbc.M703402200 |
0.484 |
|
| 2007 |
Yamakawa T, Saith S, Li Y, Gao X, Gaisano HY, Tsushima RG. Interaction of syntaxin 1A with the N-terminus of Kv4.2 modulates channel surface expression and gating. Biochemistry. 46: 10942-9. PMID 17725325 DOI: 10.1021/Bi7006806 |
0.313 |
|
| 2007 |
Kwan EP, Xie L, Sheu L, Ohtsuka T, Gaisano HY. Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells. Diabetes. 56: 2579-88. PMID 17639022 DOI: 10.2337/Db06-1207 |
0.462 |
|
| 2007 |
Liadis N, Salmena L, Kwan E, Tajmir P, Schroer SA, Radziszewska A, Li X, Sheu L, Eweida M, Xu S, Gaisano HY, Hakem R, Woo M. Distinct in vivo roles of caspase-8 in beta-cells in physiological and diabetes models. Diabetes. 56: 2302-11. PMID 17563067 DOI: 10.2337/Db06-1771 |
0.432 |
|
| 2007 |
Fujita Y, Xu A, Xie L, Arunachalam L, Chou TC, Jiang T, Chiew SK, Kourtesis J, Wang L, Gaisano HY, Sugita S. Ca2+-dependent activator protein for secretion 1 is critical for constitutive and regulated exocytosis but not for loading of transmitters into dense core vesicles. The Journal of Biological Chemistry. 282: 21392-403. PMID 17540763 DOI: 10.1074/Jbc.M703699200 |
0.398 |
|
| 2007 |
Ng B, Kang Y, Elias CL, He Y, Xie H, Hansen JB, Wahl P, Gaisano HY. The actions of a novel potent islet beta-cell specific ATP-sensitive K+ channel opener can be modulated by syntaxin-1A acting on sulfonylurea receptor 1. Diabetes. 56: 2124-34. PMID 17496234 DOI: 10.2337/Db07-0030 |
0.38 |
|
| 2007 |
Lam PP, Cosen Binker LI, Lugea A, Pandol SJ, Gaisano HY. Alcohol redirects CCK-mediated apical exocytosis to the acinar basolateral membrane in alcoholic pancreatitis. Traffic (Copenhagen, Denmark). 8: 605-17. PMID 17451559 DOI: 10.1111/J.1600-0854.2007.00557.X |
0.3 |
|
| 2007 |
Lam PP, Hyvärinen K, Kauppi M, Cosen-Binker L, Laitinen S, Keränen S, Gaisano HY, Olkkonen VM. A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini. Molecular Biology of the Cell. 18: 2473-80. PMID 17442889 DOI: 10.1091/Mbc.E06-10-0950 |
0.334 |
|
| 2007 |
Ostenson CG, Chen J, Sheu L, Gaisano HY. Effects of palmitate on insulin secretion and exocytotic proteins in islets of diabetic Goto-Kakizaki rats. Pancreas. 34: 359-63. PMID 17414060 DOI: 10.1097/Mpa.0B013E3180304825 |
0.478 |
|
| 2007 |
Cosen-Binker LI, Lam PP, Binker MG, Reeve J, Pandol S, Gaisano HY. Alcohol/cholecystokinin-evoked pancreatic acinar basolateral exocytosis is mediated by protein kinase C alpha phosphorylation of Munc18c. The Journal of Biological Chemistry. 282: 13047-58. PMID 17324928 DOI: 10.1074/Jbc.M611132200 |
0.333 |
|
| 2007 |
Xia F, Leung YM, Gaisano G, Gao X, Chen Y, Fox JE, Bhattacharjee A, Wheeler MB, Gaisano HY, Tsushima RG. Targeting of voltage-gated K+ and Ca2+ channels and soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins to cholesterol-rich lipid rafts in pancreatic alpha-cells: effects on glucagon stimulus-secretion coupling. Endocrinology. 148: 2157-67. PMID 17303668 DOI: 10.1210/En.2006-1296 |
0.384 |
|
| 2007 |
Cosen-Binker LI, Gaisano HY. Recent insights into the cellular mechanisms of acute pancreatitis. Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 21: 19-24. PMID 17225878 DOI: 10.1155/2007/930424 |
0.305 |
|
| 2007 |
Cosen-Binker L, Binker M, Wang C, Hong W, Gaisano H. VAMP-8 IS THE V-SNARE MEDIATING BASOLATERAL EXOCYTOSIS IN ALCHOLIC PANCREATITIS. Pancreas. 35: 397. DOI: 10.1097/01.Mpa.0000297683.23321.2D |
0.31 |
|
| 2006 |
Wolf-Goldberg T, Michaelevski I, Sheu L, Gaisano HY, Chikvashvili D, Lotan I. Target soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNARES) differently regulate activation and inactivation gating of Kv2.2 and Kv2.1: Implications on pancreatic islet cell Kv channels Molecular Pharmacology. 70: 818-828. PMID 16754785 DOI: 10.1124/Mol.105.021717 |
0.408 |
|
| 2006 |
Dai FF, Zhang Y, Kang Y, Wang Q, Gaisano HY, Braunewell KH, Chan CB, Wheeler MB. The neuronal Ca2+ sensor protein visinin-like protein-1 is expressed in pancreatic islets and regulates insulin secretion. The Journal of Biological Chemistry. 281: 21942-53. PMID 16731532 DOI: 10.1074/Jbc.M512924200 |
0.5 |
|
| 2006 |
Leung YM, Ahmed I, Sheu L, Tsushima RG, Diamant NE, Gaisano HY. Two populations of pancreatic islet alpha-cells displaying distinct Ca2+ channel properties. Biochemical and Biophysical Research Communications. 345: 340-4. PMID 16678791 DOI: 10.1016/J.Bbrc.2006.04.066 |
0.376 |
|
| 2006 |
Kang Y, Ng B, Leung YM, He Y, Xie H, Lodwick D, Norman RI, Tinker A, Tsushima RG, Gaisano HY. Syntaxin-1A actions on sulfonylurea receptor 2A can block acidic pH-induced cardiac K(ATP) channel activation. The Journal of Biological Chemistry. 281: 19019-28. PMID 16672225 DOI: 10.1074/Jbc.M513160200 |
0.3 |
