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John J. Rossi - Publications

Affiliations: 
Molecular and Cellular Biology  Beckman Research Institute of the City of Hope 
Area:
RNA biology
Website:
https://www.cityofhope.org/people/rossi-john
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370 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chinnapaiyan S, Santiago MJ, Panda K, Rahman MS, Alluin J, Rossi J, Unwalla HJ. A conditional RNA Pol II mono-promoter drives HIV-inducible, CRISPR-mediated cyclin T1 suppression and HIV inhibition. Molecular Therapy. Nucleic Acids. 32: 553-565. PMID 37215150 DOI: 10.1016/j.omtn.2023.04.011  0.38
2022 Song MS, Alluin J, Rossi JJ. The Effect of Dicer Knockout on RNA Interference Using Various Dicer Substrate Small Interfering RNA (DsiRNA) Structures. Genes. 13. PMID 35327991 DOI: 10.3390/genes13030436  0.369
2021 Miele D, Xia X, Catenacci L, Sorrenti M, Rossi S, Sandri G, Ferrari F, Rossi JJ, Bonferoni MC. Chitosan Oleate Coated PLGA Nanoparticles as siRNA Drug Delivery System. Pharmaceutics. 13. PMID 34684009 DOI: 10.3390/pharmaceutics13101716  0.315
2021 Setten RL, Chomchan P, Epps EW, Burnett JC, Rossi JJ. CRED9: A differentially expressed elncRNA regulates expression of transcription factor CEBPA. Rna (New York, N.Y.). PMID 34039742 DOI: 10.1261/rna.078752.121  0.513
2020 Sarker D, Plummer R, Meyer T, Sodergren M, Basu B, Chee CE, Huang KW, Palmer DH, Ma YT, Evans TRJ, Spalding DR, Pai M, Sharma R, Pinato DJ, Spicer J, ... ... Rossi JJ, et al. MTL-CEBPA, a small activating RNA therapeutic up-regulating C/EBP-α, in patients with advanced liver cancer: a first-in-human, multi-centre, open-label, phase I trial. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32357963 DOI: 10.1158/1078-0432.Ccr-20-0414  0.345
2020 Habibian M, Harikrishna S, Fakhoury J, Barton M, Ageely EA, Cencic R, Fakih HH, Katolik A, Takahashi M, Rossi J, Pelletier J, Gagnon KT, Pradeepkumar PI, Damha MJ. Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference. Nucleic Acids Research. PMID 32282904 DOI: 10.1093/Nar/Gkaa222  0.389
2020 Bowman N, Liu D, Paczkowski P, Chen J, Rossi J, Mackay S, Bot A, Zhou J. Advanced Cell Mapping Visualizations for Single Cell Functional Proteomics Enabling Patient Stratification. Proteomics. e1900270. PMID 32108428 DOI: 10.1002/Pmic.201900270  0.322
2019 Yoon S, Huang KW, Andrikakou P, Vasconcelos D, Swiderski P, Reebye V, Sodergren M, Habib N, Rossi JJ. Targeted Delivery of C/EBPα-saRNA by RNA Aptamers Shows Anti-tumor Effects in a Mouse Model of Advanced PDAC. Molecular Therapy. Nucleic Acids. 18: 142-154. PMID 31546149 DOI: 10.1016/J.Omtn.2019.08.017  0.363
2019 Xia X, Pollock N, Zhou J, Rossi J. Tissue-Specific Delivery of Oligonucleotides. Methods in Molecular Biology (Clifton, N.J.). 2036: 17-50. PMID 31410789 DOI: 10.1007/978-1-4939-9670-4_2  0.353
2019 Takahashi M, Li H, Zhou J, Chomchan P, Aishwarya V, Damha MJ, Rossi JJ. Dual Mechanisms of Action of Self-Delivering, Anti-HIV-1 FANA Oligonucleotides as a Potential New Approach to HIV Therapy. Molecular Therapy. Nucleic Acids. 17: 615-625. PMID 31394430 DOI: 10.1016/J.Omtn.2019.07.001  0.483
2019 Arizala JAC, Chomchan P, Li H, Moore R, Ge H, Ouellet DL, Rossi JJ. Identification of Nucleolar Factors During HIV-1 Replication Through Rev Immunoprecipitation and Mass Spectrometry. Journal of Visualized Experiments : Jove. PMID 31305524 DOI: 10.3791/59329  0.407
2019 Xia X, Zhou Z, DeSantis C, Rossi JJ, Bong D. Triplex hybridization of siRNA with bifacial glycopolymer nucleic acid enables hepatocyte-targeted silencing. Acs Chemical Biology. PMID 31141333 DOI: 10.1021/Acschembio.9B00273  0.38
2019 Setten RL, Rossi JJ, Han SP. The current state and future directions of RNAi-based therapeutics. Nature Reviews. Drug Discovery. 18: 421-446. PMID 30846871 DOI: 10.1038/S41573-019-0017-4  0.411
2019 Xia X, Li H, Satheesan S, Zhou J, Rossi JJ. Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies. Journal of Visualized Experiments : Jove. PMID 30663638 DOI: 10.3791/58255  0.336
2019 Zhao X, Reebye V, Hitchen P, Fan J, Jiang H, Sætrom P, Rossi J, Habib NA, Huang KW. Mechanisms involved in the activation of C/EBPα by small activating RNA in hepatocellular carcinoma. Oncogene. PMID 30643190 DOI: 10.1038/S41388-018-0665-6  0.338
2018 Yoon S, Wu X, Armstrong B, Habib N, Rossi JJ. An RNA Aptamer Targeting the Receptor Tyrosine Kinase PDGFRα Induces Anti-tumor Effects through STAT3 and p53 in Glioblastoma. Molecular Therapy. Nucleic Acids. 14: 131-141. PMID 30594071 DOI: 10.1016/J.Omtn.2018.11.012  0.411
2018 Yoon S, Rossi JJ. Aptamers: Uptake mechanisms and intracellular applications. Advanced Drug Delivery Reviews. PMID 29981799 DOI: 10.1016/J.Addr.2018.07.003  0.37
2018 Setten RL, Lightfoot HL, Habib NA, Rossi JJ. Development of MTL-CEBPA: Small Activating RNA Drug for Hepatocellular Carcinoma. Current Pharmaceutical Biotechnology. 19: 611-621. PMID 29886828 DOI: 10.2174/1389201019666180611093428  0.404
2018 Yoon S, Rossi JJ. Therapeutic Potential of Small Activating RNAs (saRNAs) in Human cancers. Current Pharmaceutical Biotechnology. PMID 29804529 DOI: 10.2174/1389201019666180528084059  0.429
2018 Arizala JA, Takahashi M, Burnett JC, Ouellet DL, Rossi JJ. Nucleolar Localization of HIV-1 Rev is Required Yet Insufficient for Production of Infectious Viral Particles. Aids Research and Human Retroviruses. PMID 29804468 DOI: 10.1089/Aid.2017.0306  0.575
2018 Zhou J, Lazar D, Li H, Xia X, Satheesan S, Charlins P, O'Mealy D, Akkina R, Saayman S, Weinberg MS, Rossi JJ, Morris KV. Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1. Theranostics. 8: 1575-1590. PMID 29556342 DOI: 10.7150/Thno.23085  0.523
2018 Satheesan S, Li H, Burnett JC, Takahashi M, Li S, Wu SX, Synold TW, Rossi JJ, Zhou J. HIV replication and latency in a humanized NSG mouse model during suppressive oral combinational ART. Journal of Virology. PMID 29343582 DOI: 10.1128/Jvi.02118-17  0.565
2018 Hori SI, Herrera A, Rossi JJ, Zhou J. Current Advances in Aptamers for Cancer Diagnosis and Therapy. Cancers. 10. PMID 29301363 DOI: 10.3390/Cancers10010009  0.32
2017 Pang KM, Castanotto D, Li H, Scherer L, Rossi JJ. Incorporation of aptamers in the terminal loop of shRNAs yields an effective and novel combinatorial targeting strategy. Nucleic Acids Research. PMID 29077949 DOI: 10.1093/Nar/Gkx980  0.515
2017 Voutila J, Reebye V, Roberts TC, Protopapa P, Andrikakou P, Blakey DC, Habib R, Huber H, Saetrom P, Rossi JJ, Habib NA. Development and Mechanism of Small Activating RNA Targeting CEBPA, a Novel Therapeutic in Clinical Trials for Liver Cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28882451 DOI: 10.1016/J.Ymthe.2017.07.018  0.432
2017 Yoon S, Rossi JJ. Emerging cancer-specific therapeutic aptamers. Current Opinion in Oncology. PMID 28692589 DOI: 10.1097/Cco.0000000000000389  0.3
2017 Yoon S, Rossi JJ. Treatment of Pancreatic Cancer by Aptamer Conjugated C/EBPα-saRNA. Advances in Experimental Medicine and Biology. 983: 173-188. PMID 28639199 DOI: 10.1007/978-981-10-4310-9_12  0.355
2017 Song MS, Rossi JJ. Molecular mechanisms of Dicer: endonuclease and enzymatic activity. The Biochemical Journal. 474: 1603-1618. PMID 28473628 DOI: 10.1042/Bcj20160759  0.401
2017 Yoon S, Armstrong B, Habib N, Rossi JJ. Blind SELEX Approach Identifies RNA Aptamer that Regulate EMT and Inhibit Metastasis. Molecular Cancer Research : McR. PMID 28396463 DOI: 10.1158/1541-7786.Mcr-16-0462  0.334
2017 Yoon S, Huang KW, Reebye V, Spalding D, Przytycka TM, Wang Y, Swiderski P, Li L, Armstrong B, Reccia I, Zacharoulis D, Dimas K, Kusano T, Shively J, Habib N, ... Rossi JJ, et al. Aptamer-Drug Conjugates of Active Metabolites of Nucleoside Analogs and Cytotoxic Agents Inhibit Pancreatic Tumor Cell Growth. Molecular Therapy. Nucleic Acids. 6: 80-88. PMID 28325302 DOI: 10.1016/J.Omtn.2016.11.008  0.307
2017 Galon J, Rossi J, Turcan S, Danan C, Locke FL, Neelapu SS, Miklos DB, Bartlett NL, Jacobson CA, Braunschweig I, Oluwole OO, Siddiqi T, Lin Y, Timmerman J, Reagan PM, et al. Characterization of anti-CD19 chimeric antigen receptor (CAR) T cell-mediated tumor microenvironment immune gene profile in a multicenter trial (ZUMA-1) with axicabtagene ciloleucel (axi-cel, KTE-C19). Journal of Clinical Oncology. 35: 3025-3025. DOI: 10.1200/Jco.2017.35.15_Suppl.3025  0.319
2017 Habib N, Reebye V, Zhao X, Voutila J, Habib R, Sætrom P, Huber H, Huang K, Rossi JJ, Blakey DC. Abstract 1508: MTL-CEBPA activates the transcription factor CEBPalpha leading to inhibition of hepatocellular cancer growth Cancer Research. 77: 1508-1508. DOI: 10.1158/1538-7445.Am2017-1508  0.32
2016 Anderson J, Li MJ, Palmer B, Remling L, Li S, Yam P, Yee JK, Rossi J, Zaia J, Akkina R. Safety and Efficacy of a Lentiviral Vector Containing Three Anti-HIV Genes-CCR5 Ribozyme, Tat-rev siRNA, and TAR Decoy-in SCID-hu Mouse-Derived T Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1182-1188. PMID 28182923 DOI: 10.1038/sj.mt.6300157  0.372
2016 Zhou J, Rossi J. Aptamers as targeted therapeutics: current potential and challenges. Nature Reviews. Drug Discovery. PMID 27807347 DOI: 10.1038/Nrd.2016.199  0.373
2016 Takahashi M, Wu X, Ho M, Chomchan P, Rossi JJ, Burnett JC, Zhou J. High throughput sequencing analysis of RNA libraries reveals the influences of initial library and PCR methods on SELEX efficiency. Scientific Reports. 6: 33697. PMID 27652575 DOI: 10.1038/Srep33697  0.532
2016 Dao P, Hoinka J, Takahashi M, Zhou J, Ho M, Wang Y, Costa F, Rossi JJ, Backofen R, Burnett J, Przytycka TM. AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments. Cell Systems. 3: 62-70. PMID 27467247 DOI: 10.1016/J.Cels.2016.07.003  0.524
2016 Yoon S, Huang KW, Reebye V, Mintz P, Tien YW, Lai HS, Sætrom P, Reccia I, Swiderski P, Armstrong B, Jozwiak A, Spalding D, Jiao L, Habib N, Rossi JJ. Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma (PDAC)-specific RNA aptamers Inhibits Tumor Growth in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26983359 DOI: 10.1038/Mt.2016.60  0.419
2016 Zhou J, Rossi JJ. Evolution of Cell-Type-Specific RNA Aptamers Via Live Cell-Based SELEX. Methods in Molecular Biology (Clifton, N.J.). 1421: 191-214. PMID 26965267 DOI: 10.1007/978-1-4939-3591-8_16  0.409
2016 Cui Q, Yang S, Ye P, Tian E, Sun G, Zhou J, Sun G, Liu X, Chen C, Murai K, Zhao C, Azizian KT, Yang L, Warden C, Wu X, ... ... Rossi JJ, et al. Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis. Nature Communications. 7: 10637. PMID 26838672 DOI: 10.1038/Ncomms10637  0.345
2016 Bobbin ML, Rossi JJ. RNA Interference (RNAi)-Based Therapeutics: Delivering on the Promise? Annual Review of Pharmacology and Toxicology. 56: 103-22. PMID 26738473 DOI: 10.1146/Annurev-Pharmtox-010715-103633  0.347
