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Lin Lin - Publications

Affiliations: 
BIDMC 
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Yang M, Zirena IH, Kennedy QP, Patel A, Merrill-Skoloff G, Sack KD, Fulcidor E, Scartelli C, Guo S, Bekendam RH, Owegie OC, Xie H, Ghiran IC, Levy O, Lin L, et al. Galloylated polyphenols represent a new class of antithrombotic agents with broad activity against thiol isomerases. Journal of Thrombosis and Haemostasis : Jth. PMID 39952360 DOI: 10.1016/j.jtha.2025.01.021  0.748
2024 Yang M, Lin L, Flaumenhaft R. Protocol to identify flavonoid antagonists of the SARS-CoV-2 main protease. Star Protocols. 5: 102990. PMID 38583157 DOI: 10.1016/j.xpro.2024.102990  0.632
2023 Lin L, Chen DY, Scartelli C, Xie H, Merrill-Skoloff G, Yang M, Sun L, Saeed M, Flaumenhaft R. Plant flavonoid inhibition of SARS-CoV-2 main protease and viral replication. Iscience. 26: 107602. PMID 37664626 DOI: 10.1016/j.isci.2023.107602  0.663
2020 Greve E, Lindeman SV, Scartelli C, Lin L, Flaumenhaft R, Dockendorff C. Route exploration and synthesis of the reported pyridone-based PDI inhibitor STK076545. Organic & Biomolecular Chemistry. PMID 32812971 DOI: 10.1039/D0Ob01205J  0.668
2020 Schulman S, El-Darzi E, Florido MH, Friesen M, Merrill-Skoloff G, Brake MA, Schuster CR, Lin L, Westrick RJ, Cowan CA, Flaumenhaft R, BioResource N, Ouwehand WH, Peerlinck K, Freson K, et al. A coagulation defect arising from heterozygous premature termination of tissue factor. The Journal of Clinical Investigation. PMID 32663190 DOI: 10.1172/Jci133780  0.743
2020 Jiang Y, Lin L, Chen S, Jiang L, Kriegbaum MC, Gårdsvoll H, Hansen LV, Li J, Ploug M, Yuan C, Huang M. Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/α-neurotoxin Domain. International Journal of Biological Sciences. 16: 981-993. PMID 32140067 DOI: 10.7150/ijbs.39919  0.66
2020 Kalucka J, de Rooij LPMH, Goveia J, Rohlenova K, Dumas SJ, Meta E, Conchinha NV, Taverna F, Teuwen LA, Veys K, García-Caballero M, Khan S, Geldhof V, Sokol L, Chen R, ... ... Lin L, et al. Single-Cell Transcriptome Atlas of Murine Endothelial Cells. Cell. PMID 32059779 DOI: 10.1016/j.cell.2020.01.015  0.32
2019 Liu M, Lin L, Hansen GH, Ploug M, Hanlin L, Jiang L, Yuan C, Li J, Huang M. Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit. Febs Letters. PMID 31044429 DOI: 10.1002/1873-3468.13397  0.671
2018 Wang X, Xue G, Song M, Xu P, Chen D, Yuan C, Lin L, Flaumenhaft R, Li J, Huang M. Molecular basis of rutin inhibition of protein disulfide isomerase (PDI) by combined and experimental methods. Rsc Advances. 8: 18480-18491. PMID 35541126 DOI: 10.1039/c8ra02683a  0.733
2017 Chen S, Lin L, Yuan C, Gårdsvoll H, Kriegbaum MC, Ploug M, Huang M. Expression and crystallographic studies of the D1D2 domains of C4.4A, a homologous protein to the urokinase receptor. Acta Crystallographica. Section F, Structural Biology Communications. 73: 486-490. PMID 28777093 DOI: 10.1107/S2053230X17009748  0.379
2016 Bekendam RH, Bendapudi PK, Lin L, Nag PP, Pu J, Kennedy DR, Feldenzer A, Chiu J, Cook KM, Furie B, Huang M, Hogg PJ, Flaumenhaft R. A substrate-driven allosteric switch that enhances PDI catalytic activity. Nature Communications. 7: 12579. PMID 27573496 DOI: 10.1038/Ncomms12579  0.76
2016 Jiang L, Lin L, Li R, Yuan C, Xu M, Huang JH, Huang M. Dimer conformation of soluble PECAM-1, an endothelial marker. The International Journal of Biochemistry & Cell Biology. PMID 27270333 DOI: 10.1016/j.biocel.2016.06.001  0.685
2016 Gong L, Proulle V, Fang C, Hong Z, Lin Z, Liu M, Xue G, Yuan C, Lin L, Furie B, Flaumenhaft R, Andreasen P, Furie B, Huang M. A specific plasminogen activator inhibitor-1 antagonist derived from inactivated urokinase. Journal of Cellular and Molecular Medicine. PMID 27197780 DOI: 10.1111/Jcmm.12875  0.759
