Year |
Citation |
Score |
2022 |
Boland S, Swarup S, Ambaw YA, Malia PC, Richards RC, Fischer AW, Singh S, Aggarwal G, Spina S, Nana AL, Grinberg LT, Seeley WW, Surma MA, Klose C, Paulo JA, ... Nguyen AD, et al. Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis. Nature Communications. 13: 5924. PMID 36207292 DOI: 10.1038/s41467-022-33500-9 |
0.619 |
|
2018 |
Nguyen AD, Nguyen TA, Singh RK, Eberlé D, Zhang J, Abate JP, Robles A, Koliwad S, Huang EJ, Maxfield FR, Walther TC, Farese RV. Progranulin in the hematopoietic compartment protects mice from atherosclerosis. Atherosclerosis. 277: 145-154. PMID 30212683 DOI: 10.1016/J.Atherosclerosis.2018.08.042 |
0.578 |
|
2018 |
Nguyen AD, Nguyen TA, Zhang J, Devireddy S, Zhou P, Karydas AM, Xu X, Miller BL, Rigo F, Ferguson SM, Huang EJ, Walther TC, Farese RV. Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay. Proceedings of the National Academy of Sciences of the United States of America. PMID 29511098 DOI: 10.1073/Pnas.1722344115 |
0.612 |
|
2017 |
Hwang S, Nguyen AD, Jo Y, Engelking LJ, Brugarolas J, DeBose-Boyd RA. Hypoxia-inducible factor-1α activates insig-2 transcription for degradation of HMG CoA reductase in the liver. The Journal of Biological Chemistry. PMID 28416613 DOI: 10.1074/Jbc.M117.788562 |
0.628 |
|
2013 |
Nguyen AD, Nguyen TA, Martens LH, Mitic LL, Farese RV. Progranulin: at the interface of neurodegenerative and metabolic diseases. Trends in Endocrinology and Metabolism: Tem. 24: 597-606. PMID 24035620 DOI: 10.1016/j.tem.2013.08.003 |
0.41 |
|
2013 |
Faulkner RA, Nguyen AD, Jo Y, DeBose-Boyd RA. Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells. Journal of Lipid Research. 54: 1011-22. PMID 23403031 DOI: 10.1194/Jlr.M033639 |
0.651 |
|
2013 |
Nguyen AD, Nguyen TA, Cenik B, Yu G, Herz J, Walther TC, Davidson WS, Farese RV. Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL). The Journal of Biological Chemistry. 288: 8627-35. PMID 23364791 DOI: 10.1074/Jbc.M112.441949 |
0.601 |
|
2009 |
Nguyen AD, Lee SH, DeBose-Boyd RA. Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cells. The Journal of Biological Chemistry. 284: 26778-88. PMID 19638338 DOI: 10.1074/jbc.M109.032342 |
0.645 |
|
2007 |
Nguyen AD, McDonald JG, Bruick RK, DeBose-Boyd RA. Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs. The Journal of Biological Chemistry. 282: 27436-46. PMID 17635920 DOI: 10.1074/Jbc.M704976200 |
0.629 |
|
2007 |
Lee PC, Nguyen AD, Debose-Boyd RA. Mutations within the membrane domain of HMG-CoA reductase confer resistance to sterol-accelerated degradation. Journal of Lipid Research. 48: 318-27. PMID 17090658 DOI: 10.1194/jlr.M600476-JLR200 |
0.642 |
|
1999 |
Krappa R, Nguyen A, Burrola P, Deretic D, Lemke G. Evectins: vesicular proteins that carry a pleckstrin homology domain and localize to post-Golgi membranes. Proceedings of the National Academy of Sciences of the United States of America. 96: 4633-4638. PMID 10200314 DOI: 10.1073/Pnas.96.8.4633 |
0.367 |
|
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