2016 Jung U, Takahashi M, Rossi JJ, Burnett JC. LGIT In Vitro Latency Model in Primary and T Cell Lines to Test HIV-1 Reactivation Compounds. Methods in Molecular Biology (Clifton, N.J.). 1354: 255-64. PMID 26714717 DOI: 10.1007/978-1-4939-3046-3_17  0.574
2016 Yoon S, Huang K, Habib N, Rossi J. 671. Potent Anti-Tumor Effects of ApDCs (Aptamer Drug Conjugates) for Targeted Therapeutics in Pancreatic Cancer Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33479-7  0.355
2016 Takahashi M, Li H, Aishwarya V, Damha MJ, Rossi JJ. 586. Dimerization Inhibition of HIV-1 RNA by 2’-Deoxy-2’-fluoro-beta-D-arabinose Nucleic Acid (2’-FANA) Modified Antisense Oligonucleotides Results in Potential Inhibition of Viral Expression Molecular Therapy. 24: S232-S233. DOI: 10.1016/S1525-0016(16)33394-9  0.52
2016 Blakey D, Reebye V, Voutila J, Habib R, Saetrom P, Huber H, Huang KW, Rossi J, Habib N. Small activating RNA to CEBPA as a novel therapeutic approach to treat patients with liver cancer European Journal of Cancer. 69. DOI: 10.1016/S0959-8049(16)33043-X  0.357
2015 Madu IG, Li S, Li B, Li H, Chang T, Li YJ, Vega R, Rossi J, Yee JK, Zaia J, Chen Y. A Novel Class of HIV-1 Antiviral Agents Targeting HIV via a SUMOylation-Dependent Mechanism. Scientific Reports. 5: 17808. PMID 26643614 DOI: 10.1038/Srep17808  0.39
2015 Castanotto D, Lin M, Kowolik C, Wang L, Ren XQ, Soifer HS, Koch T, Hansen BR, Oerum H, Armstrong B, Wang Z, Bauer P, Rossi J, Stein CA. A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells. Nucleic Acids Research. PMID 26433227 DOI: 10.1093/Nar/Gkv964  0.364
2015 Petz LD, Burnett JC, Li H, Li S, Tonai R, Bakalinskaya M, Shpall EJ, Armitage S, Kurtzberg J, Regan DM, Clark P, Querol S, Gutman JA, Spellman SR, Gragert L, ... Rossi JJ, et al. Progress toward curing HIV infection with hematopoietic cell transplantation. Stem Cells and Cloning : Advances and Applications. 8: 109-16. PMID 26251620 DOI: 10.2147/SCCAA.S56050  0.496
2015 Jung U, Urak K, Veillette M, Nepveu-Traversy MÉ, Pham QT, Hamel S, Rossi JJ, Berthoux L. Preclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 Transgene. Human Gene Therapy. 26: 664-79. PMID 26076730 DOI: 10.1089/hum.2015.059  0.305
2015 Bobbin ML, Burnett JC, Rossi JJ. RNA interference approaches for treatment of HIV-1 infection. Genome Medicine. 7: 50. PMID 26019725 DOI: 10.1186/S13073-015-0174-Y  0.626
2015 Li Y, Wu X, Gao H, Jin JM, Li AX, Kim YS, Pal SK, Nelson RA, Lau CM, Guo C, Mu B, Wang J, Wang F, Wang J, Zhao Y, ... ... Rossi JJ, et al. PIWI-interacting RNAs are dysregulated in renal cell carcinoma and associated with tumor metastasis and cancer specific survival. Molecular Medicine (Cambridge, Mass.). PMID 25998508 DOI: 10.2119/Molmed.2014.00203  0.372
2015 Zhou J, Rossi JJ, Shum KT. Methods for assembling B-cell lymphoma specific and internalizing aptamer-siRNA nanoparticles via the sticky bridge. Methods in Molecular Biology (Clifton, N.J.). 1297: 169-85. PMID 25896003 DOI: 10.1007/978-1-4939-2562-9_12  0.361
2015 Rossi JJ. Twenty-five plus years of an RNA addiction. Rna (New York, N.Y.). 21: 721-2. PMID 25780208 DOI: 10.1261/Rna.050120.115  0.439
2015 Finlay J, Roberts CM, Lowe G, Loeza J, Rossi JJ, Glackin CA. RNA-based TWIST1 inhibition via dendrimer complex to reduce breast cancer cell metastasis. Biomed Research International. 2015: 382745. PMID 25759817 DOI: 10.1155/2015/382745  0.329
2015 Takahashi M, Burnett JC, Rossi JJ. Aptamer-siRNA chimeras for HIV. Advances in Experimental Medicine and Biology. 848: 211-34. PMID 25757623 DOI: 10.1007/978-1-4939-2432-5_11  0.617
2015 Zhou J, Satheesan S, Li H, Weinberg MS, Morris KV, Burnett JC, Rossi JJ. Cell-specific RNA aptamer against human CCR5 specifically targets HIV-1 susceptible cells and inhibits HIV-1 infectivity. Chemistry & Biology. 22: 379-90. PMID 25754473 DOI: 10.1016/J.Chembiol.2015.01.005  0.629
2015 Daniels SM, Sinck L, Ward NJ, Melendez-Peña CE, Scarborough RJ, Azar I, Rance E, Daher A, Pang KM, Rossi JJ, Gatignol A. HIV-1 RRE RNA acts as an RNA silencing suppressor by competing with TRBP-bound siRNAs. Rna Biology. 12: 123-35. PMID 25668122 DOI: 10.1080/15476286.2015.1014759  0.478
2015 Shum KT, Rossi JJ. Noncoding oligonucleotides: the belle of the ball in gene therapy. Advances in Genetics. 89: 153-77. PMID 25620011 DOI: 10.1016/Bs.Adgen.2014.10.004  0.415
2015 Liu X, Liu C, Zhou J, Chen C, Qu F, Rossi JJ, Rocchi P, Peng L. Promoting siRNA delivery via enhanced cellular uptake using an arginine-decorated amphiphilic dendrimer. Nanoscale. 7: 3867-75. PMID 25283447 DOI: 10.1039/C4Nr04759A  0.413
2015 Jung U, Castanotto D, Jung M, Burnett J, Rossi JJ. 692. A Novel RNAi Trigger Design Retains Potent, Target Specific Activity Despite Emerging Mutations in the Target Site Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34301-5  0.583
2015 Takahashi M, Zhou J, Burnett JC, Rossi JJ. 581. Exploring Potency of Small RNAs for HIV Latency Reactivation Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34190-9  0.645
2015 Satheesan S, Li H, Takahashi M, Zhou J, Burnett J, Rossi JJ. 580. In Vivo Analyses of Aptamers and siRNA Therapeutics Against HIV-1 in Humanized Mouse Model Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34189-2  0.602
2015 Yoon S, Huang K, Mintz P, Habib N, Rossi JJ. 283. Targeted Delivery of C/EBPα-Small Activation RNA (saRNA) by RNA Aptamer Inhibits the Growth of Pancreatic Ductal Adenocarcinoma (PDAC) In Vivo Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33892-8  0.439
2015 Zhou J, Cui Q, Shi Y, Rossi JJ. 142. Evolution of Cell-Specific RNA Aptamers Against Glioblastoma Cancer Stem Cells Via Live Cell-Based SELEX Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33747-9  0.407
2015 Lazar DC, Zhou J, Saayman S, Rossi JJ, Morris KV, Weinburg MS. 62. Aptamer-siRNA Conjugate Directed Transcriptional Gene Silencing in HIV-1 Infected T Cells Molecular Therapy. 23: S27-S28. DOI: 10.1016/S1525-0016(16)33667-X  0.507
2014 Zhang X, Li H, Burnett JC, Rossi JJ. The role of antisense long noncoding RNA in small RNA-triggered gene activation. Rna (New York, N.Y.). 20: 1916-28. PMID 25344398 DOI: 10.1261/Rna.043968.113  0.604
2014 Liu X, Zhou J, Yu T, Chen C, Cheng Q, Sengupta K, Huang Y, Li H, Liu C, Wang Y, Posocco P, Wang M, Cui Q, Giorgio S, Fermeglia M, ... ... Rossi JJ, et al. Adaptive amphiphilic dendrimer-based nanoassemblies as robust and versatile siRNA delivery systems. Angewandte Chemie (International Ed. in English). 53: 11822-7. PMID 25219970 DOI: 10.1002/Anie.201406764  0.309
2014 Zhou J, Rossi J. Cell-type-specific aptamer and aptamer-small interfering RNA conjugates for targeted human immunodeficiency virus type 1 therapy. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 62: 914-9. PMID 25118114 DOI: 10.1097/Jim.0000000000000103  0.499
2014 Chadalavada D, Adamson TW, Burnett JC, Chen RW, Rossi JJ. Irradiated compared with nonirradiated NSG mice for the development of a human B-cell lymphoma model. Comparative Medicine. 64: 179-85. PMID 24956209  0.394
2014 Zhou J, Rossi JJ. Cell-type-specific, Aptamer-functionalized Agents for Targeted Disease Therapy. Molecular Therapy. Nucleic Acids. 3: e169. PMID 24936916 DOI: 10.1038/Mtna.2014.21  0.37
2014 Chung J, Scherer LJ, Gu A, Gardner AM, Torres-Coronado M, Epps EW, Digiusto DL, Rossi JJ. Optimized lentiviral vectors for HIV gene therapy: multiplexed expression of small RNAs and inclusion of MGMT(P140K) drug resistance gene. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 952-63. PMID 24576853 DOI: 10.1038/Mt.2014.32  0.523
2014 Reebye V, Sætrom P, Mintz PJ, Huang KW, Swiderski P, Peng L, Liu C, Liu X, Lindkaer-Jensen S, Zacharoulis D, Kostomitsopoulos N, Kasahara N, Nicholls JP, Jiao LR, Pai M, ... ... Rossi JJ, et al. Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo. Hepatology (Baltimore, Md.). 59: 216-27. PMID 23929703 DOI: 10.1002/Hep.26669  0.378
2014 Gatignol A, Daniels S, Sinck L, Ward N, Melendez-Peña C, Scarborough R, Azar I, Daher A, Pang K, Rossi J. Competition between HIV-1-encoded RRE RNA and miRNA-TRBP interactions alters RNA interference activity and gene expression Bmc Infectious Diseases. 14: 1-1. DOI: 10.1186/1471-2334-14-S2-O13  0.477
2014 Zhou J, Ding Y, Burnett JC, Rossi J. Retroviruses for Cancer Therapy Cancer Gene Therapy by Viral and Non-Viral Vectors. 21-38. DOI: 10.1002/9781118501665.ch2  0.382
2013 Shum KT, Zhou J, Rossi JJ. Nucleic Acid Aptamers as Potential Therapeutic and Diagnostic Agents for Lymphoma. Journal of Cancer Therapy. 4: 872-890. PMID 25057429 DOI: 10.4236/Jct.2013.44099  0.376
2013 Shum KT, Zhou J, Rossi JJ. Aptamer-based therapeutics: new approaches to combat human viral diseases. Pharmaceuticals (Basel, Switzerland). 6: 1507-42. PMID 24287493 DOI: 10.3390/Ph6121507  0.371
2013 DiGiusto DL, Stan R, Krishnan A, Li H, Rossi JJ, Zaia JA. Development of hematopoietic stem cell based gene therapy for HIV-1 infection: considerations for proof of concept studies and translation to standard medical practice. Viruses. 5: 2898-919. PMID 24284880 DOI: 10.3390/V5112898  0.422
2013 Ouellet DL, Vigneault-Edwards J, Létourneau K, Gobeil LA, Plante I, Burnett JC, Rossi JJ, Provost P. Regulation of host gene expression by HIV-1 TAR microRNAs. Retrovirology. 10: 86. PMID 23938024 DOI: 10.1186/1742-4690-10-86  0.572
2013 Snead NM, Escamilla-Powers JR, Rossi JJ, McCaffrey AP. 5' Unlocked Nucleic Acid Modification Improves siRNA Targeting. Molecular Therapy. Nucleic Acids. 2: e103. PMID 23820891 DOI: 10.1038/Mtna.2013.36  0.464
2013 Nechaev S, Gao C, Moreira D, Swiderski P, Jozwiak A, Kowolik CM, Zhou J, Armstrong B, Raubitschek A, Rossi JJ, Kortylewski M. Intracellular processing of immunostimulatory CpG-siRNA: Toll-like receptor 9 facilitates siRNA dicing and endosomal escape. Journal of Controlled Release : Official Journal of the Controlled Release Society. 170: 307-15. PMID 23777886 DOI: 10.1016/J.Jconrel.2013.06.007  0.375
2013 Reebye V, Sætrom P, Mintz PJ, Rossi JJ, Kasahara N, Nteliopoulos G, Nicholls J, Haoudi A, Gordon M, Habib NA. A Short-activating RNA Oligonucleotide Targeting the Islet β-cell Transcriptional Factor MafA in CD34(+) Cells. Molecular Therapy. Nucleic Acids. 2: e97. PMID 23736775 DOI: 10.1038/Mtna.2013.23  0.346
2013 Zhou J, Shum KT, Burnett JC, Rossi JJ. Nanoparticle-Based Delivery of RNAi Therapeutics: Progress and Challenges. Pharmaceuticals (Basel, Switzerland). 6: 85-107. PMID 23667320 DOI: 10.3390/Ph6010085  0.546
2013 Ehsani A, Alluin JV, Rossi JJ. Cell cycle abnormalities associated with differential perturbations of the human U5 snRNP associated U5-200kD RNA helicase. Plos One. 8: e62125. PMID 23637979 DOI: 10.1371/Journal.Pone.0062125  0.423
