Ambuj Kumar, Ph.D - Publications

Affiliations: 
Bioinformatics and Computational Biology Iowa State University, Ames, IA, United States 
Area:
Structural Bioinformatics, Molecular Evolution, Zika Virus
Website:
http://rochelab.org/ambuj/

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Kumar A, Purohit R. Use of long term molecular dynamics simulation in predicting cancer associated SNPs. Plos Computational Biology. 10: e1003318. PMID 24722014 DOI: 10.1371/Journal.Pcbi.1003318  0.394
2014 Kumar A, Rajendran V, Sethumadhavan R, Shukla P, Tiwari S, Purohit R. Computational SNP analysis: current approaches and future prospects. Cell Biochemistry and Biophysics. 68: 233-9. PMID 23852834 DOI: 10.1007/S12013-013-9705-6  0.376
2014 Kumar A, Rajendran V, Sethumadhavan R, Purohit R. Relationship between a point mutation S97C in CK1δ protein and its affect on ATP-binding affinity. Journal of Biomolecular Structure & Dynamics. 32: 394-405. PMID 23527964 DOI: 10.1080/07391102.2013.770373  0.4
2014 Kumar A, Braun E, Kimball R. Adaptive evolution of Cep63-CEP152 centrosome microcephaly ring in association with brain size shift in mammals F1000research. 5. DOI: 10.7490/F1000Research.1096500.1  0.502
2013 Kumar A, Rajendran V, Sethumadhavan R, Purohit R. Identifying novel oncogenes: a machine learning approach. Interdisciplinary Sciences, Computational Life Sciences. 5: 241-6. PMID 24402816 DOI: 10.1007/S12539-013-0151-3  0.377
2013 Kumar A, Rajendran V, Sethumadhavan R, Purohit R. Molecular dynamic simulation reveals damaging impact of RAC1 F28L mutation in the switch I region. Plos One. 8: e77453. PMID 24146998 DOI: 10.1371/Journal.Pone.0077453  0.392
2013 Kumar A, Purohit R. Cancer associated E17K mutation causes rapid conformational drift in AKT1 pleckstrin homology (PH) domain. Plos One. 8: e64364. PMID 23741320 DOI: 10.1371/Journal.Pone.0064364  0.4
2013 Kumar A, Kamaraj B, Sethumadhavan R, Purohit R. Evolution driven structural changes in CENP-E motor domain. Interdisciplinary Sciences, Computational Life Sciences. 5: 102-11. PMID 23740391 DOI: 10.1007/S12539-013-0137-1  0.359
2013 Kumar A, Rajendran V, Sethumadhavan R, Purohit R. Evidence of colorectal cancer-associated mutation in MCAK: a computational report. Cell Biochemistry and Biophysics. 67: 837-51. PMID 23564489 DOI: 10.1007/S12013-013-9572-1  0.438
2013 Kumar A, Rajendran V, Sethumadhavan R, Purohit R. CEP proteins: the knights of centrosome dynasty. Protoplasma. 250: 965-83. PMID 23456457 DOI: 10.1007/S00709-013-0488-9  0.349
2013 Kumar A, Rajendran V, Sethumadhavan R, Purohit R. Computational investigation of cancer-associated molecular mechanism in Aurora A (S155R) mutation. Cell Biochemistry and Biophysics. 66: 787-96. PMID 23412841 DOI: 10.1007/S12013-013-9524-9  0.417
2013 Kumar A, Rajendran V, Sethumadhavan R, Purohit R. Roadmap to determine the point mutations involved in cardiomyopathy disorder: a Bayesian approach. Gene. 519: 34-40. PMID 23403236 DOI: 10.1016/J.Gene.2013.01.056  0.385
2013 Kumar A, Rajendran V, sethumadhavan R, Purohit R. Insight into Nek2A activity regulation and its pharmacological prospects Egyptian Journal of Medical Human Genetics. 14: 213-219. DOI: 10.1016/J.Ejmhg.2012.10.006  0.338
2012 Kumar A, Rajendran V, Sethumadhavan R, Purohit R. In silico prediction of a disease-associated STIL mutant and its affect on the recruitment of centromere protein J (CENPJ). Febs Open Bio. 2: 285-93. PMID 23772360 DOI: 10.1016/J.Fob.2012.09.003  0.415
2012 Gulati G, Gaonkar KS, Kamraj B, Kumar A, Purohit R. Structure based energy calculation to determine the regulation of G protein signalling by RGS and RGS-G protein interaction specificity. Interdisciplinary Sciences, Computational Life Sciences. 4: 173-82. PMID 23292690 DOI: 10.1007/S12539-012-0130-0  0.345
2012 Kumar A, Purohit R. Computational centrosomics: an approach to understand the dynamic behaviour of centrosome. Gene. 511: 125-6. PMID 23000070 DOI: 10.1016/J.Gene.2012.09.040  0.352
2012 Kumar A, Purohit R. Computational screening and molecular dynamics simulation of disease associated nsSNPs in CENP-E. Mutation Research. 738: 28-37. PMID 22974711 DOI: 10.1016/J.Mrfmmm.2012.08.005  0.381
2012 Kumar A, Purohit R. Computational investigation of pathogenic nsSNPs in CEP63 protein. Gene. 503: 75-82. PMID 22555018 DOI: 10.1016/J.Gene.2012.04.032  0.388
2011 Kumar A, Mishra M, Bhardwaj D, Agarwal K. In silico analysis and prevention of coxsackie virus b4 induced insulin dependent diabetes mellitus F1000research. 2. DOI: 10.7490/F1000Research.2062.1  0.308
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