| Year |
Citation |
Score |
| 2023 |
Coloma J, Gonzalez-Rodriguez N, Balaguer FA, Gmurczyk K, Aicart-Ramos C, Nuero ÓM, Luque-Ortega JR, Calugaru K, Lue NF, Moreno-Herrero F, Llorca O. Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity. Nucleic Acids Research. 51: 668-686. PMID 36629261 DOI: 10.1093/nar/gkac1261 |
0.367 |
|
| 2022 |
Serna M, González-Corpas A, Cabezudo S, López-Perrote A, Degliesposti G, Zarzuela E, Skehel JM, Muñoz J, Llorca O. CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8. Nucleic Acids Research. 50: 1128-1146. PMID 34951455 DOI: 10.1093/nar/gkab1267 |
0.354 |
|
| 2021 |
Pal M, Muñoz-Hernandez H, Bjorklund D, Zhou L, Degliesposti G, Skehel JM, Hesketh EL, Thompson RF, Pearl LH, Llorca O, Prodromou C. Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone. Cell Reports. 36: 109317. PMID 34233195 DOI: 10.1016/j.celrep.2021.109317 |
0.399 |
|
| 2020 |
Zimmermann F, Serna M, Ezquerra A, Fernandez-Leiro R, Llorca O, Luders J. Assembly of the asymmetric human γ-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase. Science Advances. 6. PMID 33355144 DOI: 10.1126/sciadv.abe0894 |
0.33 |
|
| 2020 |
López-Perrote A, Hug N, González-Corpas A, Rodríguez CF, Serna M, García-Martín C, Boskovic J, Fernandez-Leiro R, Caceres JF, Llorca O. Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM. Elife. 9. PMID 33205750 DOI: 10.7554/eLife.63042 |
0.337 |
|
| 2020 |
Dauden MI, López-Perrote A, Llorca O. RUVBL1-RUVBL2 AAA-ATPase: a versatile scaffold for multiple complexes and functions. Current Opinion in Structural Biology. 67: 78-85. PMID 33129013 DOI: 10.1016/j.sbi.2020.08.010 |
0.387 |
|
| 2020 |
Acebrón I, Righetto RD, Schoenherr C, de Buhr S, Redondo P, Culley J, Rodríguez CF, Daday C, Biyani N, Llorca O, Byron A, Chami M, Gräter F, Boskovic J, Frame MC, et al. Structural basis of Focal Adhesion Kinase activation on lipid membranes. The Embo Journal. e104743. PMID 32779739 DOI: 10.15252/Embj.2020104743 |
0.336 |
|
| 2020 |
Rodríguez CF, Llorca O. RPAP3 C-Terminal Domain: A Conserved Domain for the Assembly of R2TP Co-Chaperone Complexes. Cells. 9. PMID 32384603 DOI: 10.3390/Cells9051139 |
0.493 |
|
| 2020 |
Rodríguez CF, Pal M, Muñoz-Hernandez H, Pearl LH, Llorca O. Modeling of a 14 kDa RUVBL2-Binding Domain with Medium Resolution Cryo-EM Density. Journal of Chemical Information and Modeling. PMID 32175735 DOI: 10.1021/Acs.Jcim.9B01095 |
0.429 |
|
| 2019 |
Famelis N, Rivera-Calzada A, Degliesposti G, Wingender M, Mietrach N, Skehel JM, Fernandez-Leiro R, Böttcher B, Schlosser A, Llorca O, Geibel S. Architecture of the mycobacterial type VII secretion system. Nature. PMID 31597161 DOI: 10.1038/S41586-019-1633-1 |
0.399 |
|
| 2019 |
Muñoz-Hernández H, Pal M, Rodríguez CF, Fernandez-Leiro R, Prodromou C, Pearl LH, Llorca O. Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Science Advances. 5: eaaw1616. PMID 31049401 DOI: 10.1126/Sciadv.Aaw1616 |
0.497 |
|
| 2018 |
Muñoz-Hernández H, Pal M, Rodríguez CF, Prodromou C, Pearl LH, Llorca O. Advances on the Structure of the R2TP/Prefoldin-like Complex. Advances in Experimental Medicine and Biology. 1106: 73-83. PMID 30484153 DOI: 10.1007/978-3-030-00737-9_5 |
0.477 |
|
| 2018 |
Martino F, Pal M, Muñoz-Hernández H, Rodríguez CF, Núñez-Ramírez R, Gil-Carton D, Degliesposti G, Skehel JM, Roe SM, Prodromou C, Pearl LH, Llorca O. RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Nature Communications. 9: 1501. PMID 29662061 DOI: 10.1038/S41467-018-03942-1 |
0.469 |
|
| 2017 |
Huecas S, Ramírez-Aportela E, Vergoñós A, Núñez-Ramírez R, Llorca O, Díaz JF, Juan-Rodríguez D, Oliva MA, Castellen P, Andreu JM. Self-Organization of FtsZ Polymers in Solution Reveals Spacer Role of the Disordered C-Terminal Tail. Biophysical Journal. 113: 1831-1844. PMID 29045877 DOI: 10.1016/J.Bpj.2017.08.046 |
0.366 |
|
| 2017 |
