Deborah L. Gumucio - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
globin gene switching, familial mediterranean fever, intestinal development

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Walton KD, Gumucio DL. Hedgehog Signaling in Intestinal Development and Homeostasis. Annual Review of Physiology. PMID 33035430 DOI: 10.1146/annurev-physiol-031620-094324  0.305
2019 Zheng Y, Xue X, Shao Y, Wang S, Esfahani SN, Li Z, Muncie JM, Lakins JN, Weaver VM, Gumucio DL, Fu J. Controlled modelling of human epiblast and amnion development using stem cells. Nature. PMID 31511693 DOI: 10.1038/S41586-019-1535-2  0.341
2019 Nasr Esfahani S, Shao Y, Resto Irizarry AM, Li Z, Xue X, Gumucio DL, Fu J. Microengineered human amniotic ectoderm tissue array for high-content developmental phenotyping. Biomaterials. 216: 119244. PMID 31207406 DOI: 10.1016/J.Biomaterials.2019.119244  0.324
2019 Wang S, Walton KD, Gumucio DL. Signals and forces shaping organogenesis of the small intestine. Current Topics in Developmental Biology. 132: 31-65. PMID 30797512 DOI: 10.1016/Bs.Ctdb.2018.12.001  0.387
2018 Wang S, Cebrian C, Schnell S, Gumucio DL. Radial WNT5A-Guided Post-mitotic Filopodial Pathfinding Is Critical for Midgut Tube Elongation. Developmental Cell. 46: 173-188.e3. PMID 30016620 DOI: 10.1016/J.Devcel.2018.06.011  0.315
2018 Walton KD, Mishkind D, Riddle MR, Tabin CJ, Gumucio DL. Blueprint for an intestinal villus: Species-specific assembly required. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 29513926 DOI: 10.1002/Wdev.317  0.389
2018 Razumilava N, Gumucio DL, Samuelson LC, Shah YM, Nusrat A, Merchant JL. Indian Hedgehog Suppresses Intestinal Inflammation. Cellular and Molecular Gastroenterology and Hepatology. 5: 63-64. PMID 29276751 DOI: 10.1016/J.Jcmgh.2017.10.003  0.344
2017 Taniguchi K, Shao Y, Townshend RF, Cortez CL, Harris CE, Meshinchi S, Kalantry S, Fu J, O'Shea KS, Gumucio DL. An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells. The Journal of Cell Biology. PMID 29021220 DOI: 10.1083/Jcb.201704085  0.301
2017 Shao Y, Taniguchi K, Townshend RF, Miki T, Gumucio DL, Fu J. A pluripotent stem cell-based model for post-implantation human amniotic sac development. Nature Communications. 8: 208. PMID 28785084 DOI: 10.1038/S41467-017-00236-W  0.308
2017 Muza-Moons MM, Urquhart A, Chandhrasekhar D, Gumucio DL. Hedgehog Pathway Activation Protects the Colon during Inflammatory Colitis Gastroenterology. 152: S143. DOI: 10.1016/S0016-5085(17)30807-7  0.321
2016 Kumar N, Srivillibhuthur M, Joshi S, Walton KD, Zhou A, Faller WJ, Perekatt AO, Sansom OJ, Gumucio DL, Xing J, Bonder EM, Gao N, White E, Verzi MP. A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. Development (Cambridge, England). 143: 3711-3722. PMID 27802136 DOI: 10.1242/Dev.137992  0.362
2016 Freddo AM, Shoffner SK, Shao Y, Taniguchi K, Grosse AS, Guysinger MN, Wang S, Rudraraju S, Margolis B, Garikipati K, Schnell S, Gumucio DL. Coordination of signaling and tissue mechanics during morphogenesis of murine intestinal villi: a role for mitotic cell rounding. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 27476872 DOI: 10.1039/C6Ib00046K  0.362
2016 Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL. Transcriptome of the inner circular smooth muscle of the developing mouse intestine: evidence for regulation of visceral smooth muscle genes by the Hedgehog target gene, cJun. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 26930384 DOI: 10.1002/Dvdy.24399  0.333
