Leah E. Cowen, Ph.D.

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Microbiology Biology, Pathology
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"Leah Cowen"

Parents

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Linda Kohn grad student 2002 University of Toronto
 (Population genomics of drug resistance in the pathogenic yeast Candida albicans.)
James B. Anderson grad student 1997-2002 (Mycotree)
Susan L. Lindquist post-doc 2003-2007 (FlyTree)

Children

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Jessie MacAlpine grad student 2017- University of Toronto
Nicola T Case grad student 2018- University of Toronto
Emily H Xiong grad student 2020- University of Toronto
Sheena Singh-Babak grad student 2006-2011 University of Toronto (Mycotree)
Rebecca S. Shapiro grad student 2012 University of Toronto
Sheena D. Singh grad student 2012 University of Toronto
Nicole M. Robbins grad student 2013 University of Toronto
Jessica A. Hill grad student 2014 University of Toronto
Jing Lin Lucy Xie grad student 2010-2016 University of Toronto (Neurotree)
Teresa R. O'Meara post-doc (Microtree)
Sean D. Liston post-doc 2018-
Ci Fu post-doc 2020- University of Toronto (Microtree)
Dustin Duncan post-doc 2021- University of Toronto
BETA: Related publications

Publications

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Marquez L, Lee Y, Duncan D, et al. (2023) Potent Antifungal Activity of Penta--galloyl-β-d-Glucose against Drug-Resistant , , and Other Non- Species. Acs Infectious Diseases
Liu Z, Basso P, Hossain S, et al. (2023) Multifactor transcriptional control of alternative oxidase induction integrates diverse environmental inputs to enable fungal virulence. Nature Communications. 14: 4528
Robbins N, Cowen LE. (2023) Roles of Hsp90 in Candida albicans morphogenesis and virulence. Current Opinion in Microbiology. 75: 102351
Iyer KR, Li SC, Revie NM, et al. (2023) Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity. Cell Chemical Biology
Liu Z, MacAlpine J, Robbins N, et al. (2023) Construction of Candida albicans Strains with ATP-Analog-Sensitive Protein Kinase A and Hog1. Msphere. e0009523
Robbins N, Ketela T, Kim SH, et al. (2023) Chemical-Genetic Approaches for Exploring Mode of Action of Antifungal Compounds in the Fungal Pathogen Candida albicans. Methods in Molecular Biology (Clifton, N.J.). 2658: 145-165
Lee Y, Hossain S, MacAlpine J, et al. (2023) Functional genomic analysis of protein kinases reveals modulators of morphogenesis in diverse environments. Iscience. 26: 106145
Lash E, Prudent V, Stogios PJ, et al. (2023) Ent2 Governs Morphogenesis and Virulence in Part through Regulation of the Cdc42 Signaling Cascade in the Fungal Pathogen Candida albicans. Mbio. e0343422
Basso P, Dang EV, Urisman A, et al. (2022) Deep tissue infection by an invasive human fungal pathogen requires lipid-based suppression of the IL-17 response. Cell Host & Microbe. 30: 1589-1601.e5
Puumala E, Zaslaver O, Chen A, et al. (2022) The Trisubstituted Isoxazole MMV688766 Exerts Broad-Spectrum Activity against Drug-Resistant Fungal Pathogens through Inhibition of Lipid Homeostasis. Mbio. e0273022
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