2013 Snead NM, Wu X, Li A, Cui Q, Sakurai K, Burnett JC, Rossi JJ. Molecular basis for improved gene silencing by Dicer substrate interfering RNA compared with other siRNA variants. Nucleic Acids Research. 41: 6209-21. PMID 23620279 DOI: 10.1093/Nar/Gkt200  0.608
2013 Cillo AR, Krishnan A, Mitsuyasu RT, McMahon DK, Li S, Rossi JJ, Zaia JA, Mellors JW. Plasma viremia and cellular HIV-1 DNA persist despite autologous hematopoietic stem cell transplantation for HIV-related lymphoma. Journal of Acquired Immune Deficiency Syndromes (1999). 63: 438-41. PMID 23493152 DOI: 10.1097/Qai.0B013E31828E6163  0.364
2013 Zhou J, Tiemann K, Chomchan P, Alluin J, Swiderski P, Burnett J, Zhang X, Forman S, Chen R, Rossi J. Dual functional BAFF receptor aptamers inhibit ligand-induced proliferation and deliver siRNAs to NHL cells. Nucleic Acids Research. 41: 4266-83. PMID 23470998 DOI: 10.1093/Nar/Gkt125  0.546
2013 Chung J, DiGiusto DL, Rossi JJ. Combinatorial RNA-based gene therapy for the treatment of HIV/AIDS. Expert Opinion On Biological Therapy. 13: 437-45. PMID 23394377 DOI: 10.1517/14712598.2013.761968  0.428
2013 Zhang Q, Hossain DM, Nechaev S, Kozlowska A, Zhang W, Liu Y, Kowolik CM, Swiderski P, Rossi JJ, Forman S, Pal S, Bhatia R, Raubitschek A, Yu H, Kortylewski M. TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo. Blood. 121: 1304-15. PMID 23287859 DOI: 10.1182/Blood-2012-07-442590  0.37
2013 Zhou J, Neff CP, Swiderski P, Li H, Smith DD, Aboellail T, Remling-Mulder L, Akkina R, Rossi JJ. Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 192-200. PMID 23164935 DOI: 10.1038/Mt.2012.226  0.484
2013 Petz LD, Redei I, Bryson Y, Regan D, Kurtzberg J, Shpall E, Gutman J, Querol S, Clark P, Tonai R, Santos S, Bravo A, Spellman S, Gragert L, Rossi J, et al. Hematopoietic cell transplantation with cord blood for cure of HIV infections. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 393-7. PMID 23089564 DOI: 10.1016/J.Bbmt.2012.10.017  0.33
2013 Li Y, Wu X, Gao H, Jin J, Pal S, Li A, Guo C, Nelson R, Wang J, Kim Y, Wang F, Wang J, Chen W, Wang S, Rossi J, et al. Abstract LB-247: 5′-tRFHis-GTG, a novel tRNA-derived novel miRNA-like small non-coding RNA, aberrantly expressed in metastatic renal cell carcinoma by promoting tumor cell proliferation, migration and invasion. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-247  0.393
2013 Huang KW, Reebye V, Mintz PJ, Saetrom P, Swiderski P, Peng L, Liu C, Liu XX, Jensen SL, Zacharoulis D, Kostomitsopoulos N, Kasahara N, Nicholls J, Jiao LR, Pai M, ... ... Rossi JJ, et al. Abstract B225: Short activating RNA (saRNA) targeting C/EBPA significantly inhibits cell proliferation of undifferentiated cancer cells. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B225  0.355
2012 Voutila J, Sætrom P, Mintz P, Sun G, Alluin J, Rossi JJ, Habib NA, Kasahara N. Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells. Molecular Therapy. Nucleic Acids. 1: e35. PMID 23344177 DOI: 10.1038/Mtna.2012.20  0.434
2012 Zhou J, Song MS, Jacobi AM, Behlke MA, Wu X, Rossi JJ. Deep Sequencing Analyses of DsiRNAs Reveal the Influence of 3' Terminal Overhangs on Dicing Polarity, Strand Selectivity, and RNA Editing of siRNAs. Molecular Therapy. Nucleic Acids. 1: e17. PMID 23343928 DOI: 10.1038/Mtna.2012.6  0.409
2012 Frederickson RM, Rossi JJ. Molecular Therapy's New Open-access Sibling. Molecular Therapy. Nucleic Acids. 1: e13. PMID 23343882 DOI: 10.1038/Mtna.2012.7  0.329
2012 Zhou J, Bobbin ML, Burnett JC, Rossi JJ. Current progress of RNA aptamer-based therapeutics. Frontiers in Genetics. 3: 234. PMID 23130020 DOI: 10.3389/Fgene.2012.00234  0.608
2012 Zhou J, Rossi JJ. Therapeutic potential of aptamer-siRNA conjugates for treatment of HIV-1. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 26: 393-400. PMID 23046156 DOI: 10.2165/11635350-000000000-00000  0.481
2012 Burnett JC, Zaia JA, Rossi JJ. Creating genetic resistance to HIV. Current Opinion in Immunology. 24: 625-32. PMID 22985479 DOI: 10.1016/J.Coi.2012.08.013  0.608
2012 Chung J, Zhang J, Li H, Ouellet DL, DiGiusto DL, Rossi JJ. Endogenous MCM7 microRNA cluster as a novel platform to multiplex small interfering and nucleolar RNAs for combinational HIV-1 gene therapy. Human Gene Therapy. 23: 1200-8. PMID 22834872 DOI: 10.1089/Hum.2012.011  0.526
2012 Snead NM, Rossi JJ. RNA interference trigger variants: getting the most out of RNA for RNA interference-based therapeutics. Nucleic Acid Therapeutics. 22: 139-46. PMID 22703279 DOI: 10.1089/Nat.2012.0361  0.447
2012 Aagaard L, Bjerregaard B, Kjeldbjerg AL, Pedersen FS, Larsson LI, Rossi JJ. Silencing of endogenous envelope genes in human choriocarcinoma cells shows that envPb1 is involved in heterotypic cell fusions. The Journal of General Virology. 93: 1696-1699. PMID 22573740 DOI: 10.1099/Vir.0.041764-0  0.402
2012 Unwalla HJ, Rossi JJ. Screening effective target sites on mRNA: a ribozyme library approach. Methods in Molecular Biology (Clifton, N.J.). 848: 329-36. PMID 22315078 DOI: 10.1007/978-1-61779-545-9_20  0.454
2012 Burnett JC, Rossi JJ. RNA-based therapeutics: current progress and future prospects. Chemistry & Biology. 19: 60-71. PMID 22284355 DOI: 10.1016/J.Chembiol.2011.12.008  0.612
2012 Sun G, Li H, Wu X, Covarrubias M, Scherer L, Meinking K, Luk B, Chomchan P, Alluin J, Gombart AF, Rossi JJ. Interplay between HIV-1 infection and host microRNAs. Nucleic Acids Research. 40: 2181-96. PMID 22080513 DOI: 10.1093/Nar/Gkr961  0.397
2012 Chen RW, Chomchan P, Chadalavada D, Alluin J, Zhou j, Forman SJ, Rossi J. BAFF-R Aptamer/STAT3 siRNA Construct Selectively Downregulates STAT3 mRNA in BAFF-R Expressing Lymphomas in Vitro and in Vivo Blood. 120: 65-65. DOI: 10.1182/Blood.V120.21.65.65  0.302
2012 Wu X, Somlo G, Palomares M, Yen Y, Rossi J, Gao H, Wang SE. Abstract A9: De novo sequencing of circulating microRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer Cancer Research. 72: A9-A9. DOI: 10.1158/1538-7445.Nonrna12-A9  0.305
2011 Chung J, Rossi JJ, Jung U. Current progress and challenges in HIV gene therapy. Future Virology. 6: 1319-1328. PMID 22754586 DOI: 10.2217/Fvl.11.113  0.405
2011 Rossi JJ. The development of RNA interference therapeutics. Nucleic Acid Therapeutics. 21: 371-2. PMID 22196369 DOI: 10.1089/Nat.2011.1503  0.413
2011 Rossi JJ. A novel nuclear miRNA mediated modulation of a non-coding antisense RNA and its cognate sense coding mRNA. The Embo Journal. 30: 4340-1. PMID 22048334 DOI: 10.1038/Emboj.2011.373  0.358
2011 Sun G, Wu X, Wang J, Li H, Li X, Gao H, Rossi J, Yen Y. A bias-reducing strategy in profiling small RNAs using Solexa. Rna (New York, N.Y.). 17: 2256-62. PMID 22016383 DOI: 10.1261/Rna.028621.111  0.401
2011 Zhou J, Rossi JJ. Current progress in the development of RNAi-based therapeutics for HIV-1 Gene Therapy. 18: 1134-1138. PMID 21956690 DOI: 10.1038/Gt.2011.149  0.424
2011 Zhou J, Neff CP, Liu X, Zhang J, Li H, Smith DD, Swiderski P, Aboellail T, Huang Y, Du Q, Liang Z, Peng L, Akkina R, Rossi JJ. Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 2228-38. PMID 21952167 DOI: 10.1038/Mt.2011.207  0.43
2011 Sun G, Rossi JJ. MicroRNAs and their potential involvement in HIV infection Trends in Pharmacological Sciences. 32: 675-681. PMID 21862142 DOI: 10.1016/J.Tips.2011.07.003  0.401
2011 Tiemann K, Alluin JV, Honegger A, Chomchan P, Gaur S, Yun Y, Forman SJ, Rossi JJ, Chen RW. Small interfering RNAs targeting cyclin D1 and cyclin D2 enhance the cytotoxicity of chemotherapeutic agents in mantle cell lymphoma cell lines. Leukemia & Lymphoma. 52: 2148-54. PMID 21745168 DOI: 10.3109/10428194.2011.593272  0.434
2011 Burnett JC, Rossi JJ, Tiemann K. Current progress of siRNA/shRNA therapeutics in clinical trials. Biotechnology Journal. 6: 1130-46. PMID 21744502 DOI: 10.1002/Biot.201100054  0.595
2011 Zhou J, Li H, Zhang J, Piotr S, Rossi J. Development of cell-type specific anti-HIV gp120 aptamers for siRNA delivery. Journal of Visualized Experiments : Jove. PMID 21730942 DOI: 10.3791/2954  0.48
2011 Zhang X, Rossi JJ. Phylogenetic Comparison of Small RNA-triggered Transcriptional Gene Silencing Journal of Biological Chemistry. 286: 29443-29448. PMID 21730056 DOI: 10.1074/Jbc.R111.276378  0.419
2011 Li L, Modi H, McDonald T, Rossi J, Yee JK, Bhatia R. A critical role for SHP2 in STAT5 activation and growth factor-mediated proliferation, survival, and differentiation of human CD34+ cells. Blood. 118: 1504-15. PMID 21670473 DOI: 10.1182/Blood-2010-06-288910  0.322
2011 Shukla GC, Haque F, Tor Y, Wilhelmsson LM, Toulmé JJ, Isambert H, Guo P, Rossi JJ, Tenenbaum SA, Shapiro BA. A boost for the emerging field of RNA nanotechnology. Acs Nano. 5: 3405-18. PMID 21604810 DOI: 10.1021/Nn200989R  0.405
2011 Gu S, Jin L, Zhang F, Huang Y, Grimm D, Rossi JJ, Kay MA. Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes. Proceedings of the National Academy of Sciences of the United States of America. 108: 9208-13. PMID 21576459 DOI: 10.1073/Pnas.1018023108  0.427
2011 Scherer LJ, Rossi JJ. Ex vivo gene therapy for HIV-1 treatment Human Molecular Genetics. 20. PMID 21505069 DOI: 10.1093/Hmg/Ddr160  0.427
2011 Rossi JJ. Stopping RNA interference at the seed. Nature Genetics. 43: 288-289. PMID 21445071 DOI: 10.1038/Ng0411-288  0.332
2011 Zhou J, Rossi JJ. Aptamer-targeted RNAi for HIV-1 therapy. Methods of Molecular Biology. 721: 355-371. PMID 21431697 DOI: 10.1007/978-1-61779-037-9_22  0.507
2011 Zhou J, Rossi JJ. Progress in RNAi-based Antiviral Therapeutics Methods of Molecular Biology. 721: 67-75. PMID 21431679 DOI: 10.1007/978-1-61779-037-9_4  0.515
2011 Rossi JJ. RNA nanoparticles come of age. Acta Biochimica Et Biophysica Sinica. 43: 245-247. PMID 21430091 DOI: 10.1093/Abbs/Gmr018  0.414
2011 Rossi JJ. Inducible and reversible breaching of the blood brain barrier by RNAi Embo Molecular Medicine. 3: 186-188. PMID 21394916 DOI: 10.1002/Emmm.201100132  0.462
2011 Zhou J, Shu Y, Guo P, Smith DD, Rossi JJ. Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibition. Methods (San Diego, Calif.). 54: 284-94. PMID 21256218 DOI: 10.1016/J.Ymeth.2010.12.039  0.488
2011 Neff CP, Zhou J, Remling L, Kuruvilla J, Zhang J, Li H, Smith DD, Swiderski P, Rossi JJ, Akkina R. An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice. Science Translational Medicine. 3: 66ra6. PMID 21248316 DOI: 10.1126/Scitranslmed.3001581  0.464
2011 Rossi JJ. OTS highlights advance in basic and translational aspects of oligonucleotide research. Molecular Therapy. 19: 1-2. PMID 21200390 DOI: 10.1038/Mt.2010.285  0.422