2016 Gurdziel K, Vogt KR, Schneider G, Richards N, Gumucio DL. Computational prediction and experimental validation of novel Hedgehog-responsive enhancers linked to genes of the Hedgehog pathway. Bmc Developmental Biology. 16: 4. PMID 26912062 DOI: 10.1186/S12861-016-0106-0  0.372
2016 Syu LJ, Zhao X, Zhang Y, Grachtchouk M, Demitrack E, Ermilov A, Wilbert DM, Zheng X, Kaatz A, Greenson JK, Gumucio DL, Merchant JL, di Magliano MP, Samuelson LC, Dlugosz AA. Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways. Oncotarget. PMID 26859571 DOI: 10.18632/Oncotarget.7182  0.377
2015 Walton KD, Whidden M, Kolterud Å, Shoffner S, Czerwinski MJ, Kushwaha J, Parmar N, Chandhrasekhar D, Freddo AM, Schnell S, Gumucio DL. Villification in the mouse: Bmp signals control intestinal villus patterning. Development (Cambridge, England). PMID 26721501 DOI: 10.1242/Dev.130112  0.346
2015 Gurdziel K, Lorberbaum DS, Udager AM, Song JY, Richards N, Parker DS, Johnson LA, Allen BL, Barolo S, Gumucio DL. Identification and Validation of Novel Hedgehog-Responsive Enhancers Predicted by Computational Analysis of Ci/Gli Binding Site Density. Plos One. 10: e0145225. PMID 26710299 DOI: 10.1371/Journal.Pone.0145225  0.574
2015 Taniguchi K, Shao Y, Townshend RF, Tsai YH, DeLong CJ, Lopez SA, Gayen S, Freddo AM, Chue DJ, Thomas DJ, Spence JR, Margolis B, Kalantry S, Fu J, O'Shea KS, ... Gumucio DL, et al. Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells. Stem Cell Reports. PMID 26626176 DOI: 10.1016/J.Stemcr.2015.10.015  0.369
2015 Freddo AM, Grosse AS, Taniguchi K, Guysinger MN, Margolis B, Turner JR, Gumucio DL. 349 Villus Morphogenesis Re-Examined: Unique Cell Divisions Carve out Intestinal Villi Gastroenterology. 148: S-75. DOI: 10.1016/S0016-5085(15)30261-4  0.365
2014 Prakash A, Udager AM, Saenz DA, Gumucio DL. Roles for Nkx2-5 and Gata3 in the ontogeny of the murine smooth muscle gastric ligaments American Journal of Physiology - Gastrointestinal and Liver Physiology. 307: G430-G436. PMID 24970776 DOI: 10.1152/Ajpgi.00360.2013  0.595
2014 Whiteman EL, Fan S, Harder JL, Walton KD, Liu CJ, Soofi A, Fogg VC, Hershenson MB, Dressler GR, Deutsch GH, Gumucio DL, Margolis B. Crumbs3 is essential for proper epithelial development and viability. Molecular and Cellular Biology. 34: 43-56. PMID 24164893 DOI: 10.1128/Mcb.00999-13  0.365
2014 Udager AM, Prakash A, Saenz DA, Schinke M, Moriguchi T, Jay PY, Lim KC, Engel JD, Gumucio DL. Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. Gastroenterology. 146: 157-65.e10. PMID 24120474 DOI: 10.1053/J.Gastro.2013.10.008  0.606
2014 Udager AM, Prakash A, Saenz DA, Schinke M, Moriguchi T, Jay PY, Lim KC, Engel JD, Gumucio DL. Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3 Gastroenterology. 146: 157-165.e10. DOI: 10.1053/j.gastro.2013.10.008  0.519
2014 Freddo AM, Taniguchi K, Grosse AS, Margolis B, Turner JR, Gumucio DL. 250 Ezrin, an Apical Surface Protein, Functions in a Distinct Type of Cell Division in the Early Intestinal Epithelium to Aid Expansion of Luminal Surface Gastroenterology. 146: S-60. DOI: 10.1016/S0016-5085(14)60209-2  0.334
2013 Liu HX, Ermilov A, Grachtchouk M, Li L, Gumucio DL, Dlugosz AA, Mistretta CM. Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance. Developmental Biology. 382: 82-97. PMID 23916850 DOI: 10.1016/J.Ydbio.2013.07.022  0.404
2013 Sun Y, Zhang M, Chen CC, Gillilland M, Sun X, El-Zaatari M, Huffnagle GB, Young VB, Zhang J, Hong SC, Chang YM, Gumucio DL, Owyang C, Kao JY. Stress-induced corticotropin-releasing hormone-mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice. Gastroenterology. 144: 1478-87, 1487.e1-8. PMID 23470617 DOI: 10.1053/J.Gastro.2013.02.038  0.351
