Derek Macmillan - Publications

Affiliations: 
Chemistry University College London, London, United Kingdom 

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Nyandoro K, Lamb CMG, Yu H, Shi J, Macmillan D. Investigation of acyl transfer auxiliary-assisted glycoconjugation for glycoprotein semi-synthesis. Organic & Biomolecular Chemistry. PMID 36278418 DOI: 10.1039/d2ob01633h  0.444
2022 Lamb CMG, Shi J, Wilden JD, Macmillan D. Novel electrochemically-mediated peptide dethiylation in processes relevant to native chemical ligation. Organic & Biomolecular Chemistry. PMID 36073340 DOI: 10.1039/d2ob01499h  0.401
2021 Barnes NG, Nyandoro K, Jin H, Macmillan D. Rapid access to Asp/Glu sidechain hydrazides as thioester precursors for peptide cyclization and glycosylation. Chemical Communications (Cambridge, England). PMID 33399597 DOI: 10.1039/d0cc07404g  0.425
2017 Gibson SM, Macmillan D, Sheppard TD. Synthesis of Boronocysteine Synlett. 29: 314-317. DOI: 10.1055/S-0036-1591491  0.343
2017 Castillo-Pazos DJ, Macmillan D. Investigation of Cysteine as an Activator of Side-Chain N→S Acyl Transfer and Tail-to-Side-Chain Cyclization Synlett. 28: 1923-1928. DOI: 10.1055/S-0036-1590797  0.451
2017 Macmillan D. Going Round in Circles with N -> S Acyl Transfer Synlett. 28: 1517-1529. DOI: 10.1055/S-0036-1588789  0.587
2016 Chen W, Kinsler VA, Macmillan D, Di WL. Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold - A Potential Therapeutic Intervention for Skin Diseases. Plos One. 11: e0166268. PMID 27824929 DOI: 10.1371/Journal.Pone.0166268  0.307
2015 Cowper B, Shariff L, Chen W, Gibson SM, Di WL, Macmillan D. Expanding the scope of N → S acyl transfer in native peptide sequences. Organic & Biomolecular Chemistry. PMID 26066020 DOI: 10.1039/C5Ob01029B  0.532
2015 Cowper B, Sze TM, Premdjee B, Bongat White AF, Hacking A, Macmillan D. Examination of mercaptobenzyl sulfonates as catalysts for native chemical ligation: application to the assembly of a glycosylated Glucagon-Like Peptide 1 (GLP-1) analogue. Chemical Communications (Cambridge, England). 51: 3208-10. PMID 25605668 DOI: 10.1039/C4Cc09502B  0.707
2013 Adams AL, Cowper B, Morgan RE, Premdjee B, Caddick S, Macmillan D. Cysteine promoted C-terminal hydrazinolysis of native peptides and proteins. Angewandte Chemie (International Ed. in English). 52: 13062-6. PMID 24123371 DOI: 10.1002/Anie.201304997  0.75
2013 Currie SM, Findlay EG, McHugh BJ, Mackellar A, Man T, Macmillan D, Wang H, Fitch PM, Schwarze J, Davidson DJ. The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus. Plos One. 8: e73659. PMID 24023689 DOI: 10.1371/Journal.Pone.0073659  0.301
2013 Cowper B, Craik DJ, Macmillan D. Making ends meet: chemically mediated circularization of recombinant proteins. Chembiochem : a European Journal of Chemical Biology. 14: 809-12. PMID 23559418 DOI: 10.1002/Cbic.201300105  0.569
2013 Adams AL, Macmillan D. Investigation of peptide thioester formation via N→Se acyl transfer Journal of Peptide Science. 19: 65-73. PMID 23297044 DOI: 10.1002/Psc.2469  0.584
2012 Harvey SR, Porrini M, Stachl C, MacMillan D, Zinzalla G, Barran PE. Small-molecule inhibition of c-MYC:MAX leucine zipper formation is revealed by ion mobility mass spectrometry. Journal of the American Chemical Society. 134: 19384-92. PMID 23106332 DOI: 10.1021/Ja306519H  0.305
2011 Macmillan D, Adams A, Premdjee B. Shifting Native Chemical Ligation into Reverse through N→S Acyl Transfer. Israel Journal of Chemistry. 51: 885-899. PMID 22347724 DOI: 10.1002/Ijch.201100084  0.747
2011 Macmillan D, de Cecco M, Reynolds NL, Santos LFA, Barran PE, Dorin JR. Synthesis of cyclic peptides through an intramolecular amide bond rearrangement Chembiochem. 12: 2133-2136. PMID 21805553 DOI: 10.1002/Cbic.201100364  0.489