de Jorge EG, Yebenes H, Serna M, Tortajada A, Llorca O, de Córdoba SR. How novel structures inform understanding of complement function. Seminars in Immunopathology. PMID 28808775 DOI: 10.1007/S00281-017-0643-Z |
0.415 |
|
| 2017 |
Rivera-Calzada A, Pal M, Muñoz-Hernández H, Luque-Ortega JR, Gil-Carton D, Degliesposti G, Skehel JM, Prodromou C, Pearl LH, Llorca O. The Structure of the R2TP Complex Defines a Platform for Recruiting Diverse Client Proteins to the HSP90 Molecular Chaperone System. Structure (London, England : 1993). PMID 28648606 DOI: 10.1016/J.Str.2017.05.016 |
0.51 |
|
| 2017 |
López-Perrote A, Harrison RE, Subías M, Alcorlo M, Rodríguez de Córdoba S, Morikis D, Llorca O. Ionic tethering contributes to the conformational stability and function of complement C3b. Molecular Immunology. 85: 137-147. PMID 28254726 DOI: 10.1016/J.Molimm.2016.12.015 |
0.41 |
|
| 2017 |
Fuentes-Pérez ME, Núñez-Ramírez R, Martín-González A, Juan-Rodríguez D, Llorca O, Moreno-Herrero F, Oliva MA. TubZ filament assembly dynamics requires the flexible C-terminal tail. Scientific Reports. 7: 43342. PMID 28230082 DOI: 10.1038/Srep43342 |
0.429 |
|
| 2017 |
Subías Hidalgo M, Yébenes H, Rodríguez-Gallego C, Martín-Ambrosio A, Domínguez M, Tortajada A, Rodríguez de Córdoba S, Llorca O. Functional and structural characterization of four mouse monoclonal antibodies to complement C3 with potential therapeutic and diagnostic applications. European Journal of Immunology. 47: 504-515. PMID 28083930 DOI: 10.1002/Eji.201646758 |
0.338 |
|
| 2016 |
Melero R, Hug N, López-Perrote A, Yamashita A, Cáceres JF, Llorca O. The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation. Nature Communications. 7: 10585. PMID 26841701 DOI: 10.1038/Ncomms10585 |
0.712 |
|
| 2016 |
López-Perrote A, Castaño R, Melero R, Zamarro T, Kurosawa H, Ohnishi T, Uchiyama A, Aoyagi K, Buchwald G, Kataoka N, Yamashita A, Llorca O. Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex. Nucleic Acids Research. 44: 1909-23. PMID 26740584 DOI: 10.1093/Nar/Gkv1527 |
0.702 |
|
| 2016 |
Melero R, Hug N, Lopez-Perrote A, Yamashita A, Caceres JF, Llorca O. The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation Nature Communications. 7. DOI: 10.1038/ncomms10585 |
0.62 |
|
| 2015 |
Alcorlo M, López-Perrote A, Delgado S, Yébenes H, Subías M, Rodríguez-Gallego C, Rodríguez de Córdoba S, Llorca O. Structural insights on complement activation. The Febs Journal. 282: 3883-91. PMID 26250513 DOI: 10.1111/Febs.13399 |
0.429 |
|
| 2015 |
Matias PM, Baek SH, Bandeiras TM, Dutta A, Houry WA, Llorca O, Rosenbaum J. The AAA+ proteins Pontin and Reptin enter adult age: from understanding their basic biology to the identification of selective inhibitors. Frontiers in Molecular Biosciences. 2: 17. PMID 25988184 DOI: 10.3389/Fmolb.2015.00017 |
0.347 |
|
| 2015 |
Martínez-Barricarte R, Heurich M, López-Perrote A, Tortajada A, Pinto S, López-Trascasa M, Sánchez-Corral P, Morgan BP, Llorca O, Harris CL, Rodríguez de Córdoba S. The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome. Molecular Immunology. 66: 263-73. PMID 25879158 DOI: 10.1016/J.Molimm.2015.03.248 |
0.328 |
|
| 2015 |
Melero R, Moro F, Pérez-Calvo MÁ, Perales-Calvo J, Quintana-Gallardo L, Llorca O, Muga A, Valpuesta JM. Modulation of the chaperone DnaK allosterism by the nucleotide exchange factor GrpE Journal of Biological Chemistry. 290: 10083-10092. PMID 25739641 DOI: 10.1074/Jbc.M114.623371 |
0.714 |
|
| 2015 |
Torreira E, Moreno-Del Álamo M, Fuentes-Perez ME, Fernández C, Martín-Benito J, Moreno-Herrero F, Giraldo R, Llorca O. Amyloidogenesis of bacterial prionoid RepA-WH1 recapitulates dimer to monomer transitions of RepA in DNA replication initiation. Structure (London, England : 1993). 23: 183-9. PMID 25543255 DOI: 10.1016/J.Str.2014.11.007 |
0.389 |
|
| 2014 |
Melero R, Uchiyama A, Castaño R, Kataoka N, Kurosawa H, Ohno S, Yamashita A, Llorca O. Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD. Structure (London, England : 1993). 22: 1105-19. PMID 25002321 DOI: 10.1016/J.Str.2014.05.015 |
