Lorna Farrelly - Publications

Affiliations: 
2015- Pharmacology & Systems Therapeutics Icahn School of Medicine at Mount Sinai, New York, NY, United States 

13/47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Geiger LT, Balouek JA, Farrelly LA, Chen AS, Tang M, Bennett SN, Nestler EJ, Garcia BA, Maze I, Peña CJ. Early-life stress alters chromatin modifications in VTA to prime stress sensitivity. Biorxiv : the Preprint Server For Biology. PMID 38559030 DOI: 10.1101/2024.03.14.584631  0.734
2023 Al-Kachak A, Fulton SL, Farrelly LA, Lepack AE, Bastle RM, Kong L, Cathomas F, Newman EL, Menard C, Ramakrishnan A, Chan JC, Safovich P, Lyu Y, Covington HE, Shen L, et al. Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-induced gene expression and behavior. Biorxiv : the Preprint Server For Biology. PMID 37205414 DOI: 10.1101/2023.05.04.539464  0.683
2022 Fulton SL, Wenderski W, Lepack AE, Eagle AL, Fanutza T, Bastle RM, Ramakrishnan A, Hays EC, Neal A, Bendl J, Farrelly LA, Al-Kachak A, Lyu Y, Cetin B, Chan JC, et al. Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome. Nature Communications. 13: 6384. PMID 36289231 DOI: 10.1038/s41467-022-34200-0  0.661
2022 Farrelly LA, Zheng S, Schrode N, Topol A, Bhanu NV, Bastle RM, Ramakrishnan A, Chan JC, Cetin B, Flaherty E, Shen L, Gleason K, Tamminga CA, Garcia BA, Li H, et al. Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia. Nature Communications. 13: 2195. PMID 35459277 DOI: 10.1038/s41467-022-29922-0  0.699
2021 Zhao S, Chuh KN, Zhang B, Dul BE, Thompson RE, Farrelly LA, Liu X, Xu N, Xue Y, Roeder RG, Maze I, Muir TW, Li H. Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33526675 DOI: 10.1073/pnas.2016742118  0.707
2020 Lepack AE, Werner CT, Stewart AF, Fulton SL, Zhong P, Farrelly LA, Smith ACW, Ramakrishnan A, Lyu Y, Bastle RM, Martin JA, Mitra S, O'Connor RM, Wang ZJ, Molina H, et al. Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science (New York, N.Y.). 368: 197-201. PMID 32273471 DOI: 10.1126/Science.Aaw8806  0.736
2020 Farrelly L, Zhang S, Flaherty E, Topol A, Schrode N, Bastle R, Bhanu N, Garcia B, Li H, Brennand K, Maze I. T9. EPIGENETIC PROFILING IN SCHIZOPHRENIA DERIVED HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) AND NEURONS Schizophrenia Bulletin. 46: S234-S234. DOI: 10.1093/Schbul/Sbaa029.569  0.732
2019 Farrelly LA, Maze I. An emerging perspective on 'histone code' mediated regulation of neural plasticity and disease. Current Opinion in Neurobiology. 59: 157-163. PMID 31382083 DOI: 10.1016/J.Conb.2019.07.001  0.713
2019 Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. PMID 30867594 DOI: 10.1038/S41586-019-1024-7  0.787
2016 Lepack AE, Bagot RC, Peña CJ, Loh YE, Farrelly LA, Lu Y, Powell SK, Lorsch ZS, Issler O, Cates HM, Tamminga CA, Molina H, Shen L, Nestler EJ, Allis CD, et al. Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791098 DOI: 10.1073/Pnas.1608270113  0.772
2016 Farrelly LA, Dill BD, Molina H, Birtwistle MR, Maze I. Current Proteomic Methods to Investigate the Dynamics of Histone Turnover in the Central Nervous System. Methods in Enzymology. 574: 331-54. PMID 27423867 DOI: 10.1016/Bs.Mie.2016.01.013  0.724
2016 Farrelly LA, Dill BD, Molina H, Birtwistle MR, Maze I. Current Proteomic Methods to Investigate the Dynamics of Histone Turnover in the Central Nervous System Methods in Enzymology. DOI: 10.1016/bs.mie.2016.01.013  0.646
2015 Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, et al. Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron. 87: 77-94. PMID 26139371 DOI: 10.1016/J.Neuron.2015.06.014  0.785
Low-probability matches (unlikely to be authored by this person)
2015 Farrelly L, Föcking M, Piontkewitz Y, Dicker P, English J, Wynne K, Cannon M, Cagney G, Cotter DR. Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence. Developmental Neuroscience. 37: 43-55. PMID 25592202 DOI: 10.1159/000368305  0.283
