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Stephen Mills - Publications

Affiliations: 
Pharmacology University of Oxford, Oxford, United Kingdom 
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Su X, Dohle W, Mills SJ, Watt JM, Rossi AM, Taylor CW, Potter BVL. Inositol Adenophostin: Convergent Synthesis of a Potent Agonist of d--Inositol 1,4,5-Trisphosphate Receptors. Acs Omega. 5: 28793-28811. PMID 33195933 DOI: 10.1021/acsomega.0c04145  0.698
2020 Mills SJ, Rossi AM, Konieczny V, Bakowski D, Taylor CW, Potter BVL. D-chiro-Inositol Ribophostin: a Highly Potent Agonist at D-myo-Inositol 1,4,5-Trisphosphate Receptors: Synthesis and Biological Activities. Journal of Medicinal Chemistry. PMID 32052631 DOI: 10.1021/Acs.Jmedchem.9B01986  0.467
2019 Dohle W, Su X, Mills SJ, Rossi AM, Taylor CW, Potter BVL. A synthetic cyclitol-nucleoside conjugate polyphosphate is a highly potent second messenger mimic. Chemical Science. 10: 5382-5390. PMID 31171961 DOI: 10.1039/C9Sc00445A  0.396
2016 Mills SJ, Silvander C, Cozier GE, Tresaugues L, Nordlund P, Potter BV. Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase INPP5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family. Biochemistry. PMID 26854536 DOI: 10.1021/Acs.Biochem.5B00838  0.53
2015 Thomas MP, Mills SJ, Potter BV. The "Other" Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo-Inositol Chemistry). Angewandte Chemie (International Ed. in English). PMID 26694856 DOI: 10.1002/Anie.201502227  0.513
2015 Swarbrick JM, Riley AM, Mills SJ, Potter BVL. Designer small molecules to target calcium signalling Biochemical Society Transactions. 43: 417-425. PMID 26009185 DOI: 10.1042/Bst20140293  0.355
2012 Mills SJ, Luyten T, Erneux C, Parys JB, Potter BV. Multivalent benzene polyphosphate derivatives are non-Ca(2+)-mobilizing Ins(1,4,5)P3 receptor antagonists. Messenger (Los Angeles, Calif. : Print). 1: 167-181. PMID 24749014 DOI: 10.1166/Msr.2012.1016  0.597
2012 Grint T, Riley AM, Mills SJ, Potter BV, Safrany ST. Fibrinogen - a possible extracellular target for inositol phosphates. Messenger (Los Angeles, Calif. : Print). 1: 160-166. PMID 24749013 DOI: 10.1166/Msr.2012.1014  0.47
2012 Mills SJ, Persson C, Cozier G, Thomas MP, Trésaugues L, Erneux C, Riley AM, Nordlund P, Potter BV. A synthetic polyphosphoinositide headgroup surrogate in complex with SHIP2 provides a rationale for drug discovery. Acs Chemical Biology. 7: 822-8. PMID 22330088 DOI: 10.1021/Cb200494D  0.498
2010 MILLS SJ, RILEY AM, MURPHY CT, BULLOCK AJ, WESTWICK J, POTTER BVL. ChemInform Abstract: myo-Inositol 1,4,6-Trisphosphorothioate and myo-Inositol 1,3,4- Trisphosphorothioate: New Synthetic Ca2+-Mobilizing Partial Agonists at the Inositol 1,4,5-Trisphosphate Receptor. Cheminform. 26: no-no. DOI: 10.1002/chin.199527256  0.302
2007 Vandeput F, Combettes L, Mills SJ, Backers K, Wohlkönig A, Parys JB, De Smedt H, Missiaen L, Dupont G, Potter BV, Erneux C. Biphenyl 2,3',4,5',6-pentakisphosphate, a novel inositol polyphosphate surrogate, modulates Ca2+ responses in rat hepatocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1481-91. PMID 17264160 DOI: 10.1096/Fj.06-7691Com  0.59