2013 Freddo AM, Taniguchi K, Grosse AS, Gumucio DL. 128 Evidence for Two Functionally Distinct Types of Cell Division in the Early Intestinal Epithelium Gastroenterology. 144: S-30-S-31. DOI: 10.1016/S0016-5085(13)60108-0  0.343
2012 Syu LJ, El-Zaatari M, Eaton KA, Liu Z, Tetarbe M, Keeley TM, Pero J, Ferris J, Wilbert D, Kaatz A, Zheng X, Qiao X, Grachtchouk M, Gumucio DL, Merchant JL, et al. Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia. The American Journal of Pathology. 181: 2114-25. PMID 23036899 DOI: 10.1016/J.Ajpath.2012.08.017  0.35
2012 VanDussen KL, Carulli AJ, Keeley TM, Patel SR, Puthoff BJ, Magness ST, Tran IT, Maillard I, Siebel C, Kolterud A, Grosse AS, Gumucio DL, Ernst SA, Tsai YH, Dempsey PJ, et al. Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells Development. 139: 488-497. PMID 22190634 DOI: 10.1242/Dev.070763  0.419
2012 Liu HX, Grosse AS, Iwatsuki K, Mishina Y, Gumucio DL, Mistretta CM. Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development. Developmental Biology. 361: 39-56. PMID 22024319 DOI: 10.1016/J.Ydbio.2011.10.009  0.367
2012 El-Zaatari M, Kao JY, Tessier A, Hayes MM, Gumucio DL, Merchant JL. 261 Two Hedgehog (GLI1) Gene Targets Correlate With Helicobacter-Induced Antigen-Presenting Cell Recruitment Gastroenterology. 142: S-61. DOI: 10.1016/S0016-5085(12)60239-X  0.305
2011 Grosse AS, Pressprich MF, Curley LB, Hamilton KL, Margolis B, Hildebrand JD, Gumucio DL. Cell dynamics in fetal intestinal epithelium: Implications for intestinal growth and morphogenesis Development. 138: 4423-4432. PMID 21880782 DOI: 10.1242/Jcs.100768  0.39
2011 Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL. Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochemistry and Cell Biology. 136: 191-204. PMID 21688022 DOI: 10.1007/S00418-011-0831-1  0.385
2011 Qiao XT, Gumucio DL. Current molecular markers for gastric progenitor cells and gastric cancer stem cells Journal of Gastroenterology. 46: 855-865. PMID 21626457 DOI: 10.1007/S00535-011-0413-Y  0.309
2011 Zacharias WJ, Madison BB, Kretovich KE, Walton KD, Richards N, Udager AM, Li X, Gumucio DL. Hedgehog signaling controls homeostasis of adult intestinal smooth muscle. Developmental Biology. 355: 152-62. PMID 21545794 DOI: 10.1016/J.Ydbio.2011.04.025  0.786
2011 Qiao XT, Samuelson LC, Dlugosz A, Merchant JL, Gumucio DL. Villin-Marked Gastric Epithelial Progenitor Cells Do Not Give Rise to Tumors or Metaplastic Cells in a Variety of Mouse Models Gastroenterology. 140: S-830. DOI: 10.1016/S0016-5085(11)63439-2  0.316
2011 Saqui-Salces M, Keeley TM, Samuelson LC, Gumucio DL, Merchant JL. Gastro-Intestinal Tuft Cells Are DCLK1 Positive, and Appear Late in Development Gastroenterology. 140: S-148. DOI: 10.1016/S0016-5085(11)60601-X  0.346
2011 El-Zaatari M, Kao JY, Waghray M, Gumucio DL, Merchant JL. Reduced Hedgehog Signal Transduction Exacerbates the TH1 Response in Helicobacter felis -Infected Mice Gastroenterology. 140: S-86. DOI: 10.1016/S0016-5085(11)60350-8  0.684
2011 Grosse AS, Pressprich M, Curley L, Margolis B, Hildebrand J, Gumucio D. A new model of intestinal morphogenesis: The cell dynamics of epithelial remodeling and lumen expansion Developmental Biology. 356: 147-148. DOI: 10.1016/J.Ydbio.2011.05.162  0.333
2010 Udager A, Prakash A, Gumucio DL. Dividing the tubular gut: Generation of organ boundaries at the pylorus Progress in Molecular Biology and Translational Science. 96: 35-62. PMID 21075339 DOI: 10.1016/B978-0-12-381280-3.00002-6  0.6