2015 Lin L, Gopal S, Sharda A, Passam F, Bowley SR, Stopa J, Xue G, Yuan C, Furie BC, Flaumenhaft R, Huang M, Furie B. Quercetin-3-rutinoside Inhibits Protein Disulfide Isomerase by Binding to Its b'x Domain. The Journal of Biological Chemistry. 290: 23543-52. PMID 26240139 DOI: 10.1074/Jbc.M115.666180  0.715
2015 Passam FH, Lin L, Gopal S, Stopa JD, Bellido-Martin L, Huang M, Furie BC, Furie B. Both platelet- and endothelial cell-derived ERp5 support thrombus formation in a laser-induced mouse model of thrombosis. Blood. 125: 2276-85. PMID 25624318 DOI: 10.1182/Blood-2013-12-547208  0.755
2014 Chen Z, Xu P, Chen J, Chen H, Hu P, Chen X, Lin L, Huang Y, Zheng K, Zhou S, Li R, Chen S, Liu J, Xue J, Huang M. Zinc phthalocyanine conjugated with the amino-terminal fragment of urokinase for tumor-targeting photodynamic therapy. Acta Biomaterialia. 10: 4257-68. PMID 24969665 DOI: 10.1016/j.actbio.2014.06.026  0.369
2012 Cho J, Kennedy DR, Lin L, Huang M, Merrill-Skoloff G, Furie BC, Furie B. Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrins. Blood. 120: 647-55. PMID 22653978 DOI: 10.1182/Blood-2011-08-372532  0.57
2012 Jasuja R, Passam FH, Kennedy DR, Kim SH, van Hessem L, Lin L, Bowley SR, Joshi SS, Dilks JR, Furie B, Furie BC, Flaumenhaft R. Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents. The Journal of Clinical Investigation. 122: 2104-13. PMID 22565308 DOI: 10.1172/Jci61228  0.764
2012 Xu X, Gårdsvoll H, Yuan C, Lin L, Ploug M, Huang M. Crystal structure of the urokinase receptor in a ligand-free form. Journal of Molecular Biology. 416: 629-41. PMID 22285761 DOI: 10.1016/j.jmb.2011.12.058  0.445
2011 Ngo JC, Jiang L, Lin Z, Yuan C, Chen Z, Zhang X, Yu H, Wang J, Lin L, Huang M. Structural basis for therapeutic intervention of uPA/uPAR system. Current Drug Targets. 12: 1729-43. PMID 21707478  0.669
2010 Bian C, Yuan C, Chen L, Meehan EJ, Jiang L, Huang Z, Lin L, Huang M. Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD. Proteins. 78: 1601-5. PMID 20146362 DOI: 10.1002/Prot.22676  0.634
2010 Lin L, Gårdsvoll H, Huai Q, Huang M, Ploug M. Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy. The Journal of Biological Chemistry. 285: 10982-92. PMID 20133942 DOI: 10.1074/jbc.M109.093492  0.424
2010 Liu Z, Lin L, Yuan C, Nicolaes GA, Chen L, Meehan EJ, Furie B, Furie B, Huang M. Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding. The Journal of Biological Chemistry. 285: 8824-9. PMID 20089867 DOI: 10.1074/Jbc.M109.080168  0.614
2010 Chen Z, Lin L, Huai Q, Huang M. Challenges for drug discovery - a case study of urokinase receptor inhibition. Combinatorial Chemistry & High Throughput Screening. 12: 961-7. PMID 20025562 DOI: 10.2174/138620709789824727  0.42
2008 Huai Q, Zhou A, Lin L, Mazar AP, Parry GC, Callahan J, Shaw DE, Furie B, Furie BC, Huang M. Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes. Nature Structural & Molecular Biology. 15: 422-3. PMID 18376415 DOI: 10.1038/Nsmb.1404  0.559
2007 Lin L, Huai Q, Huang M, Furie B, Furie BC. Crystal structure of the bovine lactadherin C2 domain, a membrane binding motif, shows similarity to the C2 domains of factor V and factor VIII. Journal of Molecular Biology. 371: 717-24. PMID 17583728 DOI: 10.1016/J.Jmb.2007.05.054  0.587
2005 Bian C, Yuan C, Lin L, Lin J, Shi X, Ye X, Huang Z, Huang M. Purification and preliminary crystallographic analysis of a Penicillium expansum lipase. Biochimica Et Biophysica Acta. 1752: 99-102. PMID 16112629 DOI: 10.1016/j.bbapap.2005.07.014  0.378
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