Joshua J Gruber - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Computational biology

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Li Y, Tan M, Akkari-Henić A, Zhang L, Kip M, Sun S, Sepers JJ, Xu N, Ariyurek Y, Kloet SL, Davis RP, Mikkers H, Gruber JJ, Snyder MP, Li X, et al. Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs. Nature Biomedical Engineering. PMID 38778183 DOI: 10.1038/s41551-024-01204-8  0.735
2024 Nshanian M, Geller BS, Gruber JJ, Chleilat F, Camarillo JM, Kelleher NL, Zhao Y, Snyder MP. Short-chain fatty acids propionate and butyrate control growth and differentiation linked to cellular metabolism. Research Square. PMID 38410440 DOI: 10.21203/rs.3.rs-3935562/v1  0.451
2024 Rajkumar S, Dixon D, Lipchik AM, Gruber JJ. An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation. Journal of Visualized Experiments : Jove. PMID 38345235 DOI: 10.3791/66054  0.741
2024 Nshanian M, Geller BS, Gruber JJ, Chleilat F, Camarillo JM, Kelleher NL, Zhao Y, Snyder MP. Short-chain fatty acids propionate and butyrate control growth and differentiation linked to cellular metabolism. Biorxiv : the Preprint Server For Biology. PMID 38293216 DOI: 10.1101/2024.01.11.575111  0.451
2023 Li AM, He B, Karagiannis D, Li Y, Jiang H, Srinivasan P, Ramirez Y, Zhou MN, Curtis C, Gruber JJ, Lu C, Rankin EB, Ye J. Serine starvation silences estrogen receptor signaling through histone hypoacetylation. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302489120. PMID 37695911 DOI: 10.1073/pnas.2302489120  0.331
2023 Gaddameedi JD, Chou T, Geller BS, Rangarajan A, Swaminathan TA, Dixon D, Long K, Golder CJ, Vuong VA, Banuelos S, Greenhouse R, Snyder MP, Lipchik AM, Gruber JJ. Acetyl-Click Screening Platform Identifies Small-Molecule Inhibitors of Histone Acetyltransferase 1 (HAT1). Journal of Medicinal Chemistry. PMID 37027002 DOI: 10.1021/acs.jmedchem.3c00039  0.757
2021 Sanghi A, Gruber JJ, Metwally A, Jiang L, Reynolds W, Sunwoo J, Orloff L, Chang HY, Kasowski M, Snyder MP. Chromatin accessibility associates with protein-RNA correlation in human cancer. Nature Communications. 12: 5732. PMID 34593797 DOI: 10.1038/s41467-021-25872-1  0.756
2020 Li Y, Gruber JJ, Litzenburger UM, Zhou Y, Miao YR, LaGory EL, Li AM, Hu Z, Yip M, Hart LS, Maris JM, Chang HY, Giaccia AJ, Ye J. Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia. Cell Death & Disease. 11: 102. PMID 32029721 DOI: 10.1038/S41419-020-2303-9  0.439
2019 Telli ML, Chu C, Badve SS, Vinayak S, Silver DP, Isakoff SJ, Kaklamani V, Gradishar W, Stearns V, Connolly RM, Ford JM, Gruber JJ, Adams S, Garber J, Tung N, et al. Association of Tumor Infiltrating Lymphocytes with Homologous Recombination Deficiency and BRCA1/2 Status in Patients with Early Triple-Negative Breast Cancer: A Pooled Analysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31796517 DOI: 10.1158/1078-0432.Ccr-19-0664  0.381
2019 Gruber JJ, Chen J, Geller B, Jäger N, Lipchik AM, Wang G, Kurian AW, Ford JM, Snyder MP. Chromatin Remodeling in Response to BRCA2-Crisis. Cell Reports. 28: 2182-2193.e6. PMID 31433991 DOI: 10.1016/J.Celrep.2019.07.057  0.729
2019 Stowers RS, Shcherbina A, Israeli J, Gruber JJ, Chang J, Nam S, Rabiee A, Teruel MN, Snyder MP, Kundaje A, Chaudhuri O. Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility. Nature Biomedical Engineering. PMID 31285581 DOI: 10.1038/S41551-019-0420-5  0.513
2019 Gruber JJ, Geller B, Lipchik AM, Chen J, Salahudeen AA, Ram AN, Ford JM, Kuo CJ, Snyder MP. HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding. Molecular Cell. PMID 31278053 DOI: 10.1016/J.Molcel.2019.05.034  0.739
2019 Chen J, Haanpää MK, Gruber JJ, Jäger N, Ford JM, Snyder MP. High-Resolution Bisulfite-Sequencing of Peripheral Blood DNA Methylation in Early-Onset and Familial Risk Breast Cancer Patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31175093 DOI: 10.1158/1078-0432.Ccr-18-2423  0.746
2019 Gruber JJ, Afghahi A, Hatton A, Scott D, McMillan A, Ford JM, Telli ML. Talazoparib beyond BRCA: A phase II trial of talazoparib monotherapy in BRCA1 and BRCA2 wild-type patients with advanced HER2-negative breast cancer or other solid tumors with a mutation in homologous recombination (HR) pathway genes. Journal of Clinical Oncology. 37: 3006-3006. DOI: 10.1200/Jco.2019.37.15_Suppl.3006  0.395