2011 Zhou J, Rossi JJ. Cell-specific aptamer-mediated targeted drug delivery. Oligonucleotides. 21: 1-10. PMID 21182455 DOI: 10.1089/Oli.2010.0264  0.407
2011 Modi H, Li L, Chu S, Rossi J, Yee JK, Bhatia R. Inhibition of Grb2 expression demonstrates an important role in BCR-ABL-mediated MAPK activation and transformation of primary human hematopoietic cells. Leukemia. 25: 305-12. PMID 21072043 DOI: 10.1038/Leu.2010.257  0.335
2011 Sakurai K, Amarzguioui M, Kim DH, Alluin J, Heale B, Song MS, Gatignol A, Behlke MA, Rossi JJ. A role for human Dicer in pre-RISC loading of siRNAs. Nucleic Acids Research. 39: 1510-25. PMID 20972213 DOI: 10.1093/nar/gkq846  0.352
2011 Neff CP, Zhou J, Remling L, Kuruvilla J, Zhang J, Li H, Smith DD, Swiderski P, Rossi JJ, Akkina R. 133 Aptamer-siRNA Chimera Therapy Suppresses HIV-1 Viral Loads and Protects from CD4 T-Cell Loss in Humanized (RAG-hu) Mice Journal of Acquired Immune Deficiency Syndromes. 56: 54. DOI: 10.1097/01.Qai.0000397320.40083.Fa  0.369
2010 Snead NM, Rossi JJ. Biogenesis and function of endogenous and exogenous siRNAs Wiley Interdisciplinary Reviews - Rna. 1: 117-131. PMID 21956909 DOI: 10.1002/Wrna.14  0.464
2010 Lares MR, Rossi JJ, Ouellet DL. RNAi and small interfering RNAs in human disease therapeutic applications. Trends in Biotechnology. 28: 570-9. PMID 20833440 DOI: 10.1016/J.Tibtech.2010.07.009  0.426
2010 Kimpel J, Braun SE, Qiu G, Wong FE, Conolle M, Schmitz JE, Brendel C, Humeau LM, Dropulic B, Rossi JJ, Berger A, von Laer D, Johnson RP. Survival of the fittest: positive selection of CD4+ T cells expressing a membrane-bound fusion inhibitor following HIV-1 infection. Plos One. 5: e12357. PMID 20808813 DOI: 10.1371/Journal.Pone.0012357  0.435
2010 DiGiusto DL, Krishnan A, Li L, Li H, Li S, Rao A, Mi S, Yam P, Stinson S, Kalos M, Alvarnas J, Lacey SF, Yee JK, Li M, Couture L, ... Rossi JJ, et al. RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma. Science Translational Medicine. 2: 36ra43. PMID 20555022 DOI: 10.1126/Scitranslmed.3000931  0.47
2010 Sakurai K, Chomchan P, Rossi JJ. Silencing of gene expression in cultured cells using small interfering RNAs. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 27.1.1-28. PMID 20521232 DOI: 10.1002/0471143030.Cb2701S47  0.462
2010 Tiemann K, Höhn B, Ehsani A, Forman SJ, Rossi JJ, Sætrom P. Dual-targeting siRNAs Rna. 16: 1275-1284. PMID 20410240 DOI: 10.1261/Rna.2005710  0.39
2010 Burnett JC, Lim KI, Calafi A, Rossi JJ, Schaffer DV, Arkin AP. Combinatorial latency reactivation for HIV-1 subtypes and variants. Journal of Virology. 84: 5958-74. PMID 20357084 DOI: 10.1128/Jvi.00161-10  0.735
2010 Zhou J, Rossi JJ. Aptamer-targeted cell-specific RNA interference Silence. 1: 4-4. PMID 20226078 DOI: 10.1186/1758-907X-1-4  0.455
2010 Zhang J, Rossi JJ. Strategies in designing multigene expression units to downregulate HIV-1. Methods in Molecular Biology (Clifton, N.J.). 623: 123-36. PMID 20217548 DOI: 10.1007/978-1-60761-588-0_8  0.491
2010 Unwalla HJ, Rossi JJ. A dual function TAR Decoy serves as an anti-HIV siRNA delivery vehicle. Virology Journal. 7: 33-33. PMID 20144240 DOI: 10.1186/1743-422X-7-33  0.499
2010 Ehsani A, Saetrom P, Zhang J, Alluin J, Li H, Snøve O, Aagaard L, Rossi JJ. Rational design of micro-RNA-like bifunctional siRNAs targeting HIV and the HIV coreceptor CCR5. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 796-802. PMID 20104214 DOI: 10.1038/Mt.2009.321  0.492
2010 Kiem H-, Wu RA, Sun G, Laer DV, Rossi JJ, Trobridge GD. Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivo. Gene Therapy. 17: 37-49. PMID 19741733 DOI: 10.1038/Gt.2009.118  0.374
2010 Rossi JJ, Sun G, Kim D. Abstract CN07-04: RNAi in the treatment and epigenetics of cancer Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-Cn07-04  0.404
2009 Tiemann K, Rossi JJ. RNAi-based therapeutics–current status, challenges and prospects Embo Molecular Medicine. 1: 142-151. PMID 20049714 DOI: 10.1002/Emmm.200900023  0.442
2009 Castanotto D, Lingeman R, Riggs AD, Rossi JJ. CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs Proceedings of the National Academy of Sciences of the United States of America. 106: 21655-21659. PMID 19955415 DOI: 10.1073/Pnas.0912384106  0.328
2009 Trobridge GD, Wu RA, Beard BC, Chiu SY, Muñoz NM, von Laer D, Rossi JJ, Kiem HP. Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection. Plos One. 4: e7693. PMID 19888329 DOI: 10.1371/Journal.Pone.0007693  0.374
2009 Kortylewski M, Swiderski P, Herrmann A, Wang L, Kowolik C, Kujawski M, Lee H, Scuto A, Liu Y, Yang C, Deng J, Soifer HS, Raubitschek A, Forman S, Rossi JJ, et al. In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses. Nature Biotechnology. 27: 925-32. PMID 19749770 DOI: 10.1038/Nbt.1564  0.337
2009 Burnett JC, Rossi JJ. Autologous cell therapy for HIV: Stem cells, ribozymes and HIV Gene Therapy. 16: 1178-1179. PMID 19641534 DOI: 10.1038/Gt.2009.86  0.609
2009 Sun G, Rossi JJ. Problems associated with reporter assays in RNAi studies. Rna Biology. 6: 406-411. PMID 19617709 DOI: 10.4161/Rna.6.4.9218  0.404
2009 Kim DH, Rossi JJ. Transcriptional Gene Silencing Using Small RNAs Methods of Molecular Biology. 555: 119-125. PMID 19495692 DOI: 10.1007/978-1-60327-295-7_9  0.476
2009 Rossi JJ. Dotting the I's and crossing the T's: integration analyses in transduced patient T cells. Molecular Therapy. 17: 756-757. PMID 19404325 DOI: 10.1038/Mt.2009.75  0.381
2009 Kim DH, Rossi JJ. Overview of gene silencing by RNA interference. Current Protocols in Human Genetics. 36. PMID 19319858 DOI: 10.1002/0471142700.Nc1601S36  0.458
2009 Zhou J, Swiderski P, Li H, Zhang J, Neff CP, Akkina R, Rossi JJ. Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells Nucleic Acids Research. 37: 3094-3109. PMID 19304999 DOI: 10.1093/Nar/Gkp185  0.465
2009 Castanotto D, Rossi JJ. The promises and pitfalls of RNA-interference-based therapeutics Nature. 457: 426-433. PMID 19158789 DOI: 10.1038/Nature07758  0.457
2008 Kim D, Behlke M, Rossi JJ. Designing and utilization of siRNAs targeting RNA binding proteins. Methods of Molecular Biology. 488: 367-381. PMID 18982303 DOI: 10.1007/978-1-60327-475-3_24  0.448
2008 Soifer HS, Sano M, Sakurai K, Chomchan P, Saetrom P, Sherman MA, Collingwood MA, Behlke MA, Rossi JJ. A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs. Nucleic Acids Research. 36: 6511-22. PMID 18927112 DOI: 10.1093/Nar/Gkn687  0.385
2008 Kim DH, Saetrom P, Snøve O, Rossi JJ. MicroRNA-directed transcriptional gene silencing in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 16230-5. PMID 18852463 DOI: 10.1073/Pnas.0808830105  0.332
2008 Aagaard LA, Zhang J, Eije KJv, Li H, Sætrom P, Amarzguioui M, Rossi JJ. Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs Gene Therapy. 15: 1536-1549. PMID 18800151 DOI: 10.1038/Gt.2008.147  0.378
2008 Lee NS, Kim DH, Alluin J, Robbins M, Gu S, Li H, Kim J, Salvaterra PM, Rossi JJ. Functional and intracellular localization properties of U6 promoter-expressed siRNAs, shRNAs, and chimeric VA1 shRNAs in mammalian cells. Rna (New York, N.Y.). 14: 1823-33. PMID 18697923 DOI: 10.1261/Rna.1014008  0.447
2008 Li M, Rossi JJ. Lentiviral vector delivery of siRNA and shRNA encoding genes into cultured and primary hematopoietic cells. Methods in Molecular Biology (Clifton, N.J.). 433: 287-299. PMID 18679631 DOI: 10.1007/978-1-59745-237-3_18  0.334
2008 Collingwood MA, Rose SD, Huang L, Hillier C, Amarzguioui M, Wiiger MT, Soifer HS, Rossi JJ, Behlke MA. Chemical modification patterns compatible with high potency dicer-substrate small interfering RNAs. Oligonucleotides. 18: 187-200. PMID 18637735 DOI: 10.1089/Oli.2008.0123  0.378
2008 Kim D, Rossi J. RNAi mechanisms and applications. Biotechniques. 44: 613-6. PMID 18474035 DOI: 10.2144/000112792  0.451
2008 Zhou J, Li H, Li S, Zaia J, Rossi JJ. Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy Molecular Therapy. 16: 1481-1489. PMID 18461053 DOI: 10.1038/Mt.2008.92  0.451
2008 Rossi JJ. Realizing the promise of RNAi. Molecular Therapy. 16: 810-811. PMID 18432272 DOI: 10.1038/Mt.2008.55  0.459
2008 Unwalla H, Rossi JJ. Tat-regulated expression of RNA interference: Triggers for the treatment of HIV infection Current Hiv\/Aids Reports. 5: 40-43. PMID 18417034 DOI: 10.1007/S11904-008-0007-3  0.504
2008 Unwalla HJ, Li H, Li S, Abad D, Rossi JJ. Use of a U16 snoRNA-containing ribozyme library to identify ribozyme targets in HIV-1. Molecular Therapy. 16: 1113-1119. PMID 18388915 DOI: 10.1038/Mt.2008.54  0.493
2008 Rossi JJ. Expression Strategies for Short Hairpin RNA Interference Triggers Human Gene Therapy. 19: 313-317. PMID 18363506 DOI: 10.1089/Hum.2008.026  0.466
2008 Sano M, Li H, Nakanishi M, Rossi JJ. Expression of long anti-HIV-1 hairpin RNAs for the generation of multiple siRNAs: advantages and limitations. Molecular Therapy. 16: 170-177. PMID 17726454 DOI: 10.1038/Sj.Mt.6300298  0.489
2008 Chen RW, Htut M, Hoehn B, Berge E, Robinson W, Rossi J, Forman S, Bemis L. Truncation in CCND1 mRNA 3′ UTR Is Associated with An Aggressive Phenotype and Chemoresistance Blood. 112: 5287-5287. DOI: 10.1182/Blood.V112.11.5287.5287  0.316
2008 Krishnan A, Zaia JA, Rossi J, DiGiusto D, Kalos M, Couture L, Alvarnas J, Li M, Li H, Yee J, Yam P, Li S, Mi S, Li L, Hsu D, et al. First in Human Engraftment of Anti-HIV Lentiviral Vector Gene Modified CD34+ Peripheral Blood Progenitor Cells in the Treatment of AIDS Related Lymphoma (ARL). Blood. 112: 2348-2348. DOI: 10.1182/Blood.V112.11.2348.2348  0.454
2008 Chen TK, Moore TB, Territo M, Chow R, Tonai R, Petz L, Rossi J, Mitsuyasu R, Rosenthal J, Forman S, Zaia JA, Bryson YJ. 324: The Feasibility of using CCR5Δ32/Δ32 Hematopoietic Stem Cell Transplants for Immune Reconstitution in HIV-Infected Children Biology of Blood and Marrow Transplantation. 14: 119. DOI: 10.1016/J.Bbmt.2007.12.334  0.31
2008 Morris KV, Rossi JJ. Combinatorial RNA-based Therapies for HIV-1 Modern Biopharmaceuticals: Design, Development and Optimization. 2: 569-580. DOI: 10.1002/9783527620982.ch23  0.396
2007 Li M, Rossi JJ. Lentivirus transduction of hematopoietic cells. Csh Protocols. 2007. PMID 21357086 DOI: 10.1101/Pdb.Prot4755  0.373
2007 Rossi JJ, June CH, Kohn DB. Genetic therapies against HIV. Nature Biotechnology. 25: 1444-54. PMID 18066041 DOI: 10.1038/Nbt1367  0.482
2007 Soifer HS, Rossi JJ, Saetrom P. MicroRNAs in disease and potential therapeutic applications. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 2070-9. PMID 17878899 DOI: 10.1038/Sj.Mt.6300311  0.316
2007 Rossi JJ. Targeted cleavage: tuneable cis-cleaving ribozymes. Proceedings of the National Academy of Sciences of the United States of America. 104: 14881-14882. PMID 17855561 DOI: 10.1073/Pnas.0707141104  0.38
