Yong Ma, Ph.D.

Hedgehog proteins and other extracellular signals in morphogenesis

Philip A. Beachy	grad student	2003	Johns Hopkins
(Genetic and biochemical analysis of dispatched function in Hedgehog signaling.)

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Wang Q, Asarnow DE, Ding K, et al. (2021) Dispatched uses Na flux to power release of lipid-modified Hedgehog. Nature
Roessler E, Ma Y, Ouspenskaia MV, et al. (2009) Truncating loss-of-function mutations of DISP1 contribute to holoprosencephaly-like microform features in humans. Human Genetics. 125: 393-400
Echeverri CJ, Beachy PA, Baum B, et al. (2006) Minimizing the risk of reporting false positives in large-scale RNAi screens. Nature Methods. 3: 777-9
Ma Y, Creanga A, Lum L, et al. (2006) Prevalence of off-target effects in Drosophila RNA interference screens. Nature. 443: 359-63
Ma Y, Erkner A, Gong R, et al. (2002) Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell. 111: 63-75
Chen CH, von Kessler DP, Park W, et al. (1999) Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression. Cell. 98: 305-16
Porter JA, Ekker SC, Park WJ, et al. (1996) Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain. Cell. 86: 21-34