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Kamil Slowikowski - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Website:
http://slowkow.com
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Blum SM, Zlotoff DA, Smith NP, Kernin IJ, Ramesh S, Zubiri L, Caplin J, Samanta N, Martin S, Wang M, Tirard A, Song Y, Xu KH, Barth J, Sen P, ... Slowikowski K, et al. Immune responses in checkpoint myocarditis across heart, blood and tumour. Nature. PMID 39506125 DOI: 10.1038/s41586-024-08105-5  0.315
2024 Thomas MF, Slowikowski K, Manakongtreecheep K, Sen P, Samanta N, Tantivit J, Nasrallah M, Zubiri L, Smith NP, Tirard A, Ramesh S, Arnold BY, Nieman LT, Chen JH, Eisenhaure T, et al. Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in checkpoint inhibitor colitis. Nature Medicine. PMID 38724705 DOI: 10.1038/s41591-024-02895-x  0.317
2023 Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, ... ... Slowikowski K, et al. Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. Nature. PMID 37938773 DOI: 10.1038/s41586-023-06708-y  0.615
2023 Blum SM, Zlotoff DA, Smith NP, Kernin IJ, Ramesh S, Zubiri L, Caplin J, Tirard A, Sen P, Song Y, Barth J, Slowikowski K, Nasrallah M, Tantivit J, Manakongtreecheep K, et al. Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor. Biorxiv : the Preprint Server For Biology. PMID 37790460 DOI: 10.1101/2023.09.15.557794  0.311
2021 Muus C, Luecken MD, Eraslan G, Sikkema L, Waghray A, Heimberg G, Kobayashi Y, Vaishnav ED, Subramanian A, Smillie C, Jagadeesh KA, Duong ET, Fiskin E, Triglia ET, Ansari M, ... ... Slowikowski K, et al. Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nature Medicine. PMID 33654293 DOI: 10.1038/s41591-020-01227-z  0.324
2020 Fan J, Slowikowski K, Zhang F. Single-cell transcriptomics in cancer: computational challenges and opportunities. Experimental & Molecular Medicine. PMID 32929226 DOI: 10.1038/S12276-020-0422-0  0.407
2020 Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM, Slowikowski K, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, et al. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Science Advances. 6: eaba4353. PMID 32637608 DOI: 10.1126/Sciadv.Aba4353  0.545
2020 Asgari S, Luo Y, Akbari A, Belbin GM, Li X, Harris DN, Selig M, Bartell E, Calderon R, Slowikowski K, Contreras C, Yataco R, Galea JT, Jimenez J, Coit JM, et al. A positively selected FBN1 missense variant reduces height in Peruvian individuals. Nature. PMID 32499652 DOI: 10.1038/S41586-020-2302-0  0.503
2020 Knevel R, le Cessie S, Terao CC, Slowikowski K, Cui J, Huizinga TWJ, Costenbader KH, Liao KP, Karlson EW, Raychaudhuri S. Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis. Science Translational Medicine. 12. PMID 32461333 DOI: 10.1126/Scitranslmed.Aay1548  0.534
2020 Slowikowski K, Nguyen HN, Noss EH, Simmons DP, Mizoguchi F, Watts GFM, Gurish MF, Brenner MB, Raychaudhuri S. CUX1 and IκBζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. PMID 32079724 DOI: 10.1073/Pnas.1912702117  0.476
2020 Thomas M, Slowikowski K, Nasrallah M, Manakongtreecheep K, Jessica T, Leyre Z, Khalili H, Reynolds K, Dougan M, Hacohen N, Villani A. 318 SINGLE CELL DISSECTION OF THE TRANSCRIPTIONAL LANDSCAPE DEFINING CHECKPOINT INHIBITOR-ASSOCIATED COLITIS OPENS A WINDOW INTO IMMUNE DYSREGULATION IN THE HUMAN COLON Gastroenterology. 158: S-57. DOI: 10.1016/S0016-5085(20)30825-8  0.344