2017 Farrelly L, Rosato-Siri MV, Föcking M, Codagnone M, Reines A, Dicker P, Wynne K, Farrell M, Cannon M, Cagney G, Pasquini JM, Cotter DR. The Effects of Prenatal Iron Deficiency and Risperidone Treatment on the Rat Frontal Cortex:  A Proteomic Analysis. Proteomics. PMID 28762254 DOI: 10.1002/Pmic.201600407  0.277
1983 Weinberg ES, Hendricks MB, Hemminki K, Kuwabara PE, Farrelly LA. Timing and rates of synthesis of early histone mRNA in the embryo of Strongylocentrotus purpuratus. Developmental Biology. 98: 117-29. PMID 6862100 DOI: 10.1016/0012-1606(83)90340-8  0.248
2014 Farrelly L, Föcking M, Piontkewitz Y, Dicker P, English J, Wynne K, Cannon M, Weiner I, Cagney G, Cotter D. Poster #T75 PRENATAL EXPOSURE TO MATERNAL IMMUNE STIMULATION LEADS TO CHANGES IN MYELIN PROTEINS IN THE ADULT RAT PREFRONTAL CORTEX WHICH CAN BE PREVENTED BY RISPERIDONE IN ADOLESENCE Schizophrenia Research. 153: S315. DOI: 10.1016/S0920-9964(14)70892-8  0.234
2014 Farrelly LA, Föcking M, Cotter DR. Insights from proteomic studies on schizophrenia preclinical models: What can we learn for drug discovery? Proteomics and Metabolomics in Psychiatry. 29: 56-73. DOI: 10.1159/000358028  0.136
2013 Farrelly LA, Savage NT, O'Callaghan C, Toulouse A, Yilmazer-Hanke DM. Therapeutic concentrations of valproate but not amitriptyline increase neuropeptide Y (NPY) expression in the human SH-SY5Y neuroblastoma cell line. Regulatory Peptides. 186: 123-30. PMID 23994577 DOI: 10.1016/j.regpep.2013.08.005  0.128
2014 Farrelly LA, Dicker P, Wynne K, English J, Cagney G, Föcking M, Cotter DR. Adolescent Risperidone treatment alters protein expression associated with protein trafficking and cellular metabolism in the adult rat prefrontal cortex. Proteomics. 14: 1574-8. PMID 24733778 DOI: 10.1002/pmic.201300466  0.113
2007 Oates JC, Farrelly LW, Hofbauer AF, Wang W, Gilkeson GS. Association of reactive oxygen and nitrogen intermediate and complement levels with apoptosis of peripheral blood mononuclear cells in lupus patients Arthritis and Rheumatism. 56: 3738-3747. PMID 17968874 DOI: 10.1002/Art.22955  0.109
2009 Farrelly L. Early in 2009, cult studio the designers republic shocked its fans by going into voluntary liquidation. Its founder talk us through 23 years of 'brain-aided design' Eye - International Review of Graphic Design. 10-21.  0.095
2002 Reilly CM, Farrelly LW, Viti D, Redmond ST, Hutchison F, Ruiz P, Manning P, Connor J, Gilkeson GS. Modulation of renal disease in MRL/lpr mice by pharmacologic inhibition of inducible nitric oxide synthase. Kidney International. 61: 839-46. PMID 11849435 DOI: 10.1046/j.1523-1755.2002.00230.x  0.09
2007 Farrelly L. New for old Crafts. 26-32.  0.066
2009 Farrelly L. Fired up and hired Eye - International Review of Graphic Design. 56-59.  0.057
2012 Farrelly LA, Föcking M, English J, Cagney G, Cotter D. Poster #135 MYELIN PATHOLOGYAND ITS RELATIONSHIP TO IRON HOMEOSTASISIN SCHIZOPHRENIA Schizophrenia Research. 136: S140. DOI: 10.1016/S0920-9964(12)70449-8  0.054
2014 Farrelly L. New visions: Re-imagine ageing RIBA design competition 2013 Architectural Design. 84: 112-121. DOI: 10.1002/ad.1737  0.049
2007 Farrelly L. Linked by a thread Crafts. 46-49.  0.041
2011 Farrelly L. Fantastic Nora Fok Crafts. 28-33.  0.041
2003 Gibb DM, Duong T, Tookey PA, Sharland M, Tudor-Williams G, Novelli V, Butler K, Riordan A, Farrelly L, Masters J, Peckham CS, Dunn DT. Decline in mortality, AIDS, and hospital admissions in perinatally HIV-1 infected children in the United Kingdom and Ireland British Medical Journal. 327: 1019-1023. PMID 14593035  0.038