2010 El-Zaatari M, Zavros Y, Tessier A, Waghray M, Lentz S, Gumucio D, Todisco A, Merchant JL. Intracellular calcium release and protein kinase C activation stimulate sonic hedgehog gene expression during gastric acid secretion. Gastroenterology. 139: 2061-2071.e2. PMID 20816837 DOI: 10.1053/J.Gastro.2010.08.047  0.697
2010 Smalley-Freed WG, Efimov A, Burnett PE, Short SP, Davis MA, Gumucio DL, Washington MK, Coffey RJ, Reynolds AB. p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. The Journal of Clinical Investigation. 120: 1824-35. PMID 20484816 DOI: 10.1172/Jci41414  0.376
2010 Zacharias WJ, Li X, Madison BB, Kretovich K, Kao JY, Merchant JL, Gumucio DL. Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria. Gastroenterology. 138: 2368-77, 2377.e1-4. PMID 20206176 DOI: 10.1053/J.Gastro.2010.02.057  0.796
2010 Cheng J, Waite AL, Tkaczyk ER, Ke K, Richards N, Hunt AJ, Gumucio DL. Kinetic properties of ASC protein aggregation in epithelial cells. Journal of Cellular Physiology. 222: 738-47. PMID 20020448 DOI: 10.1002/Jcp.22005  0.768
2010 Udager AM, Prakash A, Engel JD, Lim K, Gumucio DL. 867a GATA3 is Essential for Proper Morphogenesis of the Pylorus Gastroenterology. 138: S-120. DOI: 10.1016/S0016-5085(10)60551-3  0.63
2010 El Zaatari M, Zavros Y, Tessier A, Waghray M, Lentz SI, Gumucio DL, Todisco A, Merchant JL. 853 Gastric Acid-Mediated Release of Intracellular Calcium Stimulates Sonic Hedgehog Gene Expression Gastroenterology. 138: S-117. DOI: 10.1016/S0016-5085(10)60536-7  0.662
2010 Udager AM, Parker DS, Gurdziel K, Jayaraman M, Barolo SE, Gumucio DL. 851 Phylogenomic Analysis of GLI/CI Binding Site Density and Affinity: An Integrative in Silico Approach to Identifying Hedgehog-Regulated Enhancers Gastroenterology. 138: S-116. DOI: 10.1016/S0016-5085(10)60534-3  0.535
2010 VanDussen KL, Kolterud Å, Gumucio DL, Samuelson LC. 848 Notch Signaling Induces Expression of the Intestinal Stem Cell Marker Olfactomedin 4 (OLFM4) Gastroenterology. 138: S-116. DOI: 10.1016/S0016-5085(10)60531-8  0.382
2010 Syu L, Ferris J, Qiao X, Tetarbe M, Merchant JL, Gumucio DL, Dlugosz A. 584 Transgenic Expression of Interferon Gamma in the Gastric Corpus Leads to Inflammation, Progenitor Cell Expansion, and Mucous Metaplasia Gastroenterology. 138: S-83. DOI: 10.1016/S0016-5085(10)60379-4  0.346
2010 Wang L, Lu J, Jiang S, Wakeman D, Zacharias WJ, Madison BB, Gumucio DL, Warner BW, Levin MS, Rubin DC. 555 Overexpression of Indian Hedgehog (IHH) in Enterocytes Inhibits the Crypt Cell Proliferative and Morphometric Adaptive Response in a Mouse Model of Short Bowel Syndrome Gastroenterology. 138: S-77. DOI: 10.1016/S0016-5085(10)60350-2  0.766
2009 Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL. Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life Developmental Dynamics. 238: 3205-3217. PMID 19877272 DOI: 10.1002/Dvdy.22134  0.674
2009 Liu HX, Grosse AM, Walton KD, Saims DA, Gumucio DL, Mistretta CM. WNT5a in tongue and fungiform Papilla development. Annals of the New York Academy of Sciences. 1170: 11-7. PMID 19686099 DOI: 10.1111/J.1749-6632.2009.04369.X  0.764
2009 Waite AL, Schaner P, Richards N, Balci-Peynircioglu B, Masters SL, Brydges SD, Fox M, Hong A, Yilmaz E, Kastner DL, Reinherz EL, Gumucio DL. Pyrin Modulates the Intracellular Distribution of PSTPIP1. Plos One. 4: e6147. PMID 19584923 DOI: 10.1371/Journal.Pone.0006147  0.758
2009 Gudjonsson JE, Ding J, Li X, Nair RP, Tejasvi T, Qin ZS, Ghosh D, Aphale A, Gumucio DL, Voorhees JJ, Abecasis GR, Elder JT. Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin. The Journal of Investigative Dermatology. 129: 2795-804. PMID 19571819 DOI: 10.1038/Jid.2009.173  0.411