0.721 |
|
| 2014 |
López-Perrote A, Alatwi HE, Torreira E, Ismail A, Ayora S, Downs JA, Llorca O. Structure of Yin Yang 1 oligomers that cooperate with RuvBL1-RuvBL2 ATPases. The Journal of Biological Chemistry. 289: 22614-29. PMID 24990942 DOI: 10.1074/Jbc.M114.567040 |
0.46 |
|
| 2014 |
Barreira M, Fabbiano S, Couceiro JR, Torreira E, Martínez-Torrecuadrada JL, Montoya G, Llorca O, Bustelo XR. The C-terminal SH3 domain contributes to the intramolecular inhibition of Vav family proteins. Science Signaling. 7: ra35. PMID 24736456 DOI: 10.1126/Scisignal.2004993 |
0.439 |
|
| 2014 |
Paixão-Cavalcante D, Torreira E, Lindorfer MA, Rodriguez de Cordoba S, Morgan BP, Taylor RP, Llorca O, Harris CL. A humanized antibody that regulates the alternative pathway convertase: potential for therapy of renal disease associated with nephritic factors. Journal of Immunology (Baltimore, Md. : 1950). 192: 4844-51. PMID 24729617 DOI: 10.4049/Jimmunol.1303131 |
0.361 |
|
| 2014 |
Jin Q, Sorzano CO, de la Rosa-Trevín JM, Bilbao-Castro JR, Núñez-Ramírez R, Llorca O, Tama F, Jonić S. Iterative elastic 3D-to-2D alignment method using normal modes for studying structural dynamics of large macromolecular complexes. Structure (London, England : 1993). 22: 496-506. PMID 24508340 DOI: 10.1016/J.Str.2014.01.004 |
0.346 |
|
| 2013 |
Alcorlo M, Tortajada A, Rodríguez de Córdoba S, Llorca O. Structural basis for the stabilization of the complement alternative pathway C3 convertase by properdin. Proceedings of the National Academy of Sciences of the United States of America. 110: 13504-9. PMID 23901101 DOI: 10.1073/Pnas.1309618110 |
0.369 |
|
| 2013 |
Tortajada A, Yébenes H, Abarrategui-Garrido C, Anter J, García-Fernández JM, Martínez-Barricarte R, Alba-Domínguez M, Malik TH, Bedoya R, Cabrera Pérez R, López Trascasa M, Pickering MC, Harris CL, Sánchez-Corral P, Llorca O, et al. C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation. The Journal of Clinical Investigation. 123: 2434-46. PMID 23728178 DOI: 10.1172/Jci68280 |
0.379 |
|
| 2013 |
Llorca O. Structural insights into nonsense-mediated mRNA decay (NMD) by electron microscopy. Current Opinion in Structural Biology. 23: 161-7. PMID 23102542 DOI: 10.1016/J.Sbi.2012.10.004 |
0.329 |
|
| 2013 |
Alcorlo M, Cordoba SRd, Llorca O. Electron microscopy of properdin in complex with C3bBb convertase Molecular Immunology. 56: 261. DOI: 10.1016/J.Molimm.2013.05.064 |
0.345 |
|
| 2012 |
López-Perrote A, Muñoz-Hernández H, Gil D, Llorca O. Conformational transitions regulate the exposure of a DNA-binding domain in the RuvBL1-RuvBL2 complex. Nucleic Acids Research. 40: 11086-99. PMID 23002137 DOI: 10.1093/Nar/Gks871 |
0.515 |
|
| 2012 |
Hernández-Rocamora VM, García-Montañés C, Rivas G, Llorca O. Reconstitution of the Escherichia coli cell division ZipA-FtsZ complexes in nanodiscs as revealed by electron microscopy. Journal of Structural Biology. 180: 531-8. PMID 23000704 DOI: 10.1016/J.Jsb.2012.08.013 |
0.416 |
|
| 2012 |
Hadders MA, Bubeck D, Roversi P, Hakobyan S, Forneris F, Morgan BP, Pangburn MK, Llorca O, Lea SM, Gros P. Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9. Cell Reports. 1: 200-7. PMID 22832194 DOI: 10.1016/J.Celrep.2012.02.003 |
0.438 |
|
| 2012 |
Melero R, Buchwald G, Castaño R, Raabe M, Gil D, Lázaro M, Urlaub H, Conti E, Llorca O. The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3' end. Nature Structural & Molecular Biology. 19: 498-505, S1-2. PMID 22522823 DOI: 10.1038/Nsmb.2287 |
0.716 |
|
| 2012 |
Alcorlo M, Rodriguez-Gallego C, Yebenes H, Tortajada A, Subias M, Cordoba SRd, Llorca O. Electron microscopy reveals coexistence of distinct conformations of iC3b Immunobiology. 217: 1166. DOI: 10.1016/J.Imbio.2012.08.108 |
0.316 |
|
| 2011 |