|
| 2006 |
Lotfi S, Li Z, Sun J, Zuo Y, Lam PP, Kang Y, Rahimi M, Islam D, Wang P, Gaisano HY, Jin T. Role of the exchange protein directly activated by cyclic adenosine 5'-monophosphate (Epac) pathway in regulating proglucagon gene expression in intestinal endocrine L cells. Endocrinology. 147: 3727-36. PMID 16644915 DOI: 10.1210/En.2006-0056 |
0.336 |
|
| 2006 |
Kwan EP, Xie L, Sheu L, Nolan CJ, Prentki M, Betz A, Brose N, Gaisano HY. Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance. Diabetes. 55: 1421-9. PMID 16644700 DOI: 10.2337/Db05-1263 |
0.479 |
|
| 2006 |
He Y, Kang Y, Leung YM, Xia F, Gao X, Xie H, Gaisano HY, Tsushima RG. Modulation of Kv2.1 channel gating and TEA sensitivity by distinct domains of SNAP-25. The Biochemical Journal. 396: 363-9. PMID 16478442 DOI: 10.1042/Bj20051478 |
0.327 |
|
| 2006 |
Leung YM, Ahmed I, Sheu L, Gao X, Hara M, Tsushima RG, Diamant NE, Gaisano HY. Insulin regulates islet alpha-cell function by reducing KATP channel sensitivity to adenosine 5'-triphosphate inhibition. Endocrinology. 147: 2155-62. PMID 16455778 DOI: 10.1210/En.2005-1249 |
0.454 |
|
| 2006 |
Ostenson CG, Gaisano H, Sheu L, Tibell A, Bartfai T. Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients. Diabetes. 55: 435-40. PMID 16443778 DOI: 10.2337/Diabetes.55.02.06.Db04-1575 |
0.424 |
|
| 2006 |
Zhang N, Kumar M, Xu G, Ju W, Yoon T, Xu E, Huang X, Gaisano H, Peng C, Wang Q. Activin receptor-like kinase 7 induces apoptosis of pancreatic beta cells and beta cell lines. Diabetologia. 49: 506-518. PMID 16440210 DOI: 10.1007/S00125-005-0095-1 |
0.366 |
|
| 2006 |
Cosen-Binker L, Lam P, Gaisano H. LOW-DOSE ALCOHOL REDIRECTS POSTPRANDIAL CHOLINERGIC-STIMULATED APICAL EXOCYTOSIS TO THE BASOLATERAL MEMBRANE IN PANCREATIC ACINAR CELLS, THE SUSCEPTIBILITY MECHANISM OF ALCOHOLIC PANCREATITIS Pancreas. 33: 453-454. DOI: 10.1097/00006676-200611000-00062 |
0.315 |
|
| 2005 |
Lam PP, Leung YM, Sheu L, Ellis J, Tsushima RG, Osborne LR, Gaisano HY. Transgenic mouse overexpressing syntaxin-1A as a diabetes model. Diabetes. 54: 2744-54. PMID 16123365 DOI: 10.2337/Diabetes.54.9.2744 |
0.454 |
|
| 2005 |
Kwan EP, Gaisano HY. Glucagon-like peptide 1 regulates sequential and compound exocytosis in pancreatic islet beta-cells. Diabetes. 54: 2734-43. PMID 16123364 DOI: 10.2337/Diabetes.54.9.2734 |
0.438 |
|
| 2005 |
Leung YM, Ahmed I, Sheu L, Tsushima RG, Diamant NE, Hara M, Gaisano HY. Electrophysiological characterization of pancreatic islet cells in the mouse insulin promoter-green fluorescent protein mouse. Endocrinology. 146: 4766-75. PMID 16109783 DOI: 10.1210/En.2005-0803 |
0.431 |
|
| 2005 |
Liadis N, Murakami K, Eweida M, Elford AR, Sheu L, Gaisano HY, Hakem R, Ohashi PS, Woo M. Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus. Molecular and Cellular Biology. 25: 3620-9. PMID 15831467 DOI: 10.1128/Mcb.25.9.3620-3629.2005 |
0.371 |
|
| 2005 |
Muinuddin A, Naqvi K, Sheu L, Gaisano HY, Diamant NE. Regional differences in cholinergic regulation of potassium current in feline esophageal circular smooth muscle. American Journal of Physiology. Gastrointestinal and Liver Physiology. 288: G1233-40. PMID 15691872 DOI: 10.1152/Ajpgi.00310.2004 |
0.326 |
|
| 2005 |
Leung YM, Kang Y, Xia F, Sheu L, Gao X, Xie H, Tsushima RG, Gaisano HY. Open form of syntaxin-1A is a more potent inhibitor than wild-type syntaxin-1A of Kv2.1 channels. The Biochemical Journal. 387: 195-202. PMID 15518587 DOI: 10.1042/Bj20041625 |
0.334 |
|
| 2004 |
Cui N, Kang Y, He Y, Leung YM, Xie H, Pasyk EA, Gao X, Sheu L, Hansen JB, Wahl P, Tsushima RG, Gaisano HY. H3 domain of syntaxin 1A inhibits KATP channels by its actions on the sulfonylurea receptor 1 nucleotide-binding folds-1 and -2. The Journal of Biological Chemistry. 279: 53259-65. PMID 15485808 DOI: 10.1074/Jbc.M410171200 |
0.375 |
|
| 2004 |
Kang Y, Leung YM, Manning-Fox JE, Xia F, Xie H, Sheu L, Tsushima RG, Light PE, Gaisano HY. Syntaxin-1A inhibits cardiac KATP channels by its actions on nucleotide binding folds 1 and 2 of sulfonylurea receptor 2A. The Journal of Biological Chemistry. 279: 47125-31. PMID 15339904 DOI: 10.1074/Jbc.M404954200 |
0.399 |
|
| 2004 |
Gaisano HY, Sheu L, Whitcomb D. Alcoholic chronic pancreatitis involves displacement of Munc18c from the pancreatic acinar basal membrane surface. Pancreas. 28: 395-400. PMID 15097857 DOI: 10.1097/00006676-200405000-00008 |
0.36 |
|
| 2004 |
Xia F, Gao X, Kwan E, Lam PP, Chan L, Sy K, Sheu L, Wheeler MB, Gaisano HY, Tsushima RG. Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis. The Journal of Biological Chemistry. 279: 24685-91. PMID 15073181 DOI: 10.1074/Jbc.M314314200 |
0.423 |
|
| 2003 |