2006 Mills SJ, Dozol H, Vandeput F, Backers K, Woodman T, Erneux C, Spiess B, Potter BV. 3-hydroxybenzene 1,2,4-trisphosphate, a novel second messenger mimic and unusual substrate for type-I myo-inositol 1,4,5-trisphosphate 5-phosphatase: Synthesis and physicochemistry. Chembiochem : a European Journal of Chemical Biology. 7: 1696-706. PMID 16964627 DOI: 10.1002/Cbic.200600125  0.467
2005 Poinas A, Backers K, Riley AM, Mills SJ, Moreau C, Potter BV, Erneux C. Interaction of the catalytic domain of inositol 1,4,5-trisphosphate 3-kinase A with inositol phosphate analogues. Chembiochem : a European Journal of Chemical Biology. 6: 1449-57. PMID 15997461 DOI: 10.1002/Cbic.200400443  0.558
2004 Kunerth S, Langhorst MF, Schwarzmann N, Gu X, Huang L, Yang Z, Zhang L, Mills SJ, Zhang LH, Potter BV, Guse AH. Amplification and propagation of pacemaker Ca2+ signals by cyclic ADP-ribose and the type 3 ryanodine receptor in T cells. Journal of Cell Science. 117: 2141-9. PMID 15054112 DOI: 10.1242/Jcs.01063  0.492
2004 Horne G, Mills SJ, Potter BV. First derivatives of myo-inositol 1,4,6-trisphosphate modified at positions 2 and 3: structural analogues of D-myo-inositol 1,4,5-trisphosphate. Carbohydrate Research. 339: 51-65. PMID 14659671 DOI: 10.1016/J.Carres.2003.09.008  0.453
2003 Mills SJ, Riley AM, Liu C, Mahon MF, Potter BV. A definitive synthesis of D-myo-inositol 1,4,5,6-tetrakisphosphate and its enantiomer D-myo-inositol 3,4,5,6-tetrakisphosphate from a novel butane-2,3-diacetal-protected inositol. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 6207-14. PMID 14679531 DOI: 10.1002/CHIN.200413165  0.521
2003 Mills SJ, Backers K, Erneux C, Potter BV. Synthesis of D- and L-myo-inositol 1,2,4,6-tetrakisphosphate, regioisomers of myo-inositol 1,3,4,5 tetrakisphosphate: activity against Ins(1,4,5)P3 binding proteins. Organic & Biomolecular Chemistry. 1: 3546-56. PMID 14599016 DOI: 10.1039/B302986G  0.58
2003 Mills SJ, Potter BV. Synthesis of potent Ins(1,4,5)P3 5-phosphatase inhibitors by modification of myo-inositol 1,3,4,6-tetrakisphosphate. Bioorganic & Medicinal Chemistry. 11: 4245-53. PMID 12951155 DOI: 10.1016/S0968-0896(03)00347-X  0.58
2003 Mills SJ, Backers K, Erneux C, Potter BVL. Synthesis of D- and L-myo-inositol 1,2,4,6-tetrakisphosphate, regioisomers of myo-inositol 1,3,4,5 tetrakisphosphate: Activity against Ins(1,4,5)P 3 binding proteins Organic and Biomolecular Chemistry. 1: 3546-3556. DOI: 10.1039/b302986g  0.397
2002 Mills SJ, Liu C, Potter BV. Synthesis of D- and L-myo-inositol 2,4,5-trisphosphate and trisphosphorothioate: structural analogues of D-myo-inositol 1,4,5-trisphosphate. Carbohydrate Research. 337: 1795-801. PMID 12431881 DOI: 10.1016/S0008-6215(02)00289-6  0.537
2001 Ukhanov K, Mills SJ, Potter BV, Walz B. InsP(3)-induced Ca(2+) release in permeabilized invertebrate photoreceptors: a link between phototransduction and Ca(2+) stores. Cell Calcium. 29: 335-45. PMID 11292390 DOI: 10.1054/Ceca.2001.0195  0.54
2000 Murphy CT, Riley AM, Mills SJ, Lindley CJ, Potter BV, Westwick J. myo-inositol 1,4,6-trisphosphorothioate and myo-inositol 1,3, 6-trisphosphorothioate: partial agonists with very low intrinsic activity at the platelet myo-inositol 1,4,5-trisphosphate receptor. Molecular Pharmacology. 57: 595-601. PMID 10692501 DOI: 10.1124/Mol.57.3.595  0.602