2019 Telli M, Vinayak S, Khododoust, Gruber J, Ford J, Sanchez P, Banayan N, Azimi S, Tumeh P, Newman A, Alizadeh A. Abstract PD5-12: Spatial mapping of the immune microenvironment in primary triple-negative breast cancer (TNBC) and association with neoadjuvant therapy response Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Pd5-12  0.364
2019 Gruber J, Chen J, Geller B, Jager N, Lipchik A, Snyder M. Abstract P3-05-02: Not presented Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P3-05-02  0.658
2018 Liu Q, Van Bortle K, Zhang Y, Zhao MT, Zhang JZ, Geller BS, Gruber JJ, Jiang C, Wu JC, Snyder MP. Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid. Scientific Reports. 8: 12960. PMID 30154523 DOI: 10.1038/S41598-018-31192-0  0.576
2018 Gruber JJ, Juntilla MM, Yang S, Geller B, Jager N, Lin C, Lipchik AM, Chen J, Ram A, Vinayak S, Telli ML, West RB, Ford JM, Snyder MP. Abstract 4749: VISTA immune checkpoint deregulation in human triple-negative breast cancer Cancer Research. 78: 4749-4749. DOI: 10.1158/1538-7445.Am2018-4749  0.749
2017 Gruber JJ, Telli ML. Outstanding Questions in the Clinical Management of Triple-Negative Breast Cancer. Journal of Oncology Practice. 13: 305-307. PMID 28489983 DOI: 10.1200/Jop.2017.023341  0.331
2017 Reza Sailani M, Jahanbani F, Nasiri J, Behnam M, Salehi M, Sedghi M, Hoseinzadeh M, Takahashi S, Zia A, Gruber J, Lynch JL, Lam D, Winkelmann J, Amirkiai S, Pang B, et al. Association of AHSG with alopecia and mental retardation (APMR) syndrome. Human Genetics. PMID 28054173 DOI: 10.1007/S00439-016-1756-5  0.716
2017 Gruber J, Snyder M. Abstract P6-05-01: Low BRCA2 levels cause epigenetic activation of growth adaptive pathways without inducing recurrent genomic mutations Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P6-05-01  0.577
2015 Gruber JJ, Colevas AD. Differentiated thyroid cancer: focus on emerging treatments for radioactive iodine-refractory patients. The Oncologist. 20: 113-26. PMID 25616432 DOI: 10.1634/Theoncologist.2014-0313  0.317
2013 Olejniczak SH, La Rocca G, Gruber JJ, Thompson CB. Long-lived microRNA-Argonaute complexes in quiescent cells can be activated to regulate mitogenic responses. Proceedings of the National Academy of Sciences of the United States of America. 110: 157-62. PMID 23248281 DOI: 10.1073/Pnas.1219958110  0.508
2012 Gruber JJ, Olejniczak SH, Yong J, La Rocca G, Dreyfuss G, Thompson CB. Ars2 promotes proper replication-dependent histone mRNA 3' end formation. Molecular Cell. 45: 87-98. PMID 22244333 DOI: 10.1016/J.Molcel.2011.12.020  0.525
2011 Wise DR, Ward PS, Shay JE, Cross JR, Gruber JJ, Sachdeva UM, Platt JM, DeMatteo RG, Simon MC, Thompson CB. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability. Proceedings of the National Academy of Sciences of the United States of America. 108: 19611-6. PMID 22106302 DOI: 10.1073/Pnas.1117773108  0.644
2011 Cash TP, Gruber JJ, Hartman TR, Henske EP, Simon MC. Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription. Oncogene. 30: 2534-46. PMID 21258407 DOI: 10.1038/onc.2010.628  0.33
2010 Zhao F, Mancuso A, Bui TV, Tong X, Gruber JJ, Swider CR, Sanchez PV, Lum JJ, Sayed N, Melo JV, Perl AE, Carroll M, Tuttle SW, Thompson CB. Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming. Oncogene. 29: 2962-72. PMID 20228846 DOI: 10.1038/Onc.2010.67  0.474
2009 Tong X, Zhao F, Mancuso A, Gruber JJ, Thompson CB. The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 106: 21660-5. PMID 19995986 DOI: 10.1073/Pnas.0911316106  0.491
2009 Sabin LR, Zhou R, Gruber JJ, Lukinova N, Bambina S, Berman A, Lau CK, Thompson CB, Cherry S. Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila. Cell. 138: 340-51. PMID 19632183 DOI: 10.1016/J.Cell.2009.04.045  0.459
2009 Gruber JJ, Zatechka DS, Sabin LR, Yong J, Lum JJ, Kong M, Zong WX, Zhang Z, Lau CK, Rawlings J, Cherry S, Ihle JN, Dreyfuss G, Thompson CB. Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell. 138: 328-39. PMID 19632182 DOI: 10.1016/J.Cell.2009.04.046  0.637
2007 Kong M, Bui TV, Ditsworth D, Gruber JJ, Goncharov D, Krymskaya VP, Lindsten T, Thompson CB. The PP2A-associated protein alpha4 plays a critical role in the regulation of cell spreading and migration. The Journal of Biological Chemistry. 282: 29712-20. PMID 17693407 DOI: 10.1074/Jbc.M703159200  0.36
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