Pasyk EA, Kang Y, Huang X, Cui N, Sheu L, Gaisano HY. Syntaxin-1A binds the nucleotide-binding folds of sulphonylurea receptor 1 to regulate the KATP channel. The Journal of Biological Chemistry. 279: 4234-40. PMID 14645230 DOI: 10.1074/Jbc.M309667200 |
0.329 |
|
| 2003 |
Sheu L, Pasyk EA, Ji J, Huang X, Gao X, Varoqueaux F, Brose N, Gaisano HY. Regulation of insulin exocytosis by Munc13-1. The Journal of Biological Chemistry. 278: 27556-63. PMID 12871971 DOI: 10.1074/Jbc.M303203200 |
0.503 |
|
| 2003 |
Ji J, Muinuddin A, Kang Y, Diamant NE, Gaisano HY. SNAP-25 inhibits L-type Ca2+ channels in feline esophagus smooth muscle cells Biochemical and Biophysical Research Communications. 306: 298-302. PMID 12788104 DOI: 10.1016/S0006-291X(03)00968-9 |
0.35 |
|
| 2003 |
Leung YM, Kang Y, Gao X, Xia F, Xie H, Sheu L, Tsuk S, Lotan I, Tsushima RG, Gaisano HY. Syntaxin 1A binds to the cytoplasmic C terminus of Kv2.1 to regulate channel gating and trafficking. The Journal of Biological Chemistry. 278: 17532-8. PMID 12621036 DOI: 10.1074/Jbc.M213088200 |
0.383 |
|
| 2003 |
Huang X, Sheu L, Kang Y, Eto Y, Kojima I, Gaisano HY. Effects of selective endocrine or exocrine induction of AR42J on SNARE and Munc18 protein expression. Pancreas. 25: e56-63. PMID 12409842 DOI: 10.1097/00006676-200211000-00022 |
0.446 |
|
| 2002 |
MacDonald PE, Wang G, Tsuk S, Dodo C, Kang Y, Tang L, Wheeler MB, Cattral MS, Lakey JR, Salapatek AM, Lotan I, Gaisano HY. Synaptosome-associated protein of 25 kilodaltons modulates Kv2.1 voltage-dependent K(+) channels in neuroendocrine islet beta-cells through an interaction with the channel N terminus. Molecular Endocrinology (Baltimore, Md.). 16: 2452-61. PMID 12403834 DOI: 10.1210/Me.2002-0058 |
0.416 |
|
| 2002 |
Gaisano HY, Ostenson CG, Sheu L, Wheeler MB, Efendic S. Abnormal expression of pancreatic islet exocytotic soluble N-ethylmaleimide-sensitive factor attachment protein receptors in Goto-Kakizaki rats is partially restored by phlorizin treatment and accentuated by high glucose treatment. Endocrinology. 143: 4218-26. PMID 12399415 DOI: 10.1210/En.2002-220237 |
0.436 |
|
| 2002 |
Ji J, Lau H, Sheu L, Diamant NE, Gaisano HY. Distinct regional expression of SNARE proteins in the feline oesophagus Neurogastroenterology and Motility. 14: 383-394. PMID 12213106 DOI: 10.1046/J.1365-2982.2002.00343.X |
0.336 |
|
| 2002 |
Ji J, Yang SN, Huang X, Li X, Sheu L, Diamant N, Berggren PO, Gaisano HY. Modulation of L-type Ca2+ channels by distinct domains within SNAP-25 Diabetes. 51: 1425-1436. PMID 11978639 DOI: 10.2337/Diabetes.51.5.1425 |
0.415 |
|
| 2002 |
Leung YM, Sheu L, Kwan E, Wang G, Tsushima R, Gaisano H. Visualization of sequential exocytosis in rat pancreatic islet beta cells. Biochemical and Biophysical Research Communications. 292: 980-6. PMID 11944911 DOI: 10.1006/Bbrc.2002.6712 |
0.469 |
|
| 2002 |
Kang Y, Huang X, Pasyk EA, Ji J, Holz GG, Wheeler MB, Tsushima RG, Gaisano HY. Syntaxin-3 and syntaxin-1A inhibit L-type calcium channel activity, insulin biosynthesis and exocytosis in beta-cell lines. Diabetologia. 45: 231-41. PMID 11935155 DOI: 10.1007/S00125-001-0718-0 |
0.466 |
|
| 2002 |
Ji J, Tsuk S, Salapatek AM, Huang X, Chikvashvili D, Pasyk EA, Kang Y, Sheu L, Tsushima R, Diamant N, Trimble WS, Lotan I, Gaisano HY. The 25-kDa synaptosome-associated protein (SNAP-25) binds and inhibits delayed rectifier potassium channels in secretory cells. The Journal of Biological Chemistry. 277: 20195-204. PMID 11925439 DOI: 10.1074/Jbc.M201034200 |
0.375 |
|
| 2002 |
Ji J, Salapatek AMF, Lau H, Wang G, Gaisano HY, Diamant NE. SNAP-25, a SNARE protein, inhibits two types of K+ channels in esophageal smooth muscle Gastroenterology. 122: 994-1006. PMID 11910352 DOI: 10.1053/Gast.2002.32412 |
0.35 |
|
| 2001 |
Gaisano HY, Lutz MP, Leser J, Sheu L, Lynch G, Tang L, Tamori Y, Trimble WS, Salapatek AM. Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane. The Journal of Clinical Investigation. 108: 1597-611. PMID 11733555 DOI: 10.1172/Jci9110 |
0.381 |
|
| 2001 |
Huang X, Kang YH, Pasyk EA, Sheu L, Wheeler MB, Trimble WS, Salapatek A, Gaisano HY. Ca2+ influx and cAMP elevation overcame botulinum toxin A but not tetanus toxin inhibition of insulin exocytosis American Journal of Physiology - Cell Physiology. 281. PMID 11502551 DOI: 10.1152/Ajpcell.2001.281.3.C740 |
0.449 |
|
| 2001 |
Huang X, Sheu L, Tamori Y, Trimble WS, Gaisano HY. Cholecystokinin-regulated exocytosis in rat pancreatic acinar cells is inhibited by a C-terminus truncated mutant of SNAP-23. Pancreas. 23: 125-33. PMID 11484914 DOI: 10.1097/00006676-200108000-00002 |
0.391 |
|
| 2001 |