2009 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL. Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 137: 618-28. PMID 19445942 DOI: 10.1053/J.Gastro.2009.05.002  0.785
2009 Waite AL, Schaner P, Hu C, Richards N, Balci-Peynircioglu B, Hong A, Fox M, Gumucio DL. Pyrin and ASC Co-localize to cellular sites that are rich in polymerizing actin Experimental Biology and Medicine. 234: 40-52. PMID 19109554 DOI: 10.3181/0806-Rm-184  0.773
2009 Udager AM, Li X, Qiao X, Lim K, Engel JD, Gumucio DL. M1596 GATA3 and Nephrocan Are Expressed in Highly Restricted Patterns At the Developing Pylorus Gastroenterology. 136: A-391. DOI: 10.1016/S0016-5085(09)61796-0  0.595
2009 Shinohara M, Phaosawasdi P, Mao MY, Samuelson LC, Eaton KA, Gumucio DL, Todisco A. 864 Regulation of Gastric Epithelial Homeostasis By Bone Morphogenetic Protein Signaling Gastroenterology. 136: A-132. DOI: 10.1016/S0016-5085(09)60593-X  0.324
2009 Zacharias WJ, Kao JY, Li X, Gumucio DL. 358 Constitutive Inhibition of Hedgehog (HH) Signaling Causes Intestinal Villus Atrophy, Spontaneous Small Intestinal Inflammation, and Dermatitis: A Mouse Phenocopy of Human Celiac Disease? Gastroenterology. 136: A-58. DOI: 10.1016/S0016-5085(09)60261-4  0.728
2009 Walton KD, Kolterud Å, Grosse AS, Hu C, Czerwinski M, Richards N, Gumucio DL. Epithelial Hedgehog signals direct mesenchymal villus patterning through BMP Developmental Biology. 331: 489. DOI: 10.1016/J.Ydbio.2009.05.384  0.33
2008 Lees CW, Zacharias WJ, Tremelling M, Noble CL, Nimmo ER, Tenesa A, Cornelius J, Torkvist L, Kao J, Farrington S, Drummond HE, Ho GT, Arnott ID, Appelman HD, Diehl L, ... ... Gumucio DL, et al. Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways. Plos Medicine. 5: e239. PMID 19071955 DOI: 10.1371/Journal.Pmed.0050239  0.732
2008 Yang H, Gumucio DL, Teitelbaum DH. Intestinal specific overexpression of interleukin-7 attenuates the alternation of intestinal intraepithelial lymphocytes after total parenteral nutrition administration. Annals of Surgery. 248: 849-56. PMID 18948814 DOI: 10.1097/Sla.0B013E31818A1522  0.336
2008 Balci-Peynircioglu B, Waite AL, Schaner P, Taskiran ZE, Richards N, Orhan D, Gucer S, Ozen S, Gumucio D, Yilmaz E. Expression of ASC in renal tissues of familial mediterranean fever patients with amyloidosis: postulating a role for ASC in AA type amyloid deposition. Experimental Biology and Medicine (Maywood, N.J.). 233: 1324-33. PMID 18791131 DOI: 10.3181/0803-Rm-106  0.765
2008 Chae JJ, Wood G, Richard K, Jaffe H, Colburn NT, Masters SL, Gumucio DL, Shoham NG, Kastner DL. The Familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-{kappa}B through its N-terminal fragment Blood. 112: 1794-1803. PMID 18577712 DOI: 10.1182/Blood-2008-01-134932  0.304
2008 Yang H, Madison B, Gumucio DL, Teitelbaum DH. Specific overexpression of IL-7 in the intestinal mucosa: The role in intestinal intraepithelial lymphocyte development American Journal of Physiology - Gastrointestinal and Liver Physiology. 294: G1421-G1430. PMID 18403617 DOI: 10.1152/Ajpgi.00060.2008  0.635
2008 Balci-Peynircioglu B, Waite AL, Hu C, Richards N, Staubach-Grosse A, Yilmaz E, Gumucio DL. Pyrin, product of the MEFV locus, interacts with the proapoptotic protein, Siva Journal of Cellular Physiology. 216: 595-602. PMID 18330885 DOI: 10.1002/Jcp.21435  0.77
2008 Udager AM, Li X, Qiao X, Gumucio DL. M1649 Transcriptional Control of Epithelial Cell Identity: Dynamic Expression of Cell-Intrinsic Factors During Formation of the Pyloric Border Gastroenterology. 134: A-389-A-390. DOI: 10.1016/S0016-5085(08)61819-3  0.628