2011 Premdjee B, Adams AL, Macmillan D. Native N-glycopeptide thioester synthesis through N→S acyl transfer. Bioorganic & Medicinal Chemistry Letters. 21: 4973-5. PMID 21676613 DOI: 10.1016/J.Bmcl.2011.05.059  0.749
2011 Richardson JP, Macmillan D. Semi-synthesis of glycoproteins from E. coli through native chemical ligation. Methods in Molecular Biology (Clifton, N.J.). 705: 151-74. PMID 21125385 DOI: 10.1007/978-1-61737-967-3_9  0.516
2011 Hirano K, Izumi M, Macmillan D, Tezuka K, Tsuji T, Kajihara Y. Semisynthesis of Erythropoietin Analog Having Three Oligosaccharides Journal of Carbohydrate Chemistry. 30: 306-319. DOI: 10.1080/07328303.2011.604570  0.464
2011 Kajihara Y, Izumi M, Hirano K, Murase T, Macmillan D, Okamoto R. Elucidating the Function of Complex‐Type Oligosaccharides by Use of Chemical Synthesis of Homogeneous Glycoproteins Israel Journal of Chemistry. 51: 917-929. DOI: 10.1002/Ijch.201100081  0.527
2010 Masania J, Li J, Smerdon SJ, Macmillan D. Access to phosphoproteins and glycoproteins through semi-synthesis, Native Chemical Ligation and N→S acyl transfer. Organic & Biomolecular Chemistry. 8: 5113-9. PMID 20835458 DOI: 10.1039/C0Ob00363H  0.584
2010 Ackrill T, Anderson DW, Macmillan D. Towards biomolecular assembly employing extended native chemical ligation in combination with thioester synthesis using an N-->S acyl shift. Biopolymers. 94: 495-503. PMID 20593460 DOI: 10.1002/Bip.21473  0.528
2010 Kang J, Macmillan D. Peptide and protein thioester synthesis via N-->S acyl transfer. Organic & Biomolecular Chemistry. 8: 1993-2002. PMID 20401371 DOI: 10.1039/B925075A  0.632
2010 Virdee S, Macmillan D, Waksman G. Semisynthetic Src SH2 domains demonstrate altered phosphopeptide specificity induced by incorporation of unnatural lysine derivatives. Chemistry & Biology. 17: 274-84. PMID 20338519 DOI: 10.1016/J.Chembiol.2010.01.015  0.313
2010 McCullough BJ, Kalapothakis JM, Chin W, Taylor K, Clarke DJ, Eastwood H, Campopiano D, MacMillan D, Dorin J, Barran PE. Binding a heparin derived disaccharide to defensin inspired peptides: insights to antimicrobial inhibition from gas-phase measurements. Physical Chemistry Chemical Physics : Pccp. 12: 3589-96. PMID 20336257 DOI: 10.1039/B923784D  0.485
2010 Richardson JP, Chan CH, Blanc J, Saadi M, Macmillan D. Exploring neoglycoprotein assembly through native chemical ligation using neoglycopeptide thioesters prepared via N-->S acyl transfer. Organic & Biomolecular Chemistry. 8: 1351-60. PMID 20204207 DOI: 10.1039/B920535G  0.447
2010 Reynolds NL, De Cecco M, Taylor K, Stanton C, Kilanowski F, Kalapothakis J, Seo E, Uhrin D, Campopiano D, Govan J, Macmillan D, Barran P, Dorin JR. Peptide fragments of a β-defensin derivative with potent bactericidal activity Antimicrobial Agents and Chemotherapy. 54: 1922-1929. PMID 20176896 DOI: 10.1128/Aac.01568-09  0.503
2010 De Cecco M, Seo ES, Clarke DJ, McCullough BJ, Taylor K, Macmillan D, Dorin JR, Campopiano DJ, Barran PE. Conformational preferences of linear beta-defensins are revealed by ion mobility-mass spectrometry. The Journal of Physical Chemistry. B. 114: 2312-8. PMID 20102218 DOI: 10.1021/Jp9111662  0.42
2010 Tyrrell C, De Cecco M, Reynolds NL, Kilanowski F, Campopiano D, Barran P, Macmillan D, Dorin JR. Isoleucine/leucine2 is essential for chemoattractant activity of β-defensin Defb14 through chemokine receptor 6 Molecular Immunology. 47: 1378-1382. PMID 20022113 DOI: 10.1016/J.Molimm.2009.11.025  0.436
2009 Kang J, Reynolds NL, Tyrrell C, Dorin JR, MacMillan D. Peptide thioester synthesis through N→S acyl-transfer: Application to the synthesis of a β-defensin Organic and Biomolecular Chemistry. 7: 4918-4923. PMID 19907782 DOI: 10.1039/B913886B  0.613
