Year |
Citation |
Score |
2012 |
Shinkai Y, Iwamoto N, Miura T, Ishii T, Cho AK, Kumagai Y. Redox cycling of 1,2-naphthoquinone by thioredoxin1 through Cys32 and Cys35 causes inhibition of its catalytic activity and activation of ASK1/p38 signaling. Chemical Research in Toxicology. 25: 1222-30. PMID 22587396 DOI: 10.1021/Tx300069R |
0.311 |
|
2012 |
Kumagai Y, Shinkai Y, Miura T, Cho AK. The chemical biology of naphthoquinones and its environmental implications. Annual Review of Pharmacology and Toxicology. 52: 221-47. PMID 21942631 DOI: 10.1146/Annurev-Pharmtox-010611-134517 |
0.317 |
|
2011 |
Miura T, Kakehashi H, Shinkai Y, Egara Y, Hirose R, Cho AK, Kumagai Y. GSH-mediated S-transarylation of a quinone glyceraldehyde-3-phosphate dehydrogenase conjugate. Chemical Research in Toxicology. 24: 1836-44. PMID 21827172 DOI: 10.1021/Tx200025Y |
0.308 |
|
2011 |
Miura T, Shinkai Y, Jiang HY, Iwamoto N, Sumi D, Taguchi K, Yamamoto M, Jinno H, Tanaka-Kagawa T, Cho AK, Kumagai Y. Initial response and cellular protection through the Keap1/Nrf2 system during the exposure of primary mouse hepatocytes to 1,2-naphthoquinone. Chemical Research in Toxicology. 24: 559-67. PMID 21384861 DOI: 10.1021/Tx100427P |
0.325 |
|
2011 |
Verma V, Pakbin P, Cheung KL, Cho AK, Schauer JJ, Shafer MM, Kleinman MT, Sioutas C. Physicochemical and oxidative characteristics of semi-volatile components of quasi-ultrafine particles in an urban atmosphere Atmospheric Environment. 45: 1025-1033. DOI: 10.1016/J.Atmosenv.2010.10.044 |
0.303 |
|
2009 |
Jonsson J, Lindeke B, Cho AK. Oxidation of phenethylamine yielding tyramine by rat liver microsomes. Pharmacology & Toxicology. 37: 352-360. PMID 1242862 DOI: 10.1111/J.1600-0773.1975.Tb00853.X |
0.344 |
|
2009 |
Verma V, Ning Z, Cho AK, Schauer JJ, Shafer MM, Sioutas C. Redox activity of urban quasi-ultrafine particles from primary and secondary sources Atmospheric Environment. 43: 6360-6368. DOI: 10.1016/J.Atmosenv.2009.09.019 |
0.306 |
|
2008 |
Taguchi K, Shimada M, Fujii S, Sumi D, Pan X, Yamano S, Nishiyama T, Hiratsuka A, Yamamoto M, Cho AK, Froines JR, Kumagai Y. Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells. Free Radical Biology & Medicine. 44: 1645-55. PMID 18294972 DOI: 10.1016/J.Freeradbiomed.2008.01.024 |
0.308 |
|
2008 |
Melega WP, Jorgensen MJ, Laćan G, Way BM, Pham J, Morton G, Cho AK, Fairbanks LA. Long-term methamphetamine administration in the vervet monkey models aspects of a human exposure: brain neurotoxicity and behavioral profiles. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1441-52. PMID 17625500 DOI: 10.1038/Sj.Npp.1301502 |
0.315 |
|
2008 |
Shinyashiki M, Rodriguez CE, Di Stefano EW, Sioutas C, Delfino RJ, Kumagai Y, Froines JR, Cho AK. On the interaction between glyceraldehyde-3-phosphate dehydrogenase and airborne particles: Evidence for electrophilic species Atmospheric Environment. 42: 517-529. DOI: 10.1016/J.Atmosenv.2007.09.047 |
0.32 |
|
2007 |