2007 Sun G, Li H, Rossi JJ. Cloning and detecting signature microRNAs from mammalian cells. Methods in Enzymology. 427: 123-138. PMID 17720482 DOI: 10.1016/S0076-6879(07)27007-7  0.359
2007 Castanotto D, Sakurai K, Lingeman R, Li H, Shively L, Aagaard L, Soifer H, Gatignol A, Riggs A, Rossi JJ. Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC. Nucleic Acids Research. 35: 5154-64. PMID 17660190 DOI: 10.1093/Nar/Gkm543  0.45
2007 Cantin EM, Rossi JJ. Molecular medicine: Entry granted Nature. 448: 33. PMID 17611531 DOI: 10.1038/448033A  0.365
2007 Scherer L, Rossi JJ, Weinberg MS. Progress and prospects: RNA-based therapies for treatment of HIV infection. Gene Therapy. 14: 1057-1064. PMID 17607313 DOI: 10.1038/Sj.Gt.3302977  0.465
2007 Kim JW, Zhang YH, Zern MA, Rossi JJ, Wu J. Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells. Biochemical and Biophysical Research Communications. 359: 292-7. PMID 17533113 DOI: 10.1016/J.Bbrc.2007.05.080  0.407
2007 Aagaard L, Rossi JJ. RNAi therapeutics: Principles, prospects and challenges ☆ Advanced Drug Delivery Reviews. 59: 75-86. PMID 17449137 DOI: 10.1016/J.Addr.2007.03.005  0.43
2007 Scherer LJ, Frank R, Rossi JJ. Optimization and characterization of tRNA-shRNA expression constructs Nucleic Acids Research. 35: 2620-2628. PMID 17426139 DOI: 10.1093/Nar/Gkm103  0.44
2007 Anderson J, Li MJ, Palmer B, Remling L, Li S, Yam P, Yee JK, Rossi J, Zaia J, Akkina R. Safety and efficacy of a lentiviral vector containing three anti-HIV genes--CCR5 ribozyme, tat-rev siRNA, and TAR decoy--in SCID-hu mouse-derived T cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1182-8. PMID 17406343 DOI: 10.1038/Sj.Mt.6300157  0.475
2007 Heidel JD, Liu JY, Yen Y, Zhou B, Heale BS, Rossi JJ, Bartlett DW, Davis ME. Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2207-15. PMID 17404105 DOI: 10.1158/1078-0432.Ccr-06-2218  0.391
2007 Held DM, Kissel JD, Thacker SJ, Michalowski D, Saran D, Ji J, Hardy RW, Rossi JJ, Burke DH. Cross-clade inhibition of recombinant human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus SIVcpz reverse transcriptases by RNA pseudoknot aptamers. Journal of Virology. 81: 5375-84. PMID 17329328 DOI: 10.1128/Jvi.01923-06  0.456
2007 Aagaard L, Amarzguioui M, Sun G, Santos LC, Ehsani A, Prydz H, Rossi JJ. A facile lentiviral vector system for expression of doxycycline-inducible shRNAs: knockdown of the pre-miRNA processing enzyme Drosha. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 938-45. PMID 17311008 DOI: 10.1038/Sj.Mt.6300118  0.388
2007 Kim DH, Rossi JJ. Strategies for silencing human disease using RNA interference. Nature Reviews. Genetics. 8: 173-84. PMID 17304245 DOI: 10.1038/Nrg2006  0.386
2007 Rossi JJ. Transcriptional activation by small RNA duplexes Nature Chemical Biology. 3: 136-137. PMID 17301798 DOI: 10.1038/Nchembio0307-136  0.438
2007 Li N, Wang Y, Forbes K, Vignali KM, Heale BS, Saftig P, Hartmann D, Black RA, Rossi JJ, Blobel CP, Dempsey PJ, Workman CJ, Vignali DA. Metalloproteases regulate T-cell proliferation and effector function via LAG-3. The Embo Journal. 26: 494-504. PMID 17245433 DOI: 10.1038/Sj.Emboj.7601520  0.303
2007 Höhn B, Soifer HS, Forman SJ, Rossi JJ. Bifunctional siRNA Design Targeting Non-Hodgkin’s Lymphoma. Blood. 110: 2357-2357. DOI: 10.1182/Blood.V110.11.2357.2357  0.473
2006 Unwalla HJ, Rossi JJ. Promoting gene therapy: expression systems for transgenes and posttranscriptional gene silencing. Biotechnology & Genetic Engineering Reviews. 23: 71-91. PMID 22530503 DOI: 10.1080/02648725.2006.10648079  0.418
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2006 Kolb G, Reigadas S, Castanotto D, Faure A, Ventura M, Rossi JJ, Toulmé JJ. Endogenous expression of an anti-TAR aptamer reduces HIV-1 replication Rna Biology. 3: 150-156. PMID 17299271 DOI: 10.4161/Rna.3.4.3811  0.446
2006 Snøve O, Rossi JJ. Chemical modifications rescue off-target effects of RNAi. Acs Chemical Biology. 1: 274-276. PMID 17163754 DOI: 10.1021/Cb6002256  0.301
2006 Gu S, Ji J, Kim JD, Yee JK, Rossi JJ. Inhibition of infectious human immunodeficiency virus type 1 virions via lentiviral vector encoded short antisense RNAs. Oligonucleotides. 16: 287-95. PMID 17155905 DOI: 10.1089/Oli.2006.16.287  0.41
2006 Li M, Li H, Rossi JJ. RNAi in combination with a ribozyme and TAR decoy for treatment of HIV infection in hematopoietic cell gene therapy. Annals of the New York Academy of Sciences. 1082: 172-9. PMID 17145937 DOI: 10.1196/Annals.1348.006  0.438
2006 Soifer HS, Rossi JJ. Small interfering RNAs to the rescue: blocking L1 retrotransposition. Nature Structural & Molecular Biology. 13: 758-9. PMID 16955095 DOI: 10.1038/Nsmb0906-758  0.395
2006 Paul S, Dansithong W, Kim D, Rossi J, Webster NJ, Comai L, Reddy S. Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing. The Embo Journal. 25: 4271-83. PMID 16946708 DOI: 10.1038/Sj.Emboj.7601296  0.328
2006 Snøve O, Rossi JJ. Toxicity in mice expressing short hairpin RNAs gives new insight into RNAi. Genome Biology. 7: 231-231. PMID 16942630 DOI: 10.1186/Gb-2006-7-8-231  0.443
2006 Kim DH, Villeneuve LM, Morris KV, Rossi JJ. Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nature Structural & Molecular Biology. 13: 793-7. PMID 16936726 DOI: 10.1038/Nsmb1142  0.454
2006 Snøve O, Rossi JJ. Expressing short hairpin RNAs in vivo. Nature Methods. 3: 689-695. PMID 16929313 DOI: 10.1038/Nmeth927  0.452
2006 Benimetskaya L, Ayyanar K, Kornblum N, Castanotto D, Rossi J, Wu S, Lai J, Brown BD, Popova N, Miller P, McMicken H, Chen Y, Stein CA. Bcl-2 protein in 518A2 melanoma cells in vivo and in vitro. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4940-8. PMID 16914583 DOI: 10.1158/1078-0432.Ccr-06-1002  0.326
2006 Morris KV, Rossi JJ. Lentivirus-mediated RNA interference therapy for human immunodeficiency virus type 1 infection. Human Gene Therapy. 17: 479-86. PMID 16716105 DOI: 10.1089/Hum.2006.17.479  0.526
2006 Michienzi A, Angelis FGD, Bozzoni I, Rossi JJ. A nucleolar localizing Rev binding element inhibits HIV replication. Aids Research and Therapy. 3: 13-13. PMID 16712721 DOI: 10.1186/1742-6405-3-13  0.4
2006 Robbins MA, Li M, Leung I, Li H, Boyer DV, Song Y, Behlke MA, Rossi JJ. Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro. Nature Biotechnology. 24: 566-71. PMID 16648841 DOI: 10.1038/Nbt1206  0.455
2006 Rossi JJ. RNAi as a treatment for HIV-1 infection. Biotechniques. 40: 25-29. PMID 16629384 DOI: 10.2144/000112167  0.437
2006 Morris KV, Rossi JJ. Antiviral applications of RNAi. Current Opinion in Molecular Therapeutics. 8: 115-21. PMID 16610763 DOI: 10.1007/3-540-27262-3_6  0.467
2006 Unwalla HJ, Li HT, Bahner I, Li MJ, Kohn D, Rossi JJ. Novel Pol II fusion promoter directs human immunodeficiency virus type 1-inducible coexpression of a short hairpin RNA and protein Journal of Virology. 80: 1863-1873. PMID 16439542 DOI: 10.1128/Jvi.80.4.1863-1873.2006  0.441
2006 Morris KV, Rossi JJ. Lentiviral-mediated delivery of siRNAs for antiviral therapy Gene Therapy. 13: 553-558. PMID 16397511 DOI: 10.1038/Sj.Gt.3302688  0.498
2006 Weinberg MS, Villeneuve LM, Ehsani A, Amarzguioui M, Aagaard L, Chen ZX, Riggs AD, Rossi JJ, Morris KV. The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells. Rna (New York, N.Y.). 12: 256-62. PMID 16373483 DOI: 10.1261/Rna.2235106  0.451
2006 Morris K, Castanotto D, Al-Kadhimi Z, Jensen M, Rossi J, Cooper LJ. Enhancing siRNA effects in T cells for adoptive immunotherapy. Hematology (Amsterdam, Netherlands). 10: 461-7. PMID 16321811 DOI: 10.1080/10245330500233569  0.381
2006 Unwalla HJ, Rossi JJ. RNA interference as a potential antiviral Future Virology. 1: 501-508. DOI: 10.2217/17460794.1.4.501  0.482
2006 Krishnan AY, Zaia JA, Rossi JJ, Molina A, Li M, Lee W, Akkina R, Tsai N, Li S, Yam P, Li H, Yee J, Hsu D, Couture L, DiGiusto D, et al. Autologous Stem Cell Transplantation (ASCT) for AIDS-Related Lymphomas (ARL) and the Potential Role of HIV-Resistant Stem Cells. Blood. 108: 491-491. DOI: 10.1182/Blood.V108.11.491.491  0.462
2006 Trobridge GD, Beard BC, Dickerson D, Gooch C, Olsen P, Fletcher J, Li M, Hu S, Rossi JJ, Kiem H. Transduction of Macaque Hematopoietic Repopulating Cells with Lenti and Foamy Retroviral Vectors with MGMT Selection Cassettes To Evaluate AIDS Gene Therapy Strategies. Blood. 108: 3273-3273. DOI: 10.1182/Blood.V108.11.3273.3273  0.434
2006 Li S, Li H, Castanotto D, Meinking K, Sun G, Zaia JA, Rossi JJ. 810. Comparison of Anti-HIV Activity from Various Lentiviral Vectors Carrying Anti-HIV shRNA In Vitro Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.895  0.435
2006 Unwalla HJ, Seyhan AA, Johnston BH, Rossi JJ. 759. In Search of an Effective Target: In Vivo Approach Using HIV-1 Specific siRNA and Ribozyme Libraries Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.843  0.502
2005 Rossi JJ. Mammalian Dicer finds a partner Embo Reports. 6: 927-929. PMID 16222240 DOI: 10.1038/Sj.Embor.7400531  0.396
2005 Amarzguioui M, Rossi JJ, Kim D. Approaches for chemically synthesized siRNA and vector‐mediated RNAi Febs Letters. 579: 5974-5981. PMID 16199038 DOI: 10.1016/J.Febslet.2005.08.070  0.477
2005 Li MJ, Kim J, Li S, Zaia J, Yee JK, Anderson J, Akkina R, Rossi JJ. Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 900-9. PMID 16115802 DOI: 10.1016/J.Ymthe.2005.07.524  0.509
2005 Rose SD, Kim DH, Amarzguioui M, Heidel JD, Collingwood MA, Davis ME, Rossi JJ, Behlke MA. Functional polarity is introduced by Dicer processing of short substrate RNAs. Nucleic Acids Research. 33: 4140-56. PMID 16049023 DOI: 10.1093/Nar/Gki732  0.37
2005 Kim DH, Langlois M, Lee K, Riggs AD, Puymirat J, Rossi JJ. HnRNP H inhibits nuclear export of mRNA containing expanded CUG repeats and a distal branch point sequence Nucleic Acids Research. 33: 3866-3874. PMID 16027111 DOI: 10.1093/Nar/Gki698  0.379
2005 Li M, Rossi JJ. Lentiviral vector delivery of siRNA and shRNA encoding genes into cultured and primary hematopoietic cells. Methods in Molecular Biology (Clifton, N.J.). 309: 261-72. PMID 15990406 DOI: 10.1385/1-59259-935-4:261  0.443
2005 Castanotto D, Tommasi S, Li M, Li H, Yanow S, Pfeifer GP, Rossi JJ. Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 179-83. PMID 15963934 DOI: 10.1016/J.Ymthe.2005.03.003  0.385
2005 Strayer DS, Akkina R, Bunnell BA, Dropulic B, Planelles V, Pomerantz RJ, Rossi JJ, Zaia JA. Current status of gene therapy strategies to treat HIV/AIDS. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 823-42. PMID 15922953 DOI: 10.1016/J.Ymthe.2005.01.020  0.425
