Lee Eiden, Ph.D. - Publications

Affiliations: 
Section on Molecular Neuroscience National Institute of Mental Health, Bethesda, MD, United States 
Area:
stress, vesicles, neuropeptides, GPCR's
Website:
http://www.nimh.nih.gov/labs-at-nimh/principal-investigators/lee-eiden.shtml

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Eiden LE, Emery AC, Dahlke S, Xu W. Persistence of Cyclic AMP Signaling Determines Gs‐couple GPCR Linkage to ERK Activation The Faseb Journal. 34: 1-1. DOI: 10.1096/fasebj.2020.34.s1.07141  0.714
2015 Emery AC, Liu XH, Xu W, Eiden MV, Eiden LE. Cyclic Adenosine 3',5'-Monophosphate Elevation and Biological Signaling through a Secretin Family Gs-Coupled G Protein-Coupled Receptor Are Restricted to a Single Adenylate Cyclase Isoform. Molecular Pharmacology. 87: 928-35. PMID 25769305 DOI: 10.1124/mol.115.098087  0.737
2015 Mustafa T, Jiang SZ, Eiden AM, Weihe E, Thistlethwaite I, Eiden LE. Impact of PACAP and PAC1 receptor deficiency on the neurochemical and behavioral effects of acute and chronic restraint stress in male C57BL/6 mice Stress. 18: 408-418. DOI: 10.3109/10253890.2015.1025044  0.609
2014 Seaborn T, Ravni A, Au R, Chow BK, Fournier A, Wurtz O, Vaudry H, Eiden LE, Vaudry D. Induction of serpinb1a by PACAP or NGF is required for PC12 cells survival after serum withdrawal. Journal of Neurochemistry. 131: 21-32. PMID 24899316 DOI: 10.1111/Jnc.12780  0.343
2014 Emery AC, Eiden MV, Eiden LE. Separate cyclic AMP sensors for neuritogenesis, growth arrest, and survival of neuroendocrine cells. The Journal of Biological Chemistry. 289: 10126-39. PMID 24567337 DOI: 10.1074/jbc.M113.529321  0.737
2013 Emery AC, Eiden MV, Mustafa T, Eiden LE. Rapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cells. Science Signaling. 6: ra51. PMID 23800469 DOI: 10.1126/scisignal.2003993  0.74
2013 Emery AC, Eiden MV, Eiden LE. A new site and mechanism of action for the widely used adenylate cyclase inhibitor SQ22,536. Molecular Pharmacology. 83: 95-105. PMID 23053667 DOI: 10.1124/mol.112.081760  0.738
2013 Emery AC, Eiden LE. Novel cAMP Sensor Links GPCR-Gs Signaling to ERK in Neuroscreen-1 Cells Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 114. DOI: 10.1016/B978-0-12-800044-1.00100-8  0.711
2012 Emery AC, Eiden LE. Signaling through the neuropeptide GPCR PAC₁ induces neuritogenesis via a single linear cAMP- and ERK-dependent pathway using a novel cAMP sensor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3199-211. PMID 22532442 DOI: 10.1096/fj.11-203042  0.738
2012 Bunn SJ, Ait-Ali D, Eiden LE. Immune-neuroendocrine integration at the adrenal gland: cytokine control of the adrenomedullary transcriptome. Journal of Molecular Neuroscience : Mn. 48: 413-9. PMID 22421803 DOI: 10.1007/s12031-012-9745-1  0.322
2012 Holighaus Y, Weihe E, Eiden LE. STC1 induction by PACAP is mediated through cAMP and ERK1/2 but not PKA in cultured cortical neurons Journal of Molecular Neuroscience. 46: 75-87. PMID 21975601 DOI: 10.1007/s12031-011-9653-9  0.43
2011 Holighaus Y, Mustafa T, Eiden LE. PAC1hop, null and hip receptors mediate differential signaling through cyclic AMP and calcium leading to splice variant-specific gene induction in neural cells Peptides. 32: 1647-1655. PMID 21693142 DOI: 10.1016/j.peptides.2011.06.004  0.412
2008 Eiden LE, Samal B, Gerdin MJ, Mustafa T, Vaudry D, Stroth N. Discovery of pituitary adenylate cyclase-activating polypeptide-regulated genes through microarray analyses in cell culture and in vivo Annals of the New York Academy of Sciences. 1144: 6-20. PMID 19076358 DOI: 10.1196/annals.1418.019  0.357
2008 Samal BB, Eiden LE. pathFinder: A static network analysis tool for pharmacological analysis of signal transduction pathways Science Signaling. 1. PMID 18682604 DOI: 10.1126/scisignal.131pt4  0.308
2008 Ravni A, Vaudry D, Gerdin MJ, Eiden MV, Falluel-Morel A, Gonzalez BJ, Vaudry H, Eiden LE. A cAMP-dependent, protein kinase A-independent signaling pathway mediating neuritogenesis through Egr1 in PC12 cells Molecular Pharmacology. 73: 1688-1708. PMID 18362103 DOI: 10.1124/mol.107.044792  0.441
2007 Gerdin MJ, Eiden LE. Regulation of PC12 cell differentiation by cAMP signaling to ERK independent of PKA: do all the connections add up? Science's Stke : Signal Transduction Knowledge Environment. 2007: pe15. PMID 17440132 DOI: 10.1126/stke.3822007pe15  0.453
2006 Chen Y, Samal B, Hamelink CR, Xiang CC, Chen Y, Chen M, Vaudry D, Brownstein MJ, Hallenbeck JM, Eiden LE. Neuroprotection by endogenous and exogenous PACAP following stroke. Regulatory Peptides. 137: 4-19. PMID 17027094 DOI: 10.1016/j.regpep.2006.06.016  0.533