Macdonald PE, Ha XF, Wang J, Smukler SR, Sun AM, Gaisano HY, Salapatek AMF, Backx PH, Wheeler MB. Members of the Kv1 and Kv2 voltage-dependent K+ channel families regulate insulin secretion Molecular Endocrinology. 15: 1423-1435. PMID 11463864 DOI: 10.1210/Mend.15.8.0685 |
0.477 |
|
| 2000 |
Gaisano HY. A hypothesis: SNARE-ing the mechanisms of regulated exocytosis and pathologic membrane fusions in the pancreatic acinar cell. Pancreas. 20: 217-26. PMID 10766446 DOI: 10.1097/00006676-200004000-00001 |
0.365 |
|
| 2000 |
Gaisano HY, Huang X, Trimble WS, Sheu L. The role of SNAP23 in CCK-evoked enzyme secretion in pancreatic acinar cells: Functional redundancy between SNAP25 and SNAP23 Gastroenterology. 118: A156. DOI: 10.1016/S0016-5085(00)82700-6 |
0.371 |
|
| 1999 |
Salapatek AM, MacDonald PE, Gaisano HY, Wheeler MB. Mutations to the third cytoplasmic domain of the glucagon-like peptide 1 (GLP-1) receptor can functionally uncouple GLP-1-stimulated insulin secretion in HIT-T15 cells. Molecular Endocrinology (Baltimore, Md.). 13: 1305-17. PMID 10446905 DOI: 10.1210/Mend.13.8.0321 |
0.466 |
|
| 1999 |
Gaisano HY, Huang X, Sheu L, Ghai M, Newgard CB, Trinh KY, Trimble WS. Snare protein expression and adenoviral transfection of amphicrine AR42J Biochemical and Biophysical Research Communications. 260: 781-784. PMID 10403842 DOI: 10.1006/Bbrc.1999.0987 |
0.351 |
|
| 1999 |
Chan CB, MacPhail RM, Sheu L, Wheeler MB, Gaisano HY. β-Cell hypertrophy in fa/fa rats is associated with basal glucose hypersensitivity and reduced SNARE protein expression Diabetes. 48: 997-1005. PMID 10331403 DOI: 10.2337/Diabetes.48.5.997 |
0.478 |
|
| 1998 |
Huang X, Wheeler MB, Kang YH, Sheu L, Lukacs GL, Trimble WS, Gaisano HY. Truncated SNAP-25 (1-197), like botulinum neurotoxin A, can inhibit insulin secretion from HIT-T15 insulinoma cells Molecular Endocrinology. 12: 1060-1070. PMID 9658409 DOI: 10.1210/Mend.12.7.0130 |
0.472 |
|
| 1998 |
Gaisano H, Leser J, Sheu L, Tamori Y, Trimble W, Lutz M. SNARE proteins (Munc 18c/syntaxin-4/SNAP-23/VAMP-2) mediate basolateral plasma membrane exocytosis during experimental acute pancreatitis Gastroenterology. 114: A460-A461. DOI: 10.1016/S0016-5085(98)81862-3 |
0.318 |
|
| 1997 |
Lutz MP, Piiper A, Gaisano HY, Stryjek-Kaminska D, Zeuzem S, Adler G. Protein tyrosine phosphorylation in pancreatic acini: differential effects of VIP and CCK. American Journal of Physiology. Gastrointestinal and Liver Physiology. 273: G1226-G1232. PMID 29585255 DOI: 10.1152/Ajpgi.1997.273.6.G1226 |
0.32 |
|
| 1997 |
Gaisano HY, Sheu L, Wong PPC, Klip A, Trimble WS. SNAP-23 is located in the basolateral plasma membrane of rat: Pancreatic acinar cells Febs Letters. 414: 298-302. PMID 9315706 DOI: 10.1016/S0014-5793(97)01013-2 |
0.334 |
|
| 1996 |
Gaisano HY, Ghai M, Malkus PN, Sheu L, Bouquillon A, Bennett MK, Trimble WS. Distinct cellular locations of the syntaxin family of proteins in rat pancreatic acinar cells. Molecular Biology of the Cell. 7: 2019-27. PMID 8970162 DOI: 10.1091/Mbc.7.12.2019 |
0.355 |
|
| 1996 |
Gaisano HY, Sheu L, Grondin G, Ghai M, Bouquillon A, Lowe A, Beaudoin A, Trimble WS. The vesicle-associated membrane protein family of proteins in rat pancreatic and parotid acinar cells Gastroenterology. 111: 1661-1669. PMID 8942747 DOI: 10.1016/S0016-5085(96)70030-6 |
0.38 |
|
| 1996 |
Wheeler MB, Sheu L, Ghai M, Bouquillon A, Grondin G, Weller U, Beaudoin AR, Bennett MK, Trimble WS, Gaisano HY. Characterization of SNARE protein expression in beta cell lines and pancreatic islets. Endocrinology. 137: 1340-8. PMID 8625909 DOI: 10.1210/Endo.137.4.8625909 |
0.455 |
|
| 1994 |
Gaisano HY, Wong D, Sheu L, Foskett JK. Calcium release by cholecystokinin analogue OPE is IP3 dependent in single rat pancreatic acinar cells American Journal of Physiology - Cell Physiology. 267. PMID 8048482 DOI: 10.1152/Ajpcell.1994.267.1.C220 |
0.309 |
|
| 1994 |
Gaisano HY, Miller LJ. Low concentrations of protein kinase c-activating agonists suppress cholecystokinin-ope-evoked ca2 mobilization in rat pancreatic acini Pancreas. 9: 450-453. PMID 7937693 DOI: 10.1097/00006676-199407000-00006 |
0.337 |
|
| 1992 |
Gaisano HY, Miller LJ. Complex role of protein kinase C in mediating the supramaximal inhibition of pancreatic secretion observed with cholecystokinin Biochemical and Biophysical Research Communications. 187: 498-506. PMID 1520340 DOI: 10.1016/S0006-291X(05)81522-0 |
0.328 |
|
| 1989 |
Gaisano HY, Klueppelberg UG, Pinon DI, Pfenning MA, Powers SP, Miller LJ. Novel tool for the study of cholecystokinin-stimulated pancreatic enzyme secretion. The Journal of Clinical Investigation. 83: 321-5. PMID 2910915 DOI: 10.1172/Jci113877 |
0.334 |
|
| 1989 |