2005 Cook HL, Lytle JR, Mischo HE, Li MJ, Rossi JJ, Silva DP, Desrosiers RC, Steitz JA. Small nuclear RNAs encoded by Herpesvirus saimiri upregulate the expression of genes linked to T cell activation in virally transformed T cells. Current Biology : Cb. 15: 974-9. PMID 15916956 DOI: 10.1016/J.Cub.2005.04.034  0.367
2005 Gonzalez S, Castanotto D, Li H, Olivares S, Jensen MC, Forman SJ, Rossi JJ, Cooper LJ. Amplification of RNAi--targeting HLA mRNAs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 811-8. PMID 15851019 DOI: 10.1016/J.Ymthe.2004.12.023  0.48
2005 Rossi J. Helping RNAi Deliver Molecular Therapy. 11: 653. PMID 15851004 DOI: 10.1016/J.Ymthe.2005.03.013  0.319
2005 Robbins MA, Rossi JJ. Sensing the danger in RNA. Nature Medicine. 11: 250-1. PMID 15746933 DOI: 10.1038/Nm0305-250  0.339
2005 Heale BS, Soifer HS, Bowers C, Rossi JJ. siRNA target site secondary structure predictions using local stable substructures. Nucleic Acids Research. 33: e30. PMID 15722476 DOI: 10.1093/Nar/Gni026  0.324
2005 Langlois MA, Boniface C, Wang G, Alluin J, Salvaterra PM, Puymirat J, Rossi JJ, Lee NS. Cytoplasmic and nuclear retained DMPK mRNAs are targets for RNA interference in myotonic dystrophy cells. The Journal of Biological Chemistry. 280: 16949-54. PMID 15722335 DOI: 10.1074/Jbc.M501591200  0.463
2005 Soifer HS, Zaragoza A, Peyvan M, Behlke MA, Rossi JJ. A potential role for RNA interference in controlling the activity of the human LINE-1 retrotransposon. Nucleic Acids Research. 33: 846-56. PMID 15701756 DOI: 10.1093/Nar/Gki223  0.36
2005 Li M, Rossi JJ. Lentiviral vector delivery of recombinant small interfering RNA expression cassettes. Methods in Enzymology. 392: 218-226. PMID 15644184 DOI: 10.1016/S0076-6879(04)92013-7  0.456
2005 Kim D, Behlke MA, Rose SD, Chang M, Choi S, Rossi JJ. Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nature Biotechnology. 23: 222-226. PMID 15619617 DOI: 10.1038/Nbt1051  0.455
2005 Gu S, Rossi JJ. Uncoupling of RNAi from active translation in mammalian cells. Rna (New York, N.Y.). 11: 38-44. PMID 15574516 DOI: 10.1261/Rna.7158605  0.424
2005 Trobridge GD, Beagles K, Beard B, Li M, Yee J, Rossi J, Hu S, Kiem H. A Non-Human Primate Model To Study Anti-HIV Gene Therapy Strategies. Blood. 106: 3046-3046. DOI: 10.1182/Blood.V106.11.3046.3046  0.469
2005 Unwalla HJ, Bahner I, Li H, Li M, Kohn D, Rossi JJ, Gokhgauzer Y. 998. The HIV-1 LTR-hsp70 Fusion Promoter Directs HIV-1 Inducible Expression of Anti-Rev siRNA along with HIV-1 Rev Transdominant Mutant RevM10 Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.545  0.472
2005 Tarantal AF, Lee CI, Jimenez DF, Gambhir SS, Kohn DB, Rossi JJ, Cherry SR. 743. Lentiviral Vector Gene Transfer in Monkeys: In Vivo. Detection of Gene Expression Longitudinally Using MicroPET and Optical Imaging Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.283  0.324
2005 Beagles K, Trobridge G, Beard B, Rossi J, Yee J, Hu S, KIem H. 440. A Non-Human Primate Model for Lentivirus-Mediated Anti-HIV RNAi Strategies Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.448  0.478
2005 Roelvink PW, Graham MW, Suhy DA, Couto LB, Cunningham SM, Kay MA, Rossi JJ, Kolykhalov AA. 437. Alternative Strategies To Deliver Multiple shRNAs in Order to Simultaneously Inhibit Multiple Targets Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.445  0.456
2005 Ji J, Rossi JJ. 436. shRNAs Target HIV-1 Vif Gene Coding for SOCS-Box Motif Prevent Virus Escape from RNA Interference-Mediated Inhibition Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.444  0.434
2005 Li S, Wang G, Meinking K, Li MJ, Ji J, Zaia JA, Rossi JJ. 8. Potent Inhibition of HIV-1 Replication by Lentiviral Vectors Carrying Anti-Vif siRNA Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.011  0.494
2004 Banerjea A, Li M, Remling L, Rossi J, Akkina R. Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophages. Aids Research and Therapy. 1: 2-2. PMID 15813986 DOI: 10.1186/1742-6405-1-2  0.468
2004 Unwalla HJ, Li M, Kim JD, Li HT, Ehsani A, Alluin J, Rossi JJ. Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA Nature Biotechnology. 22: 1573-1578. PMID 15568018 DOI: 10.1038/Nbt1040  0.428
2004 Rossi JJ. Medicine: a cholesterol connection in RNAi. Nature. 432: 155-156. PMID 15538347 DOI: 10.1038/432155A  0.349
2004 Scherer L, Rossi JJ. Therapeutic applications of RNA interference: recent advances in siRNA design. Advances in Genetics. 52: 1-21. PMID 15522731 DOI: 10.1016/S0065-2660(04)52001-1  0.41
2004 Hannon GJ, Rossi JJ. Unlocking the potential of the human genome with RNA interference. Nature. 431: 371-8. PMID 15372045 DOI: 10.1038/Nature02870  0.403
2004 Scherer LJ, Yildiz Y, Kim J, Cagnon L, Heale B, Rossi JJ. Rapid assessment of anti-HIV siRNA efficacy using PCR-derived Pol III shRNA cassettes. Molecular Therapy. 10: 597-603. PMID 15336659 DOI: 10.1016/J.Ymthe.2004.05.003  0.48
2004 Scherer L, Rossi JJ. Recent applications of RNAi in mammalian systems. Current Pharmaceutical Biotechnology. 5: 355-360. PMID 15320766 DOI: 10.2174/1389201043376724  0.47
2004 Cordelier P, Kulkowsky JW, Ko C, Matskevitch AA, McKee HJ, Rossi JJ, Bouhamdan M, Pomerantz RJ, Kari G, Strayer DS. Protecting from R5-tropic HIV: individual and combined effectiveness of a hammerhead ribozyme and a single-chain Fv antibody that targets CCR5. Gene Therapy. 11: 1627-37. PMID 15295615 DOI: 10.1038/Sj.Gt.3302329  0.391
2004 Rossi JJ. Ribozyme Diagnostics Comes of Age Chemistry & Biology. 11: 894-895. PMID 15271347 DOI: 10.1016/J.Chembiol.2004.07.002  0.306
2004 Lu X, Yu Q, Binder GK, Chen Z, Slepushkina T, Rossi J, Dropulic B. Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance. Journal of Virology. 78: 7079-88. PMID 15194784 DOI: 10.1128/Jvi.78.13.7079-7088.2004  0.46
2004 Scherer L, Rossi JJ. RNAi Applications in Mammalian Cells Biotechniques. 36: 557-561. PMID 15088371 DOI: 10.2144/04364Te01  0.31
2004 Dwarakanath RS, Sahar S, Reddy MA, Castanotto D, Rossi JJ, Natarajan R. Regulation of monocyte chemoattractant protein-1 by the oxidized lipid, 13-hydroperoxyoctadecadienoic acid, in vascular smooth muscle cells via nuclear factor-kappa B (NF-kappa B). Journal of Molecular and Cellular Cardiology. 36: 585-95. PMID 15081318 DOI: 10.1016/J.Yjmcc.2004.02.007  0.324
2004 Morris KV, Rossi JJ. Anti-HIV-1 gene expressing lentiviral vectors as an adjunctive therapy for HIV-1 infection. Current Hiv Research. 2: 185-91. PMID 15078182 DOI: 10.2174/1570162043484906  0.475
2004 Lee NS, Rossi JJ. Control of HIV-1 replication by RNA interference Virus Research. 102: 53-58. PMID 15068880 DOI: 10.1016/J.Virusres.2004.01.015  0.508
2004 Song J, Lu YC, Yokoyama K, Rossi J, Chiu R. Cyclophilin A is required for retinoic acid-induced neuronal differentiation in p19 cells. The Journal of Biological Chemistry. 279: 24414-9. PMID 15047706 DOI: 10.1074/Jbc.M311406200  0.312
2004 Castanotto D, Rossi JJ. Construction and Transfection of PCR Products Expressing siRNAs or shRNAs in Mammalian Cells Methods of Molecular Biology. 252: 509-514. PMID 15017076 DOI: 10.1385/1-59259-746-7:509  0.439
2004 Chen H, Castanotto D, LeBon J, Rossi JJ, Riggs AD. In vivo detection of ribozyme cleavage products and RNA structure by use of terminal transferase-dependent PCR. Methods of Molecular Biology. 252: 109-123. PMID 15017045 DOI: 10.1385/1-59259-746-7:109  0.426
2004 Kim D, Longo M, Han Y, Lundberg P, Cantin E, Rossi JJ. Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase. Nature Biotechnology. 22: 321-325. PMID 14990954 DOI: 10.1038/Nbt940  0.423
2004 Beagles K, Beard B, Rossi J, Yee J, Hu S, Trobridge G, Kiem H. A Non-Human Primate Model for Lentivirus-Mediated Anti-HIV RNAi Strategies. Blood. 104: 3103-3103. DOI: 10.1182/Blood.V104.11.3103.3103  0.463
2004 Soifer HS, Vishwanath R, Kim J, Heale B, Scherer LJ, Rossi JJ. 548. Cyclophilin A as a cellular target for gene therapy of HIV-1 Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.500  0.48
2004 Weinberg M, Rossi JJ. 549. Nonconserved Sequence Motifs outside the Catalytic Core Improve the Trans-Splicing Efficiency of Anti-HIV Hammerhead Ribozymes Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.466  0.446
2004 Anderson JS, Banerjea A, Li M, Rossi J, Akkina R. 410. Multivalent siRNAs for Combinatorial HIV Gene Therapy Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.407  0.496
2004 Li M, Kim J, Li S, Zaia J, Yee J, Rossi JJ. 367. Development of Lentiviral Vectors Carrying shRNA, Ribozyme and RNA Decoy for the Inhibition of HIV-1 Infection Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.304  0.516
2004 Unwalla HJ, Kim JD, Li H, Rossi JJ. 366. Negative Feedback Inhibition of HIV-1: A Novel HIV-1 LTR-hsp70 Fusion Promoter Directs HIV-1 Inducible siRNA Expression Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.302  0.455
2003 Li MJ, McMahon R, Snyder DS, Yee JK, Rossi JJ. Specific killing of Ph+ chronic myeloid leukemia cells by a lentiviral vector-delivered anti-bcr/abl small hairpin RNA. Oligonucleotides. 13: 401-9. PMID 15000831 DOI: 10.1089/154545703322617087  0.305
2003 Michienzi A, Castanotto D, Lee N, Li S, Zaia JA, Rossi JJ. RNA-Mediated Inhibition of HIV in a Gene Therapy Setting Annals of the New York Academy of Sciences. 1002: 63-71. PMID 14751823 DOI: 10.1196/Annals.1281.008  0.462
2003 Scherer LJ, Rossi JJ. Approaches for the sequence-specific knockdown of mRNA. Nature Biotechnology. 21: 1457-1465. PMID 14647331 DOI: 10.1038/Nbt915  0.438
2003 Kim D, Rossi JJ. Coupling of RNAi-mediated target downregulation with gene replacement. Antisense & Nucleic Acid Drug Development. 13: 151-155. PMID 12954115 DOI: 10.1089/108729003768247619  0.433
2003 Li MJ, Bauer G, Michienzi A, Yee JK, Lee NS, Kim J, Li S, Castanotto D, Zaia J, Rossi JJ. Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 196-206. PMID 12907142 DOI: 10.1016/S1525-0016(03)00165-5  0.483
2003 Akkina R, Banerjea A, Bai J, Anderson J, Li MJ, Rossi J. siRNAs, ribozymes and RNA decoys in modeling stem cell-based gene therapy for HIV/AIDS. Anticancer Research. 23: 1997-2005. PMID 12894572  0.427
2003 Banerjea A, Li MJ, Bauer G, Remling L, Lee NS, Rossi J, Akkina R. Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages. Molecular Therapy. 8: 62-71. PMID 12842429 DOI: 10.1016/S1525-0016(03)00140-0  0.459
2003 Dohjima T, Lee NS, Li H, Ohno T, Rossi JJ. Small Interfering RNAs Expressed from a Pol III Promoter Suppress the EWS/Fli-1 Transcript in an Ewing Sarcoma Cell Line Molecular Therapy. 7: 811-816. PMID 12788655 DOI: 10.1016/S1525-0016(03)00101-1  0.412
2003 Langlois M, Lee NS, Rossi JJ, Puymirat J. Hammerhead ribozyme-mediated destruction of nuclear foci in myotonic dystrophy myoblasts. Molecular Therapy. 7: 670-680. PMID 12718910 DOI: 10.1016/S1525-0016(03)00068-6  0.387