Chen S, Bubeck D, MacDonald BT, Liang WX, Mao JH, Malinauskas T, Llorca O, Aricescu AR, Siebold C, He X, Jones EY. Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling. Developmental Cell. 21: 848-61. PMID 22000855 DOI: 10.1016/J.Devcel.2011.09.007 |
0.395 |
|
| 2011 |
Alcorlo M, MartÃnez-Barricarte R, Fernández FJ, RodrÃguez-Gallego C, Round A, Vega MC, Harris CL, de Cordoba SR, Llorca O. Unique structure of iC3b resolved at a resolution of 24 Ã… by 3D-electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 108: 13236-40. PMID 21788512 DOI: 10.1073/Pnas.1106746108 |
0.374 |
|
| 2011 |
Núñez-Ramírez R, Klinge S, Sauguet L, Melero R, Recuero-Checa MA, Kilkenny M, Perera RL, García-Alvarez B, Hall RJ, Nogales E, Pellegrini L, Llorca O. Flexible tethering of primase and DNA Pol α in the eukaryotic primosome. Nucleic Acids Research. 39: 8187-99. PMID 21715379 DOI: 10.1093/Nar/Gkr534 |
0.691 |
|
| 2011 |
Morris EP, Rivera-Calzada A, da Fonseca PC, Llorca O, Pearl LH, Spagnolo L. Evidence for a remodelling of DNA-PK upon autophosphorylation from electron microscopy studies. Nucleic Acids Research. 39: 5757-67. PMID 21450809 DOI: 10.1093/Nar/Gkr146 |
0.36 |
|
| 2011 |
García-Alvarez B, Melero R, Dias FM, Prates JA, Fontes CM, Smith SP, Romão MJ, Carvalho AL, Llorca O. Molecular architecture and structural transitions of a Clostridium thermocellum mini-cellulosome. Journal of Molecular Biology. 407: 571-80. PMID 21315080 DOI: 10.1016/J.Jmb.2011.01.060 |
0.705 |
|
| 2011 |
Arias-Palomo E, Yamashita A, Fernández IS, Núñez-Ramírez R, Bamba Y, Izumi N, Ohno S, Llorca O. The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8. Genes & Development. 25: 153-64. PMID 21245168 DOI: 10.1101/Gad.606911 |
0.415 |
|
| 2011 |
Bubeck D, Roversi P, Donev R, Morgan BP, Llorca O, Lea SM. Structure of human complement C8, a precursor to membrane attack. Journal of Molecular Biology. 405: 325-30. PMID 21073882 DOI: 10.1016/J.Jmb.2010.10.031 |
0.366 |
|
| 2011 |
Rodríguez de Córdoba S, Harris CL, Morgan BP, Llorca O. Lessons from functional and structural analyses of disease-associated genetic variants in the complement alternative pathway. Biochimica Et Biophysica Acta. 1812: 12-22. PMID 20837143 DOI: 10.1016/J.Bbadis.2010.09.002 |
0.347 |
|
| 2011 |
Fernández IS, Yamashita A, Arias-Palomo E, Bamba Y, Bartolomé RA, Canales MA, Teixidó J, Ohno S, Llorca O. Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex. Nucleic Acids Research. 39: 347-58. PMID 20817927 DOI: 10.1093/Nar/Gkq749 |
0.496 |
|
| 2011 |
Alcorlo M, Martínez-Barricarte R, Fernández FJ, Rodríguez-Gallego C, Round A, Vega MC, Harris CL, De Cordoba SR, Llorca O. Unique structure of iC3b resolved at a resolution of 24 Å by 3D-electron microscopy (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 32, (13236-13240) DOI: 10.1073/pnas. 1106746108) Proceedings of the National Academy of Sciences of the United States of America. 108: 16481. DOI: 10.1073/Pnas.1112875108 |
0.301 |
|
| 2010 |
MartÃnez-Barricarte R, Heurich M, Valdes-Cañedo F, Vazquez-Martul E, Torreira E, Montes T, Tortajada A, Pinto S, Lopez-Trascasa M, Morgan BP, Llorca O, Harris CL, RodrÃguez de Córdoba S. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. The Journal of Clinical Investigation. 120: 3702-12. PMID 20852386 DOI: 10.1172/Jci43343 |
0.311 |
|
| 2010 |
Durante-Rodríguez G, Valderrama JA, Mancheño JM, Rivas G, Alfonso C, Arias-Palomo E, Llorca O, García JL, Díaz E, Carmona M. Biochemical characterization of the transcriptional regulator BzdR from Azoarcus sp. CIB. The Journal of Biological Chemistry. 285: 35694-705. PMID 20826820 DOI: 10.1074/Jbc.M110.143503 |
0.455 |
|
| 2010 |
Resa-Infante P, Recuero-Checa MA, Zamarreño N, Llorca O, Ortín J. Structural and functional characterization of an influenza virus RNA polymerase-genomic RNA complex. Journal of Virology. 84: 10477-87. PMID 20702645 DOI: 10.1128/Jvi.01115-10 |
0.385 |
|
| 2010 |