2008 Zacharias WJ, Lees CW, Kao JY, Li X, Satsangi J, Gumucio DL. S1713 Epithelial Hedgehog Signals Modulate the Inflammatory Response of the Intestinal Lamina Propria Gastroenterology. 134: A-255. DOI: 10.1016/S0016-5085(08)61184-1  0.714
2007 Qiao XT, Ziel JW, McKimpson W, Madison BB, Todisco A, Merchant JL, Samuelson LC, Gumucio DL. Prospective identification of a multilineage progenitor in murine stomach epithelium. Gastroenterology. 133: 1989-98. PMID 18054570 DOI: 10.1053/J.Gastro.2007.09.031  0.671
2007 López-Díaz L, Jain RN, Keeley TM, VanDussen KL, Brunkan CS, Gumucio DL, Samuelson LC. Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate Developmental Biology. 309: 298-305. PMID 17706959 DOI: 10.1016/J.Ydbio.2007.07.015  0.389
2007 Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C, Madison B, Gumucio D, Neurath MF, Pasparakis M. Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature. 446: 557-61. PMID 17361131 DOI: 10.1038/Nature05698  0.695
2007 Li X, Madison BB, Zacharias W, Kolterud A, States D, Gumucio DL. Deconvoluting the intestine: Molecular evidence for a major role of the mesenchyme in the modulation of signaling cross talk Physiological Genomics. 29: 290-301. PMID 17299133 DOI: 10.1152/Physiolgenomics.00269.2006  0.801
2007 Becker C, Nenci A, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C, Madison B, Gumucio D, Pasparakis M, Neurath M. Spontane Ausbildung eine schweren chronisch entzündliche Darmerkrankung in Knockout-Mäusen mit defekter NF-kappaB Aktivierung in intestinalen Epithelzellen Zeitschrift FüR Gastroenterologie. 45. DOI: 10.1055/s-2007-988110  0.564
2006 Jones RG, Li X, Gray PD, Kuang J, Clayton F, Samowitz WS, Madison BB, Gumucio DL, Kuwada SK. Conditional deletion of beta1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality. The Journal of Cell Biology. 175: 505-14. PMID 17088430 DOI: 10.1083/Jcb.200602160  0.683
2006 Adachi M, Kurotani R, Morimura K, Shah Y, Sanford M, Madison BB, Gumucio DL, Marin HE, Peters JM, Young HA, Gonzalez FJ. Peroxisome proliferator activated receptor γ in colonic epithelial cells protects against experimental inflammatory bowel disease Gut. 55: 1104-1113. PMID 16547072 DOI: 10.1136/Gut.2005.081745  0.665
2006 Zacharias WJ, Madison BB, Li X, Kolterud A, Gumucio DL. Sonic and Indian hedgehog regulate intestinal villus smooth muscle differentiation Developmental Biology. 295: 453. DOI: 10.1016/J.Ydbio.2006.04.396  0.773
2005 Schaner PE, Gumucio DL. Familial Mediterranean fever in the post-genomic era: How an ancient disease is providing new insights into inflammatory pathways Current Drug Targets: Inflammation and Allergy. 4: 67-76. PMID 15720238 DOI: 10.2174/1568010053622803  0.692
2005 Madison BB, Braunstein K, Kuizon E, Portman K, Qiao XT, Gumucio DL. Epithelial hedgehog signals pattern the intestinal crypt-villus axis Development. 132: 279-289. PMID 15590741 DOI: 10.1242/Dev.01576  0.72
2005 Rieder G, Tessier AJ, Qiao XT, Madison B, Gumucio DL, Merchant JL. Helicobacter-induced intestinal metaplasia in the stomach correlates with Elk-1 and serum response factor induction of villin Journal of Biological Chemistry. 280: 4906-4912. PMID 15576363 DOI: 10.1074/Jbc.M413399200  0.676
2004 Diaz A, Hu C, Kastner DL, Schaner P, Reginato AM, Richards N, Gumucio DL. Lipopolysaccharide-induced expression of multiple alternatively spliced MEFV transcripts in human synovial fibroblasts: A prominent splice isoform lacks the C-terminal domain that is highly mutated in familial Mediterranean fever Arthritis and Rheumatism. 50: 3679-3689. PMID 15529356 DOI: 10.1002/Art.20600  0.694
