Shenqin Yao, Ph.D.

Hedgehog proteins and other extracellular signals in morphogenesis

Philip A. Beachy	grad student	2006	Johns Hopkins
(Identification of a novel hedgehog receptor from a systematic survey of the Drosophila genome.)

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McLellan JS, Yao S, Zheng X, et al. (2006) Structure of a heparin-dependent complex of Hedgehog and Ihog. Proceedings of the National Academy of Sciences of the United States of America. 103: 17208-13
Yao S, Lum L, Beachy P. (2006) The ihog cell-surface proteins bind Hedgehog and mediate pathway activation. Cell. 125: 343-57
Lum L, Yao S, Mozer B, et al. (2003) Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science (New York, N.Y.). 299: 2039-45
Ma Y, Erkner A, Gong R, et al. (2002) Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell. 111: 63-75