Sánchez-Gómez FJ, Díez-Dacal B, Pajares MA, Llorca O, Pérez-Sala D. Cyclopentenone prostaglandins with dienone structure promote cross-linking of the chemoresistance-inducing enzyme glutathione transferase P1-1. Molecular Pharmacology. 78: 723-33. PMID 20631055 DOI: 10.1124/Mol.110.065391 |
0.327 |
|
| 2010 |
Andreu JM, Schaffner-Barbero C, Huecas S, Alonso D, Lopez-Rodriguez ML, Ruiz-Avila LB, Núñez-Ramírez R, Llorca O, Martín-Galiano AJ. The antibacterial cell division inhibitor PC190723 is an FtsZ polymer-stabilizing agent that induces filament assembly and condensation. The Journal of Biological Chemistry. 285: 14239-46. PMID 20212044 DOI: 10.1074/Jbc.M109.094722 |
0.326 |
|
| 2009 |
Torreira E, Tortajada A, Montes T, Rodríguez de Córdoba S, Llorca O. Coexistence of closed and open conformations of complement factor B in the alternative pathway C3bB(Mg2+) proconvertase. Journal of Immunology (Baltimore, Md. : 1950). 183: 7347-51. PMID 19890040 DOI: 10.4049/Jimmunol.0902310 |
0.369 |
|
| 2009 |
Rodríguez-Pulido A, Martín-Molina A, Rodríguez-Beas C, Llorca O, Aicart E, Junquera E. A theoretical and experimental approach to the compaction process of DNA by dioctadecyldimethylammonium bromide/zwitterionic mixed liposomes. The Journal of Physical Chemistry. B. 113: 15648-61. PMID 19877682 DOI: 10.1021/Jp906777G |
0.314 |
|
| 2009 |
Recuero-Checa MA, Doré AS, Arias-Palomo E, Rivera-Calzada A, Scheres SH, Maman JD, Pearl LH, Llorca O. Electron microscopy of Xrcc4 and the DNA ligase IV-Xrcc4 DNA repair complex. Dna Repair. 8: 1380-9. PMID 19837014 DOI: 10.1016/J.Dnarep.2009.09.007 |
0.48 |
|
| 2009 |
Klinge S, Núñez-Ramírez R, Llorca O, Pellegrini L. 3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases. The Embo Journal. 28: 1978-87. PMID 19494830 DOI: 10.1038/Emboj.2009.150 |
0.418 |
|
| 2009 |
Boer DR, Ruíz-Masó JA, López-Blanco JR, Blanco AG, Vives-Llàcer M, Chacón P, Usón I, Gomis-Rüth FX, Espinosa M, Llorca O, del Solar G, Coll M. Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains. The Embo Journal. 28: 1666-78. PMID 19440202 DOI: 10.1038/Emboj.2009.125 |
0.407 |
|
| 2009 |
Arias-Palomo E, Recuero-Checa MA, Bustelo XR, Llorca O. Conformational rearrangements upon Syk auto-phosphorylation. Biochimica Et Biophysica Acta. 1794: 1211-7. PMID 19409513 DOI: 10.1016/J.Bbapap.2009.04.010 |
0.442 |
|
| 2009 |
Torreira E, Tortajada A, Montes T, Rodríguez de Córdoba S, Llorca O. 3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase. Proceedings of the National Academy of Sciences of the United States of America. 106: 882-7. PMID 19136636 DOI: 10.1073/Pnas.0810860106 |
0.497 |
|
| 2009 |
Tortajada A, Torreira E, Montes T, Llorca O, Córdoba SRd. 3D models of the C3bB and C3bBb complexes: A structural framework to understand regulatory mechanisms and disease-associated mutations Molecular Immunology. 46: 2820. DOI: 10.1016/J.Molimm.2009.05.192 |
0.321 |
|
| 2008 |
Torreira E, Jha S, López-Blanco JR, Arias-Palomo E, Chacón P, Cañas C, Ayora S, Dutta A, Llorca O. Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes. Structure (London, England : 1993). 16: 1511-20. PMID 18940606 DOI: 10.1016/J.Str.2008.08.009 |
0.487 |
|
| 2008 |
Rehmann H, Arias-Palomo E, Hadders MA, Schwede F, Llorca O, Bos JL. Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B. Nature. 455: 124-7. PMID 18660803 DOI: 10.1038/Nature07187 |
0.45 |
|
| 2008 |
Schuermann JP, Jiang J, Cuellar J, Llorca O, Wang L, Gimenez LE, Jin S, Taylor AB, Demeler B, Morano KA, Hart PJ, Valpuesta JM, Lafer EM, Sousa R. Structure of the Hsp110:Hsc70 nucleotide exchange machine. Molecular Cell. 31: 232-43. PMID 18550409 DOI: 10.1016/J.Molcel.2008.05.006 |
0.426 |
|
| 2008 |
Rodríguez-Pulido A, Aicart E, Llorca O, Junquera E. Compaction process of calf thymus DNA by mixed cationic-zwitterionic liposomes: a physicochemical study. The Journal of Physical Chemistry. B. 112: 2187-97. PMID 18220388 DOI: 10.1021/Jp7095828 |
0.302 |
|
| 2008 |
