Tom Maniatis, Phd
Affiliations: | Biochemistry and Molecular Biophysics | Harvard University, Cambridge, MA, United States | |
| Columbia University, New York, NY |
Area:
Regulation of RNA Transcription and Splicing, The Role of Neuroinflammation in ALS, Neurobiology of Disease, Synapses and Circuits, Stem Cell Biology, ALS Disease Mechanisms, Genetic Basis of Neurological DiseasesWebsite:
http://biochemistry.hs.columbia.edu/faculty/maniatis.htmGoogle:
"Tom Maniatis"Bio:
http://www.nasonline.org/member-directory/members/45746.html
http://www.maniatislab.columbia.edu/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461937/
http://en.wikipedia.org/wiki/Tom_Maniatis
Cross-listing: Cell Biology Tree - Chemistry Tree - Neurotree
Parents
Sign in to add mentor| Leonard S. Lerman | grad student | 1971 | Vanderbilt (Chemistry Tree) | |
| (The structure of DNA after phase separation from aqueous polymer solutions) | ||||
| Mark Ptashne | post-doc | Harvard | ||
| Frederick Sanger | post-doc | MRC-LMB | ||
Children
Sign in to add trainee| Michelle C. Siao | research assistant | 2005-2010 | Harvard (Neurotree) |
| Christopher J. Griffey | research assistant | 2014-2016 | (Neurotree) |
| Victoria Lynn Corbin | grad student | ||
| Adrian R. Krainer | grad student | Harvard (Neurotree) | |
| Kristen Lynch | grad student | Penn (Neurotree) | |
| Robin Reed | grad student | Harvard (Neurotree) | |
| Kai Zinn | grad student | ||
| Brian Seed | grad student | 1981 | Caltech (Chemistry Tree) |
| Ted Abel | grad student | 1987-1993 | Harvard (Neurotree) |
| Bing Ren | grad student | 1998 | Harvard (Chemistry Tree) |
| Christopher P. Sears | grad student | 2001 | Harvard |
| Zhaolan Zhou | grad student | 2001 | Harvard |
| Chih-Hsuan Lin | grad student | 2002 | Harvard |
| Tae Hoon Kim | grad student | 1996-2002 | Harvard (Chemistry Tree) |
| Rui Zhou | grad student | 2003 | Harvard |
| Shuning Liao | grad student | 2004 | Harvard (Cell Biology Tree) |
| Bosiljka Tasic | grad student | 2004 | Harvard (Neurotree) |
| Scott A. Ribich | grad student | 2005 | Harvard |
| Sean M. Buchanan | grad student | 2009 | Harvard |
| Sze-Ling Ng | grad student | 2010 | Harvard |
| Kevin G. Monahan | grad student | 2011 | Harvard |
| Emiko T. Morimoto | grad student | 2012 | Harvard |
| GEORGE MOUNTOUFARIS | grad student | 2009-2016 | Columbia (Neurotree) |
| Hubert Amrein | post-doc | ||
| Patrick Charnay | post-doc | Harvard (Neurotree) | |
| Cansu Karabiyik | post-doc | Columbia (Neurotree) | |
| Alan Michelson | post-doc | Harvard | |
| James W. Posakony | post-doc | Harvard | |
| Nicholas Proudfoot | post-doc | CSHL (Chemistry Tree) | |
| Gary Struhl | post-doc | Harvard University, Columbia University | |
| Weisheng Victor Chen | post-doc | 2009- | Columbia (Neurotree) |
| Lydia Villa-Komaroff | post-doc | 1976 | Harvard (Cell Biology Tree) |
| Ross C. Hardison | post-doc | 1977-1980 | Caltech (Cell Biology Tree) |
| Daniel C. DiMaio | post-doc | 1981-1983 | Harvard (Chemistry Tree) |
| Micheal R. Green | post-doc | 1984 | Harvard (Neurotree) |
| Richard Morris Myers | post-doc | 1982-1985 | Harvard (Neurotree) |
| Xiang-Dong Fu | post-doc | 1990-1992 | Harvard (Chemistry Tree) |
| Jane Ying Wu | post-doc | 1992-1997 | Harvard (Neurotree) |
| Brenton R. Graveley | post-doc | 1996-1999 | Harvard |
| Qiang Wu | post-doc | 1998-2001 | (Neurotree) |
| Isaac Chiu | post-doc | 2009-2010 | MCB Harvard University (Neurotree) |
| Hemali P. Phatnani | post-doc | 2006-2013 | Columbia (Chemistry Tree) |
BETA: Related publications
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Publications
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| Flaherty E, Maniatis T. (2020) The role of clustered protocadherins in neurodevelopment and neuropsychiatric diseases. Current Opinion in Genetics & Development. 65: 144-150 |
| Gerbino V, Kaunga E, Ye J, et al. (2020) The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice. Neuron |
| Ye J, Cheung J, Gerbino V, et al. (2019) Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity. Proceedings of the National Academy of Sciences of the United States of America |
| Canzio D, Maniatis T. (2019) The generation of a protocadherin cell-surface recognition code for neural circuit assembly. Current Opinion in Neurobiology. 59: 213-220 |
| Canzio D, Nwakeze CL, Horta A, et al. (2019) Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice. Cell |
| Gelfman S, Dugger SA, Araujo Martins Moreno C, et al. (2019) A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS. Genome Research |
| Mountoufaris G, Canzio D, Nwakeze CL, et al. (2018) Writing, Reading, and Translating the Clustered Protocadherin Cell Surface Recognition Code for Neural Circuit Assembly. Annual Review of Cell and Developmental Biology. 34: 471-493 |
| Yuan Y, Xie S, Darnell JC, et al. (2018) Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons. Genome Biology. 19: 117 |
| Rudnick ND, Griffey CJ, Guarnieri P, et al. (2017) Distinct roles for motor neuron autophagy early and late in the SOD1(G93A) mouse model of ALS. Proceedings of the National Academy of Sciences of the United States of America |
| Rizvi AH, Camara PG, Kandror EK, et al. (2017) Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development. Nature Biotechnology |