1999 Hirst PH, Riley AM, Mills SJ, Spiers ID, Poyner DR, Freeman S, Potter BV, Smith AW. Inositol polyphosphate-mediated iron transport in Pseudomonas aeruginosa. Journal of Applied Microbiology. 86: 537-43. PMID 10196759 DOI: 10.1046/J.1365-2672.1999.00697.X  0.425
1997 Hirata M, Takeuchi H, Riley AM, Mills SJ, Watanabe Y, Potter BV. Inositol 1,4,5-trisphosphate receptor subtypes differentially recognize regioisomers of D-myo-inositol 1,4,5-trisphosphate. The Biochemical Journal. 328: 93-8. PMID 9359838  0.549
1996 Mills SJ, Potter BV. Synthesis of D- and L-myo-Inositol 1,4,6-Trisphosphate, Regioisomers of a Ubiquitous Second Messenger. The Journal of Organic Chemistry. 61: 8980-8987. PMID 11667881 DOI: 10.1021/Jo961280X  0.585
1996 Mills S, Potter B. The Synthesis of Chiral Myo-Inositol Trisphosphate Analogues Phosphorus, Sulfur, and Silicon and the Related Elements. 111: 72-72. DOI: 10.1080/10426509608054701  0.602
1996 Riley A, Mills S, Potter B. Long-Range 31P-31P Spin Coupling Constants in the 31P NMR Spectra of Phosphite Triesters Phosphorus, Sulfur, and Silicon and the Related Elements. 111: 71-71. DOI: 10.1080/10426509608054700  0.434
1996 Mills SJ, Potter BVL. Synthesis of D- and L-myo-inositol 1,4,6-trisphosphate, regioisomers of a ubiquitous second messenger Journal of Organic Chemistry. 61: 8980-8987. DOI: 10.1021/jo961280x  0.409
1995 Ward SG, Mills SJ, Liu C, Westwick J, Potter BV. D-myo-inositol 1,4,5-trisphosphate analogues modified at the 3-position inhibit phosphatidylinositol 3-kinase. The Journal of Biological Chemistry. 270: 12075-84. PMID 7744856 DOI: 10.1074/Jbc.270.20.12075  0.578
1995 Mills SJ, Riley AM, Murphy CT, Bullock AJ, Westwick J, Potter BV. Myo-inositol 1,4,6-trisphosphorothioate and myo-inositol 1,3,4-trisphosphorothioate: New synthetic Ca2+-mobilising partial agonists at the inositol 1,4,5-trisphosphate receptor Bioorganic and Medicinal Chemistry Letters. 5: 203-208. DOI: 10.1016/0960-894X(95)00012-I  0.553
1994 Safrany ST, Mills SJ, Liu C, Lampe D, Noble NJ, Nahorski SR, Potter BV. Design of potent and selective inhibitors of myo-inositol 1,4,5-trisphosphate 5-phosphatase. Biochemistry. 33: 10763-9. PMID 8075077 DOI: 10.1021/Bi00201A025  0.545
1994 Wilcox RA, Safrany ST, Lampe D, Mills SJ, Nahorski SR, Potter BV. Modification at C2 of myo-inositol 1,4,5-trisphosphate produces inositol trisphosphates and tetrakisphosphates with potent biological activities. European Journal of Biochemistry / Febs. 223: 115-24. PMID 8033885 DOI: 10.1111/J.1432-1033.1994.Tb18972.X  0.573
1993 Mills SJ, Al-Hafidh J, Westwick J, Potter BVL. Myo-inositol 1,4,6-trisphosphate: A new synthetic Ca2+-mobilising inositol phosphate Bioorganic and Medicinal Chemistry Letters. 3: 2599-2604. DOI: 10.1016/S0960-894X(01)80723-X  0.403
1993 Mills SJ, Safrany ST, Wilcox RA, Nahorski SR, Potter BV. Synthesis of myo-inositol 1,2,4,5-tetrakisphosphate, a Ca2+-mobilising tetrakisphosphate with a potency similar to myo-inositol 1,4,5-trisphosphate Bioorganic and Medicinal Chemistry Letters. 3: 1505-1510. DOI: 10.1016/S0960-894X(00)80007-4  0.572
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