Llorca Ó. Extended and bent conformations of the mannose receptor family. Cellular and Molecular Life Sciences. 65: 1302-1310. PMID 18193159 DOI: 10.1007/S00018-007-7497-9 |
0.359 |
|
| 2008 |
Huecas S, Llorca O, Boskovic J, Martín-Benito J, Valpuesta JM, Andreu JM. Energetics and geometry of FtsZ polymers: nucleated self-assembly of single protofilaments. Biophysical Journal. 94: 1796-806. PMID 18024502 DOI: 10.1529/Biophysj.107.115493 |
0.354 |
|
| 2007 |
Arias-Palomo E, Recuero-Checa MA, Bustelo XR, Llorca O. 3D structure of Syk kinase determined by single-particle electron microscopy. Biochimica Et Biophysica Acta. 1774: 1493-9. PMID 18021750 DOI: 10.1016/J.Bbapap.2007.10.008 |
0.443 |
|
| 2007 |
Adami A, García-Alvarez B, Arias-Palomo E, Barford D, Llorca O. Structure of TOR and its complex with KOG1. Molecular Cell. 27: 509-16. PMID 17679098 DOI: 10.1016/J.Molcel.2007.05.040 |
0.49 |
|
| 2007 |
Torreira E, Schoehn G, Fernández Y, Jorba N, Ruigrok RW, Cusack S, Ortín J, Llorca O. Three-dimensional model for the isolated recombinant influenza virus polymerase heterotrimer. Nucleic Acids Research. 35: 3774-83. PMID 17517766 DOI: 10.1093/Nar/Gkm336 |
0.425 |
|
| 2007 |
Llorca O. Electron microscopy reconstructions of DNA repair complexes. Current Opinion in Structural Biology. 17: 215-20. PMID 17387012 DOI: 10.1016/J.Sbi.2007.03.009 |
0.386 |
|
| 2007 |
Rivera-Calzada A, Spagnolo L, Pearl LH, Llorca O. Structural model of full-length human Ku70-Ku80 heterodimer and its recognition of DNA and DNA-PKcs. Embo Reports. 8: 56-62. PMID 17159921 DOI: 10.1038/Sj.Embor.7400847 |
0.416 |
|
| 2007 |
Llorca O, Trujillo A, Blanco FJ, Bernabeu C. Structural model of human endoglin, a transmembrane receptor responsible for hereditary hemorrhagic telangiectasia. Journal of Molecular Biology. 365: 694-705. PMID 17081563 DOI: 10.1016/J.Jmb.2006.10.015 |
0.417 |
|
| 2006 |
Burgo PD, Aicart E, Llorca O, Junquera E. Cationic prevesicle and vesicle nanoaggregates: an experimental and theoretical study. The Journal of Physical Chemistry. B. 110: 23524-39. PMID 17107208 DOI: 10.1021/Jp0645768 |
0.32 |
|
| 2006 |
Gayarre J, Sánchez D, Sánchez-Gómez FJ, Terrón MC, Llorca O, Pérez-Sala D. Addition of electrophilic lipids to actin alters filament structure. Biochemical and Biophysical Research Communications. 349: 1387-93. PMID 16979589 DOI: 10.1016/J.Bbrc.2006.09.005 |
0.363 |
|
| 2006 |
Llorca O, Betti M, González JM, Valencia A, Márquez AJ, Valpuesta JM. The three-dimensional structure of an eukaryotic glutamine synthetase: functional implications of its oligomeric structure. Journal of Structural Biology. 156: 469-79. PMID 16884924 DOI: 10.1016/J.Jsb.2006.06.003 |
0.411 |
|
| 2006 |
Spagnolo L, Rivera-Calzada A, Pearl LH, Llorca O. Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair. Molecular Cell. 22: 511-9. PMID 16713581 DOI: 10.1016/J.Molcel.2006.04.013 |
0.366 |
|
| 2006 |
Aicart E, del Burgo P, Llorca O, Junquera E. Electrochemical, microscopic, and spectroscopic characterization of prevesicle nanostructures and vesicles on mixed cationic surfactant systems. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 4027-36. PMID 16618141 DOI: 10.1021/La053474Q |
0.31 |
|
| 2006 |
Boskovic J, Arnold JN, Stilion R, Gordon S, Sim RB, Rivera-Calzada A, Wienke D, Isacke CM, Martinez-Pomares L, Llorca O. Structural model for the mannose receptor family uncovered by electron microscopy of Endo180 and the mannose receptor. The Journal of Biological Chemistry. 281: 8780-7. PMID 16452473 DOI: 10.1074/Jbc.M513277200 |
0.378 |
|
| 2005 |
Llorca O. Introduction to 3D reconstruction of macromolecules using single particle electron microscopy. Acta Pharmacologica Sinica. 26: 1153-64. PMID 16174429 DOI: 10.1111/J.1745-7254.2005.00203.X |
0.343 |
|
| 2005 |
Llorca O, Arias-Palomo E, Zugaza JL, Bustelo XR. Global conformational rearrangements during the activation of the GDP/GTP exchange factor Vav3. The Embo Journal. 24: 1330-40. PMID 15775967 DOI: 10.1038/Sj.Emboj.7600617 |