2003 Masumoto J, Dowds TA, Schaner P, Chen FF, Ogura Y, Li M, Zhu L, Katsuyama T, Sagara J, Taniguchi S, Gumucio DL, Núñez G, Inohara N. ASC is an activating adaptor for NF-κB and caspase-8-dependent apoptosis Biochemical and Biophysical Research Communications. 303: 69-73. PMID 12646168 DOI: 10.1016/S0006-291X(03)00309-7  0.656
2002 Johnson RM, Gumucio D, Goodman M. Globin gene switching in primates Comparative Biochemistry and Physiology - a Molecular and Integrative Physiology. 133: 877-883. PMID 12443943 DOI: 10.1016/S1095-6433(02)00205-2  0.33
2002 Gumucio DL, Diaz A, Schaner P, Richards N, Babcock C, Schaller M, Cesena T. Fire and ICE: The role of pyrin domain-containing proteins in inflammation and apoptosis Clinical and Experimental Rheumatology. 20: S45-S53. PMID 12371636  0.672
2002 Madison BB, Dunbar L, Qiao XT, Braunstein K, Braunstein E, Gumucio DL. cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine Journal of Biological Chemistry. 277: 33275-33283. PMID 12065599 DOI: 10.1074/Jbc.M204935200  0.697
2002 Braunstein EM, Qiao XT, Madison B, Pinson K, Dunbar L, Gumucio DL. Villin: A marker for development of the epithelial pyloric border Developmental Dynamics. 224: 90-102. PMID 11984877 DOI: 10.1002/Dvdy.10091  0.688
2002 Yu T, Thomas DM, Zhu W, Goodman M, Gumucio DL. Regulation of fetal versus embryonic gamma globin genes: Appropriate developmental stage expression patterns in the presence of HS2 of the locus control region Blood. 99: 1082-1084. PMID 11807017 DOI: 10.1182/Blood.V99.3.1082  0.316
2001 Richards N, Schaner P, Diaz A, Stuckey J, Shelden E, Wadhwa A, Gumucio DL. Interaction between Pyrin and the Apoptotic Speck Protein (ASC) Modulates ASC-induced Apoptosis Journal of Biological Chemistry. 276: 39320-39329. PMID 11498534 DOI: 10.1074/Jbc.M104730200  0.696
2001 Kennell JA, Richards NW, Schaner PE, Gumucio DL. cDNA cloning, chromosomal localization and evolutionary analysis of mouse vacuolar ATPase subunit D, Atp6m Cytogenetics and Cell Genetics. 92: 337-341. PMID 11435709 DOI: 10.1159/000056924  0.619
2001 Schaner P, Richards N, Wadhwa A, Aksentijevich I, Kastner D, Tucker P, Gumucio D. Episodic evolution of pyrin in primates: human mutations recapitulate ancestral amino acid states. Nature Genetics. 27: 318-21. PMID 11242116 DOI: 10.1038/85893  0.664
2000 Johnson RM, Buck S, Chiu CH, Gage DA, Shen TL, Hendrickx AG, Gumucio DL, Goodman M. Humans and Old World monkeys have similar patterns of fetal globin expression Journal of Experimental Zoology. 288: 318-326. PMID 11144280 DOI: 10.1002/1097-010X(20001215)288:4<318::Aid-Jez4>3.0.Co;2-0  0.304
1999 Chiu CH, Gregoire L, Gumucio DL, Muniz JA, Lancaster WD, Goodman M. Model for the fetal recruitment of simian gamma-globin genes based on findings from two New World monkeys Cebus apella and Callithrix jacchus (Platyrrhini, Primates). The Journal of Experimental Zoology. 285: 27-40. PMID 10327648 DOI: 10.1002/(Sici)1097-010X(19990415)285:1<27::Aid-Jez4>3.0.Co;2-0  0.306
1999 Zhu W, TomHon C, Mason M, Campbell T, Shelden E, Richards N, Goodman M, Gumucio DL. Analysis of linked human ε and γ transgenes: Effect of locus control region hypersensitive sites 2 and 3 or a distal YY1 mutation on stage- specific expression patterns Blood. 93: 3540-3549. PMID 10233907 DOI: 10.1182/Blood.V93.10.3540.410K28_3540_3549  0.346