2006 Ravni A, Bourgault S, Lebon A, Chan P, Galas L, Fournier A, Vaudry H, Gonzalez B, Eiden LE, Vaudry D. The neurotrophic effects of PACAP in PC12 cells: control by multiple transduction pathways. Journal of Neurochemistry. 98: 321-9. PMID 16805827 DOI: 10.1111/J.1471-4159.2006.03884.X  0.319
2004 Ait-Ali D, Turquier V, Grumolato L, Yon L, Jourdain M, Alexandre D, Eiden LE, Vaudry H, Anouar Y. The proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1 stimulate neuropeptide gene transcription and secretion in adrenochromaffin cells via activation of extracellularly regulated kinase 1/2 and p38 protein kinases, and activator protein-1 transcription factors. Molecular Endocrinology (Baltimore, Md.). 18: 1721-39. PMID 15087472 DOI: 10.1210/Me.2003-0129  0.576
2003 Hahm SH, Chen Y, Vinson C, Eiden LE. A Calcium-Initiated Signaling Pathway Propagated through Calcineurin and cAMP Response Element-Binding Protein Activates Proenkephalin Gene Transcription after Depolarization Molecular Pharmacology. 64: 1503-1511. PMID 14645681 DOI: 10.1124/mol.64.6.1503  0.373
2003 Grumolato L, Elkahloun AG, Ghzili H, Alexandre D, Coulouarn C, Yon L, Salier JP, Eiden LE, Fournier A, Vaudry H, Anouar Y. Microarray and suppression subtractive hybridization analyses of gene expression in pheochromocytoma cells reveal pleiotropic effects of pituitary adenylate cyclase-activating polypeptide on cell proliferation, survival, and adhesion. Endocrinology. 144: 2368-79. PMID 12746297 DOI: 10.1210/En.2002-0106  0.53
2002 Vaudry D, Chen Y, Ravni A, Hamelink C, Elkahloun AG, Eiden LE. Analysis of the PC12 cell transcriptome after differentiation with pituitary adenylate cyclase-activating polypeptide (PACAP) Journal of Neurochemistry. 83: 1272-1284. PMID 12472882 DOI: 10.1046/j.1471-4159.2002.01242.x  0.341
2002 Hamelink C, Lee HW, Hsu CM, Eiden LE. Role of protein kinases in neuropeptide gene regulation by PACAP in chromaffin cells: A pharmacological and bioinformatic analysis Annals of the New York Academy of Sciences. 971: 474-490. PMID 12438168  0.402
2002 Vaudry D, Stork PJ, Lazarovici P, Eiden LE. Signaling pathways for PC12 cell differentiation: making the right connections. Science (New York, N.Y.). 296: 1648-9. PMID 12040181 DOI: 10.1126/science.1071552  0.382
2002 Hamelink C, Tjurmina O, Damadzic R, Young WS, Weihe E, Lee HW, Eiden LE. Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis. Proceedings of the National Academy of Sciences of the United States of America. 99: 461-6. PMID 11756684 DOI: 10.1073/pnas.012608999  0.51
1999 Anouar Y, Lee HW, Eiden LE. Both inducible and constitutive activator protein-1-like transcription factors are used for transcriptional activation of the galanin gene by different first and second messenger pathways Molecular Pharmacology. 56: 162-169. PMID 10385697  0.344
1996 MacArthur L, Eiden L. Neuropeptide genes: targets of activity-dependent signal transduction. Peptides. 17: 721-8. PMID 8804085 DOI: 10.1016/0196-9781(95)02100-0  0.372
1993 MacArthur L, Koller KJ, Eiden LE. Enkephalin gene transcription in bovine chromaffin cells is regulated by calcium and protein kinase A signal transduction pathways: identification of DNase I-hypersensitive sites. Molecular Pharmacology. 44: 545-51. PMID 8396715  0.336
1992 Fischer-Colbrie R, Eskay RL, Eiden LE, Maas D. Transsynaptic regulation of galanin, neurotensin, and substance P in the adrenal medulla: Combinatorial control by second-messenger signaling pathways Journal of Neurochemistry. 59: 780-783. PMID 1378491  0.302
1992 MacArthur L, Iacangelo AL, Hsu CM, Eiden LE. Enkephalin biosynthesis is coupled to secretory activity via transcription of the proenkephalin A gene. Journal of Physiology, Paris. 86: 89-98. PMID 1364196 DOI: 10.1016/S0928-4257(05)80012-9  0.373
1983 Sherwood N, Eiden L, Brownstein M, Spiess J, Rivier J, Vale W. Characterization of a teleost gonadotropin-releasing hormone. Proceedings of the National Academy of Sciences of the United States of America. 80: 2794-8. PMID 6341999 DOI: 10.1073/Pnas.80.9.2794  0.562
1978 Borchardt RT, Olsen J, Eiden L, Schowen RL, Rutledge CO. The isolation and characterization of the methyl acceptor protein from adrenal chromaffin granules. Biochemical and Biophysical Research Communications. 83: 970-6. PMID 708445 DOI: 10.1016/0006-291X(78)91490-0  0.559
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