Ntziachristos L, Froines JR, Cho AK, Sioutas C. Relationship between redox activity and chemical speciation of size-fractionated particulate matter. Particle and Fibre Toxicology. 4: 5. PMID 17555562 DOI: 10.1186/1743-8977-4-5 |
0.318 |
|
2006 |
O'Neil ML, Kuczenski R, Segal DS, Cho AK, Lacan G, Melega WP. Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge. Synapse (New York, N.Y.). 60: 465-73. PMID 16897726 DOI: 10.1002/Syn.20320 |
0.34 |
|
2005 |
Cho AK, Sioutas C, Miguel AH, Kumagai Y, Schmitz DA, Singh M, Eiguren-Fernandez A, Froines JR. Redox activity of airborne particulate matter at different sites in the Los Angeles Basin. Environmental Research. 99: 40-7. PMID 16053926 DOI: 10.1016/J.Envres.2005.01.003 |
0.319 |
|
2005 |
Segal DS, Kuczenski R, O'Neil ML, Melega WP, Cho AK. Prolonged exposure of rats to intravenous methamphetamine: behavioral and neurochemical characterization. Psychopharmacology. 180: 501-12. PMID 15959831 DOI: 10.1007/S00213-005-2188-4 |
0.326 |
|
2005 |
Rodriguez CE, Fukuto JM, Taguchi K, Froines J, Cho AK. The interactions of 9,10-phenanthrenequinone with glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a potential site for toxic actions. Chemico-Biological Interactions. 155: 97-110. PMID 15950210 DOI: 10.1016/J.Cbi.2005.05.002 |
0.561 |
|
2004 |
Rodriguez CE, Shinyashiki M, Froines J, Yu RC, Fukuto JM, Cho AK. An examination of quinone toxicity using the yeast Saccharomyces cerevisiae model system. Toxicology. 201: 185-96. PMID 15297032 DOI: 10.1016/J.Tox.2004.04.016 |
0.562 |
|
2004 |
Pan CJ, Schmitz DA, Cho AK, Froines J, Fukuto JM. Inherent redox properties of diesel exhaust particles: catalysis of the generation of reactive oxygen species by biological reductants. Toxicological Sciences : An Official Journal of the Society of Toxicology. 81: 225-32. PMID 15201441 DOI: 10.1093/Toxsci/Kfh199 |
0.541 |
|
2003 |
Segal DS, Kuczenski R, O'Neil ML, Melega WP, Cho AK. Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1730-40. PMID 12865898 DOI: 10.1038/Sj.Npp.1300247 |
0.32 |
|
2003 |
Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environmental Health Perspectives. 111: 455-60. PMID 12676598 DOI: 10.1289/Ehp.6000 |
0.306 |
|
2001 |
Narimatsu S, Arai T, Masubuchi Y, Horie T, Hosokawa M, Ueno K, Kataoka H, Yamamoto S, Ishikawa T, Cho AK. Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol. Biological & Pharmaceutical Bulletin. 24: 988-994. PMID 11558582 DOI: 10.1248/Bpb.24.988 |
0.341 |
|
1999 |
Cho AK, Melega WP, Kuczenski R, Segal DS, Schmitz DA. Caudate-putamen dopamine and stereotypy response profiles after intravenous and subcutaneous amphetamine. Synapse (New York, N.Y.). 31: 125-33. PMID 10024009 DOI: 10.1002/(Sici)1098-2396(199902)31:2<125::Aid-Syn5>3.0.Co;2-W |
0.329 |
|
1999 |
Cho AK, Narimatsu S, Kumagai Y. Metabolism of drugs of abuse by cytochromes P450 Addiction Biology. 4: 283-301. DOI: 10.1080/13556219971498 |
0.3 |
|
1997 |