2019 Korsunsky I, Millard N, Fan J, Slowikowski K, Zhang F, Wei K, Baglaenko Y, Brenner M, Loh PR, Raychaudhuri S. Fast, sensitive and accurate integration of single-cell data with Harmony. Nature Methods. PMID 31740819 DOI: 10.1038/S41592-019-0619-0  0.594
2019 Der E, Suryawanshi H, Morozov P, Kustagi M, Goilav B, Ranabothu S, Izmirly P, Clancy R, Belmont HM, Koenigsberg M, Mokrzycki M, Rominieki H, Graham JA, Rocca JP, Bornkamp N, ... ... Slowikowski K, et al. Author Correction: Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways. Nature Immunology. PMID 31605099 DOI: 10.1038/S41590-019-0529-4  0.544
2019 Arazi A, Rao DA, Berthier CC, Davidson A, Liu Y, Hoover PJ, Chicoine A, Eisenhaure TM, Jonsson AH, Li S, Lieb DJ, Zhang F, Slowikowski K, Browne EP, Noma A, et al. Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis. Nature Immunology. PMID 31409923 DOI: 10.1038/S41590-019-0473-3  0.526
2019 Arazi A, Rao DA, Berthier CC, Davidson A, Liu Y, Hoover PJ, Chicoine A, Eisenhaure TM, Jonsson AH, Li S, Lieb DJ, Zhang F, Slowikowski K, Browne EP, Noma A, et al. The immune cell landscape in kidneys of patients with lupus nephritis. Nature Immunology. PMID 31209404 DOI: 10.1038/S41590-019-0398-X  0.633
2019 Der E, Suryawanshi H, Morozov P, Kustagi M, Goilav B, Ranabathou S, Izmirly P, Clancy R, Belmont HM, Koenigsberg M, Mokrzycki M, Rominieki H, Graham JA, Rocca JP, Bornkamp N, ... ... Slowikowski K, et al. Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways. Nature Immunology. PMID 31110316 DOI: 10.1038/S41590-019-0386-1  0.563
2019 Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, et al. Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. Nature Immunology. PMID 31061532 DOI: 10.1038/S41590-019-0378-1  0.769
2019 Gutierrez-Arcelus M, Teslovich N, Mola AR, Polidoro RB, Nathan A, Kim H, Hannes S, Slowikowski K, Watts GFM, Korsunsky I, Brenner MB, Raychaudhuri S, Brennan PJ. Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions. Nature Communications. 10: 687. PMID 30737409 DOI: 10.1038/S41467-019-08604-4  0.583
2019 Der E, Suryawanshi H, Morozov P, Kustagi M, Goilav B, Ranabothu S, Izmirly P, Clancy R, Belmont M, Koenigsberg M, Mokrzycki M, Rominiecki H, Graham J, Rocca J, Bornkamp N, ... ... Slowikowski K, et al. 300 Insights from single-cell RNA sequencing of skin and kidney in lupus nephritis Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.300  0.578
2018 Davenport EE, Amariuta T, Gutierrez-Arcelus M, Slowikowski K, Westra HJ, Luo Y, Shen C, Rao DA, Zhang Y, Pearson S, von Schack D, Beebe JS, Bing N, John S, Vincent MS, et al. Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial. Genome Biology. 19: 168. PMID 30340504 DOI: 10.1186/S13059-018-1560-8  0.698
2018 Fonseka CY, Rao DA, Teslovich NC, Korsunsky I, Hannes SK, Slowikowski K, Gurish MF, Donlin LT, Lederer JA, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Todd DJ, Bykerk VP, et al. Mixed-effects association of single cells identifies an expanded effector CD4 T cell subset in rheumatoid arthritis. Science Translational Medicine. 10. PMID 30333237 DOI: 10.1126/Scitranslmed.Aaq0305  0.77
2018 Donlin LT, Rao DA, Wei K, Slowikowski K, McGeachy MJ, Turner JD, Meednu N, Mizoguchi F, Gutierrez-Arcelus M, Lieb DJ, Keegan J, Muskat K, Hillman J, Rozo C, Ricker E, et al. Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue. Arthritis Research & Therapy. 20: 139. PMID 29996944 DOI: 10.1186/S13075-018-1631-Y  0.594
