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Elizabeth A. Komives

Affiliations:

University of California, San Diego, La Jolla, CA

Area:

Structure, function, dynamics and thermodynamics of protein-protein interactions: NMR, mass spectrometry and kinetics

Website:

http://www-chem.ucsd.edu/faculty/profiles/komives_elizabeth_a.html

Google:

"Elizabeth Komives"

Bio:

http://komiveslab.ucsd.edu/elizabeth.html

Mean distance: 7.4

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Parents

Paul R. Ortiz de Montellano	grad student	1987	UCSF
(Mechanism of [pi]-bond oxidation by cytochrome P-450 : acetylenes as probes)
Jeremy R. Knowles	post-doc	1987-1990	Harvard

Children

Mia A. Rosenfeld	grad student
Kristen M. Ramsey	grad student	2013-	UCSD
Jason R. Greenwald	grad student	2000	UCSD
Jeffrey G. Mandell	grad student	2000	UCSD
Abel Baerga-Ortiz	grad student	2001	UCSD
Kerney J. Glover	grad student	2001	UCSD
Johnny E. Croy	grad student	2003	UCSD
Carrie A. Hughes	grad student	2003	UCSD
Judith H. Prieto	grad student	2005	UCSD
Erin K. Wallace	grad student	2005	UCSD
Joon H. Huh	grad student	2006	UCSD
Julia R. Koeppe	grad student	2006	UCSD
Matthew J. Hotchko	grad student	2007	UCSD
Gina F. Nubile	grad student	2007	UCSD
Muneera A. Beach	grad student	2008	UCSD
Miklos Guttman	grad student	2009	UCSD
Carla F. Cervantes	grad student	2010	UCSD
Nikki Dellas	grad student	2010	UCSD
Ingrid L. DeVries	grad student	2011	UCSD
Melinda M. Mulvihill	grad student	2011	UCSD
Akos Nemecz	grad student	2011	UCSD
Brian A. Fuglestad	grad student	2013	UCSD
Nicholas A. Treuheit	grad student	2013	UCSD

Collaborators

BETA: Related publications

Publications

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Komives EA. (2023) Dynamic allostery in thrombin-a review. Frontiers in Molecular Biosciences. 10: 1200465
Sabo KA, Albekioni E, Caliger D, et al. (2023) Capturing the Dynamic Conformational Changes of Human Isocitrate Dehydrogenase 1 (IDH1) upon Ligand and Metal Binding Using Hydrogen-Deuterium Exchange Mass Spectrometry. Biochemistry
Molina JA, Galaz-Davison P, Komives EA, et al. (2022) Allosteric couplings upon binding of RfaH to transcription elongation complexes. Nucleic Acids Research
Peacock RB, McGrann T, Zaragoza S, et al. (2022) How Thrombomodulin Enables W215A/E217A Thrombin to Cleave Protein C but Not Fibrinogen. Biochemistry. 61: 77-84
Peacock RB, McGrann T, Tonelli M, et al. (2021) Serine protease dynamics revealed by NMR analysis of the thrombin-thrombomodulin complex. Scientific Reports. 11: 9354
Medina E, Villalobos P, Hamilton GL, et al. (2020) Intrinsically disordered regions of the DNA-binding domain of human FoxP1 facilitate domain swapping. Journal of Molecular Biology
Lumpkin RJ, Baker RW, Leschziner AE, et al. (2020) Structure and dynamics of the ASB9 CUL-RING E3 Ligase. Nature Communications. 11: 2866
Engen JR, Komives EA. (2020) Complementarity of Hydrogen/Deuterium Exchange Mass Spectrometry and Cryo-Electron Microscopy. Trends in Biochemical Sciences
Zamora RA, Ramirez-Sarmiento CA, Castro-Fernández V, et al. (2020) Tuning of Conformational Dynamics Through Evolution-Based Design Modulates the Catalytic Adaptability of an Extremophilic Kinase Acs Catalysis. 10847-10857
Torres-Paris C, Xiao L, Chen Y, et al. (2020) The N-Terminal Fragment (ATF) Regulates the Dynamics and the Activity of the Protease Domain of the Urokinase-Type Plasminogen Activator (uPA) Biophysical Journal. 118: 53a