Narimatsu S, Arai T, Watanabe T, Masubuchi Y, Horie T, Suzuki T, Ishikawa T, Tsutsui M, Kumagai Y, Cho AK. Covalent binding of a reactive metabolite derived from propranolol and its active metabolite 4-hydroxypropranolol to hepatic microsomal proteins of the rat. Chemical Research in Toxicology. 10: 289-295. PMID 9084908 DOI: 10.1021/Tx960165E |
0.331 |
|
1997 |
Yamada H, Shiiyama S, Soejimaohkuma T, Honda S, Kumagai Y, Cho AK, Oguri K, Yoshimura H. Deamination of amphetamines by cytochromes P450 : Studies on substrate specificity and regioselectivity with microsomes and purified CYP2C subfamily isozymes Journal of Toxicological Sciences. 22: 65-73. PMID 9076658 DOI: 10.2131/Jts.22.65 |
0.349 |
|
1996 |
CHO AK, JENDEN DJ. THE MECHANISM OF TREMORINE ANTAGONISM BY RELATED COMPOUNDS. International Journal of Neuropharmacology. 3: 27-36. PMID 14334594 DOI: 10.1016/0028-3908(64)90042-5 |
0.529 |
|
1996 |
Chu T, Kumagai Y, DiStefano EW, Cho AK. Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion. Biochemical Pharmacology. 51: 789-796. PMID 8602874 DOI: 10.1016/0006-2952(95)02397-6 |
0.322 |
|
1995 |
Narimatsu S, Watanabe T, Masubuchi Y, Horie T, Kumagai Y, Cho AK, Imaoka S, Funae Y, Ishikawa T, Suzuki T. Characterization of a chemically reactive propranolol metabolite that binds to microsomal proteins of rat liver. Chemical Research in Toxicology. 8: 721-728. PMID 7548755 DOI: 10.1021/Tx00047A012 |
0.354 |
|
1995 |
Narimatsu S, Arai T, Mochida M, Masubuchi Y, Horie T, Ueno K, Satoh T, Imaoka S, Funae Y, Kumagai Y, Cho AK. Interaction Of Propranolol With Cytochrome P450 -Metabolic Activation, Enzyme Inhibition And Induction- Drug Metabolism and Pharmacokinetics. 10: 146-149. DOI: 10.2133/Dmpk.10.Supplement_146 |
0.335 |
|
1994 |
Narimatsu S, Watanabe T, Mochida M, Masubuchi Y, Horie T, Imaoka S, Funae Y, Kumagai Y, Cho AK. Molecular Mechanism In Metabolic Activation Of Propranolol In Rat Liver Microsomes Drug Metabolism and Pharmacokinetics. 9: 168-171. DOI: 10.2133/Dmpk.9.Supplement_168 |
0.321 |
|
1992 |
Kumagai Y, Schmitz DA, Cho AK. Aromatic hydroxylation of methylenedioxybenzene (MDB) and methylenedioxymethamphetamine (MDMA) by rabbit liver microsomes. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 22: 395-403. PMID 1523860 DOI: 10.3109/00498259209046651 |
0.303 |
|
1992 |
Lin LY, Kumagai Y, Cho AK. Enzymatic and chemical demethylenation of (methylenedioxy)amphetamine and (methylenedioxy)methamphetamine by rat brain microsomes Chemical Research in Toxicology. 5: 401-406. PMID 1354504 DOI: 10.1021/Tx00027A013 |
0.367 |
|
1991 |
Patel N, Kumagai Y, Unger SE, Fukuto JM, Cho AK. Transformation of dopamine and α-methyldopamine by NG108-15 cells: Formation of thiol adducts Chemical Research in Toxicology. 4: 421-426. PMID 1912328 DOI: 10.1021/Tx00022A004 |
0.559 |
|
1991 |
Burstyn JN, Iskandar M, Brady JF, Fukuto JM, Cho AK. Comparative studies of N-hydroxylation and N-demethylation by microsomal cytochrome P-450. Chemical Research in Toxicology. 4: 70-6. PMID 1912302 DOI: 10.1021/Tx00019A009 |
0.531 |
|
1991 |