2018 Finucane HK, Reshef YA, Anttila V, Slowikowski K, Gusev A, Byrnes A, Gazal S, Loh PR, Lareau C, Shoresh N, Genovese G, Saunders A, Macosko E, Pollack S, et al. Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. Nature Genetics. 50: 621-629. PMID 29632380 DOI: 10.1038/S41588-018-0081-4  0.569
2018 Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, et al. Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. Nature Communications. 9: 789. PMID 29476097 DOI: 10.1038/S41467-018-02892-Y  0.621
2018 Knevel R, Terao C, Cui J, Slowikowski K, Huizinga T, Karlson B, Liao K, Cessie Sl, Raychaudhuri S. OP0363 Optimisingprecision medicine by using genetics to assign diagnostic prior probabilities to patients with synovitis – proof of principle Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2018-Eular.4918  0.466
2017 Slowikowski K, Wei K, Brenner MB, Raychaudhuri S. Functional genomics of stromal cells in chronic inflammatory diseases. Current Opinion in Rheumatology. PMID 28984647 DOI: 10.1097/Bor.0000000000000455  0.606
2017 Kosmicki JA, Samocha KE, Howrigan DP, Sanders SJ, Slowikowski K, Lek M, Karczewski KJ, Cutler DJ, Devlin B, Roeder K, Buxbaum JD, Neale BM, MacArthur DG, Wall DP, Robinson EB, et al. Refining the role of de novo protein-truncating variants in neurodevelopmental disorders by using population reference samples. Nature Genetics. PMID 28191890 DOI: 10.1038/Ng.3789  0.473
2017 Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, et al. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 542: 110-114. PMID 28150777 DOI: 10.1038/Nature20810  0.768
2016 van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Mateo Leach I, Eijgelsheim M, Sotoodehnia N, Hayward C, Sorice R, Meirelles O, Lyytikäinen LP, Polašek O, ... ... Slowikowski K, et al. 52 Genetic Loci Influencing Myocardial Mass. Journal of the American College of Cardiology. 68: 1435-48. PMID 27659466 DOI: 10.1016/J.Jacc.2016.07.729  0.631
2016 Han B, Pouget JG, Slowikowski K, Stahl E, Lee CH, Diogo D, Hu X, Park YR, Kim E, Gregersen PK, Dahlqvist SR, Worthington J, Martin J, Eyre S, Klareskog L, et al. A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases. Nature Genetics. PMID 27182969 DOI: 10.1038/Ng.3572  0.668
2015 Trynka G, Westra HJ, Slowikowski K, Hu X, Xu H, Stranger BE, Klein RJ, Han B, Raychaudhuri S. Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci. American Journal of Human Genetics. 97: 139-52. PMID 26140449 DOI: 10.1016/J.Ajhg.2015.05.016  0.742
2014 Hu X, Kim H, Raj T, Brennan PJ, Trynka G, Teslovich N, Slowikowski K, Chen WM, Onengut S, Baecher-Allan C, De Jager PL, Rich SS, Stranger BE, Brenner MB, Raychaudhuri S. Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells. Plos Genetics. 10: e1004404. PMID 24968232 DOI: 10.1371/Journal.Pgen.1004404  0.784
2014 Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, ... ... Slowikowski K, et al. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics. 46: 826-36. PMID 24952745 DOI: 10.1038/Ng.3014  0.594
2014 Slowikowski K, Hu X, Raychaudhuri S. SNPsea: an algorithm to identify cell types, tissues and pathways affected by risk loci. Bioinformatics (Oxford, England). 30: 2496-7. PMID 24813542 DOI: 10.1093/Bioinformatics/Btu326  0.687
2014 Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, et al. Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science (New York, N.Y.). 343: 1246980. PMID 24604203 DOI: 10.1126/Science.1246980  0.554
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