Klueppelberg UG, Gaisano HY, Powers SP, Miller LJ. Use of a nitrotryptophan-containing peptide for photoaffinity labeling the pancreatic cholecystokinin receptor. Biochemistry. 28: 3463-8. PMID 2742849 DOI: 10.1021/Bi00434A047 |
0.315 |
|
| 1987 |
Pearson RK, Powers SP, Hadac EM, Gaisano H, Miller LJ. Establishment of a new short, protease-resistant, affinity labeling reagent for the cholecystokinin receptor. Biochemical and Biophysical Research Communications. 147: 346-53. PMID 2443134 DOI: 10.1016/S0006-291X(87)80128-6 |
0.33 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2014 |
Banks K, Qin T, Liang T, Wang AJ, Gaisano HY. Biliopancreatic route for effective viral transduction of pancreatic islets. Pancreas. 43: 240-4. PMID 24518502 DOI: 10.1097/Mpa.0000000000000096 |
0.3 |
|
| 2011 |
Chao C, Liang T, Kang Y, Lin X, Xie H, Feng ZP, Gaisano HY. Syntaxin-1A inhibits KATP channels by interacting with specific conserved motifs within sulfonylurea receptor 2A. Journal of Molecular and Cellular Cardiology. 51: 790-802. PMID 21884702 DOI: 10.1016/J.Yjmcc.2011.08.011 |
0.298 |
|
| 2006 |
Chai Y, Huang X, Cong B, Liu S, Chen K, Li G, Gaisano HY. Involvement of VAMP-2 in exocytosis of IL-1 beta in turbot (Scophthalmus maximus) leukocytes after Vibrio anguillarum infection. Biochemical and Biophysical Research Communications. 342: 509-13. PMID 16487935 DOI: 10.1016/J.Bbrc.2006.01.138 |
0.297 |
|
| 2007 |
Neshatian L, Leung YM, Kang Y, Gao X, Xie H, Tsushima RG, Gaisano HY, Diamant NE. Distinct modulation of Kv1.2 channel gating by wild type, but not open form, of syntaxin-1A. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G1233-42. PMID 17234891 DOI: 10.1152/Ajpgi.00473.2006 |
0.296 |
|
| 2007 |
Cosen-Binker LI, Lam PP, Binker MG, Gaisano HY. Alcohol-induced protein kinase Calpha phosphorylation of Munc18c in carbachol-stimulated acini causes basolateral exocytosis. Gastroenterology. 132: 1527-45. PMID 17408632 DOI: 10.1053/J.Gastro.2007.01.042 |
0.294 |
|
| 2020 |
Jiang J, Cai X, Pan Y, Du X, Zhu H, Yang X, Zheng D, Gaisano H, Wei T, He Y. Relationship of obesity to adipose tissue insulin resistance. Bmj Open Diabetes Research & Care. 8. PMID 32245824 DOI: 10.1136/Bmjdrc-2019-000741 |
0.29 |
|
| 2007 |
Ahmed I, Cosen-Binker LI, Leung YM, Gaisano HY, Diamant NE. Modulation of the K(v)4.3 channel by syntaxin 1A. Biochemical and Biophysical Research Communications. 358: 789-95. PMID 17506992 DOI: 10.1016/J.Bbrc.2007.04.182 |
0.287 |
|
| 2012 |
Dolai S, Liang T, Lam PP, Fernandez NA, Chidambaram S, Gaisano HY. Effects of ethanol metabolites on exocytosis of pancreatic acinar cells in rats. Gastroenterology. 143: 832-43.e1-7. PMID 22710192 DOI: 10.1053/J.Gastro.2012.06.011 |
0.286 |
|
| 2010 |
L'Heureux MC, Muinuddin A, Gaisano HY, Diamant NE. Nitric oxide activation of a potassium channel (BK(Ca)) in feline lower esophageal sphincter. World Journal of Gastroenterology. 16: 5852-60. PMID 21155007 DOI: 10.3748/Wjg.V16.I46.5852 |
0.286 |
|
| 1994 |
Gaisano HY, Miller LJ, Foskett JK. Suppression of Ca2+ oscillations induced by cholecystokinin (CCK) and its analog OPE in rat pancreatic acinar cells by low-level protein kinase C activation without transition of the CCK receptor from a high- to low-affinity state PflüGers Archiv European Journal of Physiology. 427: 455-462. PMID 7971144 DOI: 10.1007/Bf00374261 |
0.285 |
|
| 2013 |
Orabi A, Dolai S, Liang T, Husain S, Gaisano H. Performing functional assays from a pancreas slice to examine early features of acute pancreatitis Pancreatology. 13: e63-e64. DOI: 10.1016/J.Pan.2012.12.277 |
0.284 |
|
| 2022 |
Kang F, Gaisano HY. Imaging Insulin Granule Dynamics in Human Pancreatic β-Cells Using Total Internal Reflection Fluorescence (TIRF) Microscopy. Methods in Molecular Biology (Clifton, N.J.). 2473: 79-88. PMID 35819760 DOI: 10.1007/978-1-0716-2209-4_7 |
0.282 |
|
| 2017 |
Fu J, Dai X, Plummer G, Suzuki K, Jensen M, Greitzer-Antes D, Fox JEM, Gaisano HY, Newgard CB, Macdonald PE. Kv2.1 Clustering Contributes to Exocytosis Hotspots and Rescues Human β-Cell Dysfunction Canadian Journal of Diabetes. 41: S11-S12. DOI: 10.1016/J.Jcjd.2017.08.039 |
0.282 |
|
| 2013 |
Dolai S, Orabi AI, Javed TA, Liang T, Thurmond DC, Husain SZ, Gaisano HY. Sa1854 Munc18c Mediates Caerulein-Induced Pancreatitis and Basolateral SNARE Complex Assembly Gastroenterology. 144: S-321. DOI: 10.1016/S0016-5085(13)61164-6 |
0.282 |
|
| 2004 |
Muinuddin A, Ji J, Sheu L, Kang Y, Gaisano HY, Diamant NE. L-type Ca2+ channel expression along feline smooth muscle oesophagus Neurogastroenterology and Motility. 16: 325-334. PMID 15198655 DOI: 10.1111/J.1365-2982.2004.00523.X |
0.282 |
|
| 2007 |