Cho AK, Hiramatsu M, Schmitz DA, Nabeshima T, Kameyama T. Pharmacokinetic and pharmacodynamic properties of some phencyclidine analogs in rats. Pharmacology, Biochemistry, and Behavior. 39: 947-53. PMID 1837152 DOI: 10.1016/0091-3057(91)90058-A |
0.324 |
|
1991 |
Hiramatsu M, DiStefano E, Chang AS, Cho AK. A pharmacokinetic analysis of 3,4-methylenedioxymethamphetamine effects on monoamine concentrations in brain dialysates. European Journal of Pharmacology. 204: 135-140. PMID 1725282 DOI: 10.1016/0014-2999(91)90697-O |
0.341 |
|
1991 |
Kumagai Y, Lin LY, Schmitz DA, Cho AK. Hydroxyl radical mediated demethylenation of (methylenedioxy)phenyl compounds. Chemical Research in Toxicology. 4: 330-4. PMID 1680477 DOI: 10.1021/Tx00021A012 |
0.302 |
|
1991 |
Fukuto JM, Kumagai Y, Cho AK. Determination of the mechanism of demethylenation of (methylenedioxy)phenyl compounds by cytochrome P450 using deuterium isotope effects Journal of Medicinal Chemistry. 34: 2871-2876. PMID 1680196 DOI: 10.1021/Jm00113A028 |
0.543 |
|
1991 |
Kumagai Y, Wickham KA, Schmitz DA, Cho AK. Metabolism of methylenedioxyphenyl compounds by rabbit liver preparations. Participation of different cytochrome P450 isozymes in the demethylenation reaction. Biochemical Pharmacology. 42: 1061-7. PMID 1678603 DOI: 10.1016/0006-2952(91)90289-H |
0.344 |
|
1990 |
Hiramatsu M, Cho AK. Enantiomeric differences in the effects of 3,4-methylenedioxymethamphetamine on extracellular monoamines and metabolites in the striatum of freely-moving rats: an in vivo microdialysis study. Neuropharmacology. 29: 269-275. PMID 1691459 DOI: 10.1016/0028-3908(90)90012-G |
0.346 |
|
1989 |
Gazzara RA, Takeda H, Cho AK, Howard SG. Inhibition of dopamine release by methylenedioxymethamphetamine is mediated by serotonin. European Journal of Pharmacology. 168: 209-17. PMID 2575036 DOI: 10.1016/0014-2999(89)90567-0 |
0.714 |
|
1989 |
Haak KA, Torres G, Garvey PL, Bronstein DM, Cho AK, Lytle LD. Xylamine enhances pineal gland N-acetyltransferase activity in vitro. General Pharmacology. 20: 77-80. PMID 2565274 DOI: 10.1016/0306-3623(89)90064-5 |
0.312 |
|
1989 |
Hiramatsu M, Cho AK, Toshitaka N. Comparison of the behavioral and biochemical effects of the NMDA receptor antagonists, MK-801 and phencyclidine European Journal of Pharmacology. 166: 359-366. PMID 2553433 DOI: 10.1016/0014-2999(89)90346-4 |
0.302 |
|
1986 |
Cushing SD, Howard-Butcher S, Gazzara RA, Lettes AA, Mulliez E, Cho AK. 3H-xylamine binds to presynaptic rat striatal membranes. Life Sciences. 38: 1715-21. PMID 3702601 DOI: 10.1016/0024-3205(86)90121-9 |
0.664 |
|
1986 |
Brady JF, Di Stefano EW, Cho AK. Spectral and inhibitory interactions of (+/-)-3,4-methylenedioxyamphetamine (MDA) and (+/-)-3,4-methylenedioxymethamphetamine (MDMA) with rat hepatic microsomes. Life Sciences. 39: 1457-64. PMID 2877380 DOI: 10.1016/0024-3205(86)90551-5 |
0.336 |
|
1985 |
Ransom RW, Waggaman LA, Cho AK. Interaction of xylamine with peripheral sympathetic neurons. Life Sciences. 37: 1177-1182. PMID 3930904 DOI: 10.1016/0024-3205(85)90128-6 |