2009 Hirano K, Macmillan D, Tezuka K, Tsuji T, Kajihara Y. Design and synthesis of a homogeneous erythropoietin analogue with two human complex-type sialyloligosaccharides: combined use of chemical and bacterial protein expression methods. Angewandte Chemie (International Ed. in English). 48: 9557-60. PMID 19798711 DOI: 10.1002/Anie.200904376  0.38
2009 Taylor K, Rolfe M, Reynolds N, Kilanowski F, Pathania U, Clarke D, Yang D, Oppenheim J, Samuel K, Howie S, Barran P, Macmillan D, Campopiano D, Dorin J. Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6. European Journal of Immunology. 39: 1353-60. PMID 19404978 DOI: 10.1002/Eji.200838566  0.393
2009 Kang J, Richardson JP, Macmillan D. 3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters. Chemical Communications (Cambridge, England). 407-9. PMID 19137167 DOI: 10.1039/B815888F  0.587
2009 Hirano K, Macmillan D, Tezuka K, Tsuji T, Kajihara Y. Innentitelbild: Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex‐Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods (Angew. Chem. 50/2009) Angewandte Chemie. 121: 9542-9542. DOI: 10.1002/Ange.200905761  0.393
2008 Richardson JP, Macmillan D. Optimisation of chemical protein cleavage for erythropoietin semi-synthesis using native chemical ligation. Organic & Biomolecular Chemistry. 6: 3977-82. PMID 18931805 DOI: 10.1039/B811501J  0.506
2008 McCullough BJ, Kalapothakis J, Eastwood H, Kemper P, MacMillan D, Taylor K, Dorin J, Barran PE. Development of an ion mobility quadrupole time of flight mass spectrometer. Analytical Chemistry. 80: 6336-44. PMID 18627133 DOI: 10.1021/Ac800651B  0.365
2008 Taylor K, Clarke DJ, McCullough B, Chin W, Seo E, Yang D, Oppenheim J, Uhrin D, Govan JR, Campopiano DJ, MacMillan D, Barran P, Dorin JR. Analysis and separation of residues important for the chemoattractant and antimicrobial activities of beta-defensin 3. The Journal of Biological Chemistry. 283: 6631-9. PMID 18180295 DOI: 10.1074/Jbc.M709238200  0.478
2006 Macmillan D. Evolving strategies for protein synthesis converge on native chemical ligation. Angewandte Chemie (International Ed. in English). 45: 7668-72. PMID 17091510 DOI: 10.1002/Anie.200602945  0.456
2006 Macmillan D, Blanc J. A novel neoglycopeptide linkage compatible with native chemical ligation. Organic & Biomolecular Chemistry. 4: 2847-50. PMID 16855731 DOI: 10.1039/B607200C  0.544
2004 Macmillan D, Anderson DW. Rapid synthesis of acyl transfer auxiliaries for cysteine-free native glycopeptide ligation. Organic Letters. 6: 4659-62. PMID 15575654 DOI: 10.1021/Ol048145O  0.536
2004 Macmillan D, Bertozzi CR. Modular assembly of glycoproteins: towards the synthesis of GlyCAM-1 by using expressed protein ligation. Angewandte Chemie (International Ed. in English). 43: 1355-9. PMID 15368405 DOI: 10.1002/Anie.200352673  0.539
2004 Macmillan D, Arham L. Cyanogen bromide cleavage generates fragments suitable for expressed protein and glycoprotein ligation. Journal of the American Chemical Society. 126: 9530-1. PMID 15291543 DOI: 10.1021/Ja047855M  0.528
2003 Macmillan D, Daines AM. Recent developments in the synthesis and discovery of oligosaccharides and glycoconjugates for the treatment of disease. Current Medicinal Chemistry. 10: 2733-73. PMID 14529463 DOI: 10.2174/0929867033456413  0.343
2002 Macmillan D, Daines AM, Bayrhuber M, Flitsch SL. Solid-phase synthesis of thioether-linked glycopeptide mimics for application to glycoprotein semisynthesis. Organic Letters. 4: 1467-70. PMID 11975605 DOI: 10.1021/Ol025627W  0.42
2001 Macmillan D, Bill RM, Sage KA, Fern D, Flitsch SL. Selective in vitro glycosylation of recombinant proteins: semi-synthesis of novel homogeneous glycoforms of human erythropoietin. Chemistry & Biology. 8: 133-45. PMID 11251288 DOI: 10.1016/S1074-5521(00)90065-6  0.436
2000 Macmillan D, Bertozzi CR. New Directions in Glycoprotein Engineering Tetrahedron. 56: 9515-9525. DOI: 10.1016/S0040-4020(00)00836-X  0.59
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