2003 Paul CP, Good PD, Li SX, Kleihauer A, Rossi JJ, Engelke DR. Localized expression of small RNA inhibitors in human cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 237-47. PMID 12597912 DOI: 10.1016/S1525-0016(02)00038-2  0.49
2003 Michienzi A, Castanotto D, Lee N, Li S, Zaia JA, Rossi JJ. Novel ribozyme, RNA decoy, and siRNA approaches to inhibition of HIV in a gene therapy setting Clinical and Applied Immunology Reviews. 3: 223-233. DOI: 10.1016/S1529-1049(02)00155-1  0.444
2003 Scherer L, Rossi JJ. Recent applications of RNA interference (RNAi) in mammalian systems International Journal of Peptide Research and Therapeutics. 10: 255-267. DOI: 10.1007/S10989-004-4924-8  0.387
2003 Scherer L, Rossi JJ. Recent Applications of RNA Interference (RNAi) in Mammalian Systems Letters in Peptide Science. 10: 133-147. DOI: 10.1007/0-387-32956-0_8  0.476
2002 Bai J, Banda N, Lee NS, Rossi J, Akkina R. RNA-Based Anti-HIV-1 Gene Therapeutic Constructs in SCID-hu Mouse Model Molecular Therapy. 6: 770-782. PMID 12498773 DOI: 10.1006/Mthe.2002.0800  0.449
2002 Castanotto D, Li H, Rossi JJ. Functional siRNA expression from transfected PCR products. Rna. 8: 1454-1460. PMID 12458798 DOI: 10.1017/S1355838202021362  0.445
2002 Chang Z, Westaway S, Li S, Zaia JA, Rossi JJ, Scherer LJ. Enhanced expression and HIV- 1 inhition of chimeric tRNALys3-Ribozymes under dual U6 snRNA and tRNA promoters Molecular Therapy. 6: 481-489. PMID 12377189 DOI: 10.1006/Mthe.2002.0696  0.426
2002 Michienzi A, Li S, Zaia JA, Rossi JJ. A nucleolar TAR decoy inhibitor of HIV-1 replication Proceedings of the National Academy of Sciences of the United States of America. 99: 14047-14052. PMID 12376617 DOI: 10.1073/Pnas.212229599  0.457
2002 Hammond L, Castanotto D, Rice SR, Nimgaonkar VL, Wirshing DA, Rossi JJ, Heston LL, Sobell JL. Alteration of branch site consensus sequence and enhanced pre-mRNA splicing of an NMDAR1 intron not associated with schizophrenia. American Journal of Medical Genetics. 114: 631-6. PMID 12210277 DOI: 10.1002/Ajmg.10646  0.311
2002 Strayer D, Branco F, Zern MA, Yam P, Calarota SA, Nichols CN, Zaia JA, Rossi J, Li H, Parashar B, Ghosh S, Chowdhury JR. Durability of transgene expression and vector integration: recombinant SV40-derived gene therapy vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 227-37. PMID 12161189 DOI: 10.1006/Mthe.2002.0657  0.321
2002 Lee NS, Dohjima T, Bauer G, Li H, Li MJ, Ehsani A, Salvaterra P, Rossi J. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells Nature Biotechnology. 20: 500-505. PMID 11981565 DOI: 10.1038/Nbt0502-500  0.524
2001 Castanotto D, Li JR, Michienzi A, Langlois M-, Lee NS, Puymirat J, Rossi JJ. Intracellular ribozyme applications. Biochemical Society Transactions. 30: 1140-1145. PMID 12440991 DOI: 10.1042/Bst0301140  0.46
2001 Düzgünes N, Simões S, Konopka K, Rossi JJ, Pedroso de Lima MC. Delivery of novel macromolecular drugs against HIV-1. Expert Opinion On Biological Therapy. 1: 949-70. PMID 11728227 DOI: 10.1517/14712598.1.6.949  0.401
2001 Scherr M, LeBon J, Castanotto D, Cunliffe HE, Meltzer PS, Ganser A, Riggs AD, Rossi JJ. Detection of Antisense and Ribozyme Accessible Sites on Native mRNAs: Application to NCOA3 mRNA Molecular Therapy. 4: 454-460. PMID 11708882 DOI: 10.1006/Mthe.2001.0481  0.393
2001 Lee NS, Sun B, Williamson R, Gunkel N, Salvaterra PM, Rossi JJ. Functional colocalization of ribozymes and target mRNAs in Drosophila oocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2390-400. PMID 11689464 DOI: 10.1096/Fj.01-0116Com  0.422
2001 Düzgünes N, Simões S, Slepushkin V, Pretzer E, Rossi JJ, De Clercq E, Antao VP, Collins ML, de Lima MC. Enhanced inhibition of HIV-1 replication in macrophages by antisense oligonucleotides, ribozymes and acyclic nucleoside phosphonate analogs delivered in pH-sensitive liposomes. Nucleosides, Nucleotides & Nucleic Acids. 20: 515-23. PMID 11563068 DOI: 10.1081/Ncn-100002327  0.375
2001 Koehn RK, Rossi J, Stein CA. In defense of antisense. Science (New York, N.Y.). 293: 1047-8. PMID 11503637 DOI: 10.1126/Science.293.5532.1047  0.342
2001 Bai J, Rossi J, Akkina R. Multivalent Anti-CCR5 Ribozymes for Stem Cell-Based HIV Type 1 Gene Therapy Aids Research and Human Retroviruses. 17: 385-399. PMID 11282007 DOI: 10.1089/088922201750102427  0.462
2000 Wilkinson TA, Botuyan MV, Kaplan BE, Rossi JJ, Chen Y. Arginine side-chain dynamics in the HIV-1 rev-RRE complex. Journal of Molecular Biology. 303: 515-29. PMID 11054288 DOI: 10.1006/Jmbi.2000.4143  0.417
2000 Rossi JJ. Ribozyme therapy for HIV infection. Advanced Drug Delivery Reviews. 44: 71-78. PMID 11035199 DOI: 10.1016/S0169-409X(00)00085-5  0.4
2000 Konopka K, Lee NS, Rossi J, Düzgüneş N. Rev-binding aptamer and CMV promoter act as decoys to inhibit HIV replication. Gene. 255: 235-44. PMID 11024283 DOI: 10.1016/S0378-1119(00)00334-6  0.41
2000 Cagnon L, Rossi JJ. Downregulation of the CCR5 β-Chemokine Receptor and Inhibition of HIV-1 Infection by Stable VA1-Ribozyme Chimeric Transcripts Antisense & Nucleic Acid Drug Development. 10: 251-261. PMID 10984119 DOI: 10.1089/108729000421439  0.334
2000 Bai J, Gorantla S, Banda N, Cagnon L, Rossi J, Akkina R. Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo. Molecular Therapy. 1: 244-254. PMID 10933940 DOI: 10.1006/Mthe.2000.0038  0.366
2000 Michienzi A, Cagnon L, Bahner I, Rossi JJ. Ribozyme-mediated inhibition of HIV 1 suggests nucleolar trafficking of HIV-1 RNA Proceedings of the National Academy of Sciences of the United States of America. 97: 8955-8960. PMID 10922055 DOI: 10.1073/Pnas.97.16.8955  0.488
2000 Scherr M, Reed M, Huang C, Riggs AD, Rossi JJ. Oligonucleotide scanning of native mRNAs in extracts predicts intracellular ribozyme efficiency: ribozyme-mediated reduction of the murine DNA methyltransferase. Molecular Therapy. 2: 26-38. PMID 10899825 DOI: 10.1006/Mthe.2000.0091  0.425
2000 Scherr M, Rossi JJ, Sczakiel G, Patzel V. RNA accessibility prediction: a theoretical approach is consistent with experimental studies in cell extracts Nucleic Acids Research. 28: 2455-2461. PMID 10871393 DOI: 10.1093/Nar/28.13.2455  0.42
2000 Chen H, Castanotto D, LeBon JM, Rossi JJ, Riggs AD. In vivo, high-resolution analysis of yeast and mammalian RNA–protein interactions, RNA structure, RNA splicing and ribozyme cleavage by use of terminal transferase-dependent PCR Nucleic Acids Research. 28: 1656-1664. PMID 10710433 DOI: 10.1093/Nar/28.7.1656  0.399
2000 Castanotto D, Scherr M, Rossi JJ. Intracellular expression and function of antisense catalytic RNAs. Methods in Enzymology. 313: 401-420. PMID 10595369 DOI: 10.1016/S0076-6879(00)13025-3  0.488
1999 Wu Y, Yu L, McMahon R, Rossi JJ, Forman SJ, Snyder DS. Inhibition of bcr-abl oncogene expression by novel deoxyribozymes (DNAzymes). Human Gene Therapy. 10: 2847-57. PMID 10584930 DOI: 10.1089/10430349950016573  0.396
1999 Rossi JJ. Ribozymes in the nucleolus. Science. 285: 1685-1685. PMID 10523186 DOI: 10.1126/Science.285.5434.1685  0.438
1999 Kim D, Rossi JJ. The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex. Rna. 5: 959-971. PMID 10411139 DOI: 10.1017/S135583829999012X  0.325
1999 Browning CM, Cagnon L, Good PD, Rossi J, Engelke DR, Markovitz DM. Potent inhibition of human immunodeficiency virus type 1 (HIV-1) gene expression and virus production by an HIV-2 Tat activation-response RNA decoy Journal of Virology. 73: 5191-5195. PMID 10233987 DOI: 10.1128/Jvi.73.6.5191-5195.1999  0.434
1998 Rossi JJ. Therapeutic ribozymes: principles and applications. Biodrugs. 9: 1-10. PMID 18020552 DOI: 10.2165/00063030-199809010-00001  0.462
1998 Scherr M, Rossi JJ. Rapid determination and quantitation of the accessibility to native RNAs by antisense oligodeoxynucleotides in murine cell extracts Nucleic Acids Research. 26: 5079-5085. PMID 9801303 DOI: 10.1093/Nar/26.22.5079  0.387
1998 Pal BK, Scherer L, Zelby L, Bertrand E, Rossi JJ. Monitoring retroviral RNA dimerization in vivo via hammerhead ribozyme cleavage. Journal of Virology. 72: 8349-53. PMID 9733882 DOI: 10.1128/Jvi.72.10.8349-8353.1998  0.39
1998 Konopka K, Düzgüneş N, Rossi J, Lee NS. Receptor ligand-facilitated cationic liposome delivery of anti-HIV-1 Rev-binding aptamer and ribozyme DNAs. Journal of Drug Targeting. 5: 247-59. PMID 9713975 DOI: 10.3109/10611869808995879  0.422
1998 Westaway SK, Cagnon L, Chang Z, Li S, Li H, Larson GP, Zaia JA, Rossi JJ. Virion encapsidation of tRNA(3Lys)-ribozyme chimeric RNAs inhibits HIV infection. Antisense & Nucleic Acid Drug Development. 8: 185-97. PMID 9669656 DOI: 10.1089/Oli.1.1998.8.185  0.486
1998 Konopka K, Rossi JJ, Swiderski P, Slepushkin VA, Düzgüneş N. Delivery of an anti-HIV-1 ribozyme into HIV-infected cells via cationic liposomes. Biochimica Et Biophysica Acta. 1372: 55-68. PMID 9651480 DOI: 10.1016/S0005-2736(98)00046-7  0.349
1998 Kechli AM, Freiden PJ, Rossi JJ, Brenner MK, Choueiry MA, Garcia JV, Slobod KS. Expression of the human immunodeficiency virus type 1 primer binding sequence inhibits HIV-1 replication Human Gene Therapy. 9: 587-590. PMID 9525319 DOI: 10.1089/Hum.1998.9.4-587  0.433
1998 Castanotto D, Li H, Chow W, Rossi JJ, Deshler JO. Structural similarities between hammerhead ribozymes and the spliceosomal RNAs could be responsible for lack of ribozyme cleavage in yeast. Antisense & Nucleic Acid Drug Development. 8: 1-13. PMID 9512091 DOI: 10.1089/Oli.1.1998.8.1  0.433
1998 Rossi JJ. Therapeutic applications of catalytic antisense RNAs (ribozymes). Ciba Foundation Symposium. 209: 195-204; discussion . PMID 9383577 DOI: 10.1002/9780470515396.CH14  0.335
1997 Cagnon L, Rossi J. Retroviral Delivery and Anti-HIV Testing of Hammerhead Ribozymes Methods of Molecular Biology. 74: 451-457. PMID 9204460 DOI: 10.1385/0-89603-389-9:451  0.366
1997 Lee NS, Bertrand E, Rossi JJ. Enhancement of ribozyme function by RNA binding proteins. Methods of Molecular Biology. 74: 275-279. PMID 9204442 DOI: 10.1385/0-89603-389-9:275  0.369
1997 Gu J, Nadler J, Rossi J. Use of a hammerhead ribozyme with cationic liposomes to reduce leukocyte type 12-lipoxygenase expression in vascular smooth muscle. Molecular and Cellular Biochemistry. 172: 47-57. DOI: 10.1007/978-1-4615-6353-2_5  0.436
1996 Heidenreich O, Xu X, Swiderski P, Rossi JJ, Nerenberg M. Correlation of Activity with Stability of Chemically Modified Ribozymes in Nuclei Suspension Antisense & Nucleic Acid Drug Development. 6: 111-118. PMID 8843325 DOI: 10.1089/Oli.1.1996.6.111  0.347
1996 Zhou C, Bahner I, Rossi JJ, Kohn DB. Expression of Hammerhead Ribozymes by Retroviral Vectors to Inhibit HIV-1 Replication: Comparison of RNA Levels and Viral Inhibition Antisense & Nucleic Acid Drug Development. 6: 17-24. PMID 8783792 DOI: 10.1089/Oli.1.1996.6.17  0.449
