Derek P Narendra - Publications

Affiliations: 
NIH, NINDS 
Area:
Mitochondrial biology, Parkinson's disease, Neurodegeneration, Autophagy

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lin HP, Petersen JD, Gilsrud AJ, Madruga A, D'Silva TM, Huang X, Shammas MK, Randolph NP, Li Y, Jones DR, Pacold ME, Narendra DP. DELE1 promotes translation-associated homeostasis, growth, and survival in mitochondrial myopathy. Biorxiv : the Preprint Server For Biology. PMID 38529505 DOI: 10.1101/2024.02.29.582673  0.557
2023 Shammas MK, Nie Y, Gilsrud A, Huang X, Narendra DP, Chinnery PF. CHCHD10 mutations induce tissue-specific mitochondrial DNA deletions with a distinct signature. Human Molecular Genetics. PMID 37815936 DOI: 10.1093/hmg/ddad161  0.418
2023 Sekine Y, Houston R, Eckl EM, Fessler E, Narendra DP, Jae LT, Sekine S. A mitochondrial iron-responsive pathway regulated by DELE1. Molecular Cell. 83: 2059-2076.e6. PMID 37327776 DOI: 10.1016/j.molcel.2023.05.031  0.415
2023 Shammas MK, Huang TH, Narendra DP. CHCHD2 and CHCHD10-related neurodegeneration: molecular pathogenesis and the path to precision therapy. Biochemical Society Transactions. 51: 797-809. PMID 37021679 DOI: 10.1042/BST20221365  0.426
2022 Shammas MK, Huang X, Wu BP, Fessler E, Song I, Randolph NP, Li Y, Bleck CK, Springer DA, Fratter C, Barbosa IA, Powers AF, Quirós PM, Lopez-Otin C, Jae LT, ... ... Narendra DP, et al. OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy. The Journal of Clinical Investigation. PMID 35700042 DOI: 10.1172/JCI157504  0.48
2021 Narendra DP. Managing risky assets - mitophagy in vivo. Journal of Cell Science. 134. PMID 34612485 DOI: 10.1242/jcs.240465  0.481
2021 Houston R, Sekine Y, Larsen MB, Murakami K, Mullett SJ, Wendell SG, Narendra DP, Chen BB, Sekine S. Discovery of bactericides as an acute mitochondrial membrane damage inducer. Molecular Biology of the Cell. mbcE21040191. PMID 34495738 DOI: 10.1091/mbc.E21-04-0191  0.55
2020 Malpartida AB, Williamson M, Narendra DP, Wade-Martins R, Ryan BJ. Mitochondrial Dysfunction and Mitophagy in Parkinson's Disease: From Mechanism to Therapy. Trends in Biochemical Sciences. PMID 33323315 DOI: 10.1016/j.tibs.2020.11.007  0.488
2020 Calvelli H, Krigman J, Onishi M, Narendra DP, Sun N, Okamoto K. Detection of mitophagy in mammalian cells, mice, and yeast. Methods in Cell Biology. 155: 557-579. PMID 32183977 DOI: 10.1016/bs.mcb.2019.10.006  0.445
2018 Huang X, Wu BP, Nguyen D, Liu YT, Marani M, Hench J, Bénit P, Kozjak-Pavlovic V, Rustin P, Frank S, Narendra DP. CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10. Human Molecular Genetics. PMID 30285108 DOI: 10.1093/hmg/ddy340  0.544
2018 Sliter DA, Martinez J, Hao L, Chen X, Sun N, Fischer TD, Burman JL, Li Y, Zhang Z, Narendra DP, Cai H, Borsche M, Klein C, Youle RJ. Parkin and PINK1 mitigate STING-induced inflammation. Nature. PMID 30135585 DOI: 10.1038/S41586-018-0448-9  0.677
2018 Huang X, Wu BP, Nguyen D, Liu YT, Marani M, Hench J, Bénit P, Kozjak-Pavlovic V, Rustin P, Frank S, Narendra DP. CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10. Human Molecular Genetics. PMID 30084972 DOI: 10.1093/hmg/ddy270  0.517
2013 Narendra DP, Wang C, Youle RJ, Walker JE. PINK1 rendered temperature sensitive by disease-associated and engineered mutations. Human Molecular Genetics. 22: 2572-89. PMID 23459931 DOI: 10.1093/Hmg/Ddt106  0.713
2013 Lazarou M, Narendra DP, Jin SM, Tekle E, Banerjee S, Youle RJ. PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding. The Journal of Cell Biology. 200: 163-72. PMID 23319602 DOI: 10.1083/Jcb.201210111  0.713
2012 Narendra D, Walker JE, Youle R. Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism. Cold Spring Harbor Perspectives in Biology. 4. PMID 23125018 DOI: 10.1101/Cshperspect.A011338  0.77
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Narendra DP, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.471
2012 Narendra DP, Youle RJ. Neurodegeneration: Trouble in the cell's powerhouse. Nature. 483: 418-9. PMID 22398449 DOI: 10.1038/Nature10952  0.497
2011 Narendra DP, Youle RJ. Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control. Antioxidants & Redox Signaling. 14: 1929-38. PMID 21194381 DOI: 10.1089/Ars.2010.3799  0.748
2011 Youle RJ, Narendra DP. Mechanisms of mitophagy. Nature Reviews. Molecular Cell Biology. 12: 9-14. PMID 21179058 DOI: 10.1038/Nrm3028  0.593
2010 Tanaka A, Cleland MM, Xu S, Narendra DP, Suen DF, Karbowski M, Youle RJ. Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. The Journal of Cell Biology. 191: 1367-80. PMID 21173115 DOI: 10.1083/Jcb.201007013  0.736
2010 Jin SM, Lazarou M, Wang C, Kane LA, Narendra DP, Youle RJ. Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. The Journal of Cell Biology. 191: 933-42. PMID 21115803 DOI: 10.1083/Jcb.201008084  0.742
2010 Narendra DP, Kane LA, Hauser DN, Fearnley IM, Youle RJ. p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both Autophagy. 6: 1090-1106. PMID 20890124 DOI: 10.4161/Auto.6.8.13426  0.715
2010 Suen DF, Narendra DP, Tanaka A, Manfredi G, Youle RJ. Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 11835-40. PMID 20547844 DOI: 10.1073/Pnas.0914569107  0.706
2010 Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, Shen J, Cookson MR, Youle RJ. PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. Plos Biology. 8: e1000298. PMID 20126261 DOI: 10.1371/Journal.Pbio.1000298  0.742
2009 Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin-induced mitophagy in the pathogenesis of Parkinson disease. Autophagy. 5: 706-8. PMID 19377297 DOI: 10.4161/Auto.5.5.8505  0.721
2008 Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. The Journal of Cell Biology. 183: 795-803. PMID 19029340 DOI: 10.1083/Jcb.200809125  0.748
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