0.449 |
|
| 2005 |
Ruiz-Ferrer V, Boskovic J, Alfonso C, Rivas G, Llorca O, López-Abella D, López-Moya JJ. Structural analysis of tobacco etch potyvirus HC-pro oligomers involved in aphid transmission. Journal of Virology. 79: 3758-65. PMID 15731269 DOI: 10.1128/Jvi.79.6.3758-3765.2005 |
0.358 |
|
| 2005 |
Rivera-Calzada A, Maman JD, Maman JP, Spagnolo L, Pearl LH, Llorca O. Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs). Structure (London, England : 1993). 13: 243-55. PMID 15698568 DOI: 10.1016/J.Str.2004.12.006 |
0.438 |
|
| 2004 |
Llorca O, Pearl LH. Electron microscopy studies on DNA recognition by DNA-PK. Micron (Oxford, England : 1993). 35: 625-33. PMID 15288642 DOI: 10.1016/J.Micron.2004.05.004 |
0.388 |
|
| 2003 |
Boskovic J, Rivera-Calzada A, Maman JD, Chacón P, Willison KR, Pearl LH, Llorca O. Visualization of DNA-induced conformational changes in the DNA repair kinase DNA-PKcs. The Embo Journal. 22: 5875-82. PMID 14592984 DOI: 10.1093/Emboj/Cdg555 |
0.34 |
|
| 2003 |
Rivera-Calzada A, Robertson D, MacFadyen JR, Boskovic J, Isacke CM, Llorca O. Three-dimensional interplay among the ligand-binding domains of the urokinase-plasminogen-activator-receptor-associated protein, Endo180. Embo Reports. 4: 807-12. PMID 12856000 DOI: 10.1038/Sj.Embor.Embor898 |
0.422 |
|
| 2003 |
Llorca O, Rivera-Calzada A, Grantham J, Willison KR. Electron microscopy and 3D reconstructions reveal that human ATM kinase uses an arm-like domain to clamp around double-stranded DNA. Oncogene. 22: 3867-3874. PMID 12813460 DOI: 10.1038/Sj.Onc.1206649 |
0.419 |
|
| 2002 |
Llorca O, Martín-Benito J, Gómez-Puertas P, Ritco-Vonsovici M, Willison KR, Carrascosa JL, Valpuesta JM. Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin. Journal of Structural Biology. 135: 205-18. PMID 11580270 DOI: 10.1006/Jsbi.2001.4359 |
0.416 |
|
| 2002 |
McCormack EA, Llorca O, Carrascosa JL, Valpuesta JM, Willison KR. Point mutations in a hinge linking the small and large domains of beta-actin result in trapped folding intermediates bound to cytosolic chaperonin CCT. Journal of Structural Biology. 135: 198-204. PMID 11580269 DOI: 10.1006/Jsbi.2001.4385 |
0.376 |
|
| 2001 |
Llorca O, Martín-Benito J, Grantham J, Ritco-Vonsovici M, Willison KR, Carrascosa JL, Valpuesta JM. The 'sequential allosteric ring' mechanism in the eukaryotic chaperonin-assisted folding of actin and tubulin. The Embo Journal. 20: 4065-75. PMID 11483510 DOI: 10.1093/Emboj/20.15.4065 |
0.457 |
|
| 2001 |
Martín-Benito J, Area E, Ortega J, Llorca O, Valpuesta JM, Carrascosa JL, Ortín J. Three-dimensional reconstruction of a recombinant influenza virus ribonucleoprotein particle. Embo Reports. 2: 313-7. PMID 11306552 DOI: 10.1093/Embo-Reports/Kve063 |
0.375 |
|
| 2001 |
Llorca O, Martín-Benito J, Ritco-Vonsovici M, Grantham J, Hynes GM, Willison KR, Carrascosa JL, Valpuesta JM. Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi-native conformations. The Embo Journal. 19: 5971-9. PMID 11080144 DOI: 10.1093/Emboj/19.22.5971 |
0.447 |
|
| 2001 |
Galan A, Sot B, Llorca O, Carrascosa JL, Valpuesta JM, Muga A. Excluded volume effects on the refolding and assembly of an oligomeric protein. GroEL, a case study. The Journal of Biological Chemistry. 276: 957-64. PMID 11020386 DOI: 10.1074/Jbc.M006861200 |
0.374 |
|
| 2000 |
Donate LE, Llorca O, Bárcena M, Brown SE, Dixon NE, Carazo JM. pH-controlled quaternary states of hexameric DnaB helicase. Journal of Molecular Biology. 303: 383-93. PMID 11031115 DOI: 10.1006/Jmbi.2000.4132 |
0.595 |
|
| 2000 |
Carrascosa JL, Llorca O, Valpuesta JM. Structural comparison of prokaryotic and eukaryotic chaperonins. Micron (Oxford, England : 1993). 32: 43-50. PMID 10900379 DOI: 10.1016/S0968-4328(00)00027-5 |
0.408 |
|
| 2000 |