Chen K, Huang X, Chai Y, Gaisano HY. Characterization of SNAP-25 Gene from Marine Teleostean, Lateolabrax japonicus Chinese Journal of Oceanology and Limnology. 25: 378-385. DOI: 10.1007/S00343-007-0378-0 |
0.281 |
|
| 2012 |
Dolai S, Liang T, Lam PP, Fernandez NA, Gaisano HY. 79 Distinct Actions of Ethanol Metabolites in Pathologic Rat Pancreatic Acinar Exocytosis Underlying Alcoholic Pancreatitis Gastroenterology. 142: S-19. DOI: 10.1016/S0016-5085(12)60074-2 |
0.279 |
|
| 2014 |
Xie L, Liang T, Kang Y, Lin X, Sobbi R, Xie H, Chao C, Backx P, Feng ZP, Shyng SL, Gaisano HY. Phosphatidylinositol 4,5-biphosphate (PIP2) modulates syntaxin-1A binding to sulfonylurea receptor 2A to regulate cardiac ATP-sensitive potassium (KATP) channels. Journal of Molecular and Cellular Cardiology. 75: 100-10. PMID 25073062 DOI: 10.1016/J.Yjmcc.2014.07.012 |
0.278 |
|
| 2010 |
Binker MG, Binker-Cosen AA, Richards D, Gaisano HY, de Cosen RH, Cosen-Binker LI. Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2. Biochemical and Biophysical Research Communications. 393: 371-6. PMID 20153729 DOI: 10.1016/J.Bbrc.2010.01.125 |
0.278 |
|
| 1992 |
Miller LJ, Hadac EM, Gates LK, Gaisano HY. Binding of a phenethyl ester analogue of cholecystokinin to the solubilized pancreatic cholecystokinin receptor: use in ligand-affinity chromatography. Biochemical and Biophysical Research Communications. 183: 396-404. PMID 1550549 DOI: 10.1016/0006-291X(92)90494-6 |
0.272 |
|
| 2023 |
Thompson PJ, Pipella J, Rutter GA, Gaisano HY, Santamaria P. Islet autoimmunity in human type 1 diabetes: initiation and progression from the perspective of the beta cell. Diabetologia. 66: 1971-1982. PMID 37488322 DOI: 10.1007/s00125-023-05970-z |
0.267 |
|
| 2020 |
Li W, Wang A, Jiang J, Liu G, Wang M, Li D, Wen J, Mu Y, Du X, Gaisano H, Dou J, He Y. Risk of chronic kidney disease defined by decreased estimated glomerular filtration rate in individuals with different prediabetic phenotypes: results from a prospective cohort study in China. Bmj Open Diabetes Research & Care. 8. PMID 32245825 DOI: 10.1136/Bmjdrc-2019-000955 |
0.263 |
|
| 2014 |
Dolai S, Orabi AI, Liang T, Javed TA, Lam PP, Rubin DC, Husain SZ, Gaisano HY. 794f Syntaxin 2 Deficiency Predisposes Mice to Pancreatitis by Enhancing Basolateral Exocytosis and Autophagy Gastroenterology. 146: S-138. DOI: 10.1016/S0016-5085(14)60488-1 |
0.262 |
|
| 1987 |
Gaisano HY, Reilly W, Go VL, Olivero D, Miller LJ. Large molecular forms of cholecystokinin circulating in humans. Pancreas. 1: 148-53. PMID 2437562 DOI: 10.1097/00006676-198603000-00007 |
0.261 |
|
| 2010 |
Binker MG, Binker-Cosen AA, Richards D, Gaisano HY, de Cosen RH, Cosen-Binker LI. Chronic stress sensitizes rats to pancreatitis induced by cerulein: role of TNF-α. World Journal of Gastroenterology. 16: 5565-81. PMID 21105189 DOI: 10.3748/Wjg.V16.I44.5565 |
0.26 |
|
| 2004 |
Muinuddin A, Kang Y, Gaisano HY, Diamant NE. Regional differences in L-type Ca2+ channel expression in feline lower esophageal sphincter. American Journal of Physiology. Gastrointestinal and Liver Physiology. 287: G772-81. PMID 15178551 DOI: 10.1152/Ajpgi.00102.2004 |
0.253 |
|
| 2004 |
Muinuddin A, Neshatian L, Gaisano HY, Diamant NE. Calcium source diversity in feline lower esophageal sphincter circular and sling muscle American Journal of Physiology - Gastrointestinal and Liver Physiology. 286. PMID 14563670 DOI: 10.1152/Ajpgi.00291.2003 |
0.253 |
|
| 2020 |
Dolai S, Takahashi T, Qin T, Liang T, Xie L, Kang F, Miao YF, Xie H, Kang Y, Manuel J, Winter E, Roche PA, Cattral MS, Gaisano HY. Pancreas-specific SNAP23 Depletion Prevents Pancreatitis by Attenuating Pathological Basolateral Exocytosis and Formation of Trypsin-activating Autolysosomes. Autophagy. PMID 33213278 DOI: 10.1080/15548627.2020.1852725 |
0.252 |
|
| 2013 |
Mendez M, Gaisano HY. Role of the SNARE protein SNAP23 on cAMP-stimulated renin release in mouse juxtaglomerular cells. American Journal of Physiology. Renal Physiology. 304: F498-504. PMID 23269646 DOI: 10.1152/ajprenal.00556.2012 |
0.241 |
|
| 2001 |
Gaisano HY, Tang L, Sheu L, Trimble WS. Visualization of CCK-evoked exocytic events in rat pancreatic acinar cells Gastroenterology. 120: A24. DOI: 10.1016/S0016-5085(08)80116-3 |
0.24 |
|
| 2007 |
Chen K, Huang X, Bao Z, Gaisano H. Characterization of VAMP-2 gene from marine teleostean, Lateolabrax japonicus. Science in China. Series C, Life Sciences. 49: 591-6. PMID 17312998 DOI: 10.1007/S11427-006-2035-9 |
0.239 |
|
| 2016 |
Pan Y, Wang Y, Li H, Gaisano HY, Wang Y, He Y. Association of Diabetes and Prognosis of Minor Stroke and Its Subtypes: A Prospective Observational Study. Plos One. 11: e0153178. PMID 27070309 DOI: 10.1371/Journal.Pone.0153178 |
0.232 |
|
| 2019 |