1995 Deshler JO, Li H, Rossi JJ, Castanotto D. Ribozymes expressed within the loop of a natural antisense RNA form functional transcription terminators. Gene. 155: 35-43. PMID 7698665 DOI: 10.1016/0378-1119(94)00889-Z  0.439
1995 Heidenreich O, Kang SH, Brown DA, Xu X, Swiderski P, Rossi JJ, Eckstein F, Nerenberg M. Ribozyme-mediated RNA degradation in nuclei suspension Nucleic Acids Research. 23: 2223-2228. PMID 7610051 DOI: 10.1093/Nar/23.12.2223  0.428
1995 Rossi JJ. Controlled, targeted, intracellular expression of ribozymes: progress and problems Trends in Biotechnology. 13: 301-306. PMID 7544984 DOI: 10.1016/S0167-7799(00)88969-6  0.352
1995 Gu JL, Veerapanane D, Rossi J, Natarajan R, Thomas L, Nadler J. Ribozyme-mediated inhibition of expression of leukocyte-type 12-lipoxygenase in porcine aortic vascular smooth muscle cells. Circulation Research. 77: 14-20. PMID 7540514 DOI: 10.1161/01.Res.77.1.14  0.369
1995 Konopka K, Rossi JJ, Felgner P, Düzgünes N. Cationic liposome-mediated delivery of anti-HIV-1 ribozyme to chronically infected cells Antiviral Research. 26. DOI: 10.1016/0166-3542(95)94773-U  0.377
1994 Gu JL, Natarajan R, Ben-Ezra J, Valente G, Scott S, Yoshimoto T, Yamamoto S, Rossi JJ, Nadler JL. Evidence that a leukocyte type of 12-lipoxygenase is expressed and regulated by angiotensin II in human adrenal glomerulosa cells. Endocrinology. 134: 70-7. PMID 8275971 DOI: 10.1210/Endo.134.1.8275971  0.332
1994 Castanotto D, Rossi JJ, Sarver N. Antisense catalytic RNAs as therapeutic agents. Advances in Pharmacology (San Diego). 25: 289-317. PMID 8204504 DOI: 10.1016/S1054-3589(08)60435-4  0.369
1994 Elkins DA, Torabinejad M, Schmidt RE, Rossi JJ, Kettering JD. Polymerase chain reaction detection of human immunodeficiency virus DNA in human periradicular lesions Journal of Endodontics. 20: 386-388. PMID 7996105 DOI: 10.1016/S0099-2399(06)80296-7  0.356
1994 Chen Z, Bahner IC, Larson GP, Zaia JA, Rossi JJ, Kohn DB. Inhibition of HIV-1 in human T-lymphocytes by retrovirally transduced anti-tat and rev hammerhead ribozymes Gene. 149: 33-39. PMID 7958986 DOI: 10.1016/0378-1119(94)90409-X  0.505
1994 Rossi JJ. Practical Ribozymes: Making ribozymes work in cells Current Biology. 4: 469-471. PMID 7522917 DOI: 10.1016/S0960-9822(00)00106-8  0.395
1994 Bertrand EL, Rossi JJ. Facilitation of hammerhead ribozyme catalysis by the nucleocapsid protein of HIV-1 and the heterogeneous nuclear ribonucleoprotein A1. The Embo Journal. 13: 2904-2912. DOI: 10.1002/J.1460-2075.1994.Tb06585.X  0.303
1993 Dropulic B, Elkins DA, Rossi JJ, Sarver N. Ribozymes: Use as Anti-HIV therapeutic molecules Antisense Research and Development. 3: 87-94. PMID 8495108 DOI: 10.1089/Ard.1993.3.87  0.365
1993 Sarver N, Rossi J. Gene Therapy: A Bold Direction for HIV-1 Treatment* Aids Research and Human Retroviruses. 9: 483-487. PMID 8391287 DOI: 10.1089/Aid.1993.9.483  0.374
1993 Snyder DS, Wu Y, Wang JL, Rossi JJ, Swiderski P, Kaplan BE, Forman SJ. Ribozyme-mediated inhibition of bcr-abl gene expression in a Philadelphia chromosome-positive cell line. Blood. 82: 600-605. DOI: 10.1182/Blood.V82.2.600.600  0.378
1993 Larson GP, Bertrand E, Rossi JJ. Designing and Testing of Ribozymes as Therapeutic Agents Methods. 5: 19-27. DOI: 10.1006/Meth.1993.1003  0.41
1993 Rossi JJ. Editorial: Introductory Remarks on the General Application of Antisense RNAs and Ribozymes Methods. 5: 1-5. DOI: 10.1006/Meth.1993.1001  0.4
1992 Rossi JJ, Elkins D, Zaia JA, Sullivan S. Ribozymes as anti-HIV-1 therapeutic agents: Principles, applications, and problems Aids Research and Human Retroviruses. 8: 183-189. PMID 1540406 DOI: 10.1089/Aid.1992.8.183  0.493
1992 Rossi JJ, Sarver N. Catalytic Antisense RNA (Ribozymes): Their Potential and Use as ANTI-HIV-1 Therapeutic Agents Advances in Experimental Medicine and Biology. 312: 95-109. PMID 1514448 DOI: 10.1007/978-1-4615-3462-4_9  0.47
1992 Arnold BL, Itakura K, Rossi JJ. PCR-based quantitation of low levels of HIV-1 DNA by using an external standard Genetic Analysis Techniques and Applications. 9: 113-116. PMID 1472386 DOI: 10.1016/1050-3862(92)90050-F  0.324
1992 McCarrey JR, Berg WM, Paragioudakis SJ, Zhang PL, Dilworth DD, Arnold BL, Rossi JJ. Differential transcription of Pgk genes during spermatogenesis in the mouse Developmental Biology. 154: 160-168. PMID 1426623 DOI: 10.1016/0012-1606(92)90056-M  0.344
1992 Taylor NR, Kaplan BE, Swiderski P, Li H, Rossi JJ. Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo. Nucleic Acids Research. 20: 4559-65. PMID 1408757 DOI: 10.1093/Nar/20.17.4559  0.45
1992 Zaia JA, Chatterjee S, Wong KK, Elkins D, Taylor NR, Rossi JJ. Status of ribozyme and antisense-based developmental approaches for anti-HIV-1 therapy. Annals of the New York Academy of Sciences. 660: 95-106. PMID 1340161 DOI: 10.1111/J.1749-6632.1992.Tb21062.X  0.374
1991 Larson GP, Rossi JJ. Altered response to growth rate changes in Kluyveromyces lactis versus Saccharomyces cerevisiae as demonstrated by heterologous expression of ribosomal protein 59 { CRY1 ) Nucleic Acids Research. 19: 4701-4707. PMID 1891361 DOI: 10.1093/Nar/19.17.4701  0.326
1991 Chrisey L, Rossi J, Sarver N. Meeting Report. Ribozymes: progress and prospects of catalytic RNA as therapeutic agents. Antisense Research and Development. 1: 57-63. PMID 1822249 DOI: 10.1089/Ard.1991.1.57  0.401
1991 Rossi JJ, Cantin EM, Sarver N, Chang PF. The potential use of catalytic RNAs in therapy of HIV infection and other diseases. Pharmacology & Therapeutics. 50: 245-254. PMID 1763136 DOI: 10.1016/0163-7258(91)90016-F  0.418
1991 Taylor NR, Rossi JJ. Ribozyme-mediated cleavage of an HIV-1 gag RNA: the effects of nontargeted sequences and secondary structure on ribozyme cleavage activity. Antisense Research and Development. 1: 173-86. PMID 1726777 DOI: 10.1089/Ard.1991.1.173  0.488
1991 Ben-Ezra J, Johnson DA, Rossi J, Cook N, Wu A. Effect of fixation on the amplification of nucleic acids from paraffin-embedded material by the polymerase chain reaction. Journal of Histochemistry and Cytochemistry. 39: 351-354. PMID 1704393 DOI: 10.1177/39.3.1704393  0.312
1991 Scanlon KJ, Jiao L, Funato T, Wang W, Tone T, Rossi JJ, Kashani-Sabet M. Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein Proceedings of the National Academy of Sciences of the United States of America. 88: 10591-10595. PMID 1660142 DOI: 10.1073/Pnas.88.23.10591  0.336
1991 ROSSI JJ, ELKINS D, TAYLOR N, ZAIA J, SULLIVAN S, DESHLER JO. Exploring the Use of Antisense, Enzymatic RNA Molecules (Ribozymes) as Therapeutic Agents Antisense Research and Development. 1: 285-288. DOI: 10.1089/Ard.1991.1.285  0.457
1990 Sarver N, Cantin EM, Chang PS, Zaia JA, Ladne PA, Stephens DA, Rossi JJ. Ribozymes as potential anti-HIV-1 therapeutic agents Science. 247: 1222-1225. PMID 2107573 DOI: 10.1126/Science.2107573  0.498
1990 Rossi JJ, Sarver N. RNA enzymes (ribozymes) as antiviral therapeutic agents Trends in Biotechnology. 8: 179-183. PMID 1366622 DOI: 10.1016/0167-7799(90)90169-X  0.439
1990 Sarver N, Hampel A, Cantin EM, Zaia JA, Chang PS, Johnston MI, McGOWAN J, Rossi JJ. Self‐Cleaving RNAs (Ribozymes) as New Modalities for Anti‐HIV Therapy Annals of the New York Academy of Sciences. 616: 606-609. DOI: 10.1111/J.1749-6632.1990.Tb17905.X  0.389
1989 Zaia JA, Rossi JJ. Confirmation of HIV infection using gene amplification Transfusion Medicine Reviews. 3: 27-30. PMID 2520545 DOI: 10.1016/S0887-7963(89)70233-9  0.462
1988 Murakawa GJ, Zaia JA, Spallone PA, Stephens DA, Kaplan BE, Wallace RB, Rossi JJ. Direct detection of HIV-1 RNA from AIDS and ARC patient samples Dna. 7: 287-295. PMID 3396453 DOI: 10.1089/dna.1988.7.287  0.33
1988 Zaia JA, Rossi JJ, Murakawa GJ, Spallone PA, Stephens DA, Kaplan BE, Eritja R, Wallace RB, Cantin EM. Inhibition of human immunodeficiency virus by using an oligonucleoside methylphosphonate targeted to the tat-3 gene. Journal of Virology. 62: 3914-7. PMID 2458490 DOI: 10.1128/Jvi.62.10.3914-3917.1988  0.468
1987 Felder E, Cellini A, Rossi J. Oligonucleotide mediated mutational analysis of recognition sequence effects on lariat formation during messenger rna splicing in yeast Nucleosides and Nucleotides. 6: 409-411. DOI: 10.1080/07328318708056240  0.335
1986 Cellini A, Felder E, Rossi JJ. Yeast pre-messenger RNA splicing efficiency depends on critical spacing requirements between the branch point and 3' splice site. The Embo Journal. 5: 1023-1030. DOI: 10.1002/J.1460-2075.1986.Tb04317.X  0.349
1985 Ng R, Domdey H, Larson G, Rossi JJ, Abelson J. A test for intron function in the yeast actin gene. Nature. 314: 183-184. PMID 3883197 DOI: 10.1038/314183A0  0.325
1983 Rossi JJ, Schold M, Larson GP, Wallace RB. Functional expression of a yeast ochre suppressor tRNA gene in Escherichia coli. Gene. 20: 423-32. PMID 6819979 DOI: 10.1016/0378-1119(82)90211-6  0.339
1983 Larson GP, Itakura K, Ito H, Rossi JJ. Saccharomyces cerevisiae actin--Escherichia coli lacZ gene fusions: synthetic-oligonucleotide-mediated deletion of the 309 base pair intervening sequence in the actin gene. Gene. 22: 31-39. PMID 6407898 DOI: 10.1016/0378-1119(83)90061-6  0.328
1983 Rossi JJ, Soberon X, Marumoto Y, McMahon J, Itakura K. Biological expression of an Escherichia coli consensus sequence promoter and some mutant derivatives. Proceedings of the National Academy of Sciences of the United States of America. 80: 3203-3207. PMID 6304698 DOI: 10.1073/Pnas.80.11.3203  0.381
1982 Reilly JG, Ogden R, Rossi JJ. Isolation of a mouse pseudo tRNA gene encoding CCA—a possible example of reverse flow of genetic information Nature. 300: 287-289. PMID 6924072 DOI: 10.1038/300287A0  0.356
1981 Hudson L, Rossi J, Landy A. Dual function transcripts specifying tRNA and mRNA. Nature. 294: 422-7. PMID 7312036 DOI: 10.1038/294422A0  0.587
1981 Rossi J, Egan J, Hudson L, Landy A. The tyrT locus: termination and processing of a complex transcript. Cell. 26: 305-14. PMID 7034960 DOI: 10.1016/0092-8674(81)90199-9  0.534
1980 Rossi J, Egan J, Berman ML, Landy A. Escherichia coli tRNA Tyr Gene Clusters: Organization and Structure Cold Spring Harbor Monograph Archive. 221-244. DOI: 10.1101/087969129.9B.221  0.494
1979 Rossi JJ, Landy A. Structure and organization of the two tRNATyr gene clusters on the E. coli chromosome. Cell. 16: 523-34. PMID 378394 DOI: 10.1016/0092-8674(79)90027-8  0.519
1979 Rossi JJ, Ross W, Egan J, Lipman DJ, Landy A. Structural organization of Escherichia coli tRNAtyr gene clusters in four different transducing bacteriophages. Journal of Molecular Biology. 128: 21-47. PMID 372548 DOI: 10.1016/0022-2836(79)90307-3  0.55
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