2015 Oza AM, Cook AD, Pfisterer J, Embleton A, Ledermann JA, Pujade-Lauraine E, Kristensen G, Carey MS, Beale P, Cervantes A, Park-Simon TW, Rustin G, Joly F, Mirza MR, Plante M, ... ... Farrelly L, et al. Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 randomised trial. The Lancet. Oncology. 16: 928-36. PMID 26115797 DOI: 10.1016/S1470-2045(15)00086-8  0.037
2014 Farrelly L. Redefining, reinventing and realigning design for demographic change Architectural Design. 84: 8-13. DOI: 10.1002/ad.1722  0.033
2013 Vergote I, Elser G, Votan B, Farrelly L, De Roover J, Bryce J, Du Bois A. Roadmap for the european network of gynaecological trial groups (ENGOT) trials International Journal of Gynecological Cancer. 23: 1339-1343. PMID 23970159 DOI: 10.1097/IGC.0b013e31829b87da  0.026
2016 Ledermann JA, Embleton AC, Raja F, Perren TJ, Jayson GC, Rustin GJ, Kaye SB, Hirte H, Eisenhauer E, Vaughan M, Friedlander M, González-Martín A, Stark D, Clark E, Farrelly L, et al. Cediranib in patients with relapsed platinum-sensitive ovarian cancer (ICON6): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet (London, England). 387: 1066-74. PMID 27025186 DOI: 10.1016/S0140-6736(15)01167-8  0.026
2006 LePrevost M, Green H, Flynn J, Head S, Clapson M, Lyall H, Novelli V, Farrelly L, Walker AS, Burger DM, Gibb DM. Adherence and acceptability of once daily Lamivudine and abacavir in human immunodeficiency virus type-1 infected children. The Pediatric Infectious Disease Journal. 25: 533-7. PMID 16732152 DOI: 10.1097/01.inf.0000222415.40563.d4  0.026
2004 Chintu C, Bhat GJ, Walker AS, Mulenga V, Sinyinza F, Lishimpi K, Farrelly L, Kaganson N, Zumla A, Gillespie SH, Nunn AJ, Gibb DM. Co-trimoxazole as prophylaxis against opportunistic infections in HIV-infected Zambian children (CHAP): A double-blind randomised placebo-controlled trial Lancet. 364: 1865-1871. PMID 15555666 DOI: 10.1016/S0140-6736(04)17442-4  0.025
2005 Bergshoeff A, Burger D, Verweij C, Farrelly L, Flynn J, Le Prevost M, Walker S, Novelli V, Lyall H, Khoo S, Gibb D. Plasma pharmacokinetics of once- versus twice-daily lamivudine and abacavir: Simplification of combination treatment in HIV-1-infected children (PENTA-13) Antiviral Therapy. 10: 239-246. PMID 15865218  0.024
2010 Farrelly L. Make each letter speak out loud Eye - International Review of Graphic Design. 52-62.  0.021
2014 Farrelly L. Housing from 8 to 80: An AD ideas project Architectural Design. 84: 126-135. DOI: 10.1002/ad.1739  0.021
2013 Soane J, Farrelly L, Binet H. Family home and Soane Crafts. 40-43.  0.015
2004 Mhlongo SWP, Maduna PMH, Prime KP, Jungmann EA, Edwards SG, Gibb DM, Duong T, Tookey PA, Sharland M, Tudor-Williams G, Novelli V, Butler K, Riordan A, Farrelly L, Masters J, et al. Decline in mortality in children with HIV in the UK and Ireland [5] (multiple letters) British Medical Journal. 328: 523-524. PMID 14988207  0.012
2012 Farrelly L. Flights of fancy Eye - International Review of Graphic Design. 48-53.  0.01
2012 de Oliveira FL, Farrelly L. The regeneration of a naval city: Portsmouth Parallel Patterns of Shrinking Cities and Urban Growth: Spatial Planning For Sustainable Development of City Regions and Rural Areas. 245-255.  0.01
2010 Jacqz-Aigrain E, Harrison L, Zhao W, Compagnucci A, Castro H, Farrelly L, Saidi Y, Hamadache D, Welch S, Wintergerst U, Forcat S, Hadjou G, Firtion G, Snowden W, Giaquinto C, et al. Pharmacokinetic study of once-daily versus twice-daily abacavir and lamivudine in HIV type-1-infected children aged 3-<36 months Antiviral Therapy. 15: 297-305. PMID 20516550 DOI: 10.3851/IMP1532  0.01
2009 Farrelly L. Sampling the modern Eye - International Review of Graphic Design. 24-27.  0.01
2009 Farrelly L. Six degrees of Erik Spiekermann Eye - International Review of Graphic Design. 42-47.  0.01
2001 Farrelly L. One person's opinion: Field-erect boilers Engineered Systems. 18: 50.  0.01
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