Ibarra B, Castón JR, Llorca O, Valle M, Valpuesta JM, Carrascosa JL. Topology of the components of the DNA packaging machinery in the phage phi29 prohead. Journal of Molecular Biology. 298: 807-15. PMID 10801350 DOI: 10.1006/Jmbi.2000.3712 |
0.443 |
|
| 2000 |
Grantham J, Llorca O, Valpuesta JM, Willison KR. Partial Occlusion of Both Cavities of the Eukaryotic Chaperonin with Antibody Has No Effect upon the Rates of β-Actin or α-Tubulin Folding Journal of Biological Chemistry. 275: 4587-4591. PMID 10671484 DOI: 10.1074/Jbc.275.7.4587 |
0.32 |
|
| 2000 |
Llorca O, McCormack EA, Hynes G, Grantham J, Cordell J, Carrascosa JL, Willison KR, Fernandez JJ, Valpuesta JM. Eukaryotic type II chaperonin CCT interacts with actin through specific subunits. Nature. 402: 693-6. PMID 10604479 DOI: 10.1038/45294 |
0.442 |
|
| 2000 |
Donate LE, Bárcena M, Llorca O, Dixon N, Carazo JM. Quaternary Polymorphism in Helicases and the DnaB.DnaC Complex Microscopy and Microanalysis. 6: 272-273. DOI: 10.1017/S1431927600033857 |
0.498 |
|
| 1999 |
Llorca O, Smyth MG, Carrascosa JL, Willison KR, Radermacher M, Steinbacher S, Valpuesta JM. 3D reconstruction of the ATP-bound form of CCT reveals the asymmetric folding conformation of a type II chaperonin. Nature Structural Biology. 6: 639-42. PMID 10404219 DOI: 10.1038/10689 |
0.392 |
|
| 1999 |
von Germar F, Galán A, Llorca O, Carrascosa JL, Valpuesta JM, Mäntele W, Muga A. Conformational changes generated in GroEL during ATP hydrolysis as seen by time-resolved infrared spectroscopy. The Journal of Biological Chemistry. 274: 5508-13. PMID 10026164 DOI: 10.1074/Jbc.274.9.5508 |
0.38 |
|
| 1999 |
Galán A, Llorca O, Valpuesta JM, Pérez-Pérez J, Carrascosa JL, Menéndez M, Bañuelos S, Muga A. ATP hydrolysis induces an intermediate conformational state in GroEL. European Journal of Biochemistry / Febs. 259: 347-55. PMID 9914513 DOI: 10.1046/J.1432-1327.1999.00045.X |
0.361 |
|
| 1998 |
Llorca O, Smyth MG, Marco S, Carrascosa JL, Willison KR, Valpuesta JM. ATP binding induces large conformational changes in the apical and equatorial domains of the eukaryotic chaperonin containing TCP-1 complex. The Journal of Biological Chemistry. 273: 10091-4. PMID 9553054 DOI: 10.1074/Jbc.273.17.10091 |
0.465 |
|
| 1997 |
Llorca O, Pérez-Pérez J, Carrascosa JL, Galán A, Muga A, Valpuesta JM. Effects of the inter-ring communication in GroEL structural and functional asymmetry. The Journal of Biological Chemistry. 272: 32925-32. PMID 9407071 DOI: 10.1074/Jbc.272.52.32925 |
0.357 |
|
| 1997 |
Llorca O, Marco S, Carrascosa JL, Valpuesta JM. Symmetric GroEL-GroES complexes can contain substrate simultaneously in both GroEL rings. Febs Letters. 405: 195-9. PMID 9089290 DOI: 10.1016/S0014-5793(97)00186-5 |
0.403 |
|
| 1997 |
Llorca O, Marco S, Carrascosa JL, Valpuesta JM. Conformational changes in the GroEL oligomer during the functional cycle. Journal of Structural Biology. 118: 31-42. PMID 9087913 DOI: 10.1006/Jsbi.1996.3832 |
0.375 |
|
| 1997 |
Llorca O, Schneider K, Carrascosa JL, Méndez E, Valpuesta JM. Role of the amino terminal domain in GroES oligomerization. Biochimica Et Biophysica Acta. 1337: 47-56. PMID 9003436 DOI: 10.1016/S0167-4838(96)00106-9 |
0.414 |
|
| 1996 |
Llorca O, Carrascosa JL, Valpuesta JM. Biochemical characterization of symmetric GroEL-GroES complexes. Evidence for a role in protein folding. The Journal of Biological Chemistry. 271: 68-76. PMID 8550627 DOI: 10.1074/Jbc.271.1.68 |
0.417 |
|
| 1995 |
Valencia A, Hubbard TJ, Muga A, Bañuelos S, Llorca O, Carrascosa JL, Valpuesta JM. Prediction of the structure of GroES and its interaction with GroEL. Proteins. 22: 199-209. PMID 7479694 DOI: 10.1002/Prot.340220302 |
0.307 |
|
| 1994 |
Llorca O, Marco S, Carrascosa JL, Valpuesta JM. The formation of symmetrical GroEL-GroES complexes in the presence of ATP. Febs Letters. 345: 181-6. PMID 7911087 DOI: 10.1016/0014-5793(94)00432-3 |
0.396 |
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