Jiang J, Cui J, Wang A, Mu Y, Yan Y, Liu F, Pan Y, Li D, Li W, Liu G, Gaisano HY, Dou J, He Y. Association Between Age at Natural Menopause and Risk of Type 2 Diabetes in Postmenopausal Obese and Non-Obese Females. The Journal of Clinical Endocrinology and Metabolism. PMID 30896740 DOI: 10.1210/Jc.2018-02310 |
0.23 |
|
| 1991 |
Kamath PS, Gaisano HY, Phillips SF, Miller LJ, Charboneau JW, Brown ML, Zinsmeister AR. Abnormal gallbladder motility in irritable bowel syndrome: evidence for target-organ defect. The American Journal of Physiology. 260: G815-9. PMID 2058671 DOI: 10.1152/Ajpgi.1991.260.6.G815 |
0.23 |
|
| 2006 |
L'Heureux MC, Muinuddin A, Gaisano HY, Diamant NE. Feline lower esophageal sphincter sling and circular muscles have different functional inhibitory neuronal responses. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G23-9. PMID 16166343 DOI: 10.1152/Ajpgi.00303.2005 |
0.228 |
|
| 2019 |
Menegaz D, Hagan DW, Almaça J, Cianciaruso C, Rodriguez-Diaz R, Molina J, Dolan RM, Becker MW, Schwalie PC, Nano R, Lebreton F, Kang C, Sah R, Gaisano HY, Berggren PO, et al. MECHANISM AND EFFECTS OF PULSATILE GABA SECRETION FROM CYTOSOLIC POOLS IN THE HUMAN BETA CELL. Nature Metabolism. 1: 1110-1126. PMID 32432213 DOI: 10.1038/s42255-019-0135-7 |
0.226 |
|
| 2023 |
Jiang J, Li Y, Li F, He Y, Song L, Wang K, You W, Xia Z, Zuo Y, Su X, Zhai Q, Zhang Y, Gaisano H, Zheng D. Post-Load Insulin Secretion Patterns are Associated with Glycemic Status and Diabetic Complications in Patients with Type 2 Diabetes Mellitus. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. PMID 36796421 DOI: 10.1055/a-2018-4299 |
0.219 |
|
| 2003 |
Michaelevski I, Chikvashvili D, Tsuk S, Singer-Lahat D, Kang Y, Linial M, Gaisano HY, Fili O, Lotan I. Direct interaction of target SNAREs with the Kv2.1 channel: Modal regulation of channel activation and inactivation gating Journal of Biological Chemistry. 278: 34320-34330. PMID 12807875 DOI: 10.1074/jbc.M304943200 |
0.216 |
|
| 2017 |
Jiang J, Cui J, Yang X, Wang A, Mu Y, Dong L, Wang S, Gaisano H, Dou J, He Y. Neck Circumference, a Novel Indicator for Hyperuricemia. Frontiers in Physiology. 8: 965. PMID 29238304 DOI: 10.3389/Fphys.2017.00965 |
0.212 |
|
| 2017 |
Xia L, Dong F, Gong H, Xu G, Wang K, Liu F, Pan L, Zhang L, Yan Y, Gaisano H, He Y, Shan G. Association between Indices of Body Composition and Abnormal Metabolic Phenotype in Normal-Weight Chinese Adults. International Journal of Environmental Research and Public Health. 14. PMID 28387701 DOI: 10.3390/Ijerph14040391 |
0.206 |
|
| 2018 |
Li D, Guo G, Xia L, Yang X, Zhang B, Liu F, Ma J, Hu Z, Li Y, Li W, Jiang J, Gaisano H, Shan G, He Y. Relative Handgrip Strength Is Inversely Associated with Metabolic Profile and Metabolic Disease in the General Population in China. Frontiers in Physiology. 9: 59. PMID 29459831 DOI: 10.3389/Fphys.2018.00059 |
0.206 |
|
| 2023 |
Xia Z, You W, Li Y, Li F, Hao S, Sun Y, Li N, Lin L, Dou J, Su X, Zhai Q, Zuo Y, Zhang Y, Gaisano HY, Zheng D, et al. Association between residual islet beta-cell function and achieving the target of time in range in inpatients with T2DM undergoing anti-diabetic treatment: an observation study. Diabetes, Obesity & Metabolism. PMID 36811214 DOI: 10.1111/dom.15026 |
0.202 |
|
| 2022 |
Xia Z, Song L, Fang D, You W, Li F, Zheng D, Li Y, Lin L, Dou J, Su X, Zhai Q, Zuo Y, Zhang Y, Gaisano HY, Jiang J, et al. Higher systolic blood pressure is specifically associated with better islet beta-cell function in T2DM patients with high glycemic level. Cardiovascular Diabetology. 21: 283. PMID 36536433 DOI: 10.1186/s12933-022-01723-1 |
0.195 |
|
| 2021 |
Mareninova OA, Vegh ET, Shalbueva N, Wightman CJ, Dillon DL, Malla S, Xie Y, Takahashi T, Rakonczay Z, French SW, Gaisano HY, Gorelick FS, Pandol SJ, Bensinger SJ, Davidson NO, et al. Dysregulation of mannose-6-phosphate dependent cholesterol homeostasis in acinar cells mediates pancreatitis. The Journal of Clinical Investigation. PMID 34128834 DOI: 10.1172/JCI146870 |
0.194 |
|
| 1998 |
Lau H, Salapatek A, Sheu L, Gaisano H, Diamant N. SNAP-23, SNAP-25 and VAMP-2 are found in feline esophageal smooth muscle Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)83206-X |
0.194 |
|
| 2007 |
Leung YM, Kwan EP, Ng B, Kang Y, Gaisano HY. SNAREing Voltage-Gated K+ and ATP-Sensitive K+ Channels: Tuning β-Cell Excitability with Syntaxin-1A and Other Exocytotic Proteins. Endocrine Reviews. 28: 653-663. PMID 28199496 DOI: 10.1210/er.2007-0010 |
0.194 |
|
| 2020 |
Wen J, Wang A, Liu G, Wang M, Zuo Y, Li W, Zhai Q, Mu Y, Gaisano HY, He Y, Dou J. Elevated triglyceride-glucose (TyG) index predicts incidence of Prediabetes: a prospective cohort study in China. Lipids in Health and Disease. 19: 226. PMID 33059672 DOI: 10.1186/s12944-020-01401-9 |