1998 Pinson KI, Dunbar L, Samuelson L, Gumucio DL. Targeted disruption of the mouse villin gene does not impair the morphogenesis of microvilli Developmental Dynamics. 211: 109-121. PMID 9438428 DOI: 10.1002/(Sici)1097-0177(199801)211:1<109::Aid-Aja10>3.0.Co;2-7  0.398
1997 Hardison R, Slightom JL, Gumucio DL, Goodman M, Stojanovic N, Miller W. Locus control regions of mammalian β-globin gene clusters: Combining phylogenetic analyses and experimental results to gain functional insights Gene. 205: 73-94. PMID 9461381 DOI: 10.1016/S0378-1119(97)00474-5  0.3
1997 Shelton DA, Stegman L, Hardison R, Miller W, Bock JH, Slightom JL, Goodman M, Gumucio DL. Phylogenetic footprinting of hypersensitive site 3 of the β-globin locus control region Blood. 89: 3457-3469. DOI: 10.1182/Blood.V89.9.3457  0.324
1996 Gumucio DL, Shelton DA, Zhu W, Millinoff D, Gray T, Bock JH, Slightom JL, Goodman M. Evolutionary strategies for the elucidation of cis and trans factors that regulate the developmental switching programs of the beta-like globin genes. Molecular Phylogenetics and Evolution. 5: 18-32. PMID 8673285 DOI: 10.1006/Mpev.1996.0004  0.327
1993 Gumucio DL, Shelton DA, Bailey WJ, Slightom JL, Goodman M. Phylogenetic footprinting reveals unexpected complexity in trans factor binding upstream from the epsilon-globin gene. Proceedings of the National Academy of Sciences of the United States of America. 90: 6018-22. PMID 8327477 DOI: 10.1073/Pnas.90.13.6018  0.333
1993 Jane SM, Gumucio DL, Ney PA, Cunningham JM, Nienhuis AW. Methylation-enhanced binding of Sp1 to the stage selector element of the human gamma-globin gene promoter may regulate development specificity of expression. Molecular and Cellular Biology. 13: 3272-81. PMID 7684493 DOI: 10.1128/Mcb.13.6.3272  0.332
1992 Gumucio DL, Heilstedt-Williamson H, Gray TA, Tarlé SA, Shelton DA, Tagle DA, Slightom JL, Goodman M, Collins FS. Phylogenetic footprinting reveals a nuclear protein which binds to silencer sequences in the human γ and ε globin genes Molecular and Cellular Biology. 12: 4919-4929. PMID 1406669 DOI: 10.1128/mcb.12.11.4919-4929.1992  0.321
1991 Traber PG, Gumucio DL, Wang W. Isolation of intestinal epithelial cells for the study of differential gene expression along the crypt-villus axis American Journal of Physiology - Gastrointestinal and Liver Physiology. 260: G895-G903. PMID 2058677 DOI: 10.1152/Ajpgi.1991.260.6.G895  0.358
1990 Gumucio DL, Lockwood WK, Weber JL, Saulino AM, Delgrosso K, Surrey S, Schwartz E, Goodman M, Collins FS. The -175T → C mutation increases promoter strength in erythroid cells: Correlation with evolutionary conservation of binding sites for two trans-acting factors Blood. 75: 756-761. PMID 1688723 DOI: 10.1182/Blood.V75.3.756.Bloodjournal753756  0.362
1988 Gumucio DL, Rood KL, Gray TA, Riordan MF, Sartor CI, Collins FS. Nuclear proteins that bind the human gamma-globin gene promoter: alterations in binding produced by point mutations associated with hereditary persistence of fetal hemoglobin. Molecular and Cellular Biology. 8: 5310-22. PMID 2468996 DOI: 10.1128/mcb.8.12.5310-5322.1988  0.326
1988 Samuelson LC, Wiebauer K, Gumucio DL, Meisler MH. Expression of the human amylase genes: Recent origin of a salivary amylase promoter from an actin pseudogene Nucleic Acids Research. 16: 8261-8276. PMID 2458567 DOI: 10.1093/Nar/16.17.8261  0.305
1986 Darlington GJ, Tsai CC, Samuelson LC, Gumucio DL, Meisler MH. Simultaneous expression of salivary and pancreatic amylase genes in cultured mouse hepatoma cells Molecular and Cellular Biology. 6: 969-975. PMID 2431276 DOI: 10.1128/Mcb.6.4.969  0.364
Show low-probability matches.