0.331 |
|
1985 |
Duncan JD, Di Stefano EW, Miwa GT, Cho AK. Role of superoxide in the N-oxidation of N-(2-methyl-1-phenyl-2-propyl)hydroxylamine by the rat liver cytochrome P-450 system. Biochemistry. 24: 4155-61. PMID 2996591 DOI: 10.1021/Bi00336A051 |
0.318 |
|
1984 |
Kammerer RC, Schmitz DA, Hwa JJ, Cho AK. Induction of phencyclidine metabolism by phencyclidine, ketamine, ethanol, phenobarbital and isosafrole. Biochemical Pharmacology. 33: 599-604. PMID 6704176 DOI: 10.1016/0006-2952(84)90314-9 |
0.303 |
|
1982 |
Matsumoto RM, Cho AK. Conversion of N-hydroxyamphetamine to phenylacetone oxime by rat liver microsomes Biochemical Pharmacology. 31: 105-108. PMID 7059340 DOI: 10.1016/0006-2952(82)90244-1 |
0.347 |
|
1981 |
Kammerer RC, DiStefano E, Jonsson J, Cho AK. Metabolism of 2-nitro-1-phenylpropane by rabbit liver microsomes Biochemical Pharmacology. 30: 2257-2263. PMID 7295340 DOI: 10.1016/0006-2952(81)90096-4 |
0.307 |
|
1981 |
Rapoport RM, Takimoto GS, Cho AK. Compartmental analysis of tyramine-induced norepinephrine depletion. Pharmacology. 22: 235-42. PMID 7267695 DOI: 10.1159/000137495 |
0.3 |
|
1981 |
Maynard MS, Cho AK. Oxidation of N-hydroxyphentermine to 2-methyl-2-nitro-1-phenylpropane by liver microsomes. Biochemical Pharmacology. 30: 1115-1119. PMID 6894858 DOI: 10.1016/0006-2952(81)90450-0 |
0.32 |
|
1979 |
Goldberg MA, Gal J, Cho AK, Jenden DJ. Metabolism of dimethoxymethyl phenobarbital (eterobarb) in patients with epilepsy. Annals of Neurology. 5: 121-6. PMID 426475 DOI: 10.1002/Ana.410050205 |
0.517 |
|
1979 |
Jenden DJ, Cho AK. Selected ion monitoring in pharmacology. Biochemical Pharmacology. 28: 705-13. PMID 378237 DOI: 10.1016/0006-2952(79)90345-9 |
0.459 |
|
1978 |
May PR, Van Putten T, Jenden DJ, Cho AK. Test dose response in schizophrenia: chlorpromazine blood and saliva levels. Archives of General Psychiatry. 35: 1091-7. PMID 686971 DOI: 10.1001/Archpsyc.1978.01770330065005 |
0.502 |
|
1977 |
Cho AK, Fischer JF, Schaeffer JC. The accumulation of p-hydroxyamphetamine by brain homogenates and its role in the release of catecholamines Biochemical Pharmacology. 26: 1367-1372. PMID 901551 DOI: 10.1016/0006-2952(77)90358-6 |
0.312 |
|
1976 |
Carson VG, Jenden DJ, Cho AK, Green R. Effects of the choline acetyltransferase inhibitor 3'choloro-4-stilbazole on brain acetylcholine metabolism. Biochemical Pharmacology. 25: 195-9. PMID 1259780 DOI: 10.1016/0006-2952(76)90290-2 |
0.531 |
|
1975 |
Cho AK, Hodshon BJ, Lindeke B, Jonsson J. The p-Hydroxylation of Amphetamine and Phentermine by Rat Liver Microsomes Xenobiotica. 5: 531-538. PMID 242122 DOI: 10.3109/00498257509056123 |
0.353 |
|
1973 |
Cho AK, Hodshon BJ, Lindeke B, Miwa GT. Application of Quantitative GC–Mass Spectrometry to Study of Pharmacokinetics of Amphetamine and Phentermine Journal of Pharmaceutical Sciences. 62: 1491-1494. PMID 4743099 DOI: 10.1002/Jps.2600620922 |
0.304 |
|
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