0.187 |
|
| 2021 |
Mareninova OA, Dillon DL, Wightman CJM, Yakubov I, Takahashi T, Gaisano HY, Munson K, Ohmuraya M, Dawson D, Gukovsky I, Gukovskaya AS. Rab9 mediates pancreatic autophagy switch from canonical to noncanonical, aggravating experimental pancreatitis. Cellular and Molecular Gastroenterology and Hepatology. PMID 34610499 DOI: 10.1016/j.jcmgh.2021.09.017 |
0.181 |
|
| 2022 |
Huang Y, Takahashi T, Gaisano H, Rakugi H, Yamamoto K. A live-imaging protocol for tracking receptor dynamics in single cells. Star Protocols. 3: 101347. PMID 35509972 DOI: 10.1016/j.xpro.2022.101347 |
0.166 |
|
| 2011 |
Gaisano HY, Go VLW. Memorial Tribute to Yang Kwong Chen, MD Pancreas. 40: 337-338. DOI: 10.1097/Mpa.0B013E31820Eeb64 |
0.166 |
|
| 2019 |
Gaisano HY, Jonas JC, Gloyn AL. Editorial Overview: "Islet Biology in Type 2 Diabetes". Journal of Molecular Biology. PMID 32005524 DOI: 10.1016/J.Jmb.2019.12.032 |
0.157 |
|
| 2021 |
Takahashi T, Huang Y, Yamamoto K, Hamano G, Kakino A, Kang F, Imaizumi Y, Takeshita H, Nozato Y, Nozato S, Yokoyama S, Nagasawa M, Kawai T, Takeda M, Fujimoto T, ... ... Gaisano HY, et al. The endocytosis of oxidized LDL via the activation of the angiotensin II type 1 receptor. Iscience. 24: 102076. PMID 33659870 DOI: 10.1016/j.isci.2021.102076 |
0.152 |
|
| 2015 |
Yu Y, Wang J, Kang R, Dong J, Zhang Y, Liu F, Yan Y, Zhu R, Xia L, Peng X, Zhang L, He D, Gaisano HY, Chen Z, He Y. Erratum to: Association of KCNB1 polymorphisms with lipid metabolisms and insulin resistance: a case-control design of population-based cross-sectional study in Chinese Han population. Lipids in Health and Disease. 14: 144. PMID 26545729 DOI: 10.1186/s12944-015-0144-9 |
0.116 |
|
| 2023 |
Huang M, Bin NR, Rai J, Ma K, Chow CH, Eide S, Harada H, Xiao J, Feng D, Sun HS, Feng ZP, Gaisano HY, Pessin JE, Monnier PP, Okamoto K, et al. Neuronal SNAP-23 is critical for synaptic plasticity and spatial memory independently of NMDA receptor regulation. Iscience. 26: 106664. PMID 37168570 DOI: 10.1016/j.isci.2023.106664 |
0.114 |
|
| 2023 |
Yadav J, Liang T, Qin T, Nathan N, Schwenger KJP, Pickel L, Xie L, Lei H, Winer DA, Maughan H, Robertson SJ, Woo M, Lou W, Banks K, Jackson T, ... ... Gaisano HY, et al. Gut microbiome modified by bariatric surgery improves insulin sensitivity and correlates with increased brown fat activity and energy expenditure. Cell Reports. Medicine. 4: 101051. PMID 37196633 DOI: 10.1016/j.xcrm.2023.101051 |
0.111 |
|
| 2022 |
Ghorbani Y, Schwenger KJ, Sharma D, Jung H, Yadav J, Xu W, Lou W, Poutanen S, Hota SS, Comelli EM, Philpott D, Jackson TD, Okrainec A, Gaisano HY, Allard JP. Effect of Fecal Microbial Transplant via colonoscopy in patients with severe obesity and insulin resistance: a randomized double-blind, placebo-controlled phase 2 trial. Diabetes, Obesity & Metabolism. PMID 36239189 DOI: 10.1111/dom.14891 |
0.098 |
|
| 2020 |
Scheers I, Chavhan GB, Chami R, Carman N, Scaini V, Gaisano H, Marcon M, Gonska T. Clinical Characteristics and Long-term Outcomes of Children With Fibrosing Pancreatitis. Journal of Pediatric Gastroenterology and Nutrition. 70: 801-807. PMID 32443035 DOI: 10.1097/MPG.0000000000002726 |
0.089 |
|
| 2022 |
Rafiei N, Moghadam MG, Au A, Regeenes R, Chidambaram S, Liang T, Wang Y, Yip CM, Gaisano H, Rocheleau JV. Design of a versatile microfluidic device for imaging precision-cut-tissue slices. Biofabrication. PMID 35793653 DOI: 10.1088/1758-5090/ac7eea |
0.062 |
|
| 2022 |
Zhai Q, Dou J, Wen J, Wang M, Zuo Y, Su X, Zhang Y, Gaisano H, Mu Y, He Y. Association between changes in lipid indexes and early progression of kidney dysfunction in participants with normal estimated glomerular filtration rate: a prospective cohort study. Endocrine. PMID 35239125 DOI: 10.1007/s12020-022-03012-z |
0.045 |
|
| 2021 |
Zhai Q, Wen J, Wang M, Zuo Y, Su X, Zhang Y, Gaisano H, He Y. Glomerular Hyperfiltration Interacts With Abnormal Metabolism to Enhance Arterial Stiffness in Middle-Aged and Elderly People. Frontiers in Medicine. 8: 732413. PMID 34746175 DOI: 10.3389/fmed.2021.732413 |
0.042 |
|
| 2021 |
Zuo Y, Zheng D, Chen S, Yang X, Yan Y, Liu F, Tian X, Wang M, Su X, Wen J, Zhai Q, Zhang Y, Gaisano HY, Wu S, Wang A, et al. Baseline and Cumulative Blood Pressure in Predicting the Occurrence of Cardiovascular Events. Frontiers in Cardiovascular Medicine. 8: 735679. PMID 34621801 DOI: 10.3389/fcvm.2021.735679 |
0.025 |
|
| 2018 |
Dolai S, Gaisano H. Reply. Gastroenterology. 155: 1274. PMID 30236557 DOI: 10.1053/j.gastro.2018